Power Nullifier

Gerrard: But it doesn't do anything!
Hanna: No—it does nothing.

A super-power or Applied Phlebotinum device that "turns off" either all super-powers or those from a certain Meta Origin. Can also be referred to as a "power neutralizer".

This can be temporary or permanent; the temporary version is generally used as either part of a Brought Down to Normal plot or as a plot device to enable villains who normally wouldn't stand a chance against the heroes, while the permanent Depowering version is usually a way to threaten someone without trying to kill them. Tailor Made Prisons for super villains usually incorporate one into the design.

Curiously, very few people who say I Just Want to Be Normal create a modified version of these for their own personal use, even if the technology seems to be relatively available. Even worse, if a hero is Blessed with Suck, not even the smartest scientists allied with the side of Good seem able to invent a safe one.

Related to Powers as Programs. For countering the products of those powers, see Anti-Magic. If the power has already been used, Dispel Magic can remove the effects. Power Limiter is a weaker version. No Sell is when a character ignores, not nullifies, another's powers. Mage Killers often weaponize this ability, as they do with Anti-Magic. See also the Kryptonite-Proof Suit, which can be used to resist Weaksauce Weaknesses.


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    Anime & Manga 
  • In Bleach: While it oddly never gets mentioned anymore, there's a type of stone in Bleach in the Soul Society that can greatly weaken spiritual power called Sekiseki stone. It's used for the prison tower Rukia was in during the SS arc, and was used partly to break through the SS barrier by Ichigo and friends. It's basically Soul Reaper kryptonite... yet completely disappears from the series after the arc it first appeared in. This doesn't stop the Vandenreich from marching right in, three times, and curbing the Seireitei because they are quincy. They absorb reishi and all of Society is made of reishi.
  • Code:Breaker:
    • Sakura Sakurakouji with implied Anti-Magic abilities. All Code Breakers' abilities have been shown to be ineffective against her, and she's displayed the ability to cancel out the effects of those powers on others. Canceling out their power's effects may or may not require full body contact, since she seems to hug people every time she does it, causing her friends to name it her "rare power hug attack."
    • The President is also a power-suppressing "Rare Kind" and Sakura's biological father.
    • The President made Inoichi with this ability in mind, although she has to bite someone to take their power rather than just touch them.
  • Nana of Elfen Lied can use her vectors to temporarily disable other Diclonius's vectors.
  • Father of Fullmetal Alchemist can negate the powers of Amestrian alchemists by stomping his foot. He does this by creating a cushion made of souls that reside in Amestris. Xingese alchemy works differently so he can't stop it, or stop the kind used by Scar (which is a hybrid of the Amestrian and Xingese systems developed by Scar's brother).
  • Main character Mikan Sakura from Gakuen Alice has, as one of her Alices (special powers), the ability to nullify any other person's Alice.
  • InuYasha
    • Miroku has one in the form of his arm beads which contain the Vortex in his hand. Since the Vortex is sometimes useful, he simply removes the beads.
    • Houriki in general, which has the ability to purify and/or seal things, especially Youki. The biggest example of this is Mt. Hakurei, which would instantly purify any youkai that gets too close to it except Kanna, who, as she represents nothingness, has no youki of her own. Inu-Yasha was instantly turned into a human once he got too close, while Sesshoumaru was able to temporarily resist the purification due to his sheer power but ultimately had to leave.
  • In Naruto, Neji Hyuuga demonstrated his skill in closing off the chakra pathways of his opponent (and cousin) Hinata. While this does not initially injure her, it prevents her from using her own ninja powers as the fight progresses. She was aiming to do the same thing to him, as they use the same fighting style, but Neji was more experienced and skilled at it and was even able to reverse Hinata's attacks so that she gets chakra points sealed even when he was the one getting hit. In his next fight Neji does the same thing to Naruto, but he's unaware that Naruto is the host of the Nine-Tailed Fox and thus has two chakra networks instead of the usual one.
  • One Piece provides many examples:
    • Salt water paralyzes devil-fruit users but it doesn't necessarily negate their powers. This becomes important when Luffy is stuck underwater; his neck can still stretch.
    • Seastone possess similar properties, rendering a Devil Fruit user weak and unable to so much as stand and robbing them of all their power. So it is used to make handcuffs and jail cells for devil-fruit users. Inside them they are no different than normal humans. They aren't extensively used by the world government due to their rarity, however.
    • Blackbeard has the power of the Dark-Dark Fruit, which uses darkness to nullify all other Devil Fruit abilities. This is especially brutal towards formerly intangible Logia users like Ace, or towards those whose powers would normally soften physical blows like Luffy.
    • There's also Haki, which can nullify the ability of anyone the user makes physical contact with (or if they imbue it in an object, like arrows), which again is significantly powerful against the examples above.
