B.O.B.: Turns out, you don't need one.
(B.O.B. then forgets how to breathe)
In real life, having your brain physically removed from your body pretty much means you are dead. In comedy however the results can be a little different, leading to one of these outcomes (besides the realistic fatal one, obviously):
Walking Vegetable: In this case the body is in a drooling zombie like state, able to walk after a fashion but otherwise almost totally unaware of anything going on around them. Any speech will be monosyllabic. Can be done realistically, if some important parts of the brain remain but all the higher regions are gone.
Stupid but Aware: In this case the character has simply turned into The Ditz - they are much stupider than usual but able to talk properly, walk around without bumping into things and so on. Probably the least common category.
No Change: This is most likely to happen to a character who is already The Ditz. Brain falls out, is stolen or whatever and the de-brained character acts exactly the same (and may not even notice their brain is gone.) Sometimes the brain will be far smaller than normal to begin with.
No brain to lose: A slight variation on the above; it turns out the character doesn't have a brain in the first place!
See also In One Ear, Out the Other which is often how the absence of a brain is revealed.
- Furanpaa, the zombie receptionist from Interspecies Reviewers removes her brain to pass the time between guests without succumbing to boredom.
- In Nodwick, people who get their brains stolen (usually due to a nearby Mind Flayer) end up like this. In one instance, Piffany kept Yeagar's body going by giving him a 'replacement brain' (she put a butterfly inside his skull cavity).
- Rare "serious" example: the infamous Star Trek: The Original Series episode "Spock's Brain". Spock's brain is stolen by aliens who use it as a computer to run their planet's infrastructure. For some reason, his autonomic functions still work, but he is completely unconscious. Kirk has to get the brain back quickly, because Spock's Vulcan physiology is especially dependent on that tremendous brain. (While a brain-dead human could be kept "alive" easily for quite some time.) So that they can restore the brain quickly when they find it, McCoy rigs up a device that fits on Spock's head and allows his lifeless body to walk around, manipulated by a remote control. With three buttons. SPOCK has made a song called "Mr. Spock's Brain", based on the above episode.
- In a Wizards of Waverly Place episode Alex and Harper switch brains, and while trying to get back into each other's bodies, both brains end up in Alex's head. Harper's brainless body wanders around with a stupid grin on her face spouting random words, though she seems to be slightly aware of the world around her in the same way a baby is aware.
- In a Horrible Histories sketch, there was this exchange:
Kill counter: That makes 4,997.
Roman general: Make that 98.
Kill counter: Yeah, I'll give you that one. He's still moving, but realistically, he's not going anywhere without his head.
- In Illbleed, Randy's brain being removed turns him into a type 1. If you don't recover his brain before rescuing him, you'll instead rescue and unlock the ability to play as "Brainless Randy", who talks in random grunts and groans (that other characters can understand perfectly) and can't use the Horror Monitor due to having 0 adrenaline. Other than that, however, he's capable of doing pretty much everything regular Randy can do, making him a bit of a mix between type 1 and type 2.
- In Psychonauts when the villain makes the campers sneeze their brains out, they end up as mindless zombies only able to moan "Teeeee-Veeeeee...." and stumble to the nearest set to start watching. If Raz can find the jars holding the brains, he can return the campers to normal with no ill effects.
- In Crash Twinsanity, during the cutscene that introduces The Evil Twins, they remove Doctor Cortex's brain with their telekinetic powers. He is left drooling and clutching his brain afterward until one of the duo tells him that "This Is the Part Where... you run away, screaming." It takes him a beat to catch on, but he does exactly that. Shortly afterward, he's no longer holding his brain and acting normal, so he must have gotten it back in his head somehow.
- A short cutscene in The 7th Guest can be found in Henry Stauf's well-hidden laboratory. A ghostly patient wakes up moaning on an operating table, and we see that an entire half of his head is missing. He realizes this, looks down, and starts reaching for a CG brain sitting in a bucket down below. The scene ends before he can grab it, though. (Along with a horribly squicky noise.)
