Sci-Fi Horror is a Sub-Genre of both Science Fiction and Horror that uses scientific advances or futuristic settings as a source of fear.
Notably, the first Sci-Fi genre worknote was also one of the first works in this sub-genre: Mary Shelley's Frankenstein, published in 1818.
The broad variation of the parent genres allow for a multitude of ways this can play out: scientific advancements being used for evil ends or creating new, dangerous lifeforms; man's hubris leading to horrific consequences because of our reliance on technology; alien monsters menacing the characters; or the vast loneliness of outer space being a source of ontological dread, branching into Cosmic Horror Story and Space Isolation Horror. Compare and contrast Digital Horror.
Tropes:
- After the End: The story takes place after the end of civilization, with all the remaining humans struggling for continued survival.
- A.I. Is a Crapshoot: Artificial intelligence can and will go crazy.
- Alien Abduction: Aliens kidnap humans, often for sinister purposes.
- Alien Invasion: Aliens plan to attack and conquer Earth.
- Aliens Are Bastards: Aliens are invariably shown to be Always Chaotic Evil.
- Animalistic Abomination: A particularly freakish beast.
- Apocalypse How: There are many different ways for a doomsday scenario to happen, all of them varying degrees of horrible.
- Artificial Zombie: Who needs voodoo and dark magic to raise the dead when you got nanites and cyborg implants?
- Assimilation Plot: A creature or machine wants to subdue humanity and turn them into more of itself.
- Attack of the 50-Foot Whatever: A giant (something) goes on a rampage.
- Beauty In Assimilation: Be not afraid of our Hive Mind, for it is beautiful.
- Beware the Superman: A super-powered individual abuses their abilities to rule over normal people.
- Bioweapon Beast: Some monsters aren't born but are merely made.
- Blob Monster: Evil had no shape.
- Body Horror: Unsettling and painful anatomy or mutilation.
- Botanical Abomination: A powerful, plantlike monster.
- Brown Note Being: An entity who prove to be detrimental to anyone experiencing it with their senses.
- Came from the Sky
- Chest Burster
- Contagious A.I.: Better make sure your antivirus software is up to snuff.
- Cosmic Horror Story: A horror genre dealing with humanity's insignificance in the face of inscrutable beings.
- Cybernetics Eat Your Soul: After becoming a cyborg, a person becomes corrupted by their cybernetic parts.
- Digital Abomination: A powerful, horrific intelligence born in Cyberspace.
- Dramatic Space Drifting
- Eldritch Abomination: An ancient and powerful being of unknown origins.
- Eldritch Ocean Abyss: There is something lurking deep under the sea, and it is not friendly...
- The End of the World as We Know It: A catastrophic disaster results in the total collapse of global human civilization, killing countless people in the process.
- Evil Elevator
- Evil Phone
- Evilutionary Biologist: An evil geneticist who has the goal of improving the human race on their terms.
- Face Full of Alien Wing-Wong: A human gets impregnated by aliens.
- Face Hugger
- Freak Lab Accident
- Genetic Abomination: Indescribably scary eldritch-looking monstrosities born from genetic engineering.
- Ghost Planet
- Gone Horribly Right: The solution becomes a new problem due to working too well.
- Gone Horribly Wrong: The solution fails spectacularly.
- Haunted Technology
- Helicopter Flyswatter
- Homicide Machines
- Humanoid Abomination: A being lurking deeply in Homo sapiens' uncanny valley.
- Hyperspace Is a Scary Place: Where you're going, you won't need mouths to scream.
- Industrialized Evil
- Inscrutable Aliens: You cannot understand the thoughts of these extraterrestrials.
- It Won't Turn Off: A machine stays active even when the switch is flipped in the "off" position and/or power is severed.
- Killer Robot
- Living Battery
- Mad Scientist: An insane scientist who conducts bizarre and dangerous experiments. They can sometimes get away scot free, but a lot of the times they're almost always punished or even killed showing how their hubris pushed them too far.
- Mad Scientist Laboratory: The laboratory where a mad scientist conducts their experiments.
- Man in the Machine
- Meat Moss
- Meat-Sack Robot: A cyborg who started out as fully robotic before grafting organic body parts onto its being.
- Mechanical Abomination: A machine or A.I. with the capabilities of a god.
- Mechanical Monster
- Mind-Reformat Death
- Nuclear Mutant: Exposure to radiation mutates people into monsters or supervillains.
