LaddRusso from Baccano! is an example of this trope in the vein of Quentin Tarantino. When he hears gunshots he gets giddy to the point of SKIPPING TOWARD THE ACTION. Blood is something to celebrate and perhaps even dance in. This should be horrific except Ladd's hammy approach to it all makes him one of the comic relief characters.
And then there's Claire, Nice, and Dallas. This show is MOSTLY an example of this trope.
In the anime 3×3 Eyes, the male protagonist Yakumo Fujii was made more or less immortal and is constantly dying or being killed. Good Thing You Can Heal, Yakumo. The more he dies, the funnier it gets.
At one point, Kaede gets slammed into a wall after getting blindsided by Ku Fei during a training exercise, prompting Anya to wonder if she was still alive. She then emerges from the rubble unharmed... except for a large fountain of blood from the forehead, which she ignores.
This is one of Izumi Curtis's shticks in Fullmetal Alchemist. She's got nasty internal injuries, so often, in the middle of a Bad Ass speech or right after beating up her students, she'll puke blood and have to be comforted by her husband. It's used dramatically too.
Soul Eater often plays characters getting serious injuries (and usually shooting blood all over the place) for comedy. It helps that they're generally perfectly okay a minute later.
Some fights go between comedy and serious; Stein fighting Crona, for example, as it starts with the child getting stabbed through the chest, clearly and rather abruptly.
Saitama Chainsaw Shoujo: The Axe Crazy protagonist Fumio's reaction to getting sprayed in the face after taking down someone standing between her and her target, the ex-boyfriend Takumi, could be taken as innuendo for a different kind of fluid.
Fumio: "Ahh... But I had really wanted Takumi's blood to be the first on me."
In One Piece, Sanji's many instances of Nose Bleed are, without exception, played for laughs. Even when the blood loss almost kills him.
In Yuru Yuri, Chitose's nosebleeds can end up here. Especially in episode 13 of the first series.
Jinrui Wa Suitai Shimashita has the suicidal robot bread (technically carrot juice, not blood). Whether you think this is funny or horrifying is a fairly good indication of if you'll like the show.
Sin City often ventures into this camp, whether it's Marv grinding someone's face into the pavement as he drives, Jack Rafferty gradually being hacked up, or Shlubb and Klump being brutalized. The violence goes so over the top that it's just fun to watch. Sometimes.
This is the main point of the Sinister Spider Man mini-series from Dark Reign. The title character is secretly Venom... who eats people. For fun. At one point, Venom half-digests a bad guy.
In Finder, there's a memorable scene where Jaeger, the hero, is suffering from auto-immune problems due to his overactive Healing Factor not having had enough to do for a while. He ends up secretly cutting himself in his girlfriend's bathroom, and gets carried away, leaving himself sliced to ribbons and the bathroom soaked in blood. At this point the girlfriend comes home unexpectedly, and he frantically and hilariously tries to wipe up the mess with towels, before panicking and jumping out of the window. The girlfriend muses sadly that she never had anybody kill himself and run away from her before.
In their movie, Monty Pythons The Meaning Of Life, two men set about harvesting organs from a donor... A perfectly, healthy, conscious man who is quite unhappy about the whole affair, to say the least. Five minutes of horrific screaming and spurting blood manages to cross the line so many times, we lost count. And from his point of view, with his hands occasionally coming into shot to grab back at the organs as they are ripped away.
Michael Palin and Terry Gilliam also made Jabberwocky, set in the Middle Ages, with many examples of this trope. Most memorable was the king and princess getting repeatedly splattered with blood while observing a jousting tournament from the royal box and calmly discussing the outcome with a royal advisor.
UHF and the in-film Home Improvement TV show. Is my face red.... Of course, in the end, It's Just a Flesh Wound.
This is the entire point of the Evil Dead sequels. Especially the second movie.
Speaking of Robert Rodriguez, he indulged in this on the Sin City film, when the Neo-Nazi enthusiast of a torture specialist's work manages to get speared through by one of Deadly Little Miho's arrows, ask plaintively for medical assistance as the baddies read the attached note and make plans, then sigh in disgust as he's deserted and promptly shot through the head with Miho's follow-up shot.
Repo! The Genetic Opera has 'Mark It Up', in which one half of the comic relief duo brutally stabs one of the women in his employ in the stomach for a minor offence. Throughout the scene, she's thrashing around, bleeding, choking, and dying in agony. Meanwhile, her murderer and his brother bicker in song over which of them will inherit their dad's company, throw human organs at scantily clad nurses, and flirt with other women, who are apparently neither surprised nor concerned that one of their co-workers is dying at their feet. In fact, she goes completely ignored. This is widely considered to be the funniest scene in the movie.
Which, according to IMDB is the bloodiest movie of all time, one scene having fake blood pumped at 5 gallons per second for a total of 300 liters (two different listings). In a Crowning Moment of Awesome, the protagonist slings a lawnmower over his shoulder with a rope and (almost literally) wades into a room full of zombies...
Made only funnier by the reaction shots from the headless forklift driver.
