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"This might tickle."
Kamen Rider Decade's catchphrase for when he activates a Final Form Ride (see the page for more details)

"D-D-D-Double opened up! I can see inside Double!"
Narumi Akiko, in response to Kamen Rider Double achieving Xtreme Form

"I've done it, Kevin! I've successfully gene-spliced this chipmunk with a piece of provolone cheese!"
Dr. Alphonse Mephesto, South Park

"Why are his eyes mouths?!"

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"It was fascinating to watch those tentacles grow out of your eyes."

It started with stomach spasms that felt like writhing lamprey nests hatching in his belly. Then, Joe could hear the hag-fish singing in the crushing depths, even when he pretended he could not, even when the Q-tips snapped in half in his bloody ears. Madness bubbled in his brain like the bends. Then pale flesh. Then barnacle sores and wriggling growths and sea cucumber discharges. Now Joe feels the itch and burn as different species of coral battle for primacy of his chest, spitting up their digestive enzymes in time-lapse warfare. Something scuttles out of one body cavity, to be eaten by something hiding in another.
And though the seagulls hear a thousand stories, all Joe can hear is "Draug-draug-draug-draug-draug!"
The Buzzing, The Secret World

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"It was bad. She took Glory Girl with her, you know. When Gallant died, Vista saw the body. When Aegis was mashed to a literal pulp by Leviathan, to the point that he couldn’t function anymore, when he died, despite his power? I got to see the remains to verify for myself. But Victoria Dallon was still alive and they didn’t let us see. A select few adults and family members got to see her, they carted her off to a parahuman asylum and none of the rest of us got to say goodbye, because the end result was that fucked up."

"...And you look like the victim of a surgical crime,
A little Darth Vader, a little Optimus Prime
You used to be "OK"
and I liked you that way,
But I don't think that I like you "better"
No, I don't think that I like you "better"
Jonathan Coulton, "Better"

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"Enterprise. What we got back didn't live long. Fortunately."
A transporter officer, Star Trek: The Motion Picture

"Oh wow! That's a great offer. How 'bout instead I shuffle the functions of every hole in your face?"
Bill Cipher, Gravity Falls (just before doing this in response to Preston Northwest's request to join Bill's gang.)

"Gentlemen, Behold! I have grafted a deer antler onto my groin!"

"My entire body feels hot and itchy and I'm sweating all the time now. I scratched the swelling on my arm and a piece of rotten flesh just dropped off. What the hell's happening to me?"
— A portion of The Keeper's diary, Resident Evil Remake. This is tame compared to other transformations.

Diseased. Filthy, diseased, crawling things. Plagued with the infection of flesh. Disgusting. Dirty. Diseased. Weeping sores. Slice them away. Slice their bodies away before they are lost in the meat. No. Don't touch the meat. Let them boil in their prisons. Don't touch them, the filthy, crawling creatures. Keep away from them. They share their infection. They think they have carved out their cancer, but it grows. It grows in them. It waits until Gehenna to eat their flesh. To consume the corrupted, stinking meat.
CAN'T THEY SEE?"
— A Malkavian perspective on the Tzimisce, Vampire: The Masquerade - Clanbook: Malkavian (Revised)

"Real newborns aren't clean-looking gurgling bundles of cuteness. Real newborns are covered in mucus, blood, amniotic fluid, and other bodily substances, up to and including fecal matter. There is a chance they could be covered in a peach fuzz-like substance called lanugo (a remnant of when our ancestors were a lot hairier than we are now; most fetuses lose it before birth, but obviously, a few don't). They may also be covered in a waxy substance called vernix caseosum, which is basically just congealed skin oils, dead cells, and lanugo. Their skin will usually have a red hue to it as well and look somewhat "wrinkly", especially if they are considerably premature. On top of all this, most newborns have noticeably misshapen heads from the birth process, since their skulls aren't yet closed and their bones are very flexible. To say nothing of the placenta that should be popping out with the babe. Even newborns that have been cleaned up and are a couple days old are generally Ugly Cute at best. It's been said that all newborn babies look like Winston Churchill."
This Very Wiki, from Three-Month-Old Newborn, explaining exactly why most people are revolted at the sight of newborns and babies.

God hadn't looked out for Roy Benson, didn't matter how much he prayed or kept his hands to himself. His fingers were swollen and blackened, and his face was covered in dark tumors, red at the edges and black at the center. One masked the entire left half of his face, closing the eye to a slit and disfiguring his lips so that they turned up at one side in the semblance of a grin. Jerry could make out what was left of his teeth, barely held in place by his rotting gums, and his distorted tongue flicking in the cavern of his mouth. Black fluid flowed like oil from his nostrils and his ears and the corners of his mouth, pooling on his chin before dripping onto the floor. He said something, but Jerry couldn't understand what it was. All he knew was that Roy Benson was rotting away before him, and crying because he couldn't understand why this was happening to him.

This poor unfortunate had a tire blow at something way over the speed limit on an open but empty field. By the time anybody else came along, gremlins had scuttled away with his unconscious body and begun repairing it. They dug out the fragments of his splintered ribs, kept his heart beating with bits of an old alarm clock and gave him a solid metal chassis underneath his chest. He didn't do much more than moan and squirm a little, though, so they began to look for other problems. Ultimately, they replaced his entire trunk with plastic and rubber, and replaced his clumsy digestive system with a processing plant for simple diesel. The characters might discover the Gremlin Victim dying by the side of the road, desperate for fuel, or they might be sent to rescue him when he doesn't arrive somewhere as planned. Of course, he's not long for the world after the gremlins finish with him...

