A list of actors who have appeared on Hawaii Five-O and related media.
Appeared in Hawaii Five-O (1968–1980):
- Maud Adams: Maria Noble
- Philip Ahn: Lin Mai-Lu/Quon/Attorney General
- Norman Alden: Cameron
- John Anderson: Brigadier General Earl Rigney
- Richard Anderson: Eugene Goodman
- Edward Andrews: Roswell Borden
- Michael Ansara: Piro Manoa
- Lou Antonio: David Harper
- Allan Arbus: Vince Maynard
- Anne Archer: Jane Michaels
- Adam Arkin: Alex Scofield
- R. G. Armstrong: Warden/Captain Wade
- Edward Asner: August March
- August March in Hawaii Five-0
- Tom Atkins: Koko Apaleka
- Lew Ayres: Comm. Reginald Blackwell/Dr. Elias Haig/Governor
- Richard Basehart: Murdock
- Arthur Batanides: Consul
- Barbara Baxley: Elizabeth Rollins/Sadie
- Ned Beatty: Keith Caldwell
- Dirk Benedict: Walter Clyman
- Theodore Bikel: Prof. Erich Stoss
- Raye Birk: Parole Officer
- David Birney: John Richard Carr/Lt. Waldron/John Dillon
- Lloyd Bochner: Israeli Secretary/Colonel Avery/Capt. Roger Newhouse/Walter Gregson
- Earl Boen: Denisovich
- Sorrell Booke: Dr. Sam Berman
- Linwood Boomer: Nick
- Barry Bostwick: Lucas Sandover
- Bruce Boxleitner: Paul Colburn/Kevin Caulder/Cam Faraday
- Guy Boyd: Gary Carter
- Stephen Boyd: Costigan
- Eric Braeden: Djebara/Klaus Marburg/Dr. Paul Farrar
- Ray Buktenica: Clifford Sprague/Billy Grunwald
- Victor Buono: Eric Damien
- Roger C. Carmel: Misha the Bear
- Jack Carter: Harry Foxton
- Jack Cassidy: Morwood
- George Chakiris: Lahani
- Cyd Charisse: Alicia Warren
- Dennis Chun: Officer Wade/Assistant/Attendant
- Sgt. Duke Lukela in Hawaii Five-0
- John Colicos: Mr. Thorncrest/Lorenzo Corman
- Gary Collins: Henry Lockman
- Michael Conrad: Arthur/Kira Johnson
- Jackie Coogan: Frank/Jerry Howe/Horace Sibley
- Jackie Cooper: Dr. Alex Southmore
- Gretchen Corbett: Glynis
- Jeff Corey: Andrew Duncan/Dr. William Hanson
- Hume Cronyn: Lewis Avery Filer
- Cathy Lee Crosby: Dr. Karen Lynch
- Pat Crowley: Dr. Elizabeth Fielding
- Keene Curtis: Professor Dobbs Burke/Vincent Gordon
- Jeff Daniels: Neal Forrester
- Royal Dano: Hody Linquist
- James Darren: Johnny Munroe
- Henry Darrow: Stewart Longworth/Billy Madrid/Johnny Aporta
- Ossie Davis: Ramon Borelle
- John Dehner: Anthony Del Vecchi
- William Devane: Fallon
- Susan Dey: Susan Bradshaw
- George DiCenzo: Yuri Bloch/Professor Alika Kalei/Len Jessup
- David Doyle: Hard Hat
- Patty Duke: Toni
- Sylvia Spencer in Hawaii Five-0
- Charles Durning: Haven
- Marj Dusay: Andrea Claire Dupre/Nicole Wylie
- Buddy Ebsen: Professor Pierce
- Samantha Eggar: Agnes DuBois
- Lisa Eilbacher: Elaine
- Dana Elcar: Dr. Benjamin
- Sam Elliott: Jack Houston
- Stephen Elliott: Enslow
- Erik Estrada: Rono
- Mel Ferrer: Emil Radick/Father Neill
- Meg Foster: Anne Waring/Nina
- Robert Foxworth: Dr. Eric Fowler
- Anne Francis: Alicia Wade
- Charles Frank: Todd Seymour
- Pamela Franklin: Bobbie Jo Bell
- Mary Frann: Jean Holland
- Alan Fudge: Ben Dawson/Piet De Groot/Paul Hamilton/Joe Burdick
- Will Geer: Professor Lochner
- Ron Glass: J. Paul
- Jonathan Goldsmith: Vaughn/George Barker
- Frank Gorshin: Stash
- Harold Gould: Honore Vashon
- Farley Granger: Arnold
