The Canterbury Tales have a Butt Monkey character with this name, but that's probably more in reference to him being "pretty" (as was the Biblical character) than because of ill-omens associated with the name.
Cry The Beloved Country features Absalom Kumalo, son of an African preacher who ultimately ends up killing a man (to be fair, it was something of an accident).
The first, and by far the most powerful angel in Neon Genesis Evangelion. The mere act of waking up this being wiped out half the population of earth and changed most of the major landmass. Oh, and when Adam woke up it's four wings were large enough to be visible from space.
The notorious seducer who betrayed Samson. While Samson's name suggests a violent killer, Delilah's tends to suggest a temptress and an evil woman
Spider-Man villain the Rose (Jacob Conover) employed a cybernetic female enforcer named Delilah, both as a bodyguard and an assassin. (Unlike her namesake, she seemed to have Undying Loyalty towards him.)
One of the two villains from The Proposition is named Eden Fletcher. His first name kind of gets him on here. Since he's an evil decadent type, and, better yet, a SmugSnake his name makes perfect symbolic sense.
Any medical experiment named "Project Lazarus", run by a Dr. Lazarus, or building "the Lazarus Device" will be intended to cheat death or even return the dead to life. Bringing back the dead and cheating death is Meddling In God's Domain, and almost certainly go horribly wrong and punish all involved.
Doctor Who: The Tenth Doctor's incident with a Dr. Lazarus. The episode title was "The Lazarus Experiment."
Sanctuary had the Lazarus virus and while it only infected abnormals not human, the infected nonetheless became hazardous to human health as a result of the disease. Among abnormals it was also lethal.
Shepard is revived by the "Lazarus Project" in Mass Effect 2 with no ill effects. However, the Project is simply the reason s/he survives being killed and remains the player character, rather than a significant plot point.
Archbishop Lazarus of Tristram from Diablo. If Big D isn't running the show, he is. Then again, Big D is always running the show. Still, the guy's a bastard.
An ancient conqueror mentioned only once in Genesis. Given that the first half sounds like a Portmaneau of "numb" and "dim," and what "rod" can mean, this name's level of badass may have decayed a bit by now. (Bugs Bunny calling Elmer Fudd "Nimrod"note Elmer Fudd, of course, being an utterly incompetent hunter, the exact opposite of Nimrod's reputation among the Bible's authors. certainly didn't help.)
Similarly, there's a serial killer named Nimrod ("a mighty hunter before the Lord" and all) in The Doll's House from Sandman. Which also has the Corinthian, named for the Biblical symbolism of "through a glass, darkly" (as a dark mirror of humanity) as well as for the themodeofbehavior, with his particular twist on it.
A subversion in the Doctor Who episode "Ghost Light". Nimrod is the name of the originalBig Bad's Neanderthal butler, and a worshipper of the actual Big Bad, a Physical God known only as Light, but he's a good guy.
The Whoniverse has another Nimrod - an Ax Crazyundead government agent hell-bent on world domination by Britain, and complete control of Britain by his organization, the Forge, which should be itself put around here given its Orwellian type of evil and willingness to abuse alien tech.
In the two-part episode, "White Light" of Mighty Morphin' Power Rangers Season 2, Lord Zedd creates a monster literally named Nimrod the Scarlet Sentinel.
An excellent zig-zag of the trope is Samson from Carnivŕle, who is the dwarf manager of the carnival. He isn't particularly evil or physically imposing, but he was once a weightlifter and is certainly closer to the supernatural elements of the show than other characters.
Poppy Z. Brite's Lost Souls's character. Interestingly, Brite's Zillah is male.
The third book in Madeleine L'Engle's Time Quartet, A Swiftly Tilting Planet, revolves around women of a particular line all named "Zillah/Zylle/Zyll". Zillah is actually the middle name of Meg's mother in law, who sets the events of the story into motion and is central to the conflict.
Captain Ahab, named after an evil king from the Old Testament.
Ahab's wife Jezebel qualifies as well. In the first Kingdom Keepers book, Finn runs across a girl named Jez, who flat out admits it's short for Jezebel, from The Bible. Not being a biblical scholar, Finn fails to realize he should be worried.
Carnivŕle, fittingly enough for a show about Biblical catastrophes and superpowered beings, has many Biblical names, but not among the villains. The only Biblical connection on the dark side is Tommy Dolan, his first name being an excellent and prophetic reference to "doubting Thomas".
The fourth season of Heroes featured as its Big Bad one Samuel Sullivan, a Dark Messiah who promised to lead the "specials" to a promised land where they would be free of persecution. In the Bible, Samuel is the prophet who essentially founded the Kingdom of Israel.
LOST has a lot of Biblical names. Ironically, the show's resident Magnificent Bastard is named Benjamin. This should refer to Jacob, too, now that Ben has started to turn into the real powers' Butt Monkey.