- People Farms
- Planet Eater: A being who eats planets.
- Planetary Parasite: A massive creature that sucks the nutrients of a hapless planet
- Planet Looters: Aliens who steal resources from other planets.
- Puny Earthlings
- Puppeteer Parasite: A creature that latches onto people and controls their bodies like puppets.
- Robotic Undead
- Science Is Bad: The story has the moral that scientific progress is evil.
- SkeleBot 9000: A robot with a skeletal appearance.
- Space Isolation Horror: In space no one can hear you scream.
- Space Madness
- Spawn Broodling
- The Stars Are Going Out
- Starfish Aliens: Extraterrestrials who don't abide with familiar body shapes and physiology.
- Superhero Horror: A superhero story that's played for horror or invokes a lot of classic horror tropes.
- Techno Dystopia
- They Look Like Us Now
- To Serve Man: Humans are tasty meals for predatory aliens and other monsters.
- Transformation Horror: Horrifically being transformed into something against one's will.
- Transhuman Abomination: Once human, now horribly inhuman and godlike.
- Turned Against Their Masters: A machine puts their creators on a hit list.
- Undead Abomination: A vile necromatic being.
- Unwilling Roboticisation: A human is converted into a robot or cyborg against their will.
- Virtual Ghost
- The Virus: An infectious disease that turns people into predatory monsters.
- Wetware Body
- Zombie Apocalypse: A global pandemic results in most people around the world dying and/or turning into monsters.
Works:
- Alien/Predator/AVP franchise(s):
- Danganronpa
- Dead Space
- Frankenstein
- Ghostbusters combines supernatural horrors, Weird Science, and comedy in all its iterations.
- Resident Evil
- Terminator, while primarily better known as an action franchise, does have plenty of horror elements, particularly the first movie, which plays out like a Slasher Film that just happens to have a time-traveling Austrian-accented robot as the killer.
- AKIRA
- Alien Nine
- Bio-Hunter
- Bio-Meat: Nectar
- Biomega
- Blame!
- Blue Gender
- Brynhildr in the Darkness
- B: The Beginning
- Danganronpa
- Deadman Wonderland
- Denjin N
- Drifting Classroom
- Elfen Lied
- Emerging
- Fourteen
- Franken Fran
- Gantz, which combines aliens, monsters, and high-tech weaponry with a Deadly Game and plenty of Gorn.
- Genocyber
- Guy: Double Target
- Gyo
- Hero Mask
- Iczer-One
- Inuyashiki, from the same author of Gantz, although much less gory.
- Key the Metal Idol
- King of Thorn
- Knights of Sidonia
- Mars of Destruction
- Manhole
- Milk Closet
- MPD Psycho
- Neon Genesis Evangelion
- Parasyte
- Real Account
- Remina
- Resident Evil
- Serial Experiments Lain
- TerraforMARS
- Vampire Wars (Please note that the reason why it belongs here is a massive spoiler, so potential viewers should proceed with caution while reading about it.)
- Alien
- The Beauty
- Black Gas
- Caliban
- Carnage
- The End (Marvel Comics): A thematic series of After the End comics by Marvel Comics.
- Hollow Heart
- El Eternauta
- The Evil Within
- Fanboys Vs Zombies
- The Frankenstein Monster
- Ghost Rider 2099
- Jason X Special
- Immortal Hulk
- Judge Dredd has used its dystopian sci-fi setting for anything from drama to action to comedy, as well as horror. For instance, Dark Justice sees Dredd and Anderson battle the Dark Judges on a Ghost Ship in space.
- Man-Thing
- Morbius
- Nameless (2015)
- Outer Darkness
- Sherlock Holmes and the Horror of Frankenstein
- Southern Cross
- Swamp Thing
- The Thing from Another World
- Venom
- The Vision (2015)
- We Kill Monsters
- The X-Files Season 10
- Dead Space
- Frankenweenie
- Kite Liberator
- Lily C.A.T.
- Looney Tunes
- The "Magnetic Rose" segment of Memories, which is a classical Ghost Story.