  • In Rurouni Kenshin, the Forest of Darkness negates a warrior's ability to sense chi.
  • Haruhi Suzumiya: Yuki Nagato is able to do this due to the fact that she understands things on a data-level and has the abilities to work on it. It isn't hard for her to nullify any kind of Eye Beam Haruhi makes Mikuru have, by using the right countermeasures. That includes conventional laser beams, hyper-vibration particles and even micro black holes.
  • Slayers:
    • Lina at one point gets a magic-nullifying circlet stuck on her head. Only, as she points out, it's not that it nullifies magic; it's that it causes horrible feedback when she tries to use her powers, so basically all she's doing is shocking herself. Once she decides to ignore the pain, she manages to cast a spell and shock her captors by grabbing them right before she sets off the shock.
    • Later played more seriously when she's the victim of a curse that robs her of all of her magical powers, so she has to go searching for a cure alongside Xellos. In the end, she had to kill the demon Mazenda, since her death was the only solution.
  • A Certain Scientific Railgun:
    • "Capacity Down" is a sound that, when played over loudspeakers, causes intense disorientation to espers as well as making them incapable of using their powers. To normal humans (Level 0's), it's only mildly annoying, and harmless. The Big Bad puts it to use by supplying it to a gang that's comprised solely of Level 0's (and thus would be unaffected by Capacity Down), and then later using it on the good guys in the finale. It backfired on her in the latter case because she was unaware that the good guys had a Level 0 among them, who was able to subsequently destroy the computers playing the audio.
    • A "Capacity Down" device later shows up on A Certain Magical Index. Accelerator counters by throwing a car at the enemy base from a safe distance.
    • Touma Kamijou's right hand, Imagine Breaker, has an Anti-Magic effect, but if it touches someone, they can't use their powers at all until he breaks contact.
  • Mobile Suit Gundam 00 has the Trial System built into the Nadleeh/Seraphim. When it's switched on, every mobile suit connected to Veda shuts down while it's active. It doesn't sound so bad but when you realize that in season 2, Veda was controlled by the Big Bad who used it with every single mobile suit he and his underlings built, it could easily become a Story-Breaker Power. On the other hand, said bad guy's control of Veda meant that he could forcibly disengage the Trial System remotely. So naturally, it's almost never used except in the series finale where it simultaneously puts every single mook out of commission as soon as the Big Bad no longer has access to Veda.
  • In Sekirei, Seo has the ability to nullify a Sekirei's powers if they get within a certain range of him. It was given to him by his best friend Takehito, and he's put it to good use from time to time.
  • The eponymous organization Pandora from Pandora Hearts utilizes Power Nullifiers in the form of seals engraved on the dungeon floors in order to restrain contractors and keep them from summoning their chains. After the Baskervilles take over Pandora, Oz is taken as a prisoner and confined in this way.
  • Andy Hinomiya's esper power in The Unlimited Hyoubu Kyousuke. His ability makes him an outcast among both muggles and espers. It also makes him a fairly effective double agent, since he is immune to psychometry and mind reading.
  • Hunter × Hunter:
    • Characters in the manga are able to learn nen abilities that disable other people's nen. The two shown so far are Kurapika's Chain Jail (which will kill the user if it's used on anyone other than the Phantom Troupe) and Knuckle's Hakoware (a bank loan-themed ability that actually makes the target more powerful with each hit, but accrues interest every ten seconds, shutting off the target's nen for a month if they go over a certain limit and "bankrupt.")
    • Kurapika was able to use a different technique to the same effect, implanting a nen spike inside a person's heart under the condition that it will kill that person if he ever uses nen again.
  • In Shakugan no Shana, when Shana is captured in season 3, she has a small chain wrapped around her wrist that stops her from using her powers.
  • In the The Twelve Kingdoms anime, Enki is subjected to a very nasty version of this. Not only he gets one forcibly put on him, but a similar one is placed on a lady who works for him and Shoryuu — if one of them tries to remove the nullifier, the other will be hit by the magical backlash and die. In the end, the lady decides to sever Enki's cord while clearly knowing it'll kill her, allowing him to escape and rejoin Shoryuu.
  • Princess Oboro from Basilisk is the only one with no fighting skills in her clan, except that her proper ninja skill is being able to negate the powers of any ninja that she looks in the eye to. This power turns out to be the deadliest in the series, so much that even fighters who consider Oboro a weakling are terrified when they're in a position that will involve looking at her in the eye, and it's vital in killing the Big Bad by nullifying his Immortality right when he's reviving himself.
  • In Iris Zero Kuga has the ability to erase other Irises. However, it was revealed that instead of being a magical ability, it was a psychological trick. If you are able to make someone fear what their Iris lets them see they will subconsciously turn their Iris off.

