Biological, but unnaturally created humans, ranging from "biological robot" to "clone".
Anime sometimes uses the term "android" for them, in a way different than the West. Ironically, this is closer to the original meaning, which according to the dictionary, is "An automaton that is created from biological materials and resembles a human" (Often in these cases, the term "Bioroid" may be used to classify them separately from the contemporary definition of Android).
The important thing is that Artificial Humans look like humans, they move like them, etc. Some may be bullet proof, but you wouldn't be able to tell from touch. Sometimes the only physical indicator is eye-color, which may be red, yellow or purple, or an unusual skin/hair pigment. Not always, though, and given the range of eye and hair color in anime, it's not a perfect indicator.
Artificial Humans often have cognitive traits typical of a robot, such as mathematical skill and a perfect memory on the positive side, and uncreativity and excessive literal-mindedness on the negative side. Many of them also have the same kind of loyalty to their creators that robots tend to be programmed for — although A.I. Is a Crapshoot in the case of the Artificial Human just as it is when it comes to the electronic version of artificial intelligence.
But many of them have more in common with humans emotionally than robots. They are often outsiders, so their emotional states are often in the "angst" category, which leads to bonding with the kind-hearted hero(ine) or Kill All Humans!. If in a society that fully accepts them, there is usually no emotional difference.
Like robots outside anime, it doesn't matter what they're created for, they'll usually have increased strength, speed, and other powers. See Super-Powered Robot Meter Maids.
Note that the very first use of the word "robot" in fiction, the eponymous "robots" from Karel Capek's R.U.R. (for Rossum's Universal Robots), were actually Artificial Humans and not the clanking metal humanoids we now associate with that term. Actual clanking metal humanoids do go back to the Greek myth of Talos and Hephaestus' automatons in the 5th century BCE, but that's another trope.
Just like most artificial humanoid characters, Artificial Humans tend to Become a Real Boy over the course of the plot. Mechanical Evolution is often invoked in their origins.
See also Creating Life, Robot, and Spaceship Girl. Compare Ridiculously Human Robot. Contrast Forgot He Was A Robot.
Dragon Ball Z has Cell, who couldn't be called a human by any means, was a manufactured organism engineered by Dr. Gero by taking genes from each of the Z fighters.
A straighter example would be the 8-20 series of Artificial Humans Gero created/developed before Cell. However, #17, #18 and #20 (who was Gero himself) were cyborgs.
That's right, #17 and #18 were normal human twins until Gero messed with them. That's why #18 and Krillin could have a kid so easily. It's not obvious in the English dub because the Japanese word meaning "artificial human", used for both Gero's robots and Gero's cyborgs, was translated as "Android", giving the false impression that #17 and #18 were robots like #16 and #19. Vegeta even has a line in the dub where he says that #18 moves fast "for someone who's made of metal".
Note that #20 (Gero) isn't a cyborg in the same sense of #17 and #18. #20 is actually a entirely robotic construct, the same type as #19, except with Gero's brain in a jar... in #20's head.
Bakuretsu Tenshi: Jo and Marion were designed by the rival syndicate to be the "ultimate battle angels".
Key The Metal Idol claimed to be an android, although her exact nature isn't revealed until much later.
Ryoko from Tenchi Muyo! was grown from a test-tube by Washuu.
As is OVA Kagato being he was the hermaphrodite clone of Naja Akara, Washuu's best friend, that took over a Ryoko prototype and split off his female half.
Neon Genesis Evangelion: Rei Ayanami and Kaworu Nagisa are human/Angel clones, and the Evangelions qualify at some level, as they have biological bodies similar to huge human organisms (actually copied from Adam, but Angels/Apostles in Evangelion are basically what humans would be if they rejected their "humanity"), a human soul, and are literally called "jinzouningen", meaning "artificial humans".
Also, the Philosopher's Stone-infused dummies. Although, since they contain Philosopher's Stones, they might technically count as a type of homunculus anyway.
Noah from Soul Eater. He was the 3rd Big Bad until it was found out that it was the Book of Eibon's Table of Contents that created Noah
Fate Testarossa, the Wolkenritter, Erio Mondial, the members of the Numbers (including Subaru and Ginga), Vivio, Jail Scaglietti and all familiars from Magical Girl Lyrical Nanoha. Notable in that they're all three kinds; clones, living programs, and cyborgs.
