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Opposite-Sex Clone

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Elliot, El Goonish Shive

While clones and most other sorts of sci-fi duplicates are identical to the original character and, by definition, the same sex, exceptions do exist. The idea dates at least from Nine Lives by Ursula K. Le Guin (1969), where recognized geniuses are routinely cloned in large mixed-sex groups and Time Enough for Love by Robert Heinlein (1973), where the opposite sex clones become sexual partners of the original. Nowadays the trope is more often used as a quick way of producing a Distaff Counterpart rather than for titillation. Merely being of the opposite sex of his or her original greatly increases the chance of the clone surviving the denouement and showing up in a future story. This way writers can invoke the First Law of Gender Bending without sacrificing an original-sex character they've grown fond of.

Biologically, this is somewhat plausible for male-to-female cloning, because a male has an X-chromosome that can be doubled to produce a female clone, as in Garrett's poem and Heinlein's novel.note  Alternatively, the SRY gene, which causes maleness, can be removed from the Y chromosome. For female-to-male cloning, the Y chromosome would have to come from another subject, preferably a paternal relative and most ideally the father, as if the original subject were a male, she would have had a Y chromosome virtually identical to her father's. Nevertheless, this would technically not be a pure clone. A Y chromosome could be formed from one of the X-chromosomes, which would require absurd amounts of genetic engineering and amount to simple fiat anyway. Alternatively, the SRY gene can be implanted in one of the X chromosomes to create a sterile clone that appears male. Somewhat fittingly when given the above, the majority of these characters are female.

If the Opposite-Sex Clone retains the memories and personality of the original this is effectively a Gender Bender, at least from the perspective of the clone.

See Clone Angst for when said clone is upset about their nature. Subtrope of Modified Clone and Our Clones Are Different. Compare Distaff Counterpart, Half-Identical Twins and Screw Yourself. See also Trans Audience Interpretation, as that is a common fan explanation as to why this trope occurs.


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    Anime & Manga 
  • In Magical Girl Lyrical Nanoha StrikerS, Uno of the Numbers Cyborgs was revealed in the Sound Stages to have been created by Jail through cloning, using his own genetic material.
  • Ranma ½:
    • After accidentally looking into an enchanted mirror, Ranma creates a copy of his female self. She is, of course, infatuated with him. In the end, he accidentally copies his male self and the two copies fall for each other.
    • In an anime episode, Happosai attempts to split Ranma into male and female forms for his own selfish reasons. However, he misses the fact that, A: Ranma despises him and would never obey him no matter the form, and B: the incense he uses is called Personality Splitter. The result is an Enemy Without situation, as the Clone is a vampiric ghost-like entity that is the living embodiment of Ranma's evil.
  • The title character of Battle Angel Alita: Last Order and several others are cyborg clones of the same woman. Sechs was original female, but decides to alter their body to be male.
  • The female Nemu is the clone of the male Mayuri Kurotsuchi in Bleach. It's more apparent when Mayuri doesn't have his make-up on.
  • In the Starship Girl Yamamoto Yohko TV series, Yohko's male clone, Yousuke appears. He turns out to be female and in disguise, but then actually becomes male later.
  • Getter Robo Armaggedon: the pilot Go is a male Artificial Human made from the DNA of Dr. Saotome's deceased daughter Michiru.
  • In the hentai manga Alice's Adventures in Sexland, obviously an erotic retelling of Lewis Carroll's book, there is a furniture maker whose furniture is special because it will spring to life and play with the user. Her "masterpiece" is a mirror, which sprung a magical clone of Alice, because, as the creator says, Who knows best what you like and what you need, if not yourself. Only it wasn't an exact clone. She does state, however, that the mirror would have given a perfect clone if that was what Alice had wanted.
  • The former trope picture is from the artist Pisipisi and is of a series of drawings where a perverted Mad Scientist college student clones the girl he's stalking — but puts his own mind in the clone instead of her's. Of course, then "she" wakes up, realizes that "she" now has a horny pervert expecting "her" to be a personal sex toy for him and his friends, and is less than enthused about the idea. Then she discovers that his male mind has no defense against female erogenous zones... Unfortunately, Pisipisi banned all American visitors to his website years ago due to harassment, and (possibly due to rumors of "Pisipisi" being the pen name of professional artist Saiwase Okiba) frequently goes months or years without updates.
  • Keith Violet of Project ARMS, the one female amongst the many clones of Keith.
  • Yu-Gi-Oh!, it isn't a clone exactly, but the digital copy of Mokuba Kaiba that Seto Kaiba creates in a video game is Princess Adina. It makes a bit more sense in the Japanese version, where the Big 5 programmed the female Mokuba rather than Kaiba.
  • The Innovators in Mobile Suit Gundam 00. They are all technically genderless but come in pairs; out of the four pairs only one has both members having adopted a persona of the same gender (both male), so each of the other six Innovators has their own opposite sex clone of sorts.
  • One of Naruto's techniques involves either transforming into and occasionally summoning several more, scantily clad female versions of himself. And by "scantily clad", we mean "clothed in convenient smoke".
  • Darker than Black Gemini of the Meteor reveals that Suou is an opposite-sex clone that Shion created of himself to pass as his twin sister complete with Fake Memories. The real Suou died during an unrelated assassination attempt.
  • Knights of Sidonia: Norio Kunato's "sister" Mozuku is in fact a clone of himself, but altered to be female. She takes care of all of Norio's responsibilities as head of the Kunato family while he devotes his time to piloting, and is mostly just seen as an extension of Norio himself.
  • Ayakashi Triangle: About half a year after Matsuri was turned from a boy into a girl, exposure to The Corruption somehow resulted in both a male and female Matsuri, each with all of Matsuri's previous memories and personality. Because only the girl has the mark of the initial transformation, it's judged most likely the spell was turned into an ayakashi with a copy of Matsuri's mind, turning the original back into a boy. However, it's entirely possible the boy is a clone, and thus an inversion.

