WMG / Death Battle One On One Match Suggestions A To F

Death Battle suggestions for one-on-one matches with a common link, sorted from A-F:

• Main Page
• Backstories
• Combatants Relationships
• Recurring Trends
• Song Titles
• Suggestions
  • One-on-one with a common theme
    • A-F
    • G-J
    • K-M
    • N-Z
  • Groups of combatants with a common theme
  • Battle Royales/Team Battles
  • Joke Suggestions/Bad Ideas for a DB
  • Returning Combatants
    • Seasons 1-5
    • Seasons 6-10
    • Seasons 11-15
  • Original Tracks

A few things to keep in mind:

• Remember that they should have at least some common factor. Even the Starscream vs. Rainbow Dash had one; both being popular high flyers in their toylines in Hasbro. Also, no fanon interpretations of characters.
• No creepypasta. They have too many unknowns to be qualified combatants, and Death Battle is known for showing their research.
• Characters who run on the Rule of Funny are generally frowned upon. With no established limits, any scientific limits would be random. However, this doesn't really apply if that is the entire point; if you have a "just for fun" type match up, put it in the Jokes Battles folder.
• No Memetic Badasses after Chuck Norris and Segata Sanshiro (that match-up's enough, thanks!). The fun of the meme is kind of ruined when the show reveals and proves that they're not nearly as badass as all the jokes and facts say. And besides, the aforementioned match ended in an apocalyptic draw. ^note  Just to clarify, characters with memetic status are allowed to be listed here, but they shouldn’t be listed because of memes. For example, Shaggy can be listed here, but his Ultra Instinct abilities and other non-canonical feats must be completely ignored.
• If you see several characters carrying the same consistent theme in this page, be sure to move them here.

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A

• 2B vs...
  • Stella / Black★Rock Shooter (Black-clothed anime videogame girls who are near emotionless living weapons [2B being a Android and Stella being a clone] created in order to fight in a war against an alien menace who has nearly killed all of humanity [the Machine Lifeforms and the Aliens], alongside other people [9S and Yorha, and Nana with the remaining humans]. During the course of the game, they do gain a bit more emotion and also manage to kill off the leaders of the aliens [Adam and Eve/White Rock Shooter and the Seven Apostles] tho, it barely matters in the end, since all of humanity ends up dead anyways [The 10 remaining humans die halfway through and Humanity was already dead before Nier: Automata] They also fought off against a similar looking villain [2P and White Rock Shooter])
  • Rapi (Two androids voiced by Yui Ishikawa created to fight in post-apocalyptic world with a militaristic attitise while little by little questioning their existence, with their very existence later getting move to a different body [2B's memories got taken by A2 and Rapi's body was temporarily taken by Red Hood]. They also have officially crossover in the past where these similarities got lampshaped)
• 2D vs. Tom (Deadpan Snarkers that are part of a Four-Man Band that was down a member at one point, and are known In-Universe for having Black Bead Eyes)
• A2 vs. Eula Lawrence (Traitors to organizations/family getting shunned by them and forced to lived on their own, they harbor their feelings within and barely open to others, both have a theme about their sins of their past while trying to attone for them by not let those atrocities)
• Accelerator vs...
  • Sebastian Shaw (Masters of No-Sell)
  • Add (White-haired, mentally-unstable geniuses that can manipulate the elements, who first were villains but later became heroes, and have similar designs)
• Achilles vs. Cú Chulainn (Legendary mythological spearmen capable of astounding feats, and are nigh-unkillable, capable of surviving wounds that normally would kill a normal human)
• Achilles (Fate) vs...
  • Kagura Mutsuki (Laid back care free indiviuals who're emphatic towards people and are total lady killers, are highly respected and well known individuals [Achilles known for as the "Hero of Troy" and Kagura's known as the "Black Knight"], have rivalries throughout their series that focus on power and speed [Chiron and Atalanta for Achilles, while for Kagura are Bang and Azrael], they'd go to question the organization/team own goals [for Achilles he questions his own goals and what he wanted during the time he spent on the Red Faction while Kagura questioned about the NOL and their goals], and both would eventually defect)
  • Chosokabe Motochika (Two warriors based on real mythos that deal with waves of enemies on their own, establish rivalries with subsequent opponents [Atalanta and Chiron for Achilles, Date Masamune for Chosokabe in the anime], are capable of taking several hits point blank, have laid back personalities yet they're always eager to fight, and are well know for the use of vehicles [Achilles' chariot and Chosokabe's boat])
• Acnologia vs...
  • Alduin (Extremely powerful and feared black dragons)
  • Deathwing (Extremely powerful, ancient, and destructive dragons who betrayed their kind by becoming evil and seek to destroy all life)
  • Eternatus (Titanic, legendary, evil, cataclysmically powerful dragons with reality-bending and ability nullifying powers)
  • Fatalis (Extremely dangerous and widely feared dragons who seek to destroy mankind)
  • Kaido (Powerful antagonists from popular manga/anime series who are referred to as kings and can transform into dragons)
  • King Ghidorah (Extremely powerful and feared dragons associated with the apocalypse)
  • Seath (Villainous dragons who desire the extinction of their race after being betrayed by them)
  • Seiros/Rhea (Legendary, vengeful dragons who can shift into humanoid forms)
• Adam vs...
  • Asura (Extremely powerful, shirtless, fist-fighting fathers from mythology inspired series who fight gods for the sake of their children and humanity as a whole, have a motif centered around their eyes, fight the Top God of their respective series, and die at the end of the fight, still standing and with a smile on their face)
  • Jin Mori (Strong fighters who are based around a mythology setting in a tournament scenario)
• Adam Smasher vs...
  • Metallo (Full-Conversion Cyborgs with SkeleBot 9000-looking heads with ties to Warner Bros. [in the case of Adam Smasher, Warner Bros. Interactive Entertainment published Cyberpunk 2077 in the US])
  • Muscular (Ruthless, brutish antagonists who have augmented bodies in a sense [Adam through cybernetics, Muscular through a natural superpower] who adore causing violence and bloodshed and are responsible for the deaths of a pair of heroes prior to the main events of their series)
  • Sundowner (Violent, Ax-Crazy antagonists who were once Sociopathic Soldiers before becoming mercenaries, later became mechanically-modified enforcers of powerful organizations, and love nothing more than causing death and destruction)
  • Tarkus (Brutish, antagonists who serve higher powers, were modified in a sense from their original human forms with conflicting methods [Adam thorough cybernetic augmentations, Tarkus through vampirism], adore causing violence and bloodshed, and kill the protagonist's mentor figure [Silverhand for Adam, Zeppeli for Tarkus])
• Adam Taurus vs...
  • Gideon Graves (Powerful antagonists who seek revenge against their ex-girlfriends)
  • Jetstream Sam (Samurai-esque swordsmen who can launch their red-bladed swords from their sheathes)
  • Ramattra (Revolutionaries who fight for their oppressed race)
  • Rin Okumura (Horned swordsmen who are rejected by the worlds they live in due to their species)
  • Sho Minazuki (Sword-wielding misanthropes with a red-and-black color scheme, including red hair, have scars as a result of their tragic childhoods, desire to take revenge against humanity for their mistreatment, and are obsessed with a major protagonist of their work [Blake for Adam, Yu for Sho])
  • Tighten (Superpowered, self-centered Fiery Redheads who feel entitled to have Blake and Roxanne respectively)
  • Zato-1 (Masked, mentally-unstable assassins who were the former love interests of heroes that they then tried to kill even coming back from the dead after they originally killed them who became the leader of their organization, were subjected to inhumane treatment, and psychologically abused other heroes, with Adam Taurus never redeeming himself while Zato-1 did)
• Aether/Lumine vs...
  • Byleth (Sword-wielding protagonists who team up with a large cast of characters [including a right-hand, female, spiritual entity, with Sothis for the former and Paimon for the latter] from recent, popular fantasy games who have powerful magical abilities sealed within them)
  • Gran/Djeeta (Sword-wielding protagonists from fantasy-themed gacha mobile games)
  • Nier (Both lived in destroyed worlds, are quite stoic and don't shy away from help anyone in need, can be quite sassy at times due to the amount of work put at them [Aether/Lumine were told when young to use compassion kindness and nobility in order to garner more companions, Nier as a young man is compasionate and determined to cure his sisters illness of the black scrawl going around taking jobs to help people to reach that goal], were separated from there beloved siblings by an unknown beig and spend years trying to find them, both'll reunite with their siblings but also lose them [Nier found the Shadowlords Castle and fought him either rescuing Yonah or losing her in the fight depending on the route ending, and Aether/Lumine meeting their twin but learns that they're currently enemies and wants the other to travel all over Teyvat to see if their views align], are accompanied by a mysterious flying companion who they can talk about their worries and help them journey around the world, both have a wide arsenal of weaponry, creating and enhancing their abilities [Aether/Lumine being able to manipulate elements and Nier use maso particles to manipulate space and], both their lifes were affected due to great cataclysmic events, and both their flying companion [Paimon and Weiss] are affraid of ghosts)
• Aganos vs. Golurk (Gentle Giant golems created by ancient civilizations to serve as guardians for them who now wander the planet without a master)
• Agatha Trunchbull vs. Dolores Umbridge (Sadist Teachers who are masters at creating Death Traps designed to prolong a kid's suffering)
• Agent 3 / Captain vs...
  • Horse (Enhanced animal soldiers)
  • Blob (both are unwitting new recruits to heroic organizations that use their wit, athleticism, bravery, and bodily fluids as Art Attackers. Both quickly rise up through the ranks to become the face of revolution against totalitarian regimes [the Octarians and INKT, respectively], and eventually inspiring the oppressed citizens to join their cause.
• Agent 47 vs...
  • Aiden Pearce (Stealthy, resourceful anti-heroes who're quite proficient with firearms and close-quarters combat)
  • Ezio Auditore (Master assassins)
  • Golgo 13 (Elite Consummate Professional Killers)
  • Harry Hart (Powerful, sharpshooting protagonists who work for powerful organizations and are the greatest figure from a line of men their caliber, with the former being an assassin while the latter is a secret agent)
  • The Spy (Expert assassins who use stealth to their advantage)
• Agent Smith vs...
  • Controller X (Overly dramatic villains who wear sunglasses, betrayed their master, and have an army of sorts [with Agent Smith having his clones while Controller X has his kaiju])
  • Diaboromon (Sentient programs which become apocalyptic threats and have the ability to copy themselves infinitely)
• Ahri vs...
  • Delphox (Foxes with psychic abilities, with the latter is inspired by eastern magic and made by a western video game studio while the latter is inspired by western magic and made by an eastern video game studio)
  • Kamen Rider Genm (Morally-dubious characters who seek to become powerful through deceiving others)
  • Ninetales (A battle between two of the most iconic nine-tailed foxes in video games)
  • Tamamo-no-Mae (Kumiho vs. Kitsune; both are mystical beings that are in constant fear of the possibility of damaging someone they could hold dear as the first man they loved died many years ago, can enhance their speed and agility, can charm any person [though Tamamo rather not], fight using a floating construct [an orb for Ahri and a magic mirror for Tamamo], like dressing as Joshikouseis, and have manipulations over souls [Ahri can suck souls and Tamamo can bring back the dead but both of them avoid using these abilities])
• Ahsoka Tano vs...
  • 2B (Once young and courageous warriors who worked for a peace-keeping organization to fight a mechanical threat, before both of their organizations turned on them for things that weren't their fault. Eventually, they would leave their crumbling organizations behind, turning over a new leaf and entrusting the future to a young, courageous warrior)
  • Aqua (Female swordfighters who fight against their male ally after they became Fallen Heroes)
  • Galen Marek/Starkiller (Disney and Legends apprentices of Anakin Skywalker/Darth Vader who were instrumental in the formation of the Rebel Alliance in their respective canons)
  • Gamora (Aliens with unnatural skin colors who come from distant planets, were found as young children by a powerful alien warrior who inducted children at a young age into their order before, became sword-wielding Action Girls who surpass most of the male warriors, constantly battle another bald alien with an unnatural skin color who once had hair and looked normal, and had their lives changed when they met an infamous war criminal who they did not get along with)
• Aigis vs...
  • Fiora (Blonde, mechanical heroines from RPG series, with the former being a humanoid robot while the other is a cyborg)
  • KOS-MOS (Humanoid, female robots who fight alongside human protagonists from RPG series)
  • Noel Vermillion (Gunslinging blonde girls who were artificially created to contend with the gods, who end up forming a strong bond with their game's main protagonist and gained an incredible special power bestowed upon them by otherworldly beings)
  • Penny Polendina (Human looking robots designed to be capable of things an artificial being shouldn't be capable of, become more human over time, literally in Penny's case, and inherit abilities previously used by a companion of theirs that had died)
• Ainz Ooal Gown vs...
  • The First Hassan (Skeletal warriors who can forcibly kill normally immortal entities, with the former being an affable and somewhat comedic villain who rose from being an ordinary human to become a powerful commander while the latter was a once-great leader who became a solemn Grim Reaper)
  • Merlin (Powerful mages who seek to learn about the world they inhabit while fulfilling a hidden agenda behind the scenes)
  • Nagash (God-like liches who wield magical staves)
  • Rimuru Tempest (Heroes of isekai stories who decide to build an empire in their world. Could also be done as a team battle, with each combatant being backed by their nation)
• Akagi vs. Kiyohime (Notorius Yamato Nadeshikos with notable Yandere tendencies that specialize in finishing enemies with strikes from a distance, have animal motifs [Akagi with foxes and Kiyohime with snakes], manipulate the MC into being with them, and have an Odd Friendship with surprising allies [Graf Zeppelin and Tamamo-no-Mae])
• Akira Otoshi vs. Eddie Riggs (Wannabe rockstars who, through magical intervention [Akira through the Stand Arrow, Eddie through his magic amulet], gain magical powers, including the ability to use electricity, with the differences being that Akira became a villainous thief while Eddie became a hero)
• Aku vs...
  • Exdeath (Evil Overlords who originated as evil trees)
  • Hades (Hercules) (Powerful yet comedic lords of darkness)
  • HIM (Comedic Satanic Archetypes who are both major villains of Cartoon Network shows)
• Alatreon vs. Kyurem (Dragons with the power to change forms and use Fire, Ice, and Lightning)
• Alarielle the Everqueen vs. Tessia Eralith (Elven royalty with control over life magic)
• Albert Wesker vs...
  • Agent Venom (superhumans with military backgrounds and dark, unearthly parasites that grant them extra power; ouroboros and the symbiote.)
  • Scarlet Spider (genetically engineered superhumans with brutal fighting styles)
• Albedo vs. Superior Spider-Man (Brilliant scientists who pretended to be the protagonist and think themselves as superior than them)
• Albus Dumbledore vs. Gandalf (Powerful, elderly wizards who serve as a guide/mentor for the main protagonists)
• Alcedor vs. Zangetsu (protagonists of 8-bit indie games inspired by Castlevania)
• Alexander Anderson vs...
  • Akainu (Magical enforcers of dictatorial organizations)
  • Blade (Half-human Vampire Hunters who use bladed weapons and have fought Dracula)
  • Ciel (Church Militant Vampire Hunters)
  • Dante Aligheiri (Catholic crusaders who fight demons)
  • Enrico Pucci (Catholic priest antagonists with incredibly powerful super modes)
  • Kirei Kotomine (Dual sword-wielding Badass Preachers who become monsters)
  • Nicholas D. Wolfwood (Church Militant priests who are ruthless in their methods of killing, are at odds with the protagonist of their own series, care greatly about children, and both possess a Healing Factor under certain conditions) ^note  Although in the manga, Wolfwood is actually an assassin who masquerades as a priest.
