A list of actors and actresses with a TV Tropes page who have appeared in adaptations of/works inspired by Sir Arthur Conan Doyle's literary hero, the Great Detective Sherlock Holmes.
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Mystery Films
Sherlock Holmes (1922)
Appeared in Sherlock Holmes (1922):
- John Barrymore: Sherlock Holmes.
- William Powell: Forman Wells.
The Sign of Four (1932)
Appeared in The Sign of Four (1932):
- Ian Hunter: Dr. John H. Watson.
A Study in Scarlet (1933)
Appeared in A Study in Scarlet (1933):
- Anna May Wong: Mrs. Pyke.
Basil Rathbone Films (1939)
Appeared in The Hound of the Baskervilles (1939):
- Lionel Atwill: James Mortimer M.D.
- Also appeared as Moriarty in Sherlock Holmes and the Secret Weapon (1943)
- Nigel Bruce: Dr. John H. Watson.
- Voiced Watson in the radio dramas The New Adventures of Sherlock Holmes between 1939 and 1947.
- Samples of dialogue from his films were used in The Great Mouse Detective in 1986.
- John Carradine: Barryman.
- Basil Rathbone: Sherlock Holmes.
- Voiced Sherlock in the radio dramas The New Adventures of Sherlock Holmes between 1939 and 1946.
- Samples of dialogue from his films were used in The Great Mouse Detective in 1986.
Appeared in The Adventures of Sherlock Holmes (1939):
- Ida Lupino: Ann Brandon.
Appeared in Sherlock Holmes Faces Death (1943):
- Peter Lawford: Young Sailor at Bar.
The Hound of the Baskervilles (1959)
Appeared in The Hound of the Baskervilles (1959):
- Peter Cushing: Sherlock Holmes.
- Replaced Douglas Wilmer as Sherlock in the 1964-1968 TV series.
- Played Sherlock one more time in The Masks of Death (1984 TV film).
- Christopher Lee: Sir Henry Baskerville.
- Also played Sherlock in Sherlock Holmes and The Deadly Necklace (1962).
- Mycroft Holmes in The Private Life of Sherlock Holmes (1970).
- Sherlock again in the TV films Sherlock Holmes and the Leading Lady (1991) and Incident at Victoria Falls (1992).
A Study in Terror (1965)
Appeared in A Study in Terror (1965):
- Judi Dench: Sally Young.
- Donald Houston: Dr. John Watson.
- John Neville: Sherlock Holmes.
- Dr. Thorndyke in The Rivals of Sherlock Holmes.
- Dr. O. Henry in The Adventures of Shirley Holmes.
- Barbara Windsor: Annie Chapman.
The Private Life of Sherlock Holmes (1970)
Appeared in The Private Life of Sherlock Holmes (1970):
- Alex McCrindle: Baggageman.
- Frank Thornton: Porter.
The Seven-Percent-Solution (1976)
Appeared in The Seven-Per-Cent Solution (1976):
- Alan Arkin: Sigmund Freud.
- Charles Gray: Mycroft Holmes.
- Also played Mycroft in the 1984-1994 TV series.
- Eugene Valmont in The Rivals of Sherlock Holmes.
- Laurence Olivier: Moriarty.
- Vanessa Redgrave: Lola Devereaux.
Murder by Decree (1979)
Appeared in Murder by Decree (1979):
- John Gielgud: Lord Salisbury.
- James Mason: Dr. John Watson.
- Christopher Plummer: Sherlock Holmes.
- Donald Sutherland: Robert Lees.
The Masks of Death (1984)
Appeared in The Masks of Death (1984):
- Anton Diffring: Count Udo von Felseck.
Young Sherlock Holmes (1985)
Appeared in Young Sherlock Holmes (1985):
- Roger Ashton-Griffiths: Inspector Lestrade.
- Freddie Jones: Chester Cragwitch.
Robert Downey Jr. Film Series (2009-2011)
Appeared in Sherlock Holmes (2009):
- Robert Downey Jr.: Sherlock Holmes.
- William Houston: Constable Clark.
- Jude Law: Dr. John Watson.
- Joe Barnes in an episode of The Case-Book of Sherlock Holmes.
- Robert Maillet: Dredger.
- Eddie Marsan: Inspector Lestrade.
- Rachel McAdams: Irene Adler.
- Kelly Reilly: Mary Watson, née Morstan.
- Mark Strong: Lord Henry Blackwood.
Appeared in Sherlock Holmes: A Game of Shadows (2011):
- Stephen Fry: Mycroft Holmes.
- Vladimír Furdík: Andrzej.
- Jared Harris: Professor James Moriarty.
- Noomi Rapace: Simza Heron.
