This is when a character leaves/abandons someone that they were close to, maybe out of a obligation, personal reasons, or not by their own choice note like perhaps they died or were kidnapped for example. Maybe a character is a Living Emotional Crutch or a Morality Chain to them. Maybe they have implied romantic feelings for them. Maybe they were a pair of True Companions, or family.

In any case, the character who is abandoned for whatever reason goes crazy after the other leaves them. So this is more like the end result of a characters