In Taz-Mania, Digeri Dingo has MANY crowning moments of funny.
"I really thought Taz was my friend. I can't believe he'd stoop to such ugly depths for his own personal gain. That's MY job and he knows it!"
"What if George Washington didn't feel like crossing the Delaware? What if Thomas Edison didn't feel like inventing the lightbulb? And hey, what if the producers of this very show didn't feel like producing it and odds are, they don't!"
"Kids, that's a literary reference, you look it up when you're in college!"
(Digeri impersonates Taz's face) "Why for you hiding in the cold cold bushes with a shovel?"
"Then you can come back and.....like Dingo! Haha, I am capable of saying anything!"
In one episode of Coconut Fred's Fruit Salad Island, Fred and the gang adopt a "Rainbow-Butted Fruit Monkey" (a baboon with a mood-ring for a butt), which they name Happy. The humor comes when they introduce him to Mr. Greenrind:
Slide and Slide: His name is... ta-dah! (show the pink paint on their rear ends)
Mr. Greenrind: Who would name an animal "Pink Banana Butts"?! That's weird, even for you two!
Or the one where Secret dresses in drag to try and calm down a giant panda (he wasn't allowed to physically hurt him because pandas were endangered), complete with fishnets. He walks offscreen, looking very upset, and there's the sounds of a beating. Morocco keeps offering "helpful advice" like "Maybe he needs a hug. Maybe there's a thorn in his paw..." Finally, Secret is thrown back onscreen, and winds up half-buried in a building.
"Or maybe he's just a jerk..."
The hilarious scene in Cartoon Planet where Zorak tells a story about George Washington telling his father that it was his twin brother who chopped down the cherry tree and not him. Space Ghost and Brak call him out and Hilarity Ensues between them, eventually forcing Zorak to admit that George told the truth.
Rumor Weed: I'm a talking weed, you're a talking carrot. Your point was...?
I can think of lots of funny Peanuts moments- Peppermint Patty finding out that she graduated from a dog school in A Charlie Brown Celebration, Snoopy deflating the wheel on the umpire's chair and getting thrown out of Wimbledon in Bon Voyage Charlie Brown, Marcie getting her foot caught in a ball washer at a golf course because she thought it was a "shoe washer" in It's an Adventure Charlie Brown, Peppermint Patty thinking that a butterfly that landed on her nose turned into an angel and flew away and calling a call-in radio show to talk about it and having the host say "Sorry folks, just another nut calling in" (also from It's an Adventure Charlie Brown), Linus designing a video game and having the villain resemble Lucy and Lucy's reaction when she sees it from an episode of The Charlie Brown and Snoopy Show, Lucy watching Linus draw a picture of her for a school project and wanting him to "put in the mouth" but Linus is reluctant because he is planning to draw her a huge mouth and Lucy's reaction when she sees it from another episode, Snoopy and a bear both scaring each other in Race for Your Life Charlie Brown, and Charlie Brown getting into a motorcycle accident and accidently getting sent to a vets office in You're a Good Sport Charlie Brown.
Frisky Dingo contained many of these from Killface to Awesome X and the X-tacles to Simon to Valerie, but particularly in the first episode when Villain Protagonist Killface uses the severed torso of a twin he shot in a previous scene as a hand puppet as the other twin looks on and this quote:
Valerie: Please don't kill us! Killface: Please don't make it so appealing!
Second season episode where Xander's doctor gets confused by name of the (sorta) evil cyborg villainness:
Doctor: Well, that cracked your C3 and C4 vertebrae, so... you ever see Hooper?
Xander: Yeah, that robot with the big tits!
Doctor: No, but that sounds awesome.
Xander: It is!
Doctor: I meant the Burt Reynolds movie where he's a hard-living stuntman.
Xander: That sounds awesome.
Doctor: It is. Anyway, one more impact to the neck, and you'll be paralyzed.
In "Superbar", the Warden drunkenly talking to Alice's date's suicidally dismembered head.
The Warden: So, uh, dude, how's yer DATE going, huh? I. Was supposed to be Alice's date, YES! And she was gonna fall in love with! RrrrrrME! And now it's YOU! Who's got yer dirty little hands all over MY sweet Alice, instead of. MmmmmME!
Jared: Sir, maybe you've had enough...
The Warden: MXPLH- HEY! Mind yer own business, bartender, and just keep the (bleep)damn drinks coming!
The Warden's (he seems to get these a lot, doesn't he?) completely deadpan observations on the inmates' dreams.
The Warden: Ah, yes, a falling dream. Caused by feelings of helplessness and insecurity, much like an inmate in a prison. How obvious.
Time Police: (sung in a Motown style) Hey! Wait! You can not escape! Never run away from the Time Police! You will not survive!
Drawn Together: Xandir's suicide in "Gay Bash". ("This could take a while.")
Also, Foxxy's masturbation lesson with Wooldoor.
The roleplaying episode. Especially when they start roleplaying within the roleplay.
Live Action Cow's dramatic battle with Live Action Squirrel. The housemates' excited reactions to what are clearly a couple of photographs being moved around (and not even being moved around; the camera is simply cutting back and forth between two still shots) are just the icing on the cake.