- Yeagar from Nodwick has his brain removed at least twice (once by an Illithid and once by an Evil Henchman). In the second case, Piffany drafted a nearby butterfly and put it in his cranial cavity. This, somehow, allowed Yeagar to stay mobile.
- Oblina of Aaahh!!! Real Monsters once sneezed her own brains out, leaving her body a drooling and mindless but mobile vegetable.
- The Ren & Stimpy Show: In "Ren's Brain", Stimpy takes out Ren's brain and replaces it with a telephone, leaving him a drooling vegetable. The brain, on the other hand, gets up and goes to work as if nothing has happened.
- Invader Zim:
- At the end of "Bad Bad Rubber Piggy", Zim sends a warning to himself back in time, but it has to replace something and that something turned out to be his brain. Rather than keeling over, he just kind of sat there, drooled, and moaned a bit. This is somewhat justified, as one (unaired) episode established that the Irken's (Zim's race) PAK (backpack-looking thing) is the actual "brain" of the organism, the body serving as something to carry the PAK around (though this does bring up the question of why there even is a brain).
- Another episode, "Dark Harvest", plays this trope straight. Zim, in pursuit of human organs to improve his human disguise, replaces a secretary's brain with a can of soda. Nothing happens immediately, but when the phone rings, she holds it up to her face and foams out the mouth.
- In the Men in Black: The Series episode "The Quick Clone Syndrome", Zed had his brain stolen. The procedure left his brain remotely controlling his body, manifested by him continually walking straight. The other agents blamed it on the thief's sick sense of humor.
- SpongeBob SquarePants tends to use this type. On the multiple occasions where a character's brain gets removed, they tend to stand around and drool until it is replaced. In Patrick's case, this is often indistinguishable from his normal behavior.
- This happens to Fanboy from Fanboy and Chum Chum in the episode "Brain Drain". His brain is evidently not subject to the laws of gravity, because it stays in mid-air while he is falling.
- In the Futurama episode: "How Hermes Requisitioned His Groove Back", when Bender loses his brain (in disc form), he loses his personality and resets to his factory default, which leaves him unable to say anything but "I AM BENDER. PLEASE INSERT GIRDER." He still walks around, but doesn't pay attention to where he's going in the slightest.
- In the Rocko's Modern Life episode "Boob Tubed" Heffer has his brain sucked out through the TV after sitting too close, he is reduced to a drooling idiot who spouts nonsense, repeatedly walks into walls, and thinks he can fly.
- The Grim Adventures of Billy & Mandy: In contrast to Billy, who doesn't have a brain at all to begin with, the victims of the evil, brain-sucking meteor in "Little Rock of Horrors" turn into zombie-like creatures who can nevertheless dance to the song the meteor sings.
- Happens in The Sylvester and Tweety Mysteries in the episode "This is The Kitty". When Sylvester refuses to spit out Tweety, Hector and the Jack Webb stand-in respond by yanking Tweety out, inadvertently removing Sylvester's brain as well in the process. After having his brain removed, Sylvester just stands there drooling.
- The Avenger Penguins episode "The Quantum Mechanic" had Caractacus P. Doom steal Bluey's brain, leaving the penguin silent and sitting around doing nothing.
- The Simpsons: At the beginning of "Itchy & Scratchy Land", while in a cartoon promoting the opening of the titular theme park, Itchy stabs Scratchy in the head with a pair of scissors. Scratchy pulls it out along with his brain, leaving him drooling.
- Anencephaly, when a child is born with no brain, only a brain stem. A disturbingly common birth disorder. About half are stillbirths. Most of the rest survive a few hours or days. However, The Other Wiki mentions a few cases of kids who survived a couple of years as a partial Reality Is Unrealistic case of this trope.
- Shufflebrain, a series of experiments involving salamanders, had animals with their brains removed who remained alive yet stupefied. Replacing the brain in various positions resulted in No Change with salamanders.