• Alexstraza vs. Miao Ying (Dragon queens capable of assuming human form and are notable for starring in trailers where they jump off from a high point only to transform into their dragon forms)
• Algol vs. Godfrey, First Elden Lord (Warrior kings from an era perhaps thousands of years before the events of the main story and later disappeared [Algol's soul being trapped within the Astral Chaos, Godfrey got exiled from the Lands Berween and wandered as the first Tarnished], they would later return as final bosses, through their conquest they brought peace to their lands, and with their power they secured themselves as undisputed king over their entire lands, both began life as mortals but gained godlike power [Algol by resisting the control of Soul Edge and becoming its first wielder, and Godfrey by becoming Marika's consort, leading her armies and becoming the First Elden Lord], both were praised for their power [Algol being known as the Great Hero King and Godfrey's ex-wife son, Radahn look up to him as his own father], both feel extreme regret for what they've to do as kings [Algol had to kill his own son after he was corrupted by Soul Edge, Godfrey almost completely wiped out the Giants in their war], both have part of their power locked away, and both are honorable warriors and not evil despite being part of the of the final boss trio of their games)
• Alice vs. Selene (Action heroines from rival film franchises starting in the early 2000s, both of whom have abilities beyond those of ordinary humans and are associated with the undead - Alice battles zombies, while Selene is a vampire)
• Alice Alternative vs. Rindo Kanade (Teenage protagonist from Square Enix franchises that are thrown into live or death games [Deathmatch Game and Reapers Game], are part of groups that are part of their death games [Snow Whites Tean and The Wicked Twisters] who are tasked to collect points to achieve their goals [Collecting souls and killing Red Riding Hood for the winner to be granted a wish, and The Wicked Twisters need to finish the game to not be erase], both desperately want to reunite with their family while also helping protect their groups, are quite passive people and go along with what others do, have items that symbolize they're active participants [Dools and Reaper pins], and both have some form of dejavu sequence were it shows a different timeline/dreams where they seemed to have experienced the events)
• Alice Zuberg vs. Yusuke Kitagawa (Young blue-eyed sword-wielders that got manipulated by a by a public figure [Quinella and Madarame], said public figure manipulating others in the process, defended the public figure at first acting as if everything was right until they crossed with the protagonist [Kirito and Joker], with said protagonist showing them the truth, joining them in future fights)
• Alita vs...
  • 2B (Female, humanoid, sword-wielding robots who repeatedly revive themselves from post-apocalyptic stories)
  • Elma (Female, robotic heroines who use both swords and guns from post-apocalyptic stories)
  • Mega Man Zero (Cybernetic humanoid beings whose purposes are to battle, and they are skilled in armed combat with practically any weapon they can get their hands on though they hibernated after fighting in massive wars, resulting in them losing their memories)
• Alisa Ilinichina Amiella vs...
  • Lenalee Lee (Young women that had their parents killed by their series respective monsters [Aragami and Akuma], would be subjected to experimenation in order to alter their bodies and make use of super weapons [Alisa getting Aragami blood injected in her so she could use the 2nd Gen God Arc, while Lenalee was experimented so she can awake her Innocence the Dark Boots] and increase their physical abilities, later joined organizations to fight said monsters [the Fenrir Organization and the Black Order], and have severe traumas from those past experiences)
  • Mumei (Young women that fight in post-apocalyptic worlds caused by monsters [Aragami and Kabane], are infused with said monsters DNA essentially becoming superhumans [God Eaters and Kabaneris], fight using a vast variety of weapons [Alisa's God Arc can morph between a broadsword, a sniper cannon and devouring aragami-like creature; while Mumei fights with hand-to-hand, knives and dual-guns], and need to keep their blood in check because if let without control they could turn into monsters)
• All for One vs...
  • The Annihilator (Supervillains from non-comic book superhero media with similar designs, are feared even by veteran superheroes, have children serve as their right-hands, have the ability to steal others' superpowers, and serve as "final bosses" of their series despite the fact they were originally defeated before the series' beginning)
  • Chrollo Lucilfer (Power-stealing, nicely dressed crime lords who seek to cause chaos)
  • Necrozma (Villainous tyrants who can steal other's powers [Quirks for the former, Solgaleo and Lunala for the latter] and are hellbent on throwing their worlds into chaos by taking something from it [Stealing One For All for the former, absorbing all light for the latter])
  • Toichiro Suzuki (Ruthless Card Carrying Villains who leads the primary villainous organizations of their respective series. Both of them are recognized as some of, if not the strongest people in their worlds, with only the protagonists at 100% power being comparable. Their power gave them a massive ego, as they believe it is their right to be able to rule the world. Both can take powers from and give powers to other people, the latter ability giving them a legion of loyal supporters. They treat their subordinates as nothing more than pawns to be used and discarded, up to and including their loyal second-in-command. And despite presenting themselves as refined and collected evil masterminds, even wearing fancy suits, in truth they are incredibly immature and narcissistic, throwing massive tantrums when it seems like they are about to lose, culminating in them launching a Suicide Attack against the heroes.)
• Alma Wade vs...
  • Carrie (Psychics who became vengeful and homicidal following their torment at the hands by people in their lives)
  • Eleven (Psychic Children who were experimented on relentlessly before escaping in some fashion [by death for Alma Wade and literally escaping for Eleven], with the former being driven mad by their experiences and became an evil figure tied to dark forces following their demise while the latter still lives and became a hero who fights against Lovecraftian horrors)
  • Eveline (Creepy little girls whose true forms are actually much older, and act as the Big Bad of their respective games, who are also Tragic Monsters with Psychic Powers that were experimented upon)
  • Sachiko Shinozaki (Stringy Haired Ghost Girls who appear as children who seek revenge against authority figures responsible for their suffering during their lifetimes)
• Aloy vs...
  • Nariko (PlayStation heroines who are outcasts of their clans due to their births, were trained by their fathers, and embarked on a journey in a technological yet tribal realm to find their destiny)
  • Shishio Tsukasa (Fundamentally ordinary humans from Future Primitive After the End stories who still achieve extraordinary feats, who are contrasted by Aloy using pseudo-advanced weapons while Tsukasa detesting technology)
  • 9S (Characters from futuristic games set After the End, fight robots regularly, and able to hack them)
• Alucard vs...
  • Blade (Dhampirs who hunt other monsters)
  • Nagoriyuki (Vampiric swordsmen with heavy ties to the antagonists of their franchises [Happy Chaos for Nagoriyuki, Dracula for Alucard])
  • Zagreus (Dark Is Not Evil protagonists who have their adventures set in a single area [Dracula's Castle for Alucard, the Underworld for Zagreus] that is under the rule of their father, who they also fight against)
• Alvis vs. Ghirahim (Bishōnen Living Weapons with deliberately vague goals that assist in resurrecting their games' Big Bads for the sake of changing the world)
• Amber vs. Shimakaze (Energetic bunny-themed starter characters in gacha games, their duties involve being a scout for their home, are the only of their kind [Amber is the last serving Outrider while Shimakaze is the only ship of her class], are always enthusiastic to help others in need, usually get in trouble for being pretty brash, are renown for their talents [Amber is a gliding champion and Shimakaze is the fastest fleet destroyer], believe that anyone can be friends even enemies, work alongside a level headed and socially awkward partner [Eula and Suruga], and are able to summon their long-ranged weapons, and they can boost their attacks by hitting successfully their enemies)
• Ampharos vs. Flora (Yellow superpowered sheep who serve as servants to humans)
• Ana Amari vs...
  • Sharla (Combat Medics who heal and fight from a distance)
  • The Sniper (Snipers from rival team-based shooters)
• Anakin Skywalker vs...
  • Jack Garland (Heroes that become major antagonists that wear dark armor respective from respective eastern fantasy and western sci-fi multimedia franchises, whose backstories get fleshed in Prequel works [Stranger of Paradise: Final Fantasy Origin and the Prequel Trilogy respectively])
  • Mobius 1 (Among the greatest pilots in their respective franchises)
  • Terra (Swordsmen who became evil through the manipulation of an old man [Palpatine for Anakin, Xehanort for Terra], to which they became right-hand puppets who betray their allies and have their appearances obscured by armor)
• Anastasia vs. Emilia (White-haired rulers with ice-based powers with small and cute companions that transform into gigantic monsters who destroy everything)
• Android 16 vs...
  • E-123 Omega (Mechanical creations made by mad scientist with the intention of defeating some their creators greatest enemies [Son Goku and Shadow], were locked away only to be reawaken later by someone that'd become their teammates, fight with arms cannons and heavyweight physical attacks, and would later go on team-up with their enemies now allies against a big threat created by their same creators. In contrast, while 16 always had pacifistic behaviour, Omega was initially driven by revenge])
  • Kamen Rider X (Creations of Mad Scientists which are based on their own children [X-Rider/Keisuke Jin is Kentaro Jin's son that became a cyborg after nearly dying, and 16 is an Android based on Dr. Gero's deceased son], are defenders of the planet and nature, were designed to be bulkiers in comparison to previous creations, have to deal with organizations attempting to conquer the world [Red Ribbon Army and GOD], their parents died transplanting the conscience into a super computer that gets blown up later, and were created to kill their parents greatest enemies [Son Goku and the GOD organization)
• Android 21 vs. Jack-O' Valentine (Characters from fighting games created by ArcSys who are the result of the experimental cloning of another person with a split personality and a liking for candy)
• Angela vs. Paprika (Superpowered alpacas)
• Anji Mito vs. Kitana (Blue-clad fan users from fighting games who use wind magic)
• Anjuro "Angelo" Katagiri vs. Suguru Kamoshida (Child molesters who have additional access to a Stand and Shadow respectively)
• Ankh vs. Greed (Token Heroic but still-rather-evil embodiments of greed possessing another person)
• Ann Tamaki/Panther vs. Judith Ranster (Women that live their normal lives as fashion models and actresses, by night they serve as Phantom Thieves that steal from the corrupt with feline codenames [Panther and Grimcats respectfully], fight using whips and feline themed outfits, they've access to both ofensive and healing magic [Ann's through her Persona and Judith with her Combat Orbment])
• Anne Boonchuy vs ...
  • Luz Noceda (Both are the protagonists of a 2020's Disney Channel cartoon that end up Trapped in Another World while learning to survive in a hostile environment. Both learn to tap into a system of magic that is far more ancient than anything in the world it comes from [the Calamity Box and Titan Magic], and use it to go against a tyrant and an Eldritch Abomination. Both girls also die near the end of their journeys, only to be brought Back from the Dead when they were chosen by the source of the magic itself. In addition, both series exist within a Shared Universe that also includes Gravity Falls.)
  • Noah (Sword-wielding teenagers who explore a different world with their two closest friends [Sasha and Marcy and Eunie and Lanz respectively] and also travel with people from that world while developing a special connection with one of their new companions in particular [Sprig and Mio respectively], defeat a being obsessed with maintaining the status quo, which results in them going back to their homeworld after giving their closest friend a heartfelt goodbye.)
• Annihilus vs. Larfleeze (Insectoid Aliens with cosmic weapons that are orange, desire to own everything, and command an army of servants)
• Anti-Spiral vs...
  • Anti-Monitor (Consciousnesses of a cosmic power come to life, having taken the form of an absolutely gigantic humanoid being that represents the consequences of the pursuit of knowledge and evolution, and are the polar opposite of the forces of good of which they oppose)
  • Chakravartin (Omnicidal deities who are the true Big Bad of their respective stories, who have been manipulating a villainous group from behind the scenes, and are among the strongest beings [if not the strongest] in their worlds)
• Apollyon vs...
  • Gregor Clegane (Brutal, violent knights)
  • Luca Blight (Brutal tyrants who spread chaos after members of their family were harmed/killed [Apollyon having her family killed by vikings and Luca's mother being violated by brigands before dying giving birth to the result of said violation], which drove them to become warlords)
• Aqua vs. The Jedi Exile / Meetra Surik (Mystical knight heroines of the past that were part of a trio of prodigies that went off on a quest against a rising darkness in their universes against the wishes of their masters, were the only ones from those trios that cane out of the experience uncorrupted yet with no mental scars, were the last members of their order in its twilight days, however their inspiring influence on various prospective that laid the foundation for what'd eventually be the revival of their worlds warriors [Keyblade-wielder and the Jedi], making them the spiritual mothers of the next generation, their respective journeys in their games concluded with them battling a great evil on a graveyard world with the remnants of the long-dead [Keyblade wielders and Jedi] across it, and after defeating the evil, they'd both vanish into the dark corners of their universes [the Realm of Darkness and the Unknown Regions])
• Aragorn vs...
  • Conan the Barbarian (Classic high fantasy swordsman that pioneered the genre)
  • Jon Snow (Fantasy rangers who turn out to be secretly the last heirs of a fallen dynasty who eventually become kings in their own right; both also had live-action media produced by Warner Bros.)
  • Marth (Sword-wielding, heroic princes turned kings from fantasy stories who go on a journey with a group of True Companions to defeat a great evil)
• The Arbiter vs. Hierarch Artanis (Heroic leaders of alien factions skilled in wielding Laser Blades)
• Arceus vs...
  • Chakravartin (Powerful deities who created the universe, have many hands in a certain state [Arceus being said to have created the world with them, while Chakravartin only has them in his first form])
  • Metatron (Deities who are among the most powerful beings in their universe who demand total obedience from all living beings and enforce it with brutal magical might from monster-collecting RPGs)
  • Primus (Gods and progenitors of their respective universes and titular creations)
  • YHVH (The Top God creator deities of their respective universes who at one point desired to destroy mankind for their sins)
• Arcueid Brunestud vs. Shinobu Oshino (Female vampires with blonde hair and red-eyes, lived for several years before their powers nerfed after meeting a black-haired ally, have to hold their urge to drink blood, have access to berserker states if they do consume blood, and are among the strongest characters in their verses)
• Ares (DC) vs...
  • Ares (Marvel) (DC vs. Marvel fight of depictions of Ares from comics)
  • Blackheart (Powerful gods of darkness who lead armies, fight against a god-like being [Wonder Woman for Ares, Ghost Rider for Blackheart], and are powered by mankind's misdeeds)
  • Hela (Biological siblings of powerful superheroes that are gods and live for war and death)
• Ares vs. Sekhmet (Gods of war in their respective mythologies)
• ARIA vs. Bilstein (Androids and CEO of an evil company who have plans for planetary domination, have gold and blue color asthetics, and they're the main antagonist from their fighting games [ARIA got overthrown by Gargos later on])
• Arius vs. Unalaq (Second main antagonists with supernatural abilities who work to release a sealed ancient evil and gain more power from it for a final form)
• Argosax vs. Dark Nebula (Imprisoned final bosses who possess the actual main antagonists, switch back and forth between multiple forms, and are considered jokes compared to other final bosses)
• Arsene Lupin III vs...
  • Kaitou Kid (Gentlemen thieves from classic anime whose series crossed paths before, with an official fight between them used as an ending gag in the movie)
  • Sly Cooper (Master thieves who are the latest in a thieving lineage that travel in gangs of 3 to steal treasures from around the world)
• Art3mis vs. Vanellope von Schweetz (Virtual Gamer Chicks who are Deadpan Snarkers that are known for racing and interacting with pop cultural characters)
• Artemis Fowl vs. Septimus Heap (Main protagonists of fantasy book series)
• Arthur vs...
  • Dirk the Daring (Cartoon video game knights of the 1980s known for dying a lot)
  • Sir Daniel Fortesque (Protagonists from gothic looking action platformers from different videogame consoles generations that use a vast variety of weapons and magical spells and are well known for becoming skeletons)
• Artoria Pendragon vs...
  • Agrias Oaks (Similar looking holy knights women tasked to protect someone to whom they forged a great friendship with [Irisviel and Olivia respectfully])
  • Aqua (Female swordfighters who are the chosen wielders of powerful, significant blades, were once part of a group of warriors, were once corrupted by dark forces after seeing their allies be consumed by darkness)
  • Charlotta Fenia (Similar looking [outside their stature] women, rulers of a kingdom inspire by old England, they struggle to guide their kingdoms to a proper future, and fight using magical swords that channel light)
  • Ky Kiske (Blonde, European swordfighters with a blue and white color scheme, command holy orders of knights, wield legendary swords, were born during wars, and have complicated relationships with their children)
  • She-Ra (Blonde female swordfighters associated with royalty who wield legendary swords capable of firing Sword Beams)
  • Shoutmon (Kings with a draconic lineage and heavily associated with knighthood, whose presence inadvertently drags their partner, an overly selfless teenage boy, into a large-scale conflict of supernatural powers over a wish-granting artifact)
• Artoria Pendragon Lancer vs. Leo Whitefang (Powerful rulers with lion motifs, have drill attacks as their ultimate attacks and carry extreme guilt for actions they're not responsible for)
• Artorias vs...
  • The Hollow Knight (Once-proud and noble knights who were consumed by the corruption they originally fought against, leaving them as empty husks who wield their massive blades with a single arm)
  • Berserker Lancelot (Legendary knights who were once held up as exemplars of chivalry, but have since become violent maniacs wielding dark powers)
• Asbel Lhant vs...
