The average adult male human body contains roughly five liters of blood (blood volume is proportional to body size). When donating whole blood, 450-500ml is normally taken, which produces feelings of fatigue and weakness for a while, and you must wait 56 days before doing it again. Red blood cells do not regenerate all that fast; that's why we have transfusions. While people can survive losing quite a bit of blood provided they get prompt medical attention, after losing 40% or more death is pretty much guaranteed.
But who wants to deal with all that when you're writing action (or comedy)? The more blood, the better!
Blood loss doesn't affect fictional characters so much, especially those in Video Games. No matter where they get shot or stabbed, it's "Only a Flesh Wound", even if it results in a geyser of High Pressure Blood that releases several times the blood volume of an adult human. Usually it's the flesh wounds that are what hinder the character; blood loss is rarely shown to be a problem to those Made of Iron (maybe they use that iron to make extra hemoglobin?). This can be taken to extremes when the player, protagonist, and enemies are shot so much they paint the walls red and create pools of blood on the floor, all with no ill effects other than a scuffed wardrobe (with little or no blood on it, sorry, White Shirt of Death) and artistically dripping blood. It seems the only ounce of blood (29 mL) that matters is the last one.
Not to be confused with Overdrawn at the Memory Bank, which features a lot less blood and a lot more stupid.
Before invoking this trope, keep in mind that five liters is still more than enough to make a HUGE mess. What looks like too much blood to a person who doesn't know what a gallon and a half of liquid looks like when spilled may in fact be entirely realistic.
Much earlier in the manga, Negi's students were worried that Negi was acting rather woozy and out-of-it. They eventually discovered that Evangeline had drained some of Negi's blood as payment for her Training from Hell. She actually states that she took "about the same amount you would give at a blood bank" the problem being that she was doing it every day when you're not allowed to give blood again for several weeks.
Used more often than not in the anime version of Bludgeoning Angel Dokuro-Chan, a series where the titular character often kills the main character with a spiked club only to bring him back from the dead seconds later. The very first death has blood, as a magazine review this troper saw said, 'spewing out all over the room like lava from a volcano', after Dokuro obliterates the protagonist's head.
Burn Up! sees Yuji have a nosebleed severe enough to flood the Coptown Police Tower in one of the omake-scenes in Excess.
Used with excessive glee in the anarchic world of One Piece: The sword-fighter Zoro regularly loses several pints of blood every time he has a major battle. The record, according to Word Of God, is six(!) or about two thirds of his total.
Zoro violates this trope so greatly that a rant at the fanficrants livejournal community about how fanfic authors needed to actually consider the ramifications of them injuring or causing that much blood loss with whatever characters they were writing actually referenced him as an exception, since it is perfectly normal (if not expected) that Zoro lose more blood in a single battle than most people have in their bodies, and Word Of God that Zoro lost 3 liters of blood in his first fight with Mihawk, and then 5 liters in his fight only a couple of days later(!) with Hachi and Arlong. The human body, on average, holds 5.6 liters of blood. So yeah. He should be dead. But it's okay! He survives with the power of Heart!
With Luffy this is actually justified: the Required Secondary Powers of being a Rubber Man mean his body produces blood at an impossibly fast rate to get to his stretches limbs, so he really does have more blood than a regular person.
Post time-skip, Sanji is working very hard to match Zoro, initially having regular massive nosebleeds just from looking at a woman. In Chapter 609, after a mild occurrence of Marshmallow Hell, Sanji suffered from a nosebleed so violent that it actually necessitated Chopper to ask everyone in the vicinity for a blood donation. While this may be the One Piece universe where blood floweth freely, Sanji had literally just lost what appeared to be roughly fifty gallons of blood. Through his nose.
