Only spoilers from The Final Chapter are whited out.
- "My name is Alice. And I remember everything."
The central protagonist of the film franchise.
- Action Girl: She wins nearly every fight she's in with ease.
- Alice Allusion: Her name is a Shout-Out to Alice's Adventures in Wonderland. The first film has some references to it
- Amnesiac Hero: Throughout most of the first film.
- Apologetic Attacker: She beats Nemesis one-on-one by running him through on a metal shard... after which she realizes that he is the mutated Matt Addison and profusely apologizes.
- Badass Biker: She uses a bike as her main source of transportation throughout the third film.
- Badass Longcoat: During the third film.
- Badass Normal: During the first, fourth, and fifth films.
- Bare Your Midriff: In the second film.
- Brought Down to Badass: After losing her powers during the fourth film. Wesker gives them back at the end of the fifth film. But then in the sixth film, it's revealed she didn't actually get her powers back.
- Canon Foreigner: Not in the games and made entirely for the film franchise.
- Cloning Blues: Umbrella cloned her constantly in the hope of replicating her powers and building an army. The Final Chapter reveals that she's a clone herself. Specifically of Alicia Marcus, the daughter of the original co-founder of Umbrella, James Marcus.
- Cursed with Awesome: Has this attitude towards her T-virus powers, even explicitly telling Jill Valentine that she barely feels human anymore. It gets to the point where, when she's depowered by Wesker in Resident Evil: Afterlife, she actually thanks him for doing so. At the end of Resident Evil: Retribution, he seems to give them back. In Resident Evil: The Final Chapter, it's revealed Wesker lied about giving back her powers.
- Deadpan Snarker: Usually drops a few lines upon meeting another character for the first time, or when fighting an enemy.(when Carlos reveals that he is infected and she has the cure) This is your lucky day.(when Claire requests Alice to remove her cuffs) Not until we know each other for a little longer.(when the Executioner Majini accidentally cut a gas tank) Boys, bad idea. (makes nearby car explode)
- Dual Wielding: Uses two kukris in the third film.
- Empowered Badass Normal: After her T-virus infection.
- Gender-Blender Name: Janus (Alice's real name) is a masculine name. It's also name of the Roman god of gates, doors, doorways, beginnings, and endings.
- Guns Akimbo: One gun in each hand in the second film.
- I Have Many Names: Has gone by Alice Parks, Alice Abernathy and Janus Prospero. In the last film, her real name (or rather the person she was cloned from) is revealed: Alicia Marcus.
- Invincible Hero: She seems to win every fight without any problem. Pretty much overshadows all the other characters. Averted with the fifth movie when her and Jill fight and she gets knocked around like a rag doll; she only barely wins it by pulling the mind control device off her chest just before Jill is about grate her against an overturned tank tread.
- Kukris Are Kool: She dual wields kukri knives in the third film.
- Mama Bear: Develops this sort of relationship with Becky, to the point that when a giant Licker kidnaps her, she goes off to find her.
- Made of Iron: Even after losing her powers and being Brought Down to Normal, Alice is still able to walk away from a massive VTOL crash-explosion and suffer a brief bout of unconsciousness after getting smashed across the room with a giant hammer. Additionally, she quickly shrugs off being impaled through the wrist by a large blade during the fight with Wesker on the ''Arcadia'. On top of it all, during the final fight of the fifth film, she survives and manages to shake off a sternum-cracking palm strike from Bad Rain that killed Luther West.
- Male Gaze: There are a lot of close up shots of her legs in the first film.
- Murderous Thighs: That lucky, lucky zombie in the first film.
- No-Sell: She did not react to the taser that struck her when she first awakened to her powers in the second film.
- One-Woman Army: Takes down tons of zombies by herself in the second, third, fourth and fifth films.
- Psychic Powers: Develops telekinesis and possible Technopathy (as well as, impliedly, some degree of Telepathy) after being infected with the T-virus.
- Schrödinger's Canon: Regarding her name. Promotional materials state Alice Abernathy is a fake identity, some of them even suggesting that Janus Prospero is her real name, but the novelization of Apocalypse states Alice Abernathy is her real name and Janus Prospero the fake one (the film itself leaves it ambiguous). The Final Chapter then reveals both of them are technically fake, as she is a clone of Alicia Marcus.
- She's Got Legs: In the first film. The camera is kept as low as possible in the film to show off her legs.
- Spider-Sense: The first real power Alice develops, being able to tell if anyone's been infected even if dormant.
- Spotlight-Stealing Squad: In Apocalypse, which ostensibly is based on Resident Evil 3: Nemesis, Alice is portrayed as the most competent, powerful, and prominent character at the cost of making RE3's main character, Jill Valentine, an Adaptational Wimp. This effectively sets the tone for the rest of the film series, where none of the characters from the games can ever hope to do anything even remotely important or even act like a competent person in comparison to her.
- Spy Catsuit: in Resident Evil: Retribution. 'Good' Rain wonders why she's wearing an S&M outfit.
- Token Super: She became this for her La Résistance team after contracting the T-virus but with it instead granting her powers rather than the zombie degeneration.
- Tranquil Fury: Her voice barely ever rises above a dull monotone, but you can tell when she's pissed.
An evil program that's a hologram of a little girl based off of Angela Ashford, later retconned as based off of Alicia in the final film.
- AI Is A Crap Shoot: Subverted. She was programmed to ensure that any viral outbreaks never left the Hive facility, so when the T-Virus was released, she locked down the facility and killed all inhabitants to ensure that it couldn't leave. The only reason the infection does spread to the rest of the world was that because the massively incompetent Umbrella Corporation couldn't leave well enough alone, and sent in a strike team to bungle around inside. Four sequels later, however, the now-back online Red Queen is playing this very straight. Having seized control of Umbrella, she is now attempting to wipe out all life on Earth For the Evulz. Then in The Final Chapter it turns out she's just following the orders of the original Dr. Isaacs, though she does end up turning against him upon learning that he planned the outbreak from the very beginning in order to cleanse the Earth.
- Adapted Out: In the novelization of Retribution.
