The principal antagonist of the Dr. Crafty series, Dr. Mindstein is the diabolically depraved source behind the major events of the main story, starting with the end of Season 2's finale. Unlike Crafty himself, Mindstein plays the role of a Mad Scientist as straight as possible, and she proves it through her villainous experimental endeavors. She plans to one day gain access to powers that would help her create an unrivaled deity for the sake of scientific discovery, hoping to leave behind a legacy for herself, and refuses to cease planning until she finally achieves such a dream.
Worse still, Mindstein is the abusive mother of Nurse Worse and Screw. She harshly experimented on them both throughout their childhoods, even up to their early adulthoods. Because of her, the two sisters ultimately turned into the Frankenstein monster girls that they are today. Nurse thankfully escaped some time ago, but Screw wasn't so lucky.
- '50s Hair: She has a notable bouffant hairstyle that's much larger than her head.
- Abusive Parent: To Nurse. One flashback shows her cutting into Nurse's body while she's still awake, and in the present, she's responsible for getting Nurse possessed. Furthermore, other flashbacks demonstrate that one punishment for Nurse leaving the house without her mother's permission is a syringe to her neck. All of this because she doesn't see Greta as a daughter, but as a scientific tool to further her research.
- Artificial Limbs: Reveals one in "I Need a Hero Academia," complete with a giant syringe. It's somewhat ambiguous if Mindstein truly has them, as the one that did was fully robotic.
- Astonishingly Appropriate Appearance:
- Her Spikes of Villainy are incredibly thin, almost syringe-like. Fittingly, Mindstein uses syringes for both combat and her physical abuse sessions.
- Her hairstyle makes her head appear larger than it truly is, especially when she's silhouetted. It also bears two electrical patterns that converge toward her domed, exposed brain. Both qualities, in tandem with her use of electric attacks, greatly emphasize her genius and how much pride she holds for it.
- Ax-Crazy: Regularly partakes in torture and mutilation, all with a perky smile on her face.
- Berserk Button: Past her ambitions for godhood, Mindstein loves being in control of any situation or relationship that she's a part of. If her feelings of control are threatened in any way, she lashes out — hard.
- When she finally has Nurse restrained in "I Need A Hero Academia," she formally introduces herself by slapping her daughter across the face and shocking her, eventually triggering Nurse's PTSD — all because Nurse eluded Mindstein's control for so many years. When Crafty and Class 1-A come to Nurse's rescue, Mindstein once again slaps Nurse when she calls out for Crafty in delight. At that very moment, Mindstein realizes the threat before her, and she takes out her frustrations about it on the easiest and closest target.
- In "We're Back! A Crafty Story," a sudden, taunting message from the Crafty Crew causes Mindstein to lose her cool and break her computer. Two episodes later, "Player Select" implies that she immediately started preparing a new attack plan. And it's ready by "Old Project, New Look" — the very end of Season 4's second month. It's notably the soonest that Mindstein has ever been ready to strike in a single season.
- Big Bad: This is not a well-crafted persona; Mindstein is a legitimate Mad Scientist. She's the over-arching villain of the whole show thanks to the deeply personal connection she has with Nurse and the Infinium Relics.
- Brain in a Jar: Her brain can be seen through a glass dome on her forehead. Its purpose was to keep her alive while she upgraded her body, but that wasn't quite enough for her.
- By the Lights of Their Eyes: Her eyes are always visible with a disturbing blue glow. They're even visible in her shadow, giving it an even more disturbing effect.
- The Chessmaster: By studying every episode Crafty releases, she came up with a clever plan to capture the castle with little resistance, kicking off the plot of "I Need a Hero Academia." She made sure to have Screw give Crafty a Megaton Punch to get him as far away from the castle as possible, knowing about Sasha's possession of his body and not wanting her to meddle in her scheme. As for the other co-hosts, Mindstein had her Doc-Drohnes launch the assault quickly to get past Crystelle's clairvoyance and electrified the dungeon bars so neither Pepper nor Messi could squeeze through them. And that's not even accounting for the robot clone of herself she sent to attack the castle in her stead. The true Mindstein stays in her laboratory, studying the outcome of the subsequent fight.