This picture is probably needed to support the claim. Please do note that the giant fish in the foreground, and Sanji's nosebleed mermaid is in the background. If you look closely on the rocks beneath the nosebleed, you can probably make out a few silhouettes. These silhouettes are normally human-sized mermaids and fishmen, which means that Sanji essentially has enough nosebleed to shape a figure at least 100 times larger than a regular human. Even though it probably Runs On Nonsensoleum, Sanji still takes the prize for losing the most blood in One Piece, because he lost more blood than his body could ever contain.
At another point, back when they were sailing in a resin bubble at an insane depth in the ocean, Sanji had a nosebleed so explosive, it caused him to fly in the air from propulsion and caused him to fly through that bubble and away into the ocean.
In Episode 523 of the anime, they have a joke panel with Zoro, and nine pint bags of blood that was being transfused into Sanji. They made it look like they pulled all the blood from Zoro! In reality, it's blood Chopper already had stored on the boat. Sanji has a rare blood type, which becomes a plot point later on when Chopper runs out of stored blood and needs to find a donor. Zoro probably could donate that much blood, though.
Subverted in the Change 123. The author (committed as ever to technical accuracy, if not overall plausibility) comments on the effects of blood loss, and takes pains to apply it to the series' primary fighters, even throwing in some Death of a Thousand Cuts.
Though everyone in Saint Seiya bleeds a lot, Shiryu is notable for regularly geysering more blood than everyone else in his team has at least once per arc (the only time it's played fairly realistic is when he tears his own wrists open so Mu can fix up his and Seiya's suits. Shiryu went into a coma, and it's stated that he teetered on the edge of death, but he miraculously came back and was ready to fight again right then and there). It gets downright ridiculous in the Scorpio Milo vs. Cygnus Hyoga battle, during which the latter gushes out more blood than his entire body could possibly contain. And not only does he live through it —once Milo has realized the truth and stopped the blood loss via Pressure Point— but he's back on his feet and fighting at full strength not even five minutes later.
In Saint Seiya: The Lost Canvas, Capricorn El Cid actually uses this strategically. When fighting Icelus, an enemy that bends space to avoid and redirect attacks back at El Cid, he sprays a geyser of blood from a lost arm all around himself so that he could hear the resulting distortions when Icelus warps space. While he does die to blood loss, it's a good 2 episodes later afterkilling four gods inhabiting a single body.
Happens to ridiculous extents in Bleach. Partly justifiable in that most fights happen between spirit beings, but they do seem to have anatomy that resembles living creatures.
Originally, a Shinigami's body was described as being more-or-less a thin bag containing nothing but blood plasma. A Retcon and some Real Life years later, and they have much more humanlike anatomies, but still tend to bleed more than what a normal human would survive (well, they aren't normal humans anyway).
Absurdly overused in the manga Samurai Deeper Kyo. More then half the manga is a long continuous series of death matches for the main charachters who recieve about a couple dozen serious wounds each battle and usually one or two fatal ones. The is no regeneration factor ever mentioned, and there is only one real healer, and even she can only close open woulds, not internal which almost all the cast get at some point.
There wasn't a fight scene in Ga-Rei where the characters weren't bleeding. The main characters might have a Healing Factor, but even the ones that don't never bleed to death.
Teru Mikami from Death Note. He got a good three gallons by stabbing himself WITH A PEN.
Thanks to Synchronization with the Escaflowne and his status as the guy wearing red, Van suffers at least one coagulation-free day of bleeding from nearly every inch of his body while his friends futilely attempt to make it stop. While his blood pressure does drop low enough to cause heart arrhythmia and freak out The Medic, losing more blood than is contained the bodies of all of his comrades combined is apparently not enough to cause any permanent damage. Even knowing that he's half-Draconian pushes suspension of disbelief.
The disease from Emerging is most easily spread through the blood of the infected. Fortunately for the virus, its hosts have copious amounts of High Pressure Blood to spare!
Kodomo no Jikan manages to pull this off with a Nosebleed. It was 10 seconds long, and appeared to be a gallon a nostril. Two gallons of blood from a 3 foot tall 9 year old. She should be dead from that.