    Card Games 

    Comic Books 
  • In the '90s The Flash series, Savitar was able to take all the power of the Speed Force for himself and his minions, with only Wally being able to resist the drain.
  • Powers, a comic series about human detectives investigating crimes involving the superpowered, has devices called "drainers" that prevent superhumans using their powers while being questioned or detained.
  • Gold Kryptonite could permanently remove the powers of Superman and other Kryptonians, and exposure to a red sun would do it temporarily, as would some varieties of Red Kryptonite. It was brought back after 20+ years but its effects are only temporary. This makes it less scary but more useful as a plot device: depowering Supes forever isn't an option, but you'd be surprised how long fifteen seconds is when you're depowered and a superpowered nutjob is trying to kill you to death.
  • X-Men:
    • The country of Genosha's mutant-power-nullifying collars and a power-nullifying mutant named Wipeout. Remember that thing about a character who wants to be able to turn their own power off not bothering to use the technology available? With brilliant scientists all over the Marvel Universe, why couldn't Rogue get a collar modified into a stylish necklace or bracelet with an on/off switch? This has been addressed in various continuities and adaptions so we're not going to argue about it here. The short of it is sometimes prolonged use causes damage or dangerous Power Incontinence occurs when the device is turned off.
    • The X-Men put something like this on Magik to keep her from escaping when she was made part of the "Extinction Team". (The conditions didn't come with a pardon, and she was only allowed to leave the X-Brig for missions; her suit had a lethal failsafe to prevent her from escaping via teleportation; maybe the problem was simply that it was too dangerous for casual use.)
    • Another mutant, Leech, had this ability as his own mutant power, and on occasion, it's been shown to work on non-mutants. He later showed up in the third X-Men movie, where he was the source of the "mutant cure."
    • Another time, Storm was robbed of her powers temporarily by a device created by mutant inventor Forge.
    • The Mutant Cure was developed by Dr. Kavita Rao and made available to mutants everywhere in Astonishing X-Men. As in the movie, they're so offended by it being called a "cure" that Wolverine violently attacks Beast to prevent him from taking it, out of fear he would become the poster child for mutants Blessed with Suck wanting to do something about their condition.
    • The Marvel Universe contains the Ultimate Nullifier, which... nullifies anyone's power, including heavyweights like Mephisto and Galactus. There's a rookie underground hero calling himself the Ultimate Nullifier, with pistols modeled after the famous weapon that temporarily depower anyone they hit.
    • Moreover, the Initiative made use of SPIN technology to keep its recruits in line — and enforce the SHRA. SPIN removes any and all superhuman abilities permanently. After Komodo was dosed when she refused to go along with the corrupt Initiative of Dark Reign, they managed to develop a "cure" of sorts to restore her powers.
    • In another Marvel comic called DP 7, there is a character whose power is to cure paranormals of their powers. In this story, however, there is a cult of paranormals who believe that their powers are a gift from God, and that to remove those powers is blasphemy.
    • Scrambler, a member of the Marauders super villain team in the X-Men comics, has the ability to disrupt and suppress the powers of other mutants. When he comes into contact with Rogue, their powers interact in such a fashion as to temporarily strip both of them of their superpowers. Same thing happened when the comic version of the aforementioned Leech grabbed Rogue's face. The rest of the Morlocks immediately found out that someone who hangs around guys like Wolverine don't need any powers to kick the ass of anyone who doesn't seem to have any powers beyond "looking like an extra from a Mad Max film".
  • Harold Nelson, a.k.a. "The Rainmaker," from PS238, is able to do this, as well as enhance meta-powers. Suppressor devices, in the form of temporary ray weapons or permanently attached devices also appear.
  • The fourth Empowered collection introduces a villain with this power named "Wet Blanket". Not only can he nullify powers, he also nullifies his fellow villains' enthusiasm with his attitude.
  • The DC Elseworlds story The Golden Age provides the '40s superheroes a Deus Exit Machina from World War II with the power-nullifying Nazi Parsifal. After several heroes were nearly killed by Parsifal, FDR ordered them to all stay out so that a superhero's death didn't hurt morale.
  • Another DC Elseworlds story JLA: Act of God had a giant cosmic storm wash over earth and permanently negated everybody's powers leaving only Badass Normal and tech-based heroes/villains to fight/commit crime (even some of the more fanciful super tech, like Green Lantern's ring, stopped working.)
  • In Ex Machina Mitchell Hundred, formerly known as The Great Machine, gave his two civilian assistants, Kremlin and Bradbury, each a device capable of nullifying his abilities. As a lifelong fan of comic books he was well aware of the danger that he could present if he ever decided to stop working for the public good, and he was also aware that many people are never accepting of the fact that they have changed and are no longer the "good guy." As such, he wanted these two men, who he alone trusted with the secret of his powers and identity, to have the capability of shutting him down if they ever thought that he could no longer be trusted. In the last arc of the series Suzanne, who has become possessed by the power and is working to destroy the world, steals Kremlin's nullifier and goes looking for Mayor Hundred... only for Mitchell to reveal that not only did the nullifier not work, but it had never worked. He knew that Bradbury and Kremlin had been nervous even if they never said so, so he gave them each a piece of junk filled with electronics in order to reassure them of his good intentions.
  • The Savage Dragon villain Negate has the ability to permanently remove the powers of anyone who acquired them through "unnatural means" (i.e. anyone who isn't an alien, supernatural entity, or born with powers). He's eventually used by the Evil Overlord Darklord as the key component in a "nega-bomb" that depowers the entire world.
  • In All Fall Down, Sophie is a walking one, and IQ Squared designed a device to do this to super-powered villains in prison... including his father.
  • In the New 52, Rose Wilson emits a field that turns off invulnerability in her presence, which allows her to fight people like Superboy.
  • In Uncanny Avengers, the S-Man Goat-Faced Girl can shut off the powers of mutants simply by looking at them.

