Webcomics as a medium are fairly new. The first known webcomic began in 1985 ("Witches and Stitches"), but the medium didn't really take off until 1993, making it one of the oldest types of New Media, but still incredibly young compared to something like Literature or even Film. Running for over a year is still a pretty good chunk of webcomic history; running for 10 years means you've been around for a large portion of it.
Naturally, webcomics this old are a prime source of Archive Panic, so beware.
Since webcomics are prone to long hiatuses, please use common sense when adding an example: if the webcomic has not actually been running for at least 10 years, then please don't add it no matter what the start date is. Webcomics are sorted within folders, first by start year, then alphabetically. Discontinued/finished comics have a different set of folders organized first by how long they ran, then alphabetically.
Ongoing:
- Help Desk
- Sabrina Online - note
- College Catastrophe in 2000-2013note , continued as Nine to Nine since 2014
- Diesel Sweeties
- Megatokyo
- GUComics
- Sinfest
- Little Gamers
- Sacred Pie
- Ctrl+Alt+Del
- El Goonish Shive
- Girl Genius
- Irregular Webcomic!. 2002-presentnote
- Legostar Galactica
- Phil Likes Tacos
- Sam & Fuzzy
- Saturday Morning Breakfast Cereal
- Unshelved. 2002-presentnote
- The Whiteboard
- Carry On
- Charby the Vampirate
- Grim Tales from Down Below
- The KAMics
- Kaspall
- Las Lindas: Detailing Mora Linda's ongoing efforts to run a dairy farm.
- Magellan
- Maliki
- Powerpuff Girls Doujinshi
- Requiem
- Rhapsodies
- Slightly Damned
- Two Lumps
- Caribbean Blue: Cats and Cat Girls in adventures in the tropics.
- Cyanide and Happiness
- Daily Grind
- Flaky Pastry
- Gunnerkrigg Court
- Exiern
- Goblins
- Kuro Shouri
- Life On The Fourth Floor
- Planescape Survival Guide
- Sequential Art
- xkcd
- Awkward Zombie
- Bittersweet Candy Bowl (currently have so 138 chapters and six volumes so far)
- Carciphona
- Doc Rat
- The Eyeof Ramalach: Adventurers searching for a buried treasure, they find an Eldritch Abomination.
- The Inexplicable Adventures of Bob! (originally in print, 1993-1997)
- Lackadaisy
- New Adventures Of Queen Victoria
- The Non-Adventures of Wonderella
- Survivor: Fan Characters note
- Yet Another Fantasy Gamer Comic
- Weregeek
- At Arm's Length
- Cerintha
- Dragon Ball Multiverse
- EarthBound: The Chosen Four: A Web Comic adaption of the titular game.
- Housepets! (Main storyline concluded May 9th, 2023, future uncertain.)
- Knighthood: Detailing Joy's adventures to becoming a knight.
- Naru-Hina Chronicles
- Nerf NOW!!
- Sandra and Woo (currently on indefinite hiatus; most recent strip
is uploaded on November 26, 2022, although Novil, the author of this webcomic, recently said he's planning to return making more strips of it sometime in 2023)
- Square Root of Minus Garfield (Of interest: Has been updating daily since 2010, with more than 3500 strips as of January 1st, 2019)
- Addictive Science: The adventures of mad scientists.
- Bug Martini
- Hero Oh Hero: started as A Path to Greater Good, stopped in 2011, restarted in 2013.
- Kiwi Blitz: A teenage girl with a kiwi-shaped Mini-Mecha fights evil and makes poor choices. Mainly the latter.
- Mountain Time
- Rascals: A slice-of-life involving a group of 20-year-old anthros and the Usagi family.
- Terra
- Thistil Mistil Kistil
- Uh-Oh, It’s a Dinosaur
- Dumbing of Age
- Maximumble
- Paranatural
- Selkie: A webcomic about adoption, family, friendship, betrayal, and forgiveness... with a supernatural twist.
- Spinnerette: A lab accident leaves a girl with spider-man-like powers, including 4 extra arms.
- A Tale of Fiction
- Tower of God
- Unsounded
Concluded or discontinued:
- Nukees. 1997-2022
- Schlock Mercenary. 2000-2020
- Castlevania RPG. 2002-2022
- Walkyverse. 1997-2015note
- Zebra Girl. 2000-2018
- Newshounds. 1997-2014
- Gene Catlow. 2001-2017 (creator's death)
- Melonpool. 1996-2012. Rebooted in October 2014; the original strips are now only available in print collections.
- Namir Deiter. 1999-2015
- Achewood. 2001-2016
- Misfile. 2004-2019. Succeeded by Misfile Universe: Hell High.
- Skin Horse. 2007-2022
- Zortic. Zortic classic: Mar 2000-Jul 2008 + Zortic: Oct 2008-Jan 2016
- Breakpoint City. 2000-2014
- Chopping Block. 2000-2014
- Argon Zark. 1995-2008
- Crimson Flag. 2008-2021
- Doctor Fun. 1993-2006
- Exterminatus Now. 2003-2016
- Goats. 1997-2010
- Unlike Minerva and You Say It First. 1999-2003 and 2004-2013
- User Friendly. 1997-2010
- The Adventures of Dr. McNinja. 2005-2017
- Archipelago. 2005-2017
- A Softer World. 2003-2015
- Darkbolt. 1999-2011
- Dominic Deegan: Oracle for Hire. 2002-2013
- Rain. 2010-2022
- Bruno. 1996-2007
- Girls with Slingshots. 2004-2015
- Chirault. 2007-2018
- 8-Bit Theater. 2001-2010
- Errant Story. 2002-2012
- Octopus Pie. 2007-2017
- Ozy and Millie. 1998-2008
- Surviving The World. 2008-2018 note
- Theater Hopper. 2002-2012
- Think Before You Think 2009-2019 *
- What The Duck. 2006-2016 note
- Yamara. 1996-2006 (started in print 1988)
- Sugar Bits. 2007-2016