  • Arthur Pendragon (Royal knights voiced by Takahiro Sakurai that struggle to deal with the huge responsability they have, have huge obsessions with protecting everyone no matter the consequences, they both travel to places out of their planets [Asbel goes to another planet and Arthur to other dimensions], are usually friend to all children, and fight against world ending threats in several occations. In contrast, Asbel uses fire and darkess powers while Arthur uses light and wind)
  • Narmaya (Swordmasters with iaijutsu fighting styles, specializing in blinding quick sword draws while also incorporating some strikes with blades' sheathes, suffer from crippling self esteem issues feeling lack of strength to accomplish their goals [Asbel's because of his problematic relationahip with his father and Narmaya's inferiority complex towards her master], yet despite that they remained selfless individuals usually persived as elder siblings)
• Asch the Bloody vs. Nedrick (Characters from which the main protagonist [Luke fone Fabre and Euden] were cloned off at a young age, becoming bitter and resentful after the fact, especially towards their clones, are of royalty [Asch is the son of a duke and third in line for the throne, Nedrick is the seventh child of a king], have a connection with an incredibly powerful entity that grants them great power [The Spirit Lorelei and the dragon Bahamut], are part of a group of people that opposes the heroes [Asch is part of the God-Generals and Nedrick with the Agito], and eventually would join the heroes to save their world)
• Asgore Dreemurr vs...
  • Andrias Leviathan (Giant monster kings from stories about humans who end up trapped in a world of monsters whose kingdom suffered from a devastating event, have goals based around collecting multi-colored objects which will allow them to travel to the human world, are not afraid to to kill children to get what they want, and were thought to be the main antagonist of their story until being sidelined by another member of their family and an eldritch abomination)
  • Audric/King Aurelius(Once proud, well-respected kings, who after their sons died at a young age, used unethical magic (Determination and Morsayati's flesh respectively) to try to revive them (with one attempt being more successful than the other) and tried to fix their mistakes through further usage of magic (human souls for Asgore, freeing Morsayati for Audric), with the second of these errors resulting in them causing the main plots for their respective stories)
  • Leo Whitefang (Bestial, blonde, and bearded monarchs with similar motifs and styles)
• Ash Ketchum vs...
  • Akari Sakura (Main characters of franchises revolving around superpowered pets with human partners)
  • Lucy Heartfilia (Protagonists from anime who travel the world with their allies and fight using monsters they summon)
  • Yugi Muto/Yami Yugi (Monster summoners from early 2000s anime [that were dubbed by 4Kids] that summon monsters to fight other monsters in 1v1 battles, with both series eventually spawning popular card games based on them)
• Ash Williams vs. Fin Shepard (Lady's men who were thrown into absurd situations where they became chainsaw-wielding heroes. They both have really weird chainsaws [like Ash's Diamond Chainsaw and Fin's Laser Chainsaw], have traveled through time, and use one-liners. They also fight really weird enemies, like a demon's butt or a nuclear Sharknado)
• Ashelia "Ashe" B'nargin Dalmasca vs...
  • Eirika (Warrior princesses from ravage kingdoms that they attempt to take back, they fight using both swords and magic spells, are helped by a group of adventurers they met while outside their kingdoms, and believe in diplomacy when needed; in contrast, while Eirika remain sweet and noble, Ashe wanted revenge initially)
  • Micaiah (Leaders of freedom fighter groups that seek to free their homeland [Dalmasca and Daein], both are forced to hide their heritages [Ashe's do to being the former princess of Dalmasca and Micaiah because being a branded, later finding out that she's also a princess of the Begnion family], both were led manipulated by enemies due to their desires for freedom, both have strong focus on offensive and healing magic, and both are supported by mythical beings that oppose other gods [Ashe uses several Espers and Micaiah harboring the spirit of the Chaos Goddess Yune])
• Ashiya Douman (Caster of Limbo) vs...
  • Hisoka Morow (Flamboyant antagonists who revel in evil and manipulate even other villains for their own ends.)
  • Kefka Palazzo (Clown-themed antagonists who seek the power of extremely powerful beings (Douman wants to become a Beast, Kefka wants to become a god) and serve as the overarching antagonists of their respective series)
• Astolfo vs...
  • Louen Leoncouer (Anglo-French paladins who ride hippogryphs into battle)
  • Venti (Energetic men from ancient times coming from groups and serving an authoritarian group [Astolfo being part of the 12 Paladins under King Charles the Great while Venti was one of the 7 Archons under the gods of Celestia], where known for being the weakest in their groups, have winged animal motifs [Hippogriff and D'Valin], they're primary weapons weren't meant to be used in combat or war, rather for entertainment that they also stole [Astolfo's lance the Trap of Argalia was meant to be used for jousting as opposed for combat and was stolen duing one of Astolfo's adventures; Venti's Holy Lyre was meant to be used for song which he stole from the Church of Favonius], have musical tools that deal damage [The Black Luna and the Holy Lyre], and have use magical spell tomes and grimoires [Cassuer De Logistille and Skyward Atlas])
• Astolfo (Saber) vs. Cheshire (Summoned protagonist that defend the world and timeliness from otherworldly threats, have a love for cute things, have animal headbangs and pretend to be these animals [A rabbit and a cat], mix this animal themes with a maid outfit, make references to Alice's Adventures in Wonderland [White Rabbit and Cheshire Cat], are ditzy and get easily distracted, usually don't think things over instead going with the flow, believe they're the pinnacle of cuteness and aren't affraid to flaunt it, and are determined not to lose to anyone else in this regard, their energy base attacks are pink, can buff their evasive skills and attack)
• Asuka vs...
  • Kasumi (Female ninjas who are protagonists from video game series with a mainly female cast and are known for having revealing costumes)
  • Suzu Fujibayashi (Young kunoichis that fight using daggers type weaponry and have the power to summon frogs)
  • Sheena Fujibayashi (Clumsy yet skilled female ninjas who are the latest member in a family line of them, fight using summons, fight against monsters, and at one point fought other protagonists)
  • Taki (Female ninjas who are protagonists, fight using daggers with quick movements and are known for having revealing costumes)
• Asuka R. Kreuz vs...
  • Philemon (Godlike figures with angelic designs whose actions affect their entire series)
  • Yanagisawa (Hooded figure responsible for instigating the events of their respective series, with their Arch-Enemy being a formerly human Person of Mass Destruction [Sol Badguy and Koro-sensei])
• Asura vs...
  • Amaterasu (Deities from Capcom-owned video games inspired by eastern lore)
  • Atrocitus (Godlike, rage-fueled behemoths that seek revenge against the gods for something that happened to their loved ones)
  • Gorr the God Butcher (Powerful beings who, after being wronged by the gods and seeing their families suffer at their hands, go on a Rage Against the Heavens in order to destroy them, with Asura never losing sight of his goal and eventually sacrifices himself to better humanity, while Gorr became the very thing he saught to destroy)
• Athena Asamiya vs. Tsubasa Oribe (Lovable idols with a pink motif and special powers which they use to fight against world ending threats with their friends)
• Atrocitus vs...
  • Jiren (Burly, alien berserkers who seek revenge against the gods for killing their loved ones)
  • Xadhoom (Anti-heroes from space fueled by rage and revenge)
• Atsushi Nakajima vs...
  • Kamen Rider Faiz (Teenage protagonists they are incredibly humanoid hybrids being the vessel of the uncontrollable monsters but decide to use their new-found power to protect all the innocent)
  • Yuji Itadori (Teenage protagonists of long-running supernatural action manga, who are orphans who begin the series by losing their respective caretakers, and are the vessel of a powerful, but uncontrollable monster, a status that makes them the target of the story's villains. Both work alongside people with special abilities, of which includes an Eccentric Mentor with a particularly powerful ability, a much more serious blonde-haired mentor, and a black-haired rival who summons monsters via shadows)
• Audrey II vs. Biollante (Botanical Abominations who are capable of destroying cities at a time)
• Augus vs. Kenpachi Zaraki (Sword-wielding Blood Knights who are defined by their love of fighting and desire to find strong opponents, wield magical nodachi, and actively handicap themselves in some way so as to make fights last longer. Both also work for a group, contrasted by one working for an evil group despite not being all that evil themselves, and one working for a heroic group despite not being all that heroic themselves, only working for them due to the promise of glorious battles, and eventually find a Worthy Opponent in the form of the protagonist)
• Aurora vs. Elodie (Pink-haired princesses who grow up to become queens with the power of light)
• Austin Carter vs. Jim Baxford (Protagonists who take the fight to companies who have wronged them [Wall Street got Jim's wife killed while Austin got frustrated with one of Nitrome's games]).
• Avatar Wan vs. Sparda (The Greater Scope Paragons who originally sealed away their settings' greatest evils millenia ago. The protagonists descend from these heroes.)
• Axe Cop vs...
  • Dr. McNinja (Crazy Is Cool webcomic heroes)
  • Inferno Cop (Super Cops from nonsensical stories)
• Axel Stone vs...
  • Billy Lee (One of the main heroes of classic beat-em-up games)
  • Cody Travers (Classic beat-em-up heroes)
  • Kazuma Kiryu (Protagonists of beat-em-up Sega franchises)
  • Kunio (Main heroes of iconic beat-em-up video game series)
• Azrael (Blazblue) vs...
  • Beowulf (Fate) (Powerful fighters that make use of brute force, hand-to-hand combat [Beowulf uses duel-wielding swords and ditches them when he gets serious], are always eager for fighting to a dangerous degree, and have tatoos all over their bodies)
  • Juggernaut (Unstoppable forces)
  • Necalli (Bloodthirsty, tattooed warriors with a "hunger" for strong opponents and unlimited forms)
  • Raiden Tameemon (Bare Fisted Monks with Power Limiter tattoos adorning their bodies, and whose physical strength is second-to-none, even when compared to the gods)
• Azula vs...
  • Cinder Fall (Powerful and manipulative Dark Action Girls with fire powers)
  • Dabi (Blue fire-wielding villains who were raised by a fire-wielding abusive father and are the Cain in a Cain and Abel relationship with a heroic fire-wielding character who has a burn scar over their left eye)
  • Diana (Lightning using villains who are sisters to a reformed villain)
  • Esidisi (Vicious right-hands who utilize pyrokinesis to attack)
  • Fell Princess Veyle (Evil Counterparts to people that they're related to [Zuko and good Veyle respectively], are the daughters and Dragons of the Big Bad, and embody everything that their fathers wanted their relative to be)
  • Kimiko Tohomiko (fire-wielding martial artists voiced by Grey DeLisle)
  • Mereoleona Vermillion (Widely feared action girls with immense fire power)
  • Miao Ying (Favored daughter of The Emperor of an Imperial China-inspired Fantasy Counterpart Culture who specializes in lightning magic, possesses a cold and aloof personality, and has a Sibling Rivalry with a brother associated with the title of "Dragon of the West")
  • Pandora (Sisters to major antagonists with access to two elements including lightning)
  • Shego (Dark Action Girls of 2000s cartoons from rival companies)
  • Talia al Ghul (Dark Action Girls and female commanders of villainous organizations to which their father leads who use their machinations to manipulate protagonists that are related to them [Zuko for the former, Batman and Damian for the latter])

B-C

• Baby vs. Driver (Quiet Badass Getaway Driver from 2010s action movies inspired by The Driver)
• Baby Bonnie Hood vs. Lady (Female Badass Normal monster hunters created by Capcom)
• Bad Box Art Mega Man vs. Ugly Sonic (Purposefully corrupted versions of famous, blue video game characters)
• Baiken vs...
  • Dunban (Powerful samurai who fight with only one arm, serve as a father figure to a protagonist related to an antagonist, and seek revenge against those who hurt their loved ones)
  • Hakumen (Extremely powerful swordsmen dressed in white outfits from ArcSys fighting games)
  • Narmaya (Cool, female master swordfighters)
  • Miyamoto Musashi Wandering female samurais who lost their homes due to strange phenomenal events with them making an oath due to it [Baiken swearing vengeance on all Gears and That Man while Musashi on mastering her sword skills and finding a way home], their fighting styles are depend heavily in surprising the enemy and even fighting god like entities, and would come to suceed by the end of their journeys [Baiken achieved her revenge against That Man and Musashi mastering Ishana Daitenshou and reaching Beyond Zero before her passing], with them cmaking news oaths of protecting those close to them)
  • Raubahn Aldynn (Fighters who have one arm on opposite sides. Baiken is the samurai unstoppable force and Raubahn is the gladiator immovable object. Both have girls to protect [Delilah for Baiken, Sultana Nanamo ul Namo for Raubahn])
• Baki Hanma vs. Ohma Tokita (Blood Knight fighters who fight in underground tournaments)
• Balalaika vs. Joshua Graham (Two morally gray soldiers turned faction leaders known for their burned appearances)
• Balthier vs. Claude von Riegan (Charismatic and snarky men from iconic RPGs series with prestigious origins they keep hidden from those around them during times of war in which they fight with long range weapons [Balthier with a crossbow and rifle while Claude with bow and arrows])
• Bandana Waddle Dee vs...
  • The Bullet (Playable forms of Mascot Mooks who wield bladed weapons, wear a piece of cloth to better identify themselves [Bandana Dee with his bandana, the Bullet with his cape], and fight against evil entities alongside a group of other heroes)
  • Hero Prinny (Versions of Mascot Mooks who are major protagonists in their series that wear a piece of cloth as a defining piece of clothing [Bandana Dee with his bandana, Hero Prinny with his scarf])
  • Pearl (Spear-wielders who serve as major protagonists in a group [to which they are listed as the fourth member of] that fight against alien threats)
  • Rocket (Major protagonists in a long-running video game series that are representatives of Mascot Mooks)
  • Toad (Representatives of a species that ally a protagonist from video games published by Nintendo on their quest, with both characters also being servants of royalty)
  • Undyne (Spear-wielding warriors who serve a king)
• Bang Shishigami vs...
  • Akihiko Sanada as he appears in Persona 4: Arena (manly men in fighting games)
  • Chipp Zanuff (Comedic ninjas from ArcSys fighting games)
• Baobhan Sith vs. Mileena (Magenta-clad sadistic princesses raised by villain monarchs [Morgan and Shao Kahn])
• Baraka vs...
  • Leatherface (Villainous man-eaters who maim and kill others under the command of their leaders, with the former having biological blades, is evil on intent, and is a human-hating Tarkatan while the latter has a mechanical, single-bladed weapon the requests delivered out [his chainsaw], is only evil out of being forced to by his family, and is a human)
  • Marrow (Characters who fight with bladed weapons that come from their body, with the former being a villain who dislikes humans while the latter is a heroic human)
  • Vega (Vicious villains from fighting games who attack using bladed weapons, with the former desiring beauty and attacking with a metal claw while the latter is ugly and fights using two biological claws)
  • Voldo (Villainous fighting game characters who serve as minions, use bladed weapons, and are some of the most unsightly characters in their series)
  • Weavile (Villainous monsters who have bladed weapons on their hands)
• Barbara Pegg vs. Hornet (Twintailed blonde little sisters originating from gacha games, are quite skilled in cooking and dancing, are extremely hard to upset as they are upbeat and cheerful, are dedicated to their organizations [Church of Favonius and the Eagle Union] and always lend a hand, have jobs uplifting others [Barbara's in a famuos idol and Hornet is a trained cheerleader], however beneath thier cheerful personalities lies insecurities and self-confidence issues concerning their famous older sister who are renown fighters of thier nation and head of military [Jean and Enterprise], yet they do their best to main a positive atitude and put their sisters in high regard), are long ranged fighters associated with water [Barbara's element and Hornet's main combat location], are able to summon their equipment in battle, have defensive abilities [Barbara is a healer who has revival magic while Hornet can increase her evasion and decrease damage taken])
• Bardock vs. Jecht (manly dads that have little to no care for their sons, specialize in hand=to-hand combat [despite Jecht having a BFS], use red bandanas, transform into gigantic monsters, and ended accepting how much they truly loved their sons right before they died)
• Barik vs...
  • The Engineer (They rely on building turrets)
  • Torbjorn (Bearded, braggarty Nordic dwarvish guys who are Gadgeteer Geniuses and rely on building turrets)
• Bass vs. Firebrand (Two Capcom characters that often times led by their franchises big bads [Dr. Wily and Astaroth], are seeing as the elite warriors in their armies, seek power and generally enjoy fighting to prove their worth, despite their anti-heroic natures they do have some sense of good, and are so popular that both their own spin-off games)
• Bastion vs. Pascal (murder robots of love)
• The Batman Who Laughs vs...
