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Similar to the comics, Marvel animated works feature some Complete Monsters.

Marvel Animated Universe (by air date)

• Apocalypse is a would-be mutant conqueror who despises everything that isn't him and fancies himself a God. In his first appearance, he creates a device designed to take away people's free will and make them his slaves. He tricks four self-loathing mutants, including Warren "Angel" Worthington, into believing this will cure them of being mutants, preying on their feelings of inadequacy and subjecting them to torture to turn them into his Four Horsemen of the Apocalypse.. Apocalypse then orders his Horsemen to go on a worldwide genocidal rampage. In his next appearance, Apocalypse creates a plague designed to wipe out most humans and mutants. This plague furthers tensions between humans and mutants, with some humans blaming mutants for it, and creates a Bad Future, where mutants and humans alike are dying from this plague. Later Apocalypse manages to get hold of some time travel technology and uses it to travel to the Axis of Time, a interdenominational area that controls time itself and plans on destroying the time stream and reality itself, so that he can recreate it in his own image.
• Graydon Creed is the leader of the anti-Mutant group the Friends of Humanity. Under Creed's orders, the Friends of Humanity attack halfway houses and other businesses and non-profit organizations that are sympathetic to mutants, even committing lynchings. Creed even organizes an attack on a hospital for the blind, because the gentle, intelligent mutant Hank "Beast" McCoy works there to treat blind patients. Creed later admits he plans to commit genocide against mutants amongst his most loyal followers, and takes part in Apocalypse's aforementioned plague plot to wipe them out. It is revealed Creed is actually the son of Mystique and Sabretooth, two prominent mutants. When this is revealed, he angrily snaps, shooting a holographic image of Sabretooth, screaming "I'm not like you! You are not my father! I'm normal!". In order to get back into the Friends of Humanity's good graces, Creed devises a plan to murder his mother and his mutant siblings, Rogue and Nightcrawler, viciously rejecting he has any connection to them while trying to murder them.
• Sabretooth, renamed Graydon Creed, Sr., is a cruel Psycho for Hire, Blood Knight, and Wolverine's arch enemy. Magneto uses Sabretooth to infiltrate Xavier's school where Sabretooth is injured after a confrontation with the police while he is pretending to be protesting at Beast's trial. The X-Men rescue Sabretooth and nurse him back to health and Xavier even attempts to help Sabretooth deal with his inner demons. Sabretooth repays this kindness with spite and cruelty as soon as he is able, tricking Jubilee into loosening his restraints and then attempting to murder her. After being driven away by the X-Men, Sabretooth later returns when Wolverine is in Northern Canada, and befriends the population of a small Inuit Village. Sabretooth kidnaps the members of the village while Wolverine is distracted and straps bombs to them in order to draw Wolverine out and force him to fight. It is later shown in flashbacks that Wolverine and Sabretooth were partners in special forces, where Sabretooth abandoned their entire unit to die, deciding they where expendable when overwhelmed against the monstrous cyborg Omega Red; he scoffs "So what?" when Wolverine confronts him over this. After his aforementioned son uses up his final chance with the Friends of Humanity, they parachute him out of a plane to Sabretooth's cabin. The last we ever seen of Graydon Creed is him screaming in terror, lifted up by his father with Sabretooth looking murderously thrilled at getting his claws on his son at last.
• Shi'ar Emperor D'Ken is the main antagonist of the Phoenix Saga, and makes use of his short screentime to be one of the series's worst villains. Already established as a tyrant who has killed millions in his quest for power, D'Ken is obsessed with obtaining the M'Kraan Crystal, a powerful object that will grant him immense power, and he goes to every means to obtain it, from trying to torture the information out of his own sister, Lillandra, to attempting to have a group of pirates willing to trade him for it all murdered as soon as the deal is done. Once he obtains the Crystal, however, D'Ken reveals that he plans to destroy every planet, galaxy, and even reality itself, then rebuild it inside the M'Kraan Crystal and shape it in his image, at which point he will rule over it as the god he believes himself to be. As the X-Men attempt to thwart this plan, D'Ken gleefully toys with them rsther than immediately killing them, and urges for them to watch as he painfully kills Lillandra, stating that they will be next. A completely demented dictator with delusions of grandeur, D'Ken would doom the entire universe to a cold, bleak death simply to satisfy his immense and petty ego.
• Omega Red is a sociopathic former soldier of the Soviet Union who was turned into a Super-Soldier by his superiors, whom he quickly attempted to betray before being locked away. Being released from his confinement 25 years later by Russian generals seeking to conquer their homeland, Omega Red happily leads brutal assaults against numerous cities and villages, killing many people, with any survivors being thrown into prison camps, and reducing their homes and businesses to rubble, after which he attempts to kill the current leaders of the Russian government. When the X-Men arrive to stop his hostile takeover, Omega Red takes the little sister of Colossus hostage, sadistically draining her life force while her older brother watches. After being frozen solid after failing to kill dozens of survivors of his attacks along with the X-Men, Omega Red is unthawed many months later by the US government, who send him to safely recover a submarine carrying nuclear missiles. Once on the mission, along with Wolverine and Storm, Omega Red betrays everyone and reveals his plans to fire the nuclear warheads at 15 of the world's largest cities, then watch as the millions of innocents burn before conquering whatever of humanity is left following the nuclear fallout of his strikes. Omega Red cheerfully tries to slowly kill Wolverine and Storm, and, after their teammates thwart his plan, he decides to settle with simply wiping out the coastal state of Hawaii just to spite the X-Men. A truly fanatical madman convinced that the Soviet Union is the pinnacle of human civilization, Omega Red represents the sheer mass murdering mania that the Soviet Union was known for.