In the commentary for Sleepy Hollow, Tim Burton admitted that he attempted to find as many opportunities as possible to have Johnny Depp's character sprayed in the face with blood.
There's a scene in the otherwise mediocre and forgettable werewolf movie Cursed that has a bitchy cheerleader trying to crawl away from the site of her crashed car/werewolf attack. When she notices that she's not getting very far, she looks down at her legs to discover... she's been ripped in half.
The Cutaway Gag in the tv-movie Dark Night Of The Scarecrow when the first revenge victim falls into a running woodchipper and the scene abruptly cuts to a closeup of a blob of strawberry jam landing on a plate.
District 9 is a totally serious film, albeit laced with a dark streak of black humour. This does not make the effects of alien weaponry on people any less hilarious. Or AWESOME.
When Machete rappels down the side of a building.... with a mook's intestines.
The first part of A Serious Man involves a faux folk tale of a man who invites another man in... only to find that his wife had heard that the man he was supposed to be had died. Believing him to be a dybbuk, she stabs him. The humor comes from the man treating this as a mere social slight as blood comes out of his chest. Knowing when he isn't wanted, he gets up, and leaves into the night.
Galaxy Quest has a rather graphic transporter failure in which an alien creature is beamed aboard the spaceship with most of its parts in the wrong places. It survives for a little while before exploding, which does nothing to reassure a crew member that the transporter will work on him.
Scary Movie 5 features a chicken getting it's head ripped off; the amount of blood that shoots out allows the housekeeper to paint a crucifix on the wall while the two main characters chat with each other, oblivious to the carnage behind them.
Live Action TV
Scrubs: In the season three episode "My Tormented Mentor," when Cox and Kelso fight over Dr Miller, they are shown tearing off her arms and beating one another with them. She looks unimpressed as blood pumps from the stumps.
Friends: in the season five episode "The One With All The Thanksgivings," Phoebe has two past life flashbacks involving being a nurse in a war. In both, her left arm is blown off, and we see copious blood pump from the wound as she shouts for more gauze.
An old Saturday Night Live sketch has a Julia Child parody "cut the dickens out of [her] thumb," and subsequently bleed all over the set while trying to continue as though nothing had happened. As with most classic SNL, very funny.
Breaking Bad did it in particularly graphic fashion (being a cable show and all). In season 1, Jesse and Walt need to dispose of a body; Walt tells Jesse to get hydrofluoric acid and a specific kind of plastic tub. Jesse doesn't see the reason for the second part and simply puts the body and the acid in an ordinary bathtub. As it turns out, the plastic tub was necessary because the hydrofluoric acid would dissolve anything else... including the bathtub. And the floor. When what's left of the body falls through the ceiling, what was once a human corpse has been reduced to a chunky liquid form. The camera lingers on the gory mess long enough that there is some Squick factor, but I defy you to watch the scene and not laugh.
In the next season, we get to witness a junkie's head getting crushed by an ATM.
Mad Men also does it rather graphically in "Guy Walks Into an Advertising Agency," when the person who is supposed to replace Layne Pryce gets his foot run over by a riding lawnmower, splattering several bystanders with blood.
A later season skit has John Madden do this to himself while assembling a birdhouse using ordinary handheld power tools.
Victorious: In "Tori Gets Stuck" Robbie picks up a bag of blood Tori just donated only to drop it causing it to explode and splatter the both of them. In fact, this very scene is the page picture for the show's copiously filled Radar page.
Matt: It's called "Quentin Tatantino's Hallmark Movie, Turkey Won't Die." It's about a mortally wounded bird that will not die, even as it's being served. Did he find the premise realistic?... If geysers of blood are gushing out, then I get the Tarantino joke, and it's funny. If it's just a realistic amount of blood, then it's... extremely disturbing...
Bobby on Supernatural throws an okami into a wood chipper, and the Ludicrous Gibs mostly land on the lady he was saving from the okami.
On the second-season 2 Broke Girls episode "And the Egg Special," Caroline changes her mind about donating her eggs to raise money for the cupcake shop and pulls out her IV, leading to blood spraying all over the clinic walls (and an Ironic Echo of a scene earlier in the episode).
The song "Schlaflied" (Lullaby) by German band Die Ärzte is all about this. While it's entirely in the style of a nursery rhyme, the lyrics are constantly getting gorier and more bizarre.
Myth and Legend
In Norse Mythology, part of the creation story can be viewed this way, making this Older Than They Think. When the frost giant Ymir is murdered for no particular reason, he bleeds so much a race of giants drown in his blood. Except for two, because they had a boat.
Then Odin and his brothers used the flesh and blood of Ymir to make Midgard. They made the sky from his skull. The blood? We call that the "ocean".
The Spoils seems to aim for this, often including sardonic one-liners as flavor text on its more gruesome cards.
The entire purpose of the Bloody Mess trait/perk in the Fallout series, and a good amount of combat besides. In Fallout 3, even without the perk, a grenades or gunshots can blow limbs or faces off, and the first time a headshot blows a person's entire head off or away (It seems to work like this: limbs are torn off by a fatal attack being delivered to that area on the target, and they explode if said area was crippled. With the Bloody Mess perk, dismemberment happens just because.), it's rather grotesque. After a few times seeing eyeballs rain down, though it quickly launches into the humor category.
