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  • Juror #3 and Juror #10 to Juror #8 in 12 Angry Men.
  • 22 Bullets: Charly Mattei has Tony Zacchia, his Evil Former Friend who wants him killed so he can't get in the way of his drug business.
  • 48 Hrs.: Reggie Hammond has Albert Ganz, whom he had sold out to the authorities for a robbery they both committed.
  • 2020 Texas Gladiators: The Rangers have Catch Dog, a former member who was expelled for Attempted Rape and immediately joined the side of villainy, eventually killing a member who retired in good standing.
  • Abraxas, Guardian of the Universe has Secundus, his former partner who went evil to gain ultimate power.
  • Ray Finkle to Ace Ventura in Ace Ventura: Pet Detective.
  • The Adventures of Buckaroo Banzai Across the 8th Dimension: Buckaroo Banzai has Hanoi Xan, the criminal mastermind who killed his wife. Oddly enough for such a personal foe, he never appears in the film proper.
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  • The Adventures of Robin Hood: Robin Hood has Sir Guy of Gisborne, the thuggish knight who enforces Prince John's tyranny on Nottingham.
  • Ivan Korshunov to President James Marshall in Air Force One.
  • Alien: Ellen Ripley has the entire Xenomorph race, which she has vowed to destroy so they can't kill any more people.
  • Alice in Murderland: Alice Lewis has the Jabberwocky, AKA Kat Glass, whose mom murdered her mom and has pretended to be her best friend to continue the tradition.
  • Eve Harrington to Margo Channing and Addison DeWitt in All About Eve.
  • Richard Nixon and Donald Segretti to Bob Woodward and Carl Bernstein in All the President's Men.
  • Colonel Frank Fitts to Lester Burnham in American Beauty.
  • Frank Lucas to Detective Richie Roberts in American Gangster.
  • American Justice: Jack Justice has Sheriff Payden, a racist Dirty Cop who framed him for a murder one of his men committed.
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  • Wes Mantooth to Ron Burgundy in Anchorman: The Legend of Ron Burgundy.
  • Louis Cyphre to Harry Angel in Angel Heart.
  • Dean Vernon Wormer, Doug Neidermeyer, and Greg Marmalard to John "Bluto" Blutarsky, Eric "Otter" Stratton, Robert Hoover, Larry "Pinto" Kroger, Kent "Flounder" Dorfman, and Daniel "D-Day" Simpson Day, and Donald "Boon" Schoenstein in Animal House.
  • Janine Cody and Andrew Cody to Joshua Cody in Animal Kingdom.
  • Colonel Walter E. Kurtz to Captain Benjamin L. Willard in Apocalypse Now.
  • Zero Wolf to Jaguar Pawn in Apocalypto.
  • Asami Yamazaki to Shigeharu Aoyama in Audition.
  • Dr. Evil is the Arch Enemy of Austin Powers and his Evil Twin.
  • Colonel Miles Quaritch to Jake Sully and Neytiri in Avatar.
  • Juan Trippe to Howard Hughes in The Aviator.
  • Biff Tannen to Marty McFly, Dr. Emmett Brown, George McFly, and Lorraine McFly in Back to the Future.
    • It's later shown that the Tannens and McFlys have been and will be going at it for about 100 years. The rivalry presumably started with Seamus and Buford "Mad Dog" Tannen in 1885, and the last iteration we see are that Marty's children are still dealing with Griff Tannen in 2015.
  • The Barbarians: Kulchek and Gor have Kadar, the Evil Overlord who enslaved their entire tribe.
  • Catherine Tramell to Detective Nick Curran in Basic Instinct.
  • The Beastmaster has Maax, the Evil Sorcerer who mistakenly gave him animal powers while trying to kill him in infancy.
  • Betelgeuse to Adam Maitland, Barbara Maitland, Lydia Deetz, and Juno in Beetlejuice.
  • Victor Maitland to Axel Foley in Beverly Hills Cop.
  • John Fain to Jacob McCandles in Big Jake.
  • The Big Lebowski, Jesus Quintana, and Jackie Treehorn to the Jeffrey "the Dude" Lebowski and Walter Sobchak in The Big Lebowski.
  • Eddie Mars to Philip Marlowe in The Big Sleep.
  • Lo-Pan to Jack Burton in Big Trouble in Little China.
  • Black Belt Jones has Don Steffano, a crime boss who killed his master and wants to buy out his childhood dojo.
  • Black Butler: Shiori Genpo has her aunt, Lady Hanae Wakatsuki, who killed her parents and is currently plotting a terrorist attack on Japan.
  • Hjalmar Poelzig to Dr. Vitus Werdegast in The Black Cat.
  • Black Dynamite has Fiendish Dr. Wu, a Yellow Peril Diabolical Mastermind whom he's clashed with several times before the film, and turns out to be the one who killed his brother.
  • The Black Six have Thor, who murdered their leader's brother for dating a white girl.
  • Roy Batty to Rick Deckard in Blade Runner.
  • Hedley Lamarr to Sheriff Bart and the Waco Kid in Blazing Saddles.
  • Blood of Beasts: Freya has Sven, a warrior of her tribe who left her father to die and wants to make her marry him to rule the tribe.
  • Frank Booth to Dorothy Vallens and Jeffrey Beaumont in Blue Velvet.
  • Sheriff Frank Hamer has Bonnie and Clyde, a couple of bank robbers who humiliated him and whom he vows to capture or kill.
  • Carnegie to Eli in The Book of Eli.
  • Giuseppi "Papa Joe" Yakavetta to Connor MacManus, Murphy MacManus, and Il Duce in The Boondock Saints.
  • Jason Bourne from The Bourne Series had Robert Dewey.
  • King Edward I to William Wallace in Braveheart.
  • The Brotherhood of Death have Harold Turner, the Grand Cyclops of the local KKK, who uses his position as County Attorney to let his fellow Klansman terrorize the black community they banded together to protect.
  • Walter Chalmers and Johnny Ross to Frank Bullitt in Bullitt.
  • Although they do not appear in the film, Joe Lefors and E.H. Harriman are the archenemies of Butch Cassidy and the Sundance Kid.
  • Candyman to Helen Lyle.
  • The Candy Tangerine Man: The Black Baron has a pair of unnamed cops who will commit any crime to bring him down.