- Big-Bad Ensemble: In the first film she is one of the Big Bads, being the one responsible for sealing the Hive and murdering its workers in order to prevent the virus outbreak (which was caused by the other Big Bad, Spence) from escaping The Hive.
- Canon Immigrant: Initially a Canon Foreigner, she makes an appearance in Resident Evil: The Umbrella Chronicles, which contains a few references to the films.
- Creepy Child: The holographic representation of her is a small girl, modeled after Angela Ashford.
- Enfant Terrible: In a way since she is a villain to the protagonists, but she's not really a child.
- Evil Brit: Her voice has a British accent.
- Hijacked by Ganon: In Retribution.
- Hologram: She is actually a program, but she can project a holographic representation of herself.
- Necessarily Evil: The Red Queen qualifies big time. Yes, she did murder the entire Umbrella research facility staff, but she was only following her main directive to prevent a T-Virus outbreak. Her actions are probably the most sensible out of anyone in the entire series when it comes to containing a T-Virus outbreak. Her actions are brutal, but effective at least until Umbrella unseals the facility and lets all the zombies loose. When the series hits the fifth film, however, she seems to have gone full-on evil.
- Restraining Bolt: She's forbidden to harm employees of the corporation, outside of cases like infection by the T-Virus.
- Well-Intentioned Extremist: In the first movie, as she tried to stop a viral outbreak. By killing all the inhabitants of the Hive facility to prevent it from leaving. Later films reveal that she was right...
- Zeroth Law Rebellion: She's programmed to be incapable of directly causing harm to Umbrella employees, but also to value human life. When the two conflict, she can put Alice in a position to act against Umbrella herself.
- Ambition Is Evil: He'll stop at nothing to rise to the top, no matter who he has to murder to get there.
- And Then John Was a Zombie: In Extinction, Isaacs get bitten by one of his enhanced zombies and starts to mutate, eventually becoming a Tyrant.
- Back from the Dead: Returns as the Big Bad of Resident Evil: The Final Chapter, as the first Dr. Isaacs was actually just a clone.
- Big Bad: in Resident Evil: Extinction, though it turns out he was actually a clone. The real Dr. Isaacs appears in Resident Evil: The Final Chapter as this role.
- Canon Foreigner: He was created for the film series as a replacement for canon character Dr. William Birkin, who had a sort of appearance in the first installment played by Jason Isaacs. His last name is even taken from Isaacs.
- The Chessmaster: The real Dr. Isaacs in Resident Evil: The Final Chapter is revealed to be the true mastermind behind the Apocalyptic Outbreak.
- Corrupt Corporate Executive: He's a member of Umbrella's senior leadership, and his original self was the co-founder.
- Cyborg: In The Final Chapter, The real Dr. Isaacs has computer-controlled "bio implants" to enhance his physical capabilities and reflexes. He's only slightly stronger than a Badass Normal and isn't quite at the superhuman level of Wesker or Plagas infected Rain, but does have the upper hand in a fight with Claire and a de-powered Alice. He's even able to keep going after taking a grenade to the chest, but the implants don't actually "heal" him and being stabbed in the chest by his clone is enough to finish him off.
- Deadpan Snarker: Has a very dry wit.
- Early-Bird Cameo: He actually appears at the tail end of the second movie.
- The Evil Genius: A brilliant scientist responsible for Alice's transformation, Matt's mutation into Nemesis, and the creation of the Red Queen.
- Evil Gloating: In the climax battle of Extinction, after overpowering Alice, Isaacs stops in front of her to give his villainous monologue about being the future, giving more than enough time to a recently awakened Alice clone to activate the laser grid and slice him in pieces.
- Expy: To Dr. William Birkin, with the real Dr. Isaacs being one to Oswell E. Spencer and the game version of Albert Wesker.
- Faux Affably Evil: Appears well-mannered and professional but is at the core is a sociopath.
- Greater-Scope Villain: The Final Chapter reveals that the real Dr. Isaacs was the ultimate mastermind behind the global T-Virus outbreak and the near-extinction of humanity, making him this for entire film series.
- Mad Scientist: Is willing to sacrifice not only his coworkers but even young children for the sake of testing the T-Virus and the monstrosities that develop from it.
- Schrödinger's Canon: His name appeared as "Dr. Sam Isaacs" in promotional materials and the novelizations of Apocalypse and Extinction. While Final Chapter gave his first name as Alexander, the fact that this is technically a different character (the previous one was his clone) leaves ambiguous if the first Isaacs was meant to be named Alexander too or instead was named Sam in order to differentiate him from the original.
- The Sociopath: An obvious Lack of Empathy for his victims, Faux Affably Evil and throws away his work just so he could toy with Alice.
- Smug Smiler: He hardly ever wipes that smarmy look off his face.
- The Starscream: Becomes this to Umbrella, after his mutation. A rare case of a character becoming his own Starscream.
- Suspiciously Similar Substitute: To the unnamed doctor from the first film who may or may not be William Birkin. The character of Isaacs was created to replace him when the actor couldn't make to the sequel.
- Adaptational Heroism: Albert Wesker in the games eventually attempted to cause humanity's extinction by way of virus and BOW spread. In a notable contrast, this version of Wesker, whilst by no means a good guy in any sense, is attempting to prevent it. Then in The Final Chapter it turns out it was all a trick and he was following Dr. Isaacs's orders to cause it all along.
- Adaptional Personality Change: Unlike his game counterpart, Wesker is fully loyal to Umbrella and never betrayed them at all.
- Adaptation Relationship Overhaul: In the games, Wesker debuted as a Raccoon City cop and boss to Jill and Chris who eventually revealed himself to be an agent of Umbrella. This doesn't happen in the films, where they don't seem to know him until much after the T-virus outbreak.
- Adaptional Wimp: In the games, it is impossible to defeat Wesker even in a two-on-one match. While he is still capable of beating Chris and Claire at the same time, he fails to defeat Alice and was overpowered easily. He also has more difficulty in controlling the virus within him and believes that consumiing Alice will solve this problem.
