Yokoi Rumi from My Neighbor Seki is a textbook example. Humans, animal, toys and shogi pieces will all get a piece of her giant kindness.
The Touden siblings, Laios and Falin, from Delicious in Dungeon. Both are the most friendly characters in the series by a long shot, as well as being very selfless and helpful. And any ulterior motives Laios might have don't go past wanting to eat something unusual.
Six Half has Akio Kikukawa. He is just nice and an absolute sweetheart. He always puts his family ahead of himself, is willing and ready to listen to them at any point of the day or night and encourages them to do things they want. Though there are implications that he can be not nice and his overall helpful personality to be part of a Stepford Smiler routine.
While she has her moments of temper from time to time, Maka Albarn from Soul Eater definitely qualifies. She'll generally be caring, compassionate, and kind in almost all situations (the only rare exception being when Soul is really frustrating her).
I Wish has Byeong-Hui Park. He is nice to a fault. He can't say no to a person that needs help, including giving them large amounts of money, because he can't get himself to turn someone down. Byeong-Hui also hates hurting people's feelings, so even if rejecting someone would be the better thing to do, he doesn't. Case in point, Lyu-Jin gave him chocolates for Valentine's Day once and Byeong-Hui ate them, despite being allergic to chocolate, just so she wouldn't be hurt. That's also why she's so scared of confessing her feelings to him.
Male leads who good are looking, popular, and nice guys are as common in Shoujo as their female counterparts are in Shonen; wish-fulfillment is large part of fiction after all.
Jinto from Crest of the Stars, almost to the point of self-effacement. He's also Iron Woobie and The Quisling at the same time and thus makes an interesting protagonist despite having a less flashy personality than some of the other characters.
Kenshiro, in spite of inheriting the head-popping Martial Art known as Fist of the North Star is a warm, gentle, sensitive and kind-hearted man who loves children and is not ashamedto cry. That said, cruelty to the innocent is the one thing he will not abide, and he can be an utterly terrifying enemy when he is pissed.
Kou from Cross Game and most Adachi protagonists show shades of this trope. You can actually see why girls would like them, as opposed to many shounen 'Nice Guys'.
Seiichirou Kitano from Angel Densetsu is a master of this. He actually seems incapable of wanting to hurt anyone, despite how he's treated.
Barakamon: Hiroshi is friendly and helpful, and act as a sort of big brother for the younger kids in the village. The teacher did'nt punish him for dying his hair blond to look less average, because he saw how polite he was and just forgot it.
Gintama: Tama is polite, gentle and helpful to everyone, and always listen to others problem . This is particularly notable in a serie where the majority of the cast, both male and female, often engage is Comedic Sociopathy.
Takato Matsuki from Digimon Tamers. The goggle-headed protagonist, he is not as hot-blooded as his predecessors or successors and is the normal one compared to his friends who have a myriad of issues. This, of course, gets deconstructed when it's revealed what happens when he is pushed too far. This also applies to his Digimon partner Guilmon.
Also Gabumon from the first season is easily the most gentle and polite of all the Digimon partners. He even took off his fur to warm Matt when Matt had a cold.
His nature is rather ungreedy; he appears calm and good at business, is tall, and tries to be philosophical (...) He often has a businesslike manner, but he jokes around with Portugal, China, and Hong Kong. He treats Taiwan like a Proper Lady.''
Belgium seems to be one. She's very sweet and works hard, especially when her brothers are concerned, but doesn't really stand out much.
Underneath his intimidating aura, Sweden is this: He's not only a Gentle Giant, but is very considerate, to the point that he personally resewed the clothing he gave to his friend Finlandnote They didn't fit him due to the height difference between them and was willing to live in a corner of their home to give Finland more space.
Along with Mai's brother Takumi, Kazuya Kurauchi is one of the genuinely nicer members of Mai-HiME's male cast, shown as a diligent worker and concerned with his girlfriend Akane's safety. He doesn't get much screen time, though, as he's the first one to get killed.
Hirasawa Yui of K-On! is the idealistic, innocent and warm heart that holds the "Afterschool Teatime" band together.
Jean Roque Raltique, from Nadia: The Secret of Blue Water, aside from being a nerd when it comes to technology and somewhat naive about social etiquette, is arguably the nicest character in the show. He's sweet, loyal, devoted, and willing to forgive others instantly. (The Grandis gang when they help him save Nadia, and the latter for her often misdirected occasional outbursts of rage at him.) Even so, Jean does go through a brief period of grief when he witnesses a friend of his die because of the technology he admires and later, learns about his dad's death. In one episode he also nearly strains his friendship with Hanson by trying to build a gyrocopter by himself (to impress Nadia), but soon acknowledges he can't do it alone. He also is quite brave; he puts his life in danger just to help the person he loves. And don't you dare try to hurt his friends in front of him.