    Comic Books 
  • After Fantomex of the Uncanny X-force died, he was going to get a cloned body to come back with. However, he has three different brains and each brain received its own cloned body. The nicest brain got a female body called Cluster.
  • Spider-Woman (who later went by Black Widow), in Ultimate Spider-Man. Ultimate Spider-Woman is a clone of Peter Parker, with all of his memories and personality traits - except she's considerably more abrasive, especially to Miles. (They were going to blank her memory and give her an entirely new made-up personality and set of memories, but didn't get around to it before wackiness ensued.)
  • X-23 is an Opposite-Sex Clone of Wolverine, developed by Dr. Sarah Kinney as a solution to not being able to recreate a Y chromosome from a sample of Wolverine's DNA. So instead, she doubled the X chromosome.
  • Also in Marvel, The Collector (whose hobby with species is exactly what his name suggests) captured both Howard the Duck and Rocket Raccoon, and proceeded to create female clones of both, named Linda and Shocket, respectively...for a breeding program. Both managed to survive and become their own individuals. (Incidentally, this suggests the Collector isn't as good at his job as he seems, since while there are only one of Howard's species in their universe, there is a female Halfworlder raccoon out there named Captain Sale.)
  • Used in a classic Supergirl comic where a criminal tries to clone Supergirl in order to use her twin to commit crimes. The (male) twin ends up committing suicide due to an Ethical Conflict between what his criminal creator has told him to do and what his twin wants him to do.
  • In Spider-Gwen, The Falcon is the teenage, male clone of Captain America, who is a black woman named Samantha Wilson in this continuity.
  • One Judge Dredd story set during a flashback to Chaos Day portrayed a group of cadets trying to survive. One of them is stated to be a Dredd clone. Falcone is the obvious, but wrong, candidate. Turns out the clone is female. And pregnant.
  • In DC Comics Bombshells, Superman is an opposite-sex clone of Supergirl, created by Hugo Strange. He also created a same-sex clone, who is that continuity's Power Girl.
  • Wonder Woman (1987): Kreel biology means that attempting to clone a man may result in a female infant, as is the case for the Emperor.
  • X-Cellent introduces Phatty, a female clone of Phat, one of the dead members of X-Statix.