- James Gregory: Mike Finney/Jonathan Kaye
- Andy Griffith: Arnold Lovejoy
- George Grizzard: Al Marsh
- Clu Gulager: Arthur Lambert/Jack Gulley
- Moses Gunn: Willy Stone
- Jessica Harper: Sunny Mandell
- Al Harrington: Ben Kokura/Fred Noonan/Ray/Guard Bates/Charlie Cayliss/Toshi
- Mamo Kahiki on Hawaii Five-0
- Richard Hatch: Tommy/Gar/Mike
- Helen Hayes: Aunt Clara Williams
- Pat Hingle: Dr. Grant Ormsbee
- Darby Hinton: James Scott
- Robert Hogan: Martin Rogers
- James Hong: Soong Chien/Eric Ling/Tot Kee/James Watanu
- David Huddleston: Vincent Rhoads
- Tab Hunter: Mel Burgess
- John Ireland: Phil Coleman
- Harvey Jason: Ram Busham
- Peter Jason: Jack Rigney
- L.Q. Jones: Colonel Lew Cardell
- Katherine Justice: Andrea Burdick
- James Karen: Dale Wingfield
- Casey Kasem: Larry Swift/Freddie Dryden
- Sally Kellerman: Eleanor
- Richard Kiley: Sam Patton
- Perry King: Jay Faraday/Nick McDivitt
- Terry Kiser: Augie
- Yaphet Kotto: L Cpl. John T. Auston
- Clyde Kusatsu: Jerry Quan
- Judge Kamalei in Hawaii Five-0
- Sydney Lassick: Benileha
- Louise Latham: Mrs. Klein
- Ed Lauter: Jonas Halloran
- Peter Lawford: Kenneth Kirk
- George Lazenby: John Cossett
- Dana Lee: Victor Fong
- Mr. Kimura in Hawaii Five-0
- Mark Lenard: Commander Hawkins/Dan Bok/Rogloff/Yoshio Nagata
- Geoffrey Lewis: Commander Chris Nolan
- Joanne Linville: Camille Carver/Dr. C.L. Fremont
- Rich Little: Johnny Kling
- Gary Lockwood: Kelsey
- Robert Loggia: Russ Hendrix
- Ed McKay in Hawaii Five-0
- Herbert Lom: Mondrago
- Jack Lord: Steve McGarrett
- Keye Luke: Senator Oishi
- James MacArthur: Danny 'Danno' Williams
- Governor Danny Williams in Hawaii Five-O (1997 Unsold Pilot)
- Gavin MacLeod: Big Chicken
- Mako: Kazuo Tahashi
- Monte Markham: Jack Ellington/Barry Dean/Jerry Rhodes/Harry Kellem
- John Marley: Noah Kaluna/Dr. Gregorius Lemira/Sam Kalakua
- Jean Marsh: Sister Harmony
- Ross Martin: Tony Alika
- A Martinez: Pepe Oliveras
- Richard Masur: Bink Avery
- Tim Matheson: Brett Saunders
- Kevin McCarthy (actor): Hunter R. Hickey/Victor Reese
- James McEachin: Captain John Anderson
- Michael McGuire: Thomas Horton
- John McLiam: Ralph Hastings
- Gerald McRaney: Tim Ryder
- Jayne Meadows: Jessica Humboldt
- Vera Miles: Flora Whiting
- Allan Miller: Frank Devlin
- Donna Mills: Marcia Bissell
- Juliet Mills: Lady Sybil Danby
- Donald Moffat: Dr. Forbes
- Ricardo Montalbán: Alex Pereno/Leonard Tokura
- Pat Morita: Phoebe
- Vic Morrow: Edward Heron
- Diana Muldaur: Andrea Storey/Cathy Wallis
- George Murdock: Hank Merrill
- Lois Nettleton: Chelsea Merriman
- Leslie Nielsen: Colonel Faraday/Brent
- Jeanette Nolan: Aunt Martha
- Simon Oakland: Mendoza/Shako Vidalgo/Marty Mauritany/Frank Epstein/Benny Kalua
- Dan O'Herlihy: Harry Wells
- Edward James Olmos: Benny Dancero
- Alan Oppenheimer: Bernie Fryer
- Annette O'Toole: Sue
- Janis Paige: Minnie Cahoon
- Luciana Paluzzi: Liana Libella
- Eleanor Parker: Constance Kincaid
- Dennis Patrick: Elliott Webster
- Nehemiah Persoff: Allie Francis/Victor Palua/Cordell/Leo Paoli/Peter Winkler/Harry Cardonus
- George O. Petrie: Austin Summers
- Barney Phillips: Cook
- Slim Pickens: Sam