Yuki in Haruhi Suzumiya fits here, though what exactly she is is obscured by her Technobabble explanation. As do Ryouko Asakura and Kimidori Emiri.
Perhaps we can use the Hyperion novel referenced in the series as a guide and deduce that Yuki is a cybrid, an artificial intelligence with a humanoid body.
In the 9th novel, yet another Artificial Human — one in direct opposition to Yuki — is introduced in the form of Kuyou Suou.
Annapuma and Unipuma from Dominion Tank Police are called androids. However, Uni is the original, and Anna was actually cloned from her, suggesting a biological origin.
Despite their name, Bioroids in Appleseed are actually genetically modified human clones. They are identical to humans except for reduced capabilities to feel strong emotions and the lack of their cells ability to freely perform cell division. As a result they require regular injections to regenerate cells and lack the capacity to reproduce. Which is a good idea, as they are far more numerous than regular humans in Olympus. However Hitomi and Yoshi seem to be at least in a romantic relationship, though it's unclear if it is also sexual.
Also, Athena seems perfectly capable of governing Olympus with a very strong fist and by intimidating the human politicans into compliance. Nike is really the only bioroid who shows limited emotions, but that makes her appear even much more dangerous and intimidating.
The Sexaroids of Bubblegum Crisis were a rather distinct homage to the replicants of Blade Runner, complete with a "what is human?" Aesop for Priss, who notably hated Boomers before meeting Sylvie.
Similarly, the Thirds of Armitage III seem to have been heavily inspired by replicants. They appear indistinguishable from humans and, on the emotional scale, are actually more emotional than many humans due to having been created for the purpose of motherhood.
Rozen Maiden revolves around dolls which act nearly human other than size.
More accurately she isa piece of software that had a body built around it. Or, well, that's not quite true either. It seems that she's something that has been in the Wired since its birth, and possibly existed before it in some other form. Her human body is artificial, though.
Or possibly she's just the collective soul/memory/(un)conscious of mankind. Or she could be god. Given that this is Serial Experiments Lain, it's difficult/impossible to tell.
The main character and several members of the supporting case of Yokohama Kaidashi Kikou are androids who are oddly biological in some ways (they must eat and sleep and are basically human in personality) and definitely mechanical in others (getting struck by lightning doesn't seriously hurt Alpha, just requires that her skin be re-coated). The rather leisurely plot of the series spends a lot of time focusing on the nature of these androids.
Trigun 's Vash, Knives, Tessla, Chronica, Domina, and all the other plants are genetically modified alien creatures with some astonishingly human characteristics.
The "Humaritt" Lila from Najica Blitz Tactics is created in a laboratory and possesses superhuman abilities. Her responses are often rather robotic at first, but she gets better.
The Arume in Blue Drop create synthetic children that are seemingly their exact copies - aside from the tendency to explode. Originally used to battle the earth forces, they are later applied to fend off the remnants of the Arume's rather nasty biological weaponry.
Mewtwo in Pokémon: The First Movie was never intended to be human, but the girl grown in the tube next to him was a clone of one of the scientists' deceased daughter.
Mewtwo himself in Pokémon Special, since Blaine spliced some of his own DNA with Mew's to create him.
Edel from Princess Tutu was created by Drosselmeyer to influence the path of the story. She's typically called a puppet, probably in reference to the ballets Nutcracker and Coppelia, but although she's strange none of the characters seem to realize this until The Reveal. Uzura, who was made from the wooden remains of Edel, also counts.
In Gundam 00, it is heavily hinted that the Innovators, along with Tieria Erde and Nena Trinity may be like this due to their innate ability to interact with the supercomputer VEDA.
Hinted no more in season 2 and outright confirmed in The Movie where Tieria himself confirms that Innovades are basically a Virtual Ghost uploaded into organic hardware. If the hardware in question suffers fatal damage, they simply Body Surfback into Veda and optionally create themselves a new body - or just stay uploaded and play Deus Est Machinaas Tieria did between the series finale and the movie.
Touko of Kara no Kyoukai created a number of perfect copies of herself (physically and mentally) using her skill as a dollmaker. She uses them as backup copies of herself, in the sense of "it doesn't matter if I die because my other bodies will live on and do what I would've done." She doesn't seem to care which one is the original or whether its still alive.
As usual - with Kinoko Nasu that is - the 'truth' is more complex. Touko achieved a level of sophistry in "copying" herself, that the copy is no longer distinguishable from the original hence it ceases to be a copy and Touko can no longer tell which self is really "her".