An episode of Magical Pokaan takes this trope literally by having the vampire girl giving daily blood donations, just so she could get the blood of the handsome guy running the donation cart. Throughout most of the episode, she's on the verge of death due to massive blood loss.
During Neon Genesis Evangelion whenever anything bleeds it tends to gush out blood in huge globs or jet like sprays. And the bigger it is, the more it bleeds. Some of these angels happen to be several kilometers/miles long, and when they die, their whole body shoots out tidal waves of the stuff. Logical conclusion: staining the moon in End.
Justified with the fact that it would need a lot of pressure in order to get the blood to circulate the body.
Deconstructed in Rebuild. Instead of exploding, the angels liquefy, and the sheer amount of blood floods Tokyo-3 every battle.
The manga of Gash/Zatch Bell has a bit of this. Look at Kiyomaro's death scene over here for example. Then again, he was dying, and most of it is probably just charring, it is in black and white. Maybe a better example would be reading most any battle chapter in either the 1000-year old Demon arc or the Faudo arc.
Saya from Onidere once has a nosebleed that flooded an entire room. While she's in it.
The manga is not quite as absurd, but still provides plenty of this trope in its own right. For example, Hyatt once got caught in a gas explosion in the bathroom, and Elgala looked in horror as her blood kept steadily pumping on the glass door. Then she walked out, completely unharmed.
Seems to happen in most anime/manga that feature blood. (It has been thought that an average anime/manga character has at least 12 gallons of blood in his/her body.)
Subverted in Fushigi Yuugi. The infamous Episode 33 (Or manga volume 8) where Nuriko dies. Nuriko is badly wounded in a fight with a "werewolf," but is still determined to get the Shinzaho for Miaka, and loses a lot of blood in the process. Much to the ire of the fangirls, Nuriko does not survive.
Several characters in Blood+ receive large injuries and spill a ridiculous amount of blood. Justified in that they're not humans.
Wolf Guy Wolfen Crest brings it up to One Piece levels, if not higher, with the final arc in which Akira—the werewolf protagonist who can take a blast from a shotgun to the face during the full moon with no ill consequences—gets stabbed in the abdomen, then runs dozens of miles to find the base his teacher has been stashed in, jumps an eleven foot fence, kills two attack dogs by punching them in the mouth, completely wipes out a group of guards armed with AK-47s while simultaneously being shot at by a gatling gun firing 4000 rounds per minute, runs through a field of anti-tank mines, gets some fingers chopped off by the Big Bad, gets sliced up with a katana, loses some more fingers and an arm, and still manages to save the day. Did we mention that this was during the new moon, when he is as weak as a human? He does die shortly afterward, though.
Mostly averted in Shiki. The exact amount of blood in a human's body is referenced often - since it's a series about vampires - but in the end there is a lot of blood gushing around from staking various shiki, who are stated to have even less blood than a human.
Subverted in the first TPB of Fables: Rose Red's apartment is found literally covered in her blood. Bigby the sheriff performs an experiment to see how much blood would be necessary to cover the room, and discovers it's over the amount of blood needed in humans to survive. In other words, she's dead...except she actually faked her death, with the help of her boyfriend: they took out a liter of blood at a time for a few months, stored it in the freezer, and when they had enough, used it to give the impression she'd been murdered.
Averted in one comic where X-23 attacked Wolverine, severed major arteries, and used dirt to stop them from closing long enough for him to bleed out sufficiently to pass out from blood loss. Of course most of the time Wolverine laughs at the idea that anything less than skeletonization could stop him. And even that's not a sure thing.
The end of Tokyo Gore Police. After getting his legs cut off by the main character and injecting himself with something, the villain spends the remainder of the film airborne on twin high-pressure blood jets.
The Bride chops Sophie Fatale's left arm off above the elbow, presumably severing all the brachial arteries, and she's left bleeding copiously on the floor without medical attention while the Bride fights Gogo Yubari, the Crazy 88 and O-Ren Ishi. According to a deleted scene, the Bride later severs Sophie's other arm below the elbow, before dumping her down a steep slope to a hospital emergency department. Somehow Sophie doesn't bleed to death...