- Donald Pleasence: Hans Vogler
- Jeff Pomerantz: Ted Frazer
- Lawrence Pressman: Calvin Cutler
- Stanley in Hawaii Five-0
- Kelly Preston: Wendy
- William Prince: Willard Coleman
- Andrew Prine: Richard Chadway/Wally Hatch
- Lee Purcell: Molly Taggart
- Linda Purl: Ruth
- Bill Quinn: Shawn
- John Randolph: Marty Sloane
- Robert Reed (actor): Richard Slade/Matthew Meighan
- Allan Rich: Lou Marvin
- Beah Richards: Mama Grant
- Peter Mark Richman: Nick Morgan
- John Ritter: Mike Welles/Ryan Moore
- Richard Roat: Ted Cowan
- Pernell Roberts: Lon Phillips
- Eugene Roche: Ed Hudson
- Richard Romanus: Johnny Noah
- Marion Ross: Anita/Nurse Edith Lavalo
- John Rubinstein: Joey Kalima/Harold
- Kurt Russell: Peter Valchek
- John P. Ryan: Guido Mariani
- Alfred Ryder: Harry Quon
- Albert Salmi: Vince Ryan
- Reni Santoni: Jimmy Rego
- John Saxon: Harry Clive
- Diana Scarwid: Carole
- William Schallert: Craig Wilkie/Defense Counsel Herbert
- Kathryn Leigh Scott: Jemilla
- Vito Scotti: Bill Baskin
- William Shatner: Sam Tolliver
- Martin Sheen: Arthur Dixon/Eddie Calhao
- Paul Shenar: Todd Daniels/Chadwick
- James B. Sikking: Oscar Ross/George Cameron
- Henry Silva: Elpidio Acuna
- Jean Simmons: Terri O'Brien
- Tom Skerritt: Officer Lew Morgan
- Patricia Smith: Joyce Weber
- Paul L. Smith: Andy Kamoku
- Sandra Smith: Bella Morgan/Valerie Michaels
- William Smith: James 'Kimo' Carew
- Mike Starr: Max
- Barry Sullivan: Morgan Hilliard
- Loretta Swit: Betty Landers/Wanda Russell/Anna
- George Takei: Nathaniel Blake
- Uncle Choi in Hawaii Five-0
- Malachi Throne: Reeves/Barry Bonamo
- Tim Thomerson: Mik Chandler
- Audrey Totter: Mrs. Royce
- Constance Towers: Mrs. Thorncrest
- Irene Tsu: Alia Kelly
- Manu Tupou: Eddie Chu/Cappy Pahoa/Nahashi/Abraham Meleha/Tasi
- Glynn Turman: Harley Dartson
- Joan Van Ark: Freda Cowan
- Joyce Van Patten: Rhoda Lovejoy/Lila Daniels
- Robert Vaughn: Sebastian Rolande
- John Vernon: Cal Anderson
- Christopher Walken: Walt Kramer
- Jessica Walter: Carla Crystal
- David Wayne: Monsieur Bordeaux
- Fritz Weaver: Dr. Danworth
- Larry Wilcox: Mike
- Shannon Wilcox: Andrea King
- Cindy Williams: Sue Reynolds
- Paul Williams: Stringer
- Rita Wilson: Mary Ellen
- William Windom: Senator Harlan Henderson/Ozzie Connors
- Marie Windsor: Gloria Marshall
- Jo Anne Worley: Anna Jovanko
- George Wyner: Allen Sherick
- Keenan Wynn: Hummel
- Richard Yniguez: Juan Renaldo/Carlos Rojas/Koa Vidalgo
- Anthony Zerbe: Cord McKenzie
- Bill Zuckert: Gainham/Judge
Appeared in Hawaii Five-O (unsold 1997 pilot)]:
- Gary Busey: Jimmy Xavier Berk
- Steven Flynn
- Russell Wong: Nick Wong
- Kong Liang in Hawaii Five-0
Appeared in Hawaii Five-0 (2010–2020):
- Sam Anderson: Owen Sutherland
- Carmen Argenziano: Albert Bagosa
- Reiko Aylesworth: Malia Waincroft
- Rochelle Aytes: Greer
- Daniel Baldwin: Paul Delano
- William Baldwin: Frank Delano
- Kimee Balmilero: Dr. Noelani Cunha/Allison
- Adam Beach: Special Warfare Operator Graham Wilson, 2nd Class
- Julie Benz: Inspector Abby Dunn
- Carlos Bernard: Chris Channing
- Tom Berenger: Eddie Williams
- Shelley Berman: Morty Sapperstein
- Corbin Bernsen: Henry Upton