One morning, Hiroshi wakes up to find himself naked and miniaturized to the size of a mouse. When he gets Kyoko to help and she takes him back to school, he meetshimself! Turns out the class decided to experiment with homunculi using the real Hiroshi as a sample, but the tiny result ended up inheriting the original's memories and personality. In the end, Kyoko takes pity on the devastated mini-Hiroshi and creates a homunculus of her own. The two of them go off into the wilderness to make a life for themselves.
Away on an expedition, Nube is caught in a landslide and ends up trapped underground. After several days, realizing no one is coming to rescue him, and slowly going insane from lack of human contact, he breaks the ultimate taboo: he gathers human remains found in the cave, and enchants them back to life —creating a golem-like girl who likewise latches onto him. It doesn't end well, and is a surprisingly somber plot in an otherwise comedy manga.
All of the ruling Elites of Ai No Kusabi are artificially created and their hyper-evolved brains are the only organic human components they have left of their constructed bodies. They look and sound human, exhibit very little human emotion and look down on humans.
In Mahou Sensei Negima!, current Big Bad Fate Averruncus appears to be an Artificial Human. Evangeline (the "Doll Master") claimed that he moved like a construct, and Fate himself has claimed that he was "made". Not to mention that his real name is Tertium, Latin for "The Third."
Chachamaru recently took a step up from average Robot Girl after having a near-emotional-breakdown on whether on not she had a soul, or if her existence was simply a collection of data. However, it's proved shortly thereafter that she does, possibly qualifying her for this trope.
And let's not forget that the majority of the inhabitants of the Magical World are actually sentient illusions.
In the world of Eve No Jikan, all androids must have a holographic halo otherwise they'd be indistinguishable from humans the lone exception is a bodyguard; the titular coffeehouse is the only place where they can turn it off and "relax", and it's revealed can drink coffee, cry, enjoy music, fall in love, and generally behave like Ridiculously Human Robots. Oh, and they're Three Laws Compliant.
Hikaru in Figure17, who is accidentally created from a Powered Armor "Figure" after protecting Tsubasa in a battle. Hikaru becomes Tsubasa's artificial twin sister.
Primula from SHUFFLE! is an artificial life form, of the magic variety.
Juno of Element Hunters is one. The real only way to tell is her stating herself to be one though.
Akise of Mirai Nikki turns out to be one. Luckily he manages to prove his existence as an entity by doing something of his own free will. Even Deus Ex Machina acknowledges it, and he's the one that made him.
The Neogenics from the Witchblade anime, who are specifically designed to be Witchblade bearers. They age rapidly, which means Maria is basically a 5 year old girl with the body of a teenager.
Pinoko from Black Jack is a special variation: She was supposed to be born as a normal human being (the Identical Twin to an unnamed other girl, to be exact), but a bad case of the medical condition "Fetus in Fetu" occured during their mother's pregnancy, and Pinoko's organs (including her entire, working nervous system) ended up within her sister's body. After managing to plea Black Jack for help telepathically, he removed the cyst containing her from her twin's body and built an artificial body for Pinoko, effectively making her a "full" person.
The last guardians of the Pyramid in Yaiba, namely Ruby, Sapphire, Diamond and Emerald. The Platina Company is also apparently working on building the Ultimate Fighter.
Rosario + Vampire revealed Outer Moka to be a partial example. She's a "fake personality" created to care for the sealed Inner Moka, but is also noted to be possibly the most lifelike one ever created, and was probably derived from her mother's personality.
In Toward the Terra, everyone could technically be considered Artificial Humans to some degree, as society under the SD System no longer uses natural birth and all children are developed in Uterine Replicators. Within the context of the setting, however, Physis and Keith are especially noteworthy: rather than being concieved using an egg and sperm from pre-selected parents, they were engineered completely artificially by the Mother Computers and grown nearly to physical maturity in People Jars - Physis, deemed a failed prototype, was decanted fairly young and thereafter rescued by Soldier Blue, but Keith didn't come out of the jar until the age of fourteen.
Judge Dredd, both Judge Ricos and all of Dredd's clones, in Judge Dredd. In the spin-off audio dramas from Big Finish, it's mentioned that much of Justice Department is made up of clones. Also, there's Mean Machine Angel, a cyborg nutcase with an emotion dial on his forehead.