Stupid but Aware:
- Happens to Reiko Tamura in Parasyte when she splits herself in two in order to avoid being killed. As each parasite is only as intelligent as the parts that make it up, being separated causes her human half to become much stupider than she normally is, even physically showing off this trope by forcing her head in half in front of a couple to reveal it's hollow inside.
- In an episode of Sabrina the Teenage Witch Sabrina is infected by a Stupidity Virus, which leaves her literally empty-headed and a shallow boy- and shopping-obsessed Brainless Beauty in personality. There actually is a parasite that eats brains, but it's protozoan, not viral.
- In a Show Within a Show Stupid but Aware example one episode of the Saved by the Bell has the gang make a film about evil aliens invading. A history teacher (played by Jessie) had her brain sucked out her ear (via a straw) by an alien (played by Screech) while telling her class that "the Gettysburg Address was delivered by [brains sucked out]... Pee-wee Herman."
- Observer a.k.a. "Brain Guy" from Mystery Science Theater 3000 is an omnipotent alien who normally carries his brain around in a jar with him and routinely denies the existence of his body. (Essentially, he's a parody of the sci-fi trope of advanced aliens who evolved beyond the need for a physical body.) Then in the episode Space Mutiny, his brain jar gets moved too far away from his body, which leaves him babbling inanely to himself and misunderstanding simple instructions. He's still omnipotent in this state, but he's too stupid to do anything useful with his powers.
- Peri of Spliced ended up in a state somewhere between Types I and II: he was mostly incapacitated but could sorta walk around and mumble/scream for the return of his brain. When he found his brain had been implanted into a toaster (roll with it) he tried to shove it back in, toaster and all. It didn't work.
- Meatwad of the Aqua Teen Hunger Force, a literal living wad of meat, does have a brain, but it's just a rubber toy with a jingle bell inside. He was given it apparently because he felt deprived with no brain. When it's removed, he still becomes less intelligent, but this seems to be a psychosomatic effect.
- Kaeloo: After Kaeloo gets half her brain removed in one episode, all that happens to her is that she can't talk properly.
- The Foster's Home for Imaginary Friends episode "Cheese a Go-Go" featured a movie where a woman had her brain sucked out by aliens. When asked if she is alright, she replies with "Shhh, I'm hiding from the aardvarks".
- In one episode of Chop Socky Chooks, Dr. Wasabi's latest money-making scheme is to open a liposuction clinic that gives clients complementary burgers made with the fat that they just had sucked out of them. He falls into one of the liposuction machines himself and his brain gets sucked out, leaving him with the intelligence of an infant.
- The downplayed version of this trope (in which bits of brain are removed, leaving the victim slightly less capable) is very much Truth in Television. Depending on which part of the brain is damaged or removed, a person can fail to recognize faces, shapes, certain patterns in sound and colour, and even their own family members. Some of the effects can be weirder than a simple loss of ability, though: removing bits of the amygdala frees people from getting bogged down in emotion when making decisions, and forces them to become hyperrational, but at the cost of being The Ditherer for even minor decisions as every decision has to be weighed consciously. And it only gets weirder from there.
- In 1848, Phineas Gage had a pole jammed through his head that removed part of his brain. It didn't kill him, but he is said to have become much more cranky and dishonest after the pole went through his head. Though just how much impact the injury had in his personality is now questioned by psychologists, due to there being no actual records of what he was like before the accident aside from anecdotes that were recorded after. And due to many of the records being either vague or contradictory (for example, one doctor claimed that he had become sexually insatiable and would readily assault any woman he saw while another claimed that he'd completely lost all interest in sex).
- A rare inverted example was The Major from an old Time article. The man shot himself in the head with a .38 revolver.... He then went downstairs and cooked himself breakfast. He was later taken to the hospital where all the doctors could do was clean and dress the wound. Later he was interviewed and his long-lasting depression had vanished. The man shot himself in the head and got better.
