Per spoiler policy, all trope names and character identities are unmarked. As all of the spoilers in the game are tied to major revelations and other twists, especially the identities of the Parasites, beware of unmarked spoilers below.
Susan AshworthThe protagonist of the game and the titular "Cat Lady". A bitter, depressed woman who attempts suicide, only to be brought back to life and told to murder five "Parasites".
- Anti-Hero: She's really not a bad person, but she's bitter and antisocial. She isn't even actually trying to tangle with the Parasites, but they just won't leave her alone.
- Beware the Quiet Ones: Can be very soft spoken and quiet at times. That being said, do NOT get on her bad side. The parasites, as well as her Jerkass neighbor Brian learned the hard way.
- Big Damn Heroes: To the poor girl held captive by the First Parasite. Unless of course you decide to escape the complex without killing Doctor X, leaving him able to continue his work and kill the woman.
- Broken Bird
- Character Development: Over the course of the game, she slowly starts overcoming her depression, opening up to Mitzi, and taking control of her life. In the end, she still has a long way to go (and she will probably never beat her depression), but she's much better off.
- Crazy Cat Lady: Subverted. People only see her as this, whereas in reality Susan is just an ordinary woman who happens to invite cats to her home whenever she feels lonely, and she gives them the choice of staying inside or leaving rather than force them.
- Kind Hearted Cat Lover: Not at first. It's only until she learns to overcome her depression over time.
- Cynicism Catalyst: The reason why she is so bitter and depressed? She had a daughter at one time, when she was young, who tragically died from a rare pollen allergy when the pollen from Susan's flowers swarmed her room and caused her to suffocate. Susan and her husband Eric were having a huge fallout outside their daughter's room, and they failed to notice that their child was dying. Soon after, her husband left and killed himself.
- Determinator: Culminates near the ending, where she can refuse the Queen of Maggots help and resurrect without exchanging a life under her own power. The only explanation is she was just too stubborn to die.
- Doomed by Canon: She makes an appearance in the Downfall (2009) remake, the ending of which is chronologically set after The Cat Lady. In the end, she is either brutally murdered by Joe Davis after trying to save Ivy, axed in the back by Ivy, or revealed to descend into the Eye Of Adam's madness and start motivating other people to kill themselves. However, in the case of the "killed by Ivy" ending, a newspaper clipping reveals that she somehow survived the attack.
- Driven to Suicide: She overdoses on sleeping pills as soon as the story begins. She succeeds in taking her own life... for a short while.
- Happily Failed Suicide: Ultimately so, but it takes a long time before things start looking even remotely happy for her.
- Hidden Depths: She used to be nurse, and appears to have an interest in art and music, and is quite talented with playing the piano.
- Informed Attractiveness: Telling Doctor X that she wishes she was more attractive results in him telling her she's a beautiful woman, even listing her best features which aren't easy to discern on the sprite. (See also: So Beautiful It's a Curse below).
- Jerk with a Heart of Gold: Even right at the beginning of the game where Susan is at her lowest, she's not entirely standoffish around others. She bonds with a young nurse named Liz and becomes grief-stricken upon witnessing her suicide. This trait becomes more and more prominent as she continues to bond with her newest friend Mitzi, who helps Susan to learn how to trust other people again.
- Meaningful Name: Susan, which ultimately comes from the Hebrew word for "lily" or "rose". Also, Susan's daughter, Zoe, whose name means "life" in Greek.
- Ashworth is also the name of one of England's three high security psychiatric hospitals.
- Messianic Archetype
- Not Quite Dead:
- Par the course when you're immortal. Even if she is killed, she returns to life shortly afterwards.
- In the Downfall (2009) remake, Susan is axed in the back by Ivy in the Golden Ending and left to bleed to death on the ground. However, the ending newspaper clipping makes it clear that she survived the events. Whether it was because she still has her immortality abilities or because the game was mostly seen through Joe's eyes is left unclear.
- Resurrective Immortality: Thanks to the Queen of Maggots, whenever she dies, she comes back shortly after. She learns to use this to her advantage at several points. After rejecting the Queen, she loses this ability — though the Downfall remake puts this in question.
- Roaring Rampage of Revenge: Susan getting killed by the First Parasite, Doctor Xavier Zelmann, enrages her. The utter betrayal shown after she opened herself up and discussed her vulnerabilities to the senior psychiatrist led her to seek the parasite's death more earnestly than any other parasite. She makes it clear that while it's Nothing Personal to the parasite, it's very much personal to her.Susan: You treacherous dirty bastard!!! I opened my heart to you... and you stabbed me to death in cold blood!!! You'll pay for this, I swear you will!
