Aquaman's Arch Enemy spot is shared between his brother Orm, aka Ocean Master, and Black Manta. Depending on continuity the reasons behind Arthur and Orm's rivalry differs. But it usually revolves around the two brothers fighting over who is more fit to lead Atlantis. With Black Manta, their relationship is just full of mutual hatred.
Azrael: Jean-Paul Valley had two; Carleton Lehah and Nicholas Scratch. Averted for Michael Lane, who hasn't been active nearly long enough in order to get a real archenemy, though the Crusader came real close.
Aztek had the Lizard King, who murdered his girlfriend, and Mageddon, the evil god he is destined to defeat.
During her Pre-Crisis career, Barbara had Killer Moth. During her time as Oracle, Barbara had the Calculator and James Gordon Jr.
Cassandra and Stephanie both have their Arch Nemesis Dads, David Cain and Cluemaster. Cassandra can also count her mother, Lady Shiva, as one, though their relationship is more complex than the typical archenemy dynamic.
The Joker is Batman's Arch-Enemy. He's the One, he's the best. His insanity and chaotic nature are the complete opposite of Batman's rigidly, even obsessively ordered intelligence. Though these (intelligence and obsession) are also their similarities. Both were shaped by great tragedy and loss (at least in the Joker's most commonly accepted origin story). Many people have said that Batman is just as insane as The Joker, he just manifests it in a different and more positive way and keeps control over it. The Joker himself has pointed this out numerous times and in many adaptations.
Rā's al Ghūl has a great deal of respect for Batman, may be even more dangerous, and a far larger scale threat, than the Joker, and is the father of one of Bruce's main love interests and his son's grandfather. If not the Arch Enemy, Ra's is definitely the main Big Bad of Batman's enemies.
Two-Face: Batman sees him, with good cause, as his greatest failure, a point that Two-Face enjoys rubbing in. Every single one of the Robins has also had a reason to put them high on their hit lists. He beat Dick Grayson within an inch of his life on one of his first outings as Robin (handing him his first defeat in the process), orchestrated the murders of Jason Todd's parents, and in "A Lonely Place of Dying" nearly killed Tim Drake in one of his earliest solo missions as Robin, with Dick having to save him. While the individual Robins have their own enemies, Two-Face is easily the archenemy of the collective Robin identity.
As far as honorable mentions go, Bane, The Scarecrow, and The Riddler also deserve a mention. All three are highly effective Shadow Archetypes of Batman who have pushed him through some severe trials. While they are overshadowed as Archenemy material by the above three, someadaptationshave played up their mutual hostility with Batman and standing in his Rogues gallery. In the case of Bane, this also happened in the DC Rebirth Batman comics when he decides to get revenge on Batman, culminating in his brutal murder of Alfred Pennyworth, surrogate father of Batman.
Harvey Bullock has the Mad Hatter, who orchestrated the Gotham High School bombing that ended up being Bullock's one unsolved case that haunted him years.
Black Canary has Lady Shiva and White Canary. Her mother, the original Black Canary, had the Wizard.
Black Lightning had Tobias Whale, the gangster who ruined his neighbourhood, targeted his students, and convinced him to get into crime fighting in the first place. Whale for his part hated both Black Lightning and his civilian identity of Jefferson Pierce, and went out of his way to dispose of them both.
Black Orchid had Carl Thorne and Mr. Sterling. Later, the third Black Orchid had her predecessor, Flora Black, after she went rogue.
Blue Beetle has Carapax. Carapax is absolutely determined to destroy Beetle and everything he stands for, regardless of who is holding the identity; he started out fighting Ted, but battled Jaime as well simply because he was using the title Blue Beetle. Even death couldn't keep him from coming back to torment Beetle.
Jaime Reyes later developed another contender for archenemy title in the form of Black Beetle, an Evil Counterpart who also uses Reach tech and is motivated by his sister's death, which he blames on the Blue Beetle, thus making their conflict personal.
After becoming evil, being killed, and then brought back to life, Maxwell Lord has become the Arch Enemy to Booster Gold. Black Beetle is this in Booster Gold's own series.
Blue Devil has Bolt. He had the demon Nebiros, until he was killed in Day of Judgment.
Catwoman had Black Mask (the original version) as her arch-enemy in her early-2000s series. In a Darker and Edgier twist, she ended up murdering him after he tried to fridge her friends and relatives once too often.
The Prescence has a few. Decreator the Anti-God is one, being the first shadow cast by The Presence's light. Another would be Lucifer obviously though played with as the relationship is less enemy and more a complicated one between a distant father and a rebellious prideful son.
Kismet had Imperiex and Dominus.
The Monitor and the Anti-Monitor.
Nix Uotan, a.k.a. the Judge of All Evil, had his father, Dax Nova, a.k.a. Mandrakk the Dark Monitor.
Cyclone has T.O. Morrow, who kidnapped and experimented on Cyclone at a young age. Morrow infected Cyclone with nanobytes that left her with superpowers.
Darkseid is the biggest bad of the DC Universe and is the archfoe of the Justice League, New Genesis, and the DCU itself. On the personal level, he's also the archenemy of his son, Orion, and of New Genesis' leader Highfather, and has pursued lengthy vendettas against Mister Miracle, Superman, and Wonder Woman, to name only a few. Essentially, the moment Darkseid shows up, all other considerations, and all other archenmities go out the window.
Orion also has Kalibak and Desaad. Kalibak is Darkseid's loyal son, and is resentful that Darkseid favors Orion over him. Desaad has concocted multiple schemes to kill Orion, and Orion eventually vows to kill Desaad after Desaad makes several attempts on Orion's life and masterminds an attack on New Genesis.
Mister Miracle and Big Barda have Granny Goodness.
Doctor Fate II (Eric and Linda Strauss) had Anti-Fate and Typhon.
Doctor Fate III (Inza Nelson) had T'Giian.
Fate (Jared Stevens) had Talbot Cantrip and Pharaoh.
Doctor Fate IV (Hector Hall) had Mordru and the Curse.
Doctor Fate V (Kent V. Nelson) had Eclipso and Negal.
The Earth-2 Doctor Fate (Khalid Ben-Hassin) has his Earth's version of Wotan.
The Doom Patrol has the Brotherhood of Evil. Their respective leaders, the Chief and the Brain also have one another.
Etrigan has Morgan le Fey and Klarion the Witch Boy.
Firestorm has Killer Frost, Multiplex, and Deathstorm.
The Flash. This varies from era to era since there are multiple Flashes.
In the Golden Age comics, Jay Garrick (Flash I) had the Thinker, who appeared more often than any other villain. The two would eventually become friends in old age, but by that point, Edward Clariss AKA The Rival, Jay's own Reverse-Flash, had been introduced.
Barry Allen (Flash II) has had a few. In the Silver Age, it was Gorilla Grodd, who was the one exception in his roster of Harmless Villain antagonists. In the Bronze Age, it was Eobard Thawne AKA the Reverse-Flash and his repeated attempts to outright steal his foe's life, and who eventually killed his wife. In the Modern Age, after Barry's return, Geoff Johns had promoted Captain Cold to leader of the rogues — in the Silver Age it was usually the original Mirror Master or an outside villain in this role — and brought the Rogues back into prominence. Cold specifically considers Barry to be his Flash nemesis (he's fought all four of them, and in the Modern Age mostly Wally). Later on, it was cemented that Thawne was Barry's archnemesis because he killed Barry's mother and is the most dangerous of Barry's foes.