- The page picture is of a Batman villainess named Una Nemo a.k.a. "The Absence". She is a rare dramatic (well...) example: Una has an enormous hole in her forehead and extending all the way through, with no visible brain, yet functions just fine, and may be smarter than before the hole happened. It appears to be a combination of a freak medical condition (which resulted in the brain lining the skull rather than sitting in the middle of it, meaning the through-and-through was more of a trepanation) and Gotham City's water supply being seriously tainted. The end result gave her Super Intelligence enough to outsmart the Bat on a scheme that (ironically) was meant to turn her into an Un-person, yet made sure that Bruce Wayne remembered her.
- In I Feel Sick, Devi reminisces about a particularly bad date she went on. A mongoose ate her date's brain, but he was so stupid to begin with that it took her a while to notice.
- Over the Hedge occasionally has strips where Hammy the Squirrel's mind leaves his body and roams around independently. Since Hammy is a Cloudcuckoolander at best, this usually has little effect on him.
- One strip in Calvin and Hobbes had Calvin let his brain wander off before losing it. Of course, this was just his imagination playing up.
- For a few days in Pearls Before Swine, Pig's brain goes wandering off on its own. Pig is mostly unaffected, with Rat using his empty head to hold beer.
- Planet 51: Once two alien soldiers have their brains removed, not only do they still function but actually seem to get smarter, such as speaking in Sesquipedalian Loquaciousness.
- In Suicide Squad: Hell to Pay, Zoom spends most of the movie strolling around with a hole in his head. Justified, as it actually was just as lethal as you'd expect, he just used the Speed Force to stretch out the fraction of a second before death, giving the impression that it hasn't effected him.
- In Addams Family Values Gomez and Fester are cheerfully reminiscing about all the (violent) pranks they pulled on each other as kids. Fester casually mentions that one time he waited til Gomez was asleep, then opened his his head and removed his brains. Gomez is surprised and sort of impressed by this revelation.
- Hard to say what category Eddie from The Rocky Horror Picture Show falls under as we are only given hints of his behavior prior to having half his brain removed. (We know he had a criminal record and thought "head" was spelled "hed".) He still knew how to operate a motorcycle, but tended to drive it indoors with reckless abandon. (He was a bit of a rebel to start with.) He only says the word "NOOOOOOO!" when Frank comes after him with a pick ax, which is one word more than Rocky says. (Not counting their songs.) So, he theoretically could talk and knew crazy guy with ax=bad. Not bad for someone with half a brain.
- In Pirates of the Caribbean: At World's End, one of Jack's hallucinations of himself briefly has this happen to him.
Jack: Nobody move! (beat) Dropped me brain.
- Scorpius on Farscape has two impossibly-large centrifuges on either side of his head that insert "cooling rods" into his brain. It was always a tongue-in-cheek special effect, but The Peacekeeper Wars confirms what we already suspected when the Scarran Emperor snaps one of them off. Scorpius' moll, Sikozu, has to mash two rods into the gaping cavity, which is filled with churning yellow goo. Then she power-drills a metal plate to his temple to make them stay in!
- In a Just Say Julie sketch a Dumb Blonde supermodel is given a tricky question and her (tiny) brain explodes out of her head with the effort of thinking... leaving her seemingly none the worse for wear and not even bothering to cancel a date at end of the show to get medical attention.
- A sketch on You Can't Do That on Television had a mother getting far too enthusiastic about cleaning out her child's ears, and cleaning out everything between them as well. It had no noticeable effect on the child (well, he wasn't happy about it but as his mother pointed out, even if she had cleaned out his brains he'd never used them anyway.)
- Brain Guy from Mystery Science Theater 3000 is a variant on No Change: while his brain isn't in his physical head, he does always keep it nearby in a dish. If his body gets too far from his brain he degrades into a Stupid but Aware. On top of all this, he and the rest of his species believe (in spite of all evidence) that their physical bodies don't actually exist.