- Deal with the Devil: And despite her plans also involving a Physical God, she's the devil of this deal! In this instance, she "convinced" Bill Cipher to work for her and extract an unknown secret from Crafty's mind.
- The Dreaded: Just the mere mention of her name makes Nurse react in fear and for very good reason. Nurse completely froze when Mindstein raided the castle, leaving her completely defenseless as Screw effortlessly knocked her out.
- Dr. Fakenstein: Between her name, her depiction as an evil scientist, and being the mother of two Frankenstein monsters, Mindstein pretty much fits the bill. She also incorporates some elements of the Monster herself with her blue skin and stitches.
- Evil Counterpart: The similarities aren't quite as pronounced as those between Nurse and Screw, but Mindstein is an eviler answer to Crafty. Both are tall, thin Mad Scientists who revel in their villainy and are accompanied by a short, plump assistant. However, Crafty is a fundamentally good person acting the part of a mad scientist — Mindstein is the genuine article, and she's absolutely rotten to the core.
- Evil Is Bigger: Among the cast members with typical human proportions, Mindstein is one of the tallest characters on the show. Discounting her hair, she only slightly surpasses Pepper's overall height. However, Mindstein's eye level sits much higher than Pepper's — As shown in this height chart, Mindstein's sits right at the seven-foot mark, while Pepper's is just above the six-foot mark. Thus, Mindstein seems even taller by comparison.
- Evil Laugh: She pulls off a few disturbing ones, mainly during the Season 3 trailer and after she successfully takes over the castle.
- Evil Matriarch: She's Nurse Worse's mother and she's bad enough to bend at least two villains from other shows to her will.
- Faux Affably Evil: Mindstein barely puts forth a veneer of motherly politeness, which she gleefully drops the moment an opportunity presents itself. This aspect of her character is showcased when she and Crafty meet for the first time in "Magic Kingdom Mania." She thanks Crafty for taking care of her daughter... before immediately siccing her other daughter on them them to initiate her takeover of the castle. Later, "I Need a Hero Academia's" first part houses a scene where Mindstein holds a moderately polite conversation with the captive Nurse ... in between prolonged denigration and harsh (sometimes electrified) slaps to the face.
- First-Name Basis: Mindstein generally makes a point to address Nurse by her real first name: Greta. It's meant to be disrespectful; Mindstein does so simply to exert control over her daughter, to remind her of her time before Crafty. However, with Hazel, the opposite is true, with Mindstein only ever addressing her by her current alias: Screw. In this case, she's subtly upholding the idea that their relationship is strictly professional. Screw reciprocates by only addressing Mindstein as her "master." The only time Mindstein explicitly acknowledges Screw as her daughter is in "Something Weird This Way Comes," just before Mindstein introduces the Infinium Flute to Bill Cipher.Mindstein: "Oh, Screw, darling~? Can you bring mommy's new toy~?"
- For Science!: Her justification for all the horrid acts she's committed, and the backbone behind all of her schemes.
- Greater-Scope Villain: Of "The Foreshadow Game" and the Cartoon Month episodes, being the one who Zorc and Bill Cipher after Crafty and friends in the first place.
- A Glass of Chianti: She's sometimes depicted holding a glass of a blue cocktail.
- Godhood Seeker: Her ultimate goal: using Nurse Worse and all of the Infinium Relics, she wanted to open the Infinium Door and let the eldritch energy flow throughout the multiverse, with herself at the center of it all researching the results.
- Hijacking Cthulhu: So far, she managed to get two Eldritch Abominations with immense power to work for her, while suffering no retaliation from them! And, as noted above, she plans on doing this with the Infinia too.
- Icy Blue Eyes: She has pale blue eyes, which is fitting for her cold, sinister personality.
- Improbable Hairstyle: Mindstein bears an impressively large bouffant. Strangely, all of it is somehow distributed behind her head, seemingly to make her domed brain that much more visible.
- Just Toying with Them: While Mindstein could feasibly confront the Crafty Crewmates whenever she wants, she likes screwing with them by knowingly, mockingly integrating her plans into their show's monthly themes.
- For her first malicious act on the show in the present day, she sends Yami Bakura to possess Nurse, right in time for Season 2's Yu-Gi-Oh Month. The month begins with "Best Yu-Gi-Oh Monsters," with Crafty and Messi conducting business as usual before Bakura starts making things go wrong at the end.