    Fan Works 
  • Naruto fanfictions happen to do this a lot to the main character, due to his Opposite Sex Clone actually being real. This is strengthened in the fact that it's not really a clone, but a disguise that quite literally changes Naruto into a girl. He can do this to his clones making literal Opposite Sex Clones.
  • Kid Icarus Uprising 2: Hades Revenge has the main character, Cloud Angle, create one, named Azul. Her first scene involves her and Cloud as a plan to avoid becoming virgin sacrifices.
  • The Bridge: As a visual gag. Changelings can only mimic ponies of the same sex, so when a female one tries to mimic the transformed kaiju-to-unicorn Godzilla Junior the result is a female version of Junior.
  • Hero: The Guardian Smurf: Wonder Smurfette is one of the series' main protagonist Hero Smurf, who was created with the magical Mirror of Opposition when lightning struck it, thus creating a second adult female Smurf in the village besides Smurfette.
  • Sunsplit Saga: Basically the core idea of the saga, and a First-Episode Twist, Sunset Shimmer is Sunburst's magical construct clone, whom he made to take on a date.

    Film — Animated 
  • The Nightmare Before Christmas: Dr. Finklestein builds a female version of himself out of body parts around his lab. While not a genetic clone, he does give her a half of his brain.
    Dr. Finklestein: We'll have conversations WORTH having.

    Film — Live-Action 
  • Logan: Laura was created from samples of Wolverine's blood, doubling the X-chromosome.

