Frog: Hey, mister, this here's the stairway to heaven. Ya know that, don'tcha?Use of mind-altering substances distorts the world. Sometimes, the hallucinations are passed off as a side-effect of overconsumption of an otherwise legal and legitimate foodstuff such as sugar, ice cream, chocolate, or steak sauce. What makes this trope generally different from Intoxication Ensues is the hallucinations. The narrative might jump back and forth between the hallucination and the real world to show they are holding a normal, intelligent conversation with a plant. Typically great comedic fodder with a believable setup. If it's animated, expect those affected to Open the Iris. If it doesn't contain An Aesop about the dangers of drug abuse with Anvilicious subtlety, it tends to just show off a character's carelessness. May involve a G-Rated Drug. See also Acid Reflux Nightmare for a food-related version. Sometimes leads to a Disney Acid Sequence. If it's a whole group of people experiencing it simultaneously, it's Everybody Must Get Stoned. See also Through the Eyes of Madness. Also often tied into Drugs Are Bad.
Spike: Obnoxious little frog.
Spike: Obnoxious little frog.
— Cowboy Bebopnote
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Anime & Manga
- Cowboy Bebop features the Trope Namer episode "Mushroom Samba": The crew confuses "magic mushrooms" with the regular sort, with the result that Spike ends up meeting a talking frog on an endless stairway, Faye steps into the water closet/loo and ends up in the ocean with fish going by, and Jet starts talking to his bonsai plants ("So that's it? I never realised the secret of the Universe was so simple! So by the way, who am I exactly?"), leaving Edward and Ein to track down the crook of the week. This is after Ein has taken a small bite from one of the magic mushrooms and spent some time hopping around stiffly like a clockwork dog.
- Samurai Champloo
- There's an episode where a field of "grass" was set on fire, with... interesting results.
- Another episode is closer in spirit to its Cowboy Bebop predecessor, where the heroes run into zombies and they and the viewer are partially left to question whether or not it was the result of some "wild mushrooms" they consumed at the episode's beginning.
- One Piece
- During the Alabasta arc, when the crew wanders through the desert, Luffy accidentally eats the wrong kind of cactus, and apparently hallucinates about enemies. He also hallucinates about a tidal wave (in the middle of a desert?!) and tries to beat it up.
- Despite Luffy being the Idiot Hero, he has a considerable amount of useful (and questionable) knowledge. Some of the questionable knowledge was shown when he first arrived in Amazon Lily, where he shows too much knowledge about hallucinogenic mushrooms (and start eating them in speedball fashion to cope with the fact that he lost all of his crewmates and couldn't do anything about it).
- Kimagure Orange Road has the cast in a field trip searching for rare blue mushrooms that would force anyone who ate them to tell the truth or act as their true self; naturally with the intent on using it on each other. To prevent this, one of the ESPers (Kurumi, male lead Kyosuke's sister) uses her powers to turn EVERY mushroom blue. As the characters contrive to feed each other fungus, various zany situations crop up due to the apparently behavioural-altering effects of common mushrooms.
- Sato's delusions from Welcome to the N.H.K. are heavily implied to be this in the manga. In the anime they're implied to be schizophrenia. In the novel they're explicitly attributed to drug use.
- In the Dragon Ball Z movie Dead Zone, Gohan eats an apple growing in Garlic Jr.'s garden. The minion guarding him goes nuts, telling Gohan that "Children can't eat those. They see things." Cue drug-trip montage.
- A variant occurs in Eyeshield 21, where after the game against the Nasa Aliens, Sena starts hallucinating out of exhaustion.
- In the manga Yamada Taro Monogatari, Taro is given a bag of "flour" from a rich classmate, and uses it to cook pancakes for his family. Later, it is revealed that the huge bag of flour was actually narcotics made from magic mushrooms. However, due to being extremely poor and starved most of the time, Taro and his family were able to digest it with no problems or side effects.
- In Air Gear, Ikki and Shiraume end up consuming some funny Matsutake mushrooms, with some rather interesting effects. They end up 'fixing' one of Ikki's trecks and turn it into a formula racing car. In the living room.
- Ninin Ga Shinobuden has a large-scale one when the ninjas get some bad mushrooms while mushroom hunting. Then Onsokumaru eats some. Insanity ensues.
- In episode 4 of Queen's Blade, Reina tries eating a large, spotted mushroom for sustenance. Unfortunately, we don't get to see what she sees.
- During the infamous island filler arc of Nadia: The Secret of Blue Water, Jean enacts this trope with actual mushrooms. During his hallucinations, he even visions Marie as a moving turkey dish. Hilarity Ensues.
- The chocolates in episode 15 of Brigadoon: Marin and Melan produce... interesting... hallucinations in both the title characters. Leads to Intimate Healing.
- The Highschool of the Dead filler OVA episode, Drifters of the dead has the group unintentionally drug themselves by burning toxic hydrangea leaves, causing them all to hallucinate. And this being High School of the Dead the hallucinations get a little explicit.
- In Black Lion Shishimaru sets a field full of marijuana on fire causing Gennai Doma to hallucinate that there are multiple Shishimaru's and mutant scarecrows everywhere that he continuously cuts down with his sword.
- In Urusei Yatsura the class eats Nabe and Cherry brings mushrooms which taste like Matsutake mushrooms...
- In the Bannertail: The Adventures of Gray Squirrel episode "Akācho and the Flying Mushrooms," Akācho, wanting his (perceived) rival Banner out of the way so he can spend time with Sue, happens upon him eating acorns and says he has something much yummier, leading him to some red mushrooms which he tricks him into eating. The unfortunate young squirrel promptly experiences a lengthy tripout sequences wherein he mistakes his friends for predators and viciously attacks them, needing to be subdued.
- This is actually one of the mutant powers of X-Men member Pixie: secreting a hallucinogenic dust that makes people see bizarre things. It even made Wolverine run around the mansion trying to kill "freakin' unicorns!"
- One of the Marauders (not to be confused with the Harry Potter prankster group) is Vertigo. Her power screws around with spatial perception, causing an absolute loss of perspective as well as intense vertigo.
- In Animal Man Buddy and Dr. Highwater are led by a series of bizarre signs to the desert. On a mountain they find some peyote buttons and decide they are supposed to take them. When they do take them, a multiple issue trip involving talking animals, eyes appearing in the sky, and one of the characters 'killing themselves' ensues.
- Happened to Hal Jordan in one of his back-up Green Lantern strips in The '70s with literal mushrooms, which he had picked wild and put into his chili.
- At some point in one of the Cerebus the Aardvark story arcs, Cerebus is out and about with Prince Mick and Prince Keef, and Mick gives him... something which later causes Cerebus to observe, "... we're all PLANTS! Cerebus can feel it!" He spends the next few frames hallucinating that bits of his face are falling off, and scrambling after them to reattach them "before the sap freezes".
- The one and only full-color sequence in Sin City involves Wallace, the protagonist, getting drugged by an enemy. He then has to get in a gun fight and Car Chase alongside his former commanding officer. The landscape looks like Frank Miller was channeling Dr. Seuss. During this time, the commanding officer morphed into Hellboy, Rambo, and even a beautiful woman.
Commanding Officer: Are you looking at my ass, son?
Wallace: Sorry, sir.
- In Superman & Batman: Generations, Dick Grayson as Batman is tricked into falling down a shaft lined with razor blades that are coated with hallucinogenics, so when he ends up fighting the Joker posing as Joker Junior, things get...really weird.
- In the Lucky Luke episode The Ballad of the Daltons, an Indian witch doctor spikes the Daltons' drink with mushroom powder, giving them some pretty weird hallucinations.
- Jesse takes some peyote to commune with genesis late into Preacher. The effects are... not pleasant.
- In the hilarious yet short lived 2001-2 comic Pink Chickens there is a scene where the girls ingest large amounts of colourful sludge they find in the ships fridge, after which they find out that its actually liposuctioned alien fat, then they find out its a hallucinogen, hilarity and missing panels ensue.
- In Druid City, the lead character Hunter experiences a mild hallucinogenic episode after drinking a dangerous amount of alcohol directly after it is implied that he smoked marijuana. This was done deliberately so that he would not recall an unpleasant experience. This little incident starts here
- Hourman apparently had one during a test run of an "improved" Miraclo pill formula in JSA: The Golden Age. He flatly denies it in his monologues.
- In one issue of the French comic Rahan, the eponymous caveman gets a nasty nightmare after eating some unknown mushrooms while starving during a crossing of the desert. At first he believes himself to be dead and to have reached the afterlife, populated with winged serpents and a huge two-headed dinosaur that devours him.
- At the climax of League of Extraordinary Gentlemen Century: 1969, Mina takes tadukic acid in the hopes that the heightened awareness will help her find Haddo's cultists. Thus, she has a frightening drug trip that eventually leads to an out-of-body experience and a fight with Haddo's spirit. And the whole scene is set to a version of The Rolling Stones' "Sympathy for the Devil". The scene ends with poor Mina going temporarily insane and getting committed to a mental hospital, while Haddo goes on to possess a certain professor named Tom Riddle...
- Zippy the Pinhead: Zippy, in Acapulco as an unwitting drug mule, is dragged off to a pool party full of jaded rich hedonists. He happily gobbles up all the recreational drugs scattered around like they were party snacks, and starts hallucinating wildly — but he seems his usual self.
- A story arc in Bloom County had Oliver extracting the hallucinogenic chemical from dandelions for testing, only for his father to drink the entire beaker. He ends up in the tool shed, yelling about Erik Estrada coming out of his belly button.
- One censored Garfield comic which only appears as a rough sketch in the 25th anniversary book, features a half asleep Garfield as he watches a periscope emerge from his water dish, followed by a tentacle. Garfield then smiles and says, "Man, that was some gooooooood catnip!"
- I'm a Marvel... and I'm a DC
- The Green Goblin has a really powerful sedative injected into him to numb the pain while his superpowered healing system deals with being run over by the Batmobile. He has some really funny hallucinations as a result.
- When Batman does the same to Luthor, this results in the both of them hallucinating. And singing.
- In Six Days The Animorphs Were Idiots, the brightly colored clouds on the Animorphs book covers are explained as being a result of Marco's illicit drug use.
- Touhou Mother
- A parody of the Tanetane Island sequence from EarthBound has Marisa as the player character for that section because she's already used to the effects of magic mushrooms.
- Satori gets infested by the confusion-inducing mushrooms, causing her to behave impulsively and spontaneously proposition Mima. Afterward, she's too embarrassed to even speak with the party.
- In Black Queen, Red King, ordinary candy heartsnote acts like a combination of weed and LSD for changelings. It also restores their sense of taste (much to their delight) and makes them involunarily secrete binding gel.
- John Gage is injected by a druggie in the Emergency! fic "Blind Faith'' and has one. Roy has to talk him out of swinging a fire extinguisher at the fires only he can see, thinking he's saving his crewmates.