- Michelle Borth: Catherine Rollins
- Dylan Bruno: Lee Campbell
- Jimmy Buffett: Frank Bama
- Carol Burnett: Deb McGarrett
- James Caan: Tony Archer
- Scott Caan: Danny 'Danno' Williams
- Eddie Cahill: Carson Rodes
- Sarah Carter: Lynn Downey
- Greg Collins: Victor Wyatt
- Sean Combs: Reggie Cole
- Randy Couture: Jason Duclair
- Tony Curran: John O'Toole
- Daniel Dae Kim: Chin Ho Kelly
- Mark Dacascos: Wo Fat
- Ian Anthony Dale: Adam Noshimuri
- Tim Daly: Ray Harper
- Keith David: Jimmy Cannon
- Claire Forlani: Alicia Brown
- Peter Fonda: Jesse Billings
- William Forsythe: Harry Brown
- Max Gail: Bill Walker
- Robert Gant: Thomas Stratham
- Jorge Garcia: Jerry Ortega
- Willie Garson: Gerard Hirsch
- Lauren German: Lori Weston
- Greg Germann: Robert Rovin
- Rick Gomez: Hugo Castillo
- Elliott Gould: Leo Hirsch
- Michael Graziadei: Mark Shepperd
- Melanie Griffith: Clara Williams
- Greg Grunberg: Jeff Morrison
- Daryl Hannah: Cherie Tranton
- Wings Hauser: Walter Russell
- Daniel Henney: Michael Noshimuri
- Richard Herd: Old Milton
- Jay Hernandez: Thomas Magnum
- Hal Holbrook: Leonard Patterson
- Kelly Hu: Laura Hills
- Michelle Hurd: Renee Grover
- Michael Imperioli: Odell Martin
- Gregory Itzin: Alex Mackey
- Nick Jonas: Ian Wright
- Richard T. Jones: Governor Sam Denning
- David Keith: Commander Wade Gutches
- John Kim: Endo
- Robert Knepper: Bernie Fryer
- Beulah Koale: Junior Reigns
- Bernie Kopell: Ithzak Rosen
- Michelle Krusiec: Michelle Shioma
- Christine Lahti: Doris McGarrett
- Katrina Law: Quinn Liu
- Andrew Lawrence: Eric Russo
- Joey Lawrence: Aaron Wright
- Will Yun Lee: Sang Min Soo
- LL Cool J: Sam Hanna
- Yuri Lowenthal: Liam
- Karl Makinen: Jack Anderson
- Larry Manetti: Nicky 'The Kid' DeMarco
- Taryn Manning: Mary Ann McGarrett
- James Marsters: Victor Hesse
- Chi McBride: Captain Lou Grover
- Michael McGrady: Coast Guard Captain McIlvane
- Lee Meriwether: Helen Tilton
- Dennis Miller: Bobby Raines
- Rob Morrow: Wes Cullen
- Chuck Norris: Sgt. Major Phillips
- Michael Nouri: Oscar Hirsch
- Chris O'Donnell: G. Callan
- Masi Oka: Max Bergman
- Larisa Oleynik: Jenna Kaye
- Alex O'Loughlin: Steve McGarrett
- Terry O'Quinn: Colonel Joe White
- Grace Park: Kona Kalakaua
- Missy Peregrym: Bridget
- Lou Diamond Phillips: Wes Lincoln
- Bronson Pinchot: Bastille
- Tara Platt: Allie
- Larry Poindexter: Lee Benner
- Maeve Quinlan: Sandra Fryer
- Meaghan Rath: Alexa Alani/Tani Rey
- Perrey Reeves: Anne Davis
- James Remar: Elliott Connor
- Eric Roberts: Richard Sheridan
- Elisabeth Röhm: Dr. Madison Gray
- William Sadler: Jack McGarrett
- Christopher Sean: Gabriel Waincroft
- Amanda Setton: Dr. Mindy Shaw
- Brent Sexton: Kyle Kane
- Lili Simmons: Melissa Armstrong
- Tom Sizemore: Captain Vincent Fryer
- Jean Smart: Governor Paula Jamison
- Kevin Sorbo: Carlton Bass
- Patrick St. Esprit: Vice Admiral Graham Rhodes
- Martin Starr: Adam 'Toast' Charles
- Aisha Tyler: Savannah Walker
- Claire van der Boom: Rachel Hollander
- Chris Vance: Harry Langford
- Peter Weller: Curt Stoner
- Jaleel White: Nolan Fremont
- Mykelti Williamson: Clay Maxwell
- Brian Yang: Charles Fong
- Aaron Yoo: Hideki Tashiro