- Screw This, I'm Outta Here!: An option you're given in Chapter 2 if you answered all of Liz's questions correctly. When you find her corpse, you can find the key to Doctor X's facility in her pocket, allowing you to escape forever - and allowing Doctor X to continue his work and resulting in the death of his current victim.
- Serial-Killer Killer: What she unwittingly becomes after the Queen of Maggots brings her back.
- So Beautiful It's a Curse: She's not exactly what you'd call beautiful, but apparently she's attractive enough to bring unwanted interest from people like the first and the second Parasites and her adulterous date from the flashback. In all those cases, let's just say, it doesn't end well for her.
- She Cleans Up Nicely: In the beginning, Susan appears to be very dishevelled and elderly, which is justified since she cares little about her looks and had just tried to commit suicide recently. But as she is able to change in a new set of clothes after her ordeals, she appears younger and more reasonably attractive.
- Sour Outside, Sad Inside: Susan's not exactly the nicest person inside her apartment building, and she's very prone to using bitter comments or sarcasm against others. In reality, she's suffering from depression over her grief of losing her daughter and husband, and having been let down by others once too many times, she adamantly refuses to open up to others for fear of trechery. It's only when Mitzi introduces herself as her lodger is when Susan starts to overcome this flaw.
- Took a Level in Badass:
- After encountering and getting killed by the First Parasite, she went from being in despair and lacking motivation to being absolutely determined and inspired to take revenge in retaliation for what was done to her and the countless victims and madness left in the wake.
- At the end of Chapter 4, she poisons the Second Parasite with Deadly Gas, then dons his gas mask, picks up his shotgun, strides back through the mansion, and blows his wife (the Third Parasite) away.
- What Beautiful Eyes!: Her green eyes are the only thing she likes about herself. Unfortunately, she's not the only one.
Mitzi HuntA young woman who Susan meets in Chapter 4. She becomes Susan's lodger and her only true friend.
- Bad "Bad Acting": When she tries to pull off being a babysitter while looking for The Eye Of Adam.
- Beware the Nice Ones: While she's one of the most compassionate people in the story, she's not afraid to speak her mind and shows no tolerance towards bullies. Throughout the story, Mitzi spends the remaining time she has left to live to hunt down The Eye of Adam, the man responsible for goading her boyfriend Jack to commit suicide over the news of her terminal illness. Upon finally confronting him in his apartment at the end of the story, Mitzi pulls out a gun she smuggled and threatens to shoot him dead, even if the shot would cause the apartment to explode due to the oxygen tanks leaking.
- Broken Bird: Like Susan, Mitzi has gone through some terrible ordeals in her life. Unlike Susan though, Mitzi hides her inner sadness with her optimism and compassion for others.
- Bully Hunter: She despises bullies, especially online trolls. This is why she is hunting The Eye of Adam, who brainwashes people and coerces them into killing themselves. Her boyfriend was one of his victims after he took the news of her cancer badly, fell into depression, and stumbled upon his website.
- Character Death: Can die in several ways. She either suffocates in a gas attack caused by The Eye of Adam if Susan puts on the only gas mask, dies in an explosion caused by an oxygen tank leakage if she shoots The Eye of Adam, or succumbs to cancer if the player fails to meet the requirements to achieve the Golden Ending. Keeping her alive in the end is notoriously hard to achieve. However, Word of God is that succumbing to cancer was meant to be her canon fate.
- Her canon fate is actually muddied by the Downfall remake, which sees her pop up with Susan at the end no matter what the outcome is. The way the story is set makes it clear that this takes place some time after the Eye Of Adam's death, but she looks no worse for wear and is still in high spirits.
- Childhood Friend Romance: She only ever had eyes for Jack, whom she grew up with. The feeling was mutual.
- Conveniently an Orphan: Her mother died long before the story takes place.
- Dark and Troubled Past: Mitzi's mother passed away early in her life, where she was then taken into an orphanage, as her family had wanted nothing to do with her. Since then, it's implied that she grew up as a small-time criminal as she had learned to pick locks, until she met Jack who gave her the "perfect love" she desperately needed. After settling down with Jack, Mitzi would then be diagnosed with a brain tumour, sending Jack into a depressive downward spiral that lead to his suicide. Mitzi would then spend the rest of her time left hunting down The Eye of Adam, the man who pushed her boyfriend to suicide, and kill him.