During O-Ren Ishi's presented-in-anime origin story, her father is stabbed from behind by a thug (which O-Ren witnesses). Her father seems to swell before a cannon of blood spews out .
Played for laughs at the beginning of Tropic Thunder where a soldier suffers a headshot through his helmet and proceeds to spout a three foot high fountain of blood into the faces of his comrades, probably about three gallons in total.
In Dracula Dead And Loving It, Harker is instructed to hammer a stake through the heart of a vampirized Lucy Westenra. At the first blow, he is utterly drenched over several seconds by a geyser of blood from the coffin (which is why Van Helsing was hiding behind a pillar). Van Helsing handwaves it by saying she just ate. And directs him to hammer the stake again. And he does so. With the exact same results. Understandably, he declines to repeat the process. (And in real life, his actor was not told that he would get hosed down with red, and is visibly struggling not to laugh.)
Van Helsing: She's almost dead!
Harker: She's dead enough!
Also, Renfield gets a paper cut that results in a fountain of blood erupting from his finger.
The Saw films, shockingly, avert this. Throughout the series, the blood splatters are pretty realistic in size. Also, the victims that survive massive blood loss without dying (Gordan in Saw and Brit and Mallick in Saw V) show the effects of the blood loss.
It is interesting to note that Brit and Mallick apparently stop bleeding the moment they are no longer being cut, for no discernable reason. But that's a different trope.
Al: (Drinking beer) The brain doesn't need blood. It just needs to be kept wet.
Baltar in Battlestar Galactica loses quite a bit of blood in "The Hub" due to shrapnel before getting medical attention from Roslin. Then she takes off his bandages and lets him bleed some more in order to kill him (it's complicated). By the time she has an epiphany and tries to save him by reapplying the bandages (with no plasma on hand), there was a nice puddle on the deck floor. Baltar is nothing if not a persistent survivor.
Usually averted in anything involving Joss Whedon ... despite the copious use of bladed weapons, even non-human blood is thin on the ground (*ahem*) - see for example the final battle in Serenity where River ends up surrounded by Reavers that she has hacked to death with scarcely a drop of blood on the floor. Probably one to pin on the Moral Guardians.
Another, much more subtle, example: During the first 3 seasons, Bill feeds on Sookie roughly every other episode. The first three seasons take place over the course of, roughly, 2 - 3 months. Either Bill is drinking a teaspoon of blood each time he feeds, or she is regenerating blood at a absoluatly ridiculous speed.
The scene at the end of season 3 where Russell and Eric both feed on her for a while before walking out into the sun is especially noticeable, since she apparently has the strength to go out and retrieve their charred husks only a few minutes later.
Averted in The Wonder Years. When Kevin and his friends get caught skipping class and avoid punishment by offering the lie that they were going out to give blood, the show time-skips to the aftermath of their blood donation: each one of them is completely exhausted and barely able to stay awake.
Subtle example: In the CSI: New York episode "Cool Hunter", a young woman's bleeding body is dumped in an apartment building's rooftop water cistern. The cistern is big enough that it probably holds several thousand gallons of water, yet a single body's ~10 pints of blood somehow turns the water flowing from sinks and showers on the floors below a brilliant red, rather than it being diluted beyond visual detectability.
Riki-Oh / The Story Of Ricky, being a Bloody HilariousGornfest has this, specially when the warden is put in a meat grinder (the actor playing Ricky spent three days covered in fake blood after shooting that!).
The music video for Papa Roach's "Hollywood Whore" initially features said whore "passed out on the floor," as per the lyrics. Towards the end, however, she stands up and appears to sing along to the lyrics—then she starts to cry blood from one eye, which soon catches fire and burns off her entire face as she vomits enough blood to cover the stage (and the singer, who begins to resemble Bruce Campbell in Evil Dead.) It's . . . unnerving, to say the least.