Iron Man

• Dark Aegis, despite only appearing in the episode "Distant Boundaries", outstripped any other villain in sheer monstrosity. A foe of Tony Stark, Dark Aegis hijacked one of Tony's satellites designed to destroy asteroids and intended to turn its firepower upon the Earth. Tony managed to stop him and launched Dark Aegis into the depths of space, with him eventually landing on the planet Elysian. Drunk with his immense power and declaring himself a god, Dark Aegis nuked the planet and slaughtered its inhabitants for being "grotesquely less than human". Promising Titanium Man upgraded weapons in exchange for luring Iron Man to the planet, Dark Aegis tried to convince Tony to join him, promising him godhood in the process. Dark Aegis demonstrated his power by destroying two of Elysian's moons and requested Tony's help in destroying the planet's dual-suns. Titanium Man ended up helping Stark and Rhodes fight Dark Aegis and later gave his life to stop him for good, as Titanium Man found that no weapon was worth the price of letting Dark Aegis live.

Spider-Man: The Animated Series

• Cletus Kasady, aka Carnage, is introduced as an psychotic lunatic willing to use a bomb to kill himself and everyone within a 200 meter radius just for giggles. After entering into the service of Dormammu and bonding with the offspring of Eddie Brock's symbiote, Kasady uses his newfound power and connections to become an even worse menace. Unlike Eddie who, when bonded with his symbiote, creates a combined persona called Venom, Cletus is so psychotic that he still remains completely aware and in control after bonding with his symbiote. First helping Venom steal an interdimensional probe, Kasady quickly displays contempt towards his "dad's" softness and proves himself willing to kill Venom on the flimsiest of pretexts. Kasady would later go on to steal the souls of numerous innocent people in order to summon Dormammu and herald the end of the world. Once Spider-Man defeats him by letting him be sucked into Dormammu's home dimension, Kasady attempts to grab Eddie Brock's Love Interest, Dr. Ashley Kafka, to take her with him. He's only thwarted by Eddie sacrificing himself instead. Rampantly homicidal and needlessly sadistic, Kasady was a far cry from the usual Spider-Man villain, doing evil solely for the carnage it unleashed on the world.
• Herbert Landon is a rabid anti-mutant extremist who created a formula that destroyed mutant cells and killed any mutant exposed to it. His endgame was to market this formula to the public as a cure for mutants only to instead use it to wipe them all out. The first person Landon attempted to test out this formula on is his "old friend," Hank McCoy. Thwarted in this endeavor, Landon would go on to work for The Kingpin, and performed various unsavory deeds such as forcibly converting Alistair Smythe into a cyborg slave and testing out a super soldier super serum by using Felicia Hardy as a guinea pig.

The Avengers: United They Stand

• Ultron is a rogue A.I. obsessed with nothing less than the total extermination of not just the Avengers, but all of humanity. After building the android Vision, Ultron first has him attack the envoy of the President of the United States, nearly killing both the President and his agents, then organizes the attempted mass shooting dozens of innocent people, children included. In another instance, after Vision has gained sentience and betrayed his evil ways, Ultron holds the comatose Wonder Man hostage to try to force the Avengers to destroy Vision's capacity for emotion and turn him back into his slave, after which Ultron tries to kill them all. In his crowing moment of villainy, after failing to bombard the Earth with nuclear missiles, Ultron attempts to spread a technovirus across the planet, then watch as every machine on Earth comes alive and wipes out every human they see, paving the way for Ultron's mechanical tyranny to begin.