Especially when you have done this by launching a teddy bear at them.
A personal favourite is Bloody Mess + Dinner Plate = the victim's limbs and head exploding in different directions.
In Fallout 3 Moira will eventually give you a chemical that was supposed to drive off molerats. Instead their heads explode.
The Fallout 1/2 animations were even better. Blowing someone up with a shotgun would shoot a gigantic hole in the target that disintegrates the arm and turns the torso into a crescent-shaped mess. It really has to be seen to be believed.
The sheer, unbelievable quantity of gore in Rise of the Triad with the Engine Killing Gibs cheat activated qualifies, especially with severed hands wagging their middle fingers flying across the screen.
The Mortal Kombat series in general tended in this direction. The blood was so copious from every single punch that a few seconds would be expected to exsanguinate the player, and fatalities were often so over the top it became hilarious. Self parodied with the Babalities and Animalities.
Dwarf Fortress Adventure Mode: The game where you can beat dragons to death with a sock or go on a genocidal rampage with a severed elf leg. Fortress Mode lets you drop goblins onto walls of adamantine buzzsaws, splattering blood for dozens of feet around. You will start grinning after seeing a few would-be invaders reduced to goblin salsa.
Toady's developer log is great resource for this:
"During the test (a 20 sword free-for-all), a guy got stabbed in the lower body twice, his guts popped out, and then a third guy came up and severed his exposed guts, so that all seems to be working."
"The dwarf Zach had selected didn't have any surgical experience. As I was watching, blood splattered on the walls and floor, and another dwarf ran over to diagnose the patient again, while the dabbling surgeon moved between repairing the compound fracture and trying to stop bleeding from malpractice. Eventually it was time to suture up the wound, and the dabbling surgeon did this... then again... then again... our poor patient had four sutures in his left wrist before I got the bug figured out."
This can happen with a little effort (or luck) in a few of the Jedi Knight games. By activating the dismemberment cheat, enemies who have their hands cut off by your lightsaber will fall to their knees and grab their severed wrist in agony for a few seconds, before falling down dead. If you quickly severe their head during that animation, the now-headless body will continue lamenting the loss of its hand.
There was a tiny little game called Jump'n'Bump, featuring very cute little rabbits that the players controlled. Very cute, until you realised the point of the game was to jump on top of the other rabbits, resulting in an explosion of bloody rabbit parts.
Dead Rising features a few ways, though most notable is The Excavator. Impale a zombie with it, and let the laughs ensue as you walk around, spinning zombie corpse beating down other zombies with its flailing limbs.
Team Fortress 2 often takes this route, most notably when your character meets an explosive death and the game enthusiastically points out where your scattered bits are in the subsequent screenshot. There's also an unlockable item called "The Bombonicon" that causes your player to "explode spectacularly upon death", regardless of how they're killed.
Several of the "Meet the Team" sketches also wander into this trope's territory, such as "Meet the Sandvich," from which the first of the two page quotes was taken. What makes the deaths even funnier is that the characters all look like they're from a Pixar movie. Subverted with "Meet the Pyro" where the violence becomes a lot more disturbing when contrasted with the Sugar Bowl sequences (however, some thought Meet the Pyro was terrifying, while others thought it was one of the funniest animated shorts ever made).
The whole point of MadWorld is to kill enemies in the most creative, elaborate ways possible to score more points. The gore is so over the top that things that would normally be morbid just run right back into funny. The executions of the bosses, often with their own weapons, are particularly ridiculous.
Much like MadWorld, Bulletstorm combines this with The Joys Of Torturing Mooks. You get points for turning enemies into human fireworks, feeding them to local wildlife, bowling them over with cannonballs, kicking them into spikes, live wires, off cliffs... If you're brutal enough, the other mooks stop to gawk. It's a rather samey FPS, if you play it like an actual shooter and not a Murder Simulator.
In Psychonauts, you can stomp lungfish into a bloody pulp in Lungfishopolis. And it's awesome.
This is the entire concept of the iOS game Fun Run.
Surgeon Simulator 2013. The whole point of the game is to perform surgeries using a combination of Waggle and Wreaking Havok, with no regard for actual procedure, biology, or cleanliness. As such, you'll be happily breaking apart a person's ribcage with a hammer before tearing out their internal organs with your bare hands and casually tossing them aside to make room for the replacement parts.
Zoidberg: (*shocked tone*) Blood?! I mean, (*enthusiastic tone*) blood!
Fry: Put it back in me!
And later: Leela: (*hopping around the operating table with her upper torso*) All you had to do was stop cutting my spine when I yelled "Stop! You're cutting my spine!"
The 10:10 "No Pressure" commercial features people and children being exploded bloodily because they can't or won't come up with ideas for reducing carbon emissions, and is intended to be humorous this way. Unfortunately very few people saw the humor (it also starts very seriously, and the people-bursting comes completely out of nowhere, creating definite Mood Dissonance) and were deeply offended or disturbed instead.
See No Pressure (film) on That Other Wiki for details, since the Youtube version may have been edited.