- When Mindstein successfully steals Crafty's Castle in "Magic Kingdom Mania" — the final episode of Disney Month — she caps off her attack with a bastardized Walt Disney quote. During the ensuing Hero Month, Mindstein stores the captive Nurse in a giant device reminiscent of one from the month's source material.Mindstein: "I hope we all don't lose sight of one thing: It all started... with me."
(Mindstein laughs uproariously as the episode closes...)
- In Season 4, she holds off on sending out Metal Crafty, a blatant reference to Metal Sonic, until Sonic Month arrives. Metal's behavior throughout the month implies that Mindstein derived some of his abilities from Metal Sonic's Sonic Heroes incarnation. Metal spends some of the month scanning the spin-off hosts's DNA to gain their abilities, exactly as Metal Sonic does in that game.
- Karma Houdini: Since she was in her lab the whole time during "I Need a Hero Academia," she was never in any danger of facing Crafty and Class 1A and managed to get away scot-free to continue her schemes.
- Knight of Cerebus: The show's previous villains were either harmless or hilarious. But the instant this lady appeared, she established early on that she means business.
- Large and in Charge: She has a powerful Frankenstein Monster and killer robots to serve her, and according to the official height chart, she towers over most of the cast at 7' 5".
- Laughing Mad: Mindstein cackles more and more as her schemes in "I Need a Hero Academia" fall apart thanks to Crafty and Class 1A. Of course, that was just the duplicate. Following its demise, the real Mindstein claims the cackling is a quirk in its design, and that she herself doesn't laugh nearly as much under pressure.
- Lean and Mean: In contrast to her pudgy and kind-hearted daughter Nurse Worse, Mindstein is as thin as she is evil.
- Mad Doctor: An expert in medical science and anatomy, and an insane murderer with delusions of playing god.
- Morally Ambiguous Doctorate: Even more so than Crafty himself!
- Non-Action Big Bad: It was revealed to be the case in "I Need a Hero Academia" as the Mindstein Crafty and the others defeated was a robot clone, while the real Mindstein spent the story arc watching the events unfold from the safety of her own lair.
- Obviously Evil: Just look at her! Her design makes Crafty look subtle in comparison!
- Offing the Offspring: In order to turn her daughters into Frankenstein monsters, this trope naturally comes into play.
- Playing with Syringes: Her experiments involved murder, mutilation, and playing with forces she could not comprehend, all just to devise the ultimate tool for conquest and research.
- Purpose-Driven Immortality: In her case, her purpose is to become truly immortal, not just a simple brain continually sustained via replacement bodies and upgrades. And to get that, she seeks the powers of the Infinia and the secrets of the universe.
- Psycho Electro: Able to produce electricity from her hands, mainly for Electric Torture and Mind Raping.
- Really 700 Years Old: Her pursuit in scientific studies has led her to be alive for hundreds, maybe thousands of years. It wasn't enough for her, as she knew she'd die eventually no matter how long she's lived for.
- Red Oni, Blue Oni: The Red to Screw's Blue. While Screw is eerily calm with a monotone pitch in her voice and barely any expressions coming from her face, Mindstein is much perkier and has her face locked in a near-constant smile.
- Scary Stitches: Comes with the territory of being a Frankenstein monster, but unlike Nurse Worse she's truly scary.
- Silence, You Fool!: Prone to shout this at Nurse for speaking and for singing. It's unknown if the real Mindstein would do this as much as her more unstable clone, but it's likely she would.
- Sinister Silhouettes: Up until Episode 70, she was obscured in shadow. Only her eyes, mouth, brain, and the faintest details of her clothes could be seen.
- Skunk Stripe: She's got two blue streaks in her hair, similar to the Bride of Frankenstein.
- Slasher Smile: She must really enjoy her evil schemes as she's prone to this quite often, usually when torturing her victims.
- Spikes of Villainy: She has spikes on her gloves, boots and sides of her head.
- Vile Villain, Saccharine Show: Considering her Establishing Character Moment involved mutilating her daughter, it's pretty safe to say she's much viler than all the show's other characters!
