Plutarkian Lawrence Lactavius Limburger from the original 1993 Biker Mice from Mars series disguises himself as one of these in order to fulfill his people's mission as Planet Looters.
The revival had Ronaldo Rump, a No Celebrities Were Harmed parody of famed industrialist and eventual President Donald Trump, who teamed up with the Big Bad Catatonians to further his business empire. He has a cousin named Sir Richard Brand Something.
Malory Archer is the head of private sector global espionage firm ISIS (International Secret Intelligence Service). In addition to being a Bad Boss to her employees, including murdering the cleaning staff when they tried to unionize, she is supremely selfish to the extent where she does things that threaten (inter)national security if they are lucrative enough. Or if they merely please her, such as her decades-long affair with the head of the KGB. Her main rival Len Trexler, head of ODIN (Organization of Democratic Intelligence Networks) is very similar and infatuated with her.
Buzz Lightyear of Star Command had a minor recurring villain named Norbert Klerm, who runs a company called Comp U Klerm and at one point attempts to market a series of robots designed to annihilate Star Command.
Looten Plunder, from Captain Planet and the Planeteers, was of this type. He was also the only villain on the show whose motive for pillaging the Earth was all that plausible, most of the others having fantastic motives (Duke Nukem physically thrived on radiation) or doing it out of sheer malice.
Hoggish Greedly was of the slovenly Corrupt Hick type. He didn't seem to show outright malice for the environment, he usually just didn't care about it, and his motives were centered on obtaining vast amounts of money and resources as fast as possible.
Sly Sludge was a corrupt exec who focused on waste disposal (that is, dumping absurd amounts of toxic waste and garbage wherever) and was sleazy and sneaky. He often ran operations that would shrink garbage or compact it or incinerate it, but they either were fake or they backfired severely.
About 50% of Dr. Blight's evil schemes revolved around making herself famous, rich or preferably both, including more than once when she teams up with one of the above characters for some malignant corporate venture. She usually supplies the hyper-advanced tech they need to do their thing. The other 50%, on the other hand, were messing up the environment for the heck of it.
Mr. Boss is a Child Hater who at one point schemed to have his employees' children shot into space just so they'd have much longer workdays. To make this ironic, three Sector V operatives (Numbuhs Four, Three, and Two) have parents who work for his company, while Numbuh 86 is his daughter.
"Operation: R.A.I.N.B.O.W.S." introduces Mr. Mogul, who owns the company that makes Rainbow Monkey toys. After noticing that Numbuh Three is able to pick up the scent of Rainbow Monkeys without error, he manipulates her into helping him find real Rainbow Monkeys so he can do something sinister to them. What he intends to do with the real Rainbow Monkeys isn't revealed, but it's strongly implied that he intends to kill them and make their bodies into toys. He also had no problems with doing the same thing to Numbuh Three once she found out his plan.
The main villain Father owns a corporation called Evil Adult Industries, Inc. The name of the company alone should be an obvious indication that he uses it to do nefarious things.
Derek Powers from the first season of Batman Beyond typifies this trope. His son, Paxton, who later succeeds him, is pretty corrupt too, but is not nearly as competent as a villain, nor as involved in the day-to-day running of the company.
Mercy Graves takes over LexCorp when Luthor is outed as a criminal in Justice League, and manages to bring it back into solvency by being not quite as corrupt as Luthor (or possibly just less maniacal).
Roland Daggett from Batman: The Animated Series is a deconstruction of this trope: in each of his four appearances in the series, Dagget gradually loses his fortune as legal fees and criminal charges catch up to him. He finally faces jail time after his fourth appearance and is not seen again afterwards.
Ferris Boyle (also from Batman) is one of these as well; being responsible for turning Victor Fries into Mr. Freeze and supposedly killing his wife, Nora. Bonus for being voiced by Mark Hamill, before he became The Joker.
Grant Walker (again from Batman), who blackmails Mr. Freeze into trying to make him immortal.