Vampire The Masquerade has an odd reversal of this: stronger vampires could drink multiple times the amount of blood their body could possibly contain.
Invoked in the Innistrad storyline in Magic: The Gathering. On Innistrad there exists a cursed blade called the Bloodletter. This items is particularly coveted by the vampire tribes on the plane, because wound inflicted on a person by the blade will bleed infinitely, even after death. It doesn't actually kill the person, it just seems to make their body produce an infinite amount of blood on a wound that will never heal. On vampires, it seems to cause an inverted effect whereupon the cut vampire will be drained of all their blood and wither into a empty bag of dried skin.
Borderlands: One of the optional bosses in the game is a Scithid (basically a giant flying slug) called Bleeder. As the name implies, Bleeder is constantly bleeding huge quantities of blood. All the time. It bleeds about it entire body's worth of blood in about five seconds, and no matter how long it takes you to kill it, it will always have a seemingly infinite supply of the stuff.
Deus Ex: After taking so much damage, your character will start bleeding, and will leave a trail on the floor. Yet as long as you have some health left, you can bleed all you want with no ill effects.
Possibly justified by your character having nanomachine/robotic enhancements.
If anything the nanites should stop the bleeding faster. They can't increase the volume of his blood without swelling up his body.
Various MMORPGS, in which you can fight for a long time without worrying about collapsing if you have enough Hit Points.
Here's a fun activity: Log on to Final Fantasy XI with a high-level character. Pick a fight with a lower-level Notorious Monster of the Monk job. Now watch it use Hundred Fists and hit you countless times for minimal-to-no-damage while each hit causes you to bleed like a geyser. You could lose under a hundred HP, yet appear to have lost bathtubs full of blood.
Diablo II: When hit with a weapon causing the "open wounds" status effect, the target bleeds uncontrollably, leaving quite a large trail wherever they go. Of course, nothing actually affects their ability to fight until the Critical Existence Failure happens.
Doom, played with source ports with decals enabled: Every hit on an enemy near a wall will leave a blood splat on it. The shotgun is essentially several hits with one blast. Since some monsters have incredibly high Hit Points, you can basically paint the town(/dungeon/techbase/Hell) red when fighting one with the shotgun.
In Portal, Chell can take tons of turret shots, and leaves large blood smears on walls when hit. 5 seconds, and you're okay again, ready to lose another three pints.
No More Heroes. In the US version (which surprisingly had blood added to it), every Mook practically explodes with blood to the point where it loses all seriousness and can even be viewed as a form of Black Comedy. Bosses also do the same, except in more...creative ways.
In the first Halo, on the first level, if you kill Captain Keyes or any of the people operating on the bridge just for the hell of it, Cortana will seal the bridge and call in invicible marines to kill you. The marines are invincible, but still bleed when shot or pistol whipped. This can lead to situations where there's buckets of blood on the ground from one guy, and if you let up on your attacks for a second, he'll be shooting and cussing like you didn't do anything.
Hell, this goes for anyone in the game. Shoot up any dead body, and blood will squirt out, but you can make a lake of blood and still have plenty left.
In Halo: Legends, a series of 7 animes of varying styles based off of the Halo mythology, there is one titled 'The Duel.' The main character, an Elite/Sangheili named 'Fal,' goes into a duel with a Brute/Jiralhanae because Fal believes 'the cake Great Journey is a lie!' He loses, of course, and is stabbed by the Brute's weird samurai-esque sword-thing. Fal's chest then promptly explodes into a waterfall of purple blood.
In the novelization of the first game, an Elite is sniped in the head by a Marine with an anti-material rifle. The book lovingly describes a fountain spewing from where his head was for a good ten seconds before toppling over.
Mortal Kombat, from the very beginning, was known for the sheer volume of blood that would splatter during a match even without Fatalities.
In MK: Deadly Alliance, there are certain "missions" in which you have to make your enemy bleed a certain number of pints of blood within a certain time limit. The number was generally somewhere between 40 and 80. And they were still alive and well at the end of it.
