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Gwog: "Geez... what a bunch of freaks."
Dr. Thaddeus John Euphemism: "Says the alien with one eye."
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To put it quite simply, a character or creature that only has one eye.

Monocular vision is symbolic of metaphorical narrow vision and lack of depth perception. As such, many human villains have one eye as an indication of their simplistic worldview. This also provides an excuse for an Eyepatch of Power. Characters who lack perspective on a temporary basis might sport Peek-a-Bangs or some other ocular obtrusion.

It should be noted that "cyclops" more accurately translates to "circle-eye" or "wheel-eye", referring to the eye's size. Therefore, "cyclopean" technically means huge, and not one-eyed (not to mention that the Cyclopes themselves were giants).

Not to be confused with the Faceless Eye, cyclopes have a recognizable facial structure, with at least a mouth or One-Eyed Shot which is just a camera shot of a person's eye.

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For other deviations from normal eye structure, see Eyeless Face, Third Eye, Oculothorax, and Extra Eyes. Compare to the robotic version, the Cyber Cyclops, and Eyepatch of Power. For the mythological being, specifically, see Classical Cyclops.

Oh, wait, were you looking for that guy with the visor?


Examples:

    open/close all folders 

    Anime and Manga 
  • 3×3 Eyes: Yabaru, one of Kaiyanwang's followers, is a massive squid-like demon with a single massive eye composing most of his face. Worth noting that he's the one who relies the most on brute force.
  • Bakugan has Billy's guardian bakugan Cycloid, a giant one-eyed creature modeled after the ones from the Greek Mythology. His signature weapon is his hammer.
  • Mummymon of Digimon Adventure 02 has only one eye on the left side of his face.
  • Monster Musume: Manako, the Friendly Sniper. She's a Cute Clumsy Girl due to having trouble judging distance to objects that are really close and horribly self-conscious because of all the attention her eye gets. The anime clarifies that she is actually a race called a monoeye, while true cyclopes are a type of one-eyed giant, but the official English translation of the manga continues to call her a cyclopse.
  • Natsume's Book of Friends has the one-eyed youkai Chukyuu, and several other minor youkai as well.
  • Nura: Rise of the Yokai Clan: Hitotsume Nyūdō is a cyclops and the chairman of the One-Eyed Demon Clan.
  • Nurse Hitomi's Monster Infirmary: The title character is a school doctor with a single large red eye. Her name even means "pupil".
  • Toriko: Starjun's Intimidation and Gourmet Devil is a massive blue Cyclops with horns. One-Eyed monsters appears among the inhabitants of the Hex Food World, among them Dinner the Blue Oni.
  • In The Voynich Hotel, one of the three devils that are minor antagonists is a cyclops who keeps her eye hidden under a plate-like mask. She freaks out the one time she's seen with her eye uncovered... which is when she had just gotten out of the shower, so she covers her eye instead of her body.
  • Yaiba: Gold and Silver. In the latter case, it's also his weak point. (Gold's eye is just as bouncy as everything else.)
  • The anime of Yo-Kai Watch has Insomni, a small, Cute Monster Girl youkai with only one eye. There's actually a large number of one-eyed yokai, including the ones mentioned under Japanese Mythology below.

