Many MMORPG games feature "emotes" — brief animations, text, and/or sounds that let your character perform an action irrelevant to the rest of the game, such as making your character laugh, dance, or cry. It's not uncommon for such games to also include options to make your character burp and/or fart.
Animal Crossing: New Horizons lets you perform feats of strength — in particular, digging up trees and breaking rocks — by eating fruit, and each feat uses up one fruit. If you sit on a toilet with fruit power that has not been used up, a cutscene ensues in which the fruit power counter decreases to zero, implying that your character pooped it out.
"And that takes care of that!"
Banjo-Kazooie contains a lot of toilet humor. One level involves going into a sewer and has burps and farts as a part of the background music. Captain Blubber's speech sound was him burping numerous times and one mini game involves getting into an eating contest with a crocodile that burps every time it eats something. Judging by the sound effects, Kazooie also seems to fart out her eggs rather than laying them. Also, one of the random facts about Gruntilda the player can learn is that her party trick is "blowing up balloons with her butt".
Beyond Good & Evil makes it pretty clear that Pey'j's jet boots are fart-powered, without actually saying so. Specifically, they're "fueled by a pocket of natural methane" [cue closeup on his rear end] "—just flex your abdominal muscles!"
If you keep watching Kapura for a while in BIONICLE's Mata Nui Online Game, you can see him performing fart-fueled jumps. He also releases one in a cutscene, which leaves his butt smoking. It was never explained how a cyborg who allegedly never eats does this, and it never comes up after the game, so it's probably Early-Installment Weirdness.
Borderlands 2 starts with "Dook Hut, No Fapping" signs on the porta-potty weapon containers.
Borderlands 3 tells users of the porta potty to clean up their dooky. Also, some screens in the spaceship keep track of various gasses (O2, N, CO2), with one screen having CH4 zoom all the way to the right to show "Caution: Excessive farts detected". In a darker version, there's also the Porta-Prison mission, in which a bandit is locked in a porta-potty by a bureaucratic A.I. issuing fines.
The Breath of Fire series does this not once but twice, and as actual parts of the plot at that:
In Breath of Fire IV, there is a segment where one must essentially meet up with fairies...and obtain Fairy Drops. As an intrinsic magical ingredient to reforge a broken sword. And the Drunken Master of the party even comments in horror that it's fairy shit.
One of the unlockable cats in Catlateral Damage is called "Fart Cat", and unlike the others, this cat makes fart sounds instead of meowing when the "meow" button is pressed.
Sinder, one of the characters in Cel Damage, constantly mentions urine. Some of his lines include: "Did you wet yourself, or did I?", "Ah, I go pee!", and "I gotta go to the bathroom." Heck, even the intro shows him leaving a yellow puddle on a rug, while the announcer mentions that he's not house-trained.
Nekomaru Nidai from Danganronpa 2: Goodbye Despair fits this trope very much to the point that NintendoCapriSun would be proud of him. He often declares that some great life rules to follow are to "EAT WELL, AND SHIT WELL!" and during the party in the first chapter, Nidai ended up desperately having to go to the bathroom, but Pekoyama was occupying it, which by itself is also funny, considering the character. Also, when Nidai and Hinata briefly team up in Chapter 4, Mecha-Nidai always pauses in front of bathrooms to stare unhappily and also mentions that the inability to poop is one of the few things he regrets about his robotic condition.
Deathmaze 5000 was a game for the TRS-80 in which one used the keyboard to navigate a block graphics maze. To save time and keystrokes getting to the end of a long straight hallway, you could type "fart", which would blow you down the hall until you slammed into the wall at the end.
‘’Destroy All Humans’’
In the original games when you use the Anal probe on people it would cause them to poop and hold their buts, dah 2 the gun made fart sounds
Dog's Life allows the player to enter certain button combinations (all of which are in the manual) to make the playable canine fart, pee and poop. Taken to the extreme in that you can also make the dog pick up his own fecal matter in his mouth and throw it at people. Because of this, the game ended up with a Teen rating, even though the rest of the game is very obviously intended for younger audiences.
Donkey Kong 64: One level features a giant piano that, when played, has kremlings pop out and belch. Naturally, a memory-based matching game is played using it. Also, Chunky Kong's charge-up attack features him belching loudly.
As the name suggests, Don't Shit Your Pants is made of toilet humor, since the goal of the game is to guide the protagonist to the restroom and get him to have a successful bowel movement. Its sequel, Don't Wet Your Pants, is like the same but with peeing.
In Fable II, you can interact with NPCs using various expressions, including burping and farting. Done right, both seem quite popular amongst Albion's inhabitants, save for the most serious citizens. But fail these and you'll have to face the rather unpleasant and disgusting consequences.
In Fable III, not only can you only do both in NPCs' faces, but the smell of your character's farts is also so potent that they make the NPC pass out during the animation.
