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An Attack Animal is useful, but sometimes what nature provides is lacking. So you create your own attack animal, genetically engineering existing organisms or creating your own. Maybe add some cybernetics just to make it even stronger. Needless to say, this often backfires, proving that Genetic Engineering Is the New Nuke. Maybe this new organism would rather just be left alone, maybe it goes feral and becomes a dangerous monster, or maybe it works perfectly but those in charge of it are far from ethical.

A sub-trope of Living Weapon.


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Examples

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    Anime and Manga 
  • This is the true nature of the Evas in Neon Genesis Evangelion: giant mutated versions of the monsters they try to kill, all wrapped up in armor to make them look like giant robots. For bonus points, the armor is a Restraining Bolt because they are too good a killbeast.
  • In Yu Yu Hakusho, Corrupt Corporate Executive Tarukane bred a giant beast intended for use by the military from several of Earth's top predators. He asks Younger Toguro to demonstrate how tough he actually is by fighting it. Toguro says he'd rather not because he has a soft spot for animals, but he kills it easily.
  • The origin of Mewtwo in Pokémon. He was cloned from the DNA of the mythical and nigh-all-powerful Pokemon Mew by scientists for Giovanni, the boss of Team Rocket. Right after his birth Cloning Blues sets in, but Giovanni did manage to trick him for a while into serving as his attack animal.

     Comics 
  • One Batman/Alien crossover had the head of a weapons manufacturing company think it was a good idea to hybridize the Xenomorphs with Batman's Rogues Gallery (Joker, Poison Ivy...), with some kind of genetic manipulation so they wouldn't attack her, and Take Over the World. This backfired spectacularly when the truly gigantic (and awesome-looking) Alien/Killer Croc hybrid ran loose, having no reservations about killing her.
  • The giant squid monster in Watchmen. Curiously, its purpose was not to wage war but end it, by unifying all of humanity against the perceived common threat of psychic squid aliens.

     Film — Animated 
  • Lilo & Stitch: While cuter than most and he eventually has a Heel–Face Turn, Experiment 626 aka Stitch was created as an illegal genetic experiment serving as a virtually indestructible and super-strong Weapon of Mass Destruction. Many of the previous experiments are revealed to be designed with this trope in mind
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     Film — Live Action 
  • Alien:
    • An ongoing plot point throughout the entire Alien franchise is people (either a Mega-Corp like Weyland-Yutani, or Colonial Marines black-ops, or religious fanatics, to give some examples) trying to harness the Xenomorphs to turn them into bio-weapons. And never, ever learning that those things are a murderous blight upon any inhabited location that is unlucky enough to get them, no matter how many security measures are allegedly in place, and can never be controlled by anyone.
    • In Prometheus, we learn that the black goo was designed to make things into this trope in an effort to eliminate the human race because The Engineers were displeased with us as a species, ultimately leading to the creation of the Xenomorphs seen in Alien. And they inevitable lose control of them.
  • The Blob (1988): The Blob in this version is revealed to be the accidental result of an American military experiment conducted on a space satellite. Although the military scientists responsible didn't expect it, they're very pleased with the result and talk about deploying it against the Soviets. (In the original, it's just an alien who visits Earth to find food.)
  • The Deadly Spawn: The wormlike creatures are revealed in Word of God to be this for an invading alien race, Tyranid-style.
  • Gamera: During the Heisei era, Gamera and the Gyaos had this origin as opposing Atlantean bioweapons. Notably, Gamera is a rare benevolent example as he was created to destroy the Gyaos after they Turned Against Their Masters and is willing to protect humanity from other threats as well.
  • Jurassic Park: This trope comes into play as the corporate minds behind the in-universe Jurassic Park franchise decide that, since they can and have created numerous complex organisms more or less from scratch, there might be more money to be made from that in the arms industry than in vacation parks.
    • The Indominus rex in Jurassic World, the park's would-be star attraction, is revealed to have been created from the DNA of several dinosaurs — including Tyrannosaurus and raptors — as a living weapon capable of immense destruction. As it turns out, creating a highly intelligent, tyrannosaur-sized killing machine and then emotionally neglecting it into psychopathy does not make for a very easily controlled monster...
    • The Indoraptor in Jurassic World: Fallen Kingdom is a second take on the I. rex with most of the original flaws ironed out. It's smaller, although still quite large, and in order to be controllable it's conditioned to attack living creatures targeted by a sniper rifle's laser sight. It's still a barely controlled, viciously dangerous beast, although this is stated to be due to it still being a flawed prototype — its makers' intended next step is to create a new, improved batch based on the knowledge gained from their first try and to have Blue the raptor raise them, in order to create more mentally stable and easily controlled war monsters.
  • Mimic: The Judas Breed were originally designed as this against cockroaches. But then they managed to reproduce, evolve, and start hunting people...
  • In Tokyo Gore Police, the Engineers are sort of this, given their Lovecraftian Superpower of being able to sprout fleshy weapons from the various areas where their various bits are severed. Though, the first of the key-tumors that give them their abilities are technically of supernatural origin, they seem to be biologically copied and grown by the film's villain.
  • The unmade Godzilla (1994) gave Godzilla a similar origin to the abovementioned Gamera, where he was created by an ancient civilization from dinosaur DNA to combat hostile aliens.
  • In Pacific Rim, it's revealed that the Kaiju are actually manufactured (a scene shows one being knitted into existance by robotic arms) by aliens from another dimension to wipe out humanity as part of their plot to claim the Earth.
  • This is the usual origin of many monsters featured in a Syfy Channel Original Movie:
    • Sharktopus was developed as a weapon by the U.S. government, but they also made it psychotic so when its Restraining Bolt malfunctions, it starts actively hunting humans, even going inland in search of prey.
    • The snake in Python was also designed to be a weapon. But because the guys who designed it are idiots, they transport it with a minimal security complement, so it kills the crew and starts terrorizing a small town.
    • Boa Vs. Python plays with this by having two super-snakes developed, an "evil" python specifically bred for big game hunting, and a "good" boa which responds to human commands. When the python goes rogue, the boa has to fight it.

