open/close all folders
Dracula as the Original Vampire
- The original Dracula is this, of course. It's known he's the original vampire of his line of vampire, but not if he is the first vampire ever.
- Dracula in Blade: Trinity is said to be the ancestor of all vampires. Of course, he's also the strongest. Blade's Dracula (AKA Drake) is not only the strongest but is also immune to any vampire weakness and can make himself look like anyone.
- Ditto for Dracula in Van Helsing.
- Ditto again for Alucard from Hellsing, who is said to be the first vampire.
- Jared Nomak, the progenitor of the Reaper strain in Blade II, is also immune to all but sunlight. His heart is protected by a hard shell, except for under the armpits. Unlike his progeny, who are all ravenous monsters who die if they don't feed for 36 hours, he is smart and calculating.
- In Dracula 2000, he's not only the first, but he's also Judas Iscariot.
- Dracula isn't the first vampire in the Marvel Universe, but he is the first vampire's chosen successor and the current leader of vampire-kind. His predecessor Varnae committed Suicide by Sunlight after growing weary of his unending mockery of life.
- Dracula is explicitly the first vampire in existence in Department 19, and the nearer to his transformation that one of his victims was bitten, the stronger they are in the present day.
- Inverted in Buffy the Vampire Slayer season 10. Dracula is not the original vampire, but he is most universally-recognised one. However, Xander writes in the Slayer Handbook (a book that makes anything written into it reality) that Dracula is "the most powerful of all vampires". This results in Dracula transforming into the Old One Maloker, the real progenitor of vampires.
Anime and Manga
- In Berserk, The Idea of Evil is the progenitor of all demons—including the five members of the Godhand whose job it is to create new Apostles.
- In Claymore the Yoma were created by the very organization that supposedly fights them from experiments on two Asarakam held captive by the Organization. What's REALLY disturbing is that one of them is a juvenile and the other is an adult, and by mixing their genetic material together, you get the parasitic worms that mutate humans into Yoma. Ew.
- Lucy from Elfen Lied is the only fertile Diclonius, and spreads the mutation to the gametes of any human she touches with her vectors.
- Fullmetal Alchemist has the homunculus Father. The name speaks for itself. He was created as a homunculus some time before the start of the series, but he is responsible for the creation of the other homunculi.
- In Mahou Sensei Negima!, it is implied that Evangeline may be one of these. She's been around for centuries, has none of the classic weaknesses of vampires, was not bitten by another vampire, but transformed in an experiment by the Lifemaker, is capable of transforming people into her type of vampire, and has been identified as being of a specific race of vampire.
- Neon Genesis Evangelion has Adam, the first Angel. Lilith, the second Angel, is the progenitor of the human race, which is collectively the 18th Angel Lilin.
- In Seraph of the End, the entire vampire race is descended from a group of obscenely powerful "Progenitors". By the time the series began, the First Progenitor (aka the first and the most powerful vampire) is said to have disappeared several centuries ago after siring Second to Fifth Progenitors, who in turn sired Sixth to Twentieth Progenitors. The Twentieth (weakest) Progenitors are still One-Man Army, whose physical abilities can't be matched by any human fighters, even those armed with the most powerful demon weapons. Therefore, they have to resort to teamwork and tactics in order to defeat lower-ranking Progenitors. Fighting higher-ranking ones is practically suicidal in most cases.
- In the manga version of Soul Eater, we eventually find out that Excalibur is the first demon weapon, upon which all others were based. It's still not clear where he came from in the first place, though.
- Kuran Kaname from Vampire Knight may not be the original progenitor of the race, but he was one of the original purebloods, exerted a huge influence during his lifetime, and founded the royal line of purebloods who kept track of the species. Plus, he's totally badass in his current incarnation.
- Hellblazer had the King of the Vampires, who was the first vampire and the one from whom all others descend.
- In the Wolverine Story Arc "Old Man Logan," Bruce Banner is the progenitor of the Hulk Gang.
- And in the mainstream verse, all Gamma mutates like the Hulk were descended from one common ancestor who was the first person born with the specific genetic quirk that grants people superpowers when exposed to gamma radiation instead of death by radiation sickness.