  • BattleTech Expanded Universe: The Clans are a race of supermen and women that are mass-produced in batches from the DNA of their greatest warriors. During their childhood, all the clones engage in casual sex with each other to build bonds. This sometimes continues into adulthood, such as the Pryde siblings from the novel Legend of the Jade Phoenix and the Hazen siblings from the Mechwarrior: The Dark Age novels; both from Clan Jade Falcon. Maeve Wolf, of the Wolf's Dragoons, is secretly a sex-swapped clone of Jaime Wolf.
  • Biting the Sun: The heroine goes male so as to be able to produce sperm which s/he stores, then uses (once she switches back to female) to impregnate herself. It doesn't end up that well...
  • In "A Clone At Last", a short story by Bill Pronzini and Barry N. Malzberg, a man commissions a female clone of himself because he has no luck with women.
  • Dune:
    • God-Emperor of Dune: Leto is introduced to Hwi Noree, the new Ixian Ambassador, who turns out to be an Opposite Sex Clone of the previous ambassador, genetically tweaked to be irresistible to the inhuman Leto.
    • Dune Encyclopedia provides a history of all of Leto II's Duncan Idaho gholas, it includes that the Tleilaxu once provided a female Duncan Idaho ghola in a similar ploy to what the Ixians attempted with Hwi.
  • Forges of Mars: The scientist Linya Tychon is a female clone of her father Vitali Tychon. He’d intended her to be male like himself, a carbon copy existing solely to carry on his work when he died, but an error in the creation process altered her sex and inspired him to treat her like a daughter instead.
  • Genome: In Dances on the Snow, a genius geneticist named Edward Garlitski manages to create a female clone of himself named Ada Snezhinskaya. She shares his ambition and a vision of a world where genetic engineering is the norm. However, they have different ideas on how to achieve this goal. He chooses to work within the system by perfecting genetic engineering (in another book he is hailed as the father of genetic engineering). She decides that the entire society needs to be remade through political means. She creates hundreds of clones of herself and Edward and sends them out throughout The Empire to be adopted by unsuspecting parents. She then plots a rebellion, which would result in her ruling with her clones. Her plan fails but Garlitski's succeeds.
  • In House of Suns, by Alastair Reynolds, the various posthuman clone houses, such as Gentian Line, consist of male and female clones of a single individual.
  • InterWorld: Joseph Harker, after accidentally traveling between dimensions for the first time, realizes that he has been replaced in this dimension by Josephine Harker, an almost-exact female copy of himself.
  • Nine Lives by Ursula K. Le Guin: From 1968, it's possibly the oldest example in modern SF. Earth is in a sorry state, most people suffer from inborn defects. To remedy the situation, the best people are cloned. Usually, the donors are male, since it allows to easily clone both sexes, and mixed-sex groups of clones are proven to function better.note  The story explores the reaction of normal humans who have to work with a "ten-clone" created from a genius who died young. And then how the sole survivor reacts to the death of his 9 siblings. Among other things it's mentioned that clones routinely share sleeping bags and sex seems just as natural for them as breathing. An observer wonders if it's sex or masturbation.
  • Otherland: The Corrupt Corporate Executive Felix Jongleur's daughter is a clone of himself. She's actually a byproduct one of his early attempts to make himself immortal. The idea was to have a clone of himself implanted in a surrogate mother. Of course, the child would need a similar upbringing to his own to produce an effective copy. To this end, Jongleur wanted the surrogate mother to be like his own mother. Unfortunately, he couldn't bring himself to unearth her body... so instead, he made an Opposite-Sex Clone of himself. That's right: he intended to impregnate an opposite-sex version of himself... with himself. Very Squick. Fortunately, the project never went beyond the initial stages because a far more appealing (yet no less unethical) option presented itself, so Jongleur adopted the Opposite Sex Clone for his daughter.
  • After being murdered several times, the protagonist of The Phantom Of Kansas eventually hooks up with her murderer (an illegal clone of herself that has undergone a sex-change) and buys a spaceship to head out for the most remote settlement in the solar system.
  • In James Patrick Kelly's story "Solstice," one of the main characters has himself cloned as a woman. Later he turns it into Screw Yourself. He eventually has a moral epiphany and is filled with guilt, both about the incest and his selfishness in cloning himself.
  • The Stardoc series has for a main character Cherijo Grey Veil, who is introduced as the daughter of renowned geneticist Dr. Joseph Grey Veil. Later in the series, we discover not only is she a female clone of the good doctor, she was created as a wife for him. Basically, he was such an egomaniac that he felt only his Distaff Counterpart would be a worthy mate. And he was willing to get laws passed declaring her a non-person in order to make sure she had no say in the matter.
  • The character of Lazarus Long in Robert A. Heinlein's book Time Enough for Love is the world's oldest living human. At the beginning of the book, he is trying to kill himself by avoiding "rejuvenation therapy", and a squad of his descendants rescues him. He makes a deal with them: he will go through rejuvenation therapy if they can unearth one experience he could do that he hadn't done already. Two of his female descendants arrange for Opposite Sex Clones of him to be implanted in them; both are born, and he finds himself raising twin female versions of himself.
  • Lois McMaster Bujold's Vorkosigan Saga:
    • Not quite the same, but it's stated in various novels that opposite-sex clones are possible, and that the corrupt rich people who choose to have their brains transferred into a younger clone sometimes pick this option (with optional plastic surgery beforehand, to make sure it's a pretty clone).
    • It's implied in Mirror Dance that some people order clones of themselves chiefly for the purposes of sexual experimentation, although the opposite-sex option isn't brought up at that point. It's also stated outright that the mass-produced Durona Group are of both sexes, although there seem to be more females than males. (The original is a woman.)
    • In A Civil Campaign, Lady Donna Vorrutyer becomes Lord Dono thanks to a cloned set of male anatomy. The missing Y chromosome was supplied by her dead brother. Ivan gets really squicked by all this because he had previously had an affair with Lady Donna.