Mikage of 07-Ghost. Complete with dying to motivate their hero buddy.
Bakuman。: They're everywhere. Which is natural, considering that it's a romantic comedy about writing manga. By the same people who brought you Death Note. The only real Jerk Asses in the series can be brought down to two: Ishizawa, who's had all of four appearances in this manga's over one hundred-chapter run, which, as of November 2012, is still going strong with it's third anime season, mind you, and one character who can't be named for spoiler reasons. It's also important to note exactly where the author choses to do this rather than creating a Jerkass character: the main editor had a lot of potential to be arrogant and dislikable, but they chose to make him a Reasonable Authority Figure instead; the main duo's rival, Teen Genius manga-writer Nizuma Eiji, also could have easily been an arrogant douchebag who flaunts his talent and power in the main character's faces, but he instead acknowledges their skills, thoroughly enjoys their work, often gives them helpful advice, shows up with a gift basket when The Hero is hospitalized, and wound up being voted the most popular character in a manga notable for its Loads and Loads of Characters.
Ayato from RahXephon is polite, friendly, easygoing and a decent human being. Amazingly, despite being the protagonist, he still manages to be a fascinating character.
Rock Lee. So much so, that he forgave Gaara for nearly crippling him for life and ending his career as a shinobi. Which is why Kishimoto said he needs no Character Development.
Chouji Akimichi is another example. He's a huge softie, getting emotional when he has to fight his reanimated sensei, and both his father and sensei state that his kind nature is his greatest quality.
Naruto Uzumaki. His kindness and Not So Different properties have redeemed psychopaths, unrepentant killers, as well as starting to affect the Kyuubi. After he saves Konoha from Pain, it appears the village finally sees these qualities. It becomes more prominent after the Time Skip. Having now friends and loved ones to take care of and vice versa, he was able to fully show off his caring side. Ever since he defeated and made peace with his Enemy Without, though, he's moved somewhat closer to being an All-Loving Hero, to boot.
Early Naruto was more a Jerk with a Heart of Gold - a foolhardy braggart who couldn't really understand how the people around him would feel about some of his behaviour, and sometimes made things worse because of his stupidity or boastfulness. Then again, he was viewed as an outcast for something he couldn't control and the isolation caused him to resent the village. He ended up choosing to become The Prankster as a means of getting attention, viewing it preferable than being looked at as not human. Once people accept for who he is and gains friends, he shows off that he really is a kind person, attributes that get expanded upon in filler.
Hinata Hyuga, Naruto's Living Emotional Crutchand future wife. This is easily her most definitive and persistent character trait during the entire series, more so than any other female in the series. How nice is she? She forgave Neji for almost killing her. Also, she doesn't put on airs, act prissy and/or as Shikamaru would say, isn't overly aggressive, demanding, or even scary (unless for a very valid reason instead of something petty or trivial). Finally, of all the Canon girls Naruto has ever met, she is the only one who is by far the most sweet-tempered, honest, open-minded and patient towards him, despite all his flaws that made all the other girls (particularly Tsunderes like Ino and especially Sakura) condescending, mood-swingy and judgmental towards him. This trait of Hinata's is one of the reasons why she is one of the biggestEnsemble Darkhorses in the whole series.
Iruka Umino, Naruto's Big Brother Mentor. His occasionally explosive temper aside, he's a very pleasant person to be around, being the first person to relate to Naruto on a personal level and never saw him as the Kyuubi unlike most villagers (notable because Iruka's parents were killed by the demon). In fact, his recognition of Naruto (along with others following) was what kept Naruto from falling into the same pits of despair as those like him did. Iruka's also an example of this trope done right—these very qualities are what make him an Ensemble Dark Horse, rather than the other way around (as the case would normally be).
Minato Namikaze (aka Fourth Hokage); even his future wife thought (at first) that he was a sissy because of his nice and polite demeanor (though others viewed him as a prodigy.) Like Father, Like SonandLike Parent, Like Spouse it would seem, considering that Naruto is his son and Hinata is Naruto's future wife.
The First Hokage, Hashirama Senju. He is perfectly friendly and courteous to Sasuke, who at the time is trying to destroy his village and all he ever worked for.