Maxie Zeus (Batman again) is also depicted as a corporate executive who... well... went a little nuts after his stock crashed. The reason he became insane was that his success in crime made him think he was untouchable and godlike.
Edwin Alva, Sr., the head of Alva Industries from Static Shock plays with this. While he's quite crotchety and has a grudge against Static, he rarely targets the young hero. His only redeeming quality is remorse for how he treated his son.
Darkwing Duck's foe the Liquidator was once Bud Fludd, the owner of a bottled water company who was poisoning his competitor's water supply. An accident turned him into a water controlling supervillain, but his old traits stick around; for example, he once flooded the city so he could sell "Liquidator Brand life rafts" at a ridiculously inflated price.
The episode "Chubby Cheese" revealed that the head of the titular restaurant chain was actually using Chubby Cheese's as a front for amassing lots of money and taking over the world.
The TV movie Ego Trip showed that in the future, Mandark would take over the company he and Dexter worked for and eventually use its resources to take over the world and rule all of humanity.
On Dilbert when the title character and Wally become part owners of their company they meet the other CEOs. Reading back the minutes of the last meeting one informs them that "we gave each other stock options, discussed ways to ignore the needs of others and Hamilton had a racial joke."
Bob Santino from Dogstar. He was willing to destroy every dog on Earth so he could make a profit selling his robotic dogs.
HP, the Head Pixie from The Fairly OddParents! He's voiced by Ben Stein (as are the other pixies) and has got to be the most boring creature in Fairyworld.
Carter Pewdterschmidt on Family Guy. Originally, he was just an idiotic Manchild who doesn't understand the world outside of business. Post-cancellation, he's just outright evil.
The Filmation's Ghostbusters episode "The Battle for Ghost Command" features a man who illegally dumps toxic waste at the city's sewers, unknowingly attracting ghosts until the Ghostbusters discovered the truth.
Armando Gutierrez from Freakazoid! knew about the flaw that gave Dexter powers but refused to recall his product because it would affect sales. He is both voiced by and obviously physically modeled after Ricardo Montalban. His ambitions later grow beyond profit margins when he decides to exploit the flaw so he can become a powerful Freakazoid too.
Mr. Twitchell from the Frosty the Snowman sequel Frosty Returns. He plans to use his product Summer Wheeze to eliminate snow forever and doesn't care about how his actions would affect the environment. He even punishes one of his subordinates for questioning his ethics by dumping her through a trap door.
"That Guy", an '80s executive whose name we never learn (the script for the episode referred to him as "Steve Castle"), was a comic exaggeration of this trope.
Parodied with Leo Wong, who is a compendium of every criticism ever levelled at corporations.
The Crimson Twins Tomax and Xamot are depicted this way in G.I. Joe: A Real American Hero since they are affiliated with the terrorist organization Cobra and they use their company Extensive Enterprises to give Cobra funding.
"Batteries Not Included", the first episode of the Garbage Pail Kids Cartoon, had the Garbage Pail Kids fight the Funbusters, who attempted to destroy every toy in America by creating and distributing batteries that would ruin any toy that used them.
Demona and Thailog become these when they create Nightstone Unlimited, under the assumed identities of Dominique Destine (who is never seen at night) and Alexander Thailog (who is never seen in person).
The Gravedale High episode "Save Our School" had a hotel owner who calls herself The Empress, who wants to put a chain of her hotel where the school is and even hires a health inspector in order to condemn it so she can have it torn down.
Stavros Garkos, the main villain of the animated series Hurricanes, is the head of Garkos Enterprises and is usually seeking for dishonest ways to increase his wealth and/or turn his soccer team into world champions.
The series also introduced a villain named Douglas Fir, whose character is similar to Garkos.
Also in that series, when Napper Thompson's uncle died and left his fortune to him on the condition Napper never plays soccer again, Napper became the target of two villains who wanted to get the inheritance. One of the villains was the uncle's former business partner. Napper lost the inheritance but fortunately, it was revealed neither villain was the appointed next heir.