- The Legend of Dick and Dom has an episode where the McGuffin is the brain of a prince called Dick. They eventually remove it from the one travelling with them, to no ill effects.
- A more serious example than most in Choujuu Sentai Liveman. Dr. Kemp removes his brain to enable the Big Bad to carry out his plan. This merely turns him into a One-Winged Angel, who serves as the Monster of the Week.
- Warhammer 40,000: Orks are renowned for being exceptionally tough and exceptionally stupid, to the point where it's joked/believed (in-universe) that the least dangerous way for an ork to fall is for it to land on its head. While they can survive decapitation and brain transplants (including with a squig), this is due to them being part fungus.
- In the Old World Blues DLC for Fallout: New Vegas, the player character has their brain removed (and their spine and their heart) and has it replaced with a bunch of machinery that basically connects their brain to their body wirelessly. When you find your brain towards the end of the DLC not only does it have its own personality, but you can opt to leave it out of your head for the rest of the game. With a couple of buffs even. And it even gets its own mention in the ending, if you leave it there, based on your karma.
- In Monty Python's Flying Circus, Mr DP Gumby has lost four pieces of his brain, and is working to recover them. It's difficult to tell from the game how much brain loss reduced Mr Gumby's intelligence, but on the show he doesn't show much intelligence to speak of.
- Oh Yeah! Cartoons:
- The short "Max and his Special Problem" had a man literally sneeze his brain out. Aside from twitching every time the brain is poked, he acts perfectly fine.
- In "Ollie and Frank", Ollie gets a brain for his Frankenstein monster dog Frank by removing part of the brain of an ordinary dog. The ordinary dog goes through the procedure just fine.
- In the Ren and Stimpy episode "Sven Hoek", both Stimpy and Sven can remove their tiny brains with no effect whatsoever.
- South Park:
- An unusually violent (by the standards of the trope) No Change example: in "Die Hippie, Die", Mayor McDaniels attempts suicide by shooting herself in the head. Just before she pulls the trigger the "camera" pans to the side, we hear the gunshot and see blood and bits of brain matter hit the wall. Later in the episode she turns up alive and completely unfazed by blowing her brains out, with only a bandage wrapped around her head (with bloodstains on both sides of her head) indicating she'd shot herself.
- In an even more violent (and extreme) example a different episode has Britney Spears survive a self-inflicted shotgun blast to the head to that leaves her with nothing above her lower jaw. Since her "speech" is now incomprehensible it's difficult to know which type she is, but possibly a Stupid but Aware (she seems too aware of the outside world to be a Vegatable). This was apparently based on Mike the Headless Chicken.
- The Simpsons:
- Mr. Burns, having survived being buried under a landslide, is trying to get the dust and grit out of his ears by tilting his head and banging on the opposite ear. His walnut-sized brain shoots out of his ear and lands on the floor.
Mr. Burns: Oops. That stays in. (pops brain back into his ear)
- In another episode Selma insults Homer by saying he has a brain "the size of superball". Cue a cutaway to Homer's tiny brain bouncing around inside his head till it gets stuck in one of his ears, pops out his head and bounces away down the street. Homer is not only unaffected but actually seems pleased to see it go.
Homer: And stay out!
- His brain, or at least conscious mind, has also walked out on him out of boredom or disgust a few times.
- Mr. Burns, having survived being buried under a landslide, is trying to get the dust and grit out of his ears by tilting his head and banging on the opposite ear. His walnut-sized brain shoots out of his ear and lands on the floor.
- The Futurama episode "Roswell That Ends Well" has Bender's brain (a collection of computer chips) being mistaken for food and eaten. Bender isn't happy but he suffers no ill effects.
- In the beginning of the episode "Dollar Day" of Fanboy and Chum Chum, Fanboy's brain falls out when he trips, as a part of a Brick Joke. Later in the episode, when he and Chum Chum are trying to figure out how to get a dollar, he exclaims "We've got to THINK!", after which Chum Chum leaves the screen for a second to return with Fanboy's brain and places it back in his head. Throughout the episode, there's no difference in the brainless Fanboy's behaviour from his brain-equipped self (but he does make up a plan once he has his brain).