Tenma in Monster couldn't be nicer, unless you happened to have dumped him for politico-economic reasons. And, even then, he'll still risk his life to save yours. Even after all the stalking.
Nice Guy-dom is used as a cover for at least two characters in Darker Than Black: Hei and Nick. In both cases, it can be hard to tell how much of the act really is an act sometimes.
Allen Walker from D.Gray-Man is as nice as they come (outside of a game of poker), not to mention absolutely adorable and prone to trying to save everyone. He's got two or three girls in love with him, and one of them is the sworn enemy of his species.
Ash Ketchum. He's pretty much the nicest and sweetest character in that anime. Early on he had a more brash and immature personality but has mellowed out dramatically. Even flashbacks tend to portray him as the Nice Guy he became post-Character Development rather than the bratty Idiot Hero he was in Kanto.
Tracey, who replaced Brock for one half-season, is the embodiment of this trope. He's so polite and mild-mannered that many viewers write him off as bland and uninteresting. He Lampshades it in one side episode—after being pressured by Misty's oldest sister to clean the Gym, he's seen with a push broom and a sad expression, saying "Sometimes it doesn't pay to be the nice guy." (Just don't insult Professor Oak in front of him.)
Brock is no slouch, either. As Team Mom, he cooks and cares for his younger friends, provides help and encouragement with endless good-natured patience, and rarely loses his temper (when pretty girls aren't involved).
And then there's Luke who is one of the nicest of Ash's rivals/friends who doesn't insult him. His nice guy attitude is how he's able to put up with Bianca's quirks but even hehas his limits.
Out of Ash's female companions, while all of them are overall nice and kind-hearted (as long as you don't make them angry), Serena definitely takes the cake as the most sweet-tempered and gentle. It says a lot that she's the only one who doesn't immediately get annoyed at him when he does something rash, and the one time she did snap at him, it was because he wasn't being himself, and she immediately felt horrible for doing it.
We have Nao from the Liar Game, perhaps the most pure and honest character in the whole series. In fact, her reason for continuing with the game is to save everyone else in the game, including the ones who had deceived and gloated cruelly in her face.
Master Keaton: Taichii Hiraga Keaton is an all around nice guy who happens to be a former sergeant in the British Army and a veteran of the Falkland Wars. Now he's an adjunct archaeology professor who also works as an investigator for Lloyds of London. Keaton is free from all of the arrogance and eccentricities that are normally associated with very smart people. Frankly, Keaton tends to meet all sorts of eccentrics in his line of work. Although he can kick ass if he wanted to, he prefers to use his intellect. So he's also a pacifist.
Roy Berlinetta was one of these when he was alive. The very fist thing he was shown doing was buying hot treats for a group of orphans who were shoveling snow. And he doted on his adopted granddaughter Rinne (one of the aforementioned orphans).
Suzaku Kururugi starts off looking like this, but there are hints that something is up (such as his childhood best friend Lelouch musing on the fact that he used to be brash, hot-headed, and arrogant, making Lelouch wonder what could change someone so much in seven years). Later on, we learn that he's not quite as nice as he seemed in the first place, but horrifyingly broken.
Rivalz has shades of it, being a kindhearted slacker, and Gino Weinberg also has shades of it, as much as his duty as a Knight of Rounds allows.
Nunnally Lamperouge. She stays cheerful and kind through experiences that would leave most people shatteredand is fortunate enough to survive unlike the above girls, albeit after some serious breaking.
Yuji of Shakugan no Shana is an interesting variation of this whose niceness actually does get him girls. Ironically, instead of stifling romantic conflict, his niceness is also his greatest flaw, actually creating romantic conflict in the first half of Season 2, where he completely fails to realize that he can't give attention to every girl who's attracted to him without hurting the feelings of someone else, thus making him an accidental Master of the Mixed Message. And his friend Hayato does call him out on that. Eventually, he becomes less so through the course of the series and averts it after merging with the Snake of the Festival.
While Yuji is a Nice Guy in all of his media incarnations, the anime tends to gloss over or even omitt his ruthless streak (such as trying to kill Shana's mother figure Wilhelmina in retaliation for almsot killing him), which is much more prevalent in the light novels and anime. This has the unfortunate side effect of making Yuji's Face-Well-Intentioned Extremist Turn particularly jarring, rather than the natural evolution of his character.
Tea also falls for Nice Girl as she is always there for her friends, is extremely supportive, and has the kindest heart.