- Nick of the Warblers in Hunting The Unicorn has a really bad trip after coming out bisexual to his less-than-informed mother. He only remembers getting high to piss his mother off, going to Trent's place and getting drunk, then waking up in Jeff's room with glass in his boots. Flashbacks reveal that Nick and Trent kicked out Nick's mother's headlights. Thad later drove him to Jeff's place, where Nick thought he was turning into a bird, hallucinated that his cousin Sarah's fiance was a barn owl, and said "I love you" to Jeff.
- The Mist from Angel of the Bat is a potent hallucinogen that leaves those inhaling it in a state vulnerable to absolute horror. The Seraphim combines this with inkblots and violent imagery to try and break his captives. All that’s known about the drug for sure is it is very hard to detect and contains Scarecrow’s fear toxin.
- Dragons under the effects of Angel's Folly experience this in The Legend Of Cynder Series, in addition to it locking their powers. Cynder herself states she sees three Sparx' when the sky pirates use it on her to keep her from escaping.
- In chapter 17 of ''Evangelion 303 Mari got some LSD as a party favor when she went to a strip club. We see part of her trip at the end.
- Supermarioglitchy4s Super Mario 64 Bloopers:
- The episode "99.5% Crazy" revolves around Mario getting high off a Poison Mushroom and staying that way for the whole blooper until he is cured buy a random 1up Mushroom that crawls into him.
- Mario goes high from several more Poison Mushrooms (and even from an overdose of pills) over the course of the series, with one instance ("Yoshrooms") having Yoshi join him for the ride.
- Luke Skywalker gets some Jedi-affecting shrooms that are presented as a gift when he's at an diplomatic dinner in the Star Wars fic It's A Jedi Thing, You Wouldn't Understand. He winds up on the roof of the building, with a stick as his lightsaber, totally naked, retelling Han and Leia about Bespin.There are also some defaced garden statues involved. Han stuns him with his blaster to get him out of there. Luke later vanishes and Mara Jade (in the era before she was his wife) finds him singing bad karaoke in a bar. She keeps him from wandering off again but he's also rather amorous while he's intoxicated. Oddly though, they do end up having an enjoyable encounter later, and want to get together again. She does make him promise not to eat anymore mushrooms though.
- Ultra Fast Pony.
- In "To Kill a Firebird", Twilight and Fluttershy are trying to cure the bird Philomena, and Twilight forces a pill down the bird's throat. She thought it was medicine, but Fluttershy points out, "Oh no, that's my acid!" We don't get to see the bird's hallucinations, but she's high as a kite during the chase scene that immediately follows.
- That raises the question of why Fluttershy had acid in the first place... and "The Penny and Clyde Show" hints at the answer. When Discord's wave of chaos overtakes Ponyville, the other ponies become distraught, but Fluttershy just stands in the chocolate milk downpour, looks at the rabbits transforming into long-legged monstrosities, and remarks, "Oh, this is just a normal day for me."
- Steven manages to get high off some Scorpion Powder in the first chapter of Starchild and wildly hallucinate about, among many things, a rabbit and the priestesses who helped raise his mother accusing him of Parental Incest. It takes being whacked across the head to snap him out of it.
Films — Animation
- One of the most classic Mushroom Samba scenes was in Disney's Dumbo, where Dumbo drinks from a tub of water laced with champagne, and has a wild and disturbing musical fantasy sequence about "Pink Elephants on Parade". That must've been some champagne. In Real Life, zoopsia (the hallucination of animals, including Pink Elephants) is a symptom of sustained alcohol abuse. Although elephants are terrible at holding their liquor. Most elephant-related fatalities are also alcohol-related. On the elephant's part.
- In Beavis and Butt-Head Do America, Beavis eats some peyote and goes on a hallucinogenic trip seeing himself and Butt-Head as rotting zombies and freaky demons everywhere playing the guitar, driving mini cars, etc., set to some trippy music performed by Rob Zombie ("Ratfinks, Suicide Tanks and Cannibal Girls"). The scene was based on drawings of Rob Zombie's, the music was actually from Rob's now-defunct band White Zombie.
- Alex the Lion from Madagascar has a brief one after getting hit with a tranquillizer dart. Twice.
- Lucky Luke: La Ballade des Dalton has one after the Dalton Bros. drink mushroom-laced water.
- In The Dagger of Kamui, the progatanist Jiro and his newly found mother eat soup and then break into unexplained hallucinations. It was later revealed the soup was laced with poison by a minion of the film's baddie.
- Happens literally in the movie The Elm-Chanted Forest when the hero is captured by talking mushrooms, who proceed to do a whole song-and-dance routine about how awesome it is to be a mushroom. At the end of the routine, they all suddenly grow fangs. It's loosely implied that this is because of something they gave him to turn him into a mushroom himself.
- Heavily implied in The Road to El Dorado. While in the middle of singing "It's Tough to be a God", Miguel and Tulio smoke some cigars, and the song turns into a full-blown Disney Acid Sequence.
- They were also drinking "Punch" throughout the song, and getting wierd looks on their faces after each drink.
- In the Astérix movie "Asterix In America" after the medicine man drugs Asterix and Obelix with a Peace Pipe so he can capture Getafix so he can make him the strength potion, after Obelix wakes up he hallucinates that Asterix is a giant fanged buffalo and he runs away when he approaches him.
- Happens in The Good Dinosaur to Arlo and Spot when they eat old fruit that fermented in the sun. Both giggle like they're high, Arlo grows extra eyes, they scamper around together each with the other's head on his body.
Films — Live-Action
- The League of Shadows' blue flowers and Dr. Crane's fear gas/spray from Batman Begins seem to qualify. Decidedly not played for laughs, and in fact is used as a panic-inducing plot point.
- Subverted in Euro Trip where two of the movie's protagonists, predictably, decide to visit an Amsterdam bakery/coffee shop and trip out on hash brownies. Jenny gets the munchies while Scott simply freaks out (including the random, memorable confession "I saw a gay porno once. I didn't know until halfway in. The girls never came. The girls never came!"). When it gets really intense, the chef informs them that they do not serve hash brownies, meaning that the only thing they were high on was the placebo effect.
- It doesn't help that the bakery was owned and operated by Jamaicans. Who claim the brownies are "magical."
- Tenacious D in The Pick of Destiny had JB eating mushrooms in a forest and going on an extended Dream Sequence in which he was the son of the Sasquatch. He ends up nearly drowning and falling off a tree.
"Huh. This place is kinda.... JUICY."
- Star Trek IV: The Voyage Home: Kirk tries explaining off Spock's alien behavior on 1986 Earth by saying that he suffered brain damage from too much "LDS" back in the sixties. The whale scientist doesn't buy it.
- In Beverly Hills Ninja, Haru, interrogating a source, uses a powder made from the "laughing mushroom" as a Truth Serum. However, he sneezes on it, he and love interest Sally Jones also inhale a dose, and the three sit around laughing their asses off at the most frightening and depressing truths.
- In Salvador, Doctor Rock (James Belushi) slips some LSD into an American TV journalist's cocktail. In the next scene she's talking to the camera, then suddenly sinks to the ground in a fit of laughter.
- In Lethal Weapon 4 Riggs, Murtaugh and Detective Butters are trying to get a Chinese mob boss to talk, so they sneak in on him while he's at the dentist and give him a snort of nitrous oxide. Unfortunately Butters leaves the inhaler on, so everyone in the room gets a little loopy, leading to the reveal that Butters has gotten Murtaugh's daughter pregnant.
- Most of the movie Altered States consists of Mushroom Sambas... but they are hardly unintentionally induced, as the main character who undergoes them is researching the very drug behind the phenomenon.
- Played straight in Labyrinth, Sarah is given a "present" from Jareth - a peach which either causes her to hallucinate or actually transports her to a masquerade ball inside a crystal. There's also a possibility that the whole Labyrinth and such were hallucinated by Sarah, possibly because of a magical owl.
- Central plot device in the black comedy Death at a Funeral, whereby a pharmacology student creates an experimental designer drug and stores it in an empty Valium bottle. Throughout the movie Mushroom Sambas occur when the hallucinogenic pills are accidentally taken by three characters attending a funeral service. Hilarity Ensues.
- Empire Records: Mark eats Eddie's "special brownies" and proceeds to hallucinate himself into GWAR's video for Saddam A Go-Go from the album This Toilet Earth, then getting eaten by the World Maggot (the same thing that ate Jerry Springer when GWAR was on his show). He seems to find all this very funny.
- Reefer Madness, with the pot brownie scene.
- In the 1996 film William Shakespeare's Romeo + Juliet, Romeo (Leonardo DiCaprio) is given an ecstasy pill right before going to the Capulet masked ball — putting Mercutio's "Queen Mab" speech in a different light altogether. Some seriously trippy imagery from his perspective ensues.
- In 1996's A Very Brady Sequel, conman Trevor Thomas is served hallucinogenic mushrooms in a plate of spaghetti by clueless maid Alice; the subsequent sequence features animation (including dancing pandas and a helicopter-tailed wizard bird from the Filmation The Brady Kids cartoon) and the trippy Sixties anthem "Good Morning, Starshine" from Hair.
- Across the Universe uses this. It's also taken to a greater level with all the visual imagery used and the fact that the music is by The Beatles...
- In Freddy's Dead: The Final Nightmare, Spencer, played by Breckin Meyer, sees all kinds of trippy imagery coming out of the TV, set to Iron Butterfly's "In-a-gadda-da-vida", and ends up in a video game.
- In A Serious Man, the protagonists son Danny becomes a Bar Mizvah stoned.
- The Bear: The eponymous bear cub finds some toadstools and, curious, eats some. He spends the next few minutes tripping out and whimpering, which is to be expected given what he sees.
- In Go Manny takes a handful of ecstacy and while in a grocery store starts hearing 'Macarena' and hallucinates that he is dancing with the checkout lady and they are feeding each other bananas.
- In Suck, Joey mistakes two ecstasy tablets for aspirin before going out on stage. The result: an aptly titled musical number "This Is Your Brain On Drugs" with distorted colors and visions of three vampire band members leering at Joey.
- In Bad Lieutenant Port Of Call New Orleans, in what is probably the film's best-known sequence, the protagonist snorts some heroin that he thought was cocaine, snorts some actual cocaine to try to balance it out, and ends up hallucinating about iguanas. Later on, after a climactic shootout, he orders that a dead man be shot again because "his soul is still dancing!" And the camera switches to his perspective to show that, yes, he is hallucinating the man's spirit break-dancing over his body.
- The Canadian film Men with Brooms had a lead character whose father was a regular 'shroom user. There were plenty of jokes about it, though no explicit hallucinatory scenes onscreen.
- When Jerry of Conspiracy Theory is first captured by Dr. Jonas, his system is pumped full of LSD to make torturing him easier. His hallucinations and distorted perception of the world are notably played for drama rather than laughs.
