The main protagonist. He's lost his memories and got a Caiman Lizard head. He seeks to regain both his face and memories by hunting down Magic-Users, whom he believes to be responsible for his state. His M.O.? Find em and stick their heads in his mouth, where they meet a strange man later revealed to be a duplicate of Risu who, so far, has said nothing but,"You're not the one." Yes, this man is living inside his mouth. Then he pulls em out, and when they tell him that they are not the one, he kills them. Horribly.
Anti-Hero: Type III, though he's rather nice with those he considers his friends. It's mostly because he lives in a Crapsack World.
Anti-Magic: He's immune to Magic, which makes him very dangerous to the Magic-Users, who often are too reliant on their powers. Unfortunately, this only makes him immune from being transformed or affected directly by smoke. Magical items can still hurt him, as seen when he fights En.
Kaiman's friend. She follows him into his quest of regaining his memories and human face. She runs the Hungry Bug restaurant and makes the best gyozas of the city. She's a Magic-User who came to Hole and vowed to never use her Magic again. She has the ability to manipulate time, and gets hunted down by En because of it.
Our Demons Are Different: She's becoming a devil accidentally (unfortunately those parts were skipped by the translators, but it seems to be Asu helping her to control her powers), mainly because unlike most magic-users she's used to not using her powers.
Go Karting with Bowser: Whenever he interacts with Shin. The two of them are downright friendly and even end up helping each other.
Happily Married: Sort of. He hadn't seen her for years prior to the story, though they are still very fond of each other.
Haunted House: Lives in one due to magic users' smoke filling the place.
Mad Scientist: He has a lab filled with the corpses of magic users and a door that he made out of magic user body parts. He also operated on Shin to help him use magic. For no apparent reason. See For Science! above.
Older than They Look: He's actually in his sixties but looks like a teenager. His explanation is that he was a test subject for a magic user.
Only Known by His Nickname: His real name is Haze, though it seems only Haru knows this. In addition "Kasukabe" is actually his wife's real name.
Fluffy Tamer: Decided a giant, man-eating cockroach would be a handy pet. The two have been inseparable ever since.
A cockroach changed by the residual magic in the Hole to become human-sized. Wears sneakers and proclaims, "Shocking!"
A Magic User and gang leader of a sort. His "Family" engages in various enterprises, obviously quite successful as he lives in what amounts to a small town. He has great influence in the Magic Users' world and has connections to Devils. If the origin story in his movie is to be believed, his magic was strong enough as a child to turn both of his parents into mushrooms. Afterwards, he was abducted by weak Magic Users who held him prisoner and sold his smoke on the black market. Eventually, he was discarded and ended up in hell, where he apparently impressed the Devils enough to escape. He returned to the place where he had been imprisoned and freed the others, starting his "Family." Somewhere along the line he sent his men to fight the Cross-Eyes, and many of them died. After that, En decided that his destiny was to take down the boss of the Cross-Eyes.
Anti-Villain (Type I): Orders to kill his enemies around the town and threatens to turn his subordinates in mushrooms if they double-cross him. In the other hand, he does care for his subordinates and despises injustice despite the whole Yakuza-like behavior.
Back from the Dead: If his family can get his devil-tumor and Kikurage to his reconstituted body, currently (I believe) in the morgue at Hole's hospital.
Large Ham: He makes a movie about himself, with an overly dramatic origin story and description of the Cross-Eyes' boss as his fated enemy. And in a visual example, his estate has statues of himself everywhere.
Person of Mass Destruction: Well, technically he doesn't destroy things so much as turn them into mushrooms. Entire towns, if you push him too far.
A Magic-User who works for En as a "Cleaner." He wears a heart-shaped mask. Underneath, he has an ordinary appearance. He likes to eat and engages in casual conversation with Noi. On the job, he becomes bloodthirsty and ruthless, ripping apart anyone in his way. His magic involves vivisecting people, who remain alive no matter how much he tears them up. He comes from the Hole, where, due to being half-Magic User, he was attacked by the militia from the Hole. After cutting off his arms in an effort to use magic, he gets Dr. Kasukabe to help him. He uses his newfound power to massacre the militia and heads to the Magic Users' world. There he meets and fights Noi, and gets a job working for En.