Judai Yuki in Yu-Gi-Oh! GX probably qualifies too. In one episode, he accepts a challenge from an Obelisk snob with a wager, where the winner gets to be Asuka's fiancee - despite the fact that he honestly doesn't know what a fiancee is. Somewhat deconstructed in the later seasons as the escalating risks and losing his friends take a toll on him. This culiminates in revealing he has a Super-Powered Evil Side that causes him no end of problems later, and once he recovers from it, not everyone is pleased with the fact that he seems to be much more serious from the experience.
On that note, Johan is probably a straighter example than Judai. He actually is a genuine nice guy, with no Super-Powered Evil Side trying to say take over, and selfless enough to pull a Heroic Sacrifice. Twice. And that for people he barely knows. Nice Guy ahoy.
Yusei is also a Nice Guy. Appearances and backstory aside, he is extremely heroic, friendly, kind-hearted, mature, caring, and selfless.
Yuma Tsukumo of Zexal, like the other protagonists before him will always choose his friends over himself.
Yuya Sakaki in ARCV continues this trope. He is a fun-loving, cheerful, and caring kid who all he wants to do is make the world smile as a "Entertainment Duelist".
Eiichirou of the manga Baby Steps. This is one of the reasons that Love Interest Natsu trusts him with her "big secret" (of wanting to someday become a professional tennis player) on the first day they met.
Eiichirou: Why did you let me in on your secret?
Natsu: ... because it's you. I mean, I know you wouldn't tell anyone.
Maison Ikkoku features Yusaku Godai, an honest example of this type of character. The series does not shy away from the flaws in these types of people — mediocrity/lack of ambition (or killer instinct), spinelessness (unwilling to hurt others' feelings), and being really indecisive. He also isn't entirely perfect, but he puts up with a lot of crap from others. And yet, his innate kindness and decency, along with his willingness to grow, more than compensate in the long run.
Ayumu Nishizawa is clearly a nice gal, paired with the fact that she's a normal person in a world where most of the rest of the cast are Ojous really makes Hata have to work to keep her relevant, and he does.
Hayate himself is a nice guy in general, despite being a Butt-Monkey. Isumi is this as well.
Akira Sakamoto of Princess Princess is such a Nice Guy that his excess niceness leaks out and forms an aura of soothing and healing vibes that refreshes everyone who comes into contact with him.
Not only is he trying to kick the habit, he runs a teashop that specifically caters to late teen-20 something female clientele; which is implied to be how he met Makiko. When Ayaka first sees him, she assumes he was behind the recent rash of vampire attacks, but it turned out Bosco was following Makiko at night to protect her from another vampire, who had recently reincarnated. Bosco and Makiko become an Official Couple by the end of the episode, after he helped save her.
Karino is an example, himself, as he often goes out of his way to prove to Ayaka that she can depend on him. Such as commissioning his extra assignments to Phantom Quest, as a personal favor to her, and by tailing suspects to help with their investigations, even though he's a bit of a screw up. Ayaka is flattered by the attention and she reciprocates... but she doesn't make it easy for him.
Hayato Kazami is a very polite boy for most of the time, and is willing to make friends with just about anyone.
Johji Ohtomo. In fact, it's this very trait that makes him friends with Hayato.
Despite being a quiet person (at least in the third OVA), Phill Fritz from SAGA and SIN is actually a pretty nice guy. It's just that Nagumo doesn't want him to have any contact with anyone outside his team.
Makoto Katagiri, if we check on minor characters. He is the most well-balanced staff member of the Aoi team.
Tsubasa Ohzora from Captain Tsubasa; when he's not on the field, that is. Taro Misaki, Gino Fernandez, Luciano Leo and Pepe are also nice guys as well.
Even when in the field, Tsubasa is pretty nice. In fact, he's been injured more than once while helping a teammate or a rival, like when he saved one of the Tachibana twins from falling head-on first to the ground (which would've almost surely killed him, or at least caused horrible damage) and got a dislocated shoulder for his trouble.
There aren't a lot of nice people in this series, let alone nice guys. So you can guess why Judeau has become the resident Ensemble Dark Horse because of his nice, laid-back personality.
Later, Sixth Ranger Roderick has revealed himself to be a nice guy, though not as popular as Judeau.
Jerome from the Retribution Arc can pretty much be considered a nice guy as well, as he is far more decent than some of the other guys around him.
GE - Good Ending features Utsumi Seiji, who is a pretty much an Unlucky Everydude who is sincerely nice to all his friends. Unfortunately, it tends to bite him in the ass as he sometimes ends up grabbing the Idiot Ball because he doesn't want to hurt anyone's feelings.