Sir Arthur Conan Doyle's Sherlock Holmes (2010)
Appeared in Sir Arthur Conan Doyle's Sherlock Holmes (2010)
- Dominic Keating: Thorpe Holmes
Mr. Holmes (2015)
Appeared in Mr. Holmes (2015):
- Roger Allam: Dr. Barrie.
- Frances Barber: Matinee 'Madame Schirmer'.
- Hermione Corfield: Matinee 'Ann Kelmot'.
- Michael Culkin: Bank Manager.
- The Judge in Holmes and Watson.
- Laura Linney: Mrs. Munro.
- Ian McKellen: Sherlock Holmes.
- Hiroyuki Sanada: Tamiki Umezaki.
Enola Holmes Film Series (2020—)
Appeared in Enola Holmes (2020):
- Adeel Akhtar: Inspector Lestrade.
- Millie Bobby Brown: Enola Holmes.
- Helena Bonham Carter: Eudoria Holmes.
- Henry Cavill: Sherlock Holmes.
- Sam Claflin: Mycroft Holmes.
- Burn Gorman: Linthorn.
- Louis Partridge: Viscount Tewkesbury.
Appeared in Enola Holmes 2 (2022):
- David Thewlis: Superintendent Grail
- Sharon Duncan-Brewster: Mira Troy AKA Moriarty
- Himesh Patel: Dr. John Watson.
Comedy/Parody Films
They Might Be Giants (1971)
Appeared in They Might Be Giants (1971):
- George C. Scott: Justin.
The Adventure of Sherlock Holmes' Smarter Brother (1975)
Appeared in The Adventure of Sherlock Holmes' Smarter Brother (1975):
- Mel Brooks: Voice of the lion victim.
- Dom De Luise: Eduardo Gambetti.
- Marty Feldman: Sgt. Orville Stanley Sacker.
- Albert Finney: Man in Audience at the opera.
- John Hollis: Moriarty's Gunman.
- Madeline Kahn: Jenny Hill.
- Leo McKern: Moriarty.
- Nicholas Smith: Hunkston.
- Solicitor in The Rivals of Sherlock Holmes.
- Gene Wilder: Sigerson Holmes.
The Hound of the Baskervilles (1978)
Appeared in The Hound of the Baskervilles (1978):
- Peter Cook: Sherlock Holmes.
- Norman Greenhough in Without a Clue.
- Denholm Elliott: Stapleton.
- Dr. Mortimer in The Hound of the Baskervilles (1983).
- Spike Milligan: Policeman.
- Dudley Moore: Watson/Mr. Spiggot/Mrs. Ada Holmes/Piano Player.
- Terry-Thomas: Dr. Mortimer.
- Kenneth Williams: Sir Henry Baskerville.
Without a Clue (1988)
Appeared in Without a Clue (1988):
- Lysette Anthony: Lesley Giles.
- Michael Caine: Reginald Kincaid.
- Jeffrey Jones: Inspector George Lestrade.
- Ben Kingsley: Dr. John Watson.
A Samba for Sherlock (2001)
Appeared in A Samba for Sherlock (O Xangô de Baker Street, 2001):
- Joaquim De Almeida: Sherlock Holmes.
Holmes & Watson (2018)
Appear in Holmes & Watson (2018):
- Rob Brydon: Inspector Lestrade.
- Steve Coogan: Gustav Klinger.
- Will Ferrell: Sherlock Holmes.
- Ralph Fiennes: Professor Moriarty.
- Rebecca Hall: Dr. Grace Hart.
- Lauren Lapkus: Millie.
- Hugh Laurie: Mycroft Holmes.
- Kelly Macdonald: Rose Hudson.
- Bella Ramsey: Flotsam.
- John C. Reilly: John Watson.
- Braun Strowman: Brawn.
- Billy Zane: Himself
TV Productions
Sherlock Holmes (1954-1955)
Appeared in Sherlock Holmes (1954-1955):
- Duncan Elliott: Mr. Ross / Uncle Cecil / J. Oliver / Jack Driscol.
The Elgin Hour - "Sting of Death" (1955)
Appeared in The Elgin Hour - "Sting of Death" (anthology series episode, 1955):
- Boris Karloff: Sherlock Holmes.
Sherlock Holmes (1964-1968)
Appeared in Sherlock Holmes (1964-1968):
- Roger Delgado: Moser.
- Silva in The Rivals of Sherlock Holmes.
- Walter Gotell: Henderson.
- Patrick Troughton: Mortimer Tregennis.
- Peter Wyngarde: Baron Grüner.
- Langdale Pike in the 1984-1994 TV series.
The Rivals of Sherlock Holmes (1971)
Appeared in The Rivals of Sherlock Holmes (1971):
- Peter Barkworth: Martin Hewitt.
- Colonel Ross in the 1984-1994 TV series.