Wally West (Flash III) in the Modern Age had Vandal Savage at first, and later the acclaimed Mark Waid run boosted Abra Kadabra to this role by making that villain much Darker and Edgier and a much more recurring threat in Wally's life. Later on, Geoff Johns also contributed Zoom/Reverse-Flash II as a contender for the role, an Evil Former Friend of Wally's who caused Wally's wife to miscarry and is also a villain he feels responsible for creating. In the aftermath of DC Rebirth Kadabra tries to rekindle his rivalry with Wally by taking credit for Wally's disappearance, although he's thrown into the timestream at the end of the arc, and later down the line, Zolomon was reintroduced and revealed to know the location of Wally's missing children and cemented himself as this too.
Bart Allen (Flash IV) had Thaddeus Thawne AKA Inertia, his evil clone who sought to have a family like Bart. Another contender would be Superboy Prime, who hates and downright fears Bart.
Jesse Quick/Liberty Belle II had Baroness Blitzkrieg.
Max Mercury had Savitar. Both are old speedsters who interpret the Speed Force differently: Max trains those who can tap into it while Savitar runs an evilc cult around its worship.
Merlyn is considered Green Arrow's arch-enemy. Due to both being skilled archers on opposite sides of the law. Count Vertigo can also be seen as this.
The role of Roy Harper's arch-enemy can be given to Cheshire, which also falls into Dating Catwoman due to their former relationship and that she's the mother of his daughter. She's consistently proven that, whatever lingering feelings she might have for Roy or their child, she'll do anything to get them out of the picture if they prove a detriment to her freedom.
Golden Age Lantern Alan Scott has Solomon Grundy, who menaced his hometown more than any other villain, and whose wood-infused body was highly resistant to Scott's ring. The New 52's Earth 2 comic has brought this rivalry back in a big way.
Sinestro is Hal Jordan's archenemy (and Evil Mentor depending on the continuity); similarly, the Green Lantern Corps treat the Sinestro Corps as their most dangerous opposing organization. Cyborg Superman and Hector Hammond could also count. While Sinestro is his most frequent and prominent enemy, no one hit Hal harder than Cyborg Superman who destroyed Coast city. This resulted in Hal falling victim to Parallax's possession.
When Major Force isn't ruining Captain Atom's life, he's probably ruining Guy Gardener's or Kyle Rayner's. Specifically, Force began the Stuffed into the Fridge trope by killing Kyle's girlfriend and... y'know.
John Stewart has Fatality, who blamed John for the destruction of her homeworld and killed his girlfriend in retaliation.
The Guardians of the Universe have Krona.
The Entity has Nekron.
Ion has Parallax, as the personifications of Willpower and Fear respectively.
Jade has Fatality.
Kilowog has Arkillo.
Mogo has Ranx, a moon-sized living city who is prophesied to destroy Mogo one day. In the Sinestro Corps War, he tried and failed.
Saint Walker has Atrocitus and Larfleeze.
Harley Quinn has the vigilante Thorn in her original solo series. In the New 52, she has Zena Bendemova and the Red Tool.
Hawkman and Hawkgirl have Gentleman Ghost, the Shadow Thief, Hath-Set, and Byth Rok.
The Huntress originally had Omerta the Silencer, Stephen Mandragora, and Santo Cassamento, who are all responsible for the murder of the Bertinellis, driving Helena Bertinelli to become the Huntress. However, Helena killed all three of them in vengeance. More recently, Huntress has grudges against the Penguin, who betrayed the Birds of Prey and severely injured two of her allies, and the Scarecrow, who used fear gas to make her fight Catwoman.
Katana had Takeo Yamashiro, who murdered her husband and two children because she rejected his advances.
Jimmy Olsen gets his own arch-enemy in the Action Comics backup strip: a young Lexcorp executive called Sebastian Mallory. He aknowledges that "Superman's Pal vs Lex Luthor's protege" might seem a bit obvious, but they really do hate each other.
Johnny Sorrow is this for the entire Justice Society of America. Originally he only had a beef with Sandman, but after Sandy joined up with the Society, Johnny came to hate all of them with equal, massive fury. Now he's not only one of their most personal foes, but he's one of the few villains who's always gunning for the entire team at once.
Atom Smasher had Kobra and Extant. Kobra who orchestrated a plane crash that killed his mother. Extant murdered Atom Smasher's godfather, Al Pratt, and Atom Smasher later returned the favor by killing Extant in the aforementioned plane crash, which erased his mother's death in the process.
Damage has Baron Blitzkrieg.
Hourman I had Psycho-Pirate, Doctor Togg, Doctor Iker, and Doctor Darrk.
Hourman II had Eclipso, the Wizard, and Extant.
Hourman III had Amazo.
Stargirl's arch foe from is Shiv from Blue Valley. Shiv was a Foil to Courtney in that, while Courtney was the stepdaughter of an established superhero (Pat Dugan, a.k.a. S.T.R.I.P.E.) and initially became a hero to piss him off, Shiv is the biological daughter of an established supervillain (the Dragon King) and became a villain to make her father proud. However, Shiv fell into limbo for a few years after her last fight with Courtney. The next time they fought Courtney joked about how long it'd been since she saw Shiv.
The first Doctor Mid-Nite had the Golden-Age Doctor Light and the Shadower.
The second Doctor Mid-Nite had the Ultra-Humanite, Roulette, and Gog.
The Legion of Super-Heroes has three: Mordru, the Fatal Five, and the Legion of Super-Villains. The Fatal Five probably win the title for showing up the most often, but the L.S.V. has Lightning Lad's personal arch enemy (and older brother) Lightning Lord, and Mordru is certainly the most powerful of the three. Pre-Crisis the title would have gone to the Time-Trapper.
Blok has Mordru.
Brainiac 5 has Computo.
Bouncing Boy has the Hunter.
Chameleon Boy has Chameleon Chief and Composite Man.
Cosmic Boy has Cosmic King.
Dream Girl has the Emerald Empress.
Element Lad has Roxxas.
Ferro Lad has the Sun-Eater.
Karate Kid and Princess Projectra have Nemesis Kid.
The Martian Manhunter has had several contenders over the years including Commander Blanx and his expy (and J'onn's Evil Twin) Malefic. The best example, however, may well be Galactic Conqueror and walking engine of destruction, Despero. While Despero is usually a Justice League calibre threat, J'onn is always the one he attacks first, and he takes a perverse delight in forcing the Martian to telepathically relive the destruction of Mars. At one point, Despero went so far as to Mind Rape J'onn into believing he was on a Mars that hadn't been destroyed by Blanx and/or Malefic...only to then invade the dream and personally slaughter the psychic constructs of J'onn's family that he had created. J'onn hates Despero about as much as he hates anyone, and is usually the JLA member who ends up having to put the crazed being down at the end of his rampages.
