Characters in Ninja Turtles: The Next Mutation.
- The Leader: As always, he's the one who's in charge of the Ninja Turtles.
- Sibling Rivalry: Some things never change. While the Turtles are not blood related in this continuity, he still gets into squabbles with Raphael from time to time.
- Weapon of Choice: A single katana sword is his weapon.
- Foil: He acts as one to Venus, focusing on solving problems the scientific way while Venus chooses to rely on the mystic arts. It understandably results in them getting into tiffs on occasion.
- Gadgeteer Genius: Like most incarnations, he uses his intellect to fashion devices to help him and the other Turtles fight their enemies.
- The Smart Guy: As always, he's the brainiest of the Ninja Turtles.
- Weapon of Choice: He fights with a chrome bo staff.
- Humans Are Bastards: Of all the Turtles, he's the one most disdainful toward humans.
- Jerk with a Heart of Gold: Like most versions of Raph, this version is a complete grouch, but is still on the side of good and willing to help others and stop bad people.
- Sibling Rivalry: The Turtles may not be actual siblings in this continuity, but he and Leo still butt heads on occasion.
- Weapon of Choice: He fights with a pair of sai.
- Adaptational Jerkass: This incarnation of Michelangelo is a bit ruder than he's usually depicted, most notably due to sometimes making lecherous comments toward Venus.
- Manchild: Like many versions of Michelangelo, he's a bit childish, at one point slacking his duties so he can play a video game.
- Weapon of Choice: Instead of nunchucks, he fights using tonfa.
Venus de Milo
- Action Girl: Took out the Shredder with her magic and can keep up with the others in terms of fighting.
- Blunt Metaphors Trauma: Well, she is new to American culture, so it's understandable that she constantly gets figures of speech and sayings confused.
- The Chick: Certainly the most girly and in tune with her feeling of the group.
- Fifth Turtle/The Smurfette Principle: Introduced as the team's newest turtle who happens to be the team's only female member.
- Funny Foreigner: She's Chinese and she never did manage to learn that the Turtles lived in the "sewer" and not in the "toilet."
- Kung-Fu Wizard: She is a shinobi who inherited some mystical 'chi magic' abilities.
- Lady of War: Venus is a proper lady who kicks all sorts of shell.
- Literal-Minded: Her usual reaction when it comes to expressions is to assume that the speaker meant their phrase literally.
- Non-Mammal Mammaries: In spite of being a mutant reptile, she appears to have breasts underneath her plastron.
- Odd Name Out: She's the only one to share a name with an artwork. Sort of justified since the closest we would get for a female name is Artemisia Gentileschi.
- Only Known by Their Nickname: Her real name is Mei Pieh Chi.
- Organic Bra: Her breasts are covered by her plastron.
- Retcon: During her introduction, Venus was somewhat clumsily inserted into the Turtles' already-established origin by explaining that there was a fifth turtle that Splinter missed when he first found the turtles.
- Weapon of Choice: Notable for not having one, outside of occasional mystic orbs. The toys gave her Battle Fans, but these were never seen in the show proper.
- Black Best Friend: He is friends with a black man named Andre who is blind.
- Rat Folk: Like many incarnations, he's a rat mutated into humanoid form.
- The Farmer and the Viper: In "Enemy of My Enemy", Splinter finds him and takes him in after he discovers he's become a derelict after his defeat in the series premiere. Against the Turtles' wishes, he tries to rehabilitate him. This doesn't change anything about Oroku Saki's hatred of the Turtles and the episode ends with him presumably planning his next attempt at defeating the Turtles.
- Good Scars, Evil Scars: As in the 1990 film and its sequel, this incarnation of the Shredder has a scar on his face underneath the helmet he wears.
- HeelFace Brainwashing: Venus essentially puts the Shredder out of action by using magic to make him realize the fiend he's become. It doesn't stick.
- Starter Villain: He is the first antagonist that the original four Turtles and Venus confront in this series.
- Surrounded by Idiots: His first scene has him yell at a pair of Foot Ninjas for losing in battle and express incredulous ire at the excuse they give for their failure.
- Big Bad: He's the main villain of this series, anyway, after the Turtles finally defeated the Shredder while also unintentionally releasing the Rank.
- The Corrupter: He was once the only bad member of the Rank, until he turned the rest of them against mankind.
- Evil Overlord: The ill-tempered dictator that leads the Rank and wants to reclaim the Earth for the dragons.
- Power-Up Food: The Dragon Lord wants to eat the turtles, so he can have the "magic" that made them what they are, believing it will make him stronger.
- Non-Mammalian Hair: Seen when he's not wearing his helmet.
- Reptiles Are Abhorrent: Easily the most evil reptile in the show.
- Sealed Evil in a Can: The Rank were imprisoned in an enchanted mirror before breaking free in the Five-Episode Pilot.
- Suspiciously Similar Substitute: He has a lot in common with the Shredder. Even his armor has some similarities.
- Co-Dragons: Shared the role with the Rank Lieutenant who leads Dragon Lord's army. Made room for Dr. Quease after he joined the Rank.
- Dirty Coward/Non-Action Guy: He's a simpering wimp with no fighting abilities whatsoever.