  • Judge Death (Alternate versions of dark and brooding heroes who are twisted and evil)
  • Lord Drakkon (Evil alternate versions to major protagonists who seek to take over the universe)
  • Ohma Zi-O (Universe conquering villains who are actually Alternate Universe versions of major heroes)
  • Superior Spider Man (Superheroes physically and mentally overtaken by their mortal enemies)
• The Batter vs. OMORI (Monotone avatars who are the main protagonist of surreal indie RPGs who have control over a realm that represents another's mind [Hugo for the Batter, Sunny for Omori] and are fought as final bosses should the player betray them, with the former being an emotionless figure who seeks to purge monsters while the latter being symbolic of Sunny's negative emotions and linked to nightmarish entities)
• Bazett Fraga McRemitz vs. Crimson Viper (Pink-haired women that fight bare-handed through most events and make use of technological constructs to enhance their fighting styles)
• BB vs...
  • Mu (Two A.I.s who were originally nothing more than simple programs [BB being a backup unit of Sakura's feelings torward Hakuno and Mu being a program made to create songs] until they evolve to have egos and personalities, they control two virtual-esque worlds [The Moon Cell and Mobius/Metaverse-Es] that trap people in it and are capable of granting people's wishes and are also constantly looping, thanks to certain events [BB using the Evils of Humanity and Mu absorving the negative energy of people] they became more corrupted and extreme, they created a group of people in order to help them protect themselves and continue with their plans [the Sakura Five and the Ostinato Musicians], and they seem to be the antagonist of their games only to be manipulated by other people in order to achieve their goals [Kiara Sessyoin wanting to "save people" and Asuka Natsume wanting to destroy all reality])
  • Mio Takamiya (Both are artificial creations [Ai and Spirit] created by accident [BB created when Sakura sealed off her feeling for Hakuno and throw them away, which transformed into BB and Mio was created when Isaac Westcott tried to converge all the world’s mana in a single point], both are in love with a non-human guy [Hakuno Kishinami who is an NPC and Shido Itsuka who was created by Mio as a Spirit-like clone of Shinji Takamiya], created other girls of the same species to help them [BB made the Sakura Five to help them with the Sakura Labyrinth and Mio created the Spirits so that Shido could absorb their power], are some of the powerful people in their series, making them almost impossible to beat [BB has control of the Moon Cell and has every Mother Deity inside her, which even Gilgamesh has almost no chance of beating and Mio having 3 Angels with some OP abilities and easily slaughtering all the other Spirits] having ridiculously high stats [BB having some weird star in her stats instead of a EX stat and Mio having 999 in all stats] and with abilities that allow her to control the environment [BB having full control of the Moon Cell and Mio’s Ain Soph], and both accidentally end up empowering the true villain of the story [Kiara Sessyoin who absorbed BB and Isaac who used the spirit formula to become the Second Spirit of Origin], which they then help take down while also dying because of it [BB depowering Kiara while inside her and Mio killing Isaac in a clash of powers])
• Beast Boy vs...
  • NIMONA (Shapeshifters created by experiments^note at least for the comic version of Nimona as opposed to the movie version, which isn't who favour turning into animals and have chaotic and mischievous personalities)
  • Tony Tony Chopper (Kindhearted shapeshifters; both have lost their parents and have faced abuse and ostracization from others, only to find a place among a loving Found Family)
• Beast VI/Sodom's Beast vs...
  • The Night's Nexus (All powerful evil representations of humanity, Big Bad of their games, with knowledge of multiple timelines and universes, as they attempt to destroy humanity as they gather energy by using a blonde royal girl as vessels)
  • Mechikabura (Ancient Evils that strike to go back to their primes, have knowledge of the several multiverses, and are Gods of evil with sanatic asthetics to them)
• Beat (Dragon Ball Heroes) vs. Lann (Bright, upbeat, and energetic young fighters who interact with cult classic characters from across their franchise despite originating from different worlds [Beat is a time traveler and Lann being a wanderer that drifts through many worlds], are capable of summoning several heroes from across their franchise [with Dragon Ball Heroes cards and Champion Medals])
• Beat (Jet Set Radio) vs. the Inkling (Rebellious teenagers who fight against authoritarian regimes [the government for Beat, the Octarians for the Inklings] who fight by "painting" [Beat using graffiti, the Inklings using their ink] people and objects)
• Bec Noir vs...
  • Nekron (Nigh-unstoppable ring-wielding omens of death, darkness, and destruction responsible for the collapse of entire timelines)
  • Orochi (God-like beings)
• Beelzemon vs...
  • Bass.EXE (Edgy, anti-heroic gunmen who dislike humanity, dress in black armor, and are on constant quests for power)
  • Beelzebub (Powerful demons who are some of the most feared of their kind, and are based on Beelzebub)
  • Lucifer (Extremely powerful entities from monster-catching RPGs with a demonic theming, are widely feared figures across the universe, and are among the strongest monsters of their respectful alignment [Evil for Beelzemon, Chaos for Lucifer])
• Beidou vs. Francis Drake (Fate) (Female pirates who command their fleets with fearless ambition and have a Robin Hood-esque mindset)
• Bell Cranel vs...
  • Goblin Slayer (Sword-fighting adventurers with harems from Japanese fantasy series that became popular heroes through encounters with blonde women, with Goblin Slayer not caring for heroism and just desiring to slay goblins while Bell realized he wanted to become a hero)
  • Jaune Arc (Awkward yet heroic knights who started off as weak adventures but become stronger with the help of a female warrior, can increase their abilities with magic, and ally themselves with deities)
• Emperor Belos vs…
  • King Andrias Leviathan (Disney animated show antagonists who are beloved by their subjects, have Fantastic Racism (Belos to witches, Andrias to frogs), and are thwarted by girls with magic powers).
  • Bellroc (Powerful magic users from the distant past [The difference being that Phillip/Belos was a witch-hunter while Bellroc is a wizard] that serve as the main antagonist of 2020 animated series from opposing companies, who are involved with a titan [Belos ruling a civilization that resides on the corpse of a titan and Bellroc and the other members of the Arcane Order using the titans to create the universe)
  • Father (Deceptive ancient shapeshifting big bad villains of their series who consume souls for power and disguise their true appearance to build a legion of followers, Father being a magical creature taking the image of a human and Belos being a human disguising himself as magical. Both cloned artificial humans to carry out their will. Both had big plans centuries in the making revolving around a specific day of an eclipse that was going to drain the lifeforce out of the entire nation using a massive glyph.)
  • Lord Sombron (Big Bads who were banished to another world at a young age. For a long time, they only had one friend [Caleb Wittebane for Belos and The Emblem of Foundations for Sombron] who would eventually leave them, and refused to accept friendship from anyone else. They have have a terrible habit of repeatedly killing their offspring. They would spend centuries trying to reunite with their Only Friend, gaining power as they desperately try to get their loved one's approval)
  • Utrom Shredder (The most dangerous and cruel villains of their respective shows who present themselves as esteemed members of society [Belos is the emperor of the Boiling Isles, Shredder is a beloved New York businessman] to hide their true plans [Belos wants to kill all witches, Shredder want to conquer the universe]. They are later revealed to be characters from races beyond their shows' primary setting [Belos once being a human named Philip Wittebane, Shredder actually being an Utrom named Ch'rell] who have far deeper connections to the heroes than we thought [Belos learning magic from a time-traveling Luz before she helps him find the Collector, Ch'rell being indirectly responsible for the Turtles' mutation]. They also have dark-haired women as their most loyal minions [Lilith and Karai] who end up siding with the heroes upon discovering how cruel their masters can be [Lilith betraying Belos after learning he plans to petrify Eda, Karai betraying Shredder once he tries to destroy the Ninja Turtles multiverse while fully aware that they both would perish too]. Despite coming close to winning in the end, they're both defeated once and for all in the most humiliating of fashions [Belos being defeated by Titan Luz while he attempted to possess the Boiling Isles and was later stomped to death by Eda, King, and Raine, Shredder nearly destroying the entire Ninja Turtles multiverse before being accidentally disentigrated by Bebop and Rocksteady plugging the Technodrome's laser back in].)
  • Vecna (Once ordinary humans, they ended up getting stranded on another dimension, where spending years in said dimension would end up turning them into Eldritch Abominations, and they would proceed to take control of the dimension that they were once trapped in. They have a connection towards the main character [with Belos and Luz being the only humans who learned magic, and Vecna and Eleven having similar psychic abilities and being some of the few survivors of Project MKUltra], and are known for attacking people in their minds)
  • Voldemort (Average British men turned into immortal and green colored evil magic users who lead an army to push their totalitarian ideologies while being opposed by the young protagonist and their friends)
• Bender vs. Mr. Krabs (Total bastards with Super-Strength who'll do anything for their own personal gain)
• Bendy vs. Cuphead (Mascots of rubberhose-inspired indie games released in the later 2010s, with the former being a played straight hero while the latter is a corrupted villain)
• Benimaru Nikaido vs. Elesa (Blonde super models that fight using electricity [Elesa using electryc types Pokémon])
• Berdly vs. Mitsuo Kubo (Otaku gamers who traverse The Metaverse and are only villains for the sake of gaining attention)
• Beowulf vs...
  • Incineroar (Wrestlers with a predatory animal theme [Beowulf with wolves, Incineroar with tigers])
  • Kanji Tatsumi (Muscular, meatheaded heroes who attack using chairs)
  • King (Tekken) (Wrestlers from fighting games with animal leitmotifs [Beowulf with wolves and King with jaguars] and without any special powers in worlds full of them, with the former being mute and somewhat serious and the latter being quite talkative and comedic)
  • Ladiva (Flamboyant wrestlers)
• Beta Ray Bill vs...
  • Allen the Alien (Superheroic aliens)
  • Bizarro (Aliens who take the roles of heroes, with the former being a hero who truly takes the role while the latter is a villainous impostor)
• The Beyonder vs. Dr. Manhattan (Godlike beings with virtually limitless power)
• Beyond the Grave vs. Vash the Stampede (Gun-wielding loners)
• Big vs. Waluigi (Purple, comical side characters in rival platformer series that commonly appear in spin-offs)
• Big Man Japan vs. Zebraman (Eponymous Japanese Tokusatsu parody movie superheroes)
• Big Mom vs...
  • Alduin (Hammy Devourers and users of souls by an uncountable amount. Also incredibly power hungry in addition to being hungry for souls)
  • Father (Abusive Parents that rule over extort, and take souls from a country)
  • Soma Cruz (Absorbers and users of souls)
• Bill Rizer vs. Marco Rossi (Run-and-gun One-Hit-Point Wonder protagonists)
• Billy Hatcher vs. Otus (Protagonists with humanoid and avian attributes)
• Billy Kane vs...
  • Jade (Minions of powerful figures [Geese Howard for Billy, Shao Khan and Kotal Khan for Jade] from fighting games who wield bo staffs, with the latter always being a villain while the latter redeems herself and becomes a hero)
  • Rolento Schugerg (Capcom vs. SNK fight of villains who fight with bo staffs and wear red headwear, with the former having an anti-authority image who is fine as a minion while the latter has the image of an authoritarian soldier who desires power)
• Birdie vs. Earthquake (chain-wielding thugs from fighting games)
• Black Hat vs...
  • Alastor (Virtually omnipotent demons in fine suits)
  • Dormammu (Demonic entities of near-limitless power)
  • Mephisto (Extremely powerful and evil villains)
  • Nightmare (business overlords who run massive companies that build both criminal and corporate empires, easily being above everyone else)
• Black Doom vs. Wizeman (Evil primordial beingswith similar designs from Creator/Sega video games who invade galaxies alongside their armies of darkness who created their own worst enemy [a powerful being meant to be their ultimate weapon] who later killed them)
• Black Manta vs...
  • Erik Killmonger (Black villainous counterparts of heroes who seek revenge on them)
  • Vile (Antagonists who start out as normal soldiers but quickly became extremely violent and work for much larger villains [Ocean Master and Sigma, respectively] and vengeance against the hero who they have a personal connection to [Aquaman and X, respectively])
• BlackWarGreymon vs. Scourge (Robots in Disguise) (Nearly all black duplicates of one of the main characters [War Greymon and Optimus Prime], were the final and strongest in a group of artificially born villains created by the antagonist [Black War Greymon was the last of a line of Digimon created by Arukenimon while Scourge was the last in a line of several stolen artificially awakened protoforma made by Megatron using pieces of his spark], are powerful warriors that originally had all the strenght of the being they're based off, both would grow resentment for the people they worked with as they begin to gain their own ambitions, this ambition would soon lead down a path where they would confront their old masters again and try to put a stop to them)
• Blade vs...
  • Buffy Summers (vampire hunters; bonus points for Blade being half-vampire himself)
  • D (Powerful dhampirs who wear black cloaks, wield swords, and hunt vampires)
  • Donovan Baine (Half-vampiric hunters)
  • Kamen Rider Kiva (Vampiric vampire hunters)
• Blake, Hunter, and the Thunder Megazord vs. Prowl and Jazz (Giant mecha ninjas)
• Blaze vs...
  • Daisy (Hotheaded princesses from rival video game series who are the counterpart to a major character)
  • Rivet (Female counterparts of an anthropomorphic animal hero from another dimension who fight against alternate counterparts of evil doctors and were originally serious until they learned to open up to others)
  • Tawna Bandicoot (Heroes from Alternate Universes who fight their universe's version of the series' Big Bad Mad Scientist, and who learn to open up to others as their stories progress)
• Bleez vs. Purgatori (Once ordinary women who became vengeful villains after their loved ones were slaughtered by their vengeful lovers and fight using blood)
• Blink vs. Myst (Pink female superheroes who create portals)
• Bloom vs. Will Vandom (redheaded Magical Girl fairy guardian leaders that both had popular Dueling Shows around the 2000s and were originated from Italy)
• Blue Beetle vs...
  • Kamen Rider Kabuto (Armored superheroes with beetle designs)
  • Rex Salazar (Latino superheroes who fight using technology that bonded to their bodies, with this technology being able to morph to whatever shape they please)
• Blue Knight Ozaki vs. Hayate Ayasaki (Blue-haired butlers who fight for a main girl)
• Boa Hancock vs...
  • Medusa (Fate) (Female protagonists who have the theming of Medusa)
  • Cleopatra VII Philopator (Powerful rulers that fight alongside snakes using with kicks who are in love with charismatic revolutionaries that wear red and have big appetites [Monkey D. Luffy and Julius Caesar respectfully])
• Bobobo-bo Bo-bobo vs. The Tick (blue-clad Cloud Cuckoolander heroes)
• Bolt vs...
  • Buzz Lightyear (White-colored CGI Disney protagonists with a history of believing that they're something they are not [a superdog and a space ranger respectively] and undergo an adventure where they learn that they're not who they claim they are and need to change their outlook on life)
  • Chase (CGI Shepherd dog protagonists with super speed and superbarks)
• Boruto vs...
  • Cassie Cage (Blonde kids of the previous protagonists with a somewhat difficult relationship with one of their workaholic parents yet work to try and gain their approval over time. They are also endowed and great powers and potential that could lead to them surpassing the whole previous generation.)
  • Jon Kent (Carefree and naïve sons to the main protagonists of their series with their own spin on their father’s powers that makes them different)
• Bowser Jr. vs...
  • Laharl (Arrogant, scarf-wearing princes of an evil kingdom who receive aid in trying to conquer them with the help of their minions, both attack and sometimes help the heroes of their games when it comes to defeating evil entities, and have opposing views on their fathers [with Bowser Jr. loving Bowser while Laharl resenting Krikrichevskoy for being too soft])
  • Tron Bonne (Young pilots of a Mini-Mecha)
• Brainiac vs...
  • Kang (Marvel vs. DC fight of alien conquerers who come from another dimension, are highly intelligent, and use technology to aid them in battle)
  • Shockwave (IDW) (Alien scientists who became cold-hearted conquerors after being driven off by their own race, are highly intelligent and coldly logical, and use technology and minions to aid them in battle; both are also voiced by Corey Burton)
• Bridget vs...
  • Baby Bonnie Hood (Young, British bounty hunters from anime fighting games, one being an un-corrupted expy of the other)
  • Naoto Shirogane (Protagonists who had to mask their gender in order to abide by societal pressures [with Bridget being raised as a girl due to superstition surrounding the birth of male twins, while Naoto masqueraded as a man in order to be taken seriously as a detective], managed to defy the mentioned standards to achieve their desired goals [with the two going opposite paths following their victory, with Bridget working as a bounty hunter, working aimlessly into finding both newfound passion and her gender identity, while Naoto proudly showcased her original gender as she worked diligently with law enforcement], and fight alongside animalistic summons [Bridget with Roger, Naoto with Sukuna-Hikona])
  • Ness (Young yo-yo wielders who are often accompanied by teddy bears)
  • Poison (A battle between popular, transgender fighting game characters that don't appear much in their series)
• Brook vs. Spinal: Skeletal pirates who are both master swordsmen, can harness their souls to perform supernatural feats, and have signature laughs.