- Deuteragonist: Mitzi is essentially the second most important character in the story, and is also the most involved in the final chapter of the story where her and Susan confronts fifth and final parasite, The Eye of Adam.
- Expy: Her look is said to be inspired by a girl from Porcupine Tree's music video for ''Way Out Of Here''.
- Ill Girl: She reveals early on that she is dying of a brain tumour. If she doesn't die in the encounter with the Eye of Adam, she either succumbs to this in the normal ending or inexplicably makes a recovery in the Golden Ending.
- The Lost Lenore: Her boyfriend, Jack, was Driven to Suicide by the Eye Of Adam.
- Master of Unlocking: Inherited by her expert locksmith father.
- Meaningful Name: Mitzi is a German name that means "bitterness", which seems like an Ironic Name due to her up-beat and kind nature, until you consider her backstory and her desire to kill The Eye of Adam. Her last name Hunt is also very appropriate, as she is 'hunting' down The Eye of Adam.
- Nice Girl: One of the most compassionate characters Susan meets, who cares deeply for her new friend and hopes to help her overcome depression.
- Perky Goth: Subverted. Her style leans to dark, and she's plenty chipper, but she rejects being labelled as part of any sub-culture.
- Red Herring: Chapter 4 introduces her as a kind and understanding individual much like how the First Parasite, Doctor X, was in his introduction. Then, just as Susan is about to decide whether Mitzi can be her lodger, the Queen of Maggots materialises behind Mitzi and ominously gives her a kiss. Shortly after Susan's outburst about this, it's then revealed that the Queen of Maggots didn't appear to proclaim that Mitzi is the Parasite she's after, but because she has given Mitzi a "kiss of death". In other words, she's dying of a terminal illness.
- Secretly Dying: Is dying of cancer. Her final duty before her time is up is to locate The Eye of Adam, the one responsible for pushing her boyfriend to commit suicide after he'd fallen into depression over her cancer, and kill him.
- Stepford Smiler: As the story progresses, it becomes clear that Mitzi's optimism and light-hearted nature is a facade to hide her anger and vengeful desire to avenge the death of her boyfriend.
- Suicide Pact: Her boyfriend Jack tried to persuade Mitzi into creating a suicide pact with him after discovering her terminal disease that would kill her in less than a year, and set up a plan for them to die in a car full of gas. When she refused, he held up his end of the pact.
- Supreme Chef: At least when it comes to pancakes.
- Took a Level in Jerkass: Becomes notably more aggressive and rude in Chapter 6 when tracking someone down in the apartment complex, which is surprisingly out-of-character for someone as kind-hearted as Mitzi. Considering that the Eye of Adam is responsible for driving her boyfriend to suicide, it's not surprising that Mitzi is feeling more impatient and vengeful the closer she gets to her boyfriend's killer.
- You Killed My Father: She is hunting the Eye Of Adam to avenge her boyfriend.
The CatsSusan's cats are the only friends she had before and during her suicide. They care deeply about her, despite being strays, and have important roles in the main storyline.
- Action Pet: They are instrumental in freeing her from the Second Parasite's grasp and killing the Fourth Parasite.
- Cool Pet: Despite the flack her neighbors often give her for having them around, they often fulfill this role, especialy when they save Susan and Mitzi's lives.
- Killer Rabbit: The Fourth Parasite found this out the hard way.
- Heroic Dog: The cat version of this.
- I'm a Humanitarian: They kill and eat the Fourth Parasite.
- Loyal Animal Companion: Will follow Susan anywhere, even in the depths of a cannibalistic pest control worker's home when she's in trouble. They were heard by Mitzi to be crying and howling out in sorrow when Susan killed herself, and they were even there for her when she did the deed, especially Teacup, just so she wouldn't be alone. And as the Fourth Parasite discovers, Susan's cats are more than willing to kill if it means protecting their master.
- Music Soothes the Savage Beast: They come calling whenever Susan plays that piano.
- Team Pet: Goes without saying.
The Parasites **SPOILER CHARACTERS**
- Arc Villain: Each Parasite is the Big Bad of their respective chapter, though the Eye Of Adam's influence is felt from Chapter 4 onward.
- Ax-Crazy: The particular brand and degree of sanity varies, but none of them are in their right minds.
- Big Bad Ensemble: There are the primary threats of the game, and with the exception of the Second and Third Parasites, who are a couple, they are all unrelated to each other.
- Serial Killer: They all count as this. The Eye Of Adam is more of a serial suicide-inducer, but he is still considered this.
- Walking Spoiler: The reveal of a Parasite is a big surprise.