    Card Games 
  • Magic: The Gathering: There are quite a few cyclopes in the setting's various worlds.
    • Dominaria, the closest the game has to a "main" setting, hosts cyclopes in the Ekundu Mountains. They're noted to have a very simple language — their tongue has only fifty words, ten of which mean "kill".
    • Ravnica's cyclopes are horned, towering brutes often employed by Red-aligned guilds. Most live among the Gruul Clans, but they also serve as fortress guards in the Boros Legion and in the Izzet League as heavy lifters.
    • In Theros, a plane heavily based off of Classical Mythology, cyclopes are animalistic, aggressive brutes who live in the wilderness and attack anyone they come across. They don't feel pain, and are capable of razing villages on their own. Some even wield lightning.
  • Yu-Gi-Oh! has a few, such as the Hitotsu-Me Giant (simply "Cyclops" in the Japanese version) and the Opticlops.
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    Comic Books 
  • Alan Ford: During Number One's retelling of the Odyssey, we find out that the dreaded Cyclops living in Sicily were actually a tribe of shy one-eyed midgets who were using their reputation as fearsome man-eating giants to keep strangers at bay. They bribe Odysseus and Number One to make them keep the secret and leave their lands forever.
  • Copperhead: The Sewell family are from a species with only one large, centered eye among other alien qualities.
  • Dark Horse Monsters: A huge reptilian beast with one eye shows up in one of the stories.
  • The eighth issue of the Ewoks comic had the witch Morag attempt to kill the Ewoks by resurrecting a one-eyed beast known as the Kreegon.
  • Kull the Destroyer: The comic has Gasshga, a giant blue cyclops.
  • Marvel Comics:
    • Psyklop, a The Avengers and Incredible Hulk supervillain, has one giant red compound eye. He can use it to fire energy beams and to hypnotize people.
    • New X-Men: Basilisk, in his second incarnation, is a mutant with an abnormally large physique, no hair, and a single eye in the middle of his forehead from which he can shoot paralyzing Eye Beams.
  • Saga: D. Oswald Heist is a cyclops who writes romance novels.
  • Supergirl: In Demon Spawn, Supergirl fights off Nightflame and her demonic minions. One of them is a short, wrinkled, bald, purple-skinned cyclops dressed in red robes. He attempts to suck out Supergirl's powers and life essence and transfer them to Nightflame.
  • Viz: Farmer Palmer is very proud of his cyclops grandson, the result of generations of first-class inbreeding.
  • Wonder Woman:
    • Diana and Wonder Girl once had to deal with Cyclon, the giant, one-eyed progeny of Polyphemus and Medusa. Fortunately, he turned out to be friendly.
    • In Wonder Woman (1987), Diana and Hippolyta have to deal with Polyphemus, who was imprisoned in the underworld behind Dooms Doorway and has spent centuries starving in a cave still blinded from his encounter with Odysseus. He is further agitated because he ate the god Pan and god flesh doesn't take being eaten very well.
    • Slaughter, one of the Children of Cronus, is a big, blue, twelve-armed cyclops centaur with a single, red eye.

    Comic Strips 
  • Garfield: The January 16, 1981 strip has Garfield encounter a one-eyed dog.

    Fairy Tales 
  • "One-Eye, Two-Eyes, and Three-Eyes": One-Eye has one eye in the middle of her forehead.

    Films — Animated 

    Films — Live Action 
  • The Cyclops: The title creature. Kinda. He's really a giant with half of his face melting over his right eye. It's very similar to the director's other film War of the Colossal Beast (even the monster is played by the same guy).
  • Dark Light: The monsters living in the catacombs under the Knox household have one big eye making up most of the upper half of their heads.
  • In Dasepo Sonyo, there is a Butt-Monkey named Cyclops, who only has one eye in the center of his forehead.
  • The Golden Voyage of Sinbad had a one-eyed centaur.
  • Monster Brawl: One of the combatants is a cyclops who works as a blacksmith in his spare time and enters the ring with a hammer. He can also shoot Eye Beams out of his eye.
  • Puppet Master: One of the puppets in Pupper Master 7: Retro Puppet Master is a cyclops.
  • The Three Stooges: There's a two-headed, hairy cyclops in The Three Stooges Meet Hercules.
  • Wrath of the Titans: They make an appearance, defending the land where Hephaestus lives. They attack the heroes, but relent in time and guide them to the Smith God.

    Literature 
  • Bailey School Kids: Cyclops Doesn't Roller-Skate has Dr. Polly, who may or may not be a cyclops.
  • The Crimson Shadow: The cyclopean race. Due to having only one eye, their depth perception is very bad, so they are generally poor at using ranged weapons. One that we see though makes up for this by having a crossbow equipped with small mirrors on each side to help him aim.
  • Disgusting McGrossface: A one-eyed creature can be seen on a police sketch.
  • The Divide: There's a female cyclops by the name of Turpsik in the second book, who writes extremely depressing poetry.
  • Fighting Fantasy has used cyclopes as enemies plenty of times. The most notable one is the Final Boss of Seas of Blood, which you have to fight bare-handed and choose all your attacks.
  • The Girl, the Dog, and the Writer in Provence: Discussed when it's mentioned that even someone who was nearsighted and had one eye and dirty glasses could see that Vivi and Tobias were in love.
  • The Lost Years of Merlin: Balor from The Seven Songs of Merlin, the second story in the series. It's made worse by the fact that his gaze can kill you.
  • The Odyssey: The most well-known cyclopes today, Polyphemus, was the son of Poseidon and a sea nymph, a shepherd and a man-eater. Depending on the Artist he's either shown with a single eye where a person's eyes would be or — worse — his eye sockets are covered skin and a single eye rests in his forehead.
  • Percy Jackson:
    • Polyphemus appears as an antagonist in The Sea of Monsters. Both he and Tyson, along with almost every other cyclops in the series, are Percy's half siblings, to his surprise.
    • The only ones not born to Poseidon are the trinity of cyclopes that are his elder half brothers. They are the ones that forged the iconic weapons the Big Three (Zeus, Poseidon and Hades) used in their war against their father.