  • Max Cady to Sam Bowden in both versions of Cape Fear. In both versions, Max Cady seeks revenge against Bowden for getting him sent to prison by trying to harm Bowden's family.
  • Colonel Bishop to Captain Peter Blood in Captain Blood.
  • Margaret White, Billy Nolan, and Chris Hargensen to Carrie White in Carrie (1976).
  • Casablanca: Victor Laszlo has Major Heinrich Strasser, the Nazi official tasked with capturing him for his resistance activities.
  • Frank Abagnale Jr. to Carl Hanratty in Catch Me If You Can.
  • In Child's Play, Chucky is this to Andy Barclay and his family since he repeatedly harasses them. Cemented in Curse of Chucky when his next target, after the woman who put him away and her daughter, is Andy.
  • Noah Cross to Jake Gittes and Evelyn Mulwray in Chinatown.
  • Scut Farkus to Ralphie Parker in A Christmas Story.
  • Walter Parks Thatcher and Jim W. Gettys to Charles Foster Kane in Citizen Kane.
  • The Eccentric Millionaire to the Tramp in City Lights.
  • Zé Pequeno, Sandro Cenoura, and Knockout Ned to Buscapé in City of God.
  • Alex DeLarge to Frank Alexander in A Clockwork Orange.
  • Cold Sweat: Joe Martin has Katanga. They hated each other before Joe sold out his fellow prison escapees, and the only word Joe can use to describe Katanga is "virus."
  • Vincent to Max Durocher in Collateral.
  • Collateral Damage: Gordon Brewer has Claudio "El Lobo" Perrini, the terrorist leader who killed his family.
  • The Colony (2016): Lena has Paul Schaefer, the cult leader who's holding her boyfriend captive.
  • Marco and Don Luis Sandoval to Cataleya Restrepo in Colombiana.
  • In Commando, John Matrix had Bennet and Arius. Bennett was Matrix's unhinged former military subordinate until Matrix fired him, and Arius was a former dictator that Matrix deposed of in the past. The two of them teamed up to get revenge on Matrix by kidnapping Matrix's daughter, which sends Matrix on a Roaring Rampage of Revenge against them.
  • Cyrus Grissom to Cameron Poe in Con Air.
  • Conan the Barbarian has Thulsa Doom in Conan the Barbarian (1982), and Khalar Zym in Conan the Barbarian (2011).
  • Conquest: Illias and Mace have Ocron, a mad queen who believes they're destined to kill her.
  • The Captain to Luke Jackson in Cool Hand Luke.
  • Ricky Verona and El Huron to Chev Chelios in Crank
  • Richard Mason to Michael J. "Crocodile" Dundee and Sue Charlton in Crocodile Dundee.
  • Jade Fox to Li Mu Bai, Yu Shu Lien, and Jen Yu in Crouching Tiger, Hidden Dragon.
  • The Crow: Eric Draven has Top Dollar, the crime boss who had him and his fiance murdered.
  • Abigail Williams to John Proctor and Elizabeth Proctor in The Crucible.
  • Cure: Kenichi Takabe has Kunihiko Mamiya, a hypnotist who makes people murder their loved ones and loves playing mind games with him.
  • Darkman has Robert G. Durant, the thug who disfigured him.
  • Demolition Man: John Spartan has Simon Phoenix, a chaotic criminal who framed him for killing hostages and was then let out of cryofreeze to take him down for good.
  • Frank Costello and Colin Sullivan to Billy Costigan in The Departed.
  • El Mairachi has Moco in Film/El Mariachi, Bucho in Desperado, and General Emiliano Marquez in Once Upon a Time in Mexico.
    • Armando Barillo to Armando Barillo and Jorge Ramírez.
  • Mocata to the Duc de Richleau in The Devil Rides Out.
  • John Milton to Kevin Lomax in The Devil's Advocate.
  • Captain Spaulding, Otis B. Driftwood, and Baby to Sheriff Wydell in The Devil's Rejects.
  • Tony Wendice to Margot Mary Wendice, Mark Halliday, and Chief Inspector Hubbard in Dial M for Murder.
  • Hans Gruber to John McClane in Die Hard. Nakatomi Plaza is his defining moment, and Hans' brother Simon Gruber even appears seeking revenge. Colonel Stuart, Thomas Gabriel, Yuri Komarov, and Irina Komarov are this to a lesser extent.
  • Scorpio to Harry Callahan in Dirty Harry.
  • Koobus Venter and Piet Smith to Wikus van de Merwe and Christopher Johnson in District 9.
  • Django has Major Jackson, the Confederate guerrilla who killed his wife.
  • Stephen to Django, and Calvin Candie to Dr. King Schultz in Django Unchained.
  • Doll from Hell: Erika has the unnamed leader of a gang of Japanese Delinquents, who murdered her for witnessing one of their crimes, an act she tries to avenge from beyond the grave.
  • Frank and Jim Cunningham to Donnie Darko.
  • Don't Open Till Christmas: Chief Inspector Ian Harris has his insane brother Giles Harrison, who starts killing men dressed as Santa Claus to give his brother a challenging case.
  • Feraud is this in The Duellists. Deconstructed in that it makes both people unhappy and is a mostly-pointless grudge.
  • Jim and Esmeralda to Edward Scissorhands.
  • Elfie Hopkins: Cannibal Hunter has the Gammon family, a Cannibal Clan who live next door to her and end up killing her family.
  • Agent C.M. Kruger to Max Da Costa in Elysium.
  • Satan to Jericho Cane in End of Days.
  • Enemy Mine: Willis Davidge has Stubbs, an illegal mine owner who enslaved his adopted alien child.
  • Mr. Han to Lee in Enter the Dragon.
  • Nicolai Itchenko and Vladimir Pushkin to Robert McCall in The Equalizer.
  • The Duke to Snake Plissken in Escape from New York and Cuervo Jones in Escape from L.A..
  • Keys to E.T. and Elliott in E.T. the Extra-Terrestrial.
  • Evil Dead: Ash Williams has the Deadites, a horde of demonic zombies who spend the entire trilogy tormenting him and trying to destroy everything he loves.
  • Excalibur: King Arthur has Morgana le Fey, whose father was killed by his father and who intends to destroy Arthur's kingdom due to that.
  • Pazuzu to Father Lankester Merrin, Father Damien Karras, and Regan Theresa MacNeil in The Exorcist.