- In Snow White and the Huntsman, The Dark Forest is feared as a hellish landscape with monsters, vermin, Body Horror, etc. The Huntsman, one of the only people to enter the forest and return alive, explains that while the forest does have a few monsters in it and is treacherous, the real danger is the hallucinogenic spores.
- A Field In England features a twenty minute eye-bombing sanity-stripping example, with flash-cuts, mirror effects, swirly lenses, the works. Word of God states that a feature film normally has about six hundred cuts. This film has fifteen hundred cuts in the fifth reel alone.
- In Upstream Color, a woman is hypnotized by a thief who tells her that his face is made from the same substance as the sun, so she cannot look directly at him. From her perspective, we see her flinch away from bright light coming from the thief's direction.
- The Lightning Thief: The effect of the lotus blossoms, apparently.
- Used as a murder weapon in Young Sherlock Holmes.
- In Fathers Day 2011 Twink and Father Sullivan find Ahab's (toxic) berries and eat them, setting off a hallucination sequence. They even feed some to the passed out Ahab.
- Oscar's drug trip in Enter the Void which we see from his POV. It's probably one of the more realistic trips shown on film.
- In Road Trip after Barry's grandpa eats some of E.L.'s pot brownies he hallucinates that his dog is talking to him:
Dog: Hey old man I got the fucking munchies real bad!
- The Hunger Games: When Katniss is stung by the poisonous Tracker Jackers. This is admittedly Lighter and Softer than the book's presentation of the events.
- In Book 4 of the Lone Wolf series, The Chasm of Doom, while in the Maaken Mines, breathing the spores of Calacene mushrooms can cause the hero to hallucinate of a fiendish monster (or a whole swarm of them). The "fight" that ensue cause real damage, however, since Lone Wolf keeps throwing himself against the sharp rocks of the tunnel.
- The late-1960s Hugo-nominated novel The Butterfly Kid by Chester Anderson involves a plot by pacifist aliens to take over the world by overdosing humanity with a drug that causes solid, physical hallucinations that can be seen by people other than the one taking the drug. The idea is that human beings will find this so confusing that they will be rendered helpless. This does not work; the humans are all hippy stoners who enjoy the experience, generating creative hallucinations.
- In A Lion Among Men, The Lion meets some bears who act like stoners. On Honey.
- In Bored of the Rings, Frito eats some mushrooms and pills provided by whacked-out wayside hippie Tim Benzedrine and hallucinates until he passes out.
- In Dora Wilk Series, after the main character is drugged so that she'd stop fighting, she has a darkly comical trippy sequence which would be funny if it wasn't for the fact that she's in the middle of a rite whose purpose is to plant a demon in her soul.
- In Small Gods, Brutha meets a hermit, St. Ungulant, who lives in the desert, and occasionally eats mushrooms:
St. Ungulant: The desert becomes really interesting after the mushroom season.
Brutha: Full of giant purple singing slugs? Talking pillars of flame? Exploding giraffes? That sort of thing?
St. Ungulant: Good heavens, yes. I don't know why. I think they're attracted by the mushrooms.
- In Robert E. Howard's The Hour of the Dragon, Conan the Barbarian sees Xaltotun using the black lotus.
''It was the pollen of the black lotus, which creates deathlike sleep and monstrous dreams; and he knew that only the grisly wizards of the Black Ring, which is the nadir of evil, voluntarily seek the scarlet nightmares of the black lotus, to revive their necromantic powers.'
- Cryoburn opens with this. "Angels were falling all over the place... Ah, terrific. Auditory hallucinations, too."
- Soma is a regular cause of Mushroom Sambas in Brave New World.
- In George Alec Effinger's Marid Audran series, Bill the cab driver has had one of his lungs replaced with a container of a powerful hallucinogen, which continuously drips into his system. When he drives, he constantly swerves to avoid obstacles no one else can see, and holds conversations with the demons in the front seat of his cab.
- In "Steppenwolf" by Hermann Hesse the suicidal protagonist is rescued from his lonesome misery by some friendly strangers and their charming cigarettes. They take him to their 'Magic Theatre'(Not For Everyone/For Madmen Only/Price Of Admittance Your Mind) and they indulge in many drugs and Harry spends the last third of the novel reveling in hallucinatory adventures. At the end of the novel he snaps out of it briefly and is told that he has been in the Magic Theatre the whole time and making rather a fool of himself, but its okay and they give him another hit.
- Bloody Jack in Viva Jacquelina! a starving Jacky discovers some mushrooms growing on some manure, with the predictable results (including seeing a White Rabbit and talking to Brer Frog). When she comes down, she picks up more of the mushrooms to experiment with on other people. Not What It Looks Like Ensues
- The Purple Pileus by H. G. Wells is a short story about a man whose crappy life is changed for the better after he trips out on some mushrooms he finds in a wood.
- The Hunger Games: A (mostly) extremely unfunny version thanks to Tracker Jacker venom.
- Jules Verne's Around the Moon involves an incident where the group on the space capsule begins having bizarre arguments about the "moon people" (whose existence has only been speculated on with no evidence at all). It ends with each of them claiming to be the true leader of the moon. Then one of them realizes that someone left the Oxygen valve open and they've been getting high off pure O2 for hours.
- On Workaholics the main characters do drugs fairly often, but in the episode "Business Trip" the guys (with the exception of Ders) do acid, along with Alice, Karl, and a potential Tel Ameri Corp client. Adam gets a bum tab, but Blake and Adam both freak out-Blake sees a worm alien monster trying to attack him, and Alice mistakes a chair for being Spanish and also hallucinates eating a hotel reception desk like its jello.
- Most episodes of That '70s Show have either implied or obvious cannabis use. One Samba moment happens when Eric goes upstairs to make toast and runs into his father, Red; while they talk, the wall in the background is moving. Also, Red once accidentally eats a "special brownie" made by the kids. Hilarity Ensues.
- Kitty voluntarily smokes a joint in the bathroom, and sees Red and Hyde's bodies morph.
- House uses LSD to beat off a self-induced migraine (which is another story). "I'm seeing sounds!"
- And Wilson, when House loads his coffee with sppppppeeeeeeed to see if Wilson was on anti-depressants.
- On another episode, House uses psychedelic mushrooms to treat a particularly obnoxious teenager's cluster headaches... he mellows out some. (Cue Iron Butterfly and swirling colors.)
- In season 8, Dr. Chi Park inadvertently ate some LSD-laced ice cream, seeing Chase as a rabbit, Adams as a sexy wolf, Taub as "either a tooth fairy or Rainbow Brite", and House as...well...House.
- The George Lopez Show features a drink involving a worm at the bottom of the glass. Drinking the worm induces an instant Dream Sequence episode.
- Life on Mars has a sequence in the second season where Sam is accidentally given an overdose causing him to experience several hallucinations and a memorable Dream Sequence where he and Gene are stop motion characters in children's show Camberwick Green. The best bit was probably Gene "beating up a nonce."
- In the Coupling episode "Jane and the Truth Snake" Jane takes two paracetamol in a failed suicide bid, not having grasped the concept of an overdose. The pills actually aren't paracetamol but something she was given at a party, and Hilarity Ensues as her excessively straight-talking alter ego takes control in the form of a talking snake puppet.
- In an episode of My Name Is Earl, Randy eats hippy face lotion and begins to see everything in claymation.
- While in the Deadly Swamp in The 10th Kingdom, Virginia and Tony consume magic mushrooms (and drink swamp water, which is apparently some form of alcohol). What makes this especially amusing is its literalism: while the mushrooms don't actually dance, they do sway in time to the music and sing their consuming victims to sleep (to Procal Harem's "Whiter Shade of Pale" no less!). Cue Dream Sequence. But although the mushrooms seem hell-bent on their own suicidal destruction, this is subverted by the fact that it's all a ploy by the sentient man-eating swamp to shroud its victims in vines so they can be crushed, suffocated, and eventually consumed in turn.
- Six Feet Under. David stows the E tablets he received from his club-hopping boyfriend in an aspirin bottle in the family kitchen. Ruth goes camping and packs the aspirin in her first aid kit. After getting a headache she does some serious wandering around in the woods. (See also Intoxication Ensues for other repercussions.)
- In Pushing Daisies, Aunt Lily takes an overdose of homeopathic mood enhancers and starts hallucinating.
- In some of the early episodes of The Goodies, Bill Oddie's hallucinations are crucial plot points. They are induced by
Graeme: LEMON SHERBERT?
- Whenever the sherbert comes up, it's often mentioned that his grandmother sends him it. It's also described as "Not dangerous, but it turns him on".
- In Flight of the Conchords, Bret, after much fiddling around, accidentally takes a drug, leading to the lighthearted and whimsical "Prince of Parties" musical number.
- The X-Files
- Scully starts tripping after getting a tattoo with ergot-laced ink. It's not played for humor at all, as the guy who convinced her to get the tattoo has heard his talking to him for weeks, and it's driven him to kill his downstairs neighbor.
- There's also "Field Trip," where Mulder and Scully investigate the skeletons of two hikers found in a field. It turns out that the field is covered in mushrooms that trap those who step on them in vivid hallucinations while a Blob Monster under the field goes to work on digesting them.
- And Mulder goes on one in the 2016 miniseries episode "Babylon".
- Xena: Warrior Princess, "Altared States": Gabrielle eats some laced bread meant for Ikus. Hilarity Ensues.
- Parodied in Mystery Science Theater 3000: Pearl Forrester decides to test LSD on the robots and they hook them up to screens so we can see what they see. Servo sees everyone as monsters, but cheerfully says they always look like that to him. The only thing that's different for Crow is that the Milky Way bar Mike was holding suddenly turns into a Snickers, which causes him to freak out. Crow is also surprised to learn that Mike isn't a clown.
- Star Trek: Voyager has a variation when the Doctor programs himself with the ability to daydream, which soon gets out of control and causes him to switch rapidly between various fantasies. The most amusing parts are the other characters using the holodeck to see his daydreams themselves and as they simply watch his reactions to the different scenarios he's entering and leaving.
- 1000 Ways to Die features more than a few ways to die by way of mind-altering drugs. One particular death features a dope who eats mushrooms, trips balls, tries to join a furry orgy in the wilderness, and gets Eaten Alive by an angry bear. Another has some folks doing acid, with one of them trying to jump into a pool, only to break her spine on account of the pool having no water in it.
- The Dollhouse episode "Echoes" features the entire cast on one big tripout. The highlight of the whole thing is Topher desperately trying to stay lucid while explaining the situation to their dolls in the field on the phone, while in the background Adelle is jumping on a trampoline and shouts "Say hi for me!" just before he hangs up.
Adelle: ''I find lentils completely incomprehensible!"
- In one particular episode of the British series Midsomer Murders, straight-laced Chief Inspector Tom Barnaby tries some (special) brownies while interviewing a possible witness and subsequently comes over all giggly and walks along the top of an ornamental wall, all the while attracting confused looks from his Sergeant and the Coroner.