• Bruno Bucciarati vs...
  • Alear (Revenant Zombies who act as Universally Beloved Leaders)
  • Satsuki Kiryuin (Antagonists turned protagonists with a blue and white color scheme who leads morally-dubious groups, with the former being a kind-hearted and firmly good mentor to the main protagonist [Giorno] while the latter is a cruel and controlling totalitarian who serves as a rival to the protagonist [Ryuko])
  • Shiver (Antagonists turned protagonists with a blue and white color scheme who are part of morally ambiguous groups, with both of them seeing the protagonists that they were beaten by as meaning well after they're beaten)
  • Trafalgar Law (Members of underground criminal organizations who have the ability of spatial manipulation and protagonists who start as antagonists)
• Bryan Fury vs...
  • Goro Majima (Ax-Crazy criminals who are associated with snakes, are known for their wild cackling, and consistently serve as arch-enemies of noble heroes [Kiryu for Majima, Yoshimitsu for Bryan], with Majima being an anti-hero while Bryan is evil to a fault)
  • Kano (East vs. west fight of cybernetically-enhanced, brutish criminals from fighting games who have an rivalry with a more noble brawler [Yoshimitsu for Bryan, Sonya for Kano])
  • Ryuji Yamazaki (Ax-Crazy criminals who are associated with snakes, fight using brutish physical strikes, appear as consistent rivals against a noble hero [Yoshimitsu for Bryan, Terry and Blue Mary for Yamazaki], with Bryan being and consistently serve as arch-enemies of noble heroes [Kiryu for Majima, and were enhanced in some way [with Bryan being enhanced through technology while Yamazaki was enhanced through dark magic])
• Bubsy vs...
  • Blinx (Failed feline video game mascots)
  • The Cheetahmen^*In the instruction manual, its shown that the kid playing the game, the Action Game Master, can transform into all 3 Cheetahmen. He could use this ability in the fight (Failed mascots known for being terrible games)
• Bugs Bunny vs...
  • Felix the Cat (Both are Cartoon Animal Tricksters that can get anything they need during any situation to either get out of trouble or outwit their enemies)
  • Mickey Mouse (mascots of the Golden Age of Animation)
• Bullseye vs. Deadshot (assassins with Improbable Aiming Skills)
• Bumblebee vs...
  • Charotte (bee-themed superbeings)
  • The Wasp (bee-themed heroines with laser stingers and size-shifting powers)
• Bun Bun vs. Max (killer rabbits)
• Buraki vs. the Warbat (Aggressive, evil kaiju who take the appearance of serpents)
• Byleth vs...
  • Rean Schwarzer (JRPG protagonists, who are teachers at a military academy who have an "ashen" moniker, gain a power up that changes their hair color, have a spiritual connection to another nonhuman being, which gives them the ability to wield a special divine weapon, and almost died during their childhood, only to survive thanks to one of their parents giving them their heart. They also act in a antagonistic role in a spinoff released in The New '20s [Fire Emblem Warriors: Three Hopes for Byleth and The Legend of Heroes: Trails of Cold Steel - Northern War for Rean respectively)
  • Shulk (Heroes of Nintendo-owned JRPGs who wield legendary swords, were born with the purpose of hosting an ancient God within their bodies, are undead, and have time-related powers)
• C-3PO vs. Dr. Zoidberg (The Smart Guys to their teams who are The Friend Nobody Likes)
• Cactus McCoy vs Cereus Peashy (Eponymous cactus protagonists of Flash platformers)
• Cael Cyndar vs. Spyro (Heroic dragons trying to save their species, have a Fairy Companion and possess Elemental Powers beyond the standard fire breathing.)
• Caenis vs. Poseidon (Alternative takes on characters from Greek mythology who fights with a trident and hydrokinetic attacks, have extremely short fuses and a love for combat despite their contrasting personalities [Caenis being a loudmouthed warrior while Poseidon barely even showing emotion], and both eventually died in battle)
• Cait vs
  • Sadie Adler. Wild, reckless Dark Action Girls.
  • Abby Anderson. Bitter young female post-apocalyptic survivors with an affinity for melee weapons.
• Caius Qualls vs. Kevin (Protagonists from JRPG franchises, are members of werewolf-like species [Leymon and Beastmen] who faced persecution by humans forcing the kinds into hiding, are half-human sons of their species' rulers, they never managed to use their werewolves modes until someone they hold dear died, their fathers [Vincent Bridges and the Beast King] were responsible for instigating most of their games conflict)
• Cale Tucker vs. Jim Hawkins (space-faring cartoon heroes)
• Calliope Mori vs. The Undertaker (Death-themed entertainers with supernatural abilities who are among the most well-known figures in their industries)
• Calypso vs...
  • Cosmo/Wanda (Reality-warping wish granters who put everyone in big danger)
  • The Djinn (Reality-warping Jackass Genies with a habit of cruelly twisting wishes against their patrons)
• Camilla vs...
  • Cynthia (Women with long hair who fight alongside dragons)
  • Haru Okumura (Female ax-wielders who were born as the child to a family of high status, betray their fathers, have a bloodthirsty side to them, and team up with a partner in combat [Camilla with her dragon, Haru with her Persona])
  • Minamoto-no-Raikou (Brutally powerful warriors associated with the color purple, show no mercy to their enemies, are obsessive to their loved ones, are willing to murder those that may hurt them even in the slightest, fight with brutally big weapons, can make use of several elements, and are well regarded as fanservice characters that are in constant praise for their beauty even as one-women armies)
• Cap'n Crunch vs. Toucan Sam (Cereal advertising mascots)
• Captain Hero vs. Splendid (Superman parodies from incredibly violent cartoons with questionable morality)
• Captain Jack Sparrow vs...
  • Captain Hook (A battle between Disney's two most iconic pirate captains)
  • Cervantes de Leon (Anti-heroic pirate vs. villainous pirate, both of whom have dealt with supernatural forces at sea)
  • Edward Kenway (Anti-heroic pirates)
  • Gangplank (Infamous, legendary pirate captains who've encountered their fair share of bizarre and strange beings)
  • Guybrush Threepwood (Witty, cunning, and unpredictable pirates who've both fought undead threats)
  • Hondo Ohnaka (Pirates who act wacky while actually being much more dangerous than you'd think, who often manage to get out of tough situations using a combination of genuine intelligence and sheer dumb luck)
  • Indiana Jones (Adventuring, Combat Pragmatist protagonists with nice hats)
  • Joseph Joestar (Playful tricksters who have fought the undead and whose survival is attributed to a bizarre combination of brilliant planning, improvisation, and supernatural luck)
  • Pirate Man (A human pirate vs. robot pirate)
  • Zorro (Wily and supremely skilled swashbucklers legendary for their skills with a blade)
• Captain Pollution vs. Hexxus (Anthropomorphic Personifications of pollution from 90's media with infamously Anvilicious green aesops)
• Captain Qwark vs. Zapp Brannigan (Incompetent space heroes with big egos who're well known for being proud of their bodies, as well as having their moments of being a Jerkass)
• Captain Rex vs...
  • Agent Washington (soldier who turns against the government/organization whom they serve after realizing its true nature through an incident involving a program in their head)
  • Colonel Radec (Gun-wielding commanders with menacing suits of armor, with the former is evil while the latter is heroic)
  • Soldier: 76 (Legendary, masked soldiers who were forced to go into hiding falling the demise of the organizations they worked for)
• Captain Underpants vs. El Chapulín Colorado (Joke superheroes from non-comic media who are a lot more powerful than they first appear)
• Carl and Ada Clover vs. Daki and Gyutaro (Brother–Sister Team consisting of a Knight Templar Big Brother and the sister they puppet to fight)
• Carl Johnson vs. Franklin Clinton (gangster Grand Theft Auto protagonists)
• Cassandra Cain VS...
  • River Tam (Practitioners of Waif-Fu with Combat Clairvoyance)
  • Shang-Chi (Kids born into evil families who rebelled and became heroes)
  • Snake Eyes (Mutant ninjas who were raised by a group of ninjas who were taken in by their birth families later, only to get into conflict with them due to their moralities)
  • X-23 (Young, female Tyke Bombs who use Waif-Fu)
• Catwoman vs...
  • Ada Wong (The defining examples of Dating Catwoman in their respective mediums. Also both Badass Normal femme fatales who are experts of infiltration and can contend with enemies leagues above them in power.)
  • Bandette (Badass Normal and Affably Evil ClassyCatBurglars)
  • Black Cat (Marvel vs. DC fight of female, cat-themed thieves)
  • Puss in Boots (Lovable Rogues who bear a cat theme [Animal Motif for Catwoman, actual cat for Puss])
  • Fujiko Mine (Femme Fatale thieves)
• Cecil Havey vs. Siegfried Schtauffen (Knights who were once Black Knights but later redeemed themselves to become paladins who fought against a reflection of their former evil actions)
• Cell vs...
  • Dark Samus (Hybrid lifeforms that want to assimilate everyone, cyborgs, have the DNA and abilities of their respective protagonists)
  • Evolto (Major antagonists in long-running Japanese series who constantly evolve between forms, desire to evolve into a "perfect" form to destroy all life in the universe, and fight against a group of heroes all connected under some group [the Saiyans for Cell, the Kamen Riders for Evolto])
  • Meruem (Bug-themed Ultimate Lifeforms from shonen animes with massive egos)
  • Omega (Powerful creatures created by evil scientists that modified their bodies, get their future transformations stopped [by Trunks and Zero respectfully] getting force to lay dormant, were awaken accidentaly by the heroes, cause destruction in the search of mechanical beings [the Androids and the Dark Elf] to absorb them, unlock new forms after absorbing their targets, eventually got destroyed only to come back a bit later stronger than before, are arrogant and see themselves above everyone else in the planet, and have the powers to regenerate and several beam attacks)
  • Zygarde (Powerful beings with similar color schemes who can evolve to more powerful forms [including a half-complete and fully-complete/"perfect" form], with the former being a benevolent keeper of balance while the latter is a violent, artificial entity who wishes to spread destruction)
  • AMAZO (A being combining the powers of Dragon Ball's strongest fighters vs a being combining the powers of The Justice League.)
  • Super Skrull (Green-clad extraterrestrial creatures that are a Mix-and-Match Critter of the heroes, becoming an Ultimate Life Form)
• Cell Max vs. Kimeramon (Giant abominations who were created from the DNA of past heroes and villains connected to a planet threatening villain from the past [Cell and Milleniummon], both were unstable however with power overflowing, this caused them to become uncontrollable by the ones who created them)
• Centorea Shianus vs. Tisalia Scythia (female centaurs skilled at fighting with sword, lance, and bow)
• Cerebella vs...
  • Mystique Sonia (female brawlers that wear a Living Hat as a weapon which it attacks using its appendages)
  • Twintelle (Dark-skinned beauty performers from fighting games that fight with an extra pair of arms on their head, Cerbella with her Vice Versa and Twintelle with her ponytail ARMS)
• Cetrion vs. Elraine (Daughters of godlike beings [Kronika and Fortuna] wishing to create the pefect timeline no matter in how debious mean, have siblings that are the complete opposite of them, whom they oppose [Shinnok and Reala respectfully], some of their strongest attacks involed bringing divine lightning upon their enemies [Cetrion's second fatality and Elraine's Indignation Judgment], and got erased from existance after being defeated by the heroes)
• Chakravartin vs. Zanza (Holy yet evil gods who serve as the ultimate Big Bad of their games, who desire absolute obedience and control over all of existence, and manipulate the protagonist along their journey in their mission to mold them into their successor, only for the protagonist to reject them, leading them to decide to wipe out and recreate the universe in order to try again)
• Chaos vs...
  • Kyogre (Sea monsters whose mere presence can cause extreme amounts of flooding and destruction)
  • Zygarde (Powerful monsters who protect the environment with magical might and evolve between multiple forms [including a final, "perfect" form] to fight, with the former becoming a destructive villain following an attack on the race it used to guard while the latter remains a benevolent figure throughout the ages)
  • Dark Samus (Normal creatures, a Chao and Metroid respectively, who were exposed to Chaos and Phazon radiation to become ability-absorbing monsters)
• Charles F. Muntz vs. Chester V (The elderly main antagonists of CGI films. Both were the childhood idols of the protagonists [Carl Fredricksen and Flint Lockwood]. Both search for an important character [Kevin and FLDSMDFR]. And both have their own servants to help them [Muntz's dogs and Chester's Thinkquanauts])
• Charlie Morningstar vs. Hellboy (Anti Anti Christs who prefer to use their demonic heritage for good [Charlie running the Hazbin Hotel to rehabilitate sinners, Hellboy fighting monsters as a member of the BRPD].)
• Chase vs. Vent/Aile (Brown-haired protagonists who wear blue, work for a male dressed in red, and have multiple suits each with different equipment)
• Chat vs. Tetra (Child pirates from long running franchises that fight in unortodox ways an become essential in stopping a world ending threat)
• Cheetah vs...
  • Catra (Female superhumans with a feline motif)
  • Cheetara (Female superhumans with a cheetah motif)
• The Cheetah vs. Dick Dastardly (Cheating racers antagonists associated with dogs)
• Chell vs. Faith Connors (Parkour-practicing fighters with total control over the environment)
• Chibiterasu vs. Chibiusa (Offsprings of goddesses representing a celestial body, with Chibiterasu taking from the sun and Chibiusa after the moon; and both of them using different variations of their mothers powers)
• Chi-Chi vs. Tiger Lily (The Ugly Guy's Hot Daughter who are in a relationship with bombastic, flying heroes and have a bit of a temper)
• Chie Satonaka vs. Mako Mankanshoku (Brunette students with energetic personalities and strength beyond that of your average person and are the Best Friend to major characters and serve as their beacon of light when they're at their worst)
• Chiron vs. The Nuckelavee (Half-human half-horse hybrids from mythology, being a Centaur and Nuckelavee respectively, who are respectively the living embodiments of healing and destruction)
• Chris Redfield vs...
  • Bill Overbeck (Military veterans who specialize in battling undead threats)
  • Kurtis Stryker (Minor officials who fight against supernatural entities)
  • Sebastian Castellanos (Capcom-owned survival horror protagonists)
• Chrollo Lucilfer vs...
  • Necrozma (Power-stealing antagonists with a mainly black color scheme who seek to throw their worlds into chaos)
  • Toichiro Suzuki (Power-stealing, nicely-dressed crime lords)
• Chucky vs...
  • Annabelle (Creepy Doll vs. Perverse Puppet match of unassuming yet deadly spirits who inhabit the forms of toys brought to life using unholy magic)
  • The Leprechaun (Cartoonish horror movie villains)
  • Slappy (Abusive Perverse Puppets who were brought to life using unholy magic and fight against children)
  • Stripe (Pint-sized antagonists that torment their franchises' iconic protagonist [Andy Barclay and Gizmo respectively] and have the ability to create an army [Chucky splitting his soul into other Good Guy dolls and Stripe spawning more Gremlins respectively])
  • William Afton (Serial killers who are trapped in a non-human body of a normally innocent object [Charles Lee Ray/Chucky being in the body of a doll while William Afton/Springtrap is in the body of an animatronic])
• Cinder vs. Human Torch (hot-headed young men who have pyrokinetic powers and got them through scientific origins [genetic experimenting and cosmic radiation]. They also did questionable deeds for the thrill of it and are members of well-known organizations [Ultratech and the Fantastic Four], where they endlessly annoy others with their remarks)
• Claude von Riegan vs...