  • Jean Vilain, James Munroe, and Conrad Stonebanks to Barney Ross in The Expendables.
  • Castor Troy for Sean Archerin Face/Off.
  • Jerry Lundegaard, Carl Showalter, and Gaear Grimsrud to Marge Gunderson and Wade Gustafson in Fargo.
  • Deckard Shaw, Owen Shaw, Hernan Reyes, Johnny Tran, and Arturo Braga to Dominic Toretto and Brian O'Conner in The Fast and the Furious.
  • In Fatal Attraction, Dan Gallagher has Alex Forrest. Alex Forrest once had a brief affair with Dan, but she refused to accept the fact that Dan had a family to return her. As a result, Alex constantly stalks Dan, tries to entrap him in a permanent relationship with her, murders his family's pet rabbit, kidnaps his daughter Beth, and finally tries to murder Dan's wife, Beth.
  • Principal Edward Rooney to Ferris Bueller in Ferris Bueller's Day Off.
  • Colonel Nathan R. Jessep to Lieutenant Daniel Kaffee and Lieutenant Commander Jo Anne Galloway in A Few Good Men.
  • Jean-Baptiste Emanuel Zorg to Korben Dallas, Father Vito Cornelius, and Leeloo in The Fifth Element.
  • Tyler Durden is this and the Enemy Within to the Fight Club Narrator.
  • Fire with Fire: Jeremy Coleman has David Hagan, a neo-Nazi gang leader who spends the film pursuing him as a witness.
  • Alain Charnier to Jimmy "Popeye" Doyle in The French Connection.
  • In Friday the 13th, Jason Voorhees to Tommy Jarvis, the only person who killed Jason twice. His first encounter with Jason left him so traumatized that he was forced to spend several years in a mental institution. Tommy becomes so consumed with hatred against Jason that he digs up Jason's grave just so he can destroy Jason's corpse once and for all. Unfortunately, this results in Jason being resurrected as a Nigh-Invulnerable zombie.
  • Frostbiter: Wrath of the Wendigo: Sandy has the Wendigo, an Ancient Evil she is destined to defeat.
  • Sam Gerard and Fredrick Sykes to Dr. Richard Kimble in The Fugitive.
  • Gunnery Sergeant Hartman to James T. "Joker" Davis and Private Leonard 'Gomer Pyle' Lawrence in Full Metal Jacket.
  • General Dyer to Mahatma Gandhi in Gandhi.
  • In Gangs of New York, Amsterdam Vallon spent fifteen years plotting for revenge against Bill "The Butcher" Cutting for murdering his father during a gang war.
  • The Gingerdead Man: Sarah Leigh has Millard Findlemeyer, a Serial Killer she testified against who came back as a gingerbread man for revenge.
  • Martin Vanger to Lisbeth Salander in The Girl with the Dragon Tattoo.
  • Maximus Decimus Meridius had Emperor Commodus in Gladiator. They used to be friends until Commodus assassinated his own father, Emperor Marcus Aurelius, who was Maximus' father figure, declared Maximus a traitor, murdering Maximus' family, and forced Maximus to fight in the arena as a slave. Commodus in turn hated Maximus because his own family loved Maximus more than him, and because Maximus refused to acknowledge Commodus as Emperor.
  • Virgil Sollozzo and Emilio Barzini to Vito and Michael Corleone in The Godfather.
    • In Part II, Michael has Hyman Roth, and Vito has Francesco Ciccio.
  • Godzilla is the Arch Enemy of the Japanese Self-Defence Force as a whole during the films where he's the villain (or not). He also has his own recurring nemesis in King Ghidorah, who has battled him across eight films and four continuities, and whose gleeful malevolence provides a stark contrast with the Big G's more mindless rage. One could also make a case for Mechagodzilla, Godzilla's only enemy to rival Ghidorah for number of appearances (save for Mothra) and ability to hurt Godzilla (the Heisei version of Mechagodzilla in Godzilla vs. Mechagodzilla II is even stated to have been based on the recovered remains of Mecha-King Ghidorah from Godzilla vs. King Ghidorah, essentially making it a combination of Godzilla's two arch-enemies).
    • As far as Mothra goes, her arch-enemy is Ghidorah as well; she tolerates Godzilla's existence as long as he's not misbehaving too much, but when Ghidorah gets involved, she knows fully well that the whole planet she has sworn to protect is in danger. Epitomized by the Rebirth of Mothra trilogy, the first and third of which featured either Ghidorah or a close relative as the antagonist.
      • Godzilla: Final Wars made Gigan her arch-enemy instead so that the single coolest redesigned monster in the film could fight her during the climax while Godzilla dealt with the more plot-relevant antagonist—who was again, eventually revealed to be Ghidorah (this time in Kaiser form).
  • India Wilkes to Scarlett O'Hara, Rhett Butler, Ashley Wilkes, and Melanie Hamilton in Gone with the Wind.
  • Tommy DeVito and Jimmy Conway to Billy Batts in Goodfellas. And later, Henry Hill to Jimmy and Paul Cicero when Henry turns state evidence against his old crew and goes into Witness Protection.
  • Joseph McCarthy to Edward R. Murrow in Good Night, and Good Luck..
  • Mama Fratellli, Francis Fratelli, and Jake Fratelli to Michael "Mikey" Walsh, Brandon "Brand" Walsh, Lawrence "Chunk" Cohen, Clark "Mouth" Devereaux, Andrea "Andy" Carmichael, Stephanie "Stef" Steinbrenner, Richard "Data" Wang, and Lotney "Sloth" Fratelli in The Goonies.
  • Spider to Walt Kowalski, Thao Vang Lor, and Sue Lor in Gran Torino.
  • Grave of the Vampire: James Hollander has Charles Croydon, the vampire who raped his mother.
  • Von Luger to "Cooler King" Hilts in The Great Escape.
  • Wild Bill Wharton and Percy Wetmore to John Coffey and Paul Edgecomb in The Green Mile.
  • Grocer to Martin Q. Blank in Grosse Pointe Blank.
  • Gutterballs: Sarah has Steve, a rival bowling team leader who lead his team in gang-raping her. By extension, Steve is also the nemesis of the Bowling Ball Killer, who is her vengeful father.
  • In Halloween. no matter where Michael Myers goes, his psychiatrist Dr. Samuel Loomis will always be there to stop him. However, Michael's personal targets throughout the series are Laurie Strode and her daughter Jamie Lloyd.
