- From "Peek-a-Boo Camera":
Fred: If our wives see that film, we're dead!
Barney: Worse, Betty will kill me!
- The second credits sequence (which is considered more popular than the first one due to Memetic Mutation). At the end, Fred would put out the cat, which would jump back in through the window and toss Fred out. Fred is forced to bang on the door and shout for "WIIILLLMAAAA!!"
- The "Happy Anniversary" scene near the end of the episode "The Hot Piano", where Barney and a group of policemen (It Makes Sense in Context) constantly interrupt Fred with their singing as he tries to give Wilma best wishes on their wedding anniversary, much to Fred's increasing frustration.
- An episode had Fred and Barney assisting what turned out to be a female spy. She asks if they're married, and Barney replies "Nope... we're just good friends."
- Fred is presented with his godchildren, who he says are all named "Fred." Wilma asks if that would get confusing. Fred says, "Not really, seeing as they're all girls."
- In an episode where Stony Curtis comes to the house, Wilma has Betty pretend to be her "upstairs maid".
Fred: We don't have an upstairs maid! WE DON'T EVEN HAVE AN UPSTAIRS!
- In "Son of Rockzilla", Fred (stuck in the namesake monster costume) is been chased by Doris the Finkasaurus (resembling the movie monster) that escaped from the zoo, and then the police. The three run over Barney, who came back with pliers to get Fred's costume off.
Barney: Just for that: I won't help you take off your phony head!
- "The Long, Long Weekend": A female hotel guest is terrified by the sight of Fred and Barney crashing into her room, and calls the manager. The hotel manager picks up the phone.
Manager: Front desk.
Woman: AAAAAAH!!! (unintelligible sobbing)
Manager: ...Would you repeat that, madam?
Manager: No! Not that part!
Woman: Oh. (unintelligible sobbing)
- Fred feigning an ailment in "The Flintstone Flyer" as the two couples are about to go to an opera. Both the English and Spanish dubs of said scene.
- "Wilma Flintsone, a natural redhead?"
- Fred going on a rampage in Mom's Diner when he sees Wilma on TV doing her cooking show, while he's stuck chewing on a steak sandwich that resembles the bottom of a shoe. Also, the one-sided conversation Barney has with Fred when he calls from jail that makes it sound like he hit his mother and smashed her television.
- Fred going on a diet as part of a game show challenge, where he has to drop 40 pounds, and his increasing desperation for food, including attempting to steal a bone from Dino.
- The feud between Fred and Barney when Barney confiscates Freds bowling trophy due to his refusal to pay his membership fee for the gentlemens club they're part of. It quickly devolves into a turf war, with Barney sneaking into Freds yard to take back the various things Fred has borrowed over the years, and then running like hell back to his own yard when Fred catches him.
- This line in The New Fred and Barney Show episode, "Haunted Inheritance".
Fred: (excited) LIABILITIES!