Doctor Xavier Zelmann / Doctor XThe psychiatrist who cares for Susan after her suicide attempt. However, he is actually a sadistic Serial Killer who makes victims of his fellow staff and patients, takes them in body bags into a hidden facility in an abandoned part of the hospital, and tortures and murders them with the goal of recreating pieces of Renaissance-era art with their corpses. He is the first parasite, encountered during Chapter 2.
- Create Your Own Hero: Had he simply let Susan go in the first place, given that her version of Liz's death does not at all coroborate with how Zelmann killed her anyways or even implicate him in any way, he could've kept going on with his sadistic and depraved killings and "art portrayals", the evidence of which would've ultimately been buried when that part of the hospital gets demolished. Instead, his paranoia causes him to have her Killed to Uphold the Masquerade, which bites him in the ass when it turns out she's immortal and now seeks revenge against him.
- Impaled with Extreme Prejudice: If Susan uses the makeshift spear to kill him rather than the mace, he's impaled through the neck.
- Jerkass Has a Point: He's a genuinely proficient therapist, and his sessions with Susan actually help her. It doesn't change the fact that he's a depraved murderer.
- Karma Houdini: If you answered all of Liz's questions correctly, you'll find a key in her pocket that gives you the option to escape the building, with X still alive. Eventually, that part of the hospital will be demolished, and all the evidence of X's sadism will be buried.
- Karmic Death: If Susan kills him, he is either Impaled with Extreme Prejudice or struck by a saw-blade mace.
- Loves the Sound of Screaming: And actually wears a blindfold while tormenting a victim so as to better concentrate on the sound.
- Mad Artist: Recreated several pieces of Renaissance-era art with the bodies of his victims and compares a woman's screams to "poetry without words".
- Mad Doctor: Doctor Xavier Zelmann, PhD. His degree is on the wall of his office. Quite good at his work, as evidenced with his discussion with Susan. Also an insane killer who enjoys listening to the sounds of women's screams and then recreating Renaissance-era art with the bodies of his victims, comprised of patients and staff at the Cedar Lake Hospital.
- Nothing Personal: He tells Susan that he would have let her go if it wasn't for Liz.
- Obviously Evil: Most players pin him as the First Parasite upon his introduction.
- Soft-Spoken Sadist: He speaks with a soft voice and enjoys tormenting young women, something he learned to do as a psychiatrist.
- Wicked Cultured: Has stated that all art should be appreciated, no matter how it is created, and has a taste for Renaissance-era art. He enjoys it enough to try and recreate several pieces of art with the corpses of his victims.
Pest Control ManAn unnamed man working as a pest control worker. He works in tandem with his wife Gladys, who is the third Parasite, to abduct, torture, and eat innocent people. He and his wife are encountered in Chapter 4.
- Extreme Doormat: Implied. He appears to do everything his wife asks him, up to and including putting his gas mask in his van like she asks him.
- Gun Nut: Owns a collection of guns. He leaves his favourite pistol behind for Susan to kill herself after she is blinded, not knowing that she is functionally immortal and can come back with her sight intact. His shotgun is also taken from him by Susan after his death and used to kill his wife.
- Henpecked Husband: Though her love for him seems genuine in a twisted way, his wife seems to be the more dominating person in their relationship.
- Hoist by His Own Petard: Susan uses his pesticide to create a Deadly Gas with which she poisons him, and she wears his gas mask to protect herself while she does it.
- I'm a Humanitarian: Just like his wife, he is a cannibal.
- Karmic Death: Susan fills his room with toxic gas.
- Kick the Dog: He leaves his pistol for Susan to kill herself after Gladys blinds her, but purposefully leaves it just out of reach.
- Malevolent Masked Man: While wearing his gas mask.
- Near-Rape Experience: He assaults and nearly rapes Susan before his wife bursts in. Disturbingly, Gladys takes this is a seduction attempt on Susan's part.
- Not Quite Dead: When Susan walks into his gas-filled room, he briefly rises from the ground and grapples with her for his gun. She knocks him down, and he immediately succumbs thereafter.
- Unholy Matrimony: He and his wife are very much in love, and they're both depraved cannibals.
GladysA disturbed, controlling housewife and cannibalistic serial killer. She is married to the Second Parasite, and they are both encountered in Chapter 4.
- All There in the Manual: Unlike her husband, her name, Gladys, is stated in the game's end credits.
- An Axe to Grind: Almost never seen without her meat cleaver. If Susan runs into her without a weapon, she gets hacked to death.