  • Kenneth "Red" Parker, Jr. to John Hancock in Hancock.
  • Leslie Chow to Phil Wenneck, Stuart "Stu" Price, Alan Garner, and Doug Billings in The Hangover.
  • Shooter McGavin to Happy Gilmore.
  • Harakiri: Hanshiro Tsugomo has the Iyi clan, who forced his son-in-law to commit suicide.
  • Hawk the Slayer has Vultan, his villainous brother who killed their father.
  • Neil McCauley to Lt. Vincent Hanna in Heat.
    • Waingro to Neil. Waingro, a member of Neil's crew, turned an armed robbery into a triple homicide. With the help of Roger Van Zant and Van Zant's dragon Hugh Benny, Waingro forces another one of Neil's crew, Trejo, to rat Neil out to the cops, resulting in a deadly shootout between Neil's crew and Vincent and his subordinates. Waingro also raped and murdered Trejo's wife while beating Trejo to a pulp, leaving him in such a condition when Neil finds him, he is begging for death. After giving a Mercy Kill to Trejo (after Trejo tells him everything), Neil is hell-bent on killing Waingro, resulting in his own demise.
  • In Hellraiser, Pinhead makes repeated attempts to claim the soul of Kirsty Cotton. Kirsty also has her uncle, Frank Cotton, her stepmother Julia Cotton, and her husband Trevor Goodchild.
  • Hercules (2014): Hercules has King Eurystheus, who drugged him and then had Hercules' family murdered by trained wolves, while making him think that he'd done it.
  • He Knows You're Alone: Leo Gamble has Ray Carlton, who killed his fiance on their wedding day and has been pursued by him ever since.
  • The Kurgan to Connor MacLeod and Juan Sanchez Villa-Lobos Ramirez in Highlander.
  • The Hitcher: Jim Halsey has John Ryder, a homicidal hitchhiker who makes a game out of stalking him.
  • In the Film of the Book of The Hitchhiker's Guide to the Galaxy, Humma Kavula is this to Zaphod.
  • In The Hobbit trilogy, Azog is the main enemy of Thorin. whose grandfather Thror was killed by him in battle, where Thorin also cut off his hand. Following Thorin throughout the films and leading the Orcs to take Erebor at the Battle of the Five Armies, it is revealed that Azog is working for Sauron, but he is pursuing Thorin on his own incentive. They end up performing a Mutual Kill.
  • The Sanderson Sisters to Max Dennison, Alison, Dani Dennison, Thackery Binx, and Billy Butcherson in Hocus Pocus.
  • Harry Lime and Marv Merchants to Kevin McCallister in Home Alone.
  • Simon Skinner to Nicholas Angel in Hot Fuzz.
  • Mal Cobb to Dom Cobb in Inception.
  • I Come in Peace: Jack Caine has Victor Manning, the crime boss who killed his partner.
  • I'm Gonna Git You Sucka: Jack Spade has Mr. Big, the crime boss responsible for his brother's gold chain overdose.
  • Indiana Jones has Rene Belloq, a rival archaeologist willing to steal from Jones and collaborate with the Nazis to get the glory of discovery without doing the work.
  • Colonel Hans Landa to Lieutenant Aldo Raine, Shosanna Dreyfus, and the Basterds in Inglourious Basterds.
  • Innocent Blood: Maria has Sal the Shark, a Mafia don she accidentally turned into a vampire.
  • In In the Heat of the Night, Ralph Henshaw turns out to be the killer Virgil Tibbs spends the entire film looking for.
  • Mikhail Rostov to Matt Hunter in Invasion U.S.A. (1985).
  • V.I.K.I to Detective Del Spooner, Susan Calvin, and Sonny in I, Robot.
  • In It's a Wonderful Life, George Bailey has Mister Henry F. Potter. Potter is a Morally Bankrupt Banker who controls most of the town of Bedford Falls, with the exception of "Bulding & Loan", which which run by George Bailey. George Bailey is the only person preventing Potter from seizing total control over Bedford Falls, and when Bailey resists Potter's bribes, Potter tries to ruin him by framing him for embezzlement.
  • Jack Frost (1997): Sam Tiler has Jack Frost, a Serial Killer he captured who returned as a snowman for revenge.
  • Ordell Robbie to Jackie Brown.
  • The Kelly family as a whole has Jack-O, a demon sent by an Evil Sorcerer to avenge his execution by one of their own a century ago.
  • The Zec and Charlie to Jack Reacher.
  • As in the books, Ernst Stavro Blofeld/SPECTRE Number One was the archenemy of James Bond for most of the Sean Connery era films and George Lazenby's sole film. The endless legal disputes over the ownership of Thunderball, SPECTRE and Blofeld prevented the EON Productions film series from using Blofeld for over 40 years after Diamonds Are Forever, so Bond only confronted one-shot villains in that timespan. The legal feud was definitely solved in 2013, and Blofeld returned as Bond's overarching nemesis in Spectre in 2015.
  • The Shark to Sheriff Brody, Quint, and Matt Hooper in Jaws.
  • John Wick has Iosef Tarasov, who murdered his puppy for no reason.
  • Judge Dredd has Rico Dredd, his sadistic brother whom he personally arrested in the past, and is back for revenge.
  • Van Pelt to Alan Parrish in Jumanji.
  • Jurassic Park:
    • Dr. Alan Grant has the Spinosaurus, which spends the entirety of the third film stalking him and his group.
    • Ludlow to Ian Malcolm.
    • Dennis Nedry and Lewis Dodgson to John Hammond.
    • The Big One to Robert Muldoon.
  • Judge Henry T. Fleming to Arthur Kirkland in ...And Justice for All.
  • John Kreese, Johnny Lawrence, Chozen, Sato, Terry Silver, and Mike Barnes to Daniel LaRusso and Mr. Kesuke Miyagi in The Karate Kid.
  • Keoma has the other Shannon brothers, who have abused him his whole life out of sheer racism.
  • Johnny Rocco to Frank McCloud in Key Largo.
  • Beatrix Kiddo from Kill Bill: Bill, Elle Driver, O-Ren-Ishii, Budd, and Vernita Green. All five of them ended up on her hit list after they massacred her friends, murdered her fiance, and put her in a four-year coma as payback for deserting them. Beatrix also blames them for the death of her unborn child until she discovers she is still alive at the end of the second film.