The Question had Reverend Jeremiah Hatch, a corrupt preacher and the power behind the throne in Hub City.
While Green LanternRebirth and Blackest Night initially pegged Parallax as the Arch Enemy of The Spectre, it seems that the Spectre's true nemesis is actually Butcher the Rage Entity. The Spectre exists to punish murderers, and Butcher is apparently the homicidal spawn of the first murder — the embodiment of murderous rage. Spectre also has Eclipso, his predecessor as the personification of God's Wrath who turned evil, Azmodus, a demon who seduced the Spectre's first human host, and Zor, another spirit wandering the Earth, who chose to spread evil instead of fight it.
In the Robin comics of the 90's, King Snake (the father of Bane) and then Ulysses "The General" Armstrong filled this role for Tim Drake. As Red Robin, Drake had The General again for a while (this time masquerading as Anarky).
The Shade had Simon Culp for more than a century, until he was finally killed.
Shazam: Things get interesting here, and a little complicated. Billy/Captain Marvel has usually considered Black Adam or Dr. Sivana to be his worst enemy. Freddy/Captain Marvel Jr. considers Captain Nazi, who killed his grandfather, to be his worst enemy. Mary Marvel has Georgia Sivana. However, the archenemy of the Marvel family as a whole, and certainly the most dangerous of their foes, is telepathic Venusian worm, Mister Mind, who destroyed their hometown, brainwashed their friends, and murdered their cousin. Whenever Mind shows up, you can bet that the storyline will get darker, and Billy, Mary, and Freddy alike will take it very personally.
Shazam the Wizard has Blaze and Satanus, his Antagonistic Offspring who are responsible for corrupting Black Adam in the first place.
Osiris, the brother-in-law of Black Adam, has Sobek.
Starman had the Mist. Their respective children, who shared the same codenames, became archenemies too.
Lex Luthor is Superman's ultimate Arch Enemy and typically uses his brain against the Man of Steel's brawn, carefully avoiding any actions that could make Superman be justified in attacking him. To the point where only the muckraking Clark Kent, not Superman, can even put a scratch on Luthor. In Infinite Crisis, Alexander Luthor Jr. (son of a heroic alternate universe Luthor) eventually becomes convinced that one of the few things every universe has in common is that the resident Luthor and Superman (or Superman analogue) will always be archenemies.
After Luthor, Brainiac comes in a close second, being one of the oldest villains in the rogues gallery, and certainly one of the most evil. He can match Superman blow-for-blow, shows up constantly, is feared by all Krytponians regularly endangers the world or even the multiverse, holds a Kryptonian city hostage, and once killed Jonathan Kent. As one writer pointed out, he's the alien Superman isn't, an evil otherworldy invader instead of a messianic refugee.
General Zod is the Arch Enemy of Superman's father Jor-El, the one responsible for stopping his coup and imprisoning him in the Phantom Zone, with Superman inheriting the grudge. Following Superman's defeat of Zod in Last Son and the events of New Krypton, the rivalry turns very personal for the both of them, and along with Luthor and Brainiac, he's one of the few beings that Superman genuinely hates.
Kal-L, the Golden Age Superman, has Alexei Luthor, Lex's Eastern European Earth-2 counterpart.
Superboy has King Shark, Knockout, and Match from his solo series.
Post-Crisis Supergirl has Reactron. A lecherous, bullying thug, Benjamin Krullen craved for getting even at Kara because she had the gall to kick his butt when he attacked her without provocation. Over the course of both her solo series and the New Krypton crossover, the two clashed repeatedly, leading to Reactron's murder of Supergirl's father, her mother Alura's Cold-Blooded Torture of Reactron upon his capture, and the eventual destruction of New Krypton when Reactron blew up himself, the planet, and Kara's mother. For both of them the conflict was always personal. Needless to say, Supergirl hates him, and a hallucination looking like Reactron is enough to send her into a murderous rage.
Post-Flashpoint Supergirl has the Worldkillers whom she despises because she's a survivor of a dead world and they're Kryptonian biological weapons designed to conquer worlds and slay alien species. It doesn't help that she suspects her father Zor-El was involved in their creation. In Red Daughter of Krypton she explains why stopping them is personal to her.
Supergirl: How could anyone make it their mission in life to murder whole worlds? Can you imagine what an abomination that is to an orphan from a dead planet? [...] This world-killing stuff... it hits a nerve. It makes me furious, and the ring just fans the flame!
Deathstroke the Terminator is Robin/Nightwing's Arch Enemy. Of all the Titans, Slade hated Dick Grayson the most. Whenever Slade and Grayson were in the same fight, regardless of how many others were involved, they nearly always went after each other. This animosity was ramped up immensely when Slade, as part of the Secret Society of Super Villains, orchestrated the destruction of Blüdhaven, Nightwing's "Gotham" so to speak, with the nuclear waste monster Chemo, when he cybernetically hijacked Damian Wayne's body in an attempt to kill Grayson, and when he stole Dick's money for Joker during the events of Joker War. Deathstroke also harbors a grudge against Grayson for "stealing his kids" from him. Deathstroke is also to the Teen Titans as a whole. Now the Titans have gone through tons of Big Bads, and let's face it, Slade isn't the biggest or baddest. But he is the most persistent and most personal enemy the team has ever faced.
Trigon to his daughter, Raven. He'd also finish in second place for the team as a whole, since besides Slade, there's nobody the Titans hate or fear more than Trigon, and nobody period who outdoes him in threat level.
Starfire has her sister Blackfire, though they're on better terms now.
Miss Martian has Sun Girl. Sun Girl claims Miss Martian will bring doom to the future that she hails from, so she must kill her to prevent it from happening. But she also claims that she and Inertia have also made Miss Martian their slave to torment. It's implied that because of whatever Miss Martian did, White Martians in the future were now treated as slaves, and Deborah was more or less Miss Martian's owner.
Rose Wilson despises her father, Deathstroke, for orchestrating her adopted family's murder and for implanting kryptonite in her body, which would have eventually killed her if Nightwing hadn't warned her in time.
Vandal Savage is primarily this to the Immortal Man and later to the Resurrection Man. He'd also finish very highly on the JLA and JSA's hit lists, and has, over the course of his immortal life, pursued vendettas against Green Lantern, Flash, Damage, the Ray, and Rip Hunter, to name only a few.
Wonder Woman's is generally Cheetah or Circe, depending on who's writing. Ares gets in on the act too. He was, after all, her original Golden Age arch enemy, and is the biggest bad in her rogues gallery. As of Flashpoint Hera may be stepping into the role.
Diana's sister, Donna Troy, gained one in Dark Angel by accident. Dark Angel wanted to get revenge for her defeat by Hippolyta by abducting her daughter and making her live through a thousand lifetimes ending in tragedy. But Donna, who was identical to Diana, was grabbed by mistake. Even after the mix-up was cleared, Dark Angel forgot her beef with Hippolyta and is now focused on making Donna's life as miserable as she can, which is not helped by knowing Dark Angel is the Donna of a dead alternate Earth.