Eric Raymond from Jem starts the series owning half of Jerrica's music company and does everything he can to sabotage Jem and the Holograms or stop them from beating the Misfits, even if his methods put people's lives at risk.
Master Blaster in Kidd Video is an evil disc producer, coherent with the music-themed nature of the show. He wants to make the eponymous band his slaves.
Interestingly, in Kim Possible, Drakken's two plans that came closest to succeeding involved becoming this, first over Bueno Nacho, and the second over Hank's Gourmet Cupcakes (everyone associated Dr. D with shampoo for some reason).
Hiroshi Sato framed a competitor with association to the Equalists.
Season two has Varrick, who while an ally of the protagonists supposedly deals with the triads, instigates a war with the Northern Water Tribe because their blockade is ruining his business, is not above bribing his way out of a situation and engages in war profiteering. He's also revealed to be escalating the war for profit as well as secretly bankrupting Asami's corporation so that he can buy it out from her. Despite this, he's not evil so much as amoral and he's usually willing to help Team Avatar if it suits his needs (or just because he likes them).
Fisher Biskit from Littlest Pet Shop (2012)initially isn't cartoonishly corrupt, but he is the owner of a large Predatory Business that initially threatens to put the titular shop out of business and in the episode "Heart of Parkness" apparently has no problems harboring an endangered species of snake, or in "Littlest Bigfoot" making a pet shampoo that requires an entire tree to produce one drop. Hisdaughters were much worse, at least prior to his characterization in "A Night at the Pawza", where he tries to prevent a pet hotel from opening long enough for him to open his own.
Somewhat subverted, as there is actually a greater evil out there, The Tribunal. Ofdensen's just preventing them from killing Dethklok.
James Grishnack, producer of Dethklok's movie "Blood Ocean" in Season 1, has a fitting line for this trope: "I've been fucking over celebrities since you were all shitting in diapers!"
Season 3 has Damien. He was the son of the executive that first signed Dethklok. He disliked death metal and had a grudge against Nathan Explosion for punching him. Upon taking power from his ailing father, he cut off Dethklok's finances and shut down a concert in order to force Dethklok into signing a new contract, one that would give him the lion's share of profit. Only the timely interventionof the thought-dead Ofdensen stopped him, and he got punched by Nathan again for trying to attack Ofdensen.
Some shorts feature Bluto and Popeye as business rivals. For example, one had the two of them competing for a military contract to build warships.
In the Al Brodax short "Spinach Shortage", Bluto Expy Brutus monopolized spinach and was withholding it to raise prices. While it's anyone's guess if he did anything illegal to obtain his spinach monopoly, it's still illegal to abuse monopoly even if it was obtained fair and square.
Cyril Sneer from The Raccoons, but the trope is gradually subverted as the series progresses as he eventually grows a conscience and his principled son, Cedric, eventually takes over the business as a partner.
Milton Midas on the other hand, is a much more straight example, as his actions of disposing toxic waste cause a lake to become contaminated.
Rich Buckner from the Thanksgiving episode of Regular Show. When his ultra-patriotic Thanksgiving song loses out to Mordecai and Rigby's song in a contest to obtain an actual turducken (born every million years), he steals the turducken anyway because it contains a golden wishbone that grants actual wishes, which he intends to use to obtain the rights to Thanksgiving. Mordecai and Rigby stop him in the episode's definitive Moment of Awesome.
Angelica takes the role of one in one Rugrats episode. The hallway to her office has portraits of many Corrupt Corporate Executives (which includes a Wicked Witch and a devil). Her office looks like it's located in Hell, her pigtails are devil horns, and she chases Tommy and Chuckie with insanely creepy robot businessmen.
Tommy: Boss Angelica...
Tommy: You don't have to be so mean to us...
Angelica: Oh, I don't, eh? Well, let me tell YOU something! If I wanna be mean, I CAN be mean! Know why? ...CAUSE I'M THE BOSS! I CAN DO ANYTHING I WANT! AND IF YOU DON'T LIKE IT, I CAN HAVE YOU FIRED!