    • Bill is more of her archenemy than any of the others though, both because he was The Leader and because his betrayal seems to have hurt her the most, hence the films' titles.
  • Wong Hoi to Ah Jong, Inspector Li Ying, and Wong Dung-Yu in The Killer.
  • Kindergarten Cop: Detective John Kimble has Cullen Crisp, a drug kingpin who he's been tracking for years and who eventually leads him to being a kindergarten teacher.
  • King Kong has Carl Denham, except in the MonsterVerse continuity, where his nemesis is the Skull Devil.
  • Tommy Udo to Nick Bianco, Assistant District Attorney Louis D'Angelo, and Nettie in Kiss of Death.
  • Kung Fury has Adolf Hitler, the Kung Fuhrer, who slaughtered his police station and seeks to steal his powers.
  • Jareth to Sarah Williams in Labyrinth.
  • Captain Dudley Smith to Detective Jack Vincennes, Bud White, and Ed Exley in L.A. Confidential.
  • Benedict and Tony Vivaldi to Jack Slater in Last Action Hero.
  • The Last House on the Left: The Cunninghams have Krug Stillo, the gang leader who raped and murdered their daughter and her best friend.
  • Idi Amin Dada to Nicholas Garrigan in The Last King of Scotland.
  • Magua to Hawkeye, Chingachgook, Uncas, Cora Munro, Alice Munro, Col. Edmund Munro, and Major Duncan Heyward in Last of the Mohicans. Magua has sworn vengeance against the Munro family for the death of his own family and Hawkeye, Chingachgook, Uncas and Major Heyward are protecting the women. Magua has sworn to cut out Col. Munro's heart and is as good as his word. The verdict at a debate in a Huron village leads to Magua taking Alice prisoner while Cora is to be burned at the stake, prompting Heyward's Heroic Sacrifice. Uncas, who loves Alice, impulsively pursues Magua, leading to his death as Magua cuts him down. Uncas's death prompts Chingachgook to kill Magua to avenge his son.
  • Colonel Bagley and Omura to Moritsugu Katsumoto and Nathan Algren in The Last Samurai.
  • The Last Witch Hunter: Kaulder has the Witch Queen, who killed his family and made him immortal.
  • General George Allenby, the Turkish Bey, and Mr. Dryden to T.E. Lawrence in Lawrence of Arabia.
  • Darkness to Jack o' the Green in Legend (1985).
  • Mister Joshua, Pieter Vorstedt, Jack Travis, Wah Sing Ku, Arjen Rudd, and General Peter McAllister to Martin Riggs and Roger Murtaugh in Lethal Weapon.
  • Louis Roulet to Mickey Haller and Maggie McPherson in The Lincoln Lawyer.
  • Caesar Enrico Bandello to Sergeant Flaherty in Little Caesar.
  • Audrey II and Orin Scrivello to Seymour Krelborn and Audrey in Little Shop of Horrors.
  • Rawley Wilkes to J.J. McQuade in Lone Wolf McQuade.
  • Timothy to Samantha Caine in The Long Kiss Goodnight.
  • David and Max to Michael Emerson in The Lost Boys.
  • Mr. Jang to Lucy, Professor Samuel Norman, and Pierre del Rio in Lucy.
  • Hans Beckert and Der Schränker to Inspector Karl Lohmann in M.
  • Rogelio Torrez and Luther Voz to Machete Cortez in Machete.
  • Mad Max
    • Max Rockatansky has the Toecutter, a criminal biker who killed his family.
    • Imperator Furiosa has Immortan Joe, the tyrant who kept her as a Sex Slave.
  • The Magnificent Seven (2016): Bartholomew Bogue to Sam Chisolm and Emma Cullen. Bogue murdered Emma's husband Matthew at the beginning of the film, prompting her to recruit Chisolm and the rest of the Seven to drive Bogue off. Chisolm accepted the job to get revenge on Bogue for the rape and lynching of Chisolm's mother and sisters (as well as lynching him).
  • Brigid O'Shaughnessy, Joel Cairo, Kasper Gutman, and Wilmer Cook to Sam Spade in The Maltese Falcon.
  • Mrs. Eleanor Shaw Iselin to Major Bennett Marco and Raymond Shaw in The Manchurian Candidate.
  • The Man from Nowhere: Cha Tae-sik has the Seok brothers, a duo of organ traffickers who abducted his only friend.
  • Liberty Valance to Tom Doniphon and Ransom Stoddard in The Man Who Shot Liberty Valance.
  • In Marathon Man Thomas "Babe" Levy develops a grudge against Dr. Christian Szell for torturing him to gain information that Babe new nothing about.
  • Masked Avengers: Lin Yung Chi and Gao Yi, his former Number Two who eventually left the organization because of his boss's crimes. Unlike most arch enemies, Gao prefers to lay low and doesn't directly oppose Lin until the end of the film.
  • Captain Esteban Pasquale to Zorro in the 1940 version The Mark of Zorro.
  • Don Rafael Montero to Don Diego de la Vega and Captain Harrison Love to Alejandro Murrieta in The Mask of Zorro.
    • Don Rafael was the corrupt governor of Mexico when Don Diego was Zorro, and in Diego's public life he was the husband of Esperanza, the woman Don Rafael loved. Rafael discovered that Diego was Zorro, and arrested him; Esperanza was killed in the raid, and Don Rafael took Diego's daughter Elena to raise as his own.
    • Alejandro's vendetta against Captain Harrison Love is built around the fact that Captain Love killed Alejandro's brother Joaquin and put his head on display in a jar that Love drinks from.
  • In The Matrix, Agent Smith to Neo.
  • Mean Girls: Janis Ian has Regina George, the Alpha Bitch who made her an outcast.
  • Boris the Animal to Agent J and Agent K in Men in Black 3.
  • Billie "The Blue Bear" Osterman to Maggie Fitzgerald in Million Dollar Baby.
  • Jim Phelps, Sean Ambrose, Owen Davian, Kurt Hendricks, Solomon Lane, and August Walker to Ethan Hunt and Luther Stickell in Mission: Impossible. Solomon Lane in particular as he is the only one who survived all his appearances.
  • Jim Taylor and Senator Joseph Paine to Jefferson Smith in Mr. Smith Goes to Washington.