- The Farscape episode "Taking The Stone" features Crichton eating one out of a cluster of four magic mushrooms in exchange for a confession from the episode's villain: the twist is that while three of the mushrooms produce a dizzying high, one of them is lethal. Crichton manages to pick one of the safe mushrooms, thankfully, and spends the next minute doing a three stooges impersonation before passing out.
- One of the final episodes of Lexx, appropriately titled "Trip", half the crew consumed some mind-altering berry-like things that had been left as a gift, which led to some interesting hallucinations.
- One Life to Live played it in a way rarely seen in fiction; as Cole was going through withdrawal, he hallucinated his family and friends berating him for what a horrible person he was and how he ruined their lives. Basically the Intervention From Hell.
- In one episode of the short-lived Comedy Central show That's My Bush!, W accidentally takes two hits of Ecstasy, mistaking them for aspirin. Hilarity Ensues.
- In The Forgotten's "Train Jane", when Walter gets shot, the combination of panic and pain meds make him say wacky things.
Walter: Tell Candice I love her too, okay? But not in the creepy way. And tell Maxine, her blonde hair's like a lighthouse in the darkness, a love lighthouse.
(the doctor informs him that she's going to leave the bullet where it is for now)
Walter: No, no!! You gotta take it out, it's evidence! If you're not gonna, I will! Someone get me a scalpel, stat! I saw this on Animal Planet!
- In the Granada Television TV adaptations of Sherlock Holmes (starring Jeremy Brett as Holmes), the stories nearly always stayed very faithful to the original works. In "The Adventure of the Devil's Foot," Holmes deduces that several people have been murdered with an exotic poison unknown to British science. In order to be sure that the suspicious substance recovered from the scene of the crime is indeed the mysterious poison, he deliberately exposes himself to what he believes to be a small dose... According to the original story, terrifying hallucinations ensue. In the TV version, the hallucinations shown are actually not particularly terrifying, but Holmes is presumably experiencing far worse ones.
- Route 66 has an episode where Tod gets a drugged drink at a party by mistake. As is typical of the show, it's not played at all for comedy.
- How I Met Your Mother has a habit of replacing joints with sandwiches. Justified by the show's Framing Device: Future Ted is supposed to be telling the story to his kids, and so the bit with the drugs is replaced with something more G-rated.
- In "Blind Man's Bluff," an episode from the second season of The Sentinel, Blair eats a slice of pizza which, unbeknownst to him, is laced with "Golden". A short time later he's wielding a gun in the police garage, and...well...
Blair: You don't see them? They're coming through, through the walls and the floor, man.
Jim: Who are?
Blair: The Golden fire people. You don't see them, man? They're made out of fire and they're burnt. You think they're ashes, but they're alive, man. And we gotta send them back!
- In Due South:
Fraser Sr.: I'm dead. I don't dream. So I don't know what this sensation is that I've got. Although it's very similar to when Walter Singlefoot laced my tea with knik-knik, then seemed to turn into a twelve-foot alligator before my very eyes.
- In a memorable episode of Barney Miller, the detectives suffer interesting effects from munching a batch of brownies made by Wojo's current girlfriend.
Fish: The best I've felt in years and it's illegal!
- In The Closer episode "Smells Like Murder", Brenda's niece Charlie bakes a pan of special brownies, which Brenda later discovers. Brenda eats at least three, oblivious of their cannabis content. Hilarity Ensues. When Fritz finds out, he is not amused, and tells Charlie to start packing her bags.
- In an episode of Yes, Dear, Greg suffers from this in his desperation for nasal spray.
- People getting stoned on Fringe is fairly common, but the episode "Lysergic Acid Diethylamide" note has some brilliant moments where Peter and Broyles start tripping. They're even funnier when compared to Walter and Bellivia, who take their LSD (don't worry, it's for Mad Science) and don't react at all.
- 30 Rock
- Pierce descends into one complete with mocking animated skeletons in Community episode "Introduction to Statistics".
- After breaking both legs in a trampoline accident, Pierce becomes addicted to pain pills, popping them way after he's healed, and talking with a six-inch tall Andy Dick dressed like a pilot.
- While Pierce is painting Annie's apartment, the window ventilating the room shuts and the fumes get him hallucinating he's playing the piano flanked by two hula dancers,and he ends up making snow angels in the paint.
- Britta once shows up to the study room with frizzed hair full of various small items, ruined day-old makeup, and presumably a banana in her pants, and nonchalantly asks the group how long peyote lasts.
- Two and a Half Men - Charlie smokes pharmaceutical weed and sees hallucinations of various ex-girlfriends.
- Invoked verbally but averted in CSI season 12, in response to DB Russell's personal mushroom garden in his office. They are *not* hallucinogenic, but he's gotten at least one joke about it already.
Russell: Who killed Cock Robin? I, said the sparrow, with my bow and arrow. Who saw him die? I, said the fly, with my little eye...Brass: Those 'shrooms in your office aren't medicinal, are they?
- However, a hallucination-caused death happened at least once, it was the guy who got drunk on datura during a party in the desert and ended up dead and naked afterward.
- Dragnet had its share, naturally. Mostly LSD-related, since it was the '60s.
- In Dagvaktin, hallucinogenic mushrooms accidentally get mixed up with real mushrooms in the hotel staff's vegetable soup, with character-appropriate results. Georg dons a colander and builds a zealously-defended fortress out of food boxes, pot plants and cutlery; Gugga grabs her shotgun and goes hunting for imaginary crows in the guests' bedrooms, and Daníel strips naked and smothers himself in jam, insisting that 'wearing the jam takes away all my fears'.
- Red Dwarf features an after-the-fact example in the past bits of "Stasis Leak", past Rimmer is convinced that his future self's holographic head sticking out of the table is a hallucination (same with the captain in a chicken suit).
- In Person of Interest Finch, of all people, has one when a POI slips him some wine laced with Ecstacy.
- Done in Victorious when discussing how Trina got into Hollywood Arts. Turns out Sikowitz had drunk some bad Sri Lanka coconut milk he had gotten from a cousin (he had forgotten it got delivered at his back door and didn't pick it up for three weeks). As all the other judges were busy with other matters, he was the only one around. So when Trina started singing he was hallucinating her wearing wearing costumes and everything in technicolor. Sikowitz believed it was part of her performance and passed her audition.
- In the Law & Order: SVU episode "Wet", Olivia is accidentally dosed by standing over a pot of boiling mushrooms in a suspect's lab. This results in her ranting like a paranoid wacko and passing out.
- Murdoch Mysteries: One alcoholic drink served in a flask at the Alice in Wonderland costume party was drugged. Unfortunately, Detective Murdoch drinks it and Intoxication Ensues. He becomes belligerent which is very much out of his character. Later he experiences unsettling visions of falling down a hole, being too big to enter a door or the grinning Cheshire cat watching him. It turned out it was just a prank, not originally pulled on the Detective, but the consequences were very serious. Detective Murdoch was suspected of murder and he had to sacrifice a lot, both professionally and personally, to make things right.
- Mad Men, doing its 1960s setting right, has now had two of these: In season 5, Roger took LSD with his wife and some friends, and had hallucinations that included hearing an orchestra when he opened a liquor bottle, seeing Don in the mirror while Roger's hair was two colors, and witnessing the 1919 World Series from his bathtub. Said hallucinations proved eye-opening in that they made it clear his marriage to Jane was over. Season 6 had an even more blatant example with "The Crash", where the entire office took some kind of uppers. Though there were clear some hallucinations (like Don's flashbacks), much of the episode was left ambiguous as to what was really happening and what the characters were imagining. (The cripped Ken Cosgrove suddenly dancing out of nowhere?)
- Played for drama in Burn Notice in the season 7 episode "Psychological Warfare", where Michael is given a hallucinogen to encourage him to come clean about elements of his past. It works, but not well enough to blow his cover
- Being no stranger to comedic situations with extinct animals, the documentary Dinosaur Revolution had a Shunosaurus eating a few magic mushrooms. Then Hilarity Ensues when a a pair of Sinraptors chase him. He ends up killing one and the other one runs away.
- In Doc Martin Series 5, after noticing bouts of hyperactive behaviour, Martin fires his new receptionist for taking drugs. He later finds out that the "energy pills" her grandfather had given her were actually 70-year-old metamphetamines from his WWII ration kit. Both assumed they were safe because it had the Government stamp on, after all... the Government wouldn't give out something that was bad for you.
- An episode of Black Box has Dr. Black recommend a terminal cancer patient take a substance that's basically 'shrooms. She has a friend of hers who is studying the substance's effects on cancer patients give her a sample. Planning to return the rest to the researcher, she puts the unmarked bag in her purse. Her fiance is making coffee, discovers the bag, assumes it's cinnamon or something, and puts it into both of the cups. Just as Black is asked to explain to a girl why pot is bad, she herself starts seeing things (more than usual, given her own psychological condition). Her fiance starts seeing live animals in her fridge.
- In the Breaking Bad episode "Mandala", Jesse has his first shoot of heroin, and is seen levitating off of his bed as he gets high. All while The Platters' "Enchanted" plays in the background. (Aaron Paul, the guy who portrays Jesse, was lifted up in a rig and filmed.)
- On Shameless (US) Lip and Kev have great success selling marijuana in a college dorm but then Kev's supplier sells him synthetic marijuana which was laced with some unknown chemicals. Soon they have a room full of college students freaking out and having hallucinations. They manage to mostly contain it except for one guy who jumped out a window and broke his leg.
- On Vikings this takes a very dark turn when, after a battle, Rollo ingests some mushrooms and starts seeing things. He hacks off the leg of a Saxon prisoner because from where he was sitting the leg looked 'strange'.
- Elliot of Mr. Robot gets a long one in the third episode after taking some unidentified drug, featuring numerous scenes full of Foreshadowing and small metal keys.
- Hector Berlioz's Symphonie Fantasique has a scene in which the protagonist takes a large dose of opium to kill himself, he gets the dose wrong and proceeds to dream of watching his own execution after killing his love interest.
- Mitch Benn's "Tea Party" details the effects of various illicit substances administered (initially accidentally) to his unknowing aunty and uncle, with appropriate accompanying music for each new substance/verse.
- "5:15" from Quadrophenia documents the protagonist's drug-fueled train journey to Brighton.
- The man on the chessboard get up and tell you where you go and you've just had some kind of mushroom and your mind is moving low...
- This song chronicles the adventures of an LSD-addled Captain Kirk.
- "Picture yourself on a boat by a river...." Although John Lennon credibly Jossed the theory that the title of the song (which, for tropers living under a rock, is "Lucy in the Sky With Diamonds") is a drug reference (apparently, he liked the phrase, inspired by a drawing by his son Julian), there's little doubt that the actual lyrics have are inspired by Lennon's psychedelic experiences. (Marmalade skies? Kaleidoscope eyes? Rocking-horse people eating marshmallow pies? Plasticine porters with looking-glass ties?)