     Literature 
  • In Known Space, the laws of kzinti internal warfare restrict all combatants to muscle-powered weaponry in order to prevent nuclear holocaust. In Destiny's Forge, the Tzaatz clan attacks the ruling clan using bioengineered "rapsari" (battle-beasts are legal), armed with things like implanted Razor Floss or modified legs for carrying and operating catapults. Of course, there's an obscure law specifically banning rapsari, but unfortunately the Tzaatz's victory was too complete (everyone thought) to drop the hammer on them without creating a colossal power vacuum.
  • Into the Looking Glass: The space spiders (Organism 8198) were created as a weapon against the Dreen. Normally they eat as little as they can live on (eating anything but Dreen flesh actually causes them pain), but if they do have Dreen to eat, suddenly they become Explosive Breeder, Friendly Fireproof land piranhas. It's fully as awesome as it sounds.
  • These are the specialty of the Academy of Evil from Twig. The Empire that the Academy works for is constantly demanding newer and more exciting monsters for use in its wars of conquest, and over the years the Academy has developed all kinds of methods for making new Living Weapons, from Mix-and-Match Critters to mutagenic cocktails to genetic engineering.

     Live-Action TV 
  • Babylon 5:
    • The Keepers used by the Drakh — they were developed and bred with the sole purpose of bonding with a target host's nervous system and controlling their actions as directed by the Keeper's Drakh master, not directly but through sending intense pain signals through the host's body if they didn't comply.
    • The Vorlons introduced telepathic genes into various younger sentient races in an effort to developed weaponized beings that could jam Shadow vessels among other things. Lyta, who was a culmination of that long project, was described as "a weapon of mass destruction."
  • Buffy the Vampire Slayer: Season 4 introduces The Initiative, a secret government group studying demons for their potential use as weapons. They have created a Mix And Match Critter out of assorted demon parts; naturally, as soon as it is activated it turns on its creator and kills her, becoming the Big Bad of the season.
  • Farscape: The Peacekeepers endeavored to breed a variation of the sentient Leviathans that had weapons, with Moya's son Talyn being the prototype. (It was more than simply building a Living Ship per se, as it was at least implied that these normally gentle giants were naturally occurring, with Talyn's weapons being the result of some sort of genetic tampering from when the Peacekeepers commandeered his mother Moya.)
  • Stargate Atlantis: When the mutated wraith Michael starts pursuing his own agenda and becomes an Evilutionary Biologist, his first experiments to create an Ultimate Lifeform, namely by feeding humans to the parasitic Iratus bugs, ends up creating creatures closer to the bugs than to Wraith (who are themselves an intermediate state between humans and Iratus bugs). They look like large, black humanoids with exoskeletons and obey his commands, but he later replaces them with Hybrids, who are closer to human.

     Tabletop Games 
  • Warhammer 40,000: Some Dark Eldar Haemonculi specialize in this. Their creations, known as Grotesques, are hulking multilimbed Frankensteinian horrors able to go toe-to-toe against Tyranid melee organisms like Carnifexes, which happen to be something like Xenomorphs on steroids that can flip over tanks, and win.