- The Marvel Universe has quite a few of these: Varnae is the first vampire, created by dark magic; various demons like Chthon and Set are the progenitors of monstrous races like the N'Garai and the Serpent Men; and the demonic villainess Lilith, who resembles her folkloric namesake in having a legion of supernaturally-powerful children called the Lillin.
- A Love Like Blood:
- Lord Karkossa is the vampire from whom all others derive, who was apparently a Roman soldier who drank the blood of Christ. His direct offspring are also stronger than other vampires, such as his son possessing wings and being able to summon swarms of bats.
- Lord Romulus is presumably the same for the werewolves, though we don't get any look into his backstory other than his name alluding to the two mythical brothers who were weaned by a wolf bitch before founding the city of Rome.
- Black Moon Chronicles: The dragon species was spawned by a single primordial dragon, who is of course the biggest. He doesn't show until the end of the world approaches when he wakes up from his centuries-long slumber to lead his children through the spacegate.
- In the Pony POV Series, there are several examples:
- Havoc and Entropy are the parents of the Draconequi, though it's noted they aren't actually Draconequi themselves, they merely made them in their image.
- Azerhorse is the single parent of the Outer Concepts.
- Lilith the Witch Queen is the ancient ancestor of Hydia's clan of Witches, and as would be suggested by her other epitaph "The First Witch", is the first witch to ever exist after discovering the Pandora's Box Morning Star sent to Equus as part of his rebellion. She is immensely powerful, to the point she is no longer even human and now composed of pure evil magic. She is so evil and powerful, even her own family is terrified of her, and considered releasing her from her prison a Godzilla Threshold. If she hadn't been defeated, she'd have likely destroyed all life on the planet. Even now her evil and unholy power remains, sealed inside and corrupting the Alicorn Amulet.
- Lahb, one of Lilith's creations, is the first and most dangerous of the Polyphemus Gargantula, more commonly known as Giant Cyclops Spider. Being forty feet tall, Lahb was powerful enough to curbstomp a small army of centaurs singlehandedly, only meeting her end when Tirek hijacked the power of Pandora's Box.
- Queen Tiamat and King Bahamut are both the most powerful of all dragons, as well as their Mother and Father deities, and thus this trope for the Dragons.
- In both Queen of All Oni and Queen Of Shadows (co-created by the same authors as part of Project Dark Jade), the Shadowkhan originated when Kagehime, the daughter of Izanami and the lord of the Underworld, escaped to the surface world. Seeing her shadow for the first time (as there's no light in the Underworld) and mistaking it for a man, she politely asked it to get her some fruit from a tree that she couldn't reach; touched at her actions, the shadow transformed into the first Shadowkhan, Hiruzen, and all of the species later followed after from the two of them.
- In The Librarian: The Curse of the Judas Chalice, Judas was the first vampire, but Dracula is not him. In fact, Dracula was crippled for centuries after drinking plagued blood.
- In Underworld, William Corvinus is the Progenitor of all Lycans. Markus Corvinus, his brother, is the progenitor of all Vampires. Unlike other Lycans, William cannot change back to a human. Markus, was unremarkable until he was accidentally turned into a hybrid.
- Alexander Corvinus is the progenitor of all immortals, but he chooses to live like a normal human and displays no power outside of immortality, which gets him chewed out by Selene.
- Drinking his blood does give Selene enhanced strength, endurance, and resistance to sunlight.
- Unlike other Lycans, William is an albino and has the most wolfish appearance. He can also spread the Lycan virus with his claws. This strain of the virus is so potent it can even turn the dead. These first-generation werewolves are mindless beasts with a wolfish appearance. Second-generation werewolves (the ones properly called Lycans) are the ones that are more civilized and can engage in Voluntary Shapeshifting.
- Alexander Corvinus is the progenitor of all immortals, but he chooses to live like a normal human and displays no power outside of immortality, which gets him chewed out by Selene.
- At the end of Gojira, one of the main heroes suspects that Godzilla may be just the first of his kind. Cue the sequel, Godzilla Raids Again, and it's revealed that he's right as another Godzilla shows up.