- Blonde on Blonde by Bob Dylan has Rainy day women. Dylan allegedly said he could`t record the opening track with sober people, so he fired up a round of joints... Thus, everyone on the take is stoned out of their mind, making the recording a literal mushroom samba. The hysterical laughter in the background should be proof enough. Everybody must get stoned indeed.
- One of the possible explanations for the plot to Job for a Cowboy's Sun Eater. If the protagonist isn't receiving visions from a bonafide seance, she's tripping balls on psychedelics (based on the nature of the visions and the album's flow itself, probably ayahuasca). "Worming Nightfall" is either where she gets trapped in a trip gone very wrong (if you believe it's drug-related) or in a dream world (if you believe it's supernatural). The band has intentionally left it ambiguous enough that both explanations are entirely plausible.
- The music video for "Learn to Fly" by the Foo Fighters depicts the results of a drug stash being kept in the reservoir of the coffee machine on a commercial airplane that the band is riding in, and then that coffee machine being used to brew coffee for the entire place without noticing said stash. Everyone on the crew gets high, along with nearly all the passengers (except for Our Intrepid Heroes, who declined the coffee) start to hallucinate wildly. It is left to the band members to take the plane in for a safe landing.
- An innocent children's song about gathering mushrooms in the countryside... or is it? Mangez-moi, mangez-moi, mangez-moi...
- In Pepe Deluxé's "Go Supersonic" music video, three guys each drink a "supersonic"-sized Hot Sauce coffee. They then hallucinate a strange go-cart race.
- Far Cry 3 has multiple interactive instances of this, induced by everything from hallucinogenic mushrooms, mystical potions, or just good old fashioned drugs.
- The moment that really stands out is the mission where Jason's sent to torch a bunch of marijuana plantations with a flamethrower. He starts getting a contact high from all the smoke and quite clearly having the time of his life; all the while, this music's blaring in the background.
- Continued in Far Cry 4, which has a mission where you get high on the fumes inside an opium factory, an entire questline based around a pair of stoners testing their new formulas on you, and a level where you are thrown into prison and drugged. Then you have to flee from hallucinatory demons.
- Yoshi's Island has an infamous level called "Touch Fuzzy, Get Dizzy." Touching one of the fuzzy monsters that float around in the area will cause Yoshi to stumble around like a drunkard for a minute, distorting the music and the game screen.
- Called "Lustiges Sporen Drama" in the German version.
- Stages 4-1 and 6-3 also have the Fuzzies, so be prepared for some Interface Screw in those stages, too.
- MFGG user gamester has made a series of fan games based on the above mentioned "Touch Fuzzy, Get Dizzy," featuring Mario, Toad, and Luigi, all feeling the effects of touching fuzzy (or, in Luigi's case, a fuzzy mushroom.)
- Well, hello there, Earthbound.
- A woman in Summers allows Ness to eat "Magic Cake", which allows Ness to have a vision of Poo.
- Being hit by a walking mushroom's blast can make a mushroom grow from your head, which randomly changes the direction keys. Also causes confusion in battle until removed by a guy... who eats it.
- To say nothing of the coffee a Mr. Saturn offers. Though really, speaking to your dad inside a Kaleidoscope is nowhere near as bizarre as... everything else in the entire game.
- What about Moonside? Or are we blaming that on the Mani Mani statue?
- MOTHER 3 continues the tradition:
Claus: Everyone's waiting, Lucas. Everyone's waiting to spit at you, throw rocks at you, and make your life Hell. Who's "everyone"?... everyone you love.
- When the party is forced to eat some strange mushrooms found in the jungle — in this case, it serves as a rather spiteful Journey to the Center of the Mind, as the hallucinogen preys on 'guilts and fears' (the party's dog is the only one not taken in). The events were apparently supposed to be even more horrible, but the creator decided to tone it down.
- Thankfully for poor Lucas, his next high — the return of the Saturns' coffee from the EarthBound — is much less horrific.
- NetHack has a hallucination status effect caused by (among other things) eating violet or yellow fungus, getting zapped by a black light, or drinking a potion of hallucination. It randomizes the appearance of every creature and item in the dungeon every time you take a step, and causes just about every in-game message to be rewritten in Surfer Dude speak.
- Z Angband has a similar effect. Monsters also receive new names so you don't know what your fighting — the names change every turn along with the appearance of the monster, and run along the lines of Cosmic Horror, Incredible Lovemaking Robot, and so on.
- WazHack, a graphical variant, makes the screen go a glowing, wavy yellow and every living or dead being except yourself looks like a random geometric shape. Also, the random messages on the walls, which normally look like illegible scribbling even though your character can read them just fine, change into graffiti which says "IS IT TRUE OR FALSE? YOU'RE NOW TOO FOOLISH TO KNOW FOR SURE."
- Punch Quest: Mutagenic Food causes rainbow colored wavy distorted images to appear.
- Jazz Jackrabbit 2 has an afro-wearing caterpillar enemy, resting on a toadstool (inspired by Alice in Wonderland) who blows out ring-shaped puffs of smoke. When the player hits one of these smokerings, the entire stage's colours start to cycle around psychedelically for a few moments, and the player's movement becomes distorted for a moment (Left is Right, etcetera).
- In the game Sprung, in Brett's story, a hippie character gets him to eat some mushrooms for a 'ceremony'. It leads him to hallucinate loud flashing colours, come up with bizarre game overs, and visualise the hippie as a cow. Slowbeef's Let's Play of the scene gives Brett some surreal No Fourth Wall dialogue during the scene, even cribbing lines from other Intoxication Ensues and Mind Screw scenes as homage.
- The entirety of Lockjaw The Overdose, a homebrew Tetris clone for Game Boy Advance.
- Allure Seeds in Pokémon Mystery Dungeon: Red/Blue Rescue Team and X-Eye Seeds in the sequel games had this effect- if the character eats one then all Pokémon in the room become
strange green doll-like thingsSubstitute dolls and all items, Wonder Tiles, and stairs turn into flowers until the effect wears off.
- The Fairy Ring in Quest for Glory I is comprised of Magic Mushrooms. Consuming them will cause the screen to change colors, with descriptions of the hallucinations ("Wow! Look at all the nice paisley horses! Not to mention the beautiful neon sky."). The first time you eat the mushrooms, you're warned not to repeat it. If you do, the hallucinations resume, and "your mind permanently warped, you die a garishly polka-dotted death."
- A very similar thing happens when you smoke Salim the Apothecary's hookah in Quest for Glory III
- Rise of the Triad had a mushroom-shaped "power up" that put you in Shrooms Mode, causing most items (including the bad guys, fired missiles, and spring pads) to have a pulsating glow and the player's view to rapidly shift up and down. One of the game's secret levels was a big room filled with nothing but shrooms and spring pads, leading to some whacked out bouncy fun.
- Fallout 3's expansion, "Point Lookout", features an encounter with a psychoactive fruit which explodes in the player's face... followed by having a lobotomy while the player character is hallucinating.
- To say nothing about Vault 106 in the base game, whose experiment was to pump hallucinatory drugs into the air system and observe how the occupants reacted; said reaction was to go insane and murder everyone else inside the vault. If the Lone Wanderer goes inside for a length of time, he starts to experience the effects firsthand, which manifest as unusual messages to himself on the computers and multiple illusions of his father and childhood friend.
- In the "Rite of Passage" quest from the Fallout: New Vegas DLC Honest Hearts, the Courier trips out on Datura tea, and has to fight a flaming Yao Guai ghost, which is just as deadly as its real brethren.
- The first Max Payne game has two levels like this, once when Mona knocks him out with some unidentified substance in a drink, and later when the Corrupt Corporate Executive Big Bad forcibly administers an overdose of V.
- In Grand Theft Auto III and Vice City, when you take the adrenaline pills everything becomes very slow and everyone speaks in low, distorted voices. Also, the player becomes super strong and fast. One mission in Vice City starts after you encounter a side character's boomshine. You have to drive him to the hospital while very, very drunk. Something similar happens in Grand Theft Auto: San Andreas, where you end up driving a van under the influence of weed after helping the van's owner torch an entire field of weed with a flamethrower. It happens yet again in ''Grand Theft Auto: Vice City Stories", when during one mission the protagonist is knocked unconscious with his face in a pile of cocaine, and has to complete the rest of the mission high after he wakes up.
- In Grand Theft Auto IV, the player character can also get drunk, with realistic driving impairment effects.
- Grand Theft Auto V also features several different sequences fueled by psychedelic drugs, including a hallucination of free-falling over Los Santos half-naked and mowing down wave after wave of evil clowns. There are also hidden peyote cacti that when ingested, causes the character to trip as an animal for a certain period of time, accompanied with a narrative from the character.
- In Deus Ex, you can make the main character smoke cigarettes, drink alcohol and even do drugs. The cigarettes make him cough and lose health. The booze actually increases health a little, but makes vision worse. The drug (called "Zyme") has no effect on health, but screws up your vision for a long time.
- A staple in the Saints Row series:
The Boss (Female Voice 1): It's like living inside a rainbow!
- In The Saints Row 2 mission "Bad Trip", the Boss is doped to the gills for a meeting with the Sons of Samedi, and has to survive the mission under the influence, which here means "with blurry and tilted vision". It's also possible to drink alcohol (same result as the drug from the above mission) and smoke blunts (screen is covered in fog) whenever you want, though taking more than two at a time tends to hinder the player character in addition to the Interface Screw (too many blunts causes the Boss to randomly stop and cough up smoke, for example).
- In the Saints Row: The Third mission "Pimps Up, Hos Down", the Boss is smuggled into Safeword (a BDSM club owned by the Morningstar gang) as a new sex worker, and ends up fighting their way through hordes of enemies alongside Zimos, all while drugged-up and buck-naked.
- Saints Row IV continues the proud tradition in Shaundi's Loyalty Mission: after scoring a new alien drug, the Boss and Shaundi (both of them) partake in it—and discover that it gave them actual superpowers. They proceed to complete the rest of the mission with their newfound powers while still tripping wildly (e.g. the Boss keeps seeing deadly enemies as colorful furries).
- Several of the mission maps are hallucinatory prisons for the gang members The Boss is trying to rescue, in any event. Kinzie Kenzington may very well try to kill The Boss if he ever described what she was stuck in. I'll never try it, so that's a maybe.
- In the World of Warcraft various alcoholic beverages (particularly during brewfest) can cause many different effects, from seeing pink elephants everywhere to seeing yourself swarmed by gnomes.
- In Donkey Kong Country Returns, DK and Diddy find a magic floating golden banana in the final level. After digging in, they find themselves in a mysterious land in the sky full of floating fruit platforms and koalas that are also half helicopter. One might argue that this wasn't a hallucination and they were actually transported to a land where giant cherries are actually proximity bombs. One might also be a little naive.