  • Mulan: Rise of a Warrior: Mulan has Mengdu, The Evil Prince leading the armies against China.
  • High Priest Imhotep to Richard 'Rick' O'Connell, Evelyn 'Evy' Carnahan/O'Connell, Jonathan Carnahan, Ardeth Bay, and Alex O'Connell in The Mummy Trilogy.
  • Vincent Ludwig to Lieutenant Frank Drebin in The Naked Gun.
  • Uncle Rico Dynamite to Napoleon Dynamite.
    • Summer Wheatley to Pedro Sanchez.
  • Grant Frost to Danny Roman and Chris Sabian in The Negotiator.
  • Louis Bloom to Detective Fronteiri and Detective Lieberman in Nightcrawler.
  • In A Nightmare on Elm Street, Freddy Krueger had Nancy Thompson.
  • Reverend Harry Powell to John and Pearl Harper in The Night of the Hunter. Powell murdered the kids' mother, and spend the rest of the film trying to kill John and Pearl themselves.
  • Ninja: Casey Bowman has Masazuka, his Rival Turned Evil from his student days, who killed their master and wants to take over their ninja clan.
  • Phillip Vandamm to Roger O. Thornhill and Eve Kendall in North By Northwest.
  • Oblivion (1994): Zack Stone and Butou have Redeye, a reptilian outlaw who killed their father and entire family, respectively.
  • Lee Woo-jin to Oh Dae-su in Oldboy (2003), as he's the one responsible for him being locked up.
  • Kang Yeonsak to Mike Banning and President Benjamin Asher in Olympus Has Fallen.
  • Damien Thorn and Mrs. Baylock to Robert Thorn and Father Brennen in The Omen.
  • Harmonica and Frank in Once Upon a Time in the West. The former has been hunting the latter for decades to put an end to his horrible crimes and to avenge the death of his brother. Frank also has Cheyenne and Jill McBain, because Frank murdered Jill's new family and framed Cheyenne for their murders.
  • Johnny Friendly to Terry Malloy in On the Waterfront.
  • Captain Terrell to Josey Wales in The Outlaw Josey Wales.
  • Captain Vidal to Ofelia, Mercedes, Dr. Ferreiro, and Pedro in Pan's Labyrinth.
    • The Pale Man to Princess Moanna and the Faun.
  • Colonel Willaim Tavington to Benjamin Martin and Gabriel Martin in The Patriot.
  • Sean Miller to Jack Ryan in Patriot Games.
  • Field Marshal Erwin Rommel to General George S. Patton Jr. and Field Marshal Sir Bernard Law Montgomery in Patton.
  • Charles Wheeler to Andrew Beckett and Joe Miller in Philadelphia.
  • Pirates of the Caribbean:
    • Jack Sparrow and Hector Barbossa. Once both men have died at least once, the conflict between them becomes more of a friendly rivalry.
    • Commodore Norrington might also want to put himself in for consideration as Jack's Arch Enemy, though Jack seems to regard him as more of an obstacle and sometimes pawn.
    • Cutler Beckett may qualify, as he has been the source of much/most of Jack's problems in his life. When using Jack's compass, it points him towards Jack, and Jack guesses that what Beckett wants most in the world is to see Jack dead.
    • Davy Jones definitely qualifies, since he's hellbent on claiming Jack's soul. He could also count as one for Will Turner, whose father is one of the many cursed souls forced to work on Davy Jones' ship for hundreds of years.
  • Dr. Zaius to Colonel George Taylor, Cornelius, and Zira in Planet of the Apes (1968).
  • Staff Sergeant Bob Barnes to Sergeant Elias and Chris Taylor in Platoon.
  • Poltergeist: Carole Anne Freeling has Reverend Henry Kane, a spectral cult leader obsessed with using her as a conduit to return to Earth.
  • The Predator to Major Alan "Dutch" Schaefer in Predator.
  • In The Prestige, Alfred Borden and Robert Angier start as friendly rivals, but the two become arch-enemies when one loses a wife. By the end, one has lost his wife and his life, the other reaches a Pyrrhic Victory in besting his enemy but losing his brother and wife as well.
  • The Princess Bride:
    • Westley has Prince Humperdinck, an entitled noble who wants to force his beloved Princess Buttercup to marry him.
    • Inigo Montoya has Count Rogen, the sadistic torturer who murdered his father.
  • Norman Stansfield to Léon Montana and Mathilda Lando in The Professional.
  • Prom Night:
    • The original film: The killer/Alex Hammond to Wendy Richards, Nick McBride, Kelly Lynch, and Jude Cunningham. These four teens killed Robin Hammond years ago, and now this figure is out for revenge.
    • The remake: Richard Fenton to Donna Keppel and Detective Winn. Fenton developed a pedophilic love for Donna and murdered her family when they refused him, with Winn being the detective who put him away. Fenton escapes and comes to take another shot at Donna, with Winn trying to stop him before Fenton rapes or kills Donna.
  • Norman Bates to Lila Crane and Sam Loomis in Psycho.
  • Marsellus Wallace to Butch Coolidge in Pulp Fiction.
  • The Pumpkin Karver: Jonathan has Alec, whom he mistakenly killed in life and who torments him as a ghost.
  • The Punisher (2004): Frank Castle has Howard Saint, the mob boss who killed his entire family.
  • Quigley Down Under: Matthew Quigley has Elliot Marston, who got him to Australia under false pretenses and left him for dead when he protested his genocide campaign.
  • Jake LaMotta to Vikki LaMotta, Joey LaMotta, and Sugar Ray Robinson in Raging Bull.
  • Sheriff Will Teasle, Lieutenant Colonel Podovsky, Colonel Alexei Zaysen, Major Pa Tee Tint, and Hugo Martinez to John Rambo in Rambo.
  • Ran: Hidetora Ichimonji has Lady Kaede, whose parents he killed and who manipulates an entire war to bring him down.
  • Lars Thorwald to L.B. 'Jeff' Jefferies in Rear Window.
  • Mr. Blonde, Mr. White, Nice Guy Eddie Cabot, Mr. Pink, Joe Cabot, Mr. Blue, and Mr. Brown to Mr. Orange in Reservoir Dogs.
  • Samara Morgan to Rachel Keller, Noah Clay, and Aidan Keller in The Ring.
  • Nathan Burdette and Joe Burdette to Sheriff John T. Chance, Dude, Colorado Ryan, and Stumpy in Rio Bravo.