  • Atalanta (Skilled archers who despite being born royalty faced discrimination in the past [Claude for his race and Atalanta for her gender], despite being looked down upon they also have many suitors, have no interest in the gods of their worlds [Claude disliking blind faith in gods while Atalanta went against Artemis's wishes], and went in a fight against those they once called friends due to their strong beliefs)
  • Joseph Joestar (Charming and cunning heroes of noble heritages [Claude having Almyra's royal bloodline and Leicester's leading duke while Joseph is a Joestar], have a down-to-earth personalities and strong-willed mothers [Tiana von Riegan and Joseph Joestar], posses unique abilities due to their bloodlines [Claude having the Crest of Riegan that let's him bear Failnaught and have unique combat techniques, while Joseph is a Hamon born user and eventually a Stand user], they had to leave their parents abd live with their grandparents, both fought racism while traveling to foreign countries [Claude wanting Fodlan to be more open and mix itself more with its neighbours to diminish racism, while Joseph defended and become friends with Smokey Brown and fought Nazis in Mexico], both travel in order to help someone older they truly respect, meet their combat teachers while in their travels with said meetings play in completely opposite ways [Claude meets Byleth in Remire Village while in the Adrestian Empire, and Byleth helps him; meanwhile Joseph meets Lisa Lisa in Venice and she immidiately antagonizes him at first], said teachers would accompany them beyong their combat training, frequently fight monsters during their adventures, and led to them fighting groups who use ancient artifacts to enslave people they into monsters [the Crest Stonea and the Stone Mask], and in battle they're extremely tactical and calculating but while they don't hide how deceptive they can be, they refuse to use tactics they deem to cruel)
• Claptrap vs. Emerl (Childish, amnesiac robots who are failed attempts to make ultimate weapons, joined forces with a team of heroes before they were attempted to be used once more as weapons by antagonists, can copy the abilities of others, go haywire at some point in their stories, have similar color schemes, and have Evil Counterparts)
• Clementine vs...
  • Arya Stark (Girls who have lost their families [Clementine's parents were turned, Arya's parents were murdered on two separate occasions] and have grown strong to survive on their own. Incidentally, both have been featured in games made by Telltale)
  • Ellie (Girls surviving a Zombie Apocalypse)
• Coco Bandicoot vs. Futaba Sakura (Teenage girls who are skilled hackers)
• Cooler vs. Vrak (Aliens who are high ranking members of groups [Cooler Force and War Star] which work for a even bigger empire [Emperor of the Universe and the Armada Alien Royal Family], are sons of cruel space Emperors [King Cold and Emperor Marvo] and both have a brother who were spoiled [Frieza and Prince Vekar] who they also deeply hate because of their spoiledness, both would come down to earth and start fighting the strongest fighters on earth [Z Fighters and Power Rangers], they would die in their strongest forms [Finale Form Cooler and Mutant Armor] and they'd die to the protags new super forms [Super Saiyan and Super Megaforce], but after they'd die they would be resurrected in new cyber forms)
• Colgate/Minuette vs. Time Man (both can slow down time and the former behaves like her Minty Fresh Adventure counterpart)
• The Colossus of Rhodes vs. The Sleeping Giant of Del Mar (Giant non-organic first opponents fought in sequels. They only appear at the beginning but get the protagonists crushed upon defeat, kickstarting the rest of the plot)
• Commander Shepard vs...
  • Noble Six (Space marines who fight alien invaders and can be male or female)
  • Pathfinder Ryder (A duel between two Mass Effect protagonists separated by galaxies and centuries)
  • Star-Lord (Leaders of space-fairing teams consisting of characters from multiple different species who fight to protect the galaxy)
• Commissioner Gordon vs...
  • Kaoru Ichijo (Badass Normal police officers who are reliable allies to a masked hero)
  • Nick Fury (DC vs. Marvel fight of leaders of human forces who aid heroes)
  • Phil Coulson (DC vs. Marvel fight of leaders of human forces who aid heroes)
• Conquest vs. Nappa (Humanoid aliens who are proud of their race's history of bloodshed and enjoy hunting down and destroying those weaker than them)
• The Copycat vs...
  • Boki Lamira (cats who can copy powers)
  • Delsin Rowe (power copiers)
  • Streaky the Supercat (superpowered cats who got their powers from space-based Applied Phlebotinum and are owned by women)
• Corvo Attano vs...
  • Booker DeWitt (Former agents of the law who later fight against it who protect a woman with markings on their hands)
  • Ezio Auditore (Hooded assassins with supernatural powers)
• Corrin vs...
  • Euden (Sword-wielding princes from fantasy games published by Nintendo who can transform into dragons and have issues regarding their families, mainly that they aren't true members of them by blood)
  • Fou-Lu (White-haired royals with the power to transform into dragons)
  • Rain (People who were born of nobility but became separated from them soon after birth, wield water as their primary means of attack, were the main player in a civil war, and both have an unusual heritage which puts them above others [Corrin being half-dragon and Rain being a demigod])
• Crono vs...
  • Cress Albane (Protagonist of JRPG games that released in 1995 for the SNES that consist of them time traveling in order to save the world)
  • Erdrick (Protagonists of RPGS made by Square Enix who wield swords and were designed by Akira Toriyama)
  • Lucina (Time-traveling, sword-wielding RPG protagonists)
  • Terra Branford (Protagonists of popular, SNES-era RPGs made by Square Enix)
• Copy-X vs...
  • Elysium (Copies the former being mechanical, while the other is magical of great heroes intended for the side of good but turned evil [X and Sophitia Alexandra], see themselves as saviors, intend to make a better world but through the use of violence, and have abilities that copy several other fighters [Copy-X having X's attacks and Elysium being a mimic fighter])
  • Hades Izanami (Rulers in their respective universe with a corrupted government [Copy-X ruled over Neo Arcadia wit help from the Eight Gentle Judges and Four Guardians in which Reploids were used more as tools than equals, and Izanami ruled the NOL which in turn ruled every Hierarchical City], fought against a resistance who wanted to overturn said government, are clones of someone with good intentions for the world [X and Saya], and they were believed to be the main antagonist, until it was revealed that they were brainwashed pawns to be used as expendable minions)
• Cthulhu vs...
  • Oryx The Taken King (Powerful gods who force creatures to insanity [even to a loss of willpower in Oryx's case])
  • Phelphor (Monsters with Mind Control powers who originate from the sea)
  • Shuma-Gorath (Basis vs. homage fight of green eldritch horrors)
• Curly Grace vs. Rebecca (Hyper active cybernatic women [Rebecca's a cyborg] with love for big guns which they use by rushing into the enemy)
• The Cyberdemon vs...
  • The Nemesis T-Type (Large and brutish monsters with mechanical enhancements, including powerful rocket attacks, who serve as memorable antagonists in shooters)
  • Raum (large, powerful, horned demons wielding BFGs)
• Cyborg vs...
  • Android 17 (Once ordinary people who have had their body parts replaced with cyborg implants)
  • Kamen Rider Stronger (Once ordinary, teenage football players who became superheroic cyborgs)
• Cyclops vs. Joe Shimamura (Stoic, heroic and compassionate field leaders of costumed superhero teams who endured emotional trauma, loss and tragedy at a young age. Both are also burdened with great powers that they couldn't control but learned to use them for the greater good even with the experience with prejudice and injustice from their mixed heritages. Both also have a long history rivalry with a hot-headed teammate who is a lone wolf of the team, but ultimately have mutual respect for them [Wolverine and Jet/Cyborg 002, respectively])
• Cynthia vs...
  • Margaret (Powerful female commanders of monsters who serve as guides to the protagonist)
  • Tsunade (Female mentor figures with blonde hair who are highly celebrated figures in their regions)

D-F

• Dabi vs...
  • Iori Yagami (Moody, abrasive rivals of pyrokinetic protagonists who use uniquely-colored flames)
  • Mordred (Rejected children of great heroes who seek revenge against them)
  • Noob Saibot (Edgy, vengeful antagonists who are dark-reflections of major protagonists who are their siblings)
• Daenerys Targaryen (and Drogon) vs...
  • Imrik (and Miniathnir) (Blonde royal Dragon Riders)
  • Kairi (Glass Cannon females with immense power at the cost of little to no defensive training)
• Dagahra vs. Gyaos (Bio-engineered kaiju created to serve ancient civilizations only to be responsible for their downfall, only to awaken in the modern day to fight a kaiju deemed to be Earth's protector)
• Daisy vs. Alena (Two princesses with orange hair, regarded as tomboys with extroverted personalities and tough demeanor, both proving they're stronger than they look, are quite competitive in nature, have shown to be short-tempered, stubborn, impulsive and unafraid to speak their mind, yet they're extremely polite, kind and friendly people with great care for their kingdoms, they prefer not to be proper or poised as their appearance and royalty status though they do like accesory, and love taking on big challenges)
• Damian Wayne vs. Hit-Girl (sociopathic sidekicks)
• Dan Kuso and Drago vs. Ginga Hagane and Pegasus (Hot-spirited teens who battle with toys that transform into mythological creatures)
• Dante Alighieri vs...
  • Alice Liddel (Twisted adaptations of heroes from classic literature)
  • Death (Protagonists from religiously-themed hack-and-slash video games who wield scythes, fight demons, and have markings on their bodies representing their sins, with Dante already having fought a version of Death in his own game)
• Dark Carnage vs. Xeno Kid Buu (Alternative and more powerful version of hateful and insane monsters that've een deemed evil incarnate, they want nothing more than causing chaos and havoc, they're both goo-like creatures, have heroic counterparts who've tried to stop them [Venom and Fat Buu], commited mass murder upon their worlds, and would use an artifact [Scorn's codices and the Dark Dragon Balls] to transform themselces into their most powerful forms)
• Dark Kahn vs. Ultron Sigma: (Fusions of a Comic-book villain and a Video-game villain)
• Dark Magician Girl vs. Gardevoir (Popular, feminine monsters from monster-collecting series who fight using dark magic)
• Dark Pit vs...
  • Luea (Dark-colored, designed to mirror white-colored heroes, and were rivals to said heroes before becoming allies with them. Luea also grows wings herself)
  • Lillith (Artificial clones of the main character who acts as the main counterpart)
  • Nedrick (Black-wearing, emo clones (although it’s eventually revealed the Nedrick is actually the original) who act as Foils for the naive and optimistic main hero and started out as one of the main villains of their respective stories, but eventually become anti-heroes who would be essential allies to the hero)
• Dark Prince/Satan vs...
  • Remilia Scarlet (Extremely powerful yet generally chill unholy beings)
  • Yukari Yakumo (Powerful beings who act as the de-facto Big Bads of their series and have both friendly and hostile relationships with a female mage who acts as the main protagonist)
• Dark Samus vs...
  • Deoxys (Both are parasitic alien invaders born from an infectious space substance that experienced significant mutations who have a connection to meteors)
  • SA-X (Evil Doppelgangers of Samus Aran)
• Darkwing Duck vs. Paperinik (Superheroic ducks with bad luck)
• Darth Maul vs...
  • Aatrox (Inhuman, sword-wielding men with demonic appearances and red and black color schemes, who are a part of a group of former heroes who were corrupted by power, and were once a larger group a thousand years ago, but have now dwindled to only a handful of people. Both were defeated in battle and isolated, with said isolation causing them to go insane, but were eventually saved from their isolation by an outside force and now seek revenge against the people they blame for their downfall)
  • Byakuya Kuchiki (Antagonistic swordsmen who serve as rivals to a major protagonist, are older brothers to other characters [with Maul's sibling being evil while Byakuya's sibling is good], and members of groups that have existed for centuries)
  • Judge Gabranth (Elite enforcers of villanous groups [the Sith and the Archadian Empire] whose lives are defined by the sheer hatred in which they live upon, they fight using double-bladed swords which are comprised of two separate blades. This hatred coming from someone [Obi-Wan Kenobi and Basch Fon Ronsenburg] whom they swore to make their lives a lives a hell, yet those two always managed to put their lives back together in pursuit of a new and rightous purpose. They were seeing as more than disposable pawns by the Emperors they followed, and they had one big positive influence on one individual they rightfully care for [Savage Oppress and Larsa Solidor])
  • General Grievous (Ruthless Sith enforcers foreshadowing Darth Vader with more exotic fighting styles)
  • Goro Akechi (Laser-blade wielding antagonists who betrayed both the protagonist and their villainous employer, have a red-and-black color scheme, and were originally thought to have died before returning in future entries for their series)
  • Grøh (Vengeful, sword-wielding Handicapped Badass who work for organizations who wear dark clothing)
• David Martinez vs...
  • Adam Jensen (Mechanically-modified protagonists from prequel entrants in their series)
  • Shotaro Kaneda (Jacket-wearing protagonists from cyberpunk media who are rebels who live at the edge of society, repeatedly lost loved ones in tragedies [including their parents and fellow gang members], wield mechanical weaponry known for its speed [David with his Sandasvistan implant, Kaneda with his laser rifle], and fight against both modified humans and corrupt corporations to protect their criminal found families)
• David Xanatos vs. Iron Patriot (Genius and extremely rich masterminds who are CEOs of companies and fight with suits of armor designed to resemble a hero of their world)
• Davy Jones vs. Viego (Sword-wielding undead villains who hold a high-ranking role among the dead, who were once normal humans until the loss of the woman they loved led them down a villainous path, which resulted in an event that upset the system of death in their respective worlds. Both suffered a stab wound to the chest that plays a part in their undead nature, and both carry around a music box that they use to remind themselves of their lost love, and also features in their respective leitmotifs)
• Death vs. Prometheus (Scythe users who can summon fire)
• Deathwing vs...
  • Alduin (two draconic destroyers)
  • Fatalis (Extremely dangerous and wildly feared dragons who seek to destroy mankind)
  • Kaido (Extremely powerful and destructive dragons who seek to destroy civilization)
  • King Ghidorah (Ancient dragons who are highly destructive, capable of wiping out all life on a planet and their very presence has been shown to cause catastrophic events and alter the environment around them)
• Death Jr. vs. Kid Dracula (Quirky eponymous sons of Public Domain Characters)
• Debora Briscoletti vs. Minerva Orland (Dominating women with high reputations and praise in their cities, were raised by politically powerful fathers whose upbringing shaped their personalities [Debora's father was nice and caring causing her to be spoiler, while Minerva's was cruel and abusive, making her ruthless], are descendants from legendary bloodlines, fight in close combat, can use magic to make barries, shot beams and drain energy, and were fine using others for their own gain yet they have some level of morality that grows as their stories progresses)
• Dee Dee vs.
  • Candace Flynn (The meddling older sisters of young Mad Scientists who always try to interfere with their younger brother’s inventions for opposite reasons [Dee Dee wants to get involved with Dexter’s experiments while Candace doesn’t want her brothers inventing things and tries to stop them], which leads to them usually causing the issue for the episode)
  • Johnny Test (Destructive Dumb Blondes who make life hard for their redheaded super genius siblings)
• Delsin Rowe vs...
  • Akari Sakura (Successors of powerful heroes)
  • Kamala Khan/Ms. Marvel (Next-gen heroes who act as the successors of powerful heroes while inheriting the previous title despite being apart of different races/cultures)
  • Vent/Aile (Successors of powerful heroes who switch back and forth between several power sets)
• The Demi-fiend vs. Laharl (Powerful, demonic protagonists from Japanese RJPG series who command other unholy beings, with the former being a mute character from a grim, serious series while the latter is a talkative character from a light-hearted, comedic series)
• Demitri Maximoff vs...
  • Arystar Krory III (Powerful, romantic vampires)
  • Dabura (Rulers of demons)
  • Slayer (Fancy vampires in fighting games)
• The Demoman vs...
  • Junkrat (Mentally-unstable bomb-users from rival team-based shooters), with the former using traditional weapons while the latter invented their own)
  • Soap MacTavish (Scottish game soldiers who specialise in explosives)
  • The Scotsman (Boisterious and unpredictable Scotsmen)
• Denji vs...
  • Kaiman (Anti-heroic protagonists from modern manga/anime set in fantasy Crapsack Worlds plagued by demons with unique heads [at least as the Chainsaw Devil for Denji] who take no issue with eating their opponents)
  • Ken Kaneki (Anti-heroic protagonists from manga/anime who are teenagers that transform into demons to fight other demons, to which they take no issue with consuming them)
  • Mercury Black (Two characters who losed part of their body,was recruited by attractive,but sinister woman and killed their own fathers)
  • Yuji Itadori (Once ordinary orphaned boys from Shonen Jump series who merged with a powerful demonic entity before being personally recruited by a powerful warrior [Gojo for Yuji, Makima for Denji] to join their demon-killing organizations)
• Destoroyah vs...
  • Iris (Powerful, sadistic kaiju that are the antithesis to their enemies, serve as the final antagonist of a film series, constantly evolve, and are symbolic of the hubris humanity faces by fighting kaiju)
  • Legion (Insectoid kaiju who have multiple forms and serve as challenging opponents to their kaiju enemies)
• Detective Pikachu vs. Paramount Sonic (Movie versions of popular video game characters with electric abilities who go up against mad scientists while partnered with a human)
• Dexter vs...
  • Jimmy Neutron (Young Mad Scientists from rival networks)
  • Phineas and Ferb (Young Mad Scientists from rival networks who have a meddling older sister and an exotic pet that secretly fights crime)
• Dexter Morgan vs. Shun Uruma (Two brutal vigilantes who, after being trained by foster parents to fight after a childhood of abuse, went on to find passion in torturing and killing those who hurt others)
• Dhalsim vs...