    Live-Action TV 
  • Night Gallery: In the vignette "Prof. Peabody's Last Lecture", the skeptical Peabody is transformed into a one-eyed monstrosity with a face like a pile of seaweed after injudiciously poo-pooing the Great Old Ones and then reading aloud from the Necronomicon.

    Magazine 

    Music 
  • Daniel Amos: In the short story that accompanies the ¡Alarma! album, the narrator gets threatened by a one-eyed giant.

    Mythology 
  • In Australian Aboriginal mythology, the Papinijuwari are a race of one-eyed giants who live in the sky and come down to Earth in the form of shooting stars in search of sick and dying humans to consume and drain of their blood.
  • Celtic Mythology: The Fomorians have many descriptions, but one of them is as weird creatures with one eye, one arm, and one leg. Balor was their leader and combined this with Deadly Gaze and Eye Beams.
  • Classical Mythology:
    • The Trope Namers are the original three cyclopes of Greek myth: Arges, Steropes, and Brontes. They were master craftsman and giants of considerable size and power (and prone to fits of rage); the Greeks coined the term "cyclopean" to refer to ancient, precursor structures that they presumed could only have been built by mighty giants. Their father Uranus was so afraid of their power and fits of rage that he imprisoned them in Tartarus. When their nephew Zeus finally freed them to help in overthrowing their brother Cronus, they worked together to forge Zeus's lightning bolt (each contributing one third of the weapon's elements; the blinding light, lethal heat, and deafening thunderclap, respectively). They also created Poseidon's trident and Hades's helmet of invisibility. Eventually, the brothers were surpassed by Zeus's son, Hephaestus, to whom they and their descendants became assistants. They also created the Solar and Lunar bows and arrows of Apollo and Artemis.
    • The arimaspi, a race of one-eyed humans and the archenemies of griffins.
  • Japanese Mythology is full of one-eyed creatures, including the Hitotsume Nyuudo (one-eyed monk), the Aobozu (Blue Monk), the karakasa (an umbrella come to life), and the Ippondatara (a giant with one eye and one leg).
  • Odin from Norse Mythology is depicted as having one eye after sacrificing the other to the Well of Mímir in exchange for the ability to tell the future.
  • Sinbad the Sailor has met a Cyclops in the Polyphemus mold before.
  • Slavic Mythology has the terrifying Likho, an embodiment of evil, fate, and misfortune.
  • Bungisngis is a one-eyed giant in Philippine folklore who is described as having huge tusks and superb hearing. He's said to be pretty dimwitted, but also very jovial and fond of laughing.