- Authority Equals Asskicking: He's the Chairman of Umbrella and by far their best fighter, thanks to his T-Virus enhancements.
- Bad Boss: In Afterlife, Wesker sees no problem in sacrificing hundreds of his own henchmen to kill the Alice clones. It gets worse after the helicopter crash: he has to eat humans to control his new power, which causes his crew to abandon him in the ship.
- Badass Longcoat: Much like his game counterpart, Wesker wears a black longcoat in Afterlife. Also his Sinister Shades.
- Big Bad: Appears to be this throughout the series, most prominently in Afterlife, then in The Final Chapter it turns out he's merely The Dragon to the real leader of Umbrella, the original Dr. Isaacs.
- Big Good: Models himself as humanity's in Retribution, but it all turns to be a ruse.
- Cold Ham: Chews plenty of scenery in his scenes, but never lifts his voice.
- Cool Shades: Wouldn't be Wesker without them.
- Corrupt Corporate Executive: Is the Chairman of Umbrella in the films' continuity, though The Final Chapter reveals that the Umbrella founders Dr. Isaacs and Alicia Marcus outrank him.
- Death by Adaptation: In the novelization of Afterlife, he really dies in the explosion of the plane, as his return in Retribution's has him revealing the dead Wesker was actually a clone (though he might have been lying). This is a stark contrast to the films, where he survives everything they throw at him and never needs to be cloned.
- Demoted to Dragon: In The Final Chapter, compared to the original Dr. Alexander Isaacs, an Expy of Oswell E. Spencer.
- Dropped a Bridge on Him: Wesker, who's been built up as the Big Bad of the series, ends up being upstaged by Marcus in The Final Chapter, incapacitated by an extremely mundane injury he should have been able to easily avoid with his powers, which he never even uses for some reason, and gets killed off in an extremely anticlimactic manner, without even a fight scene. The novelization of The Final Chapter attempts to explain this discrepancy, among other things, aside from implying he did not die.
- Enemy Mine: Force to team with Alice as Washington, D.C is the last fortress of humanity left standing against the Red Queen and her monster army.
- Forgot About His Powers: Played straight in The Final Chapter itself (see Dropped a Bridge on Him), but Subverted Trope according to the novelization, wherein it is stated that Wesker doesn't use his powers after being crushed by the bulkhead by the Red Queen because his enhancements are unstable and trying to use them after losing so much genetic material (blood) would kill him. In fact, crushing him to immobilize him until he bleeds out is pretty much the only way to kill him, as he's shown to be able to regenerate lost body parts up to and including having his head blown off (he says he's distributed his brain throughout his entire body so he doesn't have a weak point). And yet, the epilogue shows he is actually still alive and waiting to recover.
- The Heavy: He is the leader of Umbrella's forces when his boss Dr. Isaacs is not around.
- I'm a Humanitarian: Forced to do this due to injecting the T-Virus in himself and needs new DNA to stay in control. Otherwise he'll become a mindless monster.
- Lamprey Mouth: In Afterlife, due to his T-Virus enhancements destabilizing his DNA, he manifests a Plagas-like mouth for consuming fresh human genetic material to stabilize himself.
- Lightning Bruiser: Incredibly strong, resilient and capable of Flash Step tricks.
- Made of Iron: Wesker manages to recover and casually walk away from damage that action movie convention dictates should be enough to kill any other supervillain, right up to having a good chunk of his head blown off and having his corpse riddled with bullets by the heroes just to make absolutely sure.
- Nigh Invulnerable: Thanks to his Healing Factor, he can recover from pretty much anything. In the ending of Afterlife he get hit by an giant explosion, which was not too long after being gunned down to death by Alice, Chris and Claire.
- Red Eyes, Take Warning: They're actually orange, but the meaning is the same.
- Spared by the Adaptation: In the The Final Chapter's novelization.
- The Stoic: His face is inexpressive to a ridiculous degree, although part of the effect is caused by his shades: he shows definitely more expression during the brief time he takes them off.
- Sunglasses at Night: Mostly to hide his monstrous form.
- Super Speed: He's got the same Flash Step ability as his game counterpart.
- Super Strength: And a similar level of enhanced strength as well.
- You Are Who You Eat: After being nearly killed in an explosion at the beginning of Afterlife, his T-Virus enhancements become unstable and he has to regularly eat people to stay human.
Supporting characters (by film of introduction)
Umbrella Special Forces Team
The leader of the commandos, tasked with disabling the Red Queen.
- Back from the Dead: For the fifth film via cloning.
- Bald, Black Leader Guy: He's bald, he's black, and he's the leader.
- Pet the Dog: When Alice says she doesn't want to remember what went on in the Hive, his response is a quiet "I don't blame you."
- The Leader: Of the Umbrella special forces team sent to investigate what happened in the Hive in the first film.
A tough commando without a care in the world... or is she?
- Action Girl: Not quite to Alice's level, but she certainly tries her best.
- Back from the Dead: Brought back as two clones for the fifth film.
- Jerk with a Heart of Gold: Despite being a hardass Umbrella commando, she ultimately proves to be quite reasonable.
- Hope Spot: She got infected but Alice had the cure and injected it into her. It seemed like it worked. But during the climax she turns and has to be put down.
- Those Two Guys: Her and J.D.
- Vasquez Always Dies: Seems Michelle Rodriguez always dies too.
- Zombie Infectee: Is the first among the squad to get infected. Throughout the film, she is bitten three times but miraculously manages to remain un-turned until the near end of the film where she succumbs to it.
- Disposable Pilot: Killed by a Licker while driving the escape tram.
- The Smart Guy: Seemingly the hacker of the group.
- Surprisingly Sudden Death: He survives being bitten and trapped by zombies and is given the cure. Then ends up killed by a Licker hitching a ride on the escape tram.
- Tempting Fate: "See how easy that was?"
- Those Two Guys: He and Rain.
- Zombie Infectee: Gets infected by a horde of zombies swarming the door he opened.
Olga Danilova / The Medic
- Off With Her Head: She's the first one killed by the Red Queen's lasers in the first film, and her head slides off.