- David Battley: Podgers.
- Richard Beckinsale: Richard Frobisher.
- Nicholas Courtney: Hutchinson Hatch.
- Brenda Cowling: Maid.
- Sarah Craze: Rose.
- Paul Darrow: Dr. Hart.
- Windsor Davies: Inspector Illingworth.
- Roger Delgado: Silva.
- Leslie Dwyer: Lost Property Man.
- Paul Eddington: Hamer.
- Derek Francis: Dixon.
- Julian Glover: Alfred Barton.
- Michael Gough: Governor.
- Charles Gray: Eugene Valmont.
- Jeremy Irons: Nephew George.
- Derek Jacobi: William Drew.
- Martin Jarvis: Philip Marsden.
- Caroline John: Edith Dallas.
- Laura Lyons in The Hound of the Baskervilles (1982)
- John Levene: Constable.
- Philip Madoc: Dimitri Wolkinski.
- Jean Marsh: Mrs. Vanrenen.
- Christopher Neame: Sydney Wing.
- John Neville: Dr. Thorndyke.
- Michael Nightingale: Harkness.
- Nicola Pagett: Countess Nadja.
- Jacqueline Pearce: Jenny Pryde
- Donald Pleasence: Carnacki.
- Jo Rowbottom: Suzie Shepherd.
- Catherine Schell: Maria Wolkinski.
- Michael Sheard: Dr. Jones.
- John Thaw: Lt. Holst.
- Peter Vaughan: Horace Dorrington.
The Hound of the Baskervilles (1972)
Appeared in The Hound of the Baskervilles (1972):
- Stewart Granger: Sherlock Holmes.
- William Shatner: George Stapleton.
- John Williams (actor): Arthur Frankland.
Dr. Watson and the Darkwater Hall Mystery (1974)
Appeared in Dr. Watson and the Darkwater Hall Mystery (1974):
- Edward Fox: Dr. Watson.
- Alistair Ross in The Crucifier of Blood.
Sherlock Holmes in New York (1976)
Appeared in Sherlock Holmes in New York (1976):
- David Huddleston: Inspector Lafferty, NYPD.
- John Huston: Professor Moriarty.
- Patrick Macnee: Dr. John Watson.
- Reprised the role of Watson in the TV films Sherlock Holmes and the Leading Lady (1991) and Incident at Victoria Falls (1992) alongside Christopher Lee's Holmes.
- Played Holmes in the TV film The Hound of London (1993).
- Roger Moore: Sherlock Holmes.
- Charlotte Rampling: Irene Adler.
- Gig Young: Mortimer McGrew.
The Strange Case of the End of Civilization as We Know It (1977)
Appeared in The Strange Case of the End of Civilization as We Know It (1977):
- John Cleese: Arthur Sherlock Holmes.
- Ron Moody: Dr. Henry Gropinger.
The Hound of the Baskervilles (1982)
Appeared in The Hound of the Baskervilles (1982):
- Tom Baker: Sherlock Holmes.
Young Sherlock: The Mystery of the Manor House (1982)
Appeared in Young Sherlock: The Mystery of the Manor House (1982):
- Guy Henry: Sherlock Holmes.
- Mr. Bilney in Sherlock Holmes and the Case of Silk Stocking (2004).
The Hound of the Baskervilles (1983)
Appeared in The Hound of the Baskervilles (1983):
- Glynis Barber: Beryl Stapleton.
- BRIAN BLESSED: Geoffrey Lyons.
- Eleanor Bron: Mrs. Barrymore.
- Denholm Elliott: Dr. Mortimer.
- Ian Richardson: Sherlock Holmes.
- Kerry Shale: Sir Henry.
- Leverton in The Memoirs of Sherlock Holmes.
- Sherlock Holmes in The Testament of Sherlock Holmes.
- Martin Shaw: Sir Henry Baskerville.
The Masks of Death (1984)
Appeared in The Masks of Death (1984):
- Anne Baxter: Irene Adler.
- Ray Milland: Home Secretary.
- John Mills: Dr. John Watson.
Sherlock Holmes (1984-1994)
Appeared in Sherlock Holmes (1984-1994):
- Claudine Auger: Isadora Klein.
- Jeremy Brett: Sherlock Holmes.
- Kenneth Connor: Mr. Warren.
- Alastair Duncan: Dr. Mortimer.
- Jon Finch: Count Sylvius.
- Peter Guinness: Jenkins.
- Robert Hardy: Charles Augustus Milverton.
- Ciarán Hinds: Jim Browner.
- Jonathan Hyde: Culverton Smith.
- George Pentney in The Case of the Silk Stocking.
- Michael Jayston: The Earl of Rufton.
- Tim McInnerny: John Clay.