- Evil Brit: He speaks with a Yorkshire accent when he gains his new powers in "King Wick".
- Evil Laugh: A wicked cackle done when he's actively doing evil or he thinks he has the upper hand.
- Smug Snake: He sucks up to the Dragon Lord but would have no problem usurping him if given the chance.
- Squishy Wizard: The go-to dragon if Dragon Lord needs a potion. He's a low threat when it comes to battle.
- The Starscream: Wick became this to the Dragonlord in the episode "King Wick" after accidentally drinking a potion that gives him new powers. He uses his new powers to steal Dragonlord's powers and become the new leader of the Rank, but eventually is tricked into losing his powers.
- Co-Dragons: Shared the role with Wick and later Dr. Quease after he joined the Rank.
- Mauve Shirt/Satellite Character: Doesn't have much characterization or backstory in his own right. Aside from his purple veil, his only known for being an underling for the Dragon Lord in the Rank.
- Mook Lieutenant: He differs from the other dragon soldiers in that he wears a magenta veil over his mouth in contrast to the others' purple veils.
Dr. Cornelius Quease
- Broken Pedestal: Donatello used to admire him as a genius, but became disillusioned when he realized that Quease had become affiliated with the Rank.
- Co-Dragons: With Wick and the Rank Lt. once he was brought in by the Dragon Lord.
- Even Evil Has Standards: Dr. Quease tries to invoke this by pointing out his method of destroying his nearly robotic clones of the Turtles is painless. Naturally the Turtles disagree.
- Eye Scream: Though it's played up. He TORE ONE OF HIS EYES OUT FOR A SCOUTING ROBOT. He later has to destroy it to get Venus' DNA. This just seems to merely annoy him since he just clones a new one.
- Mad Scientist: This guy had little issue on experimenting on live subjects, finding ways to feed the turtles to the Dragon Lord and ripping out his own eye (see Eye Scream above).
- Morally Ambiguous Doctorate: An actual doctor, but no less insane.
- Suspiciously Similar Substitute: Dr. Quease is similar to Baxter Stockman, namely in that both are mad scientists.
- Bad People Abuse Animals: "Going Ape" has him admit that he enjoys harming baby seals.
- Bunny-Ears Lawyer: Despite being acknowledged as stupid, he is a very experienced tracker and its mentioned he's really only having trouble with the turtles because they're smart enough to fight back.
- Butt-Monkey: He doesn't fair much better than Elmer Fudd when hunting the Turtles.
- Evil Is Hammy: He's an unscrupulous hunter who often chews the scenery.
- Evil Poacher: He hunts and captures endangered animals for profit.
- I Call It "Vera": Has many weapons with girl's names. The Turtles even lampshade it, with Leonardo asking what kind of weirdo would name his weapons and Donatello deducing that he has an infantile attachment toward inanimate objects.
- The Straight and Arrow Path: His crossbow, Marylou, being his Weapon of Choice.
- Taxidermy Is Creepy: In a couple episodes, he has a stuffed monkey on a swing. Played for laughs, though.
- Vampire Hunter: Simon used to do this, it came in handy when he had to deal with Vam-Mi. Could also be a Shout-Out to Castlevania due to him being a Vampire Hunter named Simon.
- Badass in a Nice Suit: Always dressed in a lime green suit with a black shirt and red tie.
- Bigfoot, Sasquatch and Yeti: In the show, Silver says he's the last of the Himalayan Yeti alive.
- Damn, It Feels Good to Be a Gangster!: Implied that he started feeling good when it distracted him from being the last of his kind. Now he enjoys stealing money.
- Evil Is Hammy/Evil Laugh: Silver certainly has a flair for bravado.
- From Nobody to Nightmare: Silver: I clawed my way from the Bigfoot ghettos of the Himilayas to the Big Apple.I'm the only one of my kind left in the world and no mere turtle is going to stop me!
- Greed: All of his schemes revolve around stealing valuables.
- Last of His Kind: He claims to be the last living Himalayan Yeti, which he uses as a crutch for committing his crimes.
- Sadistic Choice: In his first appearance, he gave the other four turtles the choice of either going after him as he made his escape or rescuing Venus from being blown to bits by the bomb she was locked with in a bank vault. Donatello rescued her in the nick of time.
- Surrounded by Idiots: His underlings are incredibly stupid, much to his annoyance.
- Trademark Favorite Food: He likes bananas.
- Arc Villain: She was the main villain in the multi-part episode "Unchain My Heart".
- Beat Still, My Heart: She was sealed away for 17 years without her heart and tried to restore it until she crumbled to dust.
- Co-Dragons: She is assisted by a pair of vampires that look like children, Bing and Chi-Chu. Bing resembles a boy and has a rather deep voice and Chi-Chu resembles a girl.
- Drowning My Sorrows: Apparently, 12 bags of ice cold plasma blood can get her drunk.
- Killed Off for Real: Notable for being the only antagonist to be permanently defeated, as she turned to dust when the Turtles prevented her from getting her heart back.
- Sealed Evil in a Can: She was locked inside her coffin for 17 years without her heart.