- Howling II: Stirba: Werewolf Bitch features the queen and original werewolf Stirba.
- In The Faculty Marybeth is the alien queen. Killing the queen kills all of her alien offspring, freeing the hosts. This doesn't free the host of any injuries he might have received while infected, to one victim's dismay.
- In Slither the alien that takes over Grant Grant acts as this, creating himself a "brood queen" which spawns the parasites that give the movie its title. These infect people, turning them into ravenous zombies. Some of them seek to merge with Grant, while others produce more parasites. Killing Grant ends the infection.
- In Dagon it is revealed that all the fish-monsters in Imboca are either children or followers of Dagon.
- It's implied in The Lair of the White Worm that the eponymous worm spawned a race of snake-like vampires. It's also possible that the film's antagonist was one of the first or possibly the first.
- In John Carpenter's Vampires, Valek is the first vampire, accidentally created during a botched exorcism. He is the strongest, as the only thing that can hurt him is sunlight. He lacks every other vampire weakness. His goal in the movie is to complete the exorcism in order to become truly immortal. This would also allow him to make other vampires without weaknesses.
- In Dracula 2000, the eponymous vampire turns out to be Judas Iscariot and progenitor to all vampires. He is nearly impossible to kill (the only way is to recreate the conditions of his origin) and is able to turn any other vampire back into a human (although the ending implies that this might be only temporary).
- The xenomorphs of the Alien series have a queen as the center of their hive. Though normally stationary, she is the biggest, strongest, and smartest member of her species.
- In Hellbound: Hellraiser II, it is revealed that the original creator of the cenobites is a giant, diamond-shaped deity named Leviathan, Lord of the Labyrinth and God of Hunger and Desire, torturing and tormenting human souls into cenobites to serve him for eternity.
- In Nightbreed, the nightbreed worship a monster god called Baphomet who supposedly created them, having revealed at the end of the movie to be real.
- X-Men: Apocalypse: En Sabah Nur is the world's first mutant and the most powerful one. Over the millennia, he accumulates the abilities of all of his mutant hosts, so he's virtually god-like.
- Glen Cook's The Black Company series:
- The Dominator is the original creator of the northern empire, and the one who Took all of the Ten Who Were Taken.
- Old Father Tree is the cause of the uncounted number of strange creatures on the Plain of Fear, or at least the change storms that caused them. HE also refers to the menhirs as his people.
- In Anne Rice's The Vampire Chronicles, Akasha is the first Vampire, and the progenitor of all of them. She became a vampire when a demon entered her body and fused with her flesh.
- She is the strongest, especially after draining her husband and second vampire Enkil. She can fly, hypnotize hundreds of humans at a time, incinerate almost any vampire she sees, and track any of her progeny, which she uses to kill off the majority of the world's vampires.
- Additionally, any damage she sustains is mirrored by all other vampires to varying degrees. For example, when a vampire set her living statue out into the sun, many older vampires had their flesh seared, while the younger ones simply burst into flames. When Akasha is finally killed by decapitation, every vampire falls on the floor, feeling as if their heads were being removed. By eating Akasha's heart and brain, Mekare (the fourth vampire) becomes the host of the spirit Amel and the new queen.
- Another vampiric example: In Human by S.M. Carrière the Nosphoros are this to the Opyri in general.
- The Biblical murderer Cain is a Monster Progenitor by implication in the epic poem Beowulf, as both Grendel and his mother are said to be his descendants. Grendel's mother is a more direct example in the same work.
- Ungoliant, progenitor of the giant spiders in The Hobbit and The Lord of the Rings's Shelob, from The Silmarillion. This also applies with Draugluin, the first of werewolves, and Glaurung, the first of dragons.
- The Mother of All Darkness from the Anita Blake series is the ancient progenitor of vampires and possibly werecreatures. Given the series has featured pre-Cro-Magnon vampires, that makes her pretty old.
- Yaksha in The Last Vampire was once a stillborn infant in 3000 BC, but Demonic Possession revived him as the first vampire.