Itchy skin, inflamed and peeling. Mouldering scabs, decaying, dribbling. That was how it started. Then bouquets of angry boils swelled tender and ripe. And bilious slime, dimly amber, curdled in jaundiced wounds. Rivers of putrid phlegm cascaded from scarlet sores as fractured bone ruptured rotting flesh. Crimson agony soaked into tattered clothing. Sullied body and soiled garment twisted and merged... a swirling mosaic of fused fresh and fabric. That was how it continued. Sidney Crumb is ill.
Captain Britain, "Sid's Story"

And then there were the people who went six months in its presence. The first team, you see, it never occurred to them that they were breathing in spores. I should show you photos. I think I have them on a memory stick in the bag somewhere. When they cut old Massey open, they found three mycoprotein heads growing in his stomachs, like doll's heads carved out of toadstools.
Reddin, Supergod

If you need to go to the bathroom after this next series of tests, please let a test associate know, because in all likelihood whatever comes out of you is going to be coal. Only temporary, so do not worry. If it persists for a week, though, start worrying and come see us, because that's not supposed to happen.
Cave Johnson, Portal 2

If you've cut yourself at all in the course of these tests, you might have noticed that your blood is pure gasoline. That's normal. We've been shooting you with an invisible laser that's supposed to turn blood into gasoline, so all that means is it's working.
Cave Johnson, Portal 2

We're working on a little teleportation experiment. Now this doesn't work with all skin types, so try to remember which skin is yours, and if it doesn't teleport along with you, we'll do what we can to sew you right back into it.
Cave Johnson, Portal 2

The shimmering legions come for us, and we must dance to the beat of their drums. The spell-men of the Great Changer throw their will into the sky, and the air crackles with light and colour. We are lost! Why can't you see? He will melt my shape like he did his soldiers. He will give me fingers instead of legs and teeth instead of eyes. He'll steal my soul and make me giggle his rhymes, and I'll be counted as one of his, because Sigmar won't want me then. No one will want me then.

Some say that when the Nuclear Promethean's disfigurements show, he has no skin. Or maybe what skin he has is red and sloughing off from eternal sunburn. Some say that he breathes radioactive fire. One account tells of bleeding eyeballs; another tells of bleeding pores, the whole surface of the body so slick with hemorrhaged blood that it could be used to contaminate objects and spread radiation sickness like a plague. Other tales tell of him leaving behind irradiated clumps of skin. Descriptions of huge tumors abound, enormous lesions and growths that spread, turning into fleshy armor or sometimes extra limbs, which sometimes grow faces and limbs of their own before detatching and walking away.

The Qlippothic Sphere of Life is growth gone horribly wrong. It embodies cancerous growth and parasitism. The fecundity it encourages is vibrantly sick, pregnant with half-formed monstrosities and self-strangling over-abundance. Qlippothic Life magics are the magics of plague and parasite, and they feed on true Life magics the way a tick draws blood from its host.
Mage: The Ascension - The Book Of Madness

But Nikolai, who lay there breathing with terrible difficulty, had had a strong, healthy body too. "And now that bent, hollow chest... with that awful rippling below his skin... and I not knowing what will become of me or wherefore..."
"It is... it is inside..." his brother's voice called elusively.
"What... what do you mean, inside?" Levin replied. "What is inside?"
Nikolai thrashed in the sheets; he was not awake, but talking from the depths of some consuming nightmare.
"It is inside me... deep inside... get it out... please... please, brother..."
Android Karenina

Jackson lurched forward, as if about to be sick, and coughed up a long, ragged snake. It dangled from his mouth like a particularly vile old school tie. The Vice-Chancellor's head hung uselessly, but the snake - new organ, whatever? - darted about, alert. There was an eye where its head should have been, blinking sideways.
Things began to push at Jackson's suit from the inside. Damp patches appeared. Gabrielle's head fell from his lap and rolled across the floor.
What had been Jackson stood up. His old flesh hung like a tramp's suit on the living skeleton of new growth. Feeble hands were pushing his clothes apart.
The cobra-necked eye looked at Brian, then at Monica. He could not read any expression in the thing.

...And the asshole said to him, "It's you who will shut up in the end. Not me. Because we don't need you around here anymore. I can talk and eat and shit.
After that, he began waking up in the morning with a transparent jelly like a tadpole's tail all over his mouth. This jelly was what the scientists call un-D.T., Undifferentiated Tissue, which can grow into any kind of flesh on the human body. He would tear it off his mouth and the pieces would stick to his hands like burning gasoline jelly and grow there, grow anywhere on him a glob of it fell. So finally his mouth sealed over and the whole head would have amputated spontaneous - (did you know there is a condition occurs in parts of Africa and only among Negroes where the little toe amputates spontaneously?) - except for the eyes, you dig. That's one thing the asshole couldn't do was see. It needed the eyes. But nerve connections were blocked and infiltrated and atrophied so the brain couldn't give orders any more. It was trapped in the skull, sealed off. For a while, you could see the silent, helpless suffering of the brain behind the eyes, then finally the brain must have died because the eyes went out, and there was no more feeling in them than a crab's eye on the end of a stalk.

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