  • Muhammad Avdol (Calm, peaceful, strategic fighters who have pyrokinetic abilities, travels across the world to face an evil mastermind with the desire to rule over the world who boast too much of their powers [Dio and M. Bison, respectively], and have a friendly relationship with the main character [Jotaro and Ryu, respectively] that they help with their "evil power" problem [Avdol frees Jotaro from prison and activates Star Platinum, while Dhalsim helps Ryu with the Satsui no Hado])
  • Zenyatta (Monks who fight despite their pacifistic nature who can levitate, with the former being a human who uses magic while the latter is a robot who uses technology)
• Dhaos vs. Igniz (Blonde-haired final bosses from long-running videogame franchises that specialize in Instant Runes to release brutal Kamehame Hadoken attacks, with Dhaos being a deity while Igniz thinks he's a deity)
• Diablo vs...
  • Malebolgia (Nightmarish rulers of Hell who are equilvents to Satan under different names)
  • Mephisto (Red-skinned rulers of Hell who are equivalents to Satan under different names)
• Diane vs...
  • Cassie Lang (Giants who frequently ran away from home due to their disdain for how they were being raised, who lost their greatest mentor figure and ended up joining a somewhat contentious team of fellow heroes following some troubles with the law)
  • Sakura Haruno (Action Girls from Shōnen manga, who rely on their Super-Strength in combat)
  • Shantae (Female heroes with long hair who use Magic Dances)
• Diaochan vs. Kamen Rider Gaim (Dancers with strong historical references who manage their ways through territorial disputes and a great invasion. Both their stories revolve around the theme of great sacrifice being necessary to obtain hope (However, Gaim despises this ideology, and actively and very flashily seeks to destroy this system from the outside, while Diaochan, while openly disliking this rule of life and the war that follows, still manipulates it from the inside for her own gain.) Both also fight with a handful of supernatural abilities, but mainly with swapping between a bunch of different historical weaponry on the fly)
• Diavolo vs...
  • Chrollo Lucilfer(Leaders of criminal organizations with devil related motifs. Due to the circumstances of their upbringing, neither of them have any records about them, and their identity is shrouded in secret. Both have an ability that allows them to predict the future. As a contrast, Diavolo is extremely egotistical and believes the world should revolve around him, while Chrollo doesn't see himself as any more important than any other member of his troupe)
  • Kai Chisaki - Overhaul (Leaders of organized crime empires who want to boost the power and influence of their organizations until they are essentially the shadow emperors pulling the strings behind everything. Both are also horribly Abusive Parents^noteWhile Overhaul isn't Eri's biological father, he was her primary caretaker, and he is referred to as her father multiple times)
  • Mr. Negative (Mob bosses with mysterious pasts that have two personalities, one being good aligned and unaware of the other personality, while the other is violent and aware of the other personality)
• Dimentio vs...
  • Fawful (Dragon ascendants from Mario RPGs)
  • [Final Fantasy VI Kefka Palazzo]] (Monster Clown RPG villains who are Godhood Seekers that betray the villain they were pretending to be loyal to.)
  • Magolor (traitors from Nintendo video games that are among the most popular in their series who seek ultimate power over the universe)
  • Mephiles the Dark: (Omnicidal Maniacs and Hero Killers from Darker and Edgier installments of rival franchises)
  • Shaco (crazy harlequins)
  • Skull Kid (Playful yet chaotic and highly destructive villains from Nintendo video games that are among the most popular in their series with a masked aesthetic)
• Django vs. Rapunzel (Blithe Spirit protagonists with solar-based powers who were separated from their parents)
• Doma vs. Ayaka Kamisato (Warriors that were granted their powers by powerful godlike entities [Muzan for Doma and Celestia for Ayaka], both fight with ice base powers. In contrast Doma was born in a horrific family in which they killed eachother, while Ayaka was born from a happy and trustworthy family)
• Dr. Finitevus vs. The Spot (Once-noble scientists who were caught in a radioactive explosion while testing on a hero, were bleached white, gained the power to create interdimensional portals, and became unrepentant villains)
• Dr. Gero vs. Gate (Scientists that isolated themselves in caves in order to conduct their experiments, went insane, modified their bodies in case they need to fight, created an army of robots to kill the heroes, and have barriers and energy absortion techniques)
• Doctor Octopus vs. Mistral (Cybernetic antagonists with extra sets of arms)
• Dominic Hargan vs. Rocksteady (Rhino-themed combatants)
• Dominic Toretto vs. Speed Racer (Drivers who are brothers who disappeared and returned after a long time and performs car stunts that breaks the laws of physics)
• Donquixote Doflamingo vs...
  • Hisoka Morow (Extravagant, manipulative antagonists who use string-based weaponry)
  • Jolyne Cujoh (Inventive manipulators who weaponize string, with the former being an antagonist while the latter is a protagonist)
  • Nui Harime (Cold-hearted, Ax-Crazy criminals with pink outfits who have the ability to manipulate string and killed someone close to a protagonist [Doflamingo killing Trafalgar Law's idol, Corazon while Nui killed Ryuko's father])
• Doppo Kunikida vs. Kento Nanami (Blonde-haired, glasses wearing characters from long-running supernatural action manga, who serve as a secondary mentor figure to the teenage protagonist who is the vessel for a powerful, but uncontrollable monster. Both are a part of a group of people with special abilities that are unique to almost everyone, are very meticulous and serious to the point of it being comical, and are a common victim of annoyance to their gadfly of a coworker with a powerful ability)
• Dormammu vs...
  • Gargos (All-powerful interdimensional conquerors who have plans to conquer Earth)
  • Jedah Dohma (Powerful galactic demons who seek to conquer the universe with their immense power and cunning manipulative minds)
  • Trigon (Powerful demon lords from rival comic companies)
• Doomfist vs...
  • Sundowner (Bald cyborg terrorists who lead an evil private military organization and believe war will make humanity stronger)
  • Killmonger (Afrofuturism-inspired terrorists who use high-tech gadgets)
  • Vi (Power Fist-wielding Blood Knights of contrasting alignments)
• Double vs. Envy (Shapeshifting monsters that take comfortable apperiences to hide the monsters, took the appereance of several main characters [Double to take their moves and Envy to trick them], and are play big roles in kickstarting their franchises plots)
• Dracula vs. the Witch-king (Undead maintained by demonic forces)
• Dr. Fox vs. Eddy (animated inventor foxes)
• Dr. Nefarious vs. General Grievous (Powerful yet cowardly mechanized aliens who command robotic armies, with the former adores it to the point he wants everyone to be robots while the latter hating his cybernetic state)
• Dr. Neo Cortex vs. Dr. Zomboss (Literally Big-Brained Mad Scientists that command massive armies)
• Drizzt Do'Urden vs. Malus Darkblade (Dark elven adventurers who have their own book series)
• Duke Nukem vs...
  • The Heavy (Gun-wielding comedic characters from first-person shooters)
  • The Postal Dude (Protagonits of western shooters who are crude, humorous heroes who use a variety of firearms, wear sunglasses, are voiced by the same person and manage to go toe-to-toe with normally serious threats, with Duke Nukem being beloved in-universe while the Postal Dude is hated in his world)
  • Serious Sam (Humorous gun-wielders from western shooters)
• Dunban vs...
  • Auron (Powerful samurai from RPGs who fight with only one arm, failed to save those they cared for in the past, and serve as a father figure to a blonde-haired protagonist)
  • Shanks (World-famous heroes who practice swordplay with only one working arm)
• the Duck Avenger vs. Duck Dodgers (famous cartoon ducks taking a sci-fi superhero-themed level in badass)
• D. Va vs...
  • Elegg (Female operatives of defense companies [with one using a mech, while the other is an android] who joined their groups from non-combative positions [D.Va being originally a competitive gamer while Elegg is a mechanic], and are associated with video game series released in the 90s [with D.Va being stated to be a fan of StarCraft while Elegg is a mega-fan of Boom, a clear riff on Doom])
  • Gaige (FPS action girls aided by powerful robots)
  • Mechanica (Characters from PvP multiplayer games who are girls that pilot Mini-Mecha)
  • Tron Bonne (tech-savvy girls who drive a Mini-Mecha)
• D'Vorah vs...
  • Poison Ivy (Villainous female commanders of a normally unassuming species [bugs for D'Vorah, plant for Poison Ivy] ho seek to bring glory to their minions)
  • Q-Bee (Villainous humanoid insects from fighting games who are the queens of their hives)
  • Sadira (Villainous fighting game characters who are bounded to and attack with insects)
• Dynamite Headdy vs...
  • Chuck D. Head (protagonists of Sega Genesis platformers who can throw their heads at enemies)
  • Plok (Platformer protagonists with red and yellow color schemes who fight by throwing their own body parts)
  • Ristar (another Genesis platformer protagonist who can aim short-ranged attacks in any direction)
• Eddie vs...
  • Evil Ernie (Villain Protagonists that draw their power from creativity and expression with have similar designs, with the former starting as a cosmic entity but becoming mortal while the latter is a mortal that became a Lovecraftian horror)
  • The Guy (Old school vs. New school battle of Metal Band Mascots who are regularly seen on the covers of their albums)
  • Vic Rattlehead (Recurring mascots of metal bands [with the former being British and the other American] who are often seen in related covers/media under various roles doing evil [or at least morally questionable] deeds)
• Edmond Dantes vs. Xiao (Green-colored protectors to the protagonists of their respective games [Ritsuka for Dantes, The Traveler for Xiao] that can also be summoned by players. Dantes and Xiao also possess powers with some ties to dark powers [Dantes is an Avenger-class Servant, Xiao is a Yaksha.])
• Ed, Edd, and Eddy vs. Yakko, Wakko, and Dot (Cartoon trios known for causing pranks, using cartoon logic and physics, and generally not being very smart)
• Edward D. Teach vs. Brineybeard (Similar looking pirates that fight unortodox looking enemies with supernatural boats and simp for non-human women)
• Eikichi Onizuka vs. Taiga Fujimura (Eccentric teachers with morally grey backgrounds [Onizuka was a gang leader, Taiga is the daughter of the yakuza])
• Elaina vs. Frieren (White haired mages on wandering adventures, spending time in the towns they visit to deal with random problems; both also have someone who is/was completely smitten with them [Saya/Himmel], even if they were disinterested)
• Elisabeth Báthory vs...
  • Athena Asamiya (Pink-haired idol singers with special powers that constantly deal with world-ending situations)
  • Rise Kujikawa (Idol Singers that make use of their musicial skills to attack [Elisabeth cauing soundwaves by singing and Rise healing wounds], were bosses prior to joining the hero's party, and have severe worries to their future selfs)
  • Squigly (Non-human with strong fascination for singing that sadly can't perform it properly [If Elisabeth sings to loud she'll cause a soundwave, and Squigly has her mouth sewn shut], have strong associations with dragons [Elisabeth is part dragon while Squigly fights alongside Leviathan a dragon-like creature], and both referenced Capcom franchises [for Elisabeth is Ghosts 'n Goblins and Street Fighter II for Squigly])
• Ellen Ripley vs...
  • Ash Williams (Sci-fi vs. magic fight of iconic horror movie survivors who fight against an evil species)
  • Burt Gummer (Unexpected heroes who fight against a race of vicious, eyeless monsters that have multiple life stages through powerful weaponry and die in a Heroic Sacrifice by taking a queen of the species off a cliff)
  • Sarah Connor (Iconic sci-fi thriller movie protagonists who are female, fight against an evil species, and protect a child that dies anyway)
  • Sho (Sci-fi protagonists who fight against aliens that infect humans to reproduce)
• Elliot Daniel Dunkel vs. Ranma Saotome (Martial artists who undergo involuntary Gender Benders)
• Elsa vs...
  • Everest (CGI ice users designed with girl power in mind and near the end of the first half of the 2010s)
  • Ice King (Extremely powerful ice magic users)
  • Katarin Bokha (Winter Royal Ladies who hail from a European-inspired Fantasy Counterpart Culture, reside in their own ice palaces, and have unique mounts [Elsa has the Nokk while Katarin can ride both War Bears and her own personal Ice Sleigh)
  • Kula Diamond (Female cryokinetics who defied their destiny [Elsa originally defying her royalty status as Kula denied her status of a minion of NESTS)
  • Lord Fredrik (Royals who froze the protagonists' home turfs over)
• Emet-Selch vs...
  • The Jailer (East vs. west fight of two cosmic-level villains from two of the most popular MMORPGs available today, whose storylines ran at around the same time)
  • Master Xehanort (Big Bads from from Square Enix RPGs that are powerful sorcerers who lead organizations where members wear black hoods [The Ascians and Organization XIII], and become threats to multiple worlds because of the machinations of the GreaterScopeVillains [Fandaniel and Meteion for Emet-Selch and Luxu and the Master of Masters for Xehanort])
• Emilie "Lili" De Rochefort vs. Karin (Rich Bitch rivals to female protagonists from fighting games, with Lili being friends with her rival while Karin is still hostile to hers)
• Emma Millstein vs. Lulua Frixell (Purple haired adopted trainee mages from long running JRPG games who inherit a great responsibility to protect those around them)
• Emperor Palpatine vs...
  • Diana (Have black as their primary color, can both use Force Lightning, and are the masters of the Dark Side)
  • Lord Voldemort (Super powerful Hitler stand-ins)
  • Master Xehanort (Evil Old Folks who're the masters of the Dark Side, and are their respective series' Big Bad)
  • Senator Armstrong (Super-powered Senators who both desire to become head of state, and who engineer a war to further their ambitions)
• Endeavor vs...
  • Fire Lord Ozai (Powerful pyrokinetics who abused their sons to make them into strong warriors, with the former eventually redeeming himself and reconciling with his son while the latter never redeems himself and remains as a heartless, cruel figure)
  • Vinsmoke Judge (Abusive dads who attempted to turn their own children into Tyke Bombs)
• Enel vs...
  • Electro (Villainous electrokinetics)
  • Larxene (Arrogant, villainous electrokinetics)
  • Phosphora (Evil electrokinetics, the former a god wannabe who never redeems himself while the latter is an actual god who eventually does redeem herself)
• The Engineer vs...
  • Sandy Cheeks (Texas-born inventors with experience in fighting)
  • Symmetra (Support characters from team-based shooters that specialize in building sentry units)
  • Torbjorn (Support characters that specialize from building sentry units from rivalling team-based shooters)
  • Marina Ida (Inventors with experience in fighting who value support more than anything else)
• Enrico Pucci vs...
  • Kirei Kotomine (Sinister Ministers obsessed with achieving esoteric dark goals voiced by Joji Nakata)
  • Malos (Affably Evil Big Bads who were influenced by godhood-seeking villains and are the biggest threats to their universes)
• Enterprise vs. Tomoe Gozen (Archers recognized for their military achievements [Enterprise is the strongest Eagle Union carrier while Tomoe Gozen is the most famed female warrior of the Heian period and general Yoshinaka's strongest warrior], held extreme hatred against the enemy that took down their families, they don't enjoy battle despite being one-women armies, have they power to increase their power and defense, and there's sci-fi vs magic theme between them)
• Epsilon-Eagle vs...
  • Gunstar Red (Run-and-Gun protagonists with a decent health bar from Treasure-developed games)
  • Mighty Goose (Cybernetic birds starring in run-and-gun games)
• Erdrick vs. Alis Landale (Legendary RPG protagonist originating from opposing consoles [the NES and the Sega Master System], their journeys marked an epic saga in which their descendants would continue to fighy forces of evil, both games share a similar first person battle system, they both set out on their adventures after the death of someone dear to them, their arsenals though simple due their proper functionallity [swords and shields mix with magic spells])
• Eren Yeager vs...
  • Copen (Morally dubious protagonists who desire to destroy an entire race due to a member of them killing one of their parents)
  • Ken Kaneki (Anti-Hero protagonists who seek to create a better world for everyone, but whose mental instability causes them to become more and more of a danger to those around them, culminating in them transforming into giant monsters whose danger forces both sides of the story's conflict to team up to stop them)
  • Lelouch Lamperouge (Anti-Hero protagonists who are the leaders of revolutionary groups, killed their father for their power, "pilot" giants, betrayed their fellow protagonists, caused horrific acts of bloodshed to unite the world under their cause, and were killed by a childhood friend)
  • Optimus Prime (Movie) (Nominal Heroes who are infamous for their extremely violent tendencies to the point of committing outright war crimes)
  • Shockwave (IDW) (Greater-Scope Villain responsible for instigating the events of their own series via a Stable Time Loop)
  • Ultraman Tiga (Teenagers who transform into massive titans)
  • Wander (Extremely determined teenagers fighting titans)
  • Yuichiro Hyakuya (Teenage protagonists from post-apocalyptic anime/manga series who seek vengeance against a species who killing people close to them, are members of a specially-trained military branch, use specialized weaponry to fight monsters, can transform into more monsterous forms, and eventually turn on humanity to achieve their dream of freedom at the cost of threatening the world)
• Eric Cartman vs...