    Pinball 

    Tabletop Games 
  • Call of Cthulhu: The supplement Pursuit to Kadath's adventure "The All Seeing Eye of the Alskali" has the titular Alskali monsters, whose single eye can hypnotize their victims.
  • Changeling: The Lost: One of the Ogre kiths is the Cyclopean. They almost always have a missing eye and their mien makes it look like one central eye. They do come in other varieties though.
  • Dungeons & Dragons has had a long history with Cyclopes.
    • The Greek Mythology version first appears in the 1st Edition Deities and Demigods Cyclopedia. There are two variants, the Chaotic Good Greater Cyclops (based on the ones who serve Hephaestus in his forge) and the Lawful Evil Lesser Cyclops (based on Polyphemus and his ilk).
    • Cyclopes have also appeared as the core Monster Manual in some editions, but in those cases there are just one species of Cyclops, which has more in common with the Lesser Cyclops, being violent but dimwitted recluses that spend their days tending to sheep and smashing trespassers with their clubs.
    • Like many things in 4th Edition, Cyclopes were drastically changed. Instead, they originate from the Feywild's version of the Underdark, where they work as a Servant Race for the Fomorians, a hideously deformed race of insane, subterranean giants who constantly war with The Fair Folk on the surface. While this change was one of the more welcomed ones due to the depth it gave them, it was quietly dropped with the advent of 5th edition and cyclopes went back to their usual characterization.
    • There are also the Cyclopskin (who are blue Cyclopes) in the 1E Monster Manual 2, and Zargon, the "god" of the Lost City (B-4).
    • The orc god Gruumsh alternates between being portrayed as a cyclops-orc or simply having just one working eye (the other supposedly shot out by the elf god Corellon Larethian).
    • Nothics are hunched, gaunt, insane monsters with faces dominated by a single, immense, staring eye, and can rot flesh from bone with their gaze.
  • Earthdawn: The supplement Scourge Unending has cyclopean ghouls.
  • Pathfinder: Cyclopes are the degenerate descendants of an ancient civilization that once ruled much of the continent of Garund. There are also great cyclopes, which are even bigger and resemble the Ray Harryhausen Cyclops, and kabandhas, cyclopes with no heads and their eye and mouth on their chests (based on a character from the Indian epic The Ramayana).
  • Shadowrun: Cyclopes are a metavariant/subspecies of the troll player race, native to the Mediterranean. They're notable for largely avoiding the Fantastic Racism that baseline trolls face and having been mostly accepted into Mediterranean society, finding steady work at dockyards as labor and security.
  • Warhammer: Most one-eyed creatures have the ability to perceive the Winds of Magic.
    • The Fimir are one-eyed, skull-faced amphibious creatures whose superior perception of the Winds of Magic allows them to roll six dice to channel instead of one, although they're too greedy to share the power dice produced by this channelling.
    • The Beastmen creature known as a Cygor — essentially a hybrid of a cyclops, a minotaur, and a giant — has a degree of magical perception that it uses to find, kill, and usually eat enemy spellcasters.
  • Warhammer 40,000:
    • The Primarch of the Thousand Sons was Magnus the Red, whose defining features were coppery red skin, being a giant, and having just one eye. It wasn't clear for a time whether he was a cyclops, had only one orbit, or simply lacked one eye, although artwork for the Horus Heresy novels and his official Forge World model for the game have him with a normal face and missing his right eye. His Daemon Primarch model has three possible face options, two normal faces missing the right eye and one which is a typical cyclops.
    • Plaguebearers of Nurgle usually only have one eye.

    Toys 
  • Teddy Scares features a cyclops bear named Abnormal Cyrus.