Wonder Woman was a "perfect woman" created from clay by her "mother", Hippolyta.
The Golden Age Human Torch, android hero of WWII, is visually indistinguishable from a human being.
Aside from bursting into flame when exposed to oxygen-rich air?
The Vision's body is a temporal duplicate of the android Human Torch's body, with some modifications and a different personality. Whatever those modifications were, the Vision is usually depicted as having a lot more inorganic bits than the Torch does.
Adam Warren's Livewires are a team of ridiculously human mecha who will be very cross with you if you call them robots. Seeing as they're derived from Life Model Decoys, it makes sense that they are so physically and emotionally human. Subverted in that they can and do hack their own neurology whenever human feelings and failings get in the way of doing their job.
Several appear in Give Me Liberty, and are very convincing copies of real people.
Cybersix and the rest of the Cyber series, the Techno series, and the Frankenstein's Monster-like Fixed Ideas, with the Cybers looking the most human, being virtually undetectable as not human, and the Technos a close second.
Boba Fett and the clone army of Star Wars are all artificial clones of Jango Fett.
The upcoming Crisis Crossover movie between Kamen Rider Double and Kamen Rider OOO will feature an artificial human who is apparently a cell-medal-based clone of Oda Nobunaga, who was responsible for the unification of Japan in the late 16th century.
In Transformers Decepticons utilize Facsimile which created from humans the Decepticons kidnapped, they are used to fulfill the Decepticons needs which involve them infiltrating human society. When they die they disintegrate into green goo.
In David Wingrove's Chung Kuo, the GenSyn corporation makes brutish animal-men, as well as attractive female servants.
The title character of Robert A. Heinlein's novel Friday is treated as such, even though she is human, just genetically engineered and grown in an artificial womb. Boss even chided her for thinking she was anything other than human in his first appearance.
In the Discworld book Thief of Time, the Lady LeJean is one, created directly from raw atoms by the Auditors. At one point, many many Auditors create and "pilot" one, but at the end when she decides to kill herself she is surprised to find out she has a soul that survives her death.
Rei Toei from William Gibson's cyberpunk novel Idoru is a sentient artificial intelligence whose "body" is a hologram.
Several characters in Bernard Werber's novels and short stories are androids or part of an artificial-life simulation software but don't know it. In fact, some of his works suggest that all of the characters and even all of humankind, the gods, and the whole known universe might unwittingly be part of a giant software and/or experiment. Yup, Werber is a fan of Philip K. Dick.
Frankenstein's Monster is one of the most classic and well known examples. While it is stressed at certain points through the original ''Frankenstein novel that the monster is an entirely unique species, he certainly has a human intelligence and personality.
Hyperion Cantos has biroids, biologically manufactured androids. They're bright blue to keep them out of the uncanny valley.
Terrence Cee (and his sister/wife Janine) in Lois McMaster Bujold's Ethan of Athos is one of these; he suffers some identity problems because he was genetically engineered from a careful selection of genes by a secret military project. But as Ethan points out, we're all a mishmash of our ancestors' genes, and everyone in his society is born from replicators (and donated eggs) anyway. So Terrence is completely normal - well, except that he's telepathic.
The Doctor Who Expanded UniverseEighth Doctor Adventures novel Interference introduces a whole society of these. See, when one of them dies, a new copy is created based on what those who knew them remember about them. (Side-effects include infertility.) This seems to be a surprisingly accurate process, as when one of the Doctor's companions gets lost and ends up joining them, he's still vaguely recognizable several iterations later, so the Doctor puts him back to the way he was before he got lost. He handles it quite well... for a while. Eventually, Loss of Identity-based angst, Heroic BSOD, and referring to himself as "it" ensues. He's also quite disappointed to discover he's not even immortal. Indeed, he's basically unchanged except for the fact his dreams are excessively normal and he has a new knack for anagrams and crossword puzzles, and is entirely indistinguishable from a normal human.
The Magic: The Gathering books feature these as good (The Metathran), and bad (Phyrexian Sleeper Agents). The Sleepers had a more frightening creation process, by far. And the scariest bit about the Sleepers is some don't even know they are agents. One particular Sleeper from TimeStreams basically tested the characters and us in the matter of just to what measure a nonhuman is, being portrayed alongside Karn, future main character, and in the end, Karn (a silver golem) was more human than many of the human (or human-looking) characters.