     Video Games 
  • In AdventureQuest, the Drakels bred a couple types of creatures they call warbeasts. These were originally harmless herbivores that went extinct thousands of years ago, but the Drakels armored them and gave them energy weapon attacks.
  • In Civilization: Beyond Earth, factions following Harmony-related affinities can use genetic engineering to create mutated versions of the alien planet's native fauna, which might be used in tandem with human (or semi-human) troops
  • ClayFighter: Of all creations made by Dr. Kiln that usually turned against him, the only monster that stays loyal to him is Lockjaw Pooch, once Dr. Kiln's pet bull terrier that transformed into a killbeast thanks to the meteorite goop and stays as his bodyguard. Lockjaw Pooch appears in Sculptor's Cut as a selectable character, but he made an Early-Bird Cameo in the past game, 63 1/3 but reported as "dead".
  • Fallout: If a given species of monster isn't a Nuclear Nasty, it's almost always some kind of bioweapon engineered by the pre-War government that escaped and went feral after the nuclear apocalypse. Most of them are the result of the Forced Evolutionary Virus.
    • Super Mutants were designed to survive the wastelands better than humans in the event of a nuclear apocalypse. Humans exposed to the FEV transform into giant hulking brutes, almost always at the expense of their higher functions of intelligence, though focusing on staying educated during the process can avoid this. They're also aggressively violent at the drop of a hat, and ultimately sterile.
    • Chimeras are a writhing amalgamation of various human body parts with no forms of higher functions. They're the failed results of when humans don't transform into super mutants.
    • The deathchlaws were created from an unknown mixture of things (mostly the Jackson's Chameleon) to serve as ideal shock troops. The result was a species of ten-foot tall horned monsters capable of fighting multiple armed humans at once and have good odds of killing them all and with hide thick enough to shrug off small arms fire. Once they escaped and started breeding in the wild, this easily made them one of the most dangerous and powerful creatures in the wastelands.
    • The cazadores (wasp-like insects with the wingspan of a large bird of prey) and night stalkers (coyotes with the heads and tails of rattlesnakes) were both artificially created by Dr. Borous, one of the researchers at the Big MT scientific facility, largely for the hell of it. They were supposed to be sterile, but naturally enough they weren't and spread like wildfire.
    • In Fallout 3, it's revealed that the mole rats were created as a subtler take on this trope. The pre-War U.S. government engineered them to be the ultimate invasive species, with their extremely fast breeding, subterranean habits, indiscriminate diets and aggressive natures all being tailored to allow them to spread quickly and be extremely difficult to eradicate. The idea was to introduce them in Chinese territory to sabotage their war efforts and kill them off with a secret chemical kill switch once U.S. troops moved in. Of course, once the bombs fell and this knowledge was lost, their nature as a species tailored to go invasive with ease meant they thrived and quickly spread everywhere.
    • Floaters are giant worm-like creatures that inhabit the southwest wastes. They're the result of the U.S. Government exposing the FEV to flatworms.
  • In Final Fantasy XIII, tons of biomechanic duplicates of Gran Pulse animals and beasts have been produced and are deployed against the heroes by the Cocoon.
  • The Iconoclasts reveals that the Starworm is one of these once its head opens up to reveal that a birdman was piloting it all along.
  • Pokémon:
    • Mewtwo, an artificially-created Pokémon made from the DNA of Mew (the common ancestor to all Pokémon, and gifted with powerful psychic abilities) by a group of scientists funded by Team Rocket to create the ultimate battle Pokémon. It naturally broke loose and fled into the wild.
    • Genesect was created by Team Plasma as a biologically and cybernetically enhanced version of an ancient predator Pokémon. It was given a cannon on its back, but production was shut down by N due to finding it unnatural before it could reach its true potential.
    • In order to combat Ultra Beasts if they invade Alola, The Aether Foundation commissioned the creation of three Pokémon known as Type: Full. Inspired by the Mythical Pokémon, Arceus, they were created using the genetic material of Pokémon of all types as well as a piece of tech known as the RKS system, which allows Type: Full to freely change its type to be as flexible in battle as possible. However, all three Type: Full reacted badly to the RKS system and went berserk. With the project deemed a failure, they were then fitted with heavy helmets to control them, cryogenically frozen and their names were changed to Type: Null.
  • In Resident Evil, anything that isn't a zombie is almost certainly one of these. Umbrella specializes in using its viruses to manufacture all manner of bio-organic weapons, from the reptilian Hunters to the highly-intelligent Implacable Man Nemesis. Once the company was brought down for its role in several outbreaks, their bio-organic weapons began appearing on the black market and ending up in the hands of terrorist groups.

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