- Sir Eustace Carmichael in Sherlock.
- Wolf Kahler: Wilhelm von Ormstein, King of Bohemia.
- Dr. Hoffmanstahl in Sherlock Holmes: A Game of Shadows.
- Catherine Rabett: Young Nancy.
- Natasha Richardson: Violet Hunter.
- Marina Sirtis: Lucrezia Venucci.
- Fiona Shaw: Miss Morrison.
- Miss Harrison in Enola Holmes.
- Malcolm Storry: Inspector Gregory.
- Eric Sykes: Horace Harker.
- Gareth Thomas: Joseph Harrison
- Steve Toussaint: Steve Dixie.
- Richard Wilson: Duncan Ross.
The Return of Sherlock Holmes (1987)
Appeared in The Return of Sherlock Holmes (1987):
- Daniel Benzali: Ross.
- Margaret Colin: Joan Watson.
- Terence Longdon: Isa Whitney.
- Barry Morse: Carter Morstan.
The Hound of the Baskervilles (1988)
Appeared in The Hound of the Baskervilles (1988):
- Kristoffer Tabori: Sir Henry Baskerville.
Hands of a Murderer (1990)
Appeared in Hands of a Murderer (1990):
- Edward Woodward: Sherlock Holmes.
The Crucifer of Blood (1991)
Appeared in The Crucifer of Blood (1991):
- Edward Fox: Alastair Ross
- Charlton Heston: Sherlock Holmes.
The Adventures of Shirley Holmes
Appeared in The Adventures of Shirley Holmes (1997-2000):
- Roger Cross: Colonel Nyandwi.
- Anthony De Longis: Vern.
- Richard McMillan: Rudy Pike.
- Matthew Walker: Shepherd.
Sherlock: Case of Evil (2002)
Appeared in Sherlock: Case of Evil (2002):
- Gabrielle Anwar: Rebecca Doyle
- James D'Arcy: Sherlock Holmes.
- Vincent D'Onofrio: Moriarty.
- Richard E. Grant: Mycroft Holmes.
- Jack Stapleton in The Hound of the Baskervilles (2002).
The Hound of the Baskervilles (2002)
Appeared in The Hound of the Baskervilles (2002):
- Ian Hart: Dr. John Watson.
- Prof. Baynes in Elementary.
- Neve McIntosh: Beryl Stapleton.
- Jim Norton (actor): Coroner.
- Sir James Walter in Elementary.
Sherlock Holmes and the Case of the Silk Stocking (2004)
Appeared in Sherlock Holmes and the Case of the Silk Stocking (2004):
- Tamsin Egerton: Miranda Helhoughton.
- Rupert Everett: Sherlock Holmes.
- Michael Fassbender: Charles Allen.
- Ian Hart: Dr. Watson.
- Jonathan Hyde: George Pentney.
- Helen McCrory: Mrs. Vandeleur.
- Perdita Weeks: Roberta Massingham.
The Baker Street Irregulars (2007)
Appeared in Sherlock Holmes and the Baker Street Irregulars (2007):
- Aaron Johnson: Finch.
- Jonathan Pryce: Sherlock Holmes.
Sherlock (2010-2017)
Appeared in Sherlock (2010-2017):
- Amanda Abbington: Mary Morstan.
- Jonathan Aris: Philip Anderson.
- Louise Brealey: Molly Hooper.
- Gemma Chan: Soo Lin Yao.
- Oona Chaplin: Jeanette.
- Benedict Cumberbatch: Sherlock Holmes.
- Phil Davis: The Taxi Driver/Jeff.
- Inspector Gilbert in Mr. Holmes.
- Peter Davison: Planetarium Voiceover.
- Sacha Dhawan: Ajay.
- Martin Freeman: Dr. John Watson.
- Mark Gatiss: Mycroft Holmes.
- Rupert Graves: Inspector G. Lestrade.
- Stephanie Hyam: Jane.
- Ralph Ineson: Vince.
- Toby Jones: Culverton Smith.
- Will Keen: Major Reed.
- Eleanor Matsuura: Detective Inspector Stella Hopkins.
- Lars Mikkelsen: Charles Augustus Magnussen.
- Matthew Needham: Bezza.
- Natasha O'Keeffe: Emilia Ricoletti.
- Katherine Parkinson: Kitty Riley.
- Lara Pulver: Irene Adler.
- Vinette Robinson: Police Sergeant Sally Donovan.
- Andrew Scott: Professor Jim Moriarty.
- Will Sharpe: Corporal Lyons.
- Russell Tovey: Henry Knight.
- Wanda Ventham: Mrs. Holmes
Elementary (2012-2019)
Appeared in Elementary (2012-2019):
- Greg Abbey: Daren.