    Fan Works 
  • A common thread in My Little Pony: Friendship Is Magic fan fiction is the need for these sort of devices, typically a ring or other covering placed on a unicorn's horn as a law enforcement restraint on unicorn magic (although one ends up in Wild Sweet And Cool as sports equipment). Effectiveness varies; one fic might have a simple ring work on any pony, even Physical God Luna, while another might have various grades (including one which MELTS when Twilight Sparkle is pissed off sufficiently). Past Sins introduces an anti-magic collar for unicorns.
  • In the Warcraft fic Gift of the Dark Ancestor, the heroine has this, in that anyone she touches cannot access mana, including her magically-powerful true love.

    Films — Live-Action 
  • In Hancock, he and Mary are this to each other.
  • The Kamen Rider Double film Double Forever A-Z/The Gaia Memories of Fate had a new evil Rider named Eternal. Eternal's Maximum Drive Finishing Move initially was capable of permanently disabling any old-generation Gaia Memory, regardless of whether they were a Rider's or a Dopant's.
  • The eponymous high school in Sky High has such a device in its detention room.
  • So did the copycat Zoom: Academy for Superheroes.
  • Superman II allowed Superman to become "permanently" human by absorbing an extremely large dose of red solar radiation. When the Phantom Zone villains arrive on Earth, however, he regains his powers by consuming the energy stored within the Fortress of Solitude. (This is only revealed in the director's cut; the original version has a Deus ex Machina transition between Superman staring at a crystal and reappearing fully powered).
  • X-Men:
    • In The Wolverine, a robotic parasite suppresses Wolverine's healing factor.
    • X-Men: Days of Future Past:
      • When Logan first arrives in the past, Charles doesn't have his psychic powers to verify his story or make their mission easier. This is because he's been taking a serum that lets him walk, at the expense of suppressing his telepathy. Considering the Heroic BSOD he's in the middle of, he doesn't mind. The same serum lets Beast look normal with no apparent ill effects, but it has to be taken periodically by both of them.
      • Nullification collars are used in the Bad Future on mutants in the Sentinel-controlled camps.
  • In the second film of The Mummy Trilogy, Imhotep finds out that he can't use magic in the temple of Ahm Shere. He was hoping to use it to easily kill the Scorpion King, but realizes that Anubis wishes him to fight as a mortal.