In a short story about a man who decides to create an artificial human, he brings his creation to the city leader. The leader commends his effort but points out the flaws, such as lack of aging and the skin's inability to tan. He then shows the inventor an old video of a young boy and a group of old scientists. He reveals that they are the last true humans. He is that boy, the first artificial human. Unlike the flawed creation, he can do all the things real humans can. Realizing that everyone he knows, including himself, is an artificial human, the protagonist is shocked. The leader then proceeds to wipe his memory of the meeting, so that he can continue living in blissful ignorance.
The wizard protagonist of Jorge Luis Borges's "The Circular Ruins" manages with the help of the fire god to create an artificial human. In the end it turns out he's an illusion as well.
The misnamed "androids" of Robert Silverberg's Tower of Glass. They're visually distinguished from "normal humans" (whom they call "womb-born", and themselves "vat-born") by red skin and lack of body hair.
In Azure Bonds, Alias is revealed to be this, and spends the rest of the novel doubting she has a soul and feeling guilty that her friends have risked their lives to help a soulless automaton. Her friends, of course, think this is ridiculous, since she obviously has a soul; one of them can even ''see'' it. She feels better at the end.
The 'support units' in Alex Scarrow's Timeriders series. They are grown from cloned tissue, deliberately given the appropriate genetic makeup for up to 700% human strength, superior speed and reflexes ... and a brain the size of a walnut. To be fair, they also have an incredibly powerful supercomputer hooked up to it. The first we meet, a male, is frequently described as 'an ox of a man', and Maddy wanted to name him after Arnold Schwarznegger for a reason. The second, a female called Becks, it much more slender, but muscled like a gymnast. Aside from being seven feet tall and laden with more muscles than is strictly fair, the pair go from completely bald (after 'birth') to having fairly ordinary dark hair and grey eyes. In fact, aside from her robotic coldness, quiet demeanour, and artificial speech pattern, you be forgiven for thinking that Becks was (an unnaturally beautiful, which she capitalises on at more than one point) human woman. They are flesh-and-bone rather than metal simply because it is better at learning and better at repairing itself on the field (flesh heals better than steel, at any rate). There are only two problems; they can't easily gauge emotional inflexions like sarcasm, and they find it confusing and problematic to make a decision. the main three characters are later revealed to be more emotional, spontaneous and intuitive, but weaker, versions of the same.
Walter M. Miller's novella Conditionally Human is about this. Twenty Minutes into the Future people are organized into eugenic classes. Class C, not allowed to have children at all, is a niche market for the "neutroids" — genetically modified chimpanzees who look like human children. But they are legally pets. They are bought and sold, stored in kennels and quite frequently euthanized. The original story (scroll down) is not for the squeamish.
In Divine Blood the Gods and Demons each use include artificial people as a normal sort of reproduction. The Gods call these homonculi and the Demons don't have a specific word for it considering it just another way of being born. Despite the fact that Demons care less about the origin, there are more homonculi Gods than there are Demons. Humans have recently looked into cloning, but the first known clone died at six years old after a long history of medical problems. Cloning people has been banned until the reasons behind this have been determined.
The most advanced models of Cylons on Battlestar Galactica are biologically human to the point that they can mate with humans and produce offspring, and can only be readily identified as non-human by exposing them to certain exotic types of radiation. Some of them even fool themselves.
Caprica reveals that realistic humanoid (but not biological) Cylons could have existed 50 years ago (the accidental prototype was a Replacement Goldfish for a scientist's daughter), but their creators ultimately chose the "toaster" design because the realistic androids were too unsettling.
Farscape plays with this trope on a number of occasions. Played straight, the Scarrens have "bioloids" that they mostly use as Evil Twin duplicates. Sikozu is also revealed to be a kind of bioloid.
Buffy's sister Dawn started out "life" as the Key to all dimensions, but was given a human form based on the Summers gene template and inserted into Buffy's family so that Buffy would protect the Key without question. A fake life-history was created for her and magically inserted into reality to facilitate this.
Cameron is the most realistic Terminator ever made, capable of crying, eating and even occasional humor. Though often called a Robot Girl, she'll point out that she's a cyborg; living flesh over a metal endoskeleton. Calling her a "very scary robot" has been known to bother her...