- F. Murray Abraham: Daniel Gottlieb.
- Shohreh Aghdashloo: Liliane Bellerose.
- Gbenga Akinnagbe: Jeremy Lopez.
- Nadia Alexander: Hope Neligan.
- Bruce Altman: Dr. Jonathan Fleming.
- Vincenzo Amato: Guillaume de Soto.
- Happy Anderson: Nick Farris.
- Yancey Arias: Robert Castillo.
- Rosa Arredondo: Elaine.
- Lisa Arrindell: Ethiopian Consul.
- Ashlie Atkinson: Gay.
- Kelly AuCoin: Grey Suit.
- Reiko Aylesworth: Miranda Molinari.
- Becky Ann Baker: Pam.
- David Aaron Baker: Joe Leshner.
- Alimi Ballard: Don Kohler.
- Talia Balsam: Cheryl Gregson.
- Roger Bart: Kip Lowell.
- Rob Bartlett: Capt. Dwyer.
- David Alan Basche: Warren Clift.
- Chris Bauer: Det. Gerry Coventry.
- Noelle Beck: Peri Delancey.
- Richard Bekins: Harold Dresden.
- Liza J. Bennett: Hannah Gregson.
- Emily Bergl: Marion West.
- Casey Biggs: Alan Becker.
- Marsha Stephanie Blake: Melanie Cullen.
- Susan Blommaert: Dr. Xanthopoulos.
- Jeremy Bobb: Agent Gary Burke.
- Eric Bogosian: Chris Bauer.
- John Bolger: David Batonvert.
- Mark Boone Junior: Guitar Expert.
- Dennis Boutsikaris: Gerald Lydon.
- Patrick Breen: Vance Ford.
- Will Brill: Tyler Eggert.
- Richard Brooks: Det. Demps.
- Brennan Brown: Kevin Elspeth.
- Roger Aaron Brown: John Douglas.
- Cara Buono: Sarah Cushing.
- Heather Burns: Chloe Butler.
- Saffron Burrows: Ruby Carville.
- Danny Burstein: Ted Winthrop.
- Megan Byrne: Doctor.
- Paul Calderón: Zuniga.
- Robert Capron: Mason.
- Victoria Cartagena: Hope.
- Philip Casnoff: Jack McGill.
- Candis Cayne: Ms. Hudson.
- Fulvio Cecere: Dante Scalice.
- Michael Cerveris: Councilman Ledesma.
- Sarita Choudhury: Gira Pal.
- Scott Cohen: Nolan Sharp.
- John Ellison Conlee: Kirk Abramovitch.
- Josh Cooke: Phil Balsam.
- David Corenswet: Houston Spivey.
- Daniel Cosgrove: Len.
- David Costabile: Danilo Gura.
- Shamika Cotton: Rose.
- Christina Cox: Christa Pullman.
- Tony Crane: Everett Keck.
- Michael Cristofer: Isaac Pyke.
- Monique Gabriela Curnen: Det. Gina Cortes.
- Tony Curran: Joshua Vikner.
- Olivia D Abo: Nigella Mason.
- Nadia Dajani: Dr. Grannis.
- Brett Dalton: Ryan Hayes.
- Patch Darragh: Griffin Parker.
- Jeremy Davidson: Gordon Cushing.
- Daniel Davis: Antoine LaGrange
- Rebecca Dayan: Fabiana.
- Matthew Del Negro: Nathan Resor.
- Anthony DeSando: Peter Dinacio.
- Melissa De Sousa: Luz Horowitz.
- Reed Diamond: Joel Fitzgerald.
- Garret Dillahunt: Bart MacIntosh.
- Erin Dilly: Amanda Kemper.
- Brandon J. Dirden: Agent Polk.
- John Doman: Councilman Slessinger.
- Tate Donovan: Wilson Trager.
- Natalie Dormer: Irene Adler/Moriarty.
- John Dossett: Treadwell.
- Mike Doyle: Chris Holland.
- Pamela Dunlap: Esther Kelton.
- Trieste Kelly Dunn: Sophie Bishop.
- Wayne Duvall: Duke Landers.
- Lisa Edelstein: Heather Van Owen.
- Ned Eisenberg: Marvin Hathaway.
- Linda Emond: Dr. Candace Reed.
- Kathryn Erbe: Nancy Davenport.
- Siobhan Fallon Hogan: Sylvia Kozar.
- Gene Farber: Janko Stepovic.
- Melissa Farman: Carly Purcell.
- Glenn Fleshler: Trey McCann.
- Jill Flint: Alysa Darvin.
- James Frain: Odin Reichenbach.
- K. Todd Freeman: Raphael.
- Paula Garces: Paula Reyes.
- Michael Gaston: Kurt Yoder.
- Jordan Gelber: Dr. Eugene Hawes.