Sempai Kohai: He's Noi's Sempai, though she has been with En longer. Probably because he's been En's cleaner longer than Noi.
Ship Tease: Not so much on Shin's side, but he's incredibly modest about Noi, becoming embarrassed whenever he sees her under-dressed, and usually responding with a red face when she does her own side of the Ship Tease. Almost done when he implants the charms that could bring someone back from fatal wounds, but he pulls back the last minute.
En's cousin and Cleaner, Noi works alongside her partner Shin, wearing a sort of wrestler's mask. Shown to be albino in colored pictures, Noi is almost always friendly and laughing. However, she can't take people being stronger than her, and she worries a lot about her partner. Her magic is a Healing Factor, allowing her to rebuild anyone from almost anything unless they're dead. When she was younger, she was trying to become a devil, and had gone with Shin to face an incredibly tough opponent three days before the Blue Night came. The final phrase of becoming a devil involves not using your magic until the Blue Night; unfortunately, moments before the hit had ended, Shin was fatally wounded, having jumped in to save Noi from a killing blow. Noi ruined her contract to heal Shin, but she never held a grudge against it - when that Blue Night came, they signed a contract to become partners and have been that way ever since.
Combat Stilettos: Averted, she always wears sensible tennis shoes and the one time she wore heels she could barely walk.
Friendly Enemy: When she meets Nikaido, she is pretty impressed by Nikaido's strength, and declares that the two of them should be friends. Later, when Kasukabe, Shin's close friend, starts to stay with them with several other Hole residents, Noi gets along with them just as well as Shin does.
It's also why Noi is highly valued in En's Family. Even though she can survive almost anything, she's often pestered into staying behind in a safe location when the going gets tough, much to her chagrin.
Ship Tease: With Shin, to an unbelievable amount. On at least two occasions, Noi has kissed Shin to fully heal him even though just hovering over his open mouth would've work just as well, she's teased him onscreen once by sleeping on his bed (which lead to a regular member thinking he was interrupting something, and from how Noi worries about Shin, even in an omake becoming worried that he wanted to return to the Hole, it would feel like they're in a relationship or already married. Not helped by them sharing an apartment (though not rooms), and even Shin returning some feelings too.
Unskilled, but Strong: Shin criticizes her for relying too much on her healing magic. He notes that she doesn't even try dodging attacks anymore, which comes back to bite her in the ass when going up against the Cross-Eyes for the first time.
A weak Magic User who works for En. Despite being something of an errand boy, he ends up getting involved fairly regularly with the higher up members of the family, most likely because of his connection to Kaiman. Who, incidentally, killed his partner Matsumura.
Fear Is the Appropriate Response: Compared to the others of En's Family, Fujita shows what most of us would usually do in the situation. It's exactly why he's picked to go undercover and invisible to find out information about the Cross-Eyes and their boss; everyone else, especially the best fighters Shin and Noi, would use the opportunity to attack and would likely die.
I Just Want to Be Badass: Having very weak magic and being bullied because of it, Fujita asks Shin and Noi to teach him to be stronger, which they turned him down immediately.
Oh Crap: When he's forced to work with one of the Cross-eyes to escape the wrecked shopping center and the Cross-Eye realizes Fujita's hiding something — the tiny devil-shaped tumor that can help resurrect En.
A young female Magic User who loses her memory and her sanity after getting her face ripped off by Kaiman. She gets "rescued" by Fujita, who wants her for her expertise in reptilian transformations, thinking she might have a connection to whoever cursed Kaiman.
Nice Job Breaking It, Hero: Had Fujita arrived a moment later the whole incident with her face would not have happened (Kaiman would have spat her out to ask what the man inside his throat said to her).
Replacement Gold Fish: When she ran away from home her parents paid a magic-user to make a clone; unfortunately the clone was very unstable and scared them out of their house.
A gang which sells black powder, a substance that dramatically increases the amount of smoke a Magic User can produce. They set themselves up as the heroes of the weak Magic Users, who are treated little better than humans.