- Golden Sun: Dark Dawn includes an entire psychedelic dungeon, the "Phantasmal Bog", that is reached by having a collective bad trip on Dream Leaf harvested from a sickly tree. Once the tree is healthy, you can buy some Dream Leaf to use in the closed-up Border Town, causing a hallucination that the town is open, allowing you to reach a summon tablet that is otherwise completely inaccessible.
- The Lord of the Rings Online has at least two examples of this trope:
- In the Water Works area, there are some giant toads who produce secretions that cause the player's character to have "hallucinations," wherein the screen colors change and there are other visual effects. And you don't even have to lick the toads. (In addition, the mouseover text for the debuff icon says something like "You can taste rectangles and smell the color magenta.")
- One of the quests in Evendim involves sneaking a mixture into some giants' cookpot, after which they start hallucinating that millions of spiders are coming out of the woods.
- Bug! Too! has the final stages of the game, Cicada Night Fever. The entire level is one hell of an acid trip- the platforms are unnaturally colourful, the background contains Dali's clocks, you fight toads (from the first game) and floating Cheshire Cats, and the Final Boss? Three of that smoking caterpillar from Alice in Wonderland... while deadly popcorn rains down from the sky.
- Aquaria features the Rainbow Mushroom...which doesn't do anything on it's own, but mixed into Hot Soup it makes Rainbow Soup, whose effect is listed as "trippy". What this gets you is the same Interface Screw animation as a faceful of squid ink, but in rainbow colors. For about thirty seconds, anyway; after that the colors darken almost to black as Naija experiences the crash that almost never comes with this trope, letting out pained gasps at an alarming rate until the soup wears off after another thirty seconds or so.
- In Hatoful Boyfriend, Anghel Higure has a condition causing his body to produce hallucinogenic pheremones... to which he is himself not immune. His Cloud Cuckoo Lander behavior is because he is on a permanent acid trip. ...though it's also hinted that there is more to it.
- In stage 3 of Lollipop Chainsaw, a local farm is taken over by a psychadelia-themed Dark Purveyor. Juliet will occasionally run across a giant mushroom that she needs to cut down to progress, and each time it triggers a trippy battle against a giant zombie chicken monster, followed by a minigame where you run over zombies with a combine while Dead or Alive's "You Spin Me 'Round" plays. Then after you beat the boss, you find out the whole stage was just a hallucination caused by the boss's powers.
- While the Kid in Bastion doesn't really take anything, wandering around in Jawson Bog (which the Kid is warned about before hand that "That place'll eat your mind") eventually causes him to start having some rather disturbing hallucinations (including the narrator Rucks sounding more unhinged and hostile,) hinting at the Kid suffering from Survivor's Guilt.
- Blood had delirium shrooms, which showed up in the beta versions, but were never used in the final game(though some user-made level packs, such as Bloody Pulp Fiction use them). They caused the camera to wobble and sound to distort for a few seconds, rendering the game almost unplayable.
- Touhou canon itself has suggested that the magic mushrooms Marisa gathers from the Forest of Magic to power her spells are, in fact, "magic" mushrooms. Or possibly both.
- Many Roguelikes have hallucinogenic potions.
- Ultima Underworld I-II and Ultima VIII have edible trippy mushrooms.
- Not even Mario & Luigi: Dream Team was immune to this trope. The "magic water spring" creates this which leads into a faked game over. It heals you as well for some reason...
- Knytt Stories has Don't Eat the Mushroom, played by ProtonJon. Here's the link.
- Which also spun off countless imitators.
- Makoto's gag reel in BlazBlue: Chrono Phantasma essentially amounts to this when she receives candy from Kokonoe, which she shares with Taokaka and Valkenhayn. Allegedly, it's supposed to awaken the inner beast, but somewhere along the line Taokaka pulls Makoto's tail off... and then the severed tail somehow comes to life! Can you make shit like this up sober?
- In (the already trippy) Hotline Miami 2: Wrong Number, the Son gets one of these after he has a bit too much of his own product. In it, he slaughters both the Fans — in the form of hallucinations of animals of the masks they wear — and his own henchmen before walking off the edge of a building, seeing a rainbow bridge to Heaven.
- In We Happy Few, the town of Wellington Wells looks very different if you've been taking your Joy. This is made especially clear in the game's prologue, where the "piñata" the player character's co-workers are pummeling turns out to be a dead rat. And then they devour its putrid flesh with every sign of enjoyment.
- Mentioned in Mass Effect 2 if a female Shepard romances Thane: if you talk with Mordin, he'll tell you that drell skin secretions have a hallucinogenic effect on humans and warn you not to, um, swallow.
- Subverted in Mass Effect 3's Citadel DLC. This is only what the casino guard thinks is the case when Javik claims to have met the guard's ancestors while they were living in caves and throwing rocks at wildlife.
- Batman: Arkham Series
- In Batman: Arkham Asylum: Batman wanders into three areas where Scarecrow is present and comes under effect of his fear toxin which starts changing the landscape before thrusting Batman in a nightmare world where he has to avoid the gaze of a giant Scarecrow and reach bat-signals to drive him off. The first two times Batman snaps out of it, he's in different areas meaning he somehow made his way to them through the hallucinations. The third showing it happens as a Mind Screw to the players by having the game lock up and suddenly restarting to the intro sequence.
- Batman: Arkham City: When Batman takes the League of Assassin's trials by drinking some of the Lazarus Pit, the liquid's effect has him suddenly in a desert like landscape where he has to follow Ra Al Ghul and fight several clones of him before he can pass. The battle against Ra also takes place in the same landscape for some reason. Also while not drug related, the side mission with The Mad Hatter has undertones of this via his mind control mask.
- Batman: Arkham Origins: Again the Mad Hatter side mission, which is longer this time has you traversing a rather whack out version of Wonderland while trying to track him due to some hypnotic device.
- Batman: Arkham Knight, as Scarecrow is the main Big Bad of the story, this pops up a few times such as in the intro sequence where he tests a new fear toxin on a diner causing everyone to hallucinate seeing zombies attacking them. Batman gets spray with the toxin a few times, causing him to see Joker for the rest of the game as well as what he thinks is Barbara/Oracle's death in the middle of it as well as a few mind screw sequences such as battling dozens of Jokers where he's eventually forced to confront breaking his one rule: killing someone.
- In Dragon Age: Inquisition, Blackwall mentions a previous assignment where he and his team lost all of their food to a flash flood. All that left them with were the berries that the newest member of the group had found. For the next two days, Blackwall thought he was surrounded by a ring of nugs that were singing sea shanties.
- In Lisa, Joy is said to have hallucinatory effects, Allowing the user to feel nothing while driving the user to search out the thing they desire most. Brad often has flash backs and sees hallucinations throughout the game and is even hinted to have severe effects on his motives and psyche.
- In Pillars of Eternity, Zahua's personal quest has him and the rest of your party partaking of his stash so you can join him on a Vision Quest.
- In Stardew Valley after the local wizard gives the player character a dose of his brew to make them "one with the forest," dancing leaves and pine trees appear on the screen for a few seconds.
- Retro City Rampage has a milk bar that gets the player drunk and makes the screen wavy, and a merchant dealing in actual mushrooms with various effects.
- In Scary Go Round, Shelley gets high on berry jam at the Tackleford Fair.
- The "Mushroom Samba" bit is taken literally in this Loserz strip. (A bit NSFW.)
- El Goonish Shive: Supposedly, Grace and her catnip.
- Whenever Sandusky or Kashmir do catnip in Sandusky.
- Subverted in Jin Wicked's Crap I Drew on My Lunch Break:
"But this is just herbal tea..."
"I know, I just wanted to draw all this cool stuff."
- The blue mushrooms of College Roomies from Hell!!! have this effect. Merely touching them can cause you to see tiny windows on them, with Smurfs inside.
- Bob and George: Mega Man goes on a trip after being attacked by Needle Man in which he encounters a spirit guide in the form of a yet to be created communist robot whom he proceeds to throw at the monstrous apparation of Needle Man in order to to defeat him. George later gets his own spirit guide in the form of X, when he finds himself hanging up in Wily's lab again and Wily dopes him to the eyebrows just to get him to shut up.
- Liquid Snake and Decoy Octopus of The Last Days of FOXHOUND decided to try some of Vulcan Raven's "medicine" to see if they can see the future... this happens.
- Nodwick has a strip where the evil undead anti-paladin Count Repugsive ends up tripping on too much cough syrup. Don't ask us why the undead need to drink cold syrup.
- It's because of their coffin.
- What Birds Know uses this metaphorically, if not literally (it's somewhat ambiguous in the story itself), when the female protagonists enter an Alternate Universe where they experience bizarre hallucinations and... lay golden eggs.
- Tai from Questionable Content apparently enjoys LSD from time to time. At work.
- Ivy from Bobwhite snacks on some chips whose label warns, "High in cholesterol. May cause vivid fever-dreams." She then hallucinates a visit from Bootsy Collins.
- +EV: So, Harold owes the Goombas hundred dimes, and they'll kill him if he can't pay?
- Sweet Bro and Hella Jeff: SUDDENLY WEED DREAMS◊.
- In Sinfest, Squigley on mushrooms. (At this point in the strip. Earlier he had smoked weed and just been lethargic; later, he will have shamanistic powers and actually fly from taking drugs.)
- In Rhapsodies Hrenvuha (a kind of horseradish vodka) has that effect.
- Homestuck has Act 6: Act 5: Act 2, in which Jane licks a giant magical lollipop, turns into a technicolor, creepily smiling version of herself. She then proceeds to turn all her friends into smiling technicolor versions (However, Dirk isn't affected, despite him turning technicolor), form a sex cult, dance around a poorly rendered JPEG Christmas Tree to the sound of Jingle Bells as played on bicycle horns interspersed by random sound effects, forge legendary garishly colored artifacts, and then flood the world with garishly colored fancy porcelain Santa figurines. Even the narrator compares the magical lollipop to drugs.
Let us never speak of ACT 6 ACT 5 ACT 2 again.
- Girl Genius has a gas concoction that Master Payne's Circus of Adventure cooked up that they use to extricate Agatha and themselves from a brutal fight with Wulfenbach forces, simply by spreading it around and yelling "The Heterodyne Boys are here!"
- Not to mention the effects of drinking coffee brewed by a Spark-created machine.
- In the Third Night of The Tale Of Gaven Morren, Gaven is dosed with Elisdee Lily extract. Given that everything is out to get him already, and you can see how not being able to tell what's a hallucination from reality might be a problem. The hallucinations manifest as frequent daydream surprises, the inability to recognize himself in mirrors, and even hallucinating the presence of an entire character.
- Domo Gets a Brainfreeze
- James Brown of Survival of the Fittest says hi, he'll get back to you right after the Boos stop chasing him (a.k.a. epic acid trip).
- We Are Our Avatars: The Group ate some strange fish and had strange reactions for a while.
- AMV Hell presents its own interpretation of Paprika.
- As seen on Texts From Last Night:
(828): I can't remember where my feet are. All I can see are colors, and all I can feel is terror. The lollipop was a bad idea.