- Resident Evil
- "Runaway Brain"
- Seoul Station
- 28 Days Later
- The Abominable Snowman
- Absurd (1981)
- Ad Astra (some segments)
- Alien
- Alien 2: On Earth
- Alien Cargo
- The Alien Factor
- Alien vs. Predator
- The second segment of All Hallows' Eve
- Alligator
- The Alligator People
- Altered States
- The Amazing Colossal Man
- A.M.I.: Artificial Machine Intelligence
- Anaconda
- Annihilation (2018)
- Antisocial
- Antiviral
- Apollo 18
- Apocalypse of the Dead
- Arachnia
- Arachnicide
- Arcade
- Army of Frankensteins
- The Arrival
- Assimilate
- The Astro-Zombies
- The Atomic Brain
- Attack of the 50 Foot Woman
- Attack of the Crab Monsters
- Attack of the Giant Leeches
- Attack of the Moon Zombies
- Attack of the Puppet People
- Await Further Instructions
- Bad Taste
- Banshee Chapter
- Bats
- The Bay
- Bedeviled
- The Beast from 20,000 Fathoms
- The Beast in Heat
- The Beast of Yucca Flats
- Before I Hang
- Beginning of the End
- Beyond the Black Rainbow
- Big Ass Spider!
- Birdemic
- Bite
- Black Butler
- Black Friday (2021)
- Black Sheep (2007)
- Black Wake
- Blackenstein
- The Blob (1958)
- The Blood Beast Terror
- Blood Freak
- Blood Machines
- Blood Waters of Dr. Z
- Blue Monkey
- Boa
- Body Melt
- The Borrower
- The Box
- The Brain (1988)
- Brain Damage
- The Brain from Planet Arous
- The Brain That Wouldn't Die
- Brainscan
- The Bride
- Bride of the Monster
- Brightburn
- The Brood
- Bug (1975)
- Captive Wild Woman
- The Car: Road to Revenge
- Carnosaur
- Carriers
- The Cave
- Cave Women on Mars
- The Cell
- Cemetery Gates
- Chernobyl Diaries
- Child's Play (2019)
- Chiller
- Chopping Mall
- C.H.U.D.
- Class of 1999
- Class of Nuke 'Em High
- Clonus
- Cloverfield
- A Cold Night's Death
- Color Out of Space (2020)
- Communion
- Contracted
- The Crawling Eye
- The Crawling Hand
- The Crazies (1973)
- The Crazies (2010)
- Creature from the Black Lagoon
- Creature with the Atom Brain
- The Creeping Terror
- Creepozoids
- Creepshownote
- Critters
- Crocodile
- Cube
- A Cure for Wellness
- The Curse
- The Curse of Frankenstein
- The Cyclops
- Dance of the Dead
- Danny Johnson Saves the World
- The Dark (1979)
- The Dark Side of the Moon (1990)
- Dark Skies
- The Day of the Triffids
- The Day the Earth Caught Fire
- Dead Air (2009)
- Dead and Deader
- Dead Heat
- Deadly Eyes
- Deadly Friend
- The Deadly Mantis
- The Deadly Spawn
- Dear God No!
- Death Factory
- Death Machine
- Death Warmed Up
- Decoys
- Deep Blue Sea
- Deep Rising
- DeepStar Six
- Demon Seed
- Demon with the Atomic Brain
- The Descent
- Destination: Outer Space
- The Devil Bat
- The Devil Commands
- The Devil-Doll
- Devil Fish
- Die, Monster, Die!
- Die You Zombie Bastards!