- Villainous Breakdown:
- Throughout the last part of "I Need a Hero Academia," seeing the power of the Relics used against her caused her to lose quite a few more screws than she already had. This was noted by the real Mindstein to be a trait more associated with her robot clones, but the point still stands.
- Later, Mindstein has a small breakdown at the end of "We're Back! A Crafty Story!" As usual, she's watching Dr. Crafty to study up on her opponents. What she doesn't expect is when Crafty, Nurse, and their friends directly addresses her and dares her to attack again. Their boasts actually strike a nerve; Mindstein silently tosses a scalpel into her screen and breaks it, visibly outraged that her targets are no longer afraid of her. Notably, unlike the Mindstein who broke down in the Season 3 finale, this one is the real deal.
Mindstein's younger daughter and right-hand assistant, Screw is a powerful Frankenstein monster girl who was introduced alongside Mindstein herself at the end of Season 2's finale, albeit as a silhouette. Unlike her older twin; Nurse Worse, Screw emotes very little and only seems to speak in a monotone manner. What she lacks in true emotion, however, she makes up for with high levels of raw strength and complete loyalty to Mindstein. This loyalty goes as far as having Screw address her mother as her "master" perpetually, although her true feelings towards Mindstein appear to be ambiguous.
- Always Someone Better: Agrees to Mindstein's 'upgrades' to not fall behind her sister, as seen in the post-credit scene in the Season 3 finale.
- Astonishingly Appropriate Appearance: Like Nurse, Screw happens to have discolored patches of skin. They're almost identical to her sister's — except the one on her face, which is mirrored. It subtly hints at how Screw is a dark reflection of what Nurse became.
- Ax-Crazy: While not as apparent as her mother, she does show shades of this, especially when she's in a fight and brutally beating someone to death.
- The Brute: Despite being quite intelligent, Screw chiefly acts as the brawn to Mindstein's brains. She's got more than enough power to spare for the role, something proudly demonstrated when she effortlessly trounces Class 1-A in "I Need a Hero Academia."
- Body Horror: Unlike Nurse, Screw only has one permanently attached bolt placed in her head. It's impaled all the way through her skull, with the tip poking out from the other side. However, the bolt has just enough clearance to turn, letting it serve as a dial that controls her power output.
- Cain and Abel: The Cain to Nurse's Abel. She doesn't hesitate to attack Nurse Worse on her mother's command.
- Cyborg: After her defeat, Screw returns to Mindstein's lair a bloody pulp...and with open wounds revealing metal instead of muscle, revealing the true extent of her mother's experimentations thus far.
- Dark Action Girl: She's shown to be just as capable a fighter as Nurse, easily knocking her out and sending Crafty flying out of the castle, both with a single punch. And that's not even getting into the Curb-Stomp Battle she delivers to Class 1A...
- Dark Is Evil: In contrast to the bright colors and clothes her sister and mother wear, Screw wears an all-black outfit with shades of dark red and pink, and her skin palette is a much duller gray.
- The Dragon: She's Mindstein's right-hand woman, always accompanying her in her schemes.
- Emotionless Girl: Even during her childhood, she almost never raises her voice, and her default facial expression is a dull frown.
- Evil Counterpart: Mindstein raised Screw to be her exact answer to Nurse Worse. To wit, Screw is also a plump Frankenstein monster in service to a mad scientist, one who's truly evil compared to Crafty. She also demonstrates what Nurse would become if she remained under Mindstein's control her whole life — whereas Nurse is exuberant and generally joyful thanks to her time with Crafty, Screw is, for the most part, an emotionless husk. To emphasize this idea, Screw's color scheme is identical to what Nurse's was before Mindstein started experimenting on her.
- Fat Bitch: She's just as big as her sister, but nowhere near as nice.
- Flesh Golem: Much like her sister, Screw is another Frankenstein's Monster-inspired monster girl, having the same discolored patches, just mirrored and under a different color palette. There's no word on whether she takes formaldehyde baths to maintain her body's quality, however.
- Given Name Reveal: As revealed in episode 65, Hazel.
- Laser-Guided Karma: Screw is responsible for sending Crafty flying across the globe in "Magic Kingdom Mania." She not only sends him exactly where he needed to be — right before the U.A. High School campus — but she suffers a similar defeat during the last part of "I Need a Hero Academia." Nurse Worse, Screw's Good Counterpart and older sister, delivers Screw a sound beating and tops it off with a Megaton Punch of her own, avenging Crafty and mirroring how the Season 3 finale started.