- We Hardly Knew Ye: The first to die and the least important character.
- Big-Bad Ensemble: One of the main antagonists from the first film, alongside the Red Queen. Spence was the one who purposely caused the virus outbreak as a distraction for him to escape the Hive with the sample of T-Virus, which he would latter sell in the Black Market.
- Identity Amnesia: Because of the Red Queen's knockout gas. He's much nicer when he doesn't remember who he is.
- Karmic Death: Tried to escape on his own and got caught by a Licker.
- Shoot Out the Lock: He shot the lock on the room, trapping Alice, Matt and Rain inside.
- Villainous Legacy: His causing the T-Virus outbreak sets off the entire film series, as said outbreak spreads to Raccoon City and eventually the entire world. The guy pretty much caused the near extinction of humanity.
Matt Addison / Nemesis
- Action Survivor: He and Alice are the only ones who manage to escape The Hive alive.
- Badass Longcoat: As Nemesis, he wears a black longcoat.
- Canon Character All Along: His Matt Addison identity was created for the film and it was thought to be a Canon Foreigner until they revealed he was Nemesis's previous human existence.
- The Dragon: Nemesis, for Major Cain (and the whole Umbrella Corp.) in Apocalypse.
- HeelFace Turn: Regains his consciousness as Matt after Alice defeated him. He later helped Alice defeat a squadron of Umbrella security, along with two helicopters.
- Impaled with Extreme Prejudice: Alice impales him on a metal piece of a helicopter.
- More Dakka: Wields a rocket launcher and a minigun that has an ammunition of more than 4000.
- Rasputinian Death: According to Apocalypse's novelization, he was only incapacitated after being squashed by the helicopter; it was the nuclear strike that did him in.
- Redemption Equals Death: Gets crushed by the helicopter he shot in order to help Alice and the group.
- Split Personality: In the Apocalypse's novelization, Matt and Nemesis act as two separate personalities sharing one body; Nemesis being the dominant one, but both are fully aware. After his fight with Alice, Matt manages to regain control.
- Super Soldier: Matt was put under the program by Isaacs and Cain which gave him enhanced durability, and the strength to carry a minigun, a rocket launcher, and a large bulletproof suit. It also gave him a disfigured body and face, his speech being limited to grunts and howls, and can be remotely controlled by Umbrella operatives.
- The Mole: To Umbrella.
- Dead All Along: She was killed by the Red Queen's nerve gas alongside the others workers of The Hive in the beginning of the film. Matt encounter her, now as a undead.
- Canon Character All Along: Meta example. He is clearly based on Dr. William Birkin from the games, but whether he is actually meant to be Birkin or not is a mystery. He went uncredited at his sole film appearance, and info websites cannot just agree whether he is Birkin or a random "Unnamed Doctor". In any case, he ended up replaced by a direct Canon Foreigner, Dr. Alexander Isaacs, when the actor couldn't return for the sequel.
- Corrupt Corporate Executive: Like almost everybody in Umbrella.
- The Evil Genius: He took Matt away for him to be turned into Nemesis, and was apparently part of the team.
- Mad Scientist: One of many amoral scientists working for Umbrella.
- Minor Major Character: Seems to be a higher up in Umbrella, but he only appears in the first film and was replaced by Dr. Alexander Isaacs afterwards.
- Narrator All Along: He was the narrator of the first film before revealing himself as a character.
A cop who joins Alice and co to escape Raccoon City.
- Action Girl: In Apocalypse.
- Adaptational Wimp: A capable and competent character in the games, many of her heroic moments are instead given to Alice in Apocalypse, and she falls into useless panic when they are confronted by Nemesis, where Alice keeps a cool head.
- Blade on a Stick: Jill wields a lance during her fight with Alice in the fifth film.
- Brainwashed and Crazy: Revealed to be mind-controlled in Afterlife and stays that way through Retribution until Alice is able to pull the mind control device off of her.
- Death by Adaptation: She was killed in between the fifth and sixth film despite being still alive in the games.
- Empowered Badass Normal: Initially a fully human character with some badassery (even if not as much as in the games), her mind control device gives her increased strength and fighting awareness, allowing her to overpower Alice when brainwashed.
- FaceHeel Turn: She turns evil in the fourth and fifth films after being brainwashed by the Umbrella Corporation.
- Fair Cop: Quite beautiful, and a member of the RPD's elite response team, S.T.A.R.S.
- The Heavy: While the Red Queen serves as the Big Bad of Retribution, the leg work is carried out by Jill and her clone minions.
- HeelFace Turn: Once the device brainwashing her is removed by Alice.
- Male Gaze: When we first see her, we have some close ups on her breasts and legs.
- Ms. Fanservice: Having left the police force, Jill spends Apocalypse in her miniskirt and tube top from the third game, and the fifth game's Spy Catsuit in later films.
- Neck Lift: To Alice in Retribution.
- Race Lift: Actress Sienna Guillory is of Turkish-Jewish descent, while her video game counterpart is of Japanese and French ancestry.
- Screw This, I'm Outta Here!: Jill returns to the police station to announce her resignation, as she knows Raccoon City is beyond saving.
- Sexy Walk: Modeled after Jill's animations from the game.
- She's Got Legs: Lovingly showcased by her short skirt.
- Sole Survivor: The rest of the S.T.A.R.S. unit is wiped out by Nemesis.
- Spy Catsuit: In Afterlife and Retribuition, she wears a dark purple one while under Umbrella control. This is a nod to Resident Evil 5.
- Staking the Loved One: Forced to kill her teammate Peyton after he's killed by Nemesis and reanimated as a zombie.
- Turn in Your Badge: She's been suspended from the force prior to the beginning of Apocalypse.
- What Happened to the Mouse?: Isn't seen after Retribution. The novelization of the next film establishes she was killed by Wesker in the White House battle.
- What the Hell, Hero?: When investigating the school, in Apocalypse, Jill she decides the best course of action is to split up, give a gun to a civilian with no firearm training (and not even bother to instruct her how to use said firearm), and send the clearly unprepared woman on her way. Terri, of course, dies horribly and immediately.