    Live-Action TV 
  • Doctor Who: In "The Doctor's Daughter", a female Truly Single Parent-offspring is made of the Tenth Doctor. She's a genetic duplicate made of a tissue sample, entirely against his will. The relationship between them is presented as father/daughter throughout, as she was created from splitting his chromosomes then randomly recombining them — like sexual reproduction, but him being both parents. The Doctor calls her a "generated anomaly". Donna shortens that to "Jenny". note 
  • Orphan Black focuses on several clone characters played by Tatiana Maslany. One of them, introduced in Episode 8 of Season 2, is a trans man named Tony (formerly Antoinette). In Season 3, the focus is on Project CASTOR, which involves a series of male clones that are genetic siblings to the female clones. In fact, both lines come from a single donor, who happens to be a genetic chimera, having absorbed her male twin brother in the womb and thus has two sets of DNA.
  • Red Dwarf:
    • "Parallel Universe" has opposite-sex versions of the whole crew, where Rimmer's female double (Alternate Universe rather than cloned) comes on to him in a spectacularly unsubtle way, and where Lister proceeds to sleep with and get pregnant by his female counterpart. This episode also features an obvious joke:
      Arlene Rimmer: [to Lister] What could possibly have made you contemplate... making love to yourself?
      Arnold Rimmer: Well, why break a habit of a lifetime?
    • "Rimmerworld" has Rimmer try to go the pervy route with this when he winds up stranded on an unoccupied planet. He screws up the cloning, though... several times. Even when he gets it "right", the clone still has his (male) face, but by that time, he's a prisoner of his own male clones and thus has bigger problems...
      Rimmer: Technically, she would be my sister, and therefore unable to take me as her lover. After much soul searching, I reluctantly decided, "What the hell", I just wouldn't tell her.
  • Sliders:
    • An episode has Quinn meet Logan, his Distaff Counterpart. Turns she actually is him—in this universe Quinn was born a girl. She's also an Evil Twin.
    • In another episode Quinn is on a talk show and mentions meeting Logan, and of course the host immediately asks if he slept with her. They did kiss, though for his part Quinn was unaware of the connection at the time.
    • It's interesting that Logan found out that Quinn is her double via a "thermal scan", basically, an advanced biometric system that maps each person's unique "heat signature". The Fridge Logic comes from a man and a woman having the same heat signature, even if they do share the same parents.
  • Star Trek: The Next Generation: When a non-corporeal entity impregnates Troi in "The Child", the baby is half-Betazoid and half-human, just like its mother in every way, except male.


    Mythology and Religion 
  • In many Mesoamerican and Southwestern Native American cultures, the gods often come in male-female pairs. Whether they're intended to be different aspects of the same god, brother and sister, husband and wife, or this trope is not always clear.
  • In The Bible, it is said that Eve was created out of Adam's rib, making her for all intents and purposes one of these.

    Tabletop Games 
  • BattleTech General Maeve Wolf of Wolf's Dragoons is a female clone of founder Jaime Wolf. Rumors had it she was his illegitimate daughter even though public records claimed her as one of the war orphans the company took in while their own records had her as one of their Trueborn warrior of such mixed heritage that she refused a proper Bloodname.
  • Traveller: Archduke Norris Aella Aledon never married, but needed an heir, so he had a daughter (Seldrian Aledon) created. Cloning to have children happens so often, there is a term specifically for clone offspring (especially ones created to provide an heir for nobles): "true-son" or "true-daughter".