- Brian George: Santhosh.
- Peter Gerety: Frank Da Silva.
- Gina Gershon: Elana March.
- Seth Gilliam: Dr. Ira Wallace.
- Maury Ginsberg: Keating.
- Michael Gladis: Rodger Stapleton.
- Adam Godley: British Man.
- Natalie Gold: Sarah Penley.
- Malcolm Goodwin: Andre Bell.
- Zabryna Guevara: Det. Lisa Hagen.
- Tim Guinee: NSA Agent Dean McNally.
- Mamie Gummer: Margaret Bray.
- Murphy Guyer: Det. Whitaker.
- Jack Gwaltney: Homicide Detective.
- Josh Hamilton: Drew Gardner.
- LisaGay Hamilton: Lt. Col. Robin Deakins.
- John Hannah: Rhys.
- David Harbour: Dr. Mason Baldwin.
- Amy Hargreaves: Jill Horowitz.
- Jason Butler Harner: Ballard Clifton.
- Desmond Harrington: Michael.
- Frank Harts: Eddy Dunbridge.
- Steven Hauck: Crabtree.
- John Heard: Henry Watson.
- Leslie Hendrix: Cynthia Kerr.
- Peter Hermann: Det. Craig Basken.
- Jon Michael Hill: Det. Marcus Bell.
- Rachel Hilson: Lexi.
- Jackie Hoffman: Female Activist.
- Joe Holt: Eric Minton.
- James Hong: Meng Zhou.
- Jayne Houdyshell: Carla.
- Brian Hutchison: Kurt Godwyn.
- Rhys Ifans: Mycroft Holmes.
- Michael Irby: Xande Diaz.
- Bill Irwin: Richard Balsille.
- Vinnie Jones: Sebastian Moran.
- Hubert Point-Du Jour: Jaylen Thomas.
- Ian Kahn: Alwyn Smith.
- Brian Kerwin: Charles Cooper.
- Donnie Keshawarz: Earl Wheeler.
- Kevin Kilner: Michael Haas.
- Randall Duk Kim: Old Man.
- Richard Kind: Trent Garby.
- Terry Kinney: Howard Ennis.
- Luke Kirby: Aaron Ward.
- Michael Kostroff: Perry Franklin.
- Fran Kranz: Brendan Farley.
- Stephen Kunken: Dr. Carrow.
- Stephanie Kurtzuba: Eileen Rourke.
- Dan Lauria: Louis Garmendia.
- Katrina Lenk: Sonia.
- Conor Leslie: Molly Parsons.
- Lucy Liu: Joan Watson (née Yeun).
- John Bedford Lloyd: Lieutenant.
- Jodi Long: Mrs. Tseng.
- Deirdre Lovejoy: Carrie Traub.
- Ophelia Lovibond: Kitty Winter.
- J. C. MacKenzie: Daren Sutter.
- Elizabeth Marvel: Cassandra Walker.
- Meat Loaf: Herman Wolf.
- Virginia Madsen: Paige Cowen.
- Mark Margolis: Abraham Misraki.
- James Martinez: Diego Salcedo.
- Danny Mastrogiorgio: James Dylan.
- Kari Matchett: Kathryn Drummand.
- Dakin Matthews: James Connaughton.
- Joseph Mazzello: Griffin.
- LeRoy McClain: Gabe Acosta.
- Carolyn McCormick: Denise Davis.
- Chris McGarry: Agent Vince Boden.
- Michael McGlone: Lloyd.
- Matt McGorry: Officer Sam Klecko.
- Sam McMurray: Cameron Maranek.
- Marc Menchaca: Det. Ryan Dunning.
- Jonny Lee Miller: Sherlock Holmes.
- Susan Misner: Loretta Nichols.
- Haviland Morris: Dr. Jane Mortimer.
- Mark Moses: Oliver Purcell.
- Michael Mosley: Al Baxter.
- Michael Mulheren: Detective.
- Parminder Nagra: Special Agent Mallik.
- Marissa Neitling: Nina Hudgins/Skyler.
- John Noble: Morland Holmes.
- Gabriel Olds: Dr. Nate Campbell.
- Peter Onorati: Gio Bianchi.
- Zak Orth: Gabe Coleman.
- Geoffrey Owens: Vernon Fisk.
- Patrick Page: Jonathan Bloom.
- Maulik Pancholy: Alfonse Kapoor.
- Steve Park: Oren Watson.
- Paige Patterson: Businesswoman.
- Donald Paul: Socks.
- Miguel Perez: Priest.
- Sean Pertwee: Inspector Lestrade.
- Annika Peterson: Charlotte Klemmer.
- Jim Piddock: Tom Saunders.
- Tonya Pinkins: Judge Marilyn Whitfield.