- In The Dresden Files, the Red King is the Red Court Vampire from whom all other Red Court Vampires are descended. This turns out to be a major weakness in Changes when a bloodline curse that was intended by the Red King to kill all members of Harry's family resulted in the death of every single Red Court Vampire when it was turned back upon the Red Court.
- According to Paradise Lost, while many of the demons are actual examples of Fallen Angels, others are the spawn of Lucifer/Satan and his daughter Sin, making them Monster Progenitors.
- In Hogfather The Bogeyman was the original personification of primitive man's terror at the darkness and what hid within it. After they mastered fire other bogeymen were born, lurking in the shadows cast by fire but never knowing the primordial darkness that spawned their ancestor.
- In the web-novel Domina, Lilith, the First Monster, is an honorary example. She was the first person to use the Bio-Augmentation device known as the toy maker, so everyone else who uses it sees her as the "Mother Monster." Lilith herself is annoyed at being called that, but still fills the role as best she can.
Maria: It is a city of orphans. I suppose it's only natural they'd latch onto a mother-figure.
- The Fablehaven series has Ephira the tree spirit as the first creature corrupted by the demon Kurisock.
- Tedrin in Eden Green infects the main character and her best friend with an alien needle symbiote; Eden views him as Patient Zero and hopes that destroying him will save the world from his parasite.
- Shaitan is the first vampire in the Necroscope series and the inspiration for the figure of Satan. Shaitan was the first human (in his home dimension) to be infected with the lovecraftian parasite that causes vampirism.
- Father Dagon and Mother Hydra as the parents of the Deep One race in the Cthulhu Mythos. In any case several of the Old Ones that appear in the mythos had different offspring both as monsters races and as other forms of Eldritch Abomination.
- Season 6 involves the Winchesters tracking down Monster Progenitors, known as "Alphas". Alphas do not typically have the weaknesses of their children, and may share some telepathic connection to them. The respective Alphas are in turn topped by their progenitor Eve, the Mother of All Monsters. It was in turn implied in Season 7 that Eve is herself descended from the Leviathans, which were the first beasts created by God, even before angels.
- Lilith was the first demon, being a human soul that Lucifer personally twisted as an act of defiance against God.
- The premise of Werewolf was a man hunting down the werewolf who bit him to kill him and end his curse.
- Mr. Snow from Being Human is said to be ultimately the progenitor of every other vampire in the show. He may even be one of the first vampires ever, but this is unlikely since the first vampires are said to have been a pair of Ancient Chinese brothers who made a Deal with the Devil, and Mr. Snow is Caucasian-looking and ginger.
- The six Originals from The Vampire Diaries. They were the first vampires ever created by a witch, and all vampires in existence come from one of their bloodlines. Like all other vampires, they cannot enter the home of a human without an invitation, and vervain is still toxic to them and can block their compulsion. They have the same weaknesses as other vampires, but to a lesser degree: sunlight will burn but not kill them, and a wooden stake to the heart will only kill them temporarily. They are far more powerful than even the oldest non-Originals, have the ability to compel other vampires, and are practically impossible to kill. Unlike other vampires, they can be forced into a state of death-like hibernation with a special dagger dipped in the ash from a particular tree, and can only truly be killed by a stake carved from that same white oak tree. Additionally, when an Original is killed, all vampires descended from that Original's bloodline spontaneously die off within a few hours.
- Doctor Who:
- Davros, creator of the Daleks, isn't a Dalek himself, but with his Dalek-esque life support machine and Omnicidal Maniac tendencies, he's halfway there.
- We also have General Sontar (of whom the Sontarans are all clones), Jamie (Patient Zero of the "Empty Child" gas-mask zombie plague), and The Master (founder of the "Master Race"). The last surviving Racnoss tried to become this and recreate her species, but the Doctor killed all her babies.
- Inverted with John Lumic, who created the alternate-universe Cybermen but only later became a Cyber-controller (against his will).