Forget the blood, how about when the Fatalities cause the characters to explode with multiple rib cages and skulls and about 20 arms and legs flying out from one single mutilated body (for example, Sub-Zero's freeze-and-shatter fatality in the arcade version of MK 2)? More like Overdrawn At the Skeleton Bank.
Jagged Alliance avoids this in every possibility, by decreasing the performance of wounded mercenaries/soldiers and causing them to slowly bleed away their hit points unless the wound is properly treated. A gravely wounded soldier/mercenary will bleed to death within less than two minutes, and such wounds can only be treated by a medical expert. In Jagged Alliance 2, Enemy soldiers groan as they suffer from blood loss, giving away their positions, and every mercenary in the game has responses when they are moderately bleeding, and when they are about to die from exsanguination, complete with full voice recording. One custom player mercenary even lampshades this trope; "I have a rare blood type."
Dead soldiers/mercenaries do die in a pool of blood, but the amount of blood coming out is quite reasonable◊.
In the DOS game Liero, your worms will begin bleeding at low health. If you manage to survive for a long time, you would eventually produce far more red pixels of "blood" than could possibly fit in the worm.
The rate of blood letting can be changed, and you can even use a cheat app to up the gore still further,
The amount of blood lost to any attack in Neverwinter Nights seems to be constant, so it adds up to this over time on "Normal" violence level. On "Special," it's this within seconds (and Ludicrous Gibs when you land a finishing blow.)
FEAR, in the first game there are several locations (including a large multi-level elevator lobby) which are literally drenched in blood, far more than could be explained by the admittedly large number of corpses lying around.
Then again, all that is left of the people are skeletons. So it's more like their entire bodies were liquefied and then sprayed out all over the place.
Bad guys in the Dragon Age series seem to have far, far more blood than they really should, and delight in taking every opportunity to leave the scenery (and the player) drenched in it. The blood that gets on you tends to stick around for a while, but nobody ever seems to particularly care. This is especially odd when you consider that Dark Spawn blood is supposed to be poisonous.
The amount of blood is lampshaded at one point in the city elf origin. You're said to have enough blood on you to "fill a tub". During Zevran's cameo in II, you can point out that you're still covered in assassin blood while he and Isabela are flirting. "Invigorating, isn't it?"
And then there are Blood Mages, who regularly cut themselves and gush out at least a half-gallon of blood every time they cast their spells. At least there you can say A Wizard Did It. It also tends to float and swirl around, so it could be less blood than it appears to be, if it's coating a magical effect (which is to say, it could be like oddly shaped bubbles of blood - like an inflated balloon which is more air than plastic).
In Legend of Mana, there is a scene before a boss fight with a vampire where the protagonist is talking to an NPC with a bat on the ceiling above. About halfway through the conversation the NPC will mention the bat, who begins to drain blood from the protagonist. So long as you don't proceed with the conversation, the bat will never stop draining the protagonist's blood. Also, several techniques will cause those hit by them to spatter what looks to be gallons of blood with no effects other than the damage the skill causes.
In Dead Space 2, Isaac Clarke, the player controlled character, gets slashed or grappled regularly (depending on your skill), losing gallons of blood each time.
Team Fortress 2 has standard First-Person-Shooter blood 'decals', that appear every so often. When combined with the recuperative effects of a friendly Medic though, you can lose a lot of blood without ill effect.
Additionally, the Sniper has the Tribalman's Shiv, a wooden kukri that inflicts wounds that persistently bleed out for the next eight seconds, after which you Walk It Off. Not even Dispensers or Medics can stop the bleeding.
The Demoman's unlockable melee weapons, The Eyelander and The Scotsman's Skullcutter both cause massive bleeding and High Pressure Blood spurts when they decapitate an opponent.
The Medic's Crusader's Crossbow allows you to shoot several arrows into your teammates to heal them causing bleeding wound decals and visible arrows to be left behind. Hilarity Ensues.