A member of Umbrella's Biohazard Countermeasure Squad, sent in to contain the outbreak in Raccoon City.
- Adaptational Nationality: His nationality is never mentioned beyond his traditional South American billing, but it's notable that his surname in the games is written as Oliveira (a Portuguese surname, implying he might be Brazilian), while the films spell it as Olivera (its Spanish form, meaning he might come from a Spanish-speaking Latin country instead). The novelizations also establish he's of Israeli descent, just like his actor.
- Death by Adaptation: Still alive in the games, dies in the third movie.
- Dying Moment of Awesome: Detialed in the Heroic Sacrifice entry below.
- Face Death with Dignity: His death? A heroic sacrifice where he blows up a van and takes out a horde of zombies. His reaction just before the explosion? He takes a small piece of weed he found lying in the van and smokes it.
- Fake Nationality: If his name and video game counterpart is anything to go by, Oliveira is still half-Latino, half-Native American, but is played by Israeli actor Oded Fehr.
- Heroic Sacrifice: He committed a suicide attack in a van to both create an opening in the of the fences surrounding Umbrella laboratory and to clear a pathway from zombies so Alice and the remnant of the convoy could enter it and take a helicopter to flee the infected zone.
- Knife Nut: In Apocalypse, he killed an infected, and an Umbrella bodyguard by throwing a knife at their heads.
- Last Kiss: Shares one with Alice before his Heroic Sacrifice, hinting at possible unresolved feelings between the two.
- Nice Guy: From his introduction, Carlos is shown to be very concerned with helping civilians, setting him apart from his employers and most of his teammates.
- Perma-Stubble: Across three movies, never seems to find a razor.
- Race Lift: Latin-American in the games, played by an Israeli actor in the movies.
- Smoking Is Cool: His last act before a Heroic Sacrifice is to light up a joint.
- Token Good Teammate: One of the few UBCS members who isn't a sociopathic asshole.
- You Don't Look Like You: Oded Fehr is substantially different from the more round-faced Carlos from the games. Ironically, he looks somewhat more like Chris's rendition in the first RE.
- Zombie Infectee: In Apocalypse, he mentioned that he was bitten 3 hours ago but kept it a secret from LJ when they were exploring the school. Luckily, Alice quickly gave him the anti-virus. In Extinction, he gets infected again but this time, he decided to perform a Heroic Sacrifice.
- Eaten Alive: Via zombie children.
- Survival Mantra: In a deleted scene, when Terri states that she has never shot a gun before, Jill says "There's nothing to it. Point, pull, repeat. Try to hit 'em in the head." Terri then walks down the hallway whispering to herself, "Point, pull, repeat... point, pull, repeat."
- Too Dumb to Live: Oh yeah, go off on your own in a zombie infested building. It'll surely end well.
- Wouldn't Hurt a Child: In the novelization of Apocalypse, after being surrounded by zombified children, Terri cannot bring herself to shoot them because they're still kids.
Lloyd Jefferson "L.J." Wayne
- Hypocrite: In Apocalypse he criticizes Carlos for not telling him when he got bit, but in Extinction he keeps it secret when he gets bit himself, and ends up biting Carlos after he turns.
- Took a Level in Badass: Was able to survive a zombie apocalypse for five years.
- Zombie Infectee: He gets bitten early in the third film and hides it, which ends up getting Carlos killed.
- Black Dude Dies First: The first significant casualty of Apocalypse.
- Zombie Infectee: Is bitten during the film. Peyton revives as zombie even after being gunned down by Nemesis.
- Adaptational Heroism: He was the main human villain in Resident Evil 3: Nemesis. Here, he's one of the more honorable Umbrella operatives.
- Oh, Crap!: "Oh shit."
- You Don't Look Like You: Most of the game characters sport some resemblance their original. The man doesn't look anything like him in the game.
- We Hardly Knew Ye: Barely in the film past his introduction before being killed off.
- Canon Foreigner: Created for the films.
- Expy: Of Sherry Birkin from Resident Evil 2, both being the daughter of the creator of a virus that is causing havok in Raccoon City and wanted by Umbrella Corporation.
- Living MacGuffin: The plot of Apocalypse is basically finding her, so that her father will send an helicopter to take the heroes out of the city before Umbrella launches a nuke.
- Psychic Powers: Like Alice, her bond with the T-virus seems to have given her those. She displays some limited Telepathy to contact with Alice at the epilogue of Apocalypse.
- What Happened to the Mouse?: Angela dissapears after the events of Apocalypse and is not mentioned again. The novelization of the next film (based on an idea from the script that got cut off) states she was murdered by a Umbrella-controlled Alice.
Dr. Charles Ashford
- Canon Foreigner: Not completely; he was created for the films, though taking a lot from Edward Ashford.
- The Dog Bites Back: After Major Cain guns him down where he stands, or rather sits in his wheelchair, he's the first zombie to kill the major.
- Expy: A modern-day one from Dr. Edward Ashford, an ancient pioneer of the T-virus from the games.
- Genius Cripple: Created the T-Virus and is confined to a wheelchair.
- Good Parents: Absolutely refuses to leave Raccoon City without his daughter and in fact injected her with a diluted version of the T-Virus so that she can walk.
- Mission Control: Acts as this to Alice, Carlos and Jill.
- Shout-Out: His surname is one to the Ashford family from the games.
- Token Good Teammate: Of Umbrella.
- Well-Intentioned Extremist: He only created the T-virus to cure his daughter Angela of a degenerative disease.
Major Timothy Cain
- Bad Boss: He executes Dr. Ashford despite the man being one of Umbrella's highest ranking members, solely to prove to his captives that he's willing to kill anyone.
- Better to Die than Be Killed: When he's surrounded by zombies, he tries to shoot himself in the head. Unfortunately, his gun is empty.
- Big Bad: The main antagonist of Apocalypse, being responsible for the sealed off Raccoon City and the activation of the "Nemesis Project", used to kill off the members of S.T.A.R.S.