- Dull Surprise: Despite Susan being supposed to be blind or dead at the time, the wife seems rather unsurprised to see her walking about, not that it helps Susan's case.Gladys: Look what the cat's dragged in... Again.
- Expy: According to Word of God, her character is intended as a reference to Nurse Edna from Maniac Mansion.
- I'm a Humanitarian: Like her husband, she is a cannibal. She takes the more proactive role in this, killing and butchering the victims her husband drags in.
- Karmic Death: Susan shoots her in the chest with her husband's shotgun after she ambushes Susan in the yard.
- Larynx Dissonance: She's voice by a man trying to imitate a female voice... and it shows, making her even more creepy.
- Non-Standard Character Design: Unlike every other human character, she has constantly bloodied skin that looks almost decayed, and she walks with a distinct Zombie Gait.
- Unholy Matrimony: She and her husband are very much in love, and they're both depraved cannibals.
- Yandere: Sees any women speaking with her husband and assumes they're trying to seduce him. She's violently protective of their relationship. When she thinks Susan tried to seduce her husband, she pours bleach in her eyes.
- Zombie Gait: She walks around in a very strange and disturbing way.
The CarpenterUnlike every other parasite, nothing is known about this man. He shows up at Susan's door in Chapter 5 with flowers, then bashes her and Mitzi in the head with a hammer and duct tapes them both in the bathtub with the intent to hang Mitzi and force Susan to play the piano.
- Cutscene Boss: Susan doesn't have to do anything for him to wind up dead.
- Drop the Hammer: His weapon of choice.
- Foreshadowing: Heavily implied to be Susan's stalker, who sent her flowers once a week.
- If I Can't Have You...: If he was Susan's stalker as is possibly implied, he most likely visited Susan's flat for the purpose of murdering her for rejecting his love.
- Karmic Death: Susan's cats kill and eat him.
- No Name Given: However, he is referred to by Remigiusz Michalski as the "Carpenter".
- Outside-Context Problem / Diabolus ex Nihilo: Unlike every other Parasite, he has no clear ties to the story, simply showing up at Susan's door at random and taking her and Mitzi hostage for nebulous purposes. He might be Susan's stalker, but this is never determined.
- Self-Disposing Villain: Forcing Susan to play the piano attracts her cats, which attack and kill him.
- Small Role, Big Impact: Nothing is concretely known about him and his arc is the shortest of all the Parasites, but his actions give Susan the presence of mind to finally fill Mitzi (and the audience) in on her past, and the encounter firmly solidifies Mitzi as Susan's best friend.
- Moreover, if he is Susan's stalker as it is implied, then his habit of sending her flowers every week makes him the indirect cause of Zoey's death, Eric's suicide and Susan's depression.
- The Unfought: Unlike every other Parasite, he is not directly hurt by Susan or Mitzi; instead, while the women are both in danger, Susan's cats jump out of nowhere and tear him to pieces.
- The Unintelligible: He only communicates by screaming/roaring, as if incapable of real speech.
- Unwitting Instigator of Doom: If he was the stalker, he sending flowers to Susan is what indirectly caused her daughter's death, the point where Susan's life went downhill.
The Eye of Adam / Adam
The fifth and last parasite, encountered in Chapter 7. A spiteful person who tempts people into suicide using an Internet forum, he relies completely on his father to take care of him as his body is completely paralyzed except for his eyeball. Using a computer controlled by his eye movements, he is able to communicate and control various things in his apartment. He convinced Mitzi's boyfriend Jack, who was devastated when he heard of her cancer, to commit suicide by inhaling hydrogen sulfide. Though he failed to convince her to do so with him, Jack killed himself in his car. This led Mitzi to devote her last months of life to hunting him down.
- And I Must Scream: His fate after being disconnected from his computers and presumably being sent to a nursing home for the rest of his life.
- Big Bad: More from Mitzi's perspective than Susan's, as his connection with her is more personal, as he is the one that caused Mitzi's boyfriend to commit suicide out of grief upon discovering that his girlfriend is terminally ill.
- Cruel Mercy: Should Susan stop Mitzi from killing him and prevent the room from exploding, they leave him alone without any more assistance due to his only living relative being dead, and it is assumed that he is taken away into a nursing home under constant surveillance, where he will never see a computer screen again.
- Death Seeker: He leads Mitzi to his apartment so that she can kill him. However, he isn't planning on dying alone.
- Evil Cripple: Is completely paralyzed, leaving him incapable of doing anything except moving his eyeball in order to use an eyepiece that directly controls the computer.