- In one episode of The Grim Adventures of Billy & Mandy, Billy's dad accidentally eats his own tiny brain and is no less stupid than before. He also once had his brain removed during an Alien Invasion and talked differently but was otherwise the same.
- In another episode, Billy is in the future with Fred Flintstone centuries after Billy found him in his yard. Fred's brain is promptly eaten by one of two alien overlords, but Fred is fairly indifferent toward it.
- In The Amazing World of Gumball, Gumball's brain gets out of his head after studying too hard. Gumball is unchanged, as he tries to train his brain so that it becomes smarter.
- The Fairly OddParents:
- In one episode Timmy drinks a smoothie too fast and get a brain freeze, which Cosmo replies to with "Brain? What is this "brain" you speak of?" and then proceeds to drink the whole smoothie in one slurp. "Nope.. nothing." Later, Cosmo and Wanda disguise as smoothies. Cosmo drinks himself in one slurp and still feels nothing.
- Which is weird, because in another episode Cosmo got a brain freeze from licking himself after he turned into ice cream.
- Whenever a character on the show — even if they are not The Ditz — removes the top of their head, there will be nothing inside it.
- In an episode, Entree's brain catches on fire when he memorizes the entire dictionary. Aside from occasionally shouting random words, he suffers no ill effects. This also is apparently common enough for Peri to be able to tell.
- In another episode, he is turned inside out, and is shown to have no brain.
- In another, he is told that if he loses a game, he'll receive 10,000 volts of electricity to his cerebral cortex, and retorts that he doesn't have one of those.
- In another, a mole-ster takes control of his brain and gets him to punch himself, so he pulls out the brain and pushes the mole-ster off.
- In another, his brain, stomach and heart leave his body after getting sick of all the abuse they heap on him. He remains unchanged.
- Mad Jack the Pirate: In one of the episodes, Jack gets a deadly disease that can only be cured by eating specific berries from an island of unknown location. Once they arrive there, Jack quickly starts eating the first berries they come across as soon as Snuk reads from the medical book that it should be these ones. However, as Snuk reads further into the book, it turns out that these particular berries actually cause the eater's eyes and brain to explode. Cue Jack spitting all the berries immediately, but still having both his brain and his eyes shoot out of his head. In the next scene, he holds both in a mug filled with water but is otherwise fine.
- In The Secret Show episode "And That's for Helsinki", both Victor and Anita find out that significant 'chunks' of their brains were removed by Professor Professor to be cleaned after they were hit by a mind bomb. Other than some slight amnesia they suffer no ill effects, even though the brain 'chunks' are big enough to look like they make up most of their brains.
- The plot of one episode of Brandy & Mr. Whiskers is that Whiskers' brain leaves after getting fed up with Whiskers not listening to him, but Whiskers is otherwise unaffected.
- The Histeria! episode "Really Oldies But Goodies" had a segment where Chit Chatterson demonstrated the steps of mummification on a living man in spite of his protests. When they get to the part about the Ancient Egyptians removing the mummy's brain, the man being mummified against his will suffers no ill effects and his only reaction is to complain about having his brain removed.
- The premise of the SpongeBob SquarePants episode "Whirly Brains" is that a new toy comes out that turns the user's brain into an RC helicopter. The users don't seem affected by the loss of their brains other than their eyes being still attached to them.
- The Bonkers episode "Stressed to Kill" has Fall Apart Rabbit experience this when his brain falls out and shows no reaction. Somewhat mixed with "No brain to lose" case in that the brain in question turns out to be a peanut.
- In the Teen Titans Go! episode "Head Fruit", Beast Boy's brain escapes, so when the other Titans fail to get it back, they replace it with a maraca to replicate the rattling that his brain produced and he can't tell the difference. He has his brain back in later episodes, including one scene in "Had to Be There" where he pulled it out of his ear and was unaffected.