- Disturbing Behavior
- Doctor Blood's Coffin
- Doctor Jekyll and Sister Hyde
- Doctor X
- Donnie Darko
- Doom
- Dracula vs. Frankenstein
- Dr. Cyclops
- Dr. Jekyll and Mr. Hyde (1920)
- Dr. Jekyll and Mr. Hyde (1931)
- Dracula 3000
- Earth vs. the Spider
- Eden Log
- Eight Legged Freaks
- Empire of the Ants
- Endangered Species
- The Erotic Rites of Frankenstein
- Event Horizon
- Evolution (2015)
- eXistenZ
- Extraterrestrial (2014)
- The Eye Creatures
- Eyes Without a Face
- The Faculty
- FeardotCom
- Fido
- Fiend Without a Face
- Fire in the Sky
- Five
- The Flesh Eaters
- Flesh for Frankenstein
- The Fly (1958)
- The Fly (1986)
- The Food of the Gods
- Forbidden World
- Frankenfish
- Frankenhooker
- Frankenstein (1910)
- Frankenstein (1931)
- Frankenstein (2015)
- Frankenstein 1970
- Frankenstein Island
- Frankenstein's Army
- Frankenstein's Castle of Freaks
- The Frankenstein Theory
- The Freakmaker
- Friend of the World
- From Beyond
- Full Eclipse
- Galaxy of Terror
- Get Out (2017)
- Ghostbusters
- Ghost in the Machine
- Ghosts of Mars
- The Giant Claw
- The Giant Spider
- The Giant Spider Invasion
- God Told Me To
- Godzilla
- Goke, Body Snatcher from Hell
- Grabbers
- The Grapes of Death
- The Green Slime
- Guns of the Apocalypse
- The Happening
- Harbinger Down
- Hardware (1990)
- Hell of the Living Dead
- Hellraiser: Bloodline
- Hell's Highway
- Hidden
- The Hidden
- The Hideous Sun Demon
- High Life
- The Hive
- Hollow Man
- Honeymoon
- Horror Express
- The Horror of Party Beach
- Horrors of Spider Island
- Horrors of the Black Museum
- Horrors of War
- Horrorvision
- Hostile
- The Host (2006)
- The House by the Cemetery
- House of Dracula
- House of Ghosts
- Humanoids from the Deep
- Hungerford
- Hunter Prey
- I Am Legend
- I Eat Your Skin
- I Married a Monster from Outer Space
- I, Monster
- The Incredible Melting Man
- The Incredible Shrinking Man
- Indestructible Man
- Infini
- Inseminoid
- Invasion of the Bee Girls
- Invasion of the Body Snatchers
- Invaders from Mars (1986)
- Invasion of the Saucer Men
- The Invisible Man (1933)
- The Invisible Man (2020)
- The Invisible Ray
- The Island of Dr. Moreau (1977)
- The Island of Dr. Moreau (1996)
- Island of Lost Souls
- Island of Terror
- Island of the Fishmen
- Isolation
- It Came from Another World!
- It Came from Beneath the Sea
- It Came from Outer Space
- It Conquered the World
- It's Alive
- It! The Terror from Beyond Space
- Jack Frost (1997)
- Jason X
- Jesse James Meets Frankenstein's Daughter
- Journey to the Seventh Planet
- Kairo
- Killdozer!
- Killer Crocodile
- Killer Klowns from Outer Space
- The Killer Shrews
- King Cobra (1999)
- Kingdom of the Spiders
- Kiss Me Quick!
- Lady Frankenstein
- Lake Placid
- The Last Man on Earth
- The Late Night Double Feature
- Lavalantula
- The Lawnmower Man
- The Lazarus Effect
- The Leech Woman
- Legion (1998)
- Leprechaun 4: In Space
- Leviathan (1989)
- Life (2017)
- Lifeforce (1985)
- De Lift
- Link
- The Little Shop of Horrors
- The Living Dead at Manchester Morgue
- Lords of the Deep
- M3GAN
- The Mad Monster
- Maniac (1934)
- Man's Best Friend
- The Man They Could Not Hang
- The Man Who Changed His Mind
- The Man Who Could Cheat Death
- The Man Who Turned to Stone
- The Man with Nine Lives
- Mary Shelley's Frankenstein
- Matango
- Mayhem
- Maximum Overdrive
- Meatball Machine
- The Medusa Touch
- Mega Shark vs. Giant Octopus
- The Mihmiverse: The collective Shared Universe making up the movies of Christopher R. Mihm.
- Mimic
- Monkey Shines
- The Monolith Monsters
- Monster a-Go Go
- The Monster Maker
- The Monster of Phantom Lake
- The Monster That Challenged the World
- Morbius (2022)
- Morgan
- Mosquito
- Nazi Overlord
- The Neanderthal Man
- Nekrotronic
- The New Mutants
- Nightmare at Noon
- Night of the Big Heat
- Night of the Bloody Apes
- Night of the Comet
- Night of the Creeps
- Night of the Lepus
- Nightwish (1989)
- Nobody Sleeps in the Woods Tonight
- No One Will Save You
- Nope
- Office Uprising
- The Ωmega Man
- Outlander (2008)
- Overlord (2018)
- Pandorum
- Parasite Eve
- Patchwork
- Patrick
- Patrick Still Lives
- The Phantom Lake Kids In: The Unseen Invasion
- The Phantom Lake Kids In: The Beast Walks Among Us
- Phase IV
- Piranha
- Pitch Black
- Planet Of The Vampires (a.k.a. Terrore nello spazio)
- Plan 9 from Outer Space
- P.O.D.