During a cross-dress up quest in Midgar, there's a woman in a bar's toilet that Cloud can open. You have to give the woman one of the medicines to help a man who is desperate to run in and relieve himself. Also in Midgar, when the party infiltrates the Shinra building, they observe a secret meeting by stepping into a bathroom stall and climbing into a secret passageway located by accessing a ceiling hatch above a toilet and you have the option to flush the toilet.
There are several other toilet scenes later on in the towns of Rocket Town, with a guy pooping in a toilet and a guy needing to use the bathroom. When visiting Icicle Inn, a woman punches Cloud for peeking in on her, but only if you manage to dodge Elena's punch before going down to the basement of the inn.
From Dissidia Duodecim, after Kefka eavesdrops on Cloud and Kuja's heart to heart talk:
Kefka Palazzo: What's this? The brooder and the narcissist having a heart-to-heart? Oh, this is rich — so rich it gives me gas! Gives me gas, I say! Ho, ho! [farting sound] And I give it back.
Horse Manure, which is a pile of horse poop, is a pretty uncommon Joke Item that you can give to your allies, but is almost completely useless beyond triggering unique dialogue from the receiver, usually reacting in disgust. Its item description even advises against gifting it to your allies.
"Ordinary horse manure. That’s it. You could technically give it to someone, but why would you?"
One of the named areas is Flush Factory, a factory dedicated exclusively to producing toilets.
In Free Realms, there was a period where you could use emotes to burp and fart. A later patch removed the fart emote, but it is still possible to make your character fart by doing a quest where the reward is a flatulence-causing potion.
In Gobtron, the player character's attacks are all gross-out based. Its starting attack is a Slingsnot. Later on, it gets snot projectiles, spit bubble shields, a Smart Bomb burp, and an even stronger fart. And then there's the level select/upgrade screen, an intestine covered in cysts that expand as you "upgrade" your weapons, The "start level" shows an arrow pointing to the end of the intestinal tract.
Grand Theft Auto: San Andreas: Remember the poor foreman who went to take a leak in a mobile loo and ended up cemented into a hole? Judging by his comments, he probably would have preferred a clean headshot...
Hell Pie has a lot of fecalphilia in it. There are demons who buy feces at the supermarket, and a species of feces-eating humanoid blob people called munchers.
Tangent's presentation for the science fair at the first Vertumnalia Festival involves using the hydroconversion machine for other benefits besides making urine drinkable. Despite her saying the word "pee" many times, the protagonist finds Tang's presentation boring.
During the 4th Vertumnalia Festival, Geranium serves pixie beans, the first domesticated Vertumnan crop, which glows in the dark. His wife, Flulu, jokes that the community will have to thank him for the "light show in [their] toilets tonight."
One time during work at the Supply Depot, Tangent feels embarrassed when she asks the protagonist to get her "fart pills" for her upset stomach. Marz then teases her that she got the bad case of "Bluegut", or when she farts blue dust and stains her pants with it, and she makes her check her own butt, to her dismay.
Metal Gear Solid made up for not being able to stand under it with being able to take piss from wolves! This is not only comedic relief but also actually serves as a gameplay mechanic: Snake is immune to wolf attack after having wolf urinated on him (the wolves will think he's one of them).
In a Codec converstation in Metal Gear Rising: Revengeance, Doktor tells Raiden that in order to use a terminal, he first needs to "take a DOOMP". This catches Raiden off guard, until Doktor clarifies that he meant a digital-optical output mounted proxy.note In the Japanese version of the game, Doktor says they need a springboard. Raiden assures him that he can jump high, but Doktor tells him that he meant a hacking springboard.
Playing up the toilet humor to ridiculous levels was the point of EarthBound (1994)'s infamous advertising campaign; remember, this is the campaign which proclaimed its subject to be the "first RPG with BO". The game (and series) itself does touch briefly on it on occasion, but definitely nowhere near to the extent that the campaign implied.
Mother 3's final chapter includes a "special all-you-can-pee toilet dungeon".
Moshi Monsters: While it isn't brimming with toilet humour, there are a few toilet jokes in it.
Squiff the Glump (Glumps are evil blob-like creatures) is said to fart a lot as his secret weapon.
Wobble-Ade, a soda that sometimes acts as a Fantastic Drug, is said to make you burp, which resulted in a burping contest in the mission "The Curse of the Paw Wavin' Kitten". Bongo Colada also makes you burp, which is sometimes brought up as a joke.
In one mission with a "Fantastic Voyage" Plot, you have to avoid "snot goblins" while piloting the ship through the nose.
Two ingredients for a shrinking potion are bat droppings and troll snot.
One of the snowballs is yellow and is described as disgusting.