- Jacob Pitts: Paul Ladesma.
- Richard Portnow: Eddie Eichorn.
- Michael Potts: Dr. Peter Hanson.
- Linda Powell: Congresswoman Salazar.
- Molly Price: Donna Kaplan.
- Aidan Quinn: Captain Tommy Gregson.
- Luis Antonio Ramos: Father Vega.
- Matthew Rauch: Garrett Lerner.
- Roger Rees: Alistair Moore.
- Ron Rifkin: Wayne Vachs.
- Robert Christopher Riley: Roy Booker.
- Jonno Roberts: Jerome Thomas.
- Roger Robinson: Bruce Kushner.
- Anika Noni Rose: Dr. Carrie Dwyer.
- Alan Rosenberg: Sydney Garber.
- Adam Rothenberg: Liam Danow.
- William Sadler: Ian Gale.
- Otto Sanchez: Renny Trautman.
- Julian Sands: Jasper Wells.
- Aaron Schwartz: Jersey Shore.
- Eric Schweig: Leon Moody.
- Tom Everett Scott: Henry Baskerville.
- Geno Segers: Fetu.
- Charlie Semine: Stewart Pringle/Wilson Kubiak.
- Terry Serpico: Wallace Turk.
- Matt Servitto: Captain Will Lombardi.
- Jeremy Shamos: Dr. Paul Sutherland.
- John Sharian: George Eagen.
- John Shea: Bill Wellstone.
- Leslie Silva: ATF Agent Hernan.
- Johnny Simmons: Adam Kemper.
- Felix Solis: Prentice Gutierrez.
- Rich Sommer: Harlan Emple.
- Paul Sorvino: Robert Pardillo.
- Stephen Spinella: Merrick Hausmann.
- Mike Starr: Russell Gertz.
- Fisher Stevens: Marty Ward.
- Skipp Sudduth: William Hull.
- Tara Summers: Nurse.
- Elizabeth Sung: Bai May-Lung.
- Keith Szarabajka: Wade Crewes.
- Babak Tafti: Jonathan Dawson.
- Brian Tarantina: Walsh.
- Christine Taylor: Gail Lundquist.
- Regina Taylor: Dr. Wilkerson.
- Simon Templeman: Ronald Adair.
- Richard Thomas: Mitch Barrett.
- Al Thompson: Bonzi Folsom.
- Kenneth Tigar: Philip Armistead.
- Stuart Townsend: Del Gruner.
- Jim True-Frost: Anson Samuels.
- Tamara Tunie: Lily Cooper.
- James Urbaniak: Dr. Leo Demopoulos.
- David Valcin: Osweiler.
- Yul Vazquez: Arthur Tetch.
- John Ventimiglia: Harry Magarac.
- Elliot Villar: Christian Suarez.
- Arnold Vosloo: Christos Theophilus.
- Sonya Walger: Angela White.
- Craig Walker: Peter Saldua.
- Jake Weber: Geoffrey Silver.
- Fred Weller: Ronnie Wright.
- Frank Whaley: Winston Utz.
- Jefferson White: Dorian Moll.
- Victor Williams: Jon Hoyt.
- Wade Williams: Ryan Decker.
- Afton Williamson: Shauna Scott.
- Frank Wood: EROC Supervisor.
- Tom Wopat: Soble.
- Sarah Wynter: Beth Roney.
- Rachel York: Carla Giovanni.
- Damian Young: Special Agent Breslin.
- Dan Ziskie: Gordie Kasdan.
The Irregulars (2021)
Appeared in The Irregulars (2021):
- Edward Hogg: Daimler.
- Rory McCann: Arthur Hilton / The Bird Man.
- Clarke Peters: The Linen Man.
Animation
The Sign of Four / The Baskerville Curse / A Study in Scarlet / Valley of Fear (1983-1984)
Appeared in The Sign of Four, The Baskerville Curse, A Study in Scarlet and Valley of Fear (1983-1984):
- Peter O'Toole: Sherlock Holmes.
Sherlock Hound (1984-1985)
Appeared in Sherlock Hound (1984-1985):
- Chikao Ohtsuka: Professor Moriarty.
The Great Mouse Detective (1986)
Appeared in The Great Mouse Detective (1986):
- Charles Fleischer: Uncredited voice.
- Vincent Price: Professor Ratigan.
- Frank Welker: Toby. Also voiced Felicia.
- Alan Young: Hiram Flaversham.
Sherlock Holmes in the 22nd Century (1999-2001)
Appeared in Sherlock Holmes in the 22nd Century (1999-2001):
- Vincent Gale: Various voices.
- Merrilyn Gann: Various.
- Jason Gray-Stanford: Sherlock Holmes.
- Richard Newman: James Moriarty.