Data from Star Trek: The Next Generation is one of these who strives to Become a Real Boy. He has real hair that grows and needs shaving, his body mimics human breathing patterns, his positronic brain can get "drunk" from the same intoxicating particles as everyone else's. Data is so physically humanlike, in fact, that he can be considered an artifical life-form as much as he can be considered an android.
He always seeks to understand humanity but there are some episodes where becoming fully human tempts him (First Contact) and other episodes where he considers his unique being to have added to the substance of the universe (see "Measure of a Man")
The Vorta and Jem'Hadar of Star Trek: Deep Space Nine. No, they are not Artificial Humans, just Artificial Humanoids. Keeping that distinction in mind, they completely fit the trope: from their fanatical loyalty to their creators, to their utter lack of aesthetic sense.
The replicators in Stargate Atlantis create fully human clones of Shepherd's team using nanites. Eventually, the subset of replicators who wish to ascend decide that creating human bodies is their only way to do so.
The Doctor Who episodes "The Rebel Flesh" and "The Almost People" featured a very real version of this. They are clones of the originals created by a jelly-like substance.
The spin-off The Sarah Jane Adventures has regular character Luke, who was biotechnologically created in the show's first episode by an invading alien race who wanted to use him as a lab rat to study human biology.
A Greek myth tells the story of Pygmalion, a man who shunned real-life women but craved that his beautiful sculpture of one would come to life. He loved it so much that he prayed to Venus/Aphrodite, the goddess of Love, to grant him that wish. After he kissed the ivory-carved statue's lips, Venus worked her magic and it came to life. This is seen as a literal "Breath of Life".
Pandora in Greek myth was a sculpture that the Gods made and brought to life.
The Bible, Book of Genesis: The story of Adam and Eve, with two variants: Both being made from clay, or Adam being made from clay, then Eve from his rib.
Mortasheen plays with this with the creature Lester. These creatures were designed by the monstrous citizens of Mortasheen city to be able to perfectly mimic and infiltrate humans to monitor their natural behavior and harvest them for "research". Unfortunately, they weren't very good at making convincing humans, and it landed so far in the Uncanny Valley that, though the monsters thought it looked like a normal human, the humans were too freaked out for it to be of any use at infiltration. So, now it's only used for infiltrating monsters.
Playing this straighter is the Shade player race, who are sillicon-based solar-powered constructs made for labor, which happen to look like Shadow People . Shades who move up in the ranks tend to trade in for something more... organic.
A few advanced servitors are like this in Warhammer 40000, and there's at least one case of an Adeptus Mechanicus adept deliberately seeking to become one.
The Adeptus Mechnicus worship technology - if they can replace their bodies with tech, they will - Magos Geard Bure from the Eisenhorn series is basically a brain and a central nervous system encased in a metal body. They love Mundane Utility - Bure has no legs, just antigrav projectors. Another one, Dark Magos Deltrian from the Night Lords series is a metal skeleton with a preserved brain. The most revered and ancient Tech Priests can actually replace their physical bodies entirely by transferring their consciousness to artificial crystals. A typical techpriest.◊
And from the same universe, we have the fetches of Changeling The Lost, fake humans made by The Fair Folk to cover up their abductions. They're usually made from whatever stray garbage seems appropriate and a piece of the abductee's soul. Many of them, though not all, believe themselves to be the person they're meant to replace, but always seem to lack at least one feature (positive or negative) that went into the character of their template. Occasionally they are complete psychos.
Eclipse Phase's Pod morphs — short for "pod people", since they are assembled out of vat-grown limbs and organs and equipped with a computer brain.
Actually, all biomorphs (except flats and splicers) probably qualify as Artificial Humans, given that they are all gene-designed by various groups and grown in artificial wombs.
Guidelines for designing your own bioroids - and infinite other forms of gengineered life - reappear in GURPS: Bio Tech.
Alchemical Exalted serve as this, being humans made from clay, brass and Magical Material, and who require food and drink to function properly (but cannot starve), although sufficient Charm implants can give them form more reminiscent of conventional Robots, and they eventually turn into Humongous Mecha and then cities.
The Realians from the Xenosaga TV and game series. In addition, Ziggy is a Cyborg relic from the past.
Additionally, KOS-MOS and particularly Telos, since she was built from the preserved body of Mary Magdelene. Yes, that Mary.
Rubedo, Albedo, Nigredo, and Citrine from the Xenosaga videogame series are all variant clones of their creator, Dr. Dmitri Yuriev. There were others created that collectively formed a sort of "hive mind", but they were all destroyed during the Miltia Incident.