The President trying to communicate with the alien probe by playing the tune from Close Encounters of the Third Kind. And when that doesn't work, he tries "Axel F". The baffled faces of the nearby soldiers, in contrast to the stoic Secret Service agents, make it even funnier.
And when that doesn't work: "Commander, do something violent!", followed up by "Eat lead, alien robut! ...Evidently, they eat lead. Huh."
As General Monger briefs the President's staff on his collection of monsters, he eventually has to shoo out a woman who keeps screaming in horror. When Monger gets to Susan (AKA "Ginormica"), a scream identical to the ones before it is heard, and turns out to be coming from The President.
Plus the guy in The War Room getting shot by a tranquilizer dart the second he mentions Area Fifty-urrrgh!
The scene on the the spaceship where B.O.B., upon receiving a gun and pretending to be part of the invading army, accidentally activates the gun and kills a goon- it's not so much what B.O.B. does but the expression on his face when it happens- you can almost hear him thinking oh look a dead goon, COOOOOOOOOL...
Space case blob monster B.O.B. hitting on a gelatin mold.
Dr. Cockroach cracking the supercomputer on Galaxxhar's ship through Dance Dance Revolution: "One thing you don't know about me, my dear... my Ph. D. is in dance!"
There's one near the very beginning that cracks me up because of the Missing Link's deadpan tone:
Abe Lincoln: "Y'know what hurts the most, Joan? This nail I just stepped on. But there's a metaphorical nail in my OTHER foot that hurts the second most, and that's from you stabbing me in the back. So, maybe I should have gone with a stabbing metaphor instead of a nail metaphor, but it's TOO LATE FOR THAT NOW ISN'T IT?!"
Doctor Manson: "And when you eat your sweets,/make sure you try/to limit your servings/or you'll DIIIIIIIIIIIIIIIIIIEEEEEEE!! Everybody!"
For some demented reason, I laugh out loud when watching the Thunderbirds episode "Alias Mr. Hackenbacker"; they had this fashion show in a futuristic jetplane, with beautiful music accompanying the models. However, just as the music reaches a beauty point, we cut back to the jet roaring in the air, no music. Hilarity. This was done for almost every model, except for the last one, where the music was allowed to end properly before a nice dissolve to that crazed plane.
In the Mega Man cartoon, Mega Man steals Pharaoh Man's power. Rather than be cowed or blasted, he punches Mega in the face when he spouts his Catch Phrase.
From Squidbillies. Early is upset that he didn't win Jack Squat in the lottery, then decides to make some money by putting it on a hat:
Made even funnier by Todd Hanson/Dan Halen's completely deadpan delivery.
Italian animator Bruno Bozzetto (of Allegro Non Troppo fame) tackles the tricky question of "where do babies come from?" in his ten-minute short, A Baby Story. It's 10 Crowning Moments of Funny, but the biggest laugh comes when the baby punches the gynecologist in the eye. (The condom gag is a close second.)
To be fair, this scene from Street Fighter was probably meant to be at least somewhat funny, but... well, Guile's take on disarming a bomb... oh, let's just get on with it.
Guile: (muttering to himself) That goes to the detonator... no, this one... no, that's the failsafe... oh, who built this thing?! That's it! SONIC BOOM!
Kyle: So whom shall I choose to be my best friend? Hm?
(camera pans down to Fanboy and Chum Chum latched on his waist with bleary eyes, snotty noses and sickly glows)
Kyle: ... Are these the only choices?
Fanboy: Kyle, before you choose, consider... this. *pulls lever, opening a trap door and sending Chum Chum plummeting down into darkness*
Kyle: *looks down trap door awkwardly* Well. That does simplify things.
In "The Hard Sale" when Oz has succeeded in getting the minimum $1 that he needs to prevent his mom from converting his store into a yogurt shop, he accidentally points to her when he's celebrating. His arm promptly falls off, then explodes.
In the Wacky Races Forever pilot, Dick Dastardly disobeys orders to try and cheat because he thinks his boss is giving him coded messages to do the opposite of what he's telling him. So Dick Dastardly turns his car around to drive a massive cheese wedge between two siblings. Muttley facepalms because Dick Dastardly is less than three feet away from the finish line, but Dick Dastardly declares they can't win fairly, ergo they have to cheat!"
The first Bratz animated movie, Starrin' and Stylin' is So Bad, It's Good, and has many really good moments. This channel has all the parts. Highlights include Sasha's dancing and Jade's lapse in fashion sense.
From an episode of Squirrel Boy when Rodney loses Andy's toy rocket in a tree and Mr. Johnson finds out. He says "That's not as bad as I thought" and he takes out a notepad describing what he thought: a drawing of Rodney tying Andy to the rocket and launching it.
In the Lalaloopsy episode "The Big Sheep Sleep", Pillow Featherbed can't sleep, so she goes to Little Bah Peep to borrow her sheep to lull herself to sleep with. When taking the sheep home they reach a fork in the road and Pillow goes down the left path while the sheep go down the right, then shortly after they both go offscreen Pillow notices the sheep are gone and darts after them.
Later, the youngest and fastest sheep runs into frosting and gets covered in it, and while chasing it Pillow comments "Stop that cupcake—I mean, stop that sheep!"
At the end of the episode, the aforementioned young sheep keeps jumping on Pillow while she's trying to sleep and keeping her up all night.