In many works involving vampires or zombies, The Virus they infect victims with changes them into a form that is permanent. However, there are some stories which someone is capable of finding a cure for these otherwise irreversible conditions, despite if victims have lost important body parts required to survive.

These types of viruses usually exist within more family-friendly works in order to avoid any unnecessary violence and/or deaths for young viewers to see or works that do not desire to kill off any of the canon or significant characters who are afflicted.