Shades in Nier gush out awe-inspiring fountains of blood, and the bigger the Shade, the more blood there is to gush. It has a certain internal logic —Grimoire Weiss uses Blood Magic, and thus absorbs the blood of any Shade slain by the main character (though not those slain by his companions) in order to create his magical constructs.
Although bleeding your enemies out is one of the ways you can kill an enemy if Dwarf Fortress (the others being bisection, decapitation, and suffocation), the amount of blood a creature loses before finally dying can be surprisingly large. Especially with the glitch that causes infinite blood tracking; the blood of a single groundhog can theoretically be used to paint the floors of an entire fortress blood red by getting stuck on a dwarf's boots and spread around without actually decreasing.
When Meat Boy walks, jumps and runs, blood splatters around him, leaving blood stains everywhere.
The Splatterhouse series, but it's recent reboot/remake takes the proverbial cake. If the name alone wasn't hint enough, you'll know what you're in for when just punching a single enemy spews enough blood make even Mortal Kombat seem tame.
Subject 16/Clay Kaczmarek of the Assassin's Creed series managed to cover an entire room with paintings using his own blood as a medium. While the human body does have enough blood to make that kind of a mess, it's a bit of a stretch to believe that he managed to finish without passing out.
They Bleed Pixels measures the player's score in "pints". Just smacking around one shambler without any combos will give you nine pints, which is a fair value given their body size, but some of the combos can cause ludicrous blood spray, both score-wise and graphics-wise.
In Hitman: Blood Money, a puddle of blood slowly forms under dead NPCs. However, there are also a few animals in the game you can kill, and these get exactly the same size blood puddle. Since these animals include a tiny dog and rats, these get a hilariously huge puddle of blood.
Paradigm Shift has the heroine, Kate, get shot and bleed out far too much to have walked it off like she did. However, this is intentionally done to highlight her Healing Factor and the eventual reveal that she's a werewolf.
8-Bit Theater combines this with High Pressure Blood to make some truly epic gorefests, although in fairness, most of the cases of people spurting that much blood are actually fatal, even if it's far more than could possibly be in their bodies.
In Homestuck, Vriska shows this after being curb-stomped by Aradia. She manages to bleed out like, ten gallons of blood before she dies. Andrew Hussie being well, himself it gets a Lampshade Hanging (see the quotes page).
The Rules Of Animetalk about this, among other reality defying feats in anime. It's called "The Law of Hemoglobin Capacity," and goes something like this: "The human body contains twelve gallons of blood, sometimes more, under high pressure."
The season 11 episode of The Simpsons "The Mansion Family" had Marge win an award for donating the most blood. She soon gets dizzy and falls asleep (There are limits to how much blood you can donate. If Marge got tired easily, she could be anemic, and the blood bank probably shouldn't have let her donate in the first place. This is, of course, if the show were based on anything resembling reality).
Robotomy had this on the second episode, "Bling Thing," only instead of "blood," it's "coolant" (since Blastus and Thrasher are robots), and donating too much causes such bizarre side effects as jitters, paranoia, fire blisters, and rectal whistling.
Taken to ridiculous extremes in the early Beavis And Butthead short "Blood Drive" in which the duo give blood, the nurse never takes out the needles and all of their blood is sucked in the enormously engorged bags and they are skinny shriveled husks.
Dilbert: One episode had a bizarrely literal example, the company had a blood drive that Dilbert volunteered for but nobody else did, too bad about the quota.
Peggy and Minh of King of the Hill get into a blood donating spree during one episode, trying to beat the other to a free coffee mug. They both spend the episode anemic, and weak from so much donating. Peggy wins, even though she can barely move and has to literally drag herself into the back yard to brag to Minh about her "victory".
Insects have (green) blood that surrounds all of their organs and fills their exoskeletons. As biologically accurate as it was, Deadly Creatures should have ended up looking like a Tarantino film.