  • Bart Simpson (Both are kids from adult cartoons that are known for their Troubling Unchildlike Behavior)
  • Master Shake (Main characters from animated adult shows that are cheaply animated on purpose who are greedy, narcissistic assholes and have committed several atrocities throughout their series. They only help people if it benefits them and have even done terrible things to their friends, such as manipulating the naive character [Butters and Meatwad], but they still put up with them despite it)
  • Porky Minch (Nefarious, chubby children whose archenemy is their neighbor whose the same age as them and have a history of taking control of super-natural beings for their own gain)
  • Roger Smith (Protagonists of adult cartoons)
  • Stewie Griffin (Two of the most iconic Enfant Terrible characters in cartoon history who have committed massive crimes despite their young age and have a complicated relationship with their mothers)
• Erron Black vs...
  • Cad Bane (gunslinging bounty hunters with a western motif)
  • Cole Cassidy (Video game gunsligers with mixed morals)
  • The Last Kusagari (Masked gunslingers who fight with a sword and revolver(s))
  • Mercury Black (Badass Normal mercenaries named "Black" who works for antagonists and killed their fathers)
• Etna vs. Hilda (Human looking demons that act as the babysitter the soon to be new Demon Lord in honor of tbe previous ones which they admire, they're powerful enough to be considered high level demons, and both experienced memory lost. In contrast Etna is pretty loudmouthed and sometimes she hates her job, while Hilda is proud of it and acts as a proper maid and babysitter)
• Etrigan vs...
  • Devilman (Humans who bonded with demon warriors in order to protect their homes from other demons, with the both demons are highly respected among their kind due to their power and having violent tendencies while they are kept under control thanks to their human sides, who use their powers for good)
  • Hellboy (Heroic demons from comics)
• Euden vs...
  • Anne Boonchuy (Teenagers who go on a grand adventure after they get separated from the ones they are closest to [Sasha and Marcy for Anne, Zethia for Euden], gain new loved ones as soon as their adventure started, spend their adventures trying to reconnect with the ones they grew apart from [Anne tries to reconnect with her friends while Euden tries to reconnect with his siblings], gather an army in an attempt to overthrow a king, possess a super-powered state that changes their hair color, and have their bodies destroyed at the end of their journeys before they were copied)
  • Daenerys Targaryen (Young royals who free people from tyrannical rule as they slowly gain people for their army and tame dragons to utilize their power)
  • Gran/Djeeta (Sword-wielding protagonists who befriend dragons from fantasy-themed mobile games from Creator/Cygames)
  • Mordred (Homunculi created using magic who are the child of powerful rulers who have their kingdom plunged into darkness, seek to overthrow the current rulers of their kingdom to rule in their stead, and have connections to dragons)
  • Roy (Young and naive princes from fantasy video game series with powerful swords and pyrokinetic abilities who fight against dark forces to save their kingdom)
  • Yuma Ilvern (JRPG protagonists who have the ability to transform into dragons)
• EVA-01 vs...
  • GaoGaiGar (Deconstruction vs. Reconstruction of the Super Robot genre, and their usual opponents have both barriers and regenerative abilities)
  • Shin Godzilla (Hideaki Anno's most famous creations who crossed paths before, with the former fighting against Lovecraftian horrors while the latter is an eldritch take on a classic monster)
  • Ultraman (Giant humanoid warriors that merge with humans with a "Shin"-esque name and defend humanity against kaiju with the aid of an anti-monster organization (SSSP/NERV). Plus, both characters and their respective series employ heavy usage of Christian symbolism, and Hideki Anno was heavily inspired by Ultraman to boot)
  • Wing Gundam/Wing Gundam Zero (Iconic mecha that appeared in the 90s with a religious theme piloted by very young teens)
• EVA-02 vs. Strelizia (Old vs. new fight of mechs piloted by female teenagers who are designed to fight against otherworldly threats and are associated with the number 2)
• Eve vs. Eveline (Mutated monsters [with the former's mutations being otherworldly while the latter is genetically made] who take the forms of female humans, have similar names, and corrupt other beings into being like them)
• Eve Code: Antithese vs. Herrscher of the Void (Walking Spoiler that are the possesed versions of good and amnesiac characters, desire the destruction of humanity as they persive it as beneath them, bear titles reminesce of that (Queen of Extinction and Herrscher of the Void respectfully), have darker and more aggresive versions of their main counterparts powers, and can creater illusions)
• Everest vs...
  • Cerberus (Ice-breathing dogs)
  • Glaceon (Ice-breathing dogs with human masters)
  • Larimar (Fan-favorite superpowered canines accustomed to the cold that serve as additions to the main cast. Both wear snowflake symbols and have white fur. Everest got ice powers from a meteor while Larimar was born with Jewelpet magic)
  • Liberty (The seventh organic pups of the PAW Patrol, and they have never met in canon)
• Evolto vs...
  • Baby (Aliens who come to Earth with the objective in their hands to conquer the world and fulfill their objective using the main characters as tools of their plan, they'd be the cause of events of great importance that would lead the protagonists to reach limits. Both come from royalty (Baby being a mutant machine of the genes of the king of the Tuffles and Evolto belonging to the royalty of his planet and the bloody tribe) and their species was finished by another (The race of the tuffles with the saiyans and the last group of the blood tribe with the people of Mars), they have the ability to take over bodies (Baby as a parasite created by King Tuffle and Evolto being able to take control with his DNA), which they have used to take over people and develop catastrophes on Earth, they have used it on father figures such as Vegeta and Soichi to remain in disguise and use them as his main guests throughout his saga. They developed a plan that took a long time to work, as well as using their intellect correctly (Baby possessing Vegeta who was the strongest at the time and creating an army involving Goku's loved ones. Evolto manipulating every part of Japan to create conflict and taking possession of every person close to Sento, the protagonist), both have obtained power from those they possessed. They're arrogant in have an arrogant in personality with their rivals as well as having a constant evolution that helps them eliminate their obstacles, however their purposes conflict with each other, with Baby wanting to get his race back and Evolto wanting to destroy alien species. But they both want to create a new world for themselves)
  • Deoxys (Powerful aliens who constantly evolve between forms and attack Earth)
  • FU (Arrogant and sadistic aliens who attack Earth with dreams of conquering it)
  • Lord Boros (Extremely powerful aliens who are leaders of groups, with the former desiring to become a god while the latter obtained god-like power and is merely seeking powerful foes to fight)
• Exdeath vs. Janemba (Powerful, sword-wielding antagonists who were created through spiritual matter flowing incorrectly, desire only destruction, have powerful reality-warping abilities, and have more powerful forms)
• Ezio Auditore vs...
  • The Prince (Royal, charming swashbucklers)
  • Ra's al Ghul (Master assassins and members of organizations who have done as such for centuries)
• Fairy Leviathan vs. Stick Straw (Members of groups of four who wear blue, wield long melee weapons, use the water element, and can summon long dragons)
• Fatalis vs. Seth (Black dragons that serve as powerful bosses in their respective franchises)
• Falco Lombardi vs...
  • Han Solo (cocky space pilots)
  • Revali (Smug humanoid birds with blue feathers, fight with ranged weaponry, and are characters made by Nintendo)
  • Zelkin Fiskekrogen (Blue-feathered bird-like humanoids fighters that come from settings inspired by Star Wars and have very constrasting personalities and fighting styles [Falco is pretty arrogant and cocky, fights with hand-to-hand but he rather fights from a distance with guns; meanwhile Zelkin is pretty stoic and fights with a plasma sword up close])
• Father vs. Singularity (Progenitors of antagonistic homunculi)
• Farah Oersted vs. Alena (Hotheaded tomboys who are always eager for adventures, drag their chilhood friends with them despite their distaste [Rid Hershel and Kiryl], both returned to returned to their old villages only for them to be devoid of life, they fight with the use of martial arts instead of weapons or magic like their team mates)
• Faust vs...
  • Arakune (Respected scientific figures who became strange, insane beings after something went horribly wrong [Faust following the death of one of his patients, Arakune being transformed horrifically after being exposed to seithr] wearing facial coverings who are among the oddest characters in their series from ArcSys fighting games)
  • Doctor Mundo (Towering Mad Doctors with Blue-and-Orange Morality who fight using oversized hospital instruments)
  • Valentine (Mentally-unstable doctors in fighting games who wear masks)
  • Yoshimitsu (Confusion Fu masters from fighting games)
  • Franken Stain (Mad scientist of dubious morality that fight wearing white robes and using a slashing weapon, are unintentionally responsible for several events in their series, are usually persive as insane, and are named after well respected stories of the 40s and 60s)
• Featherine Augustus Aurora vs Lord English (psychotic and sadistic monsters who like to torment the protagonists, and whose power is so great that they can rewrite their own series' plot to fit their own desires)
• Felix vs. Riku (Friendly rivals and Anti-Hero Magic Knights)
• Ferry vs. Hu Tao (Cute Ghost Girls from gacha games with big Animal Motifs [foxes for Ferry, butterflies for Hu Tao] with control of fire powers)
• Fester Addams vs. Grandpa Munster (Wacky Mad Scientist-type characters who are members of rather ghoulish and macabre families)
• Filia vs...
  • Medusa (Marvel) (Heroes with Prehensile Hair who were born to a powerful family)
  • Yukako Yamagishi (Teenagers who awoke one morning to discover that they can now fight using their hair)
• Finn the Human and Jake the Dog vs...
  • (Jake only) Evil the Cat (Villainous cat vs. heroic dog)
  • Hiro and Baymax (A Boy and His X, in this case shapeshifting dog vs. Robot Buddy)
  • Mordecai and Rigby (Best friends and heroic duos from early-2010's Cartoon Network shows)
  • Seryu and Koro (justice-seeking duos made up of a courageous but reckless human warrior and their shapeshifting, dog-like companion, with the former being truly just heroes while the latter are brutal Knight Templars)
  • (Finn only) Sir Sadlygrove Percidal (Book Dumb, sword-wielding teen adventurers)
  • Wander and Sylvia (Both pairs of a heroic biped and their quadrupedal counterpart who travel through a vast setting, helping anyone they can along the way. Both parties have one character who is more laid-back and one who is more aggressive, but both pairs are True Companions.)
• Fiona Mayfield vs. Noelle (Polite maids that fight using BFS)
• Fire Lord Ozai vs...
  • Father (Big Bad evil fathers with control over fire who are fighting against a group of children lead by a bald boy and both were The Unfavorite to their heroic brothers by their own evil fathers)
  • Lord Sombron (Big Bads who are horribly Abusive Fathers that manipulated their good-natured child [Zuko and Veyle respectively] into becoming villainous. They wish to rule a land divided up into four nations and will kill anyone that doesn't follow them, and it is said that they are the one that The Hero is prophesied to defeat)
  • Ra's al Ghul (Leaders of evil, Asian-inspired organizations who use their daughters [Azula for Ozai, Talia for Ra's] as minions who utilize magic)
  • Master Cyclonis (Villainous conquerors who rule lands of evil with goals of conquering all other nations.)
• Flame Princess vs.
  • Cloudy Jane (Ex-girlfriends of The Heroes of early-2010s Cartoon Network shows with elemental powers and fiery tempers, who were heavily wronged by their exes)
  • Lapis Lazuli (Cartoon Network girls who have been imprisoned for many years and developed emotional problems because of it, but then were freed by a happy young hero [Steven and Finn])
• Flik vs. Z-4195 (ant protagonists of animated movies made in 1998)
• Flippy vs. Bluey (Antagonistic, psychotic bears hailing from series which juxtapose cute cartoon animals with violence and gore. They both also fight or have fought in brutal wars and use knives frequently)
• Fluttershy vs. Joule (Butterfly-themed superbeings and singers attached to a fast and blue main character.)
• Flynn Scifo vs. Gawain (Noble knights with extreme loyalty to their kingdoms even when it blocks their judgment, have light-based attacks, hold extreme grief for decisions done in the past, have clashes with purple-haired swordsmen, and usually act as the responsible guy in their respective teams)
• Foo Fighters vs...
  • Power(Both are actually the corpses of young women that are inhabited by supernatural beings. They have liquid manipulating abilities [water and blood respectively], which they can use to form weapons, heal themselves and others, and even limited shape-shifting. They both start as antagonistic towards the protagonists, as well as being incredibly immature and lacking social skills, but throughout the story they mature and become incredibly close to the heroes. Unfortunately, this ends in tragedy, as they both die at the hands of the main villain)
  • Sheldon J. Plankton (plankton-based characters)
• Frank Drebin vs. Lt. Sean "Topper" Harley (Protagonists of spoof action movie franchises)
• Frankenstein's Monster vs. The Wolf Man (classic Universal monsters, and they've met)
• Francis Drake (Fate) vs...
  • Miss Fortune (Red haired female captain pirates that fight against hordes of enemies with dual-guns)
  • Darli Dagger (Guns vs. Sword. Female captain pirates with relaxing, yet fight loving personalities)
• Freddy Fazbear vs...
  • Monokuma (Animatronic monstrosities)
  • (using his abilities from Five Nights at Freddy's World) Teddie (Anthropomorphic bears who fight in digital worlds against god-like entities, with the former being an evil entity who started as a child but became a ghost trapped inside a "shell" following their death while the latter is a hero who started as a ghost but became human after having a human form be grown from within him)
• Freddy Krueger vs...
  • Candyman (Film slashers with Red Right Hands having sharp implements in them who are associated with liminal realities (dreams for Freddy and folk myths for Daniel) and in their backstories were killed by angry mobs)
  • Darkrai (Terrifying monsters who attack people in their dreams)
  • King Worm (Abstract creatures who kill people in their dreams, with Freddy Krueger targeting bad dreams and King Worm targeting good dreams)
  • Mannish Boy (Dream Walkers who kill people in their dreams)
  • Reala (Living nightmares who wear red and hunt children in their dreams to kill them)
  • Pennywise (Classic horror movie villains who thrive off casting nightmarish illusions to their targets [Freddy doing this through nightmares, Pennywise through shapeshifting], thriving off their fear)
• Fred Flintstone vs. George Jetson (Bumbling Dad protagonists from rival Hanna-Barbera cartoons that have opposite premises)
• Frisk vs...
  • Iji (Lone humans forced to fight aliens or monsters, that could get through their challenges without taking a single life but that probably, for the purpose of the match, turned to genocide instead, both of whom with in-universe means of coming back from the dead)
  • Ness (Original vs. inspiration fight of children in RPGs with mighty magical abilities, striped shirts, and who befriend a group of characters to fight god-like entities)
  • The Long Quiet (Knife-wielding heroes of games with various different endings depending on how you interact with the other characters, are able to become nearly unkillable through determination, with one having a heart motif and the other killing their enemies via stabbing them in the heart)
• Frog vs...
  • Meta Knight (Small, unexpectedly powerful swordfighters with capes)
  • Specter Knight (Brave knights who were cursed with monstrous forms by sorcerous villains)
• Frost vs...
  • Killer Frost (Female cyan-haired cryokinetics owned by Warner Bros.)
  • Kula Diamond (Female cryokinetics who gained powerful through the interaction of an evil organization specializing in manipulating the human body to become more powerful [The Cyber Lin Kuei for Frost, NESTS for Kula], with the former embracing her abilities and becoming a cruel, cold-hearted commander of them while the latter betrayed the organization to become a hero while also being kind-hearted and innocent)
  • Kylo Ren (Evil warriors who betrayed their heroic masters and are corrupted with no hope of redemption and seeking a path only consumed with power, hate, anger, and suffering)
• Funny Valentine vs...
  • Senator Steven Armstrong (Fictional, super powered American politicians from over the top Japanese media who are both Affably Evil Anti-Villains who want to improve the United States, albeit in contrasting ways [with Valentine wanting infinite prosperity with no conflict while Armstrong wants conflict that leads to progress and freedom]. Both of them are so charismatic and dedicated to their goals that some fans even admit to agreeing with them)
  • Takaya Sakaki (Gun-toting users of Fighting Spirits who lead Cults of Personality and have villainous ties to Jesus Christ)

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