- Fate Worse than Death: He suffers this if Susan convinces Mitzi to spare him. See Cruel Mercy.
- For the Evulz: He drives people to suicide because he just wants everyone to die.
- Manipulative Bastard: His MO is convincing people to kill themselves.
- Meaningful Name: Because he is paralyzed, his eye is all that is left of him, thus the name 'The Eye of Adam'.
- Never Hurt an Innocent: Instructs his victims on ways to end their lives while ensuring that nobody else will get hurt in the process. It's not clear if this is out of principle, or simply to avoid drawing attention to himself. Mitzi implies that this just part of his ideology, knowing his victim died willingly.
- Overarching Villain: Unlike the other parasites, Adam's influence begins to be felt throughout the story after Mitzi joins Susan.
- Patricide: He floods the apartment with toxic gas, killing his father. This comes back to bite him if he fails to convince Mitzi to kill him and set off a leaking oxygen gas that will also kill her as well.
- Strike Me Down: He spends his entire "conversation" with Mitzi ordering her to pull the trigger.
- Taking You with Me: Taunts Mitzi into pulling the trigger on him, which would result in the room going up in flames due the gas leak, thus allowing him to get the last laugh. It's up to Susan whether she goes through with this or not.
- Troll: He takes pleasure in pushing people into killing themselves, very much like how an internet troll would continuously torment others for their own amusement. This is what motivates Mitzi into seeking him out and confronting him in person. Even with a gun aimed at his face, he continues to goad Mitzi into killing him while ensuring that Mitzi's shooting him dead would result in her death as well.
- Walking Spoiler: As the final Parasite and the subject of Mitzi's entire character arc, he is ironically this even more so than the regular Parasites.
The Queen of MaggotsA mysterious old woman who appears in the afterlife to grant Susan Resurrective Immortality in exchange for becoming her executioner. She also appears in Downfall (2009) and Lorelai.
- A God I Am Not: She describes herself being as powerful as gods, never claiming to be one herself. She also explicitly says that she is not Death, and that she's dead just like Susan.
- Ambiguously Evil: On one hand, she seems to have genuine sympathy for Susan. On the other hand, Susan identifies her as the voice of depression in her life, and she doesn't deny it. On the gripping hand, the quest she gives Susan, and her actions in Downfall (2009) seem to imply she has a distaste for murderers. On some kind of fourth hand, the immortality she grants Susan comes at the cost of other people's lives. Some of the people were going to die anyway, but still...
- Anthropomorphic Personification: It's heavily hinted at that she's depression incarnate. Susan, at least, comes to this conclusion in the end. In Lorelai, the Queen reveals that she was born out of darkness to burrow her tunnels deep in the wicked human hearts, technically making her the embodiment of evil and depression.
- Black-and-Grey Morality: Dark, dark, dark Grey to the Parasites' Black, if it's not outright Evil vs. Evil.
- Didn't Think This Through: While recruiting Susan as her personal vanquisher of Parasites whether she likes it or not, she demands her to stand up for herself to instill the right mind-set to be her personal hitman. The player can choose to have Susan oblige...by standing up to The Queen of Maggots herself and defy her wishes in every step of the way. This becomes a crucial point later on as continuously defying The Queen of Maggots is what leads the player closer towards the best ending in the game, provided that all other key choices are made as well.
- I Have Many Names: She doesn't much care what the living call her, but there's one sobriquet she's particularly fond of.
- Jerkass: Though she initially appears to be comforting and understanding to Susan's plight, she's also shown to be cruel and spiteful to keep her in line, often inappropriately reminding Susan of the terrible things in her life, even gleefully asking whether it was fair that Susan's daughter passed away due to a rare pollen allergy while Susan and her husband were having an argument outside her bedroom.
- Kick the Dog: She often delights in making Susan miserable to prove a point, especially when she nearly tricks Susan into thinking that Mitzi is a murderous Parasite in their first meeting.
- Manipulative Bastard: She is the one who actually pulling the strings of depression on the mortal realm, playing dreadful games of destiny and tricking humans into it.
- Names to Run Away from Really Fast: Especially when she emphasizes the fact that maggots feed on the dead. Not something that's going to put a newly dead person at ease. Subverted in Downfall, assuming she's telling Agnes the truth about her true name being Lorelai, which Agnes instead finds "pretty". "Lorelai" is also the name of Harvester's upcoming game, the final entry in the "Devil Came Through Here" game trilogy so far comprised of Downfall and The Cat Lady.