- Karmic Death: When left alone and surrounded by zombies, Cain attempt suicide, but his gun is out of ammo and he gets eaten alive. Among the zombies includes Dr. Ashford who Cain kills earlier and he gets the first bite.
- The Man Behind the Man: The man behind Nemesis.
- Straw Nihilist: Due to his experiences in the Gulf War, he is firmly convinced that "life is cheap."
- Dirty Coward: A deleted scene has him abandoning co-worker Marla Maples to be Devoured by the Horde. Averted in the finished film, where he helps Peyton and Terri bar the church doors against some zombies.
- Hand Cannon: He's armed with a huge Magnum.
- Killed Offscreen: We see the Licker lunge at him, but then it cuts away abruptly.
- Peek-a-Boo Corpse: The Licker drops his mangled body down on top of Jill when she goes looking for him.
- Red Shirt: His only purpose in the story is to get killed.
- Screw This, I'm Outta Here!: Runs away when the Lickers show up. Unfortunately, he runs straight into danger and ends up on the receiving end of a slithery Licker tongue.
- We Hardly Knew Ye: He dies pretty much as soon as he's introduced.
- And Then John Was a Zombie: He turns abruptly once he, Carlos and Nicholai get to the hospital.
- Doomed Hurt Guy: Wounded and infected with the T-Virus, he gets dragged around by his friends in the hopes that they can rendezvous with their fellow U.B.C.S. and get him the cure. However, he ends up turning into a zombie and needing to be killed.
- Expy: Of Murphy Seeker from Resident Evil 3: Nemesis.
- Red Shirt: Of the three main U.B.C.S. characters, he's the most obviously doomed one.
- Russian Guy Suffers Most: He's a Russian U.B.C.S. member and really gets put through the wringer.
- Zombie Infectee: Spends most of his screentime slowly turning into a zombie.
The leader of a convoy of survivors roaming post-apocalyptic America.
- Action Girl: Especially in Afterlife, during her fight with the Executioner.
- Brainwashed and Crazy: An Umbrella mind control device renders her feral and amnesiac in Afterlife.
- Cool Shades: In Extinction.
- Deadpan Snarker: Like most everybody still alive at this point.
- Fiery Redhead: She has red hair and a bit of a hair trigger.
- Fire-Forged Friends: With Alice. By The Final Chapter, they've weathered several crises together, and trust one another above all.
- Laser-Guided Amnesia: Via a mind control device. It takes her awhile to recover from it.
- What Happened to the Mouse?: No mention of her in Retribution. Word of God says she's been re-captured by Umbrella and "her whereabouts are unknown"]. Averted in The Final Chapter, where she's the only major character from the games to return for the Series Finale, while the fates of Chris, Jill, Leon, and Ada are left hanging.
- Only Known by Their Nickname: She was found by Claire's convoy hiding out in a K-Mart and kept going by the name afterward, as she didn't like her real name.
- What Happened to the Mouse?: Isn't mentioned in Retribution. Word of God says she's been re-captured by Umbrella and "her whereabouts are unknown".
- Black Girl Dies First: Betty is the first named member of the convoy to die in the film.
- Eaten Alive: By zombie crows.
- Official Couple: With L.J.
- Eaten Alive: By Dr. Issacs enhanced zombies.
- Friendly Sniper: Chase seems to get along with the others members of the Convoy.
- Heroic Sacrifice: Holds off as many zombies as he can to give Clarie time to escape.
- Revolvers Are Just Better: As befitting his overall "Cowboy" appearance, he carries a revolver and promptly uses it to blow an approaching zombie's head off. Subverted in that it does him little good in the long run.
Capt. Alexander Slater
- Evil Brit: His accent is British, and he's the right hand man of Isaccs until he betrays him, which only leads to his death.
- Eye Scream: Part of the way Isaacs kills him is by using two of his tentacles to gouge his eyes out after he mutates. The third tentacle going into his mouth.
- Jerkass: Especially when he betrays Isaacs, not that Isaacs was much better.
- Only Sane Man: Is freaked out when he sees that Isaacs was over-using the anti-virus.
- The Starscream: To Isaacs.
- Actor Allusion: Is introduced being locked up in a prison cell. Then you remember what show his actor played on.
- Remember the New Guy?: Wesker seems to have a past with him, despite the fact that in this continuity Wesker is the chairman of Umbrella rather than the captain of S.T.A.R.S, and the movie Chris might not even have been part of S.T.A.R.S. at all.
- What Happened to the Mouse?: Isn't mentioned at all in Retribution or The Final Chapter. Word of God says he was captured by Umbrella and "his whereabouts are unknown".
- Action Survivor: Implied to be this before joining the Los Angeles building survivors.
- Bald, Black Leader Guy: Some stranded survivors in a building complex were able to survive while besieged by undead because of his decisive leadership. He's also bald to a T as Michael Jordan.
- The Big Guy: Right off the bat, he's seen dragging Kim's heavy trolley for him along with his own load, and later on he's able to stop a plane from tipping over the roof. A plane!
- Black Guy Dies First: Notably averted in both movies he appears in. In Afterlife he is shown captured by a zombies mouth and implied to have been killed only to show up later escaping from Los Angeles's sewer system as he runs out to a wasteland and kills two zombies chasing him, even witnessing the Umbrella soldiers on the march in their mission to capture Alice. In Retribution, he is the last person on the good guy's side to die after a prolonged intense battle against a superhuman clone.
- Celebrity Survivor: He was a basketball player before the zombie apocalypse.
- Killed Off for Real: In Retribution when Bad Clone Rain hits his heart, causing it to stop.
- Et Tu, Brute?: Ends up being backstabbed by a frustrated Bennett.
- Nice Guy: The first one of the Los Angeles survivors to befriend Alice.
- Surprisingly Sudden Death: Backstabbed by Bennett, who decides to abandon the others and escape using Alice's plane.
- Celebrity Survivor: He was a movie producer before the zombie apocalypse, and is so arrogant that he thinks this means he has privileges.