    Video Games 
  • In BioShock Infinite, it turns out that Robert Lutece is not Rosalind's twin brother, but rather an opposite-sex version of her from an alternate universe.
  • The Crusader Kings II mod Crisis of the Confederation, being a space opera mod, includes cloning as a possibility. Males cloning themselves can choose whether the clone will be male or female (females can only make female clones, though).
  • The female version of Alex in Deus Ex: Invisible War is a clone of Paul Denton.
  • In Drakengard 3, each of the Intoners has their own Disciple to serve them as a companion, bodyguard, and to sate their ramped-up sexual needs. Instead of a normal Disciple, One somehow spontaneously created a male clone of herself, who she keeps hidden from the other Intoners as a secret weapon against Zero. He only appears in the main story at the very end of Branch A, as a Diabolus ex Machina who backstabs Zero out of nowhere, but he co-stars in One's DLC missions, turns out to be the founder of the Cult of the Watchers that features so prominently in Drakengard, and is the main character of the Drakengard 3 spinoff manga. And yes, One used her brother to meet her sexual needs as well - she at least felt guilty and conflicted about it, he didn't see what the problem was. And no, he isn't given a name beyond One's Brother, and in Route A's epilogue is able to pass himself off as One to take her place.
  • A very important and hidden sidequest in Elden Ring reveals that Radagon is secretly Queen Marika's 'male half', with his own will and distinct personality but intrinsically connected to the God-Queen. Though Radagon's exact origins are unknown, it's implied that he physically split off from Marika at some point in the past, and that just before or right after the Shattering he fused back with Marika, as they presently share the same body, which shifts depending on who is in control. The two are actually remarkably similiar physically, with Radagon simply having a more obviously masculine build and red hair, while Marika has a more feminine (though still imposing) build and blond hair.
  • In The Elder Scrolls III: Morrowind, Divayth Fyr (a very powerful, very old wizard), made four female clones of himself: Alfe, Beyte, Delte, and Uupse. They're variously described as wives or daughters. Surprisingly this isn't particularly played for Squick... at least within his tower.
  • Endless Space has the Horatio faction, an array of clones of ultra-rich Horatio the First. Some of them are female, because Horatio got bored with just his male clones.
  • The King of Fighters series has Kula Diamond, one of the many clones of Kyo Kusanagi. In addition to the sex flip, Kyo's powers over fire became Kula's powers over ice.
    • The series can be inconsistent about "clones," sometimes using the term to describe unrelated people who have just been altered to be like someone else, and not clones in the normal sense. This makes Kula's status as a clone unclear.
      • Kula did say in her storyline in KOF 2001 that she was "grown from a petri dish" (at least in the English version, anyway), which would make her fall squarely into this trope.
      • However, Kula's bio in Maximum Impact 2 hints that she's a clone in the "genetic manipulation" sense (i.e. a normal girl surgically implanted with Kusanagi DNA, much like K' and Nameless). While the MI series is an Alternate Continuity, most of the characters' backstories seem to be unchanged, so...
  • In Kingdom Hearts: 358/2 Days, Xion is a clone of Sora literally made out of memories. It's played with a bit, as what you see while looking at them varies from person to person (such as Xigbar seeing her as Ventus), but the Shapeshifter Default Form is Kairi with black hair.
  • In Mass Effect 2, Miranda Lawson is genetically engineered using her biological "father's" modified genome to be perfect. Unsurprisingly she has some pretty severe daddy issues resulting from what she perceives as her father's egotistical arrogance. Ultimately by the end of 2 and in 3, they turn out to be two VERY different people, with Henry Lawson turning out to be even worse than Miranda described and Miranda showing herself to be a Jerk with a Heart of Gold, with the Jerk part eventually being shed.
  • By the time of Mega Man Zero, the four Guardians were created from Mega Man X's DNA. One of these Guardians is the obviously female Fairy Leviathan.
  • Nintendo Wars: Caulder/Stolos from Advance Wars: Days of Ruin has his 'daughters', Opposite Sex Clones of himself. They don't look that much like each other, so he appears to have fussed about with their genetics a little (which could explain their different eye colors). He does have a male clone as well, Cyrus, but he plays little part in the story.
  • In The Sims 2, a cheat can be used to impregnate a Sim by him/herself. Doing this will produce offspring that is a clone of the parent, but it will always be of the opposite sex. Notably, the child Brandi Broke is pregnant with when first played is such a clone, and isn't genetically related to his supposed father at all.
  • In the Street Fighter series, Cammy is a female clone of M. Bison (Vega in Japan, or simply "Dictator" in international discussions), meant to serve as one of numerous backup vessels for him due to the inevitable Psycho Power-induced burnout of his body. Also a case of mix and match girl, given how she's basically an identical clone of the kidnapped Russian girl named Decapre, with some Bison thrown in for maximum Psycho Power containing capability.
  • Starfield: Hadrian Sanon is the clone daughter of an executed war criminal, and is worried that her father's misdeeds will be used against her. In the conversation where we learn all of this you can reassure her that she is not her father; and when asked how an opposite sex clone is even possible, she will reply "A lot of gene editing."
  • Super Robot Wars:
    • Ingram Prisken and Viletta Vadim were the male and female options for the protagonist of Super Hero Sakusen. The Alpha and Original Generation games re-envision them as this trope, with Viletta being a female clone of Ingram who wouldn't be subjected to the same mind control that he was under.
    • Kazuma Ardygun has a female clone named Aria Advance. Unlike most examples, she's not a genetic clone, but rather a digital being based off Kazuma's data.
  • In Xenosaga URTV #668, named Citrine is the opposite sex clone of Dimitri Yuriev, as were all of the female variant URTVs.