In Xenogears the heroes find out that the species on the planet are not humans. Humans died out long ago (well, humanity's fate in Xenogears is ambiguous at best), and what's left evolved from the biological parts of their technology.
In Xenogears, Ramsus Kahran is a clone of Emperor Cain. And he has some issues with it....
The Phantasy Star series is rife with artificial humans, the best example of this being the Newmans, starting with Nei in Phantasy Star II (described as a result of combining human and biomonster DNA), continuing with Rika in Phantasy Star IV, and eventually becoming an entire race in Phantasy Star Online. The series also has various androids and cyborgs, such as Wren, Mieu, and Demi in the original series, and a race of humanoid robots called CAS Ts introduced in PSO. Phantasy Star Universe also introduced yet another race of artificial humans called Beasts.
Safiya in Neverwinter Nights 2 Mask of the Betrayer is a splinter of a very, very old Red Wizard's personality
Not so: one event in Advance puts her in harm's way when she's struck by Kazuya Ryuuzaki and Domom Kasshu and simply shrugs it off. Both men, who're exceptional martial artists, state they hit her vitals, which would outright kill a person.
In Wild ARMs (original and ACF version), the protagonist Rudy is an android/artificial human made from technology similar to that of the Metal Demons. He is a "Holmcross", given the alchemy refs, is clearly a transliteration for "Homunculus".
The other games had their share of Artificial Humans too. Wild Arms 3 had Jet, who was similar to the first game's example, only he was created to test the theory of Filgaia as a lifeform, and Wild Arms 2 and 4 had Cyborgs in the characters of Kanon and Balgaine.
In the Kingdom Hearts games, Organization XIII member Vexen builds several Replicas; humanoid "puppets" made for various purposes. Two recurring traits among said Replicas are the ability to drain power from other people, and a tendency towards feeling incomplete or "borrowed".
In Albion, NED's primary means of communication is using an android body to interact with his crew. He even has an entire army of them prepared to slaughter everyone on board should they rebel.
The Observers and Trackers from Infinite Space are created by the Overlords to watch the progress of humankind in fulfilling their role to stabilize the universe. Five characters are identified as them throughout the game (Yuri, Kira, Valantin, Taranis, and Bogd), although given the story, there are probably more of them.
Deus Exthe Denton 'brothers' are revealed to be completely artificially engineered.
In the Mega Man Legends games, it's revealed that all the humans you see in the game are Artificial Humans made by the main character's creator, and the main character himself is either an Artificial Human or a Ridiculously Human Robot created by the leader of the original humans. Then the game stops being serious and gets nice and zany again for the post-credits ending.
In Nie R, as revealed quite late, it turns out that Nier and almost every other human(except Emil and the Twins) are Replicants, clones of people who were made into Gestalts intended to serve as their vessels after the purification of the world. Unfortunately for the plan, they developed minds of their own.
Arcueid in Tsukihime is an artificial human True Ancestor, created for the purpose of killing Demon Lords and Dead Apostles. She doesn't get all angsty because she doesn't seem to possess that emotion.
Wasn't Arcuied only "created" to hunt Dead Apostles in the sense that she was carefully raised from birth to be a killing machine, rather than actually created as an artificial being? Now her Dead Apostle "sister" Altrouge on the other hand...
It's kinda tricky. True Ancestors as a whole were created by Gaia (and corrupted by Brunestead, the Type of the Crimson Moon) as an Artificial Type (A planet's Ultimate One) in response to humanity, and probably aren't even born naturally. It seems that Arcueid was "created" to hunt Demon Lords in both senses; she was trained to do so, without any other unnecessary education, but it also seems that the True Ancestors guided her creation, causing her to be a perfect vessel for the Crimson Moon, something that the original Crimson Moon couldn't even manage himself.
Finally, also in Fate/stay night's Heaven's Feel scenario, Shirou is reduced to this in the True ending.
Almost all the Servants with the notable exception of Saber are basically Artificial Themselves, created by taking a copy of their minds and putting it in a body created by the Holy Grail. And then there's false Assassin, who is an Artificial Servant, created in the form of a Hero that never actually existed in the world of Fate/stay night.