Kazuya Aoi from Freezing is the only one willing to look past Satellizer's shady background and discover that she's actually a really sweet girl, she just has some issues.
Dekisugi from Doraemon is this because his character is based on a perfect archetype of a Japanese schoolboy, in contrast of Nobita, who's a bit of a brat. In the movies, however, Nobita is upgraded into this trope, if not outright All-Loving Hero.
Dragon Ball sports a cast of various Nice Guys and Dogged Nice Guys among the heroes but Goku is one of the most famous in anime. So much so that nice guys of other Shōnen series have been based on him and his cheerful nature. No matter how grim a situation looks, Goku is always optimistic and smiling. He even dies smiling twice! He also easily forgives any villain that tried to kill him and his friends 5 minutes ago if they are willing to to stop being evil.
The only one who could pretty much outshine him in this department is his son Gohan, who lacks his father's Saiyan-related Blood Knight tendencies, though that doesn't mean he's a pushover: when he was a young boy he vaporized Cell with a one-handed Kamehameha while grinning like a madman.
Goku's other son, Goten, is closer to Goku in personality and is no less kind-hearted. He, like Gohan, also largely lacks Goku's Blood Knight tendancies. He's also quite a bit more naive/dumber than Gohan is.
Yugo Hachiken from Silver Spoon is one of these, willing to do anything for his new found friends at the Yezo Agricultural School, and is also rather friendly. His classmates are perfectly willing to use him for menial labor for this reason.
Despite being a moron, and sustaining physical abuse from his friends, Akihisa from Baka and Test: Summon the Beasts is generally a nice guy, and even HELPS the same friends who hurt him on a daily basis when they are in need.
A number of characters in Fruits Basket fit this. Tohru Honda is the most prominent, constantly putting the wellbeing of her friends and family before herself, often causing problems for herself in the process.
Momiji is consistently cheerful and friendly despite also being a member of the zodiac and has a horrific case of Parental Abandonment, he's still nice to everyone around him.
Madoka from Rinne No Lagrange pilots a mecha because her friend she just made, asked her to.
Both Belldandy and Keiichi of Ah! My Goddess are nice people, each being the Trope Codifier for Yamato Nadeshiko and Nice Guy respectively. In fact, their relationship exists because Keiichi was a fundamentally good enough person to attract a goddess's attention. Keiichi isn't a doormat; he's got a snarky personality and a backbone.
Nossori, Morimori and Sewashi from Mazinger Z, the three professors worked in the Photon Atomic Energy Research Institute by assisting Prof. Yumi and designing upgrades for Mazinger-Z and Aphrodite A were genuinely nice: they were kind, good-natured and very patient (you have to be to deal with so many hot-headed, impatient teenagers), even if they were somewhat goofy.
Sho Fukamachi in all three versions of Guyver — Guyver:Out of Control (1986),Guyver:Bio-Booster Armor (1989), and Guyver: The Bio Booster Armor (2005).
Tamaki in Ouran High School Host Club. His vices mostly come down to being an idiot, and a bit of a Drama Queen, but his all around niceness is the entire reason the club exists in the first place. He's the first person the twins met who actually cared which one was which, he calmly and quietly helped Haruhi when she was being bullied, and when he gave that bully what was coming to her, he still did so with politeness and grace. He's the top earner in the club, and as time goes on it becomes quite clear that it's because he's the only one there who is not acting to some degree or other and is in fact completely sincere. And that's not even going into how he deals with his Big, Screwed-Up Family.
Nanami Momozono from Kamisama Kiss is the nicest, friendliest person in the entire series and is incredibly optimistic even when things look to be at their worst.
Takehiko Yoichi from Haiyore! Nyarko-san wears the term "nice guy" like a glove. Being a minor character he doesn't get much screentime, but he's cool enough to pass off Nyarko's madcap antics as merely being "energetic", and at one point remarks "My best friend has a cute girlfriend, and that makes me as happy as if it had happened to me." About the biggest thing that's happened to him so far is temporarily having his body hijacked by a time-traveling alien extremist.
Hasta as well. Cute, sweet, cuddly and good-hearted young boy. So much so that of all the characters in Mahiro's harem that consist of Cthulhu Mythos, he's the only person who didn't receive the wrong end of the fork from Mahiro.
Karen is a very energetic and friendly half-British, half-Japanese girl and can get along with her fellow classmates to the point that they give her free snacks.