    Visual Novels 
  • Fate Series: A weird one. In real life Arthurian legend, Mordred is the illegitimate son of King Arthur, made through the intervention of Morgan le Fey (exactly what she did varies depending on the legend). In Fate/stay night, one of the first major reveals is that King Arthur is actually female. Many fans assumed that Mordred would therefore be an Opposite-Sex Clone. In Fate/Apocrypha, we find out that Mordred is indeed an Opposite-Sex Clone... except she's still female. Specifically, Artoria was temporarily transformed into a pseudo-male by Merlin, and Artoria's sister Morgan le Fey used the opportunity to get a DNA sample. She then used that to grow a homunculus of the opposite gender, meaning Mordred came out female. Word of God explained some of this before Apocrypha came out.
  • Arcueid of Tsukihime is more or less a female clone of Crimson Moon Brunestud, the Ultimate Life Form of the Moon and the original template of all Nasuverse vampires. She wasn't intentionally created as such, but as the most powerful True Ancestor to have ever existed, she is, per Nasuverse logic (that copies are always inferior to their originals), the closest it gets to a being a carbon copy of the original vampire, Crimson Moon (who was a guy).
  • Majikoi! Love Me Seriously! has Yoshitsune and Benkei, as per their namesakes, are the female clones of the famous historical figures. Seiso is likely this as well, though it's not yet revealed who she's a clone of.

  • El Goonish Shive had protagonist Elliot using an ancient magical artifact to try to undo a Magitek Gender Bender, inadvertently creating Ellen in the process. She was "born" with a perfect copy of Elliot's memories and personality (though she says the memories feel more like stuff she learned, rather than experiences), but her initial Clone Angst and subsequent (successful) attempts to establish her own identity led to Divergent Character Evolution, so she isn't a simple Distaff Counterpart. People calling her a clone (before getting to know her) is a huge Berserk Button. More than a few scenes make it clear that the classic sex partner idea seriously squicks both of them, since they genuinely care about each other like any two siblings would. Elliot in particular has gone on record saying that his first thought when he saw Ellen mid-freakout was "She's family, help her.". Furthermore, since Ellen was split off by the Dewitchery Diamond, Elliot can be considered Ellen's father and (since this is El Goonish Shive and a Gender Bender was inevitably involved) her mother as well. Unfortunately, all of this (plus Elliot's Chronic Hero Syndrome and Ellen's initial Clone Angst) causes him to treat her like a little sister, which tends to annoy her no end.
    • This potentially may get even more complicated, now that Magus (a Alternate Universe version of Ellen who had used Gender Bender magic in his home worldnote  before getting trapped in the EGS universe in a ghost-like state) is now walking around in a a male Dewitchery Diamond duplicate of Elliot's body. For now, Magus is avoiding the other two, but it is likely that he will re-appear eventually.
  • The community-driven interactive fiction MS Paint Adventures: Problem Sleuth introduces a trio of detectives: Problem Sleuth, Ace Dick, and Pickle Inspector ("pickle" in this context is meant to connote "problem"), who, through spirit quests, are psychically linked with female counterparts of themselves, whom they eventually meet in person and are instantly attracted to. Problem Sleuth gets Hysterical Dame, Pickle Inspector gets Nervous Broad, and Ace Dick, lacking the imagination to think of a female counterpart, simply becomes linked to another male version of himself (albeit one who owns a blonde wig).
  • In Dragon Tails, when Norman the squirrel orders a clone of himself, he marked the sex box with an F (for "Fine the way it is") and got a female clone. The clone is also a child, since this was done with genetics.
    • They were also really drunk while designing her genetic pattern, so they made her glow-in-the-dark as well.
  • The Inexplicable Adventures of Bob!: While trying to manipulate Galatea, Riboflavin shapeshifts into his idea of what a male of her species would look like. Unfortunately, she doesn't actually have a species, and her reaction is, "Oh my G...! A sex-swapped version of my own face? I'll have nightmares for a week!" He then disguises himself as a handsome human male, and gets a much more favorable reaction from her.
  • Not an example, but in Dumbing of Age, Sarah refers to Joyce's nearly-identical older brother actually sister Joshua as this.
  • In I Don't Want This Kind of Hero, Tracy is this to Baek Morae, created by a group of scientists in an attempt to duplicate the latter's power of purification. Baek Morae, on his part, considers her existence disgraceful and so tries to kill her when they meet in the present.
  • Holy Bibble portrays Eve as this to Adam, since she is created from his rib. Due to the comic's simplistic art style, this is primarily shown by her having a similar curly forelock to him, as well as the same skin and hair colors.
  • Subverted in Skin Horse- when the characters travel to an alternate dimension, Tip discovers that this universe's version of him is a woman- but eventually they realize that although they were born at the same time from the same parents, they're no more genetically related than a different brother and sister.