- Not So Different: Claims that she knows how Susan feels, because she herself felt that way for a long time.
- Our Demons Are Different: She looks exactly like an old human lady, albeit creepy and ghostly. Her true form is actually a gigantic monster with huge maggot-like tentacles, snacking dead corpses.
- Poisonous Friend: She presents herself as Susan's ally, and maybe she even believes that she is. Nonetheless, her warped worldview and sadism cause her to lead Susan to some very nasty (and excruciatingly painful) situations.
- Psychopomp: While she claims not to be the personification of death, she at least has some power over the threshold between worlds. There's also her sudden appearance behind Mitzi, who is dying of cancer. It might have been an attempt to freak Susan out, or it might have just been a result of Mitzi's proximity to the realm of the dead.
- Satanic Archetype: A ruler of an unpleasant afterworld, she grants you immortality in exchange for the sacrifices of human souls and given you the task of killing evil psychopathic murderers and manipulating the lives of depressed people. She is in fact the Devil herself, or at least the closet equivalent to it.
- Unexplained Accent/What the Hell Is That Accent?: For bonus points, the accent disappears whenever she's calming Susan down.
- Villain Protagonist: In the new game Lorelai, you will play as a young woman with a red flower on her hairs who named Lorelai. She is believed to be the Queen of Maggots herself before she get screwed up.
- Averted: it turns out the Lorelai controlled by the player is a different person and yet another victim of the Queen of Maggots. Although she tells Lorelai that she plans to turn her into the next Queen of Maggots and, near the end of the game, she does appear to Lorelai looking just like her. However, since she's associated with depression, her using Lorelai's appearance could be simply an indication that part of her will always live on within Lorelai.
- Well-Intentioned Extremist: Though it's not entirely clear why she brings back Susan to life for the purpose of becoming her executioner, and is rather intent in making sure that Susan follows her role by granting her immortality whether Susan wants it or not, she does seem to want to see the Parasites punished for their sins.
EricSusan's ex-husband. In his only appearance during a flashback, his jerkassery inadvertently caused the death of his and Susan's child.
- The Alcoholic: Is a frequent drinker, and drank himself to death over the loss of his daughter.
- Driven to Suicide: After his daughter's death.
- Green-Eyed Monster: Is implied to be jealous of his daughter Zoey over how Susan pays more attention to tending to the baby's needs than her husband. It's his jealousy that causes him to stop Susan from checking up on their daughter in the middle of their argument, which accidentally stops Susan from noticing how their daughter was slowly dying from a rare pollen allergy from the flowers left in her room.
- Hate Sink: He's certainly not winning husband-of-the-year awards anytime soon, considering his treatment of Susan and his implied jealousy of his daughter.
- It's All About Me: Criticizes his wife for not being supportive enough to her husband's needs, and considers Susan to be 'lazy' due to not making enough time for both their daughter and her husband after work hours.
- Jerkass: One of the most unpleasant characters in the game, and he isn't even one of the main antagonists.
- Posthumous Character: He died months before the game's start.
- Stay in the Kitchen: He seems to have this mindset, even with Susan already being a stay-at-home mother, as some of his arguments during the big fight descend to "not having dinner ready for him when he gets home" levels.
LizElizabeth, also known as Liz, is a nurse at the Cedar Lake Hospital who watches over Susan during her recovery from her attempted suicide. A very talkative person who often gets carried away in conversations, she dislikes the hospital because she feels trapped there.
- Dead All Along: Hard to tell how long, exactly; when Susan finds her corpse, it seems she's been dead since before her apparent suicide, but by that point Susan's been drugged up so often that the passage of time is uncertain. It also interesting to point out that Susan ask of Liz to the hospital staff, and they don't seem to know her at all, aside from Doctor X for some reason...
- Driven to Suicide: Jumps off the roof of the hospital in front of Susan, regardless of how well she tries to convince Liz not to.
- Genki Girl: She's very friendly and animated. It's all an act. She's actually severely depressed.
- Naughty Nurse Outfit: Tried it once for her boyfriend, but neither of them were really into it.
- Not So Different: Is also suicidally depressed, just like how Susan was before she was resuscitated in the hospital.
- Spirit Advisor: Possibly. She has been dead for a while by the time her corpse is found, but she appeared to Susan trying to warn her about someone wanting to hurt her. As she was already dead at that time, she may have been referring to Doctor X, and if Susan answered all of her questions correctly she has a key to the facility exit in her pocket, possibly her intending for Susan to escape and leave forever.
BryanA neighbour in Flat 6. He detests Susan with a passion.