- Lobotomy: It's strongly implied that Screw became who she is today thanks to Mindstein tampering with her brain. Her relative lack of emotions, her straightforward, unenergetic manner of speech, and the screw impaled through her head are dead giveaways to such a fate. Mindstein also wordlessly reveals Screw's condition to Nurse at the end of their conversation in "I Need a Hero Academia" Part 1.Mindstein: "... Now that I have you back, I can finally correct this little mistake that you became. And my plans... can finally continue."
Nurse: "Plans...? What plans...?"
Mindstein, leaving the room: "Oh, you don't need to worry yourself with that. You won't have a mind to worry about anything, soon enough..."
(As Mindstein exits the lab, she passes by an awaiting Screw in a doorway. As if to illustrate her mother's point, Screw blankly stares at Nurse for several uncomfortable seconds. The sisters lock eyes, with the implications of Mindstein's threat slowly dawning on Nurse... Screw finally leaves, at which point Nurse breaks down.)
Nurse, sobbing: "Crafty... Help me... I need you...!"
- Meaningful Name: Her name comes from the screws lodged in her head and arms.
- Megaton Punch: She's strong enough to punch Crafty from his castle in Florida all the way to U.A. High School in Japan. That's about 7,300 miles away, just under a third of Earth's circumference.
- Muscles Are Meaningful: She gains a notable muscle increase when she turns her head screw and is practically a nigh-unstoppable fighter because of it.
- Not So Stoic: While normally emotionless, she becomes much more unstable and sadistic during a fight, even indulging in taunting her opponents with how she's going to destroy them.
- One-Woman Army: Best demonstrated when she takes down all of Class 1A by herself, even managing to Punch Catch one of Deku's strongest attacks.
- Power Limiter: The screw embedded through her head controls her power output. Quarter-turning it allows her to take down all of Class 1A in "I Need a Hero Academia," and half-turning it allows her to go toe-to-toe with Nurse's super mode in the same finale.
- Perpetual Frowner: Her default expression, even in flashbacks.
- Pintsized Powerhouse: Being Nurse's twin sister, Screw is identically short in stature. "I Need a Hero Academia" showcases how she's also quite a dominating presence in a fight, though when push comes to shove, Nurse is a step ahead of her.
- Red Oni, Blue Oni:
- The Blue to Mindstein's Red. While Mindstein is much perkier and has her face locked in a near-constant Slasher Smile, Screw is much calmer with a more monotone pitch in her voice and barely any expressions coming from her face.
- She's also a Blue Oni to Nurse Worse's Red, as she's more energetic and emotional than Screw is.
- Scary Stitches: Comes with the territory of being a Frankenstein monster, but unlike Nurse Worse she's truly scary.
- Stout Strength: She shares her sister's exact physique, and she's strong enough to knock Nurse out in one punch.
- Theme Naming: Her name is Hazel and her sister's name is Greta. Does that sound familiar to you? The reference extends past the names, too, with Mindstein easily fulfilling the role as the witch. Also, both women are heavyset, like they've been kept well-fed.
- Undying Loyalty: Screw obeys Mindstein's orders without question; the only thing that could stop her from doing so is putting her out of commission. However, whether Screw's loyalty is genuine or merely motivated by the threat of punishment is left up in the air.
- The Watson: Throughout the story segments of Episode 72, she kept asking Mindstein about her motivations and fascination with the Infinia, which by extension allows her to explain it to both Screw and the audience.
Metal Crafty was designed by ToxicSoul77, who also happens to be Messibelle's voice actress.
- Astonishingly Appropriate Appearance: To emulate Crafty's long, flowing lab coat, Metal has several metal plates extending downward from his back. Altogether, they resemble a bird's tail fanning out, matching his bird-like proportions and evoking the idea of a sinister bird of prey.
- Bilingual Bonus: Taken literally, "Eisen Schalu" means "Iron Clever." In other words, this robot's project name is a German rendering of "Metal Crafty."