- Aitor Molina Vs: A literal one happens when Aitor Molina eats a mushroom on A Mvs Seahorse Seashell Party. Most of the clips are taken from Beavis And Butthead Do America.
- In the episode "Happy Birthday" of Idiotsitter, Gene and Chet make Billie a peyote-laced birthday cake, leading to hallucinations and other drugged-out behavior for most of the episode.
- Beavis and Butt-Head: Excessive caffeine or sugar was enough to turn Beavis into his psychotic alter ego "The Great Cornholio". Likewise, see The Movie above.
- In the episode "Raisin The Stakes" on Clone High, an anti-drug speaker tricks the entire high school into believing that raisins are a hallucinogen. Many drug montages take place of varying degrees of weirdness. (The entire episode is a rock opera ripped off from The Wall and Joseph and the Amazing Technicolor Dreamcoat with traces of Godspell and Hair - very 60's-70's.)
- The Simpsons:
Homer: Man, this is crazy. I hope I didn't brain my damage.
- "El Viaje Misterioso de Nuestro Homer (The Mysterious Voyage of Homer)": After eating some of "the Merciless Peppers of Quetzlzacatenango" at a chili cookoff, Homer starts hallucinating wildly (which Marge mistakes for Homer breaking his promise about getting drunk) and goes on a journey to find his soulmate.
Chief Wiggum: "The merciless peppers of Quetzalzacatenango! Grown deep in the jungle primeval by the inmates of a Guatemalan insane asylum."
- One of the comics set during the same episode, but instead following Chief Wiggum has this happen to him as well, causing him to, among other things, go on a rampage through town, envision a statue as a giant criminal, and see a spirit animal whom he then spends several hours asking what The Matrix was all about.
Otto: Don't worry, I won't hurt you. I only want you to have some fun.
- In "Worst Episode Ever", Homer eats a box of ancient bicarbonate of soda (baking soda) ("I think it came with the house," comments Marge) on a dare from Bart, which causes him to have an "antacid trip" (and Bart to win $50).
- In "D'oh In the Wind", where Homer becomes a hippie, Flanders starts seeing Grateful Dead-type bears, Pink Floyd's Marching Hammers and Rolling Stones-type lips after drinking carrot juice laced with peyote. Barney sees a fanged monstrosity from the same drink, but is quickly saved by a beer and his friend Pinky, the pink elephant, Grampa and Jasper begin giggling like Beavis and Butt-Head (while sitting on a park bench in the same manner as Beavis and Butt-Head on their couch) and Willy sees a beautiful woman whom he starts kissing (which is actually a rake and the kissing is actually Groundskeeper Willy scraping his face with the tines of the rake).
- In "Homer Loves Flanders," Homer comments that Shelbyville threatened to spike Springfield's water supply after Springfield burned down their city hall, but they didn't have the guts. Cut to Marge drinking some water in the kitchen. Sitar music suddenly plays and Marge comments that the walls are melting again. A cooked turkey pops out of the oven and flies away.
- In "Selma's Choice", Bart dares Lisa to drink some of the "water" from a boat ride at Duff Gardens (which is so polluted, it doesn't really look like water anymore- either that or said water is actually beer). Once she does, she starts to hallucinate (starting with the Dutch dolls on the "Little Land of Duff" ride receding down a dark, endless hallway), becomes paranoid after seeing a monster grow from Selma's arm, tries to whack Bart and Aunt Selma with a boat oar, stumbles around the Duff Lite Parade commenting on how she can "see the music," and is found hours later after security saw her swimming naked in the Fermentarium, clad in only a towel and declaring herself, "The Lizard Queen."
- In "Weekend at Burnsie's", when Homer starts smoking medicinal weed, he opens his bathroom's door with a 60's-style happy face, grabs a razor with a happy face, sees rainbows coming out of his beard, and then he gets on his car (with a happy face too!), under a pink sky and the smiling sun, his car takes off, and he drives away — all with Donovan's "Wear Your Love Like Heaven" playing.
- There was also a subversion: in "Missionary Impossible", where Homer becomes a missionary, he starts licking hallucinogenic toads out of sheer boredom; however, the only thing we can see is his dilated pupils and his unusual reactions.
- In "I'm Goin' to Praiseland", where Ned opens a Christian theme park. He erects a statue of his late wife (the park was a lifelong dream of hers), and people who stand in front of it are hit with a vision of their idea of heaven, while onlookers see them writhing on the ground speaking in tongues. Everyone thinks it's something truly spiritual, until Ned discovers a gas leak near the statue and that people were just "getting goofy off the gas fumes."
- In "Boy Scoutz 'N The Hood" where Bart finds a twenty-dollar bill. He and Milhouse buy an "all-syrup Squishee," which causes them to behave drunk out of a extreme sugar rush and also causes the show to segue into one of the most memorable songs of the series. And towards the end of the song, it causes the boys to hallucinate. In reality, they end up joining the Junior Campers.
- Also, in the episode "Homerpalooza" Otto hallucinates that his shoes are talking to him.
- In "Bart Gets an Elephant", after sniffing some ammonia fumes Homer hallucinates that the cleaning mascots come to life and start dancing around causing him to laugh. Suddenly they spring out and attack him causing him to scream, Marge hears this and tells him to stop screaming so loud.
- In "Team Homer", Mr. Burns sees Homer as the Pillsbury Dough-boy while under the influence of ether, and since he's a big fan of his Homer uses this to get money for his bowling team from Mr. Burns. Burns then sees Hans Moleman as Lucky the Leprechaun, and tries to kill him and steal his brain to figure out the secret of his Lucky Charms.
- In "King of the Hill", when Homer is climbing the Murderhorn mountain, he starts feeling light-headed from the thinning atmosphere, then eventually says "Why should I climb when I can just take the escalator?" He then hallucinates that he's riding up the mountain on an escalator dressed in a suit and top hat, then leaping from peak to peak on the back of a blue mountain goat, then getting an elevator ride from the Abominable Snow-Monster from Rudolph the Red-Nose Reindeer. Back in reality, he's actually tumbling down the mountain all cut up with a big smile on his face.
- In "Last Exit To Springfield" Lisa under the influence of laughing gas hallucinates that she is flying through the air and comes across a parody of Pepperland from Yellow Submarine and meets The Beatles in a purple submarine.
- In "Married to the Blob", Homer and Mr. Nakamura get drunk on potent rice wine and have a Hayao Miyazaki-inspired hallucination.
- "Hell Is Other Robots" has Bender "abusing electricity", which is apparently that universe's robot-drug. Not only is it very addictive, but the first time he takes a hit he has a wonderful but brief hallucinatory trip.
- Also, in the episode "The Farnsworth Parabox", the crew vists Universe 420, a universe where everyone is on drugs. We don't get to explicitly see anything there, but the main-story of the episode is mind-trippy enough in its own right. As Fry says about the situation: "It's like that drug trip I saw in that movie while I was on that drug trip."
- Almost the entirety of the episode of The Sting, combined with All Just a Dream. It's revealed in the end that the majority of the episode was Leela's dream while she was in a coma after getting a dose of venom on the bee's stinger that scratched her..
- Celebrity Deathmatch; when an accident sends Nick into a coma, he has a bizarre morphine-fueled dream of Elvis Presley and Jerry Garcia fighting in the Deathmatch ring to the tune of the song "Kung Fu Fighting".
- In the Rocko's Modern Life Halloween episode "Sugar Frosted Frights", Filburt eats Halloween candy for the first time and enters a sugar-rush-induced fantasy inspired by the "Night on Bald Mountain" segment from Fantasia.
- Hi Hi Puffy AmiYumi, "Rock and Roe": After eating too much sushi at a cheap seafood restaurant, Ami and Yumi start hallucinating.
- Jason from Home Movies indulges in too much candy at Fenton's birthday party and begins behaving like a combative drunk. A concerned Melissa calls a cab for him.
- Avatar: The Last Airbender
- The entirety of the episode "Nightmares and Daydreams". Note to people with no knowledge of why one should not stay up for three days: sleep deprivation makes your brain self-produce DMT. The dreams that cause the sleep deprivation are pretty weird as well (Aang with a Badass Longcoat and Anime Hair?). The crazy comes to a head when Aang imagines that Momo, a tiny Team Pet, is talking to him. This is followed by Appa, who is a giant, six-legged bison, talking along with the other characters as if it's perfectly normal, to the point where Aang doesn't notice. After Momo and Appa suddenly don Samurai garb and start fighting with swords, Aang declares his desire to dive under a cold waterfall.
- There's also Sokka and Momo's infamous trip from "The Desert", where they drink some cactus juice in order to quench their thirst while wandering around in the heat. The problem? The cactus was poisonous and had something in it (probably mescaline), causing them to hallucinate and cause them to act just a little off-kilter.
- Toot, Wooldor and Xandir have one of these moments in Drawn Together by licking Ling-Ling repeatedly. They try several things to make him "dis-ap-poin-ted", but eventually get bored and simply pass him back and forth. All three of them truly freak out when Ling-Ling's bodily secretions dry up.
- In the second half of "Lost in Parking Space" Toot drinks the saltwater from a fish tank and claims she sees a polar bear with a scorpion tail. It turns out true later on.
- Teen Titans
- The episode "Haunted" features a very unfunny example. Robin accidentally inhales an unnamed hallucinogen from an old mask of Slade's. Unlike most examples, however, this Mushroom Samba leads to what most fans consider the darkest episode of the series — Robin hallucinates that Slade is everywhere and goes on a rampage trying to stop him, even going so far as physically hurting Starfire (his best friend and love interest) and threatening to "take down" his team if they try restraining him. The drug manifests every blow on his body as though he really is battling someone, and so before he realizes that bright light disperses the visions, he's nearly beaten to death... by himself. The Titans are convinced Robin has gone insane until Raven mind-links with him and gets a punch in the face by Slade herself.
- A less scary but still somewhat serious example: in "Crash", Cyborg gets his turn when Beast Boy accidentally gives him a computer virus. He then rampages crazily through town and eats everything in sight, while having strange food-related hallucinations.
Cyborg: (tearing apart an ATM) You can keep your sprinkles, I need raspberry filling!
(he punches the machine, which causes a bunch of dollar bills to spill out into his mouth; he spits them out)
Cyborg: No! Not macaroni!
- At one point, the team approaches him cautiously, and he sees them as giant eggs!
Starfire: You remember who we are, yes?
Cyborg: You're the nasty egg people who stole all my waffles!
- At one point, the team approaches him cautiously, and he sees them as giant eggs!
- South Park
- The episode "Major Boobage" had Kenny getting high off cat urine and tripping out into a Heavy Metal-style hallucination where there are breasts everywhere (even in the architecture!) Kyle's dad later takes a hit of cat pee, culminating in the two duking it out half-naked in a sandbox. At the end of the episode Kenny gets high on a bunch of flowers.