    Web Original 
  • In The Guild Bladezz' little sister looks even more like him than you'd expect (the androgynous clothes probably help). This isn't to put her down, if anything it makes Bladezz retro-actively prettier.
  • As a corollary to Rule 34, Rule 63 (it would have been Rule 36, but it's reversed, get it?) says for every male character, someone has made a female version of that character, and vice versa.
    • Quoth many an anonymous users: "It's not sex; it's masturbation!"
  • The web-toon series Bonus Stage featured a female clone of main character Phil Argus as a gag character, once as a "perfect girlfriend", the next as a "cheap ploy for additional viewership" (applified by bunny ears and fox ears (presumably to appeal to a wider spectrum of viewers).
  • A variant from the Whateley Universe: In "The Second Book of Jobe", kleptomaniac devisor Belphegor ends up downloading a copy of his own personality into a cloned female drow body based on Jobe's "drow formula" and DNA. Hilarity quite naturally ensues, though the overall awkwardness of the situation (and not just because campus security shows up right the next moment) isn't neglected — for one, both Belphegor and Jobe find themselves promptly declared "Belphoebe"'s parents of record, and there's every reason to believe that she's here to stay because there's in-universe evidence that she's managed to dodge the Clone Degeneration bullet...

    Western Animation 
  • Bionic Six: Dr. Scarab's attempt to create a female companion resulted in this. Later, his female clone created opposite sex clones of his henchmen.
  • Danielle "Dani" Phantom in Danny Phantom. She and Danny continue to call each other "cousins" even after she reveals the truth about what she is.
  • DuckTales (2017): The finale shows Webby is some kind of artificial daughter to Scrooge McDuck, which Bradford made because retrieving an Artifact of Doom required a direct descendant of the latter. She's not quite called a "clone", or identical-looking, but no mention is made of adding any other person's DNA. May and June are also genetically Scrooge's daughters, although they were actually made by cloning Webby via magic. Scrooge, for his part, after his initial shock at being called Webby's dad, is elated to find out they're biologically related.
  • In a Valentines episode of House of Mouse, Ludwig Von Drake deduces that the perfect partner for someone would be an Opposite Sex Clone. The two can't stand each other, and she breaks up with himself.
  • In Infinity Train, it's revealed that Hazel, a six-year-old girl is a failed clone of Alrick, Amelia's deceased husband.
  • Johnny Test has at least three female doppelgangers of Johnny. Princess Maribel is by far the most exact and doesn't get an upgrade in hairstyle or even a clothing change aside from a little lipstick. Sissy is the second and Joni West is the last.
  • The Powerpuff Girls (1998): The Rowdyruff Boys, in a twisted-Evil Counterpart way. They aren't so much clones as bargain-basement knockoffs, made when Mojo Jojo imitated the Powerpuffs' creation using more "manly" ingredients. Despite the resemblance to their counterparts, no one treats them as genetically related. The girls defeat the boys by exploiting their disgust for romantic interest without any sort of incestuous implications.
  • Star Wars: The Bad Batch has introduced a single female clone of the very masculine Jango Fett: Omega, who is not under the control of Order 66 and has joined the Bad Batch. The season two finale introduced another female clone in Dr. Emerie Karr who works for the Empire.
  • Transformers: Animated:
  • X-23, a female clone of Wolverine, and an eventual Canon Immigrant from X-Men: Evolution to the comics. See the entry under Comic Books for more detail.

Alternative Title(s): Opposite Gender Clone