- Evil Knockoff: Metal Crafty is Mindstein's robotic duplicate of the real Crafty, being an answer to his basis in much the same way that Screw is to Nurse.
- Expy: Metal Crafty is a blatant reference to Metal Sonic, being a robotic duplicate of their respective works' main protagonist. He draws quite a bit of inspiration from how Metal Sonic is portrayed in Sonic Heroes, how he spends Sonic Month copying the DNA of the Crafty Crew to gain their powers. Their outlooks on their respective bases is where they differ, however. Whereas Metal Sonic wants to overtake and replace Sonic, Metal wants absolutely nothing to do with Crafty, only wanting to defeat him so he never has to deal with watching his show on repeat ever again.
- Human Disguise: Throughout Sonic Month, he's perfectly capable of disguising himself as Crafty, even delivering the original's opinions on matters. It's only when the other co-hosts find the real Crafty after their episodes are done that they realize something is up...
- Intangible Man: Thanks to copying Messi, Metal is able to disperse himself into a liquid. It comes in handy when avoiding getting his head smashed in by Nurse or beating a hasty retreat, both first demonstrated in "Let's. Get. Metal..."
- The Ludovico Technique: Metal's main motivation to fight the Crafty Crew — especially Crafty himself — derives from how Mindstein forced him to watch Dr. Crafty on repeat. Having watched the show to death by this point, every little bit of it enrages him to no end; more than anything, he just wants it all to stop. Metal reveals as much to Crafty himself in "Let's. Get. Metal," and his recount of how he came to be is dripping with resentment. Notably, not once does his speech implicate Mindstein as the one at fault for his current state — Metal's sights are firmly set on Crafty and everyone he loves.Metal: "What I want is simple: I want the Doctor to suffer as much as he has made me suffer."
Crafty: "Me?! What did I do to you?!"
Metal: "You have no idea what you've done to me. And that's exactly why I must end you. You and this show! I've beared witness to every episode, every poorly timed joke, every dated reference, every frustrating plotline ad nauseum, in an endless loop from the very moment I opened my eyes. Every frame is burned into my memory banks, and the only way I can make it stop is to eliminate you, Crafty. And when I take that heart, those memories will die with you. Today."
- Power Copying: Once he's copied data from his targets, Metal is able to replicate their abilities, as shown when he turns into a liquid-like substance similar to Messibelle. It's implied that he scanned Crystelle at some point off-screen; in "Let's. Get. Metal," Crystelle can't see him through her psychic vision.
- Terminator Impersonator: Metal bears some elements of the Terminator, in the same way that Sonic Heroes' take on Metal Sonic does. He's a dangerous robot with an impeccable human disguise, has glowing red eyes, can turn into liquid thanks to copying Messibelle's data, and is out for blood.
Doctor Mindstein's army of servants.
- Distracted by the Sexy: They got distracted by Bakugo's Bishōnen appearance, which didn't end well for them.
- Everything Is An I Pod In The Future: Their mostly sleek aesthetic, white appearance, and glowing blue eyes and brains give off this vibe to their design.
- Gratuitous German: Their name is spelled "drohnes" instead of the English way of spelling without an "H."
- Not So Above It All: While you wouldn't expect them to show any emotions, one look at Bakugo made them practically swoon.
- Mecha-Mooks: Mindstein's chief footsoldiers, all made in her likeness. Their biggest strength is their sheer numbers.
- Synthetic Voice Actor: It's noticeable during the castle raid that they are voiced by a text-to-speech program
- Zerg Rush: How they took over the castle in the first place, overwhelming Pepper, Messibelle and Crystelle with their sheer numbers.
The main antagonist of "The Foreshadow Game," the Spirit of Yami Bakura (AKA Zorc) sends the Crafty Crew into the Shadow Realm. He also possesses Nurse Worse to bring her to the person who revived him: Dr. Mindstein. Before he can do so, Sasha intervenes, so Bakura decides to play a high-stakes Shadow Game with her to decide whether the Crafty Crew lives or remains trapped.
- Anime Hair: Bakura wears Nurse's hair down, and he makes it much longer and spikier.
- Arc Villain: Of "The Foreshadow Game."
- Artifact of Doom: The Millennium Ring, natch. Bakura's spirit is stored inside, and he can possess whoever holds the ring for too long.