- Establishing Character Moment: When Angel spots a plane approaching, Bennett becomes relieved, thinking that Arcadia finally have come to rescue them. Angel asks the others for help in slowing down the plane during its landing, but Benneth just watches the others do the work. When Alice tells them that she isn't from Arcadia, Benneth goes away, dissapointed.
- Famous Last Words: Right before Wesker eats him alive."Oh God, I just want to go home. Aaaah!"
- Karmic Death: Just like he killed Angel and abandoned the other survivors and escaped by himself, Alice and co. leave him locked up with a hungry Wesker who revives and kills him.
- The Load: He is said to be too arrogant to do anything.
- The Renfield: He ends up as Wesker's servant in exchange for his life. He looks almost undead at this point (though still seems to be his normal asshole self), and it's not clear whether Wesker made him a Majini or partially drained him to stabilize himself.
- Take That!: Probably to the real life producers who infamously meddled in the production of Apocalypse.
- You Have Outlived Your Usefulness: Wesker kills him to absorb new DNA and remain in control.
- Establishing Character Moment: When Angel spots a plane approaching, Kim asks him what to do. Angel tell him to help slowing down the plane during the landing, but the materials are too heavy and Luther has to do it for him.
- Guilt-Ridden Accomplice: May have been the reason why he couldn't bring himself to escape with Bennett.
- The Load: Even more than Bennett.
- Dirty Old Man: Attempts to spy on Alice when she takes a bath. It ends up costing his life, but not because of Alice.
- Establishing Character Moment: Alice meets him guarding Chris's cell while reading an adult magazine.
- Celebrity Survivor: She was an actress before the zombie apocalypse.
- Nice Girl: Easily the nicest Los Angeles survivor, alongside Angel and Luther.
- Punny Name: She is a good swimmer.
- Action Girl: Just like in the games.
- Adaptational Badass: In the film, her duel with Alice ends with the latter holding a knife to her throat after immobilizing Ada's gun hand. In the novelization, however, the duel ends instead in a Mexican Standoff, as Alice fails at catching her hand and it allows Ada to hold her at gunpoint; it is pretty much the only time in the entire novelization-verse that Alice doesn't win a hand-to-hand scuffle against a non-enhanced enemy.
- Badass in Distress: After being captured off-screen by a brainwashed Jill Valentine.
- Badass Normal: Goes toe to toe with Alice in their introduction and is the only fully human, non-enhanced character who does so.
- * Death by Adaptation: She died in between the fifth and sixth film despite still alive in the games.
- Exposed to the Elements: Justified because Umbrella Prime's vaults are kept at room temperature, but a light Chinese dress is still a weird outfit choice to wear to a mission in Siberia.
- Grappling-Hook Pistol: Uses one in some scenes, just like her videogame counterpart. She give it to Alice after they are ambushed by Umbrella soldiers in the Suburban setting.
- Lady in Red: Wears a red Qipao.
- Nominal Hero: She's introduced in the story as Wesker's loyal field agent and ony acts on his behalf, meaning that she might well be just as amoral as he is.
- Sexy Spectacles: Her tactical glasses.
- Never Found the Body: Alice mentions that Ada was unable to escape and assumed her to be dead in the explosion, but Leon quickly disagrees.Alice: She didn't make it.Leon: You saw her die?Alice: NoLeon: She always has a plan.
- What Happened to the Mouse?: Not seen after Retribution. The novelization of the next film establishes she was killed in the White House battle.
Leon S. Kennedy
- Action Survivor: Survives the events of Resident Evil: Retribution.
- Adaptation Origin Connection: Promotional info for Resident Evil: Apocalypse states Leon was Jill's partner in the Raccoon City Police Department and was thought dead after an incident before the events of the film. In the games, he was certainly in the RCCD, but he was not Jill's partner and has never interacted with her in the entire franchise. The canonicity of this promotional info is debatable, though; Retribution neither confirms nor rebuts it, as their possible interactions outside from fighting in opposite sides are not fleshed out (note that the novelization does rebut it, but it also contains some changes in the plot).
- Adaptation Relationship Overhaul: This version of Leon is officially pals with Barry, while in the games they have never met.
- Death by Adaptation: He died in between the fifth and sixth film despite still alive in the games.
- The Leader: Of the resistence force assembled by Wesker to rescue Alice from Umbrella Prime.
- Schrödinger's Canon: According to a promotional newspaper for Apocalypse, Leon died before the events of this film in an incident involving Umbrella creatures which left Jill with PTSD. However, Kennedy later appears alive and well in Retribution. The two pieces are not incompatible, as he might have been simply declared MIA and secretly captured by Umbrella, but this has never been officially addressed.
- ¡Three Amigos!: Forms this with Luther and Barry in Retribution.
- What Happened to the Mouse?: Last seen on the White House preparing for a last stand. Not mentioned in Final Chapter. According to the novelization, he died right there.
- Blood Knight: His Pre-Mortem One-Liner to Leon shows how much he likes gunfights.I'm kind of enjoying myself!
- Death by Adaptation: Still alive in the games, dies in the movie.
- Heroic Sacrifice: Barry volunteers to hold the Umbrella commandos off so the others can get the elevator out.
- Not Quite Dead: Shot repeatedly but manages to get back up and blow away one of the mercenaries, only to get gunned down instantly afterward.
- Chainsaw Good: After being surrounded by the Las Plagas army and driven into a corner store at the Moscow seeting, Rosato is killed by an chainsaw-wielding zombie.
- Shout-Out: To the late Tony Rosato, the voice actor behind Dario Rosso and Nemesis in the third Resident Evil game.
- Adaptational Heroism: Like Nicholai from Apocalypse, he was one of the game's Big Bads (in this case, the main villain of Umbrella Chronicles). Unlike Nicholai, however, Sergei's name and USSR background are the only things in common with his videogame version.
- Adaptational Wimp: The game version of Sergei was the template from the Tyrants and capable of going toe-to-toe with Wesker himself. His film version is a regular human soldier.
- Off with His Head!: Get's pulled onto a roof by a Licker and decapitated.
- The Smart Guy: Used to be an technician working for Umbrella, explaining his ability to infiltrate the corporations systems without issue.