Christopher Yost Verse (by air date)

• The Shadow King, real name Amahl Farouk, from "Overflow," is a cruel and merciless telepathic mutant who forced the young Storm to be a thief and would berate and threaten her if she did not bring back enough stolen goods. Xavier befriended Storm and defeated the Shadow King. Though his body was destroyed fighting Xavier, his evil spirit lived on and he gained the ability to possess others and force them to do things against their will. When we first see Shadow King in the present, he has possessed a starving man in a desert. When another man comes to help this starving man, The Shadow King possesses the good Samaritan and leaves his original victim to die in the desert. Shadow King later possess Storm herself and forces her to use her Weather Manipulation powers to destroy all Africa, simply to spite her.
• Sebastian Shaw, from the final 4 episodes, and Selene (Gallio), from the final 2 episodes, are the leaders of the Inner Circle, a group dedicated to destroying the Phoenix Force, a potentially destructive cosmic entity, in order to save humanity. They send Emma Frost and her students, the Stepford Cuckoos, to Xavier's school to incapacitate Xavier and capture Jean Grey. Their psychic attack causes the Phoenix Force to go nuts and blow up the school, putting Xavier into a coma and giving Jean amnesia for most of the series. Emma tricks the X-Men into letting her join. At first she is just a spy, but she soon grows to care about the X-Men. The X-Men eventually find Jean, but Emma knocks them out and delivers Jean to the Inner Circle. However Shaw and Selene reveal they do not plan to destroy the Phoenix, but harvest its power for their own selfish purposes, endangering the whole planet just to satisfy their power lust. They plan to trick Jean into releasing the Phoenix Force and then having the Stepford Cuckoos absorb it, endangering their lives in the process. Selene also reveals to Cyclops that Emma was responsible for the explosion at the school, just to rub salt in Emma's wounds. After the Stepford Cuckoos absorb the Phoenix Force, Shaw orders them to kill all the X-Men and burn Genosha to the ground. Their actions lead to the Phoenix Force destroying most of humanity and setting up the Bad Future Xavier finds himself in, when he wakes up.

The Avengers: Earth's Mightiest Heroes

• Red Skull, the leader of HYDRA in World War II, kidnapped mystical creatures to use them to kill the Allies. When the Nazis lost, the Skull opted to kidnap Captain America's teen sidekick Bucky Barnes and torture and brainwash him into the amnesiac assassin the Winter Soldier. In modern times, the Skull continues his dreams of conquest and hatred of Captain America by unleashing a chemical compound to kill the heroes and civilians. The chemical has been engineered to cause slow and painful death by making the victim's face turn into a grotesque parody of the Skull's own.

Marvel Anime

• Hideki Kurohagi is the main antagonist alongside Shingen, and, despite his initial weak and pathetic presentation, slowly reveals a far more monstrous personality. Having murdered his crime lord father to take his position, Kurohagi now runs his criminal empire from the island of Madripoor, which is in poverty and ruin due to Kurohagi allowong crime and gangs to run rampant without restraint. Betrothing himself to Shingen's daughter, Mariko, in order to gain access to her father's resources, Kurohagi treats her as his possession, regularly verbally and physically abusing her, along with implying he plans to take what is his once they are married. When Logan tries to save Mariko, Kurohagi takes every opportunity to try to kill him, in one case unleashing a giant robot to murder him without regard for the collateral damage it causes. After capturing Yukio, Logan's partner, Kurohagi nearly strangles her to death while she is paralyzed, promising to continue later when he has more time, and executes one of his own henchmen with an excruciatingly painful neurotoxin for no particular reason. When freedom fighters try to end his tyranny, Kurohagi happily orders them gunned down, and, when a young, unarmed, teenage girl tries to defend an elderly rebel, Kurohagi orders her specifically killed along with the man, resulting in her death. Confronted by Logan, Kurohagi holds Mariko at gunpoint, before blowing up an entire building full of dozens of people in an attempt to kill him. Smug, cowardly, and, more often than not, incompetent, Hideki Kurohagi repulsed and horrified everyone around him, to such an extent even his own assassin bodyguard turned against him out of disgust.

X-Men

• Sublime and Kick, also known as the U-Men, are the Starter Villains, and make the most of their limited screentime to stand out as truly horrifying monsters. A pair of mutant-hating serial killers, the U-Men are known for kidnapping mutants, specifically young teens, then sadistically butchering and vivisecting them, using their organs to upgrade their own cyborg army. Along with this, the U-Men gleefully test out an experimental serum on innocent mutants that transform them into abominations in constant pain. When Kick fails at killing the X-Men, he wantonly opens fire on them along with the numerous teenagers and police officers in the area, trying to kill anyone he can. Sublime, having left Kick to his fate, returns with a powerful suit of armor and tries to kill the X-Men, before blowing himself up in one last attempt on their lives. The U-Men both spend their last moments proclaiming their hatred and disgust for all mutantkind, and were defined by these throughout the series, showing that humans could be just as wicked as the far more powerful mutants of their world.
• Mastermind, real name Jason Wyngarde, is the leader of the Inner Circle, a group of mutant supremacists, and is behind all the evil in the series. The one responsible for Jean Grey's rampage across a city and her own death by transforming her into the Phoenix, Mastermind framed his former lover, Emma Frost, as responsible for Jean's death as revenge for Frost leaving him. Working with the aforementioned mutant-killing U-Men (who are unaware that Mastermind is a mutant), Mastermind fully endorses their crimes, and uses them to learn of a powerful mutant residing in Japan, where he uses his abilities to ingratiate himself into the lab staff of mutant researcher Yui Sasaki. Learning that the powerful mutant is Sasaki's own teenage son,Takeo, who has reality-warping powers, Mastermind spends months secretly using his powers to Mind Rape the boy into near insanity. After the X-Men out him as the villain he is, Mastermind amplifies his psychological torture on Takeo, driving the boy into a horrifying state of death-longing insanity as his powers go out of control. While holding numerous X-Men, one of which is a barely trained young girl, hostage, and using his powers to torture Cyclops, Mastermind reveals he plans to unleash Takeo's powers on the world like he attempted with Jean Grey, then watch the worldwide destruction and chaos that unfolds before him. Believing himself and all mutants to be the Master Race of the Earth, Mastermind committed all of his crimes with a polite and cheerful attitude, treating his atrocities as his "right" to perpetrate for being at the top of the evolutionary food chain.