Alice is such a kindhearted sweetheart loli. She rarely hold any negative grudges and feelings towards anyone. In episode 7, Alice even help improve and teach Shinobu some English language skills (which Shinobu will later get a good grade in the following English test) and even help cheer Shinobu up when Alice finds out that Shinobu didn't do that well on her math test.
Shinobu herself is a relatively friendly girl despite being the resident ditz (particularly when both Alice and Shinobu first met in episode 1)
This trope is lampshaded on Youko in Karen's pie chart as "50% comedic retorts, 50% kind-hearted."
Marco, one of two resident Team Dads, is genial, friendly, and always the one attempting to keep the peace and raise morale among his fellow trainees.
Petra, who takes it upon herself to act as Eren's Cool Big Sis once the Survey Corps gets hold of him. The guidebook even gives her a rating of 10/10 in Kindness, and it shows. Neither she nor Marco survive.
Mihoko of Kazekoshi does all the chores for the mahjong club even though she, as a third-year and captain of the team, is exempt from them by virtue of seniority. When their coach threatens to punish players for minor mistakes that don't cost them the game, Mihoko stands up for them. She's also quite close to her teammate and friend Kana, the only one she addresses by her first name, helping her look after her sisters when their parents are away. Mihoko does all this so that the others can enjoy mahjong more, and while this helps low-ranking players like Bundou push themselves to improve, it also causes the others to worry about Mihoko, which is not what she wants.
Miho, who's kind and polite to her subordinates, the family servants, and many other people she's just met, even when said people are rude, hostile or threatening to her. In fact, the one time she gets angry with someone (her friend Emi, for saying that she hated Miho's sister Maho despite never having spoken to her), is treated as an O.O.C. Is Serious Business moment.
Koume Akeboshi, Miho's former teammate, whom she saved from drowning in the last tournament. She's grateful to Miho and worries about Miho after her departure from Black Forest, as Koume blames herself for causing Miho problems, rather than ostracizing her for sacrificing what might have been a tournament victory.
Seitenshi is a 16-year-old girl and a Reasonable Authority Figure ruler of Tokyo who happens to serve as a caring and compassionate motherly figure to many of the characters in the series. Heck, she's even pushing for civil rights for the cursed children.
TinaSprout was ordered by Ayn Rand to assassinate Seitenshi. Despite being an assassin ordered around by Ayn Rand, Tina happens to be a very friendly girl at heart who happen to befriend Rentaro when she first met him. In fact, her kind-hearted nature of her personality and her hesitation to kill someone makes Rentaro realize that Tina isn't an evil person at heart and isn't the kind of person who is willing to kill someone out of free will.
Maken-ki!: In addition t being a Kindhearted Cat Lover, Inaho is so compassionate, that when Takeru turned her down at the end of chapter 59, she accepted and asked Haruko to be good to him. But when Haruko fell into depression out of guilt, Inaho decided they should compete for him, to cheer her up — despite knowing she had no chance of winning.
Ranma ½: Though freakishly strong with a temper to match, Ryoga Hibiki really isn't all that bad once anyone gets to know him. It turns out he's such a softie that he's repeatedly stuck his neck out for Ranma, even if it means helping the girl he loves stay together with his sworn enemy.
ChihiroWatanuki from Yugami-kun ni wa Tomodachi ga Inai is a female example. While everyone ignores her classmate YuujiYugami, who sits next to her, because they find him a pain to deal with, Chihiro talks to him frequently despite his Brutal Honesty. Even when he offends her, Chihiro never holds a grudge and always thanks Yugami properly whenever he (sometimes unwittingly) helps her.
On the other hand, Yugami appears to be this when we first meet him, helping Chihiro find an empty slot for her bike in the school's bike lot. Unfortunately subverted for Chihiro when she meets Yugami again in class, as he is completelydifferent from the Nice Guy she thought she'd met just moments ago.
Usagi Tsukino (aka Sailor Moon), the main character of the show, is one of the friendliest and most compassionate heroes in anime and manga, once you get past her brattiness. During the R season, even though ChibiUsa causes the Senshi a lot of trouble and makes it clear that she has no respect for Usagi as a person or as a Senshi, Usagi constantly reaches out to her, and allows herself to be viciously attacked by Rubeus to keep ChibiUsa safe. She even tries to lift the spirits of an enemy (though she doesn't know it) who is actively going after Mamoru, her boyfriend and future husband!
Minako Aino (aka Sailor Venus), of who Usagi is an Expy of. While rough around the edges and rather Hot-Blooded, Minako will help everyone, even to her own detriment (a classic example comes from Codename: Sailor V, where she helped a mangaka who was late with her job without expecting to be paid even after finding out how hard it was, and when paid didn't put up much resistance when Artemis told her to give it back). This is balanced by how ruthless she is with those who threatens her friends or mission.