- Gerard Plunkett: Various voices.
Tom and Jerry Meet Sherlock Holmes (2010)
Appeared in Tom and Jerry Meet Sherlock Holmes (2010):
- Malcolm McDowell: Professor Moriarty.
- John Rhys-Davies: Dr. Watson.
- Michael York: Sherlock Holmes.
Sherlock Gnomes (2018)
Appeared in Sherlock Gnomes (2018):
- Mary J. Blige: Irene.
- Jamie Demetriou: Moriarty.
- Johnny Depp: Sherlock Gnomes.
- Chiwetel Ejiofor: Gnome Watson.
- Dan Starkey: Teddy Gregson.
Case File nº221: Kabukicho (2019-2020)
Appeared in Case File nş221: Kabukicho (2019-2020):
- Daisuke Kishio: Gregory Lestrade
- Katsuyuki Konishi: Sherlock Holmes
- Yūichi Nakamura: Dr. John H. Watson
- Ryōtarō Okiayu: Mycroft Holmes
- Maaya Sakamoto: Irene Adler
- Jun'ichi Suwabe: "Mrs." Hudson
- Nao Tōyama: Mary Morstan
- Seiichirō Yamashita: James Moriarty
Moriarty the Patriot (2020-2021)
Appeared in Moriarty the Patriot (2020-2021):
Japanese:
- Soma Saito: Professor William James Moriarty
- Chiaki Kobayashi: Louis James Moriarty
- Takuya Sato: Lieutenant Colonel Albert James Moriarty
- Makoto Furukawa: Sherlock Holmes
- Yuki Ono: Dr. John H. Watson
- Satoshi Hino: Colonel Sebastian Moran
- Yūto Uemura: Fred Porlock
- Kosuke Toriumi: Von Herder
- Yōko Hikasa: Irene Adler
- Hiroki Yasumoto: Secretary Mycroft Holmes
- Kana Asumi: Ms. Hudson
- Fuminori Komatsu: Insepctor George Lestrade
- Kenji Nojima: Charles Augustus Milverton
English:
- Aaron Dismuke: Professor William James Moriarty
- Chris Guerrero: Lieutenant Colonel Albert James Moriarty
- Theo Devaney: Sherlock Holmes
- Christopher Wehkamp: Colonel Sebastian Moran
- J. Michael Tatum: Secretary Mycroft Holmes
- Suzie Yeung: Ms. Hudson
- David Matranga: Inspector George Lestrade
Radio
The Mercury Theater on the Air – "The Immortal Sherlock Holmes" (1938)
Appeared in The Mercury Theater on the Air – "The Immortal Sherlock Holmes" (CBS, 1938):
- Orson Welles: Sherlock Holmes.
Foreign Dubbings
European French
- Georges Aminel: Robert Lees in Murder by Decree.
- Adrien Antoine: Sherlock Holmes in Enola Holmes.
- Féodor Atkine: Mycroft Holmes in Holmes & Watson.
- Anatole de Bodinat: Mycroft Holmes in Enola Holmes.
- Patrick Borg: Inspector Lestrade in Sherlock Holmes (2009).
- Kurt Yoder in Elementary.
- Laurence Bréheret: Eudoria Holmes in Enola Holmes.
- Roger Carel: Sir Charles Warren in Murder by Decree.
- Moriarty (episode 6 only) / Willy's Grandfather in Sherlock Hound.
- Basil of Baker Street in The Great Mouse Detective.
- Marc Cassot: Sherlock Holmes in The Private Life of Sherlock Holmes.
- Bernard Gabay: Sherlock Holmes in Sherlock Holmes (2009) and Sherlock Holmes: A Game of Shadows.
- Professor James Moriarty in Holmes & Watson.
- Vincent Grass: Bartholomew in The Great Mouse Detective.
- Dr. Watson in Tom and Jerry Meet Sherlock Holmes.
- Gérard Hernandez: Moriarty (main voice) / Mr. Pocus / Mr. Brighton / The Maharadjah in Sherlock Hound.
- Éric Herson-Macarel: Lord Henry Blackwood in Sherlock Holmes (2009).
- Raymond Loyer: Mycroft Holmes in The Private Life of Sherlock Holmes.
- Theatre gatekeeper in Sherlock Holmes in New York.
- Patrick Poivey: Gareth Lestrade in Elementary.
- Michel Papineschi: Bill Wellstone in Elementary.
- Perrette Pradier: Queen Mousetoria in The Great Mouse Detective.
- William Sabatier: Mycroft Holmes in The Seven-Per-Cent Solution (1976).
- Chief Inspector Graysson in Sherlock Holmes in the 22nd Century.
- Barbara Tissier: Olivia Flaversham in The Great Mouse Detective.