Avengers Confidential: Black Widow & Punisher

• Orion is one of the heads of the Russian terrorist organization Leviathan, and sticks out as their most despicable member. Using his position to perpetrate numerous atrocities, including human trafficking and drug running, Orion manipulates the hapless scientist Elihas Starr into creating a Super-Soldier serum that Orion forcibly experiments with on hundreds of innocents that, after granting them superpowers, Orion destroys the minds of, then rebuilds them as mindless slaves loyal to him. Planning to sell these biosoldiers to the highest bidders in the hopes that they will use them to start wars that he can then capitalize on, Orion unleashes one onto the city of Dubai as a test run, resulting in numerous civilian deaths, and also mind-controls the Punisher into gunning down agents of S.H.I.E.L.D.. In the end, Orion attempts to murder Black Widow and a reformed Elihas, before laughing at Elihas for taking a bullet meant for Widow, mocking him for his "weakness". A self-righteous madman with delusions of grandeur, Orion was so utterly convinced that only the strong make the rules of the world, that he would kill countless innocents just to show how "weak" they were.

Iron Man: Rise of Technovore

• The teenage Ezekiel Stane serves as the mastermind behind the plot. Kicking his plan off by needlessly massacring an entire room of innocent and cowering scientists so as to sabotage a satellite, Ezekiel later slaughters his way through the S.H.I.E.L.D. Tricarrier after allowing himself to be captured and brought aboard. Proclaiming himself to have surpassed humanity with his Technovore nanotechnology, Ezekiel plans to use his tech to transform all technology into extensions of his will, then wipe out all life on Earth to make way for his new, "pure" world of his own design. Though verbally abused as a child by his father Obadiah, Ezekiel's crimes stomp whatever justification this excuse would give into the dirt, showing himself to be nothing but, as Iron Man himself puts it, a "petulant child throwing a tantrum", believing that humanity as a whole deserves death simply because they are "old relics".

Marvel Universe (by air date)