  • Robin Hood: Prince of Thieves has Sheriff George of Nottingham as usual, but with the added touch of the latter killing the former's father.
  • Archibald Cunningham to Rob Roy.
  • RoboCop has Clarence Boddicker, the crime boss who killed him as a human.
  • General Francis X. Hummel to John Patrick Mason and Stanley Goodspeed in The Rock.
  • Rocky Balboa has Apollo Creed, Clubber Lang, and Ivan Drago through the progression of the Rocky franchise. Ivan proves to be a special case. He lost his rival turned friend Apollo and his health turned especially bad after the fight forcing him into retirement. Even decades later when they meet again in Creed II Rocky considers Ivan Drago the worst thing to have ever happened to him.
  • Doctor Frank N'Furtur, Riff Raff, and Magenta to Janet Weiss, Brad Majors, and Rocky Horror in The Rocky Horror Picture Show.
  • Damon Killian to Ben Richards to The Running Man.
  • Ricky Tan, Juntao, and Kenji to Inspector Lee and Detective Carter in Rush Hour.
  • Ted Winter and Vasily Orlov to Evelyn Salt in Salt.
  • Savaged:
    • Zoe has Trey, leader of the gang of rednecks who raped and murdered her.
    • The Apache chief has Trey's grandfather, who killed him and his entire tribe a long time ago.
  • Steamboat Willie to Captain John H. Miller in Saving Private Ryan.
  • John "Jigsaw" Kramer from Saw had Eric Matthews and Jeff Denlon. Eric Matthews hates Jigsaw for kidnapping his son. Jeff Denlon hates Jigsaw for kidnapping his wife, and later allowing his subordinate, Amanda Young, to kill her.
  • Alejandro Sosa to Tony Montana in Scarface (1983).
  • Tony Camonte to Inspector Ben Guarino in Scarface (1932).
  • Scary or Die:
    • Emmett has the unnamed were-clown who gave him his monstrous curse.
    • Connie has Romeo, her abusive boyfriend who eventually murdered her.
  • Mr. Trask to Lieutenant Colonel Frank Slade and Charlie Simms in Scent of a Woman.
  • Ghostface to Sidney Prescott in Scream.
    • The first Ghostface, Billy Loomis, murdered Sydney's mother, Maureen, after she slept with Billy's father, ruining Billy's parents' marriage. Even after he gets his revenge on Maureen, Billy extends his vendetta to Sidney herself.
    • The second Ghostface, Debbie Salt, wants revenge against Sidney for killed her son, the aforementioned Billy Loomis.
    • The third Ghostface, Roman Bridger, is Sidney's half-brother, who hates Sydney because he was rejected by their shared mother. To escalate things, Roman was The Man Behind the Man for Billy and Stu.
    • The fourth Ghostface Jill Roberts, is Sydney's younger cousin, who wants to kill Sidney because she is envious of Sidney's fame.
  • Chief Cicatriz to Ethan Edwards and Martin Pawley in The Searchers.
  • John Doe to William Somerset and David Mills in Se7en.
  • Tom Keough, Captain McClain, and Commissioner Delaney to Frank Serpico in Serpico.
  • Don Logan to Gary "Gal" Dove, DeeDee Dove, Aitch, and Jackie in Sexy Beast.
  • Jack Wilson and Rufus Ryker to Shane and Joe Starrett in Shane.
  • David and Pete to Shaun and Ed in Shaun of the Dead.
  • The Shawshank Redemption: Andy Dufresne has Warden Samuel Norton, who systematically ruins his life after he tries to expose the prison's corruption.
  • Jack Torrance to Wendy Torrance, Danny Torrance, and Dick Hallorann in The Shining.
  • Shotgun Jones has Fletcher Rivington, the Amoral Attorney who killed his sister.
  • Sin City series:
    • Marv has Kevin, a Serial Killer who murdered a hooker he loved.
    • John Hartigan has Roark Junior, whom he mutilated for raping children and eventually escapes from prison to take down for good.
    • Dwight McCarthy has Ava Lord, his ex-girlfriend who tries to make him murder her husband.
    • Nancy Callahan has Senator Roark, who ruined her hero John Hartigan's life and drove him to suicide.
  • Skin Trade: Nick Cassidy has Viktor Dragovic, the human trafficker who killed his wife and sold his daughter.
  • Jamal Malik to Salim Malik in Slumdog Millionaire.
  • Sheriff Buford T. Justice to the Bandit in Smokey and the Bandit.
  • Eddie Kim to Neville Flynn and Sean Jones in Snakes on a Plane.
  • Brick Top to Mickey O'Neil in Snatch..
  • The Sons of Katie Elder have Morgan Hastings, who killed their mother and stole their farm.
  • Dark Helmet to Lone Starr in Spaceballs in Spaceballs.
  • Crassus to Spartacus in Spartacus.
  • Howard Payne to Jack Traven and Annie Porter in Speed.
  • Luke Plummer to the Ringo Kid in Stagecoach. Plummer and his two brothers murdered Ringo's father and brother, so Ringo breaks out of prison and hitches a ride on the titular stagecoach to avenge them.
  • Khan Noonien Singh to James T. Kirk and Spock in Star Trek II: The Wrath of Khan and Star Trek Into Darkness.
  • Star Wars:
    • The Jedi Order to the Sith Order for the entire franchise.
    • In the Prequel Trilogy, the Confederacy of Independent Systems/Separatist Alliance serves as this to the Galactic Republic. For a character-specific example, Darth Maul was an Arch Enemy for Qui-Gon Jinn and Obi-Wan Kenobi. Likewise, Count Dooku became an Arch Enemy for Anakin Skywalker after cutting off one of his hands.
    • The Rebel Alliance to the Galactic Empire in the Original Trilogy. Furthermore, Luke Skywalker was the archnemesis for his father Darth Vader until Return of the Jedi where Sheev Palpatine/Darth Sidious takes up this role.
    • The Resistance to the First Order in the Sequel trilogy. Additionally, Rey becomes one for Ben Solo/Kylo Ren at least until The Rise of Skywalker where Emperor Palpatine once again fulfills this role.
  • Stanley Kowalksi to Blanche DuBois and Stella Kowalski in A Streetcar Named Desire.
  • Marko, Murad, Stuart St. John, and Oleg Malankov to Brian Mills in the Taken series.