The mysterious boss of the Cross-Eyes. He was originally a human from Hole, who asked Kasukabe to make him into a Magic User. After he met Dokuga and his friends, about to be exiled by some Magic Users to the Hole, he killed the Magic Users, took them along with him through the door into the Magic Users' world, and formed the Cross-Eyes. He was attacked by Risu's Curse power after killing Risu and ended up in the Hole as Kaiman. Due to Mega Manning and his own strength, he is an extremely formidable fighter.Also rather insane.
Bad Boss: Kills Natsuki to get her defensive magic. Also kills Risu for a similar reason.
Body Horror: C'mon, he can sprout multiple heads, which just hang there from their own spinal cords. He also puts the devils from the heads of Magic Users into his own head.
Extra Life: Had nine spare heads, but most of them are gone.
From Nobody to Nightmare: He starts out as a kid in the Hole who wants to be a Magic User. He ends up (briefly) ruling the Magic Users' world.
Humanoid Abomination: He removes his own heads when he switches personalities and his mere presence makes Magic Users see their surroundings distort. Fujita sees the headless/shoulderless person from Kaiman's dreams when Kai is near.
Human Sacrifice: What he called the mass of corpses and devil-tumors he brought with him to refuse lake in Hole. Possibly what he's going to use to appeal to the devils to become one himself.
I Just Want To Be Abnormal: As a human he cannot become a magic-user and and becoming a devil is impossible but he seems be succeeding.
Pet the Dog: Saving Dokuga and his friends, and giving Ton one of his hamburgers. Though it just makes what he does to Natsuki worse.
A member of the Cross-Eyes who went into hiding after the boss vanished. He is extremely skilled in hand to hand combat and can kill Magic Users with ease. Solemn and serious, he is also capable of wreaking havoc when needed. He is devoted to his small group of friends, who, like him, live in poverty to make sure that En does not find them.
Almighty Janitor: The second-in-command of the Cross-Eyes, an organization that even En takes seriously, and also a termite extractor, bath attendant, and whatever else he can land as a job.
Poisonous Person: His saliva is toxic. Which is why he eats, bathes and brushes his teeth separately from his comrades. Of course, if he wants to poison the punch at a party...
Played for Laughs when he uses this to exterminate termites in order to earn some money.
The Stoic: He actually can't laugh, or he'll end up killing his friends.
A former member of the Cross-Eyes, who is searching for his killer. He is the man in Kaiman's mouth, having cursed him after the Cross-Eyes' Boss (a.k.a. Kaiman's Split Personality) killed him. Shin and Noi find and restore his head, and he eventually gets his normal human body back. He wields Curse magic.
Death Is Cheap: In the beginning of story, he was already dead, being killed by Kai. He was revived by Kikurage.
I Just Want to Be Normal: He just wants to be a Magic User, and goes to a magic academy to try and develop any latent abilities he might have.
A cheerful girl who joined the Cross-Eyes because she saw them as heroes, sticking up for the weak and powerless. However, she is disillusioned with her boss when he attempts to con said weak and powerless. She follows Kaiman, thinking him to be a real Cross-Eye and eventually joins Dokuga's gang. Her magic is defensive, manifesting itself as a large, impenetrable blob around her body.
Took a Level in Badass: After getting her arm cut off and discovering her magic. She even fights off Risu's Curse power, which Dokuga and the others were unable to do.
A Devil who knows Nikaido and helps her out on several occasions. A former Magic User named Kawajiri.
Body Horror: He gets butchered (as in gets his horn cut off and then has his skin and several inches of flesh taken away to be sold) and turned back into a Magic User. A bloody, nearly dead Magic User.
Childhood Friend: Nikaido's. Though, since she changed the past with her magic, he doesn't know it.
Creepy Cool Crosses: After the above body-horror he has a chunk of flesh missing near the base of his spine in the shape of an upside-down cross.
Eye Scream: When he tries to use his clairvoyance to find a way out of Hole Central Department Store after it's been taken over by demon-Kai/Aikawa "something bad" gets in his eyes, blocking his powers and blinding him.