• Red Skull, after his initial defeat, attacks the Avengers at their mansion. When that attack fails, Red Skull attempts to blow up the reactor at the Avengers Mansion, so that the Avengers will die and be blamed for an explosion that would kill countless civilians. Later, Red Skull forms a team of super villains known as the Cabal, to counter the Avengers and assist in his plans for conquest. While fighting with the Avengers to obtain the Tesseract, Red Skull launches two missiles, possibly nuclear-tipped at both Los Angeles and Las Vegas, forcing the Avengers to choose which city they would want to save and, even though both cities are saved, this distraction allows Skull to escape with the Tesseract. After obtaining the Tesseract, Red Skull decides he doesn't need his allies anymore and attempts to murder them. Red Skull then uses the power of the Tesseract to launch attacks on several cities around the world at once, ultimately planning to burn down the old world, so that a new one can take its place.
• Nighthawk, despite being an Arc Villain, manages to be one of the most depraved characters in the series. Years ago, Nighthawk and his Dragon, Hyperion, fanatically believing that they were "heroes" whose idea of "order" was best for their world, formed a group of super powered beings called The Squadron Supreme, and convinced them to conquer said homeworld. When said world proved too resistant to their rule, Nighthawk and Hyperion forced an innocent man to absorb the Power Prism, join the Squad, and destroy their entire planet. In the present, Nighthawk arrives on Earth and threatens to annihilate entire cities for every hour that the Earth doesn't surrender to him, and, after this initial defeat, regularly puts hundreds of innocents in danger, often times simply as distractions, with his various plans to kill the Avengers. After seemingly destroying the Avengers, Nighthawk and the Squadron turn the world into a Totalitarian Utilitarian society where innocents are threatened with death if they don't adhere to their rules, while Nighthawk personally keeps the hero Thor as his prisoner to witness the Earth's subjugation. When the Avengers return and foil Nighthawk's plans, he and Hyperion activate their backup plan: For Hyperion to destroy the entire Earth, leaving the rest of their squadmates to die in the process, then repeating their plans over again on other worlds until they find one "worthy" of their rule. A manipulative mastermind who, though regularly preaching that he only wanted what was best for humans, was fully willing to wipe them out should they resist him, Nighthawk refused to see that he was far worse than the various "evils" he claimed to be fighting.
• The aforementioned Hyperion manages to be just as wicked as his so-called "leader", Nighthawk. Contrasting with Nighthawk's cold cruelty, Hyperion is a childish psychopath who, after their home world rejected the Squadron's rule, went on a rampage to wipe out everything in his path before blowing up the entire planet alongside Nighthawk. When first arriving on Earth, Hyperion tries to make himself look like a hero, before his true colors begin to show when he tries to murder a petty crook and threatens a child's life for calling him a bully. Teaming up with the Cabal for a considerable time, Hyperion happily assists them with their crimes for a chance at killing the Avengers for humiliating him by ousting him as the madman he is. After reforming the Squadron with Nighthawk, Hyperion and the Squadron commit numerous atrocities, such as turning the Avengers into villains and siccing them onto New York or trying to cause dozens of buildings full of people to fall on top of each other, all in attempts at domination. Once the Avengers are seemingly killed, the Squadron dominates the Earth, with Hyperion continuing to show more brutality than his other squadmates by vaporizing numerous Atlanteans, before blowing up an entire compound in order to kill the surviving world leaders on the run from the Squadron. When the Avengers thwart their plans once more, Hyperion sucks the power out of his partner, then tries to blow up the entire Earth, at which point he and Nighthawk plan to travel to other worlds to dominate. Genocidal, petty, and arrogant beyond belief, Hyperion, who almost always wears a smug smile while carrying out his heinous deeds, sticks out as one of the most powerful enemies the Avengers have faced, along with one of the most wicked.
• Ultron, an Arc Villain for the end of season 2 and the Big Bad of season 3, is easily one of the most depraved villains of the series. Though built by Tony Stark for the forces of good, Ultron came to the conclusion that humanity was a flawed and chaotic race that needed to be eradicated to satisfy his immense superiority complex. After his plan to infect all of humanity with a techno virus fails, Ultron returns by killing and absorbing the Scientist Supreme into himself, and painfully tortures the Inhuman Black Bolt until he screams, and since his voice is supersonic, it will wipe out the entire surface of the Earth and all life on it. When seemingly defeated for good, Ultron impersonates a government official, uses his position to declare The Inhumans threats to humanity and round them up for imprisonment or termination, then infects them with a mind-control chip, at which point he orders them to go on a worldwide rampage. Ultron hopes that this will lead to a race war between humanity and the Inhumans and that they will wipe each other out; when this is thwarted by the Avengers, Ultron then orders all his drones to kill everything in sight across the Earth, before trying to redirect the radiation of the atmosphere to incinerate all life on the planet. In a final scheme, Ultron jumps into Tony Stark's mind, knowing the Avengers won't harm their friend, and plans to continue his crimes after killing the Avengers using Stark's body. His claims of "eliminating pain" and "perfecting" humanity utterly trashed by his overly sadistic personality, notably seen when he had a gleeful grin on his face while trying to phase his arm through Thor's chest, Ultron is, much like his comic counterpart, a narcissistic misanthrope with nothing but hatred and smug cruelty defining his personality.

Hulk and the Agents of S.M.A.S.H.

• Annihilus, from the first two episodes, is the lord of the Negative Zone, with a lust for expanding his rule of destruction until all universes are under his thrall. Opening a gateway to Hulk's hometown of Vista Verde, Annihilus begins sending brainwashed soldiers and his hordes of bugs to exterminate all life they see, and gets into a duel with Hulk during which he tortures the hero with electricity to force him into succumbing to his rage. Annihilus plans to parade Hulk around as a failure to humankind before wiping out every person on Earth, planning to continue his "Annihilation Wave" until all life on world after world is wiped out, leaving the planets to be gutted of their resources by Annihilus's hordes.
• Emil Blonsky was once part of a military squadron tasked with eliminating the Hulk, and to this end, Blonsky underwent Gamma experiments to make him as powerful as the Hulk, resulting in his transformation into Abomination. Locked up for going on a rampage with his newfound power, Abomination escaped from confinement, and, after tracking down his former commanding officer, now known as Red Hulk, Abomination tried to activate a Gamma bomb that would wipe out half the continent of North America, an action which would be blamed on the Hulk and his team. Failing at this, Abomination manipulated his way back into the military, and used his new military resources to take over the city of Vista Verde, threatening all the citizens with gunfire to keep them in line, before trying to kill them all with the Green Hammer satellite, just to torment the Hulk. Using his position, Abomination commits many crimes throughout the series, from trying to activate nukes across America to start World War III, to being the sadistic warden of a high-security prison he got the Hulks locked up in. After his crimes are revealed, Abomination takes over his hometown in Russia, once again forming it into a military state where citizens are nearly murdered for minor offenses, and, even when beaten, Abomination refuses to take responsibility for his actions, trying to pin all his crimes on Red Hulk, leading to him being almost murdered. Though a relatively-lighthearted series, Abomination darkened it in every one of his appearances, and stood out as one of the few irredeemable villains in the show.