Hippolyta also has Circe, who brainwashed her on multiple occasions. Hippolyta also had Hercules, who once betrayed her trust and raped and enslaved her and her fellow Amazons. Dark Angel also qualifies, since Hippolyta battled her on many occasions.
Artemis had the White Magician, Dalkriig-Hath, and Mister Smyth.
The Watchmen has for the whole collective of superheroes Ozymandias, a former member that wants to save the entire world by destroying some of it. Originally, the Minutemen's archenemy was Moloch the Mystic.
Alpha Flight has the Master of the World and Jerome "Jerry" Jaxon.
Aurora has the Director and Headlok.
Guardian has the Master of the World and Jerome "Jerry" Jaxon.
Marrina has the Master of the World.
Sasquatch has Wild Child and Wendigo.
Shaman has Ranark.
Snowbird has Pestilence.
Vindicator has Scramble.
Angela has Hela, who imprisoned the soul of her lover, Sera.
Ant-Man's is Ultron, the rogue robot he created. Though the villain he's most likely to face by himself is probably Whirlwind. Since Ultron's programming is based on Ant-Man's own thought patterns, this also means that Ant-Man is his own worst enemy. Used to be Egghead...but he died.
Despite this, Ultron is primarily the archenemy of the Avengers as a whole, rather than just Ant-Man personally. Ant-Man does take it personally for the aforementioned reasons, though, so it's definitely an interesting play on the trope because of that. Storylines where the Avengers take on Ultron tend to be some of the most personal and traumatic experiences as well.
Beta Ray Bill at first had Surtur, who destroyed his people, but in later comics it's Galactus. And unlike the other countless billions that have sworn to destroy the Devourer of Worlds, Bill is a genuine threat to him.
Betty Ross shares Hulk's archenemy list, with her hatred of Abomination and the Leader being near as personal as his own.
Meggan had Mad Jim Jaspers has well, because he seperated her from her father permanently by placing them in concentration camps. Meggan also had Sat-Yr-9, who screwed with her relationship with Brian and tried to have her killed.
Captain Mar-Vell had Thanos. Although Thanos did double duty as Adam Warlock's arch enemy, too. And he screwed with the Silver Surfer pretty seriously, too. After arcs like Infinity Gauntlet and other stories on that scale a case could be made that Thanos is the Arch Enemy of the Marvel Universe.
The Living Tribunal had Ereshkigal and Protégé. Ereshkigal was a Devinat Went Mad From The Revelation when she learned about the existence of the Living Tribunal, and devoted her existance to freeing the Multiverse from the Living Tribunal's governance. She eventually accumulated enough power to challenge the Living Tribunal, who agreed to a contest of champions between them once he realized that a battle between the two could destroy the Multiverse. Meanwhile, Protégé managed to copy the powers of the Living Tribunal, nearly usurping its place in Marvel's cosmology before the Living Tribunal defeats and absorbs Protégé to prevent him from endangering all realities again.
Death has Walker.
Eternity has Death and Abraxas.
Infinity has Oblivion.
Lord Chaos and Master Order have the In-Betweener, their nominal servant who keeps defying them.
Bullseye. A Psycho for Hire who typically acts as The Dragon to Kingpin, Bullseye's killed two of Matt Murdock's girlfriends, tried to kill his wife, Milla, and has generally dedicated himself to making Matt's life as hellish as possible; he's also inspired the likes of Lady Bullseye. In return, Matt wants Bullseye dead, and is willing to violate Thou Shalt Not Kill for him in a way he will for nobody else.
The Kingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list, as well as a contender for The Punisher's). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the deuteragonist of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
The Ninja clan known as the Hand collectively fill the third slot on Matt's hit parade. They're among his most persistent enemies, many of his major foes (Elektra, Lady Bullseye, Kingpin) have either worked for them or tried to gain control of them at one point or another, they're the ultimate adversaries of his mentor, Stick, and worst of all, they want Matt to be their new leader. It's hard to get more personal than that.
Originally, as written by Stan Lee, it was the Owl. These days, he's reduced to second-string status; while still dangerous he just doesn't carry the emotional weight that Bullseye, Kingpin, and The Hand do.
Mob boss Phillip Bazin, later replaced by Dargin Bokk, creator of the Darkhawk armor.
And now replaced by Talon and possibly the whole Fraternity of Rapors, real creators of his armor.
Dazzler used to have the Enchantress. Now, its her sister Mortis.
Deadpool has T-Ray, Ajax, Dr. Killbrew, and Black Swan.
As of his 2015 series, Madcap also fills this role. He's even crazier than Wade, has a much better healing factor than Wade, and has a deep personal hatred of Wade after an incident with Thor ended with him merged with Wade's mind (he was the white text box). The experience harmed Madcap in a way he never felt before and left him obsessed with completely destroying Deadpool's life and loved ones. After very nearly killing his daughter and several of his closest friends, Deadpool hated Madcap to an even greater extent than his past arch enemies and people like the Weapon X program and Sabertooth (who Wade believed murdered his past family). By the time Deadpool finally gets rid of Madcap, the latter doesn't mind simply because Wade himself has already managed to completely ruin his own life, with Madcap declaring the actual death he was going to give to Wade's family wholly inferior to the spiritual one Wade himself gave them.
The Defenders have Dormammu, Nebulon, Gorilla-Man, and the Dragon of the Moon.
Moondragon has the Dragon of the Moon.
Nighthawk had Nebulon and the Squadron Sinister.
Valkyrie has the Enchantress, who once trapped her essence inside a soul crystal, kept her there for centuries, and used Valkyrie's superior physical abilities for herself, or to enhance her pawns.
Devil Dinosaur and Moon Boy had Seven-Scars and the Prime Computer.
Hyperion was their arch enemy for the middle of their comic run as the rogue member of their "rivals" weapon X who didn't want to go dimension hopping and just conquer an earth for himself. In fact, his influence was so bad the timebroker ended up having to cut out multiple dimension hopping teams for his meddling, not to mention him killing 2 members of their team and critically injuring 2 others.
Proteus meanwhile found out about the Exiles mission...by possessing longtime member Mimic who was the leader Blink's boyfriend. Proteus ended up messing up the time stream even more for the exiles, and Morph got it bad as well since Proteus possessed his body for an extended period of time too. Once they could defeat him, it was a great relief for all the exiles.
The Falcon shares the Red Skull with Captain America. After all, the Red Skull gave Falcon his powers in a bid to defeat Captain America, only for Falcon to defect to Cap's side help him thwart the Red Skull multiple times. The Red Skull also created the Falcon's "Snap" persona and fake criminal backstory in order to mess with his head and discredit him.
The wrathful vengeance of Doctor Doom will never be sated! Never until the earth runs red with the blood of that accursed REED RICHARDS!!
The rest of the Fantastic Four as well, to a lesser extent. After he crushed Doom's hands, the Thing also jumped pretty high on his list. Doom also has a villainous crush on the Invisible Woman, but also fears her as the team's most powerful member.
Galactus is a close second. Not only were Fantastic Four were the first mortals to defeat and intimidate Galactus, but they also freed Galactus's Herald, the Silver Surfer, from his control.