Mr. Burns. He's dumped radioactive waste at public parks and playgrounds, sold weapons to the Nazis, stolen a trillion dollars in foreign aid money from the U.S. government, and (most famously) built a giant sun-blocking device to keep Springfield shrouded in perpetual darkness, all so his electric company could have a truly complete monopoly over the town's energy supply.
The big-guy-versus-little-guy version is subverted in the "Gnomes" episode. Tweek's dad's coffee shop is threatened by the imminent arrival of a Starbucks-esque chain, and he conscripts the kids into encouraging the town to prevent this. However, the kids learn from the Underpants Gnomes that successful corporations often get that way because they have a better product. When the townsfolk actually try the chain's coffee, even Tweek's dad agrees it's far superior to what he was making, and the town relents.
A particularly foul-mouthed and violent version of Mickey Mouse is used as a representation of Disney's shadier corporate actions, such as their exploitative use of teen idols as well as their control over franchises.
Several Native Americans owning a large casino who threatened to tear down South Park to make way for a highway also count.
CEO of Walmart is a subversion. He seems corrupt at first but is in fact a slave to Walmart itself.
"Chef-Aid:" "I am above the law!"
"The Entity": The airline industry
Season 22 has Jeff Bezos, depicted as a tyrannical telepathic alien enslaving Amazon's workers.
In Season 23 and the "Tegridy Farms" arc, Randy Marsh, having become wealthy from his Tegridy Farms marijuana industry, becomes this, blowing up homegrown marijuana gardens to maintain his monopoly, making a deal with the Chinese to kill Winnie the Pooh, parading his wealth all throughout South Park gained from his aforementioned Chinese deals (despite full knowledge that China is only buying weed to plant to protesters), killing a dozen cows after his Tegridy Burger bankrupted the meat industry, and selling a mutated version of his Halloween Special to everyone. As a result, everyone finally gets fed up with Tegridy Farms and gets arrested.
Dan Halen from Squidbillies is not just a corrupt executive but an embodiment of pure evil whose company was founded to spread misery and death, going so far as to release a product called the Baby Death Trap.
That was mostly so he could sue people referring to one of his other products as a "baby death trap", presumably under the guise of trademark protection (since the original product was probably too dangerous for a libel suit to hold up in court).
Oroku Saki/The Shredder from Teenage Mutant Ninja Turtles (2003) series is one of these. His supposed "office building" in New York is also the main headquarters of the Foot Clan. His adopted daughter, Karai, later inherits his position as CEO of his public corporation as well as head of the Foot Clan during his banishment at the end of one season.
Montana Max from Tiny Toon Adventures is a teenage version of this. He owns a number of environmentally-unfriendly factories that make frivolous things such as elevator buttons and donut holes, which Plucky Duck often tries to stop as his superhero alter-ego, the Toxic Revenger.
The Transformers: Failed mayoral candidate Shawn Berger, the owner of a multi-billion dollar company, is tricked into teaming up with Megatron in order to convince the people of Earth that the Autobots are evil, and the Decepticons are the good guys, in the 2 part episode "Megatron's Master Plan".
Porter C. Powell from Transformers Animated. Just ask Sari Sumdac, who found herself kicked out of her own home as part of Powell's extremely hostile takeover of Sumdac Systems. He immediately rehires the clearly insane Henry Masterson, who had previously threatened to cause a nuclear meltdown on national TV, so he can break into the military market that Professor Sumdac kept the company out of. He then allows Masterson to steal Sentinel Prime's body and bails him out when he gets caught, on the basis that alien robots don't have rights. Don't worry, it all comes back to bite him.
Powell: There's no room for sentiment in business.
Mr. Big from WordGirl, who is an evil executive who had a tendency to brainwash people.
Yogi's Gang: Mr. Hothead of Hothead Enterprises. He has a device that turns people into hotheads and uses it on Yogi's Gang as part of a plan to force Cindy to sell her dude ranch. He later sabotages the ranch's water supply.