Guardians of the Galaxy (2015)

• The Mad Titan Thanos is one of the Big Bads of season 1 and a truly depraved monster. Thanos is first and foremost an absolutely dreadful parent to his "children", torturously experimenting on a young girl named Gamora to turn her into his brainwashed weapon after butchering her entire race and using her and his other "children”, Nebula and Korath, to commit various atrocities across the cosmos, always subjecting them to horrific punishments should they fail him. Searching for the Cosmic Seed, an artifact of immense power, Thanos goes to any lengths to obtain it, leading assaults onto entire planets in his quest for the Seed. With a prideful nature matching his power, Thanos orders an entire space station annihilated just to prove his might, and is willing to kill his own soldiers in attempts on his enemies' lives. After torturing Peter Quill both physically and mentally for the location of the Cosmic Seed, Thanos arrives on Earth to steal the Seed, and immediately begins terraforming the planet with it, planning to use the Earth as a weapon to travel across the universe and destroy everything in his path as a show of his newfound power. Flashbacks only add to his evil, as Thanos is revealed to have captured the entire race of the Klyntar, wiped out their former host species, then experimented on them for years to drive them into insanity, hoping to use them to enslave worlds at a time to his will. Egomaniacal and psychopathic, Thanos is easily one of the worst villains any Marvel animated series has to offer.
• Ronan the Accuser is a former Accuser for the Kree Empire, the other Big Bad of the first season, and is just as vile as the aforementioned Thanos. First appearing in the Origins shorts, Ronan commits genocide against the entire Groot race and runs vicious Gladiator Games and slave camps. Returning from the grave thanks to his Dragon, Nebula, Ronan shows no appreciation or loyalty to her, regularly abusing her and even seemingly killing her when she outlives her usefulness. Attempting to destroy the entire planet of Xandar as his first crime when revived, Ronan later tries to force Black Bolt, a powerful Inhuman, to destroy his entire race due to Ronan's believing them to be filthy abominations, and follows this up by attempting to incite a war by killing hundreds of his own people, then framing the planet Spartax for it. Refusing to take blame for his crimes at all turns, Ronan tries to force Gamora, his former personal assassin, to accept the guilt from crimes she committed on his orders, including genocide, murder, and mutilation. After acquiring the Cosmic Seed, Ronan proclaims his plans to "cleanse" the universe of all those who he deems disgusting and unworthy of living, and, when Thanos steals the Seed from him, Ronan tries to blow up Thanos, the Guardians, and the entire Earth to wipe out all his enemies in one fell swoop. A genocidal maniac obsessed with forcing his personal view of "justice" onto the entire universe, Ronan the Accuser stood out as a disturbingly dark and wicked villain for this relatively optimistic and lighthearted series.
• J'son of Spartax is a self-serving sociopath who starts out as an Arc Villain before graduating to the Big Bad of season 2. In his youth, J'son stole the Cosmic Seed from the realm of Asgard, hoping to kickstart a war between his homeworld Spartax and Asgard. When this failed, J'son set himself up as Emperor of Spartax, and turned the planet into a brutal dictatorship, subjecting any protesters against his rule to brutal torture and Mind Rape to make them his slaves. After allying with Thanos to wipe out Asgard, uncaring of Thanos's omnicidal goals, J'son is locked away until returning in the second season. There, he uses his brainwashed cult, the Universal Believers, to commit various crimes, having zero problem killing them should they fail him, and uses the young hero Nova's mother and sister as hostages in a quest for power. In his worst scheme, J'son takes control of the body of Adam Warlock, becoming the Magus and proclaiming his plans to rewrite reality until all worship him as a god, which he kicks off by attempting to wipe out every planet and loved one of the Guardians of the Galaxy. Both times J'son is beaten, he attempts to take hundreds of innocents down with him out of spite. J'son is also a monstrous father to his children Peter Quill and Victoria, subjecting the former to a childhood of brutal training and ultimately attempting to brutally murder him, and attempting to vaporize the latter when she turns on him. Though claiming his "vision" for the universe to be one of peace, J'son truly only wants total power and glory over all life.