Snot is a Running Gag, with it even being something you can paint your pets with. Dung is another running gag, with piles of it popping up randomly and there even being a Dung Faerie.
Nintendo Land seems like the kind of game where this wouldn't be present. However, in the game's Pikmin themed minigame, if you're eaten by one of the creatures, you'll be ejected out as a clay turd.
Throughout the No More Heroes series, toilets have served as save points, with Travis dropping his drawers and copping a squat when saving progress and toilet paper "tastefully" blocking the view of Travis's genitals.
Ōkami allows you to urinate and defecate on enemies. (Not as bad as it sounds. The protagonist, while a goddess, is still a dog.)
Orc Attack: Flatulent Rebellion is built around this, as the game centers on using burp and fart attacks as a means to fight off waves of enemies. Even three of the four playable characters' names involve "poop" or a synonym for it.
Stage 5 of PaRappa the Rapper has PaRappa desparately needing to use the bathroom. Unfortunately, so do his previous mentors, who are already lined up, so PaRappa engages each one of them in rapping duels in order to cut in line, with all of the mentors' lines being tailored to suit the occasion of having to go to the bathroom so badly. If he succeeds, he gets to relieve himself on the toilet. If he fails, a cutscene of a rocket taking off is shown, implying that he went in his pants.
The German mini game Pipiprinz is based on a Real Life event when Ernst August von Hannover got drunk at the EXPO 2000, urinated in public, was photographed by a paparazzi and beat him up with his umbrella. The game is about drinking beer, urinating when "full", and beating up photographers.
The series has a Shop Fodder item known as a Nugget in English and a Gold Ball (きんのたま) in Japanese. Its Japanese name happens to be one character away from a certain part of the male anatomy. Yes, jokes are made. You're selling your family jewels.
Stunfisk's cry sounds like flatulence. Stunky and Skuntank's do as well, which is fitting because they're Smelly Skunk Pokémon who spray noxious fluid and whose faces are shaped like buttocks.
Most people are inherently suspicious of the Diamond and Pearl starter Chimchar, being a chimp with flames rising from his backside, but if they aren't sure yet, the Pokedex data does the rest, "Its fiery rear-end is fueled by gas produced in its belly." Zing!
Pokémon Black and White's Pokedex entry for Darumaka states that their droppings are hot, and people put them in their clothes to keep themselves warm.
Redneck Rampage cruises on this with the Gut meter. Having it high will get Leonard farting increasingly often, and so hard he's pushed forward. Crouching on top of a toilet has... audibly unpleasant results, and fully empties the Gut meter.
This is common in games of the Shrek franchise, given the nature of the movies they're based on.
In The Sims, giving a Sim a "slob" trait causes him or her to burp and fart randomly without inhibition. There's also a social interaction in which one Sim invites the other to pull their finger, followed by the expected results.
Messy Sims in The Sims 2 will burp and fart during/after meals. Also, the Cow mascot in University will burp in Sims faces, and some will like it and burp back!
The yet-unreleased Adventure GameSkaturd revolves around this. The aim of the game is to "spread fecal matter throughout the surrounding suburbs".
In Paper Mario: The Thousand-Year Door, meeting Punio with Koops active makes Koops remark at some point that X-Nauts "sound like tissues... to the extreme". Get it? Additionally, you do use toilets once to get from one room to another, and your partners have various things to say about the trip.
In Super Paper Mario, O'Chunks farts to fly away after being defeated in battle. There's also a Potty Emergency where Squirps needs to go to the bathroom but can't get in until you give its current occupant a piece of paper. This later results in Tippi calling him an incontinent little imp.
Marshall Law's ending in Tekken 6 has him make off with the prize money he earned together with Paul and Steve by putting laxatives in their pizza and escaping while they're... out.
Kuma, and by extension Panda, ever after Tekken 7 (at least) has had a move where Kuma will fart. Also, in Street Fighter X Tekken, Kuma's fart is the strongest move in the entire game (it does 137% damage but is hard as hell to hit).
The PC Engine game Toilet Kids is like Xevious if it were full of toilet humor. Enemies range from turtles with poop shells to toilets that shoot dungballs at you. Good thing it was never exported. Ditto for Kato & Ken, not counting its Bowdlerised localization JJ & Jeff.
Pretty much the entire point of the indie Xbox 360 arcade game Try Not to Fart, in which the goal is to hold it all in near your date.
In the game files for World of Warcraft, you can find a handful of outtakes that weren't used in the game. One of which was a /joke command that would make a human female character say "I like to fart in the tub." There also eems to be at least one quest per expansion that deals with...leavings. Probably the most infamous was the Alliance questline in Grizzly Hills involving Amberseeds (starting here).
In Yu-Gi-Oh! Monster Capsule GB, while in Hell's dungeon, Yugi can find a bathroom with urinals but no toilets. He can also find someone attempting to use said bathroom.