Ami Mizuno (aka Sailor Mercury) is generally the most peaceful and down-to-Earth, Senshi, though she isn't without her moments of Beware the Nice Ones ("Ami's First Love" being the best example).
Setsuna Meioh (aka Sailor Pluto) also counts, in contrast to the OuterSenshi, as she is the only Outer willing to cooperate with and help the Guardian Senshi, and is very caring and warm towards Chibiusa.
Among the lesser characters, Naru Osaka and Hikaru Sorano (who only appears in Codename: Sailor V) are almost as nice as Usagi, with Hikaru being so nice that Artemis once wished she was Sailor V.
"The Human Species lives to destroy other things, so your power is the most loving and gentle power in the world."
Takuto, the main character of Star Driver, is probably one of the nicest protagonists of any mecha anime ever. Friendly, helpful, respects anyone, up and including his enemies (except his Archnemesis Dad), and always finds something nice to say about someone. It shortly becomes a problem for him in the beginning of the second half of the story, though, when the Kiraboshi members manage to directly enter their Cybodies and Takuto has to find a way of destroying these mechas without actually harming their drivers.
In the same vein, Daichi, Hana, Teppei, and Akari from above's Spiritual SuccessorCaptain Earth are also some of the nicest protagonists in mecha anime history, especially Daichi and Hana. Must be the creators...
Eriko Hara from Venus Project: Climax. She gets along real well with pretty much everyone, she lives in an orphanage and befriends many of the kids living there, and in a flashback, she also shows remorse for Ruka Sovagasky when she loses in Eriko's debut match. She also has a sense of honor, when she shakes hands with her defeated opponent after the first round of the Formula Venus tournament in the second episode of the anime.
Aoi of Castle Town Dandelion is probably the nicest of the Sakurada siblings and the most considerate. This nature even has some more important implication, as it averts the potentially harmful effects of her Royalty SuperpowerAbsolute Order on the society despite the fact that she has been unwittingly using it for several years.
The first ending to Nurse Angel Ririka SOS outright states that Ririka is sweet. She has her rough traits and her enemies but she's overall nice. She is the Nurse Angel after all, and is the only one who can save the planet. She even undergoes a Heroic Sacrifice, though she apparently somehow lives.
Ririka is a kind girl.
She's a girl who's loved by everyone.
And when you're in a pinch, somehow she'll be there to give you a hand.
Yuzuru Otonashi is a guy who is willing to help others in need, hence the reason why he wishes to become a doctor. He is even willing to sacrifice his life in the train wreck and make himself an organ donor so that his remains can one day save someone else's life
Yusa Nishimori is a cheerful, kind, innocent, and friendly girl at heart. So much so that her kind and charming personality is one of the reasons why she is popular among her classmates (as well as being a famous Idol Singer). Her older sister who controls her body, however, istheopposite.
Kobayashi is one of the nicest, even-minded and friendliest people you'll find in an anime... when she's sober; when she's not, her voice goes a couple of decibels up and she gets aggressively talkative and pushy about maids in particular.
The main protagonist, Izuku Midoriya, a.k.a Deku. Despite being born without a Quirk, Deku happens to be a kind, selfess guy at heart who is willing to risk his life to protect others. In fact, his personality and his selflessness is one of the reasons he was caught attention from his favorite childhood hero, All-Might.
Ochako Uraraka is a friendly and charming girl who is most of the time seen with a smile in her face. Her primary motivation is to be a good heroine to earn money to support her parents, but that doesn't prevent her from helping people in need whenever she can.
Though she can be rather blunt, Momo Yaoyorozu is a sweet, compassionate person and she happily invites her classmates for a study session at her manor and gives them what are clearly very expensive sweets and tea during their stay, eagerly helping them pass the written portion of their exams.
Katarina used to be a spoiled brat until she hit her head one day and got back the memories of her past life as a normal schoolgirl. Unable to take her noble title so seriously anymore, she became super outgoing and friendly. And maybe she gave herself some brain damage in the process.