- Badass Longcoat: He retains his black long coat from the anime.
- Broke Your Arm Punching Out Cthulhu: While he was in control for most of the duel against Sasha, almost killing her in the process, he didn't count on her helping Crafty and his friends to work together and beat him.
- Cold Ham: His voice actor mimics Ted Lewis's performance from the 4Kids dub, giving him this effect.
- Evil Costume Switch: From Nurse's regular outfit to Bakura's clothes from the Dawn of the Duel arc.
- Fat Bastard: Not the Spirit himself, but the fact that he's possessed Nurse's overweight body invokes this trope.
- Gender Bender: A male spirit inside a female body.
- The Glasses Come Off: Unlike Nurse, Bakura can see just fine without glasses.
- The Heavy: For "The Foreshadow Game," Bakura serves as the physical antagonist, who imprisons the Crafty Crew in the Shadow Realm and who Sasha challenges in order to save that crew. However, he merely serves as an extension of Mindstein's evil, and she has a greater presence across the entire show.
- Hoist by His Own Petard: Sending Crafty to the Shadow Realm proved to be a huge mistake, as Crafty used the energy of the realm to create a new monster — one fused from one of his El Shaddolls — that ended up being Bakura's undoing.
- Iconic Outfit: His striped shirt and trenchcoat are carried over from Bakura's home series.
- Killer Game Master: Naturally, his method of battling Sasha is with a game of Duel Monsters.
- Marionette Master: His entire deck is filled with Shaddoll archetype cards.
- Sadist: He loved making Sasha suffer during their duel.
- Tsurime Eyes: His eyes are much sharper and angular than Nurse's.
- Vile Villain, Saccharine Show: By the time he shows up in "The Foreshadow Game," Bakura presents an unprecedentedly clear and present danger for the Crafty crew. Indeed, he's just as evil here as in his origin show.
- Villainous Breakdown: While normally calm and collected, he started losing his temper once the duel quickly shifted in Crafty's favor.
- Voices Are Mental: When he's in control, the other characters notice the change in voice.
During Cartoon Month, Mindstein reincarnates Bill Cipher and forces him to scout Crafty's mind for important secrets. If he finds what Mindstein is after, he is allowed to go free. However, he finds himself unable to infiltrate Crafty's head, so he instead takes interest in Nurse's.
- Actor Allusion: Just before Bill burns into oblivion in "Titans! Reboot," he quickly takes on the likenesses of other characters Alex Rochon has played, with their details squished down into Bill's triangular shape. Those characters are Hades, Sans, and the Boogieman; Bill cycles through each of their appearances within a few seconds.
- Adaptational Wimp: Bill spends much of his screen time at the mercy of Infinium artifacts. Mindstein is able to take charge of him with the Infinium Flute, and Sasha ultimately kills him with her Infinium Sword. Thus, he doesn't get to use his powers much beyond infiltrating Nurse's mind.
- Back from the Dead: Since Dr. Crafty takes place after Gravity Falls' events, Bill is dead... at first. Mindstein revives him in "Charablanca" with the Infinium torch. Bill's revival is notable for presenting the first explicit use of any Infinium Relic onscreen.
- Deader Than Dead: In "Titans! Reboot," Sasha slays Bill with her Infinium Sword, a weapon designed to kill gods. She outlines in no uncertain terms that the weapon will render him irreversibly dead. Nothing — not even the Infinium Flute Mindstein used — will be able to revive him again. True to Sasha's word, every physical trace of Bill vanishes after his death; he's merely a memory now.
- Small Role, Big Impact: Unlike Bakura, Bill Cipher doesn't receive much screen time. He makes the most of little he does have, however. His actions offer insight into Nurse's backstory, very nearly curing her Trauma-Induced Amnesia in the process. What's more, his showdown with Sasha in "Titans! Reboot" establishes the social hierarchy of the Infinia among deities across the multiverse. He also paves the way for Mindstein's in-person introduction to the Crew in "Magic Kingdom Mania," which leads into an action-packed Season Finale month that reveals even more information about Dr. Crafty's world.
- Wolf Whistle: In "Socializing is Arcane," Bill Cipher whistles upon finding a specific memory of Nurse Worse dressed as Sandy from "Grease Frightening."