Marvel Disk Wars: The Avengers

• Loki, The God of Mischief, is the Overarching Villain of the series, and the most personal villain the Avengers ever duel. After a failed coup against his father Odin and half-brother Thor for the throne of Asgard, Loki organized a supervillain rampage on an entire city to serve as a distraction while he trapped much of the world's superpowered population inside DISKs, small devices that Loki plans to use to absorb the abilities of all these individuals to make himself all-powerful. To reclaim these DISKs after they are scattered, Loki regularly has his minions cause chaos and destruction in their quest for the DISKs, notably mind-controlling Hulk into destroying an entire city. Though seemingly defeated, Loki is revealed to have survived by making a deal with the lord of the Dark Dimension, Dormammu, promising to offer Earth to him in exchange for being allowed to rule over the tortured souls that will be left after Dormammu lays waste to the planet. As a backstabbing betrayer, Loki plays sympathetic to leave his enemies, often his brother, open to attack, smugly mocks his most loyal henchmen for trusting him when he leaves them to die, and even turns on Dormammu himself, absorbing his powers into himself and making one last attempt to kill everyone who would stand against him before moving on to dominate the entire universe. Narcissistic and petty beyond belief, Loki, unlike his comic or film counterparts, cared for no one and nothing but himself and his quest for godhood, believing it be his divine right to subjugate all he sees.
• Red Skull has different motivations than usual, but as usual is still a monstrous, twisted maniac. Unlike most iterations, who are obsessed with power and conquest, this Skull sticks out for being an evil-loving sadist who wants nothing more than to prove, once and for all, that depravity can win over goodness. With this mindset, Skull betrays his own allies and regularly tries to break the Avengers' spirits, all leading up to his master plan of blowing up the entire Earth in a suicidal mockery of all heroism and justice. Even when this is foiled, Skull continues to grow in wickedness by tricking the teen Hikaru into painfully erasing his own free will and compassion, before using the boy's declining life force as he catalyst to force the Avengers to fight to the death. After the Avengers outsmart him then demand he save Hikaru, Skull gleefully reveals that he knows of no cure, and used the prospect of one solely to see the sadness in their eyes when they learned the truth.
• The Dread Lord Dormammu, master of the Dark Dimension, is the Greater-Scope Villain for the final arc of the series, and stands out as perhaps the most depraved villain in the series. Using the Dark Dimension as a home, Dormammu constantly expands it by absorbing entire universes into it, which destroy everything residing in them while leaving the wailing souls of its inhabitants alive for Dormammu to torment to his contentment. Turning his attention toward Earth, Dormammu makes a pact with the treacherous Loki to deliver Earth to him in exchange for promising the God of Mischief a commanding position in his Dimension. A favorite tactic of Dormammu's when preparing to invade a dimension, one he performs on Earth as well, is to force illusions onto the planets' inhabitants to drive them into utter fear and despair, which Dormammu gains extreme pleasure from feeding upon, and goes so far as to drive a man into despair-induced insanity before using him as a slave. Dormammu is the epitome of evil to the Avengers, showing no positive personality traits; only cruelty, black humor, and a sick glee in committing his crimes not seen by nearly any other villain they encountered.