- In Captain Simian and the Space Monkeys Rhesus-2 is a cyborg monkey with an exposed brain that he can remove and replace easily, and seems fully functional without one though he still has a habit of yanking his brain out and shooting it ("Bad brain!") whenever he messes up. Though, in one episode his original brain is re-inserted, which has the memory of his extremely painful cyber-conversion, leaving him catatonic.
- In the Gravedale High episode "The Grave Intruder", Coach Cadaver at one point briefly removes his own brain and is still able to function without it.
- In a bizarre variation, the Sealab 2021 episode "I, Robot, Really" ends with Quinn transferring most of the cast's brains into robots and turning the rest of their bodies into Mobile Suit Humans piloted by mice. Once Quinn "perfects" the latter process (i.e. putting the top of their heads back on instead of just a glass dome, so they look the same), the bodies wake up and act as if they're the original people, though hungry for cheese.
- Biker Mice from Mars: Fred the mutant has had his brain shot out, transformed into a vicious monster, and replaced with an alarm siren. He kept on living with no trouble at all, and being a masochist, he actually enjoyed the pain.
- In the American Dad! episode "The Chilly Thrillies", Steve has his brain run through with a piece of rebar and is no worse for wear beyond thinking that a secret admirer note he wrote for a girl was written to him.
- Mike the Headless Chicken. Though not all of the bird's brain was gone. Quoting Wikipedia: "The axe missed the jugular vein, leaving one ear and most of the brain stem intact". Still, it is impressive.
- Some animals:
- Octopi are capable of thinking with their tentacles as well as their brain, so they can still move even with just a tentacle.
- Frogs are still capable of various movements even without a head, though they do still experience some changes. However, a frog with its brain removed but its head still on, continues to act pretty much the same, and in fact has better reflexes than a frog with a brain.
- Fruit flies can survive, fly, and even react to light sources without a head because insects have a ventral cord (which functions like a second brain) in their chest and light-sensitive cells in their kidneys.
- A turtle's heart can keep beating unaffected even if removed from the body due to very strong cells that act as pacemakers.
- Cockroaches can survive a few days without their head.
No brain to lose:
- During the battle between All Might and All For One in My Hero Academia, the former finally gets the upper hand against the latter when he manages to land a point-blank punch against his head, which under most circumstances should have been lethal a million times over... only for it to cave with no apparent affect. Turns out he's been storing his Brain in a Jar, and the battle continues. Definitely not a funny example.
- Vanessa, the Dumb Blonde heroine of the French comic Les Blondes once had a doctor give her a CAT scan. When she asked if he had found anything the visibly baffled doctor showed her the X-ray of her empty cranium and replied: "nothing... absolutely nothing."
- In the original comic-book version of MAD, The Shadow uses his ability to turn invisible, by "clouding men's minds," on a group of baddies. Nonetheless, a dopey-looking mook manages to find him and klonk him on the head. Recovering quickly, the Shadow realizes, "Good heavens! This man doesn't have a mind to cloud!"
- In the film version of My Favorite Martian Marvin takes the shape of airheaded reporter Brace Channing. This isn't the only time he takes human shape and it's implied he has some sort of mind meld type connection with the brain of the real person he is copying. Unfortunately for him he picked Brace.
- Martin (visibly shaken): "Boy, her head was dark and empty."
- In What Women Want the protagonist Nick gain the power to read women's minds due to a freak accident. Trying to get away from the cacophony of thoughts being broadcast at him he seeks refuge in his office and encounters his dimbulb assistants Margo and Eve, who after greeting him simply stare at him vacantly. To his surprise he gets absolutely no thoughts from them at all and since he at one point heard the thoughts of a female dog the duo must really be brainless.
- Robert A. Heinlein's Time for the Stars, invoked by one twin insulting the other:
Twin 1: I know, she hypnotized us!