    Video Games 
  • Age of Mythology:
    • Cyclopes appear as Myth Units if you progress to Classical Age with Ares.
    • Another cyclops, Gargarensis, is the main antagonist.
  • In Animal Jam, the Phantoms (evil blob creatures) have one eye in the middle of their bodies.
  • In Assassin's Creed Origins, Brontes (from Greek mythology, above) appears as a boss fight at the end of a side-quest line. Arges and Steropes were later added as Bonus Boss enemies for high-level characters via patch.
  • Basketball Nightmare: You can play against a team of cyclopes.
  • Battle Monsters has Drethdock, a cyclopean monster who comes from the "Monocle" tribe.
  • Castle Crashers: You must defeat a cyclops to rescue the Green Princess. He's revived by the Necromancer as part of the final Boss Rush.
  • Castlevania: There are several cyclopean creatures in the series, two of which serve as bosses in Castlevania III and Castlevania: Harmony of Dissonance. They seem similar to the one from the Golden Voyage of Sinbad, except that they're blue skinned instead of red and carry enormous hammers.
  • Cuphead: A grey-skinned cyclops with a single centrally-positioned horn appears in Rugged Ridge as an Advancing Boss of Doom, starting to chase the player halfway through and destroying any platform in its way.
  • Dark Souls:
    • Kalameet, the one-eyed black dragon from the Artorias of the Abyss DLC for the first game.
    • More traditional cyclopes are relatively tough enemies in Dark Souls II, hippo-like Ogres you can encounter within the first minute of gameplay. Late-game dungeons heavily imply that they are an artificial creation of Aldia.
  • In Day Dreamin' Davey, there is a cyclops that Davey has to destroy by attacking his eye in one Greek mythology stage. Of course, that "cyclops" in his imagined state turns out to be a girl whom he just hit in the eye in class. Oh, Crap! ensues.
  • Don't Starve has the Deerclops, a giant, one-eyed humanoid deer.
  • Doom: Massmouth, from the Game Mod series The Adventures of Massmouth, is an alien with a single eye on an eyestalk. (He was originally a Quake II skin.) He also appears as a bot in Skulltag, a source port focused on multiplayer, where one of his lines is a complaint about his lack of peripheral vision.
  • Dragon's Crown: Big, blue cyclopes appear as boss monsters, and you fight them two at a time.
  • Dragon's Dogma:
    • Giant, tusked cyclopes can be found as enemies.
    • Dragon's Dogma: Dark Arisen introduces the "Gorecyclops", which are darker, evil versions of the normal cyclops.
    • On top of that, the "Condemned Gorecyclops" is also introduced in Dark Arisen. This one is a gigantic enemy boss chained to a wall. It's one of the largest enemies in the game, and far larger than any other Cyclops.
  • Dragon Quest II: Atlas is an amber-skinned, one-eyed, horned giant.
  • Dragonvale: It's possible to breed a Cyclops Dragon.
  • Duke Nukem:
    • The Cycloid Emperor boss from Duke Nukem 3D. Duke even makes a field goal with its eye.
    • Zero from Duke Nukem: Zero Hour.
  • Majesty features a single cyclops named Dirgo, who sports a single enormous eyepatch. According to his Backstory, he was blinded by an unnamed sailor, and is roaming the land seeking revenge.
  • Might and Magic: Cyclopes have appeared in almost every game, either as enemies or as units.
  • Moshi Monsters:
    • Fishlips the Glump has one rather large eye.
    • Lefty, Captain Buck's assistant, has one eye. He jokes about this fact by saying "eye eye, captain!".
    • Zommers are a species that are born with one detachable eye. Later on, they grow an empty eye socket that never has an eye in it.
  • Muramasa: The Demon Blade: The Blue Monk is a large cyclops with a big head.
  • Neopets has the Meowclopses, one-eyed cats.
  • Nioh:
    • Hitotsume-Nyuudo are massive enemies which can be stunned if you land a hit on their eye. Smaller variants also exist.
    • Trailers from Nioh 2 show the Ippondatara, depicted as a fanged, one-eyed and one-legged monster brandishing either a smith's mallet or a giant sword.
  • Orcs Must Die! Unchained: Stinkeye is a cyclops hero class who uses arcane magic.
  • In Pathfinder: Kingmaker, we have Vordakai, the Arc Villain of The Varnhold Vanishing. He was the last king of a race of Abusive Precursors, and is planning to retake his position in the present day.
  • Pilgrim (RPG Maker): Nekaneminorpe is a Cute Monster Girl version of one with Girlish Pigtails.