- The Wirrn in "The Ark In Space" have a very complicated life cycle and figuring out how it works from the limited evidence is crucial to the Doctor's plan to stop them.The monster progenitor is a Queen who travels through space to find a suitable host. Once she finds one, she lays her eggs inside it, and the larva eventually hatches, consumes the host and goes on the move. Through consuming the host, the larva gains its knowledge and some elements of its personality, and it then goes on the move to find further hosts to transform into Wirrn by covering them in slime, causing the resultant creature to have the knowledge of the original host as well as of the further host. As the life cycle continues a "swarm leader" with a huge amount of knowledge is created and is capable of controlling other Wirrn.
- On Buffy the Vampire Slayer, most of the first vampires were sired by the Old One Maloker as soldiers to fight humans who rose up against the Old Ones. One of the most powerful vampire bloodlines (The Master > Darla > Angelus > Drusilla > Spike), though, was founded many eons later by another Old One named Archaeus, long after the other Old Ones had been banished from Earth.
- True Blood has Lilith, the first vampire. However, she is long dead by the time the series takes place. A vial of her blood is stored in the headquarters of the Vampire Authority. There is a growing movement among vampires that opposes "mainstreaming" and integrating into the human society instead of trying to rule the humans and slaughter them like cattle. Bill ends up drinking Lilith's blood and becomes "Billith".
Mythology And Religion
- Lilith, Adam's first wife in Jewish mysticism, bred with demons and spirits of the earth and air and thus birthed the lilim, a race of half-demon, half-humans.
- As opposed to Dracula, Vampire: The Masquerade pegs Cain(e) as the First Vampire, cursed by God for his slaying of Abel. His line was then split down into three childer (destroyed before the Flood), and thirteen childer unto them, whose ranks and divisions make up the thirteen clans of vampires who exist in the modern nights. The rules for fighting Cain, in their entirety, are "You lose."
- Each Promethean Lineage (think Frankenstein's Monster) has at least one Progenitor, created by a human demiurge. Each Progenitor can create more of their kind by using human corpses in a ritual specific to the Lineage.
- In Werewolf: The Forsaken the werewolves claim descent from Father Wolf and Mother Luna. However, there came a time when his children thought Father Wolf was getting too old to adequately guard the border between the mortal and spirit world, so they killed him.
- Beast: The Primordial: Beasts believe themselves to be the children of an entity known as the Dark Mother, among other things. And they claim the progenitors of all the other "monster races" in the New World of Darkness as siblings.
- In the Ravenloft boxed set Castles Forlorn, it's suggested that Tristan apBlanc may be this trope for the race of living monstrous humanoids called "vampyres", by way of his half-human daughter. Elsewhere in the Core, Doctor Heinfroth is the progenitor of the cerebral vampire strain of undead.
- In Tristessa's Gazetteer V writeup, she's Ravenloft's first widderribhinn (undead fey), a type of undead created when a fey dies through powerful magic or brutal violence. All widderribhinn who arise in the demiplane are compelled to travel to her domain and submit to her as their ruler.
- Dungeons & Dragons 3.5 has the demon known as Pale Night. Her title is "The Mother of Demons", and while it is uncertain she actually fits the Trope, it is stated in several other sources that she is a mother to something, although they disagree on what. Many demon lords claim they are her sons, with another source claiming "she is the mother of several tanaríri lords, including Grazízt, Lupercio, and Vucarik of Chains." The Black Scrolls of Ahm claim she is the mother of nothing less than the tanaríri race (the tanar'ri are by far the most common types of demons). Yet another source says she is not a mother of demons, but the mother of several monstrous races on the material plane. Pale Night will not confirm or deny any of this (and few are insane enough to try asking her, given what happens to most who are caught trespassing on her property.)
- Also from Dungeons and Dragons, there is the deity Io, The Ninefold Dragon. He's the progenitor of all Dragonkind (and in some myths: the creator of the entire D&D multiverse), and the father of Bahamut and Tiamat.
- In Magic: The Gathering, Baron Sengir is the progenitor of the Sengir Vampires.
- Genestealer Broodlords/Patriarchs in the Warhammer 40,000 universe. Granted, an individual broodlord/patriarch is usually pretty "young", often "only" a hundred years old, but the cult he spawns certainly revere him as this trope.