The Human Torch used to have the Wizard in his solo adventures, but he has since gone on to become an enemy for the team in general.
Uatu the Watcher has Galactus, Aron, and Abraxas.
Doom himself has, other than Reed, Mephisto. Mephisto has possession of his mother's soul, and after he rescued her, Doom is one of the few people to have outright bested Mephisto.
Flash Thompson has Jack O'Lantern and the Crime Master.
The Fabulous Frog-Man is a super zero wearing the Power Armor of his father (Daredevil villain Leap Frog) which he cannot control so he just bounces around aimlessly and sometimes gets lucky. The White Rabbit is a ditzy Harmless Villainess that read too much Alice in Wonderland when she was a little girl and now dresses like a Playboy Bunny and pretends to be a Super Villainess despite having no powers or skills. They became each others arch-enemies because they are so pathetic nobody else would take them seriously.
The Johnny Blaze/Zarathos incarnation of Ghost Rider's Arch Enemy is Mephisto.
The Danny Ketch/Noble Kale incarnation of Ghost Rider's Arch Enemy is Deathwatch.
Gladiator has Vulcan and Xenith.
The Guardians of the Galaxy probably have the most personal hatred of Thanos among any of Marvel's super teams. It's worth noting that over half of it's founding members were already classified as Thanos' arch enemies, while other members later gained very personal reasons to hate the titan. The Universal Church of Truth also ranks high on the list for both Guardians teams. As far as individual members go:
Star-Lord has Mr. Knife.
Phyla-Vell has Thanos and Maelstrom
Rocket Raccoon has Lord D'vyne and Blackjack O'Hare. Ironically the later would end up joining the team.
Matt Fraction's Hawkeye set up Madame Masque as Kate Bishop's arch-enemy, which continued afterwards. While it's for largely petty reasons (Kate tied her up and stole her identity for an issue), Masque has devoted an absurd amount of time to wrecking Kate's life ever since.
The Incredible Hulk has the Leader, the Abomination and Gen. Thunderbolt Ross. One could even make a case about Hulk being Banner's.
Doc Samson has Patchwork.
The original Human Torch, Jim Hammond, has the Mad Thinker. In the Golden Age, he had Adolf Hitler.
The Inhumans and their king, Black Bolt, have his insane brother, Maximus Boltagon the Mad, as their Arch-Enemy. Currently (July 2012), the two have buried the hatchet, with Maximus loyally, if eccentrically, serving Black Bolt. Afterwards, Vulcan and Lineage became the new arch-foes of the Inhumans.
Iron Fist has Steel Serpent, who coveted the Iron Fist power, and Master Khan, a sorcerer who has battled Iron Fist multiple times.
Iron Man's traditional Arch Enemy was The Mandarin, but he's faded a bit over time as the Yellow Peril aspect of the character is no longer kosher. Matt Fraction brought him back in big way during his run on Invincible Iron Man however, nicely cementing The Mandarin's status as the worst that Iron Man's rogues gallery has to offer.
Seeing as thirteen different people have taken up the mantle, the Crimson Dynamo certainly is one of his most recurring and dangerous enemies, and has the best shot, after The Mandarin, of claiming this title. As a Communist holdout, the Dynamo also makes a useful counterpoint to Stark's capitalist ideology.
During the eighties and nineties, and up until his apparent death in the early 2000s, evil industrialist Justin Hammer served as the archenemy of Tony Stark. He was the mover and shaker behind "Demon in a Bottle", "Armour Wars I", and several other major arcs, and made repeated attempts to take down Stark Industries and their founder, all in order to increase his own profits. Hammer was one of the few villains Stark always took seriously, their hatred was definitely mutual, and in the end, his legacy lives on to this day in the form of his equally mad daughter and granddaughter.
Jessica Jones has Purple Man, a mind controller that kidnapped her years ago.
Ka-Zar has his brother, the Plunderer.
Kid Colt has Iron Mask, a villain clad in bulletproof armour, who fought Colt more times than any other foe.
Luke Cage has Chemistro, who wants revenge on Cage for imprisoning his older brother, the original Chemistro.
In his early years, Moon Knight had Raoul Bushman, Marc Spector's commander in his mercenary days. However he later developed a more fitting and lasting archnemesis in the form of Black Spectre, his Evil Counterpart who's motivated entirely by a desire to be like Moon Knight. Even when the first Black Spectre died, a new one sprung up with a similar motivation to torment Moon Knight barely a year or two later in-universe.
Miles Morales inherited the Green Goblin from his predecessor, Peter Parker in the Ultimate Marvel continuity, but his biggest arch-enemy thus far is his uncle Aaron Davis, aka the Prowler of the Ultimate universe. And unluckily for Miles, Aaron followed him to the main Marvel universe.
Carol Danvers aka Captain Marvel hasn't had a consistent Rogues Gallery since her rebrand, but Mystique still stands as her arch nemesis as it's very personal between them. Ms. Marvel Vol. 2 #48-50 even refers to Mystique as Ms. Marvel's archenemy.
For the newest Ms. Marvel, Kamran and Becky St. Jude aka Lockdown. With Kamran, It's Personal as he kidnapped her brother and Kamala knew him when they were children. Lockdown is more of an Evil Counterpart as they share the same heroic aspirations but they're total opposites and mainly because Becky is a sociopath.
Though it was short lived due to him dying before anything more could come from it, Nova had a very personal hatred of Annihilus after the Annihilation Wave wiped out every single member of the Nova Corp besides him on the first day of the Annihilation event. Shortly after, Annihilus killed his friend and ally Quasar in front of him. Nova made it abundantly clear from the event to his death that his hatred of Annihilus was very personal. At one point he even went into an violent uncontrolled rage when he found a small surviving segment of the Annihilation Wave attacking a planet weeks after the war ended. He ended up killing all of them in blind rage.
Nova also had Ego the Living Planet, who once turned to Nova Corps against Rider and had him stripped of his powers. When Rider regained his powers, he had Ego lobotomized.
Sam Alexander and Warbringer. Warbringer is a Chitauri warlord who tried to destroy the Earth because Sam helped his gladiator slaves escaped him. After being severely injured in a battle with him, Warbringer said he had only survived to kill Sam.
The Prowler has Nightcreeper.
Puma has the Beyonder.
The Punisher has Jigsaw. In The Punisher's case, "Arch Enemy" just means "enemy who's still alive". In the MAX imprint one could make a case for Barracuda for similar reasons.
Also Mephisto, who hates Norrin for just being so danged good.
Silk has Black Cat. Silk has foiled Black Cat's schemes to unmask Spider-Man and infiltrated her organization as a mole for S.H.I.E.L.D., and Black Cat has defeated Silk on multiple occasions and hindered Silk's efforts to find her parents.