  • Travis Bickle spends much of the film preparing to assassinate Senator Charles Palantine in Taxi Driver.
  • Teenagers from Outer Space: Derek has Thor, a fellow alien whom he butted heads with long before he got to Earth, and who is sent to capture him when he goes rogue.
  • Rameses II to Moses in The Ten Commandments. Or is it GOD to Rameses?
  • SkyNet to John Connor in Terminator. Every installment has it sending a Killer Robot into the past (T-800, T-1000, T-X, and the T-RIP T-800) to kill John before he can grow up and lead the human race in the war against the machines.
  • Leatherface and his family to Sally Hardesty and Lieutenant "Lefty" Enright in The Texas Chainsaw Massacre.
  • Detective Hal Slocumb to Louise Elizabeth Sawyer and Thelma Yvonne Dickinson in Thelma & Louise.
  • Daniel Plainview to H.W. Plainview and Eli Sunday in There Will Be Blood.
  • The Thing to R.J. MacReady in The Thing (1982).
  • Herbert MacCaulay to Nick Charles and Nora Charles in The Thin Man.
  • Harry Lime to Holly Martins in The Third Man.
  • This Is the End:
  • Caledon Hockley to Jack Dawson and Rose DeWitt Bukater in Titanic (1997).
  • To Kill a Mockingbird: Atticus Finch has Bob Ewell, who framed his innocent client for beating his daughter, and decides to kill his children after Finch makes him look like a fool in open court.
  • Tokyo Gore Police: Ruka has the Chief of Police, who killed her father to privatize the police force.
  • Johnny Ringo and Curly Bill to Wyatt Earp and Doc Holiday in Tombstone.
  • Lori Quaid, Vilos Cohaagen, Richter, and Benny, to Douglas Quaid and Melina in Total Recall (1990).
  • Police Captain Hank Quinlan to Mike Vargas, Susan Vargas, and Police Sergeant Pete Menzies in Touch of Evil.
  • The Town That Dreaded Sundown: Captain JD Ramirez has the Phantom Killer, a Serial Killer he was called into Texarkana to stop, and whose escape from capture haunts him for the rest of his life.
  • The Toxic Avenger has Bozo, the violent thug who dunked him in the waste in the first place.
  • Randolph Duke and Mortimer Duke to Louis Winthorpe III and Billy Ray Valentine in Trading Places.
  • Officer Jake Hoyt and Detective Alonzo Harris gradually become enemies throughout the progression of Training Day.
  • Trancers: Jack Deth has Martin Whistler, a mind-controlling criminal whom he regularly thwarted in the past, giving them a mutual hatred.
  • Gianni Chellini, Johnson, and Wall Street to Frank Martin in The Transporter.
  • Tran to Kirk Lazarus and Tugg Speedman in Tropic Thunder.
  • Lucky Ned Pepper to Rooster Cogburn, and Tom Chaney to Mattie Ross in True Grit.
  • Salim Abu Aziz to Harry Tasker in True Lies.
  • Drexl Spivey, Vincenzo Coccotti, and Virgil to Clarence Worley and Alabama Whitman in True Romance.
  • Since Bruce Willis's character, David Dunn, turns out to be a comic book superhero in Unbreakable, it only stands to reason that he'd have an arch-enemy. Elijah Price, who is right under his nose.
  • William Stranix and Commander Krill to Casey Ryback in Under Siege.
  • Viktor to Selene, Michael Corvin, and Lucian in Underworld.
  • Little Bill Daggett to William Munny in Unforgiven.
  • Al Capone to Eliot Ness in The Untouchables (1987).
  • V for Vendetta: V has the entire Norsefire party, who experimented on him and has dropped the country into fascism.
  • Valentine: Dorothy Wheeler to Jeremy Melton/Adam Carr. Dorothy framed Jeremy for sexually assaulting her in middle school, corroborated by her friends Paige, Lily, and Shelley.
  • Versus: Prisoner KSC2-303 has "The Man," a necromancer he's destined to battle each time he reincarnates.
  • Judy Barton and Gavin Elster to John "Scottie" Ferguson in Vertigo.
  • The Virgin Spring: Tore has the two shepherds who raped and murdered his daughter.
  • Gordon Gekko to Bud Fox in Wall Street. Bud Fox was Gekko's former protege, until Gekko manipulates Fox into helping him bankrupt his father's company.
  • David Allen Griffin to Joel Campbell in The Watcher.
  • Baby Jane Hudson to Blanche Hudson in Whatever Happened To Baby Jane?.
  • Cody Jarrett to Hank Fallon in White Heat.
  • Emil Stenz, Eli Raphelson, and Martin Walker to James Cale, James William Sawyer, and Carol Finnerty in White House Down.
  • The Witches Hammer: Rebecca has Madeline Renoir, who ordered everybody else in her Creature-Hunter Organization massacred.
  • In Without a Clue, Professor Moriarty and... wait for it... Dr. Watson. Moriarty is the only one smart enough to have figured out that the man called "Sherlock Holmes" is just a front for Watson, who's the real Great Detective.
  • The Wicked Witch of the West to Dorothy Gale, the Wizard of Oz, the Scarecrow, the Tin Man, the Cowardly Lion, and Glinda in The Wizard of Oz.
  • Mick Taylor to Liz Hunter, Kristy Earl, and Men Mitchell in Wolf Creek.
  • Wolfman: The Glasgow family has Reverend Leonard, a Satanist priest sent to torment them after a member reneges on a Deal with the Devil.
  • The Wolf Man to Sir John Talbot, Dr. Lloyd, Colonel Paul Montford, and Maleva to The Wolf Man (1941).
  • Jordon Belfort to Patrick Denham in The Wolf of Wall Street.
  • X-Men Film Series
    • Pyro to Bobby, of the We Used to Be Friends variety.
    • Victor Creed to Wolverine in X-Men Origins: Wolverine, although the series as a whole places considerably more focus on the animosity between Wolverine and William Stryker.
    • Magneto (Erik Lehnsherr) to Charles Xavier. In this case, it's an example of We Used to Be Friends.
    • Deadpool and Ajax.
  • Youth of the Beast: Jo Mizuno has Nomoto Testuo, the yakuza boss who killed his partner.
  • Zombie Cop: Robert Gill has Dr. Death, the voodoo priest who zombified him.

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