  • Pokémon: Several Pokémon have only one eye, but the most cyclops-like ones are Dusclops and Trevenant.
  • The Rampage series has Kyle, Myukus, and Eyegore as playable monster Cyclopes.
  • Ratchet & Clank: Up Your Arsenal has two examples.
    • The lowest-ranked Tyrrhanoids have only one eye. A few times in the game, Ratchet will use a Tyrrhaguise to turn himself into one to get through locations guarded by them.
    • The monkeys found in the Florana Jungles also have just one eye. One of them, Skrunch, is adopted by Captain Qwark and becomes a partner for Clank during his three segments in the game.
  • Rayman 2: The Great Escape: Jano has one eye.
  • Remi Lore Lost Girl In The Lands Of Lore has Lore, a living, floating book with only one big blue eye.
  • Resident Evil: Revelations: The Final Boss, Norman's One-Winged Angel, is a Tyrant-like monster riddled with Body Horror; notably, his whole face split in half, revealing a red tumorous mass with a single eye beneath. It's not merely cosmetic, as it allows him to blind the players with sudden flashes of light to perform Flash Step and illusionary clones.
  • Rift: Cyclopes seem to be denizens of the Plane of Earth. They're built along the same large and solid lines as bahmi (although they tend to be even taller), but have ivory-yellow skin, vaguely bestial features, and the definitive single, centrally-positioned eye.
  • The Skylanders series has a number of them.
  • Space Fury: A cyclopean alien head comes onto the screen to antagonize you throughout the game. A Distaff Counterpart appears in the homebrew sequel game Ms. Space Fury.
  • Space Harrier has one-eyed woolly mammoths.
  • Spelunky: One of the unlockable spelunkers is a "goofy cyclops".
  • Super Mario Land 2: 6 Golden Coins: The Kyororo are cyclops monsters in the Pumpkin Zone.
  • Metroid:
    • Metroid II: Return of Samus: Senjoo, Seerook, Mumbo, Halzyn, Gravitt, Yumee, and Ramulken all have one eye, although they are also much smaller than the mythological cyclops. Autoad and Autom are Cyber Cyclops, while Pincher Fly takes it to Oculothorax.
    • Super Metroid: Mother Brain's alternate form is an one-eyed giant.
    • It's seen again in a flashback in 3D at the beginning of Metroid: Other M.
  • Teenage Mutant Ninja Turtles: Tournament Fighters: In the Genesis version, the "Magma Ocean Planet" stage has a gigantic cyclops lava monster in the background.
  • In Titan Quest, Polyphemus the cyclops from the Odyssey appears as a boss. You also meet some other cyclopes while ascending Mount Olympus. One last one is shown turned to stone prior to the fight with the Gorgon Sisters. Finally, a duo of cyclopes named Brontes and Steropes are bosses in a sidequest of Act IV in Hades. All of them are massive reddish humanoids armed with stone clubs and capable of attacking with stone-shattering shockwaves and stunning howls. They were classified as Magical beasts before Ragnarök, which classified them as "Giants".
  • A Total War Saga: TROY: Polyphemus is a pirate who uses a dwarf elephant's skull as a helm and wields a mace tipped with a ram's skull, implied to be the distant source of myths about a monstrous, cyclopean son of the sea god who lived on a distant island and reared sheep.
  • Trog: The one-eyed cavemen called the Trogs.
  • Warcraft: Ogre magi have two heads, one with two eyes and another with one. Cyclopean ogres of the single-headed variety also exist in the Warcraft Expanded Universe. The latter category rarely appear in World of Warcraft (although ogre magi are common enough), but WoW did introduce their kin the Gronn, who bear a resemblance to the cyclopes from The 7th Voyage of Sinbad.
  • Will Rock: A cyclops appears as the first boss, capable of hitting you from far away by spitting stones at you. It becomes a Degraded Boss soon enough.
  • Wizard 101 has an area called Cyclops Lane, which has quite a few of the creatures.
  • Wrath Unleashed: A monstrous cyclops with a spiked turtle-shell (that may just be a form of crude armor) is part of the Dark Chaos roster.
  • In the Xena: Warrior Princess game for the PlayStation, a cyclops guards King Valarian's island stronghold in the Isle of Kronos stage. In a Shout-Out to The 7th Voyage of Sinbad, he has one horn on his forehead, and if the player uses the "chakram-cam" feature, it can be seen that he has satyr-like legs similar to Harryhausen's cyclopes.