- Possessor
- Predator
- Prince of Darkness
- The Projected Man
- Project: Metalbeast
- Prophecy
- Proteus
- Pulse
- Quarantine (2008)
- Queen of Blood
- Queen of Snakes
- A Quiet Place
- Rabid
- Rats: Night of Terror
- Re-Animator
- Red Planet
- The Relic
- Repo! The Genetic Opera
- Resident Evil:
- The Return (1980)
- Return of the Living Dead
- Robot Monster
- The Robot vs. the Aztec Mummy
- Robowar
- Rockabilly Zombie Weekend
- The Rocky Horror Picture Show
- Santo vs. la hija de Frankestein
- Saturn 3
- Scanners
- Scream and Scream Again
- Screamers
- Shakma
- Sharkenstein
- Shivers (1975)
- Shock Waves
- Shocking Dark
- Signs
- Silent Night, Deadly Night 5: The Toy Maker
- Silent Rage
- Skinwalker Ranch
- The Slime People
- Slither
- Slugs
- Society
- Species
- Spiders
- Splice
- Split Second (1992)
- Spontaneous Combustion
- Sputnik
- Squirm
- SS Doomtrooper
- Sssssss
- Starfish
- Starship Troopers 2: Hero of the Federation
- The Stone Tape
- Strange Behavior
- The Strange Case of Dr. Jekyll and Mr. Hyde (1968)
- Strange Invaders
- The Stuff
- The Suckling
- Sunshine
- Supernova
- Tarantula!
- Teenagers from Outer Space
- Tell Me How I Die
- Terminator
- Terror from Beneath the Earth
- Terror from the Year 5000
- TerrorVision
- Tetsuo: The Iron Man
- Them!
- These Are the Damned
- The Thing
- The Thing with Two Heads
- Thirst (1979)
- Thirst (2015)
- Tickles the Clown
- Ticks
- Time Walker
- The Tingler
- Tokyo Gore Police
- Track of the Moon Beast
- Train to Busan
- Triassic World
- Trog
- The Troll Hunter
- The Two Faces of Dr. Jekyll
- Under the Skin
- Underwater
- Uninvited (1988)
- Upgrade
- Us
- The Vampire
- The Vampire Bat
- Vampirella
- Venom (2018)
- Victor Frankenstein
- Videodrome
- Village of the Damned (1960)
- Village of the Damned (1995)
- The Vindicator
- Viral
- Virus Shark
- Virtuosity
- Virus
- The Visitor
- Vivarium
- The Void
- The Walking Dead (1936)
- Warning Sign
- The War of the Worlds (1953)
- War of the Worlds (2005)
- Warriors of Terra
- The Wasp Woman
- Weresquito: Nazi Hunter
- Werewolves of the Third Reich
- Westworld
- The Whisperer in Darkness
- Without Warning (1980)
- Wyrmwood
- X: The Man with the X-Ray Eyes
- X the Unknown
- Xtro
- Zombie Holocaust
- Zombieland
- Zombie Strippers!
- Zombies! Zombies! Zombies!
- Zombie Wars
- Zontar, the Thing from Venus
- Zygote
- The 5th Wave
- "The Age of Desire"
- All Your Ruins
- Black Destroyer
- Boojumverse
- The Brain Eaters
- Joseph Payne Brennan
- The Bride of Frankenstein: Pandora's Bride
- John Brosnan
- "Carnivorine"
- The Clone
- The Croning
- Cthulhu Armageddon by C.T. Phipps. Also a post-apocalypse Western.
- Several Cthulhu Mythos stories are within this genre, and the shared setting pretty much implies this for any of its horrors. H. P. Lovecraft's stories clearly within the subgenre include:
- Daikaiju Yuki, or at least the Mokwa trilogy that takes place within the same universe. The rest is more traditional science-fiction.
- The Dark Descent of Elizabeth Frankenstein, a retelling of Frankenstein through the perspective of the title character.
- Dark Warrior
- Dead Space
- The Draka, and in particular the sequel/spinoff Drakon.