Spider-Man has had no less than three Arch Enemies: Green Goblin, Doctor Octopus, and Venom. The reason for this is that the Green Goblin, otherwise the uncontested contender, died in the 70s and spent a good 20-odd years dead before he came back to torment his foe, which is probably the record for dead A-list villains to beat. In the meantime, Doctor Octopus and Venom filled the roles in the seventies and eighties/nineties, respectively. This also means the latter two are arguably more famous, even though the Goblin is the greatest overall threat of the three. Another reason is that the Goblin, as Norman Osborn, suffered frequent bouts of amnesia in the run up to his death so he didn't even remember that he was Spidey's arch-enemy, which helped Doc Ock who was the next most formidable villain. Venom appeared in the 80s and made his chops by being in some ways a more personal (and visually stunning) enemy than either of the other two, while Ock was Demoted to Extra. So essentially, Spidey has three arch-enemies because they kept replacing each other. After his return from the dead in the late nineties, the Goblin was for a long time seen to be Spidey's one true Arch-foe, and even became a major player in the Marvel Universe at large. Under Dan Slott's pen, however, Doc Ock has been catching up, with schemes to bring about The End of the World as We Know It, a "Freaky Friday" Flip that screwed Peter's life over big time, and eventually forcing Spidey to give up his company, which Peter considered his life's work.
The Green Goblin. Unlike most superhero arch-villains, he actually is the most dangerous foe of his enemy, possessing far greater resources and deep personal information (he was the first to discover Spider-Man's secret identity) that the other two mostly all lack (though one could argue that, apart from Osborn killing Gwen Stacy, Venom was originally more personal with his invasions of Peter Parker's life). Since his return to Spider-Mans world, Osborn did everything he could to make Peter's life miserable, usually through really nasty Revenge by Proxy schemes, including burying Aunt May alive and stealing Peters child. Osborn is also firmly convinced he is the single Arch-Enemy to Spidey, and was pissed Dock Ock, Spidey's "number two" in his opinion, got to kill Spider-Man.
The Green Goblin of the Ultimate universe is the undisputed archenemy of Spider-Man. He not only created both Spider-Men, he was also the one who killed Peter Parker. This version of Norman is much more insane, having a Messiah complex. He believes God wants him to kill Peter and everyone he loves, and blames him for the death of his son and his own shortcomings. Norman embodies the exact opposite of everything Peter stands for. The worse thing is the OZ formula made him immortal and it's implied that the OZ-affected spider did the same for Peter, so they're stuck fighting each other for eternity.
Doctor Octopus: What Peter could end up becoming if he abused his intelligence and powers. (Peter was even a former student of his in the animated series). Also the first villain to really defeat Spider-Man, completely shattering his confidence for a while, and is certainly the longest lasting and most recurring. Although the Goblin initially overshadowed Ock after his return, Ock in recent years has performed several maneuvers,including outright stealing Peters life, putting him back in the race for the Arch-Enemy status.
One important thing to consider in this contest is that there are several crucial differences between how both Osborn/Goblin and Ock approach their relationships to Spider-Man. This distinction was thoroughly explored in the "Superior Spider-Man Team Up," where two villains temporarily join their forces to defeat their mutual foe.
Although initially Green Goblin wanted to kill Spider-Man to earn reputation in the criminal underworld, later their feud turned much more personal as Osborns goal shifted to punish Peter Parker (not Spider-Man) in the cruelest way possible. It is telling that destroying Peter became pretty much his singular focus in life and his favorite form of entertainment. While for Norman this hatred is mixed with at least some form of secret admiration of Peter, the latter understandably feels nothing but hatred for the former, and repeatedly crossed some of his usual lines to get revenge on Osborn. Notably, Peters jokes when fighting Green Goblin or Osborn, if they are present at all, are far colder and drier than with anyone else.
With Otto, on the other hand, it is a different story. Unlike Osborn, Octavius has his own code of honor and tries to avoid harming innocents in his feud even going as far as acting like a gentleman to Peters loved ones. Unlike Osborn, Otto prefers to keep his enmity with Peter strictly to "Doc Ock vs Spider-Man", a classic supervillain vs superhero rivalry, and generally just wants to defeat Spider-Man instead of ruining the person behind the mask. He and Peter actually have a lot of mutual respect for each other, despite all the bad blood between the two and voluntarily joined their forces more than once. Peter likes to joke around Otto, probably more than with anyone else.
As Stan Lee put it himself: "The Green Goblin is Peter Parker's greatest enemy, while Doctor Octopus is Spider-Man's greatest enemy."
Venom: An Evil Counterpart who mainly filled the role in the late eighties and nineties. Not only is he effectively an even stronger version of Spidey himself note In direct combat, he was often the most powerful of the three. , but Peter's Spider-Sense doesn't work on him, which means Eddie / Venom could be right behind him without Peter knowing, and Eddie played up this Paranoia Fuel for all it's worth while menacing Peter. Being bonded with the symbiote also gave Venom knowledge of Peter's secret identity, which Venom immediately used to scare Peter by harassing Mary Jane and Aunt May, making Venom far more invasive than the other two were at the time. As Venom became more of an Anti-Hero and later on a Legacy Character, however, he doesn't really fill the spot the main comics nowadays. He very much does in many adaptations, though. These adaptation make Eddie's grudge against Peter more personal and/or believable, as Venom's initial grudge against Spidey was admittedly a bit weak in hindsight. His overall goal, at least in adaptations, is a combination between Goblin and Doc Ock's - destroy Spider-Man, and ruin Peter Parker simultaneously, and in both Spider-Man: The Animated Series and The Spectacular Spider-Man, he even tried to unmask him in public. Peter finds Venom's almost encyclopedic knowledge of him genuinely terrifying, and during the climax of Venom's original story, Spidey's fight with him became less of just a hero fighting a villain into more of a man pulling off and coming up with every tactic he can in a desperate act to fight for survival - against a much darker, smarter and stronger mirror of himself. While Goblin and Ock are Peter and Spidey's greatest enemies respectively, Venom, at least pre-Anti-Hero, could be seen as the greatest foe - and fear - of both identities.
In addition to Spidey, Venom has Carnage, his symbiotic son bonded to a Serial Killer Cletus Kasady, as an arch-enemy, regularly setting aside his grudge with Spider-Man to take Carnage out due to him posing an extreme danger to civilian life.
Star-Lord has Thanos, who betrayed him and forced him to sacrifice himself to stop Thanos from destroying the universe. Although Star-Lord survived, his comrade, Nova, did not. There's also J'Son, his Archnemesis Dad who is also the leader of the Spartax empire.
Namor has Attuma. Attuma is constantly trying to usurp the throne of Atlantis from Namor.
Thor also has Loki's son, Jormungand. Thor and Jormungand tried to kill each other several times before Ragnarok in part to defy fate. Thor ended up killing the serpent several times, but it always returned for Ragnarok.
Angel has Apocalypse and Cameron Hodge. Hodge, on the other hand, was his former friend before he became an anti-mutant supremacist out of jealousy of Angel's powers. At one point, Hodge even had Angel's wings removed.
Banshee and his cousin, Black Tom Cassidy.
Beast and Dark Beast, his alternate universe counterpart who kidnapped Beast and killed his loved ones to cover it up.
Bishop has Trevor Fitzroy, a criminal he is pursuing across time.