    Visual Novels 
  • Love at First Sight is about a romance between the two-eyed protagonist and Sachi Usui, an injury-ridden cyclops girl.

    Webcomics 
  • Schlock Mercenary: The appropriately named Uniocs have one basketball-sized eye on top of a stalk on their shoulders above the mouth; their brains are apparently down in the pelvic area. Depth perception isn't a problem because their one big eye can rapidly shift focus, and they can see on the microscopic scale as well. There's also a comic where it's mentioned that there was a Unioc dressed as a cyclops at a physics convention.

    Web Original 

    Western Animation 
  • Adventure Time: Cyclopes aren't uncommon. One plays a major role in the episode "Another Way".
  • Aladdin: The Series: Fasir is eventually revealed to be one. Also, there's his brother Fashoom.
  • The Angry Beavers: In "Friends, Romans, Beavers!", after accidently time traveling to Ancient Rome and being forced to fight in the Colleseum, the beaver brothers face off against a giant cyclops. Norbert points out that the cyclops has two eyes instead of one, which drives the senstive monster into a crying fit as the other cyclops' made fun of him for it.
    Cyclops: You don't know what it's like being born with two eyes.
    Norbert: Well, actually, I kinda do.
  • Arthur "D.W. Tale Spins" has Buster (a rabbit) as a cyclops who also only has one ear.
  • Beany and Cecil: In "The Wildman of Wildsville", the Wildman paints two TV tuning knobs on Cecil's nostrils. When he turns one of them, Cecil's eyes conjoin to form the CBS eye, making him a default cyclops at least for the gag.
  • Ben 10:
  • Biker Mice from Mars: Eyemore from "Manchurian Charley", who can hypnotize people with his one, massive eye.
  • Butt-Ugly Martians features a race of overweight and one-eyed aliens called the Karsh.
  • Captain Sturdy: Back in Action villain Moid is a cycloptic alien.
  • ChalkZone: The magic chalk mine was originally guarded by a cyclops who wouldn't let anyone have any. The poor depth perception made him trip a lot, so as Rudy escaped with some of the chalk, he drew him a second eye above the first. When Rudy returns later, the cyclops, who now calls himself "Biclops", is actually very grateful for his improved vision, and lets Rudy take as much chalk as he wants.
  • SpongeBob SquarePants: Plankton, a small marine critter with a single eye. Truth in Television too; there's actually a genus of microscopic crustaceans called Cyclops (see the Real Life folder for more). One episode has him figure out that this is detrimental to his plans because he lacks depth perception. He spends the episode trying to grow a second eye through experiments, finally getting one via SpongeBob's DNA... but SpongeBob's naturally good personality begins to take over Plankton's and he ultimately has to get rid of it so he can continue his plans.
  • Steven Universe:
    • Sapphire is revealed to be one when her hair is moved out of her eye in the episode "Keystone Motel". The same applies to Padparadscha, an Off-Color orange Sapphire.
    • Centipeetle/Nephrite has her gem as a single, functional eye.
    • Emerald and Eyeball Ruby both have their gems where their eyes would otherwise be, thus giving each only one functional eye.
  • SWAT Kats:
    • "The Giant Bacteria": The way the title creatures work is that they divide or not depending on the number of eyes they have. The original monster has four, so it divides into two creatures with two eyes. These then have the potential to divide into a total of four single-eyed bacteria monsters, of which there wind up being two (animation errors aside).
    • "Bride of the Pastmaster": The Pastmaster uses a trio of huge kat cyclopes as part of his army of mythological monsters. Two of them have horned foreheads.
    • "Mutation City": The "scum snake" that drags the Turbokat down under the surface of the mutagen has one single cycloptic eyeball. T-Bone even exchanges glares with it through the cockpit - "What're you lookin' at, ugly?"
  • What It's Like Being Alone: Seymore Talkless, due to being a mutant, has one eye. He's also notable for being entirely mute.
  • Xiaolin Showdown has Cyclops, a giant, red, one-eyed creature similar in appearance to the ones from the Greek mythology. He is physically strong and can fire a laser beam from his eye, but he's also immature and Jack has to take care of him like a baby.

    Real Life 
  • Cyclopes aren't restricted to mythology — a number of defects in fetal development can result in the birth of one-eyed creatures, although the severity of these defects and related disorders means these creatures usually die soon after. Exposure to natural or man-made poisons is often to blame nowadays.
    • Cy, the internet-famous one-eyed noseless kitten, who was born December 2005 and died a day later.
    • A cyclops goat was also born in Nigeria. It caused quite a stir — they even accused the owner of an act of bestiality.
    • A one-eyed piglet with a severely deformed nose was also born in China in 2005.
    • Cyclopia, as it's known, can manifest in humans as well. You can Google it, but the pics can be rather squicky, so be warned. Most cyclopia babies don't survive more than a day or so after birth, if they're not stillborn.
  • The cyclopes from Greek legend are thought to have been based on a misconstrual of a fossilized mammoth or other prehistoric elephant skulls. If there were no tusks present, the trunk hollow could easily be mistaken for a single eye socket (it's actually the nasal cavity). You'd even have tourist travel guides telling travelers where they could see a cyclops's remains. This was especially true of dwarf elephants, which tended to have smaller or no tusks, and were common throughout the islands of the eastern Mediterranean during the Pleistociene, with most or all populations having gone extinct some time before humans were thought to have colonized the islands.
  • Anime blogger Danny Choo took a few pictures of someone dressed as a cute and fashionable little cyclops girl at the 2012 Wonder Festival. They were also spotted at the Tokyo Design Festa of the same year, always clad in the latest Harajuku fashion. So far they've never appeared again, and nobody knows if they were a part of some publicity stunt or just a fan of unusual cosplays.
  • Cyclops is a common genus of copepods (tiny crustaceans that range from 0.5 to 5 millimeters in size) found in freshwater environments around the world; they are easily identified by (you guessed it) their single large eye. They are harmless in and of themselves and form an important link in many aquatic food chains, but they can serve as intermediate hosts to some pretty nasty parasites (such as tapeworms and guinea worms). Plankton from Spongebob is based on these guys.

 
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Colored Contacts

Manako tries out various protective contact lenses, as getting things stuck in your eye is a common monoeye problem.

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