- Dead Silence
- The Deep (Nick Cutter)
- The Descent
- Eat Them Alive
- Eden Green
- "The Elixir of Life (1903)"
- The Expanse is half this and half Space Opera. In the words of the author himself in the afterword of Leviathan Wakes:
"I've never written anything in my life that didn't at least blur the line into horror. If I wrote greeting cards, they'd probably have a squick factor."
- "The Fly"
- Fragment
- Frankenstein
- From the New World
- Geek Love
- Gone
- Human Resources (2018)
- The Hungry Plague
- Godzilla and Godzilla Raids Again
- Hyperspace Demons
- I Am Legend
- I Have No Mouth, and I Must Scream
- Into the Drowning Deep
- "It's a Good Life"
- James Herbert
- Jurassic Park (1990)
- Stephen King
- Cell
- Dreamcatcher
- Firestarter
- The Mist and "The Jaunt" from Skeleton Crew
- The Tommyknockers
- Kitty Cat Kill Sat
- Dean Koontz
- The Luminous Dead
- George R. R. Martin
- "Nightflyers"
- "Sandkings"
- The Melissa Allen Trilogy
- Necroscope
- Newsflesh
- Night of the Black Horror
- The Night's Dawn Trilogy
- Otherside Picnic
- The Outside
- Parasite Eve
- Past Doctor Adventures:
- Illegal Alien: A graphic depiction of Doctor Who's Cybermen.
- Matrix: A Doctor Who look at Jack the Ripper, featuring a mechanically processed, ethereal concentration of unadulterated evil.
- Peter Benchley's Creature
- The Relic
- Resident Evil
- Return of the Living
- Scorpion: Second Generation
- Shade's Children
- The Shadowspawn
- The Sister Verse and the Talons of Ruin
- Slime (1988)
- Small World (Tabitha King novel)
- Guy N. Smith
- Snow Shark
- The Southern Reach Trilogy
- Star Wars:
- The Stepford Wives
- Stinger
- The Strange Case of Dr. Jekyll and Mr. Hyde
- Thebe and the Angry Red Eye
- "The Things"
- "The Thought-Monster"
- The Thousand Eyes Of Night
- Titus Crow
- The Troop
- Tuskers
- Veniss Underground
- Peter Watts:
- Rifters Trilogy
- Blindsight starts out with a world where humanity is becoming obsolete in the face of cyborgs, hyper-intelligent A.I., and genetically reconstructed vampires with savant skills and no morals whatsoever. Then a team is sent out into the Oort cloud to make contact with aliens and find what appears to be simply a non-sentient biological probe at first, but later it dawns on them that the aliens aren't sentient but are much, much smarter than them. Plus, self-awareness is nothing but an anomaly that aliens see as a threat and vampires and A.I. are evolving away from.
- Echopraxia
- H. G. Wells:
- The War of the Worlds (1898)
- The Island of Doctor Moreau
- The Invisible Man (though it's more of a Psychological Thriller than horror)
- Who Goes There?
- "Window"
- Xeelee Sequence
- John Wyndham
- 1899
- All of Us Are Dead
- Black Mirror
- Doctor Who veers into this territory at times, "The Impossible Planet"/"The Satan Pit" and "Oxygen" being prime examples.
- The Expanse
- Fringe
- From
- Helix
- The Invisible Man (1984)
- The Last of Us (2023)
- Legion (2017)
- The Mist
- Nightflyers
- The Outer Limits (1963)
- The Outer Limits (1995)
- Parasyte: The Grey
- Resident Evil (2022)
- Sapphire and Steel
- Stranger Things
- Swamp Thing (2019)
- The Twilight Zone
- Ultra Q
- V (1983)
- V (2009)
- WandaVision mixes this up with Dom Com.
- War of the Worlds (1988)
- War of the Worlds (2019)
- The War of the Worlds (2019)
- The X-Files
- CthulhuTech
- Delta Green
- In Eclipse Phase, the Earth was taken over by A.I.s that made head-stealing drones, rampant Grey Goo swarms, and viruses that take over people's minds or mutate them into horrific monsters, all of which invoke Sanity checks on the behalf of players. Due to the gregarious use of Brain Uploading, the Player Characters can expect to be decapitated, slowly dissolved molecule by molecule, mind-controlled, mutated, and vaporized by their own employers to prevent whatever they caught from infecting what's left of civilization, repeatedly. Also, transhumanity has explored dozens of planets and found ruins of long-extinct alien races, but only one that is extant has been encountered.