Furthermore, since Katarina knows that her spoiled behavior was going to lead to her death in one of several horrible ways, she keeps trying to avert it... but for the most part, her plans go nowhere, and instead she averts the death flags just by being a nice person. For example, her adoptive brother Keith was supposed to grow up bullied by Katarina, shunned by her mother (who mistakenly believed Keith to be her husband's illegitimate child), and starved for affection to the point that he became a shameless womanizer—and he murdered Katarina in several routes. In the new timeline, Katarina's initial attempts to be nice to him backfire, but her apology endears him to her, her mother ends up discussing the situation with her father and realizing that Keith isn't a bastard, and they grow up as a happy family.
While he does have a massive ego, Shirogane is fundamentally a very kind person, so much so that the very act of being cold to others causes him physical pain.
This applies to the entire cheer team, given how quickly the accept Ishigami as one of their own despite the rumors surrounding him and how out of place he is among them.
Rimuru Tempest from That Time I Got Reincarnated as a Slime is a very personable guy. Back when he was a human he threw himself in front of a guy's knife to save his co-worker and girlfriend's lives without hesitation, and in his slime reincarnation his excitable and kind nature have allowed him to befriend an imprisoned dragon, quell a war between goblins and wolves and make both sides become friends, and form friendships with some of the most powerful beings in the new world. It does help that he's got one of the most broken power and skill sets around, but he always tries to settle things peacefully and politely before using them, and that has earned him the respect, admiration, or love of all his subordinates. He didn't even try to form his own kingdom, it just kind of came together from all the people his attitude united.
Free!: There is a lot of nice guys in this show, but Makoto is the most popular so far. He's gentle, kind, Adorkable, Lovable Coward and Team Mom in one package. He's also universally friendly to anyone that doesn't provoke him and even if they do, he still tries to settle things as politely as he can.
Yamada himself starts out as a Jerk with a Heart of Gold, but has generally become a nice guy by the time of the second witch war. He still has a couple of Character Check moments here and there where he may act a bit unreasonable, but he's usually pleasant to hang around with, and he's a sufferer of Chronic Hero Syndrome.
Shiraishi is friendly and caring all the time (save the occasional Innocently Insensitive or snarky comment), if not always good at showing her emotions clearly.
Hotaru is usually cheerful, and he's polite and pleasant towards others.
When Otsuka's telepathy alter ego doesn't rear its ugly head, she's a fairly nice and gentle girl.
Sarushima is one of the friendliest characters in the series and generally the most sociable, well-adjusted and accommodating of the witches (at least before Shiraishi gets some Character Development).
Alex has a slightly mischievous side to him, but other than that, he's an easygoing Mellow Fellow who's always in a good mood and up for hanging out with others.
Konno was originally really nice (to the point of being a people-pleaser) and becomes it again (though much better at standing up for herself this time) after Yamada helps her.
Kotori is so helpful that she borders on being an Extreme Doormat. Nobody is forcing her but she still protects her whole class against the powers of other witches, which comes with of having to constantly read their minds, when they're not even her friends. She also has a friendly and polite, if a bit cautious, attitude beyond that.
Chikushi can seem a bit aloof, but she's reasonably friendly to those who get to know her, and her Masked JK project certainly shows that she cares about others.
Even though Seishuin looks a bit threatening when she appears, she's a nice person and gladly cooperates with the student council so that Yamada can copy her power.
Downplayed with Kikuchi. She's stoic, rushed and not one for casual small talk, but still very polite and cooperative.
Himekawa is gentle, compassionate and puts others' well-being and injuries well before her own.
Arisugawa is generally very good-natured, though she can also be slightly mischievous and is a skilled manipulator.
Date A Live has two prominent examples: Shido, who risks life and limb to protect the Spirits and give them the opportunity to have normal lives, and Yoshino, who would rather run away from a fight instead of harming another living creature.
The protagonist, Gon, is this, though with some Blue and Orange Morality mixed in due to his growing up largely outside of normal human society. He can't stand seeing innocent people get hurt, he believes every evil person is capable of being redeemed, and he will fight only when he has no other option. His kind, cheerful nature stands out in a world of Black and Gray Morality and, more than once, Gon has helped prevented someone he knows from Jumping Off the Slippery Slope into evil just by being nearby.
Goreinu is a player found in the lethal video game '"Greed Island''. Where other players are constantly trying to sabotage each other, steal from each other, or outright kill each other, Goreinu minds his own business while being savvy enough to avoid anything bad happening to him (though it helps that he has the power to teleport himself or his enemies away). Unlike most of the characters outside of Gon, Goreinu has no ulterior motives, no Dark and Troubled Past, no selfish desires, and no intent for any unnecessary harm to other people. The worst he's ever depicted is his reluctance to heal the injuries of a serial killer who almost killed him, and even then Goreinu ultimately heals him.