- Much like Dracula is the progenitor of all vampires in various fiction, the various Vampire clans in Vampire Counts are named after their progenitor (or their nickname, such as the case of Abhorash the Blood Dragon). The clans of vampires were in turn created by Nagash, the First Necromancer and the "creator" of both undead factions and recently became the patron god of the undead.
- In this setting and in 40k, it's implied that the Chaos Gods can create their Daemons as aspects of themselves, tearing a bit of essence from their body which subsequently gains sentience. The Chaos Gods are also implied to simply be the biggest, oldest and most powerful Daemon of their kind, but the gap between them and their strongest lieutenant is so wide that no one, daemon or mortal, can ever challenge them for their titles (one tried to challenge Khorne, and was subsequently tossed so far into the sky that he flew for 9 days straight).
- The Emperor Ing in Metroid Prime 2: Echoes. Scan logs will tell you that it "is the strongest Ing in the horde, the alpha and the omega," and that "like its brethren, the Emperor Ing is a metamorph."
- Raziel's vampiric brethren in Legacy of Kain: Soul Reaver all create fledgling vampires that share certain traits with their progenitors. Raziel and his brothers were themselves turned into vampires by Kain.
- In the Nasuverse, Crimson Moon can be considered the progenitor of True Ancestors and, through them, all vampires. While he didn't exactly spawn them, Gaia used him as a template for her purported defenders against humanity, which didn't go well, since all of them inherited Crimson Moon's Blood Lust alongside an unfortunate quirk of Gaian elementals: going insane when they drink blood. It's easy to see how this went badly.
- The Dragon Age setting had the Tevinter Magisters who entered and subsequently corrupted the Golden City of The Maker. This, in turn, has corrupted them into the first Darkspawn, who then spread this corruption as a Mystical Plague to start the First Blight. At least one of these Magisters, Corypheus, is still alive and more or less sane a thousand years later, as evidenced by the Dragon Age II DLC. He becomes the Big Bad in Dragon Age: Inquisition.
- In Dragon Ball Online, Majin Buu begets an entire race of Majin creatures, which is one of the playable races in the games.
- In Mass Effect 3, krogan legend states that Kalros is this to the Thresher Maw species. This is probably just myth, but Kalros is by far the largest and most dangerous Thresher Maw in existence and proves perfectly capable of taking down a Destroyer-class Reaper single-handed. It's mentioned that Thresher Maws reproduced by spore, thus anyone encounter can possibly become its carrier and spread it across the galaxy.
Garrus: When the krogan name a Thresher Maw, you know you're in trouble. They don't think anyone is ever going to kill it.
- The Leviathan DLC explains that Harbinger is this to the Reapers.
- Most of the enemies that appear in The Subspace Emissary mode of Super Smash Bros. Brawl are made of Shadow Bugs extracted from Mr. Game & Watch's body.
- The Elder Scrolls lore tells of a woman named Lamae Beolfag, chronicled in the book Opusculus Lamae Bal. Created through a traumatic rape by Molag Bal, the Daedric Prince of Domination and Enslavement, Lamae became the first recorded vampire, dubbed "Blood Mother." It is believed that all Vampires descend from her, upsetting the balance of death and rebirth normally administered by the Aedric God Arkay.
- Confirmed in the Skyrim: Dawnguard DLC. We are also shown the Volkihar Clan of eastern Skyrim, who are unlike their Cyrodilic cousins are Vampire Lords and owe their unique and more powerful form due to being gifted with vampirism directly from Molag Bal himself. They likewise share several traits of Molag Bal, such as voluntary shapeshifting, being capable of telekinesis and permanently charming victims.
- Subverted in Guild Wars 2 in that the Pale Tree is the Progenitor of the entire Sylvari Race (or at least all the Sylvari that appear in the game except one), however, the Sylvari are the exact opposite of a monster race. In fact, they are one of the playable races of the game.
- Played straight, however, with the Elder Dragons, who are the progenitors of various types of monsters, including but not limited to Dragonbrand, Destroyers, the Risen (Undead), and various other monstrosities.