- All the boys (including Jimmy, Butters, and Token) take hits of cough syrup in "Quest for Ratings," assuming that the wild hallucinations are bound to give them plenty of ideas to improve their show. They certainly have fun with the hallucinations, but the only "ideas" they emerge with are some squiggly lines and a circle drawn by Cartman and the Happy Days theme song as written by Kyle.
- In the Angry Beavers episode "Up All Night II" the eponymous beavers both suffer from lack of sleep. Hilarity Ensues as the two beavers begin talking weirdly, acting weirdly and eventually even hallucinate the more and more their rational thinking starts to suffer due to lack of sleep. The episode's even more hilarious if you watch it while you are tired yourself.
- No surprise, but Family Guy has one too. A result of Peter and Lois smoking weed (again, as it turns out) to find inspiration to write a song for a contest. They end up licking Chris thinking he's a sundae in a magical world made of desserts and candies, lying naked on the couch together (on the FOX and syndicated version, the two are in their underwear), and thinking they sang beautifully during the talent show (when, according to Chris, they were so baked, that they thought their off-key screaming was beautiful music).
- One occurs in "Seahorse Seashell Party" when Brian suffers nasty hallucinations after eating some bad psychedelic mushrooms.
- In the Phineas and Ferb episode "The Ballad of Badbeard", Candace starts hallucinating wildly thanks to some weird moss. She ends up following Perry on one of his missions, all along thinking she's just dreaming the whole thing.
"Why do my nostrils whisper to me..?"
- During Don Hertzfeldt's "Intermission: In the Third Dimension!" sequence of The Animation Show, one of his signature cloud characters dons 3D glasses, and hallucinates in 3D! (A theoretical realm of space and time; where the laws of physics are meaningless!)
- Similar to the Real Life example below, in Star Wars: Clone Wars, Anakin Skywalker gets a blast of steam in the face in a cave on Nelvaan. As a result, he starts seeing the cave paintings move. Considering how well the vision summarizes and foreshadows his own fall to the Dark Side, The Force probably assisted the lack of oxygen.
This sequence parallels Luke's experience in the cave in Episode V, where he receives a similar vision/warning about his own susceptability to the Dark Side. Not counting his fall(s) in the Expanded Universe, Luke would seem to have payed more attention to this warning.
- This has happened a couple of times in King of the Hill.
- In "Hillenium," Hank accidentally inhales some varnish while working on a grandfather clock (Hank should have known better than to close the garage door when working with chemicals that can cause hallucinations and brain damage when used frequently and in a closed space) and he hallucinates that he, his family members, and his hero Tom Landry are mechanical moles in a whack-a-mole game.
- In "To Kill a Ladybird" although we don't see his point of view Dale under the influence of wild mushrooms describes cartoon characters dancing around his head when he closes his eyes, that harmless animals are out to kill him, and that Hank is spewing bugs from his mouth.
- In "The Son Also Roses," the two stoners hallucinate that Hank has an enormous head, many mouths, and has a distorted voice.
- We even saw a pig's hallucination in the episode "Lost in MySpace"
- Though not exactly a cause of drugs, one episode of My Life as a Teenage Robot had Jenny getting a dream chip installed so she can experience dreams. She starts to abuse it however and uses it during the daytime allowing her to see some pretty trippy stuff (all of her dreams are done in a different animation style). Things come to a head though when the chip gets damaged and she see everything in a Dr. Seuss style and goes on a rampage believing the people are Greek monsters.
- Inspector Gadget: "NSF Gadget" involves hallucinogenic "crazy gas" being placed into the oxygen supplies of astronauts, causing them to see visions of space monsters, and one of Gadget's hallucinations involves gigantic literal mushrooms.
- Space Ghost Coast to Coast: "Flipmode" involves Space Ghost interviewing Busta Rhymes (who laughs at nothing in particular for most of the episode) and breaking open natural gas pipes. This leads to mostly-unseen hallucinations and freak-outs by the entire cast.
Space Ghost: DIVE! DIVE! SUCK ON THE PIPES!
- Daria: "The Teachings of Don Jake" has the Morgendorffer family (except Daria) losing their marbles on a camping trip by eating psychotropic berries (which Quinn calls "glitter berries"). They'd probably still be chasing the spirit animal if Helen hadn't brought her cell phone...
- In the American Dad! episode "The Magnificent Steven" Stan buys Steve and his friends a small herd of cattle in an attempt to toughen them up, little does he know the cows are infected with Mad Cow Disease, during the course of events he make them slaughter the calf and only he eats the meat which causes him to hallucinate that owls are out to steal his meat (we don't see this), then he takes them to an alley where he hallucinates that he is in a bright more cartoony world and sings a Western song with a jack rabbit and prairie dog. We then cut to reality and he's dancing in his underwear with a beer pack and burger wrapper, he then orders them to cross a river which is actually a busy highway, and they end up having to save him from this. In real life he would've eventually died.
- In the episode "In Country...Club" after eating a rare bird Roger hallucinates that he's flying in a brightly colored CGI world with constantly changing shapes and floating in front of a singing gargoyle.
- In "100 A.D." after Roger puts some amphetamine droplets in his eyes and eats some expired cheese puffs he hallucinates that Klaus is Garfield in a bowl and Steve is a walrus in a Nazi uniform.
- The Venture Bros. - Hank accidentally pokes himself with a drug-tipped shoe spike of Molotov Cocktease's, and starts hallucinating, finally attacking his dad with a papier-mache sword.
- Regular Show has one of these in "Weekend at Benson's" as the result of Mordecai, Rigby, and Benson drinking a super-spicy concoction known as "Mississippi Queen". The song of the same name even plays during the hallucinations.
- In the Gravity Falls episode "The Inconveniencing", Mabel eats bleventeen packets of a strange German confection called Smile Dip, which apparently got banned in America sometime shortly before the abandoned convenience store it was found in got, well, abandoned. It's never mentioned why the stuff is banned, but it's probably because it's capable of inducing vivid hallucinations (as she soon discovers). She spends much of the episode lying on the floor with her pupils dilated, hallucinating wildly and mostly unaware of what's going on around her.note
"The future... is in the past! Onwards, Aoshima!"
- In the Scooby-Doo! Mystery Incorporated episode "Night Terrors", the gang stays at a mansion, and starts seeing terrifying hallucinations (also, Daphne sees Shaggy as Fred and kisses him). It turns out that the firewood the mansion was using was Terror Wood, which releases hallucinogenic chemicals into the air when burned.
- The Terras cause this to happen to the Burners on Halloween in Motorcity. They release a special gas that forces them to see their biggest fears: comedic ones for Texas and Claire giant candy and being married to Chuck, respectively; serious ones for Mike and Julie his past working for Kane and her father finding out she's a Burner.
- Penny from Littlest Pet Shop (2012) has one of these when she eats too many sweets. Her friends, equally high on sugar, show other characteristic signs of being on drugs.
- Bob's Burgers - while cooking Thanksgiving dinner with his family posing as his boss's family, Bob gets drunk on absinthe and has a glorious hallucinatory vision of a perfect holiday riffing off My Neighbor Totoro. Another episode has him popping pain pills for carpal tunnel brought on by excessive videogame playing. He sees the bullies of his young mentor as characters in the 8-bit game and furiously chases after them.
- In the first episode of Star vs. the Forces of Evil, Star defeats Ludo's minion Buff-Frog by stunning him with a "Jellybean Hallucination Mist".
Buff-Frog: I'm freaking out!
- In the episode "Goblin Dogs", when Star, Marco and Pony Head finally eat the titular food, they're initially underwhelmed, thinking they're just ordinary hot dogs. Then they all experience a trippy rainbow-colored vision and agree that they they are the best hot dogs in the universe after all.
- Veggietales In The House: In "Bob and Larry: Gettin' Angry", Bob and Larry refuse to fall asleep...which winds up resulting in them seeing some rather strange things, like Jimmy Gourd walking across the ceiling and tiny versions of themselves dancing on each other....and that's not even getting into the Disney Acid Sequence that follows shortly afterward.
- Truth in Television, possibly: Some scholars of Greek literature believe that the Ancient Greek Oracles obtained their visions and heard the voices of the gods because they inhaled steam from natural geothermal vents for hours every day.
- Certain groups of people who are around even to this day owe their mythologies and legends to such experiences since they believed certain plants and substances had spiritual powers which could be tapped by eating or smoking them. As for who, well, it's probably better not to list them here.
- The hallucinogenic properties of lysergic acid diethylamide (better known as LSD or acid) were discovered by accident by research chemist Albert Hoffman when he unknowingly ingested some that he came in contact with. Hoffman realized that he had made a significant discovery, and so three days later he deliberately took 250 micrograms of the drug, which he estimated would be a minuscule threshold dose. He was wrong — the actual threshold is one tenth of that amount. Dr. Hoffman spent several hours terrified that he was possessed by a demon, that his next-door neighbour was a witch, and that that his furniture was threatening him, before relaxing into pleasant hallucinations of kaleidoscopic images in which every sound he heard became visible.
- Dock Ellis pitched a no-hitter on June 12, 1970 for the Pittsburgh Pirates while under the influence of LSD. He later spoke of the whole event, to which this video skillfully animates.
- Ergot, a fungus which grows on some types of grain during wet winters... and is apparently not destroyed when baked into bread along with the rye, can have hallucinogenic effects (along with gangrene and/or dying). Ergot contains ergotamine, a precursor to LSD. Some scholars believe that those who testified at the infamous Salem Witch Trials and similar events in Europe as having witnessed "witchcraft" and the Devil, had in fact been the result of a combination of religious fervor (i.e. they already believed demons and witches were everywhere)... and hallucinating due to eating ergot-infected rye bread. It should be noted that Albert Hoffman was in fact researching ergot when he discovered LSD.
- Ergotism is also suspected to be the cause of the dancing plague, a series of accidental medieval raves.
- This could also be the reason madness was believed to be infectious in medieval days due to an ergot infestation in a town's bread supply.
- Bill Hicks frequently talked about taking mushrooms in his stand-up routines, and referred to their effects as "squeegeeing his third eye".
- Psychopharmacology posits that hallucinogenic substance predates history, which is supported by its common prevalence among existing tribal societies today. These tribes also use them for religious/revelatory applications, and some of more radical psychopharmacologists (I'm looking at you, Terrance McKenna, and God bless you,) "theorize" that our evolution into higher order thinkers was due to revelation brought on by hallucinatory and psychoactive substances.
- This can even happen without drugs, namely with high fever and sleep deprivation. And epilepsy. And comas. And semi-regular, nightly unconsciousness.
- Hypnagogic and hypnopompic hallucinations are where people have various sorts of hallucinations (most commonly seeing spiders) while falling asleep or waking up, respectively.
- In the 1970s, cops raiding an LSD factory in Wales failed to take into account that it had been making the stuff in large quantities for some time. The carpets, curtains, easy chairs etc. contained a significant quantity of spilled powder. They conducted a thorough search. Enough said...
- Both the British and American army's have experimented with LSD.