Twin 2: No. Granted I could be, but you couldn't. Nothing there to hypnotize.
- In the Star Trek parody Treks Not Taken, there's a Moby-Dick spoof where the Captain says that as the sailors of old had the sea in their veins, "I have the emptiness of space inside my head."
- Dr. Greta Helsing: Mummies are effectively Made of Magic and suffer no ill effects from the removal of their brains during mummification. Moreover, residual brain scraps can interfere with their minds, so it's actually better for them to have them cleanly extracted.
- In the I Dream of Jeannie episode "Who Are You Calling a Genie?" Jeannie loses her memory after hitting her head. She's taken to hospital but when her head is X-rayed it turns out to be empty. It is not clear whether this a trait common to all genies or Jeannie in particular.
- The short lived sitcom The Pitts about a Born Unlucky family had a Bratty Teenage Daughter named Faith (played by Lizzy Caplan). In one episode an accident with a drain pipe left Faith with a tennis ball sized hole all the way through her head, just above her ears, without any effect to her personality or intelligence (in fact she doesn't even realise anything has happened until she notices the others staring at her.) Given the fact that a mystified doctor notes there is 'no damage' and there is no visible brain matter even after the pipe is removed the (unstated) joke is that Faith didn't have anything between her ears to damage.
- Starbound: The Novakids are a race of aliens whose bodies are composed of homogenous, super-heated plasma shaped into a humanoid form, and as such nobody knows exactly how they think, breathe, eat, or do any other normal functions. They are also extremely absentminded, as they can't remember things for long, never bother to write down things they've discovered, and keeps reinventing all their technology, which many fans attribute to their lack of an actual brain. (Despite this, they are actually incredibly intelligent, as they can reverse-engineer spaceship tech just from having seen it before.)
- Quilt in Dominic Deegan is an Artificial Human (specifically a Flesh Golem) with no brain. He is fully capable of speaking, acting, and thinking, but he's an utter Cloudcuckoolander. He is, however, immune to brainwashing — "No brain to wash!"
- Unsounded: The Undead man Duane's brain rotted out of his skull years ago, which, while hideously traumatic at the time, left his mind intact. Discussed when he realizes that he now has perfect recall of his entire life without his brain interfering with his thoughts.
- In one episode of The Baby Huey Show aliens abduct Baby Huey to perform experiments on him, at one point they take an X-ray of his head, in place of his brain is a spider and cobwebs.
- In The Grim Adventures of Billy & Mandy episode "Brown Evil", Mandy reveals the reason why she sent Billy outside to deal with the zombies is that he has no brain. She then shows Hoss Delgado an X-ray of Billy's skull and a screw is shown where his brain should be. However, in later episodes, him having a brain is alluded to and he's shown to have one in "The Nerve".
- Lampshaded in one Growing Up Creepie episode. Creepie's adopted insect brother Gnat is buzzing around her, trying to annoy her and when Creepie turns to glare at him he flies into her right ear, cackles 'Hello, anybody home?' and exits her left ear still laughing.
- One episode of Kaeloo suggested that Stumpy may actually not have a brain.
- B.O.B. from Monsters vs. Aliens and its sequel TV series. As the page quote shows, his lack of brain makes him extremely stupid. One episode of the series had him insert a mechanical brain into his body, which turned him into an Evil Genius. Another episode showed that having no brain makes him immune to having his memories erased (unfortunately, he wanted to have them erased at the time).
- While it's true that people can't live without any brain at all, it turns out that half a brain is plenty enough. There was once a young woman born with only one working hemisphere, but aside from a few subtle edge-cases, she was perfectly normal. Her condition was only discovered when she volunteered as part of the control group for a study involving severed corpus callosums, and her results were not what was expected.
- A lot of stranger animals in the wild don't have brains and instead have nervous systems that do the thinking instead, like Jellyfish. The Xenophyophore is an eight-inch long underwater Amoeba that has a collection of thousands of Nuclei instead of any kind of brain.