- Alex Mercer of [PROTOTYPE]. Created by accident when the dead body of a human was infected with the most powerful mutagenic virus ever designed, he began the game as a Humanoid Abomination, was well on his way to Eldritch levels by the end, and was creating more of his kind by the second. Even the title of the game refers to the rarely-used definition of the word "prototype," meaning the first of a new species.
- The ancient Demonking Demise/The Person of the End/The Tyrannical Being from The Legend of Zelda: Skyward Sword is the origin of all demons in the Zelda Series.
- This seems to be a common feature among demons, since Batreaux from the same game also seems to summon monsters with his presence. During nighttime in Skyloft, Keese, Chuchus appear and the Remlits turn feral. Once Batreaux becomes a human, the monsters stop appearing and the Remlits remain tame at night.
- Of Orcs And Men has Styx, an Orc deformed by abuse of magic, as the progenitor to the goblin race—hence why he's the only intelligent goblin around. The prequel Styx: Master of Shadows shows that goblins are essentially just inferior clones created by Styx that he spawns for various purposes and the Styx that's the protagonist of the games is actually a clone himself that the real Styx infused enough magic for him to retain his intelligence.
- Wander in Shadow of the Colossus is the progenitor of the horned boys and, by extension, shadow children in ICO.
- Age of Mythology has Fenris Wolf Brood and Jormund Elver, making the mythological Fenris Wolf and Jormungandr (the Midgard Serpent) their Monster Progenitors.
- Five Nights at Freddy's 2 reveals that the Puppet is the one responsible for causing the animatronics from the first game to act as homicidal as they are by haunting them with the souls of five murdered children. One minigame implies that it was the first animatronic to go wrong by being haunted with the soul of the aforementioned child murderer's first victim.
- Sol Badguy of Guilty Gear was once a brilliant scientist who tampered with biological augmentation and magic to create a new race of transhumans, the titular Gears. However, he was betrayed and turned into one himself by his evil former friend, and boy does he regret it all. He won't rest until all the other Gears and his former friend are lying dead.
- Guilty Gear actually subverts this trope in a few ways. Despite Sol being the Super Prototype, he's only a prototype in the sense that he's the first Gear to exist. It is Justice, Type-01 and the first "complete" Gear (though Xrd -SIGN- calls into question if she's the first Gear produced after Sol), who shares a genetic link to all other Gears and thus able to control them as a Commander Gear (though Sol is immune to her powers due to predating Justice; presumably, the handful of other Commander Gears are similarly unaffected by Justice's psychic commands). However, Justice is not directly responsible for the creation of other Gears with the exception of her daughter Dizzy (who is hinted to also be the daughter of Mr. Badguy himself). Justice's bloodline, consisting of Dizzy and Dizzy's son Sin, proves to be important in Overture because they carry a genetic key signature that is necessary for the plans of that game's Big Bad.
- In Stubbs the Zombie you play as Patient Zero of a zombie outbreak. While most of the zombies Stubbs creates are the normal shambling kind he's marginally more intelligent and gradually obtains a rather disgusting array of special abilities.
- Futurama features the original Were-car, Project Satan, who is the origin of the curse of all Were-cars.
- Codename: Kids Next Door had an episode where Numbah 5's teacher, Miss Thomson, was the Queen were-dog responsible for turning her student into were-dogs, including Numbah 5's rival, who, as a were-poodle, ate her homework in a previous episode. Unlike the other were-dogs the queen were-dog was able to eat Numbah 4's awful homework without becoming sick. However, as soon as her cursed necklace was taken off, she and all the rest returned to normal humans.
- In one episode of Thundarr the Barbarian the heroes ran into a conflict between an evil wizard and a pack of werewolves. The leader of the werewolves had turned innocent humans into his pack and he wanted to add the wizard to his ranks. The day is saved when the heroes discover a magical pool of water that can undo lycanthropy. All of the werewolf leader's victims are restored to normal after being bathed in the pool. When the werewolf leader is bathed in it, he turns into...a wolf. Ariel realizes that he was the original werewolf. He was never human in the first place.