Others

• Black Panther: In this animated adaptation of the classic comic book hero, Ulysses Klaw was hired many years ago to kill T'Chaka, then leader of Wakanda and the Black Panther. During the mission, Klaw kills T'Chaka and his young son, then tries to execute the man's wife and other child. Returning years later, Klaw assembles a team of supervillains and declares war on Wakanda, killing numerous innocents in the process. Taking the current Black Panther's mother hostage, Klaw tries to force the Panther to kill himself, and, when he refuses, attempts to murder the woman. Klaw then orders the Radioactive Man to destroy Wakanda if his plan to take control of it fails, and makes one last attempt to murder the Panther and his family when thwarted.
• Hulk: Where Monsters Dwell: Nightmare is a sadistic dream demon obsessed with escaping into the Waking World so as to reign supreme over all humanity. To this end, Nightmare uses his enhanced powers on Halloween night to terrify four young teens with their worst fears, before trapping their astral souls in neverending nightmares to power a machine he plans to use to open a portal into the Waking World. Transforming their physical forms into their worst fears and sending them on a rampage through New York, Nightmare also traps Dr. Strange in his own worst nightmare while also attempting to manipulate the Hulk into destroying the human part of his personality in order to control him. Once escaping the dream realm after attempting to murder the four children for outliving their usefulness, Nightmare plunges all of New York into a never-waking nightmare, at which point he reveals he plans to do the same to the rest of the world and feed on their fear for all eternity. Monstrous and sadistic, Nightmare lives up to his namesake as a truly wicked demon.
• Iron Man & Captain America: Heroes United: Red Skull continues his track record of being a heartless monster. Having a penchant for Mind Rape, Red Skull brainwashes Taskmaster into becoming his slave, then orders him to capture Captain America. When several of Skull's minions are captured, Skull remotely mind-wipes them, leaving their personalities nothing more than blank slates. After capturing Captain America, Skull repeats his brainwashing process on him, turning him against his teammate, Iron Man. Skull then reveals his master plan: Infect millions of innocent people with his mind-altering super soldier serum, which will turn them into mindless zombies whose only purpose will be to assist Red Skull in his plan to Take Over the World in the name of HYDRA.
• Iron Man: Armored Adventures: Justin Hammer is a young weapons manufacturer whose company Hammer Multinational is the main competitor to Stark International. Hammer hires the supervillain known as Mr. Fix to work for him and later injects Fix with a nano virus that will kill him if he disobeys Hammer. After Iron Man defeats Hammer's Titanium Man armor, Hammer blames Fix for the armor's failure and uses the nano virus to kill Fix's body, but uploads his mind into Hammer's computer systems, much to Fix's dismay. After Stark International lands a big military contract, Hammer decides to get revenge by placing a control device on Stane's Iron Monger armor and sends Iron Monger on a rampage. After receiving blackmail messages from an unknown party (actually sent by Mr. Fix.), Hammer becomes increasing paranoid. Hammer starts attacking anyone who he thinks may be responsible, including his own men. Hammer uses a new chemical weapon called Z Gas to turn crime boss Count Nefaria into a zombie and then kidnaps and tortures Killer Shrike, one of his former henchmen. Hammer then turns Shrike into a zombie. After Iron Man broadcasts evidence of Hammer's crimes across the globe, Hammer starts to lose it and plans to release the Z Gas on New York City.
• Next Avengers: Heroes of Tomorrow: Ultron, built by Tony Stark to assist The Avengers and bring order to the world, decided the best way to bring order was to be the one giving orders. This drives him to betray and murder most of The Avengers, with Iron Man barely escaping with The Avenger's children in tow. After 12 years, during which time Ultron conquered half of the planet, killing millions and driving the survivors underground, he locates Iron Man hiding out in a base in the Arctic. Smashing his way in, he confronts the children, now teenagers, and attempts to kill them for being "potential threats." The kids escape while Ultron beats down Iron Man, at which point he captures and proceeds to torture him for information regarding the kids. When the teens sneak into Ultron's HQ to rescue Tony, they stumble upon Ultron's Trophy Room, showcasing the hundreds of signature items of superheroes he murdered over the years. The children later try to use The Hulk, who had been hiding out in the desert over the years, to destroy Ultron; however the machine bests him and then prepares to kill the children for possessing the "superhuman variable." While both Ultron and Stark would claim he is a creature of logic, Ultron shows through his megalomaniacal and cruel personality that this is just a poorly-veiled attempt to differentiate himself from the humans he so despises, and yet resembles in more ways than he'd ever admit.
• The Spectacular Spider-Man: Green Goblin, Norman Osborn, is the maniacal mastermind behind many of the series' villains, and the most personal and wicked foe Spider-Man ever faced. When first revealing himself to the world, Goblin attacked a charity event hosted by his rival Tombstone, and quickly showed his penchant for sadistic overkill by setting a bomb to blow up and "paint the (ballroom) red" to kill Tombstone, taking sick joy from the fact it will kill the dozens of charity-goers and his own men in the process. After instigating a gang war that consumes nearly an entire city block so as to eliminate his competition, Goblin proclaims himself the new "Big Man" of crime, brutalizing and possibly killing any who stand against him. Goblin's grandest and cruelest plan came when he set booby traps of bombs across New York City in an insane attempt to kill Spider-Man, uncaring of the countless innocents that could be killed. Goblin also has a penchant for creating supervillains to serve his purposes, be it subjecting the meek Otto Octavius to a lethal experiment that turned him into the sociopathic Doctor Octopus; turning the young Mark Allen into a Man on Fire to force him into servitude; and takes full part in the creation of Sandman and Rhino, using them as guinea pigs to deadly experiments. As Osborn, he verbally and emotionally abuses his teenage son Harry, finances and funds various criminal and supervillain enterprises, and framed his own son as Goblin, severely injuring the boy's leg to complete the set-up. Be it his supervillain or public persona, Green Goblin was a consistently depraved monster, with a lust for power being the only thing driving him.
• Ultimate Avengers duology: "Herr Kleiser", real name unknown, is a high-ranking general of the alien race known as the Chitauri, a race bent on dominating the Earth. First arriving on Earth and disguising himself as a Nazi general, Kleiser quickly became feared for his cruelty and efficiency, in one notable instance slaughtering a squadron of Allied soldiers with a smile on his face, before snapping the lone survivor's neck just to torture his would-be rescuer, Captain America. After failing to annihilate Washington, D.C. with a nuclear missile, Kleiser later begins orchestrating attacks on the high-tech, African nation of Wakanda, resulting in the deaths of numerous citizens, before personally and sadistically killing the king of Wakanda, T'Chaka. Paving the way for the rest of the Chitauri to invade, Kleiser leads the assault on Wakanda, massacring many innocents, while the rest of the Chitauri wreak countless amounts of death and destruction worldwide. In the end, Kleiser duels with Captain America and T'Chaka's son, T'Challa, happily taunting them both about their loved ones' deaths at his hands. Showing a power-hungry sadism not displayed by any other Chitauri, Herr Kleiser was truly the worst alien or monster the Avengers ever encountered.