All furniture in Umineko No Naku Koro Ni is supposed to be some variant of this, although with Shannon, Kanon and Genji, this turns out not to be the case. In fact, the person who created the term "furniture" in-universe was Yasu, the original personality of Shannon, Kanon and Beatrice (III), who sees him/herself as less than human due to his/her mutilated sexual organs and inability to have sex as a result.
Tanya, the android love interest from Bionic Heart has a metal skeleton, but she has artificial organs identical to a human’s. They don’t function, however. But Tanya does have a working human brain that is the cause of her memories.
In Artifice, android soldier Deacon looks and for the most part acts completely human (even though he rejects the term) and, in the opening scene, two security guards debate whether he deserves the title of being called an "Artificial Person".
Stephanie Rossum is the tall, blonde, adorable Robot Girl in Groovy Kinda. She's got a Farrah Fawcett hairdo and she loves pudding and books with pictures of kittens. Stephanie also smokes cigarettes, which she can light with her finger.
Since Momo got her new chassis, she's gone from an animesque doll-like robot to being effectively an Artificial Person. In this comic, she's human-looking enough for Padma to mistake her for Marten's little sister, and she now has a job as a library assistant. And even the non-human-looking AnthroPCs seem to have sexual and emotional urges and a sense of humour, so they're not very robot-like.
Belphoebe of the Whateley Universe. A cloned body based on Jobe's secret drow transform serum. A mental copy of Belphegor is (accidentally) imprinted onto the body, and it wakes up. It's adapting quite nicely so far.
Imca is not natural, but rather artificially created, and while mostly squishy and quite like a normal gijinka, even if she is synthetic, does have some electrical bits in her head.
Mina, a protosapien clone, is created in an artificial womb as a supersoldier. Her cybernetics inside her are biomechanical which grows alongside her body.
Some Transformers late in the original line made use of Pretender technology, which involved fleshy outer shells. Those with human shells, therefore, could shrink down and blend in with humans. This skips the Become a Real Boy step, though, as Transformers are Mechanical Lifeforms, and thus start off sentient and sapient.
the characters in Beast Wars, who took the Pretender technology one step further to become Hollywood Cyborgs. Even before the line between "tech" and "organic" became blurred in the series, the creators emphasized that the robots' pseudo-organic "beast modes" were "fully functional"... take that as you will.
In Transformers Animated, it turns out that Sari was a protoform, which is what a Transformer is before it has scanned anything for the first time. She scanned Isaac Sumdac, basically making him her Dad.
Cyber 6 in Cybersix; she sleeps, daydreams, eats, and for the most part doesn't even have any great trouble in socializing.
Cobra "synthoids" in G.I. Joe could perfectly mimic real people and were key to several episodes where a Faked Rip Van Winkle or Body Snatcher plot was in effect. They were apparently organic in nature, being constructed of a grey goopy matter called "Pseudoplasm" which they would terrifyingly revert back into by melting if killed or self-destructed.
The Synthoid technology was also put into use in an episode of Transformers, in which Rodimus Prime, Arcee and Ultra Magnus had their minds transferred into synthetic human bodies. Luckily for the Moral Guardians, these came with automatic underwear.
Aelita was thought to be one of these (specifically, an AI) for two seasons, until it was revealed that she was, in fact, human, not to mention the daughter of the supercomputer's creator.
XANA uses "Specters" in his attacks all the time, whether polymorphic (shape-shifting) or not. They are easily synthesized using the supercomputer, and usually look like one of the heroes or someone close to them. They're generally mindless, and can be used to coerce, trick, or attack the heroes.
These clones can also be utilized by the heroes themselves. Only two have been cloned this way:Jérémie and William. Jérémie's clone substituted for the original while he worked on several programs for Lyoko. Clone!William replaced his real world counterpart for several months while the real one was trapped in Lyoko. Unfortunately, while these clones were pretty much benign and harmless (unless possessed by XANA, which both have been), they have drastically different personalities than their originals: Jérémie's clone is a bold womanizer, while William's clone is profoundly naive and stupid.
From Young Justice, Red Tornado and his siblings, Red Torpedo, Red Inferno, and Red Volcano. Red Torpedo and Red Inferno forgot they were androids, leading to their destruction in the line of hero work. Red Tornado was subsequently programmed to remember he was an android, but he eventually begins to develop human emotions such as caring for others anyways.
Not to mention Superboy, a clone of superman combined with Lex Luthor DNA to replace him if the need ever arises. Also Red Arrow is a clone.