Cyclops and his family have Mister Sinister, who is obsessed with gaining control of the Summers bloodline, and has repeatedly used cloning and various other gambits to get said control. Scott takes this very personally.
Cypher had Magus. Due to his connection with Warlock, Cypher has had multiple encounter with Magus, and Cypher once even turning Magus into an infant.
Elixir has Wither. Both were in a love triangle with Wallflower before she died, and have the opposite powers to one another. Elixer heals, Whither... whithers things.
Emma Frost has her psychotic sister, Adrienne Frost. She also has longstanding enmities with her former Hellfire Club colleagues, including Sebastien Shaw and Selene.
Fantomex has Sublime, Ultimaton, and Huntsman.
Forge had the Adversary, for whom he was trained by shamans to defeat.
For Gambit its usually Mr Sinister or the External Candra.
Hepzibah has Vulcan and D'Ken.
Havok used to have the Living Monolith, who fed off Havok's power. More importantly, Havok has his younger brother Vulcan.
Hope Summers and Bastion. Bastion resurrected the X-Men's most dangerous human villains and sent them on a campaign to kill Hope, the Mutant Messiah. Bastion was eventually destroyed by Hope herself.
Jean Grey has Mastermind and Madelyne Pryor. Mastermind once brainwashed Jean Grey (actually a duplicate, although the real Jean later absorbed memories of the incident) into becoming his pawn, and she left him catatonic after she found out the truth. Madelyne learned that she was a clone of Jean Grey and was abandoned by her husband, Scott Summers (who fell in love with her because of her obvious similarity to Jean, though neither knew she was a clone at the time, assuming it to just be mere coincidence that they looked exactly alike), when he reunited with Jean, after Jean returned from the dead. As a result, a vengeful Madelyne went insane and became consumed by hatred for Jean for ruining her marriage.
Jubilee and Hunter Brawn, the man who killed her parents.
Karma had the Shadow King and now her older sister.
Kitty Pryde and Ogun, who tried to brainwash her into killing Wolverine, and continues to haunt her a a ghost even after his death.
Lilandra had her sibling, Deathbird and D'Ken, both of whom are out to usurp her throne.
Rogue's arch-nemesis is her adopted mother Mystique, due to Rogue feeling like she's being used.
Longshot has Mojo and Spiral.
Magik and Belasco. Belasco turned Magik into what she is, and she has never stopped blaming him for this, and usurped him as ruler of Limbo. Eventually, Belasco's daughter took over this role for Magik.
Magma and Selene. Selene usurped control of Nova Roma from Magma's father, forced Magma into hiding for years, psychically tortured her on multiple occasions, and was revealed to be Magma's ancestor. Magma fears and hates Selene more than any other person.
Northstar has Gorgon. Gorgon is responsible for Northstar's death and the hands of a brainwashed Wolverine, and his own subsequent resurrection as an agent of HYDRA. Northstar also has Pestilence and Deadly Ernest.
The Phoenix Force has the Goblin Force and Le Bete Noir.
Pixie has her sisters, Lady Mastermind and Martinique Jason.
Polaris has Malice, who possessed her body.
Psylocke has the Shadow King and Matsu'o Tsurayaba. The Shadow King temporarily destroyed her psychic form, nearly killing her, temporarily forced Psylocke to sacrifice her telepathic powers to keep him imprisoned, and once tried to make her his queen.
Rachel Summers has the Beyonder, Ahab and Selene. Rachel made multiple attempts to kill the Beyonder because he was a threat to the multiverse, but the Beyonder made things personal when he gave Rachel a portion of his power, and proceeded to threaten the lives or her friends just to test her. Eventually, Rachel delved into He Who Fights Monsters territory and nearly destroyed the universe to free it from the Beyonder's influence. Ahab, on the other hand, was the man who turned her into a Hound, and after she escaped he fixated on getting her back. She's also gone up against Selene a few times and is a thematic Foil (Rachel's a young woman from the future and Selene's an ancient evil). Then there are the Shiar Death Commandoes. Nuff said.
Sage has Elias Bogan.
Shatterstar has Mojo and Spiral.
Storm has the Shadow King. He employed her as a thief when she was a child, but was never able to completely bend her to his will. Her strength of character makes her his favorite target.
Strong Guy had Damian Tryp. Tryp once brainwashed Strong Guy into becoming a mole in X-Factor and murdering a man he was assigned to protect.
X-23 and Kimura: Both were victims of physical and emotional abuse and lost the person who could have helped them recover, but while X chose to heal, Kimura uses it as an excuse to hurt others. Kimura is also physically invulnerable, so Laura is unable to defeat her in a direct fight.
X-Man and Apocalypse by design. Thereafter, a case could be made for either Sugar Man or Holocaust.
Generation X (specifically M, although he targeted the rest of the team as well) had Emplate.
The New Mutants had Emma Frost, Sebastian Shaw, Selene, and Donald Pierce.
The New X-Men had William Stryker and Sean Garrison.
X-Factor had Apocalpyse and Cameron Hodge in its first incarnation, Mr. Sinister and the Nasty Boys for the X-Factor Government Team, and Damian Tryp For X-Factor Investigations.
X-Force had Stryfe and the Mutant Liberation Front.
Sabretooth is Logan's primary one, as he represents Wolverine without any inhibitions, giving into his feral nature. Beyond that, Creed makes it a tradition to find Wolverine on his birthday and kill a woman he is fond of. It was also later retconned that Logan inadvertently got Victor's girlfriend killed by encouraging her to fight an anti-mutant organisation, and Victor blames Logan. There's also a helping of Evil Former Friend in there, as the two were friends when they had their memories wiped, something Logan recalls with a degree of fondness. All this has created a blood feud that has lasted decades because of the two being borderline immortal.
An attempt was made to kill off Sabretooth and make new villain Romulus Wolverine's new arch-enemy, but it failed spectacularly. Romus was revealed to have been responsible for almost everything bad to ever happen in Wolverine's past, including the Weapon X program. He also corrupted Daken by having his mother killed and raising the boy. Basically he was forced into the position of archenemy by killing off Sabretooth and making him responsible for pretty much everything bad in Logan's life. Unsurprisingly, it didn't take, and the character has been ignored since.
Lady Deathstrike has also had a long career as Wolverine's secondary nemesis. Lady Deathstrike despises Wolverine both for "stealing" her father's adamantium, and for defeating her on multiple occasions. Lady Deathstrike even went so far as to upgrade her body with adamantium so she would become a match for Wolverine. The vendetta is personal on Wolverine's side too, because she crippled Wolverine's friend, Yukio.
Agent 327: Hendrik I Jzerbroot's most dangerous opponent is Boris Kloris.
Asterix: Julius Caesar would be this, even though there's a mutual respect between the Gauls and Caesar. Caesar is often seen as a Voice of Reason and above the pettiness of many of the prefects.
Astro City: Samaritan has Infidel, who have both traveled through time to change history and thwart each others' schemes. They give up the feud once they realize that neither of them will ever be able to destroy the other, even if the Universe itself is destroyed.
Atomic Robo has the Nazi Baron Heinrich von Helsingard. Dr. Dinosaur may also qualify for Robo in modern times.
