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Artificial Hybrid

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Most Half-Human Hybrids are created when members of two different species conceive a child together, or by descendants thereof. This trope applies to characters who at birth are fully one species (usually human), but somewhere down the road are turned (deliberately or by accident) into a hybrid between their original species and another one. May or may not occur through magical or scientific means, but in case the subject will often receive Hybrid Power as a direct result.


May overlap with Bio-Augmentation.


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    Anime & Manga 
  • The warrioresses in Claymore are created in this way. They are half human and half a yoma. And they are trained to kill pure yoma because they eat human guts.
  • Devilmen of Devilman are humans who fuse with teleporting demons. Some, like protagonist Akira, can switch between human and demon forms at will, but others are stuck with hybrid forms.
  • In Fullmetal Alchemist chimeras are produced by transmuting two individuals of different species together. Human chimeras are heavily illegal, which naturally meant that Father's cabal within the government created several of them as Super Soldiers.
  • While most hanyou are born in InuYasha as a child of a human and a youkai, there are also those who were once human. They offered a pact to the lower youkai. Their soul in exchange for a demonic body. Naraku was born this way, but the anime also shows two other unnaturally-created hanyou, namely Sara Asano and Tsubaki.
  • One Piece: The Zoan Devil Fruits let their eaters turn into hybrids of their original species and the species that the specific Devil Fruit gives. Chopper is a reindeer that ate the Human-Human Fruit and thus can turn partly humanoid, while Lucci is a human that ate the Cat-Cat Fruit.
  • Shinichi and Migi from Parasyte merge more and more until they are a mix of human and parasite.
  • Ken Kaneki from Tokyo Ghoul was a normal human being. After an accident that almost killed him, he is given organs from a ghoul and becomes a human-ghoul hybrid in the process.

    Card Games 
  • Magic: The Gathering:
    • This is how most of the sapient Simic hybrids came about. The Simic Combine is very big on shaping and altering one's physical form to suit one's needs, and as a result a great many Simic researchers and theoretically willing subjects who started out as regular elves or humans or merfolk end up becoming chimerical hybrids with the features of several species. A prime example is Prime Speaker Vannifar, who started out as an elf before turning herself into an elf/jellyfish hybrid.
    • Crossbreed Labs, in the non-canon set Unstable, explore this trope far more thoroughly than even the Simic do. Their goal is to create a society where everyone can be their true self, which they interpret to mean one where people can have the physical characteristics of whatever cretaure they desire. A typical Crossbreed Labs scientist is a chimera of a good half-dozen animals, any trace of their original self buried beneath their additions and modifications. Their leader, Dr. Julius Jumblemorph, brings this to its illogical extreme by having a rule that makes him every creature type in the game at once.

    Comic Books 
  • Carol Danvers (a.k.a the current Captain Marvel) was born a human woman, but eventually her DNA was altered in a way that turned her into a Kree/human hybrid. However, this was later retconned so that her mother was a Kree.
  • In Runaways, Victor Mancha is a cyborg created by Ultron. As he grows up, his body is designed to gradually become more organic, so that by the time he becomes an adult, he will be indistinguishable from a mutant and thus easily infiltrate the Avengers in order to betray them.
  • Downplayed with Spider-Man. Though Peter Parker is still considered a human, since the spider bite that gave him his powers his genetic code has a very small percentage of spider DNA.

    Fan Works 
  • In the Zootopia AU Ouroboros: The Endless Cycle, Judy becomes part fox after she is bitten by a venomous chimera and Nick saves her by transmuting the bitten arm and a few of her internal organs into copies of his own.

    Films — Live-Action 
  • Captain Marvel (2019) stays true to Carol's original backstory with her being a human who became a Kree hybrid via a blood transfusion.

  • Nnedi Okorafor's Binti: The Starfish Alien Meduse genetically engineer some of their traits into the title character so she can communicate with them (including through their Hive Mind). This gives her tentacular Alien Hair and some of the Meduse's emotions, the latter of which cause her some difficulty since they're much more prone to anger than she.
  • The first mendrites in the German SF series Maddrax were still created artificially, hybrids of humans and hydrites. The mendrites seen later in the plot have been naturally born.