- Mothership RPG
- SLA Industries
- Splicers focuses on the last members of humanity fighting a near-hopeless Robot War with horrifically disfiguring biotechnology and killer mutant animals.
- Warhammer 40,000. This game is the reason the word "grimdark" exists, make of that what you will.
- Zombicide: Invader
- 11:45 A Vivid Life
- 1213
- The Abyss: Incident at Europa
- Afterfall: Insanity
- Alien
- Among Us
- Antarctica 88
- Barotrauma
- Beacon (2018)
- Beyond: Two Souls
- BioShock
- Black Snow (Half-Life 2)
- BloodNet
- Bloody Zombies
- The Breach
- Buddy (2020)
- The Callisto Protocol
- Carrier
- Carrion
- Changed
- Chaos Heat
- Chicken Feet
- Chordosis
- Close to the Sun
- Close Your Eyes
- Code 7
- Condemned 2: Bloodshot
- The Council of Hanwell
- Creature Shock
- Cyberqueen
- Danganronpa Another Episode: Ultra Despair Girls
- Dark Seed
- Dead Effect
- Dead Space
- Deathless Hyperion
- Debris
- Deep Fear
- DERE.EXE
- Discover My Body
- Don't Get Spooked
- DOOM
- Dying Light
- Echo Night Beyond
- Endoparasitic
- End Roll
- Erie
- Enemy Zero
- The Evil Within
- Exit Limbo: Opening
- Extermination (2001)
- First Encounter Assault Recon
- The Forest
- Frostbite: Deadly Climate
- Garten of Banban
- Genetic Species
- Ghostbusters: The Video Game
- Ghostship
- GTFO
- GU-L
- Happy's Humble Burger Farm
- Hellpoint
- HEPH
- Hollow
- House of Ashes
- House of the Dead
- Hyperviolent
- Icescape
- I Have No Mouth, and I Must Scream
- Imscared
- Infested
- INPUT6
- Iron Helix
- Iron Lung
- The Last of Us
- Lethal Company
- Luna Abyss
- Manhunt 2
- Man of Medan (Please note that the reason why it belongs here is a massive spoiler, so potential viewers should proceed with caution while reading about it.)
- Marathon Infinity, the final game of the Marathon trilogy, veers into this from the previous two games' more general Sci-Fi.
- Mario '85
- Martian Gothic Unification
- Master Detective Archives: Rain Code
- Metro
- Midnight Ghost Hunt
- Moons of Madness
- Mothered
- Not Dying Today
- The Obscura Experiment
- ObsCure
- >OBSERVER_
- Outlast
- Parasite Eve
- Penumbra
- Phantasmagoria: A Puzzle of Flesh
- PO'ed
- Poppy Playtime
- Prey (2006)
- Prey (2017)
- RATUZ
- Resident Evil
- Resident Evil
- Resident Evil 2
- Resident Evil 3: Nemesis
- Resident Evil – Code: Veronica
- Resident Evil 0
- Resident Evil Gaiden
- Resident Evil: Gun Survivor
- Resident Evil 4
- Resident Evil: The Umbrella Chronicles
- Resident Evil 5
- Resident Evil: The Darkside Chronicles
- Resident Evil 6
- Resident Evil: Revelations
- Resident Evil: Revelations 2
- Umbrella Corps
- Resident Evil 7: Biohazard
- Resident Evil Village
- Resistance
- Ripout
- The Rocky Horror Show
- Sara is Missing
- Scorn
- SCP – Containment Breach
- Scars Above
- SIGNALIS
- Silent Debuggers
- SIMULACRA
- Smile
- Solarix
- SOMA
- Space Beast Terror Fright
- Space Yandere
- Spirits Of Xanadu
- SSTR
- Stasis
- Stasis: Bone Totem
- Stories Untold
- Subject
- Sukutte
- Syndrome
- System Shock
- Transference
- The Visitor
- The Voidness
- Water Womb World
- the white chamber
- Ghostbusters
- Godzilla: The Series
- Infinity Train
- Invader Zim
- LEGO Star Wars: Terrifying Tales
- Love, Death & Robots
- Monster Force: A Darker and Edgier take on Ghostbusters, featuring the Universal Horror monsters.
- Mutant League
- Scavengers' Reign
- Spiral Zone
- Super Robot Monkey Team Hyperforce Go!