Thomas Edison for Nikola Tesla and, by extension, Robo.
Majestic 13 for Tesladyne...and again, by extension, Robo, but also former agent and full-time Memetic Badass Jenkins this time.
In their fictional universe the characters from the two British ComicsThe Beano and The Dandy are arch enemies with frequent jokes but at the other's expense and infrequent raids between the comics. This arch enemy rivalry has died down quite alot since The Dandy's revamp. Also characters from within the two comics have their own arch enemies as well. Dennis the Menace (UK) has Walter the Softy, Roger the Dodger has Cruncher Kerr The Bash Street Kids had the Blob Street Kids, the Three Bears had Hank and Grizzly Gus (another more evil looking bear who hasnt been in the strip for years) and Desperate Dan had either Cactusman or Dangerous Dan McGroo.
This arch-enemy comic rivalry was taken Up to Eleven in the Fleetway comic Whizzer and Chips which was one comic which was made up of two comics and these two comics and their characters were archenemies with even more frequent 'raids' in the two comics than with the Beano and Dandy.
The Crow has Top Dollar, the man who arranged the murder of Eric Draven and his girlfriend.
De Kiekeboes: Balthazar is the most recurring antagonist in the series, though generally considered to be a Harmless Villain. Far more dangerous are Timothea Triangl- a James Bond type villain who underwent a sex change- and Dédé La Canaille, a criminal who wants to murder Kiekeboe for putting him into jail.
Scrooge McDuck has several different enemies competing for the title. He often combats the Beagle Boys, though Blackheart Beagle, the oldest member and their founder, is the only one whom Scrooge has a personal vendetta with. His business rivals Flintheart Glomgold and John Rockerduck sometimes function as his own personal arch enemy(ies) too, given their status as Evil Counterparts of Scrooge. However, his most dangerous opponent is the witch Magica Despell, who threatens to steal his lucky dime and melt it in the Vesuvius volcano. One could also add Arpin Lusene, a Gentleman Thief who holds the distinction of being Scrooge's only Worthy Opponent.
Donald Duck considers both Gladstone Gander and Neighbour Jones his personal arch enemies, though these are of the sitcom variety. He does have an extensive Rogues Gallery in Paperinik New Adventures, but no single bad guy has managed to stand out as his definitive arch-enemy.
Mickey Mouse as seen in more recent Mickey Mouse Comic Universe stories has his own kind of dynamic with his two arch enemies Pete and the Phantom Blot. Mickey is typically more or less an Amateur Sleuth, naturally opposed to both of them as professional criminals. Pete is generally shown as a more crude but very experienced and enterprising criminal, whereas the Blot is a shadowy criminal mastermind. Pete is not completely evil and has been shown with a kind of affection towards Mickey as an opponent and is more prone to end up in an Enemy Mine situation with him, whereas the Blot is closer to being simply sociopathic. The two can even get contrasted in the same story, with Pete more human and the Blot more effortlessly smooth and evil. It's still Depending on the Writer.
Jommeke: Jommeke and his friends are often confronted by Anatool, the servant nobody can trust. However, he is somewhat of a Harmless Villain, seeing that Jommeke and his friends can easily thwart his evil schemes. De Koningin van Onderland ("The Queen of Onderland") on the other hand doesn't appear that much in Jommeke's stories, but when she does she is generally considered to be his most frightening and dangerous opponent.
Lucky Luke: Lucky Luke most often faces off against the Daltons. About half of the albums are about the Daltons and the rest about everyone else. Billy the Kid is the second most recurring villain and he still doesn't come close to their approaching Villain Protagonist status.
The Mad Hatter: The Gargoyle, a criminal resurrected as a Beast Man, was clearly supposed to be this for the Mad Hatter, due to the implication that he'll return, but he debuted in the final issue of the comic, so he didn't get the chance to full come into his evil.
One volume of Powers deconstructs the usual comic treatment of archenemies. It shows what were essentially the world's first superhero and supervillain. The two are immortal and have existed since humanity was still diverging from the ape, and have had a grudge just as long. When they meet for the last time in the present day, the hero, (who has a case of The Fog of Ages) demands to know why he and the villain have been fighting so long. The villain, whose memory is not impaired like the hero's, admits that he can no longer even remember what originally sparked their feud.
The Phantom: The Phantom is traditionally opposed by the current leader of the Singh Brotherhood; the 21st Phantom first battles Dogai Singh, and later, his daughter Sandal Singh. Other notable enemies include the mercenary Gold Hand and the evil President Lubanga.
Planetary and the Four, especially their respective leaders, Elijah Snow and Randall Dowling.
Jesse Custer in Preacher has Herr Starr, the Saint of Killers, and God. Yes, theGod.
Quick and Flupke: Quick and Flupke are often confronted by Agent 15. Seeing that the two boys are brats your mileage may vary whether Agent 15 is actually the hero of the series or not.
In "The Fires of Pharos", Commander Kaaj swears a blood debt against Captain Pike for destroying the Pharos siteworld. In "The Flat, Gold Forever", he lures Captain Pike away from the Enterprise with a Forged Message and attempts to kill him so that honor can be satisfied. When he later sees Pike on the Temazi homeworld in "Thanatos", he cannot contain himself. He attacks Pike in the Temazi shrine, thereby blowing both of their covers.
In the Alternate Timeline story arc "Futures", General Chang has seemingly taken Kaaj's place as Captain Pike's Klingon adversary. In "Now and Then, Part Four", he even compares his conflicts with Chang to "the bad old days with Kaaj."
Strontium Dog: Johnny Alpha has his father, Nelson Bunker Kreelman, a racist politician who abused and ultimately locked his own son up for his mutation, and leads a Nazi-like anti-mutant movement.
The Shredder to the Teenage Mutant Ninja Turtles and their mentor Master Splinter. Shredder goes down pretty early in the original comics. However, the first issue clearly shows the backstory Splinter and Shredder have, that Splinter and the Turtles owe their origins to Shredder, and that Splinter trained the Turtles for the sole purpose of killing Shredder to avenge Hamato Yoshi. Regardless of how long Shredder was around for, he's still their archnemesis.
The archenemy dynamic is played interestingly in the story. After Shredder was killed, the Turtles never really had another central enemy. A few issues show that the Turtles aren't really sure what to do with themselves with Shredder gone. In fact, in the City At War arc that capped off the original series, Leonardo argues that killing Shredder was more Splinter's goal than theirs.
Tomboy (Sterling): Despite being a One-Shot Character, it's heavily implied the Lard Vinsion, crime boss and Big Bad of Captain Flash #3, has tangled with Tomboy many times before, an honour no other villain receives.
Tom Poes: Bul Super and Hiep Hieper. Even though Joachim Sickbock and Hocus P. Pas are far more dangerous.
The Wasp (Lev Gleason): The Professor was clearly supposed to be theist the Wasp, what with being a Diabolical Mastermind who wants revenge for an offscreen prior defeat, and a blatant Sequel Hook indicating that he will return next issue, but the comic got cancelled after his debut.
The WildCATS have Helspont, leader of the Cabal and one of the most powerful Daemonites in existence.