    Live-Action TV 
  • At the end of the first season of Babylon 5, Minbari Ambassador Delenn uses a mysterious biotechnological device to enter a cocoon. At the beginning of the next season, she emerges from it to reveal that she's turned herself into a Minbari/Human hybrid, to be a living bridge between the species.
  • In Buffy the Vampire Slayer, the fourth season has Adam. He is a mix of humans, machines and demons, and was assembled in an underground secret lab.
    • Angel later shows Cordelia. She magically becomes a half-demon. As a result, she has powerful, magical powers, unlike the naturally born half-demons, but no super strength.
  • Doctor Who: In "Journey's End", a "biological metacrisis" turns Donna Noble half-Time Lord and also creates a half-human clone of the Doctor. Unfortunately for the new Artificial Hybrid, Donna's brain is still human enough that she can't handle the entirety of the Doctor's knowledge being copied into it, so he has to wipe her memories of him to save her life, although she is still a hybrid.
  • Played with in Star Trek: Voyager. At first it seems as though Seska is a Bajoran (an alien species) but then the doctor finds out that her DNA resembles that of a Cardassian (another alien species). She claims that she had a disease as a kid and got a blood transfusion from a Cardassian, but it turns out that she's lying and is fully Cardassian.
  • The supersoldiers in The X-Files have been artificially created. Before, they were ordinary humans.

    Tabletop Games 
  • Dungeons & Dragons has had numerous examples over the years:
    • Owlbears and Bulettes are both monsters that are famously created by wizards, mixing bears and giant owls in the case of the former and armadillos and snapping turtles in the case of the latter.
    • Many Half-(Whatever) templates in 3rd Edtion were the result of this, like the Half-Elemental.
    • The Guildmaster's Guide to Ravnica has the Simic Hybrid as a new player character race. They started out as ordinary humans, elves, or vedalken that the Simic Combine experimented on (allegedly with consent of the subject; allegedly). The experimentation gives them abilities like being able to breathe underwater, Combat Tentacles, or even spit acid.
    • Typically, driders — drow/spider centaurs — start out as simply dark elves, before having their legs replaced with a spider's torso.
  • Pathfinder:
    • Driders, like their D&D progenitors, begin life as dark elves before being turned into elf/spider hybrids. Similarly, oronci are orcs who were transformed into orc/centipede chimeras.
    • Areelu Vorlesh, the creator of the Worldwound, began life as a regular human witch but was transformed into a half-succubus through her service to the demons of the Abyss.

    Video Games 
  • Kraka-Tur from Arcanum is a former human who mutated himself into a Draconic Humanoid by killing Bellerogrim, the last dragon, and using his blood in a magic ritual.
  • Samus from the Metroid series was spliced with Chozo DNA (specified in the manga to have been from Grey Voice, one of her adoptive fathers) as a child so that she could better survive on the planet Zebes. During the opening of Metroid Fusion, she also gets injected with Metroid DNA to help her fight off an infection from the X Parasites. Exactly what percentage of her is still human is never specified.
  • Shin Megami Tensei is full of these.
  • Starcraft II: This is why the Tal'darim willingly serve the Big Bad Amon, as they want him to reshape their bodies into the monstrous(ly powerful) Zerg-Protoss hybrids. Once they learn that this is impossible and all hybrids have to be made from scratch, they defect and join you as the Token Evil Teammate.

    Western Animation 
  • Ben 10: Omniverse has the Rooters, a rogue Black Op Plumber branch consisting of former humans who became half-alien from experimenting on Kevin when he was in the Null Void. The Half-Human Hybrid aliens Helen, Manny, Alan, and Pierce from Ben 10: Alien Force are also apparently this, as they were normal humans experimented on by the Rooters and given Fake Memories to make them think they were natural-born hybrids.
  • Both Danny Phantom and his Arch-Enemy Vlad Plasmius were born human until they were each in accidents that transformed them into Human/Ghost hybrids.
  • The title characters of Rise of the Teenage Mutant Ninja Turtles eventually discover the Ooze didn't randomly mutate them into humanoids. Baron Draxum used it to combine their DNA with the mightiest human warrior he could find (Lou Jitsu, who later became Master Splinter).
  • Avatar Wan from The Legend of Korra was the first avatar. And he was created because when he was a human, he allied himself with Raava, and merged with her into a being.
  • In the last season of Trollhunters, Jim realizes he cannot win the day in his human form, and reluctantly agrees to undergo a process that will turn him into a human/troll hybrid. At first he enjoys his newfound strength and durability, but then suffers a Heroic Breakdown once he realizes he can't walk in the sun and must effectively abandon his human life forever.


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