- Butt-Monkey: In the Cat Widow segment, he finally gets put through the wringer by Susan.
- Hair-Trigger Temper: A simple short piano melody in the middle of the night is enough to send him down to Susan's door and shout at her for waking him up. It's also implied by Susan that Bryan has anger issues and usually use whatever excuse he finds to shout at people, no matter how small.
- Hypocrite: Angrily calls out Susan for waking him up in the middle of the night when she plays the piano to call her cats over for company. He also doesn't seem to care that he is disturbing the other neighbours by shouting at Susan in the middle of the night, and seems more concerned about getting even with Susan.
- Irony: Calls Susan a 'nutcase' at one point, while completely oblivious to the fact that he has been living on the same floor as The Eye of Adam, a dangerous Parasite who has been goading many victims to commit suicide on suicide help forums.
- Jerkass: One of the meanest people in the game who isn't a sadistic killer. He's introduced by harshly scolding Susan for playing the piano in the middle of the night, which accidentally woke him up. He goes as far as to threaten to call pest control to get rid of her friends, and throws one final insult at her even if Susan tries to be apologetic to him. His treatment of Susan is so harsh, he can cause Susan to undergo an emotional breakdown if she is already too stressed out beforehand.
- Laser-Guided Karma: The comeuppance he gets in the "Legend of the Cat Widow" scene is a thing of beauty.
- Not So Different: He has quite a bit in common with Susan, considering that he too lives alone, doesn't seem to have many friends, and has problems with interacting with other people as well.
- Porn Stash: After invading his flat, Mitzi mentions that he was a lot of pornography in his laptop.
- Unwitting Instigator of Doom: He calls up the Second Parasite when he makes good on his threat to call Pest Control on Susan and her cats, resulting in Susan's kidnapping.
Old ManAn kind yet eccentric elderly man who lives in Flat 5. He is actually faking his dementia and is the father of The Eye of Adam.
- The Atoner: Is deeply ashamed of what his son has become, and wants to set things right by helping Susan and Mitzi confront his son.
- Cloudcuckoolander: Has dementia, and tends to be an oddball at times. Subverted, it's an act.
- Even Bad Men Love Their Papas: Inverted. Until the very end of the game, he was taking care of his son and providing everything he needed, even knowing he's a serial killer. Although, he probably did it more because of fear than because of love.
- Evil Old Folks: Is assumed to be The Eye of Adam, or in cahoots with him, but it turns out to be subverted. See The Atoner.
- Tempting Fate: Assumes that his son would not kill his own father due to how much his father helped him due to his condition. Tragically, he's wrong.
- Rambling Old Man Monologue: Tends to go off on monologues about his wife at times. He's just trying to distract Susan and Mitzi.
- Redemption Equals Death: He finally gets up the nerve to stop helping his son, and it costs him his life as his son has him killed for his betrayal.
- Ax-Crazy: Obviously, given that he'll eventually go on a murderous rampage.
- Boom, Headshot!: How he kills Susan in the hotel sequence.
- Karma Houdini: He receives no punishment for his actions in this game, at least. In fact, in the Downfall (2009)} remake, he only gets killed in the non-canon negative ending — both others see him on the run with Ivy, whether she's alive and grateful (the Golden Ending) or dead and rotting (neutral).
- Previous Player-Character Cameo: You play as him in Downfall (2009).
- Red Herring: His interactions with Susan imply that he is one of the parasites, but he isn't... at least not in this game.
- Room Full of Crazy: His apartment is creepily lit and contains a shattered mirror, a knob-less door painted with the Number of the Beast, and a bathroom with a mannequin in the tub.
PaulineA young mother who lives in Flat 8.
JesseA young man who lives in Flat 7.
- Nerd: Hinted at by his appearance and the elaborate gaming rig set up in his apartment.
- Nice Guy: Is one of the few residents who doesn't detest Susan and is generally pleasant towards her. He even volunteers to buy a new cable and fusebox for the apartment during a black out, reassuring Pauline everything should be fine tonight.
Rita TickleA member of a babysitting agency sent to Pauline's apartment to care for her baby. She interferes with Susan and Mitzi's search of Pauline's apartment during the hunt for The Eye Of Adam.
- Hate Sink: Stubborn, rude, has an obnoxious voice, and holds that anybody who puts a baby up for adoption is going to Hell. There's not much about Rita that isn't meant to make you detest her.
- Spanner in the Works: A mild case; she interferes with Susan and Mitzi's plan, but not a degree that it doesn't ultimately work.