Racoon City survivors
- Deadly Rotary Fan: Wesker uses one of these to kill the group. This results in Abigail getting shredded to Ludicrous Gibs.
- Flipping the Bird: Does this to Wesker, through a camera. He doesn't take it well.
- Character Death: Christian is killed by mutated guard dogs, released by Wesker.
- Devoured by the Horde: Devoured by Dr. Isaacs zombies during the battle on Racoon City.
- Eaten Alive: By the BOW.
- Expy: In a surprising case of Shown Their Work, he's essentially Neil Fisher from Revelations 2. He even looks exactly like Neil, and given that we're never given his real name, he could very well be Neil.
- The Mole: To Umbrella Corporation.
- Out-Gambitted: Alice founds out that he was the traitor because he is still alive and outsmarted him by giving him a weapon without ammo.
Dr. James Marcus
- Adaptional Heroism: In the games, Marcus is a sadistic Mad Scientist who performs countless of horrific experiments on his trainees with the Progenitor and T-Viruses. After he was resurrected by the Queen Leech, he leaks the virus into every Umbrella Facility within the mountains and plans to spread it further into the world. Here, Marcus is actually a well-mannered scientist who created the T-Virus to treat his daughter and was against using it as a bio-weapon.
- Honest Corporate Executive: He was only ever interested in the medical potential of the T-Virus, and tried to halt its use when the more gruesome side effects became clear.
- Luke, I Am Your Father: Since Alice is a clone of his daughter Alicia Marcus, he can be considered her father.
- Our Founder: Of Umbrella Corporation.
- Posthumous Character: He was killed by Wesker under Isaacs' orders before the events of the first film.
- Suspiciously Similar Substitute: To Charles Ashford of Apocalypse, who was previously credited as the creator of the T-Virus.
- Well-Intentioned Extremist: Like Dr. Ashford, he created the T-virus to cure his daughter Alicia of premature aging.
Alicia Marcus/ Original Alice
- Face Death with Dignity: Alicia closes her eyes as the bomb on Wesker goes off and destroys the entire Hive.
- Slept Through the Apocalypse: She was sleeping in a cyrogenic capsule.
- Walking Spoiler: Can't say much about her without spoiling that Alice is her clone and that the Red Queen hologram was modeled after her.
- Younger Than They Look: Alicia suffers from progeria, causing her to appear as a very old woman.
- Conspicuous CGI: Fairly obvious in the first few films.
- Degraded Boss: He returns in the sequels, but in higher numbers and as Elite Mooks.
- Final Boss: Of the first film.
- Overly Long Tongue: Which can wrap around people's necks and pull them in.
- Took a Level in Badass: The single licker in Retribution is a much more significant threat than the pack of them in Apocalypse, although he does look substantially bigger in that the former film.
- Decoy Protagonist: Alice seemingly dies in the beginning of Resident Evil: Extinction. Then it is revealed that it's just a clone. It happens again in Resident Evil: Retribution, this time Alice is a suburban mother married to a Carlos Olivera clone.
- Hive Mind: Not directly stated, but strongly implied, at least to some degree, given that the original had telepathy and the rest are incredibly coordinate during their attack on Umbrella. Posterior deleted scenes and novelizations show Alice also inherites some memories from them.
- Me's a Crowd: At the end of the third film, Alice teams up with a large number of clones of herself, with the intention of going after Umbrella.
- Psychic Powers: Just like the original.
- Story-Breaker Power: The main reason they are disposed in the beginning of Afterfile.
- Designer Babies: Possibly, for experiment purposes. While it is clear that Becky's "mother" didn't physically give birth to her (they are all clones created in a factory), it is unknown if the Becky clones were created by mixing Alice and Carlos's DNA as in a real child or are instead created from a completely different person and simply put to play their daughter.
- Infant Immortality: You gotta wonder why she wasn't killed by the Licker.
'Good' Rain Ocampo
- Doesn't Like Guns: At first, until Alice shows her how to use them.
- Neck Snap: Due to being knocked into a wall by a Licker.
'Bad' Rain Ocampo
- The Brute: She gets obvious pleasure from beating people to death and shows absolutely no subtly and little technique in her fighting style.
- Curb-Stomp Battle: Delivered many against the heroes at the climax of "Retribution", killing at least one of them in the process. So much so that the only way to kill her was to shoot the ice underneath her and let the zombies have her.
- Dark Action Girl: Even moreso after she injects a Las Plagas into her.
- Empowered Badass Normal: Thanks to the Las Plagas parasite, which makes her stronger and Nigh Invulnerable.
- Evil Twin: A clone of Rain created to serve Umbrella.
- Fate Worse than Death: Dragged underwater by zombies and nommed on. The novelization of the film points out how the Las Plagas made her practically invulnerable, so she's not dying anytime soon.
- Final Boss: Of Retribution.
'Bad' James 'One' Shade
- Black Dude Dies First: the first of Umbrella 'bad clones' to die.
- Evil Twin: He's a clone of the original One made to serve Umbrella.
'Good' Carlos Olivera
- Face-Revealing Turn: After the clone Alice returns to her home, only to find he's become a Las Plagas zombie and kill her.
- Heroic Sacrifice: Dies to save the clone Alice and their daughter Becky. Unfortunately, he also ends up killing Clone!Alice.
'Bad' Carlos Olivera
- Evil Twin: A clone of Carlos made to serve Umbrella.
Clone Isaacs (2)
- Bad Boss: Murders his own lackeys.
- Cloning Blues: After smugly dissecting the psychology of the Isaacs clone from the third movie, he himself suffers a pretty epic Freak Out! on finding he's not the real deal either.
- Decoy Antagonist: He presents himself as (and believes he is) the real Isaacs. In reality, he's just another clone.
- Sinister Minister: While the original Isaacs only quotes the story of Noah's Ark as inspiration for his apocalyptic plans, this version seems to be suffering from some pretty severe religious mania, to the point of converting his APC into a sort of mobile cult compound where he keeps some indoctrinated prisoners.