  • In Sword of Truth, the Radahan collars take away the magic of anyone wearing them. Oddly enough, at least in the television version, they aren't immune to magic themselves. In the books the collars could be taken off by magic, but only the Sisters of Light could do it, except for Zed, who was so incredibly badass that he not only was able to take one off despite not being a Sister, he took it off of himself while it was suppressing his magic.
  • The "muties" from Sheri S. Tepper's The True Game series suppress the gifts of all nearby Gamesmen.
  • The Dresden Files: A wizard with a thaumaturgic focus and link to another magic-user can also completely lock down another wizard's magic. Very old and skilled wizards can pull it off without any link at all, but they have to be the tip of the mountain in terms of magical skill and power.
  • In The Black Company series, a wizard who knows another wizard's true name can basically Depower them permanently. It also works on The White Rose's inherent Anti-Magic.
  • Septimus Heap: The Darke Vortex is a spell that can temporarily drain people of their Magykal powers. It is used by the Big Bad to trap Marcia Overstrand.
  • In The Dark Hunters series, the magical ability of Were Hunters to shapeshift can be stopped by metriazo collars. If they stay on, however, the Were Hunter will eventually explode from the pent-up magick.
  • Wild Cards:
    • The Trump Card virus, developed by Dr. Tachyon, is meant to cure Xenovirus Takis-A (colloquially known as the setting's eponymous Wild Card). Unfortunately, it is only about 5% effective, and itself lethal in about 30% of attempts. Not surprisingly, most of those who tried it were jokers rather than aces, and even few of those would risk it. And a successful cure can also spell the death of the former wildcarder if his powers kept him alive.
    • Mai Minh, the Vietnamese Ace healer, can permanently reset wildcarders back to nats. While no Aces were known to ask for healing, she would possibly reset powered jokers and joker-aces.
    • Croyd's personal strain of the Wild Card during his Typhoid Croyd period is this trope mixed with mass empowerment, being a forced reroll in the setting's Super Power Lottery. It can turn anyone to any wildcarder - nat, joker, deuce or ace to carrier, Black Queen, joker, deuce or ace. From ace to joker, deuce or Black Queen is this trope in permanent or lethal form.
    • The Astronomer lists the ability to suppress a psychic ace (and thus almost anyone) among his powers. When opposed by Cordelia Chaisson and Demise, he finds out that suppressing only one of them at a time isn't enough...
  • In Kurt Vonnegut's short story "Harrison Bergeron", people with above-average intelligence (i.e. those who can retain a coherent train of thought for more than 10 seconds) must, by federal law, wear headphones that, every 10 seconds, transmit an extremely loud noise to shatter their train of thought. Also, above-average beauty must wear ugly masks, above-average strength must wear weights, etc. The story shows the logical conclusion of "everyone must be equal."
  • The Perry Rhodan universe has a variety of devices that counter or dampen psionic powers either on purpose or as a side effect of their normal operation, from actual traps and prisons that negate such powers inside a given area to relatively common force fields that they cannot penetrate (usually a painful experience for teleporters in particular). Justified in this setting by these powers and much of its advanced technology both invoking fundamentally the same hyperspace physics and energies, which can then naturally end up interfering with each other as the plot demands.
  • The staff at the orphanage in John C. Wright's Chronicles of Chaos have been carefully selected to nullify the abilities of each of the orphans. This allows them to impose a Restraining Bolt on each one.
  • Mistborn:
    • Forcing a Mistborn to burn aluminum causes all of their other metal reserves to be consumed almost instantaneously, leaving them as helpless as a normal human.
    • Likewise, an Allomancer can burn chromium to evoke this effect on another Allomancer through touch. According to Word of God, this metal remains undiscovered as of The Alloy of Law.
  • In Orson Scott Card's little-known Hart's Hope, the hero character is explicitly born as a Power Nullifier, because the Big Bad is a supremely powerful magician (having, amongst other things, enslaved the kingdom's gods).
  • In The Wheel of Time series, it's separating a channeler from the True Source. It's called "gentling" when done to a man, "stilling" when it's done to a woman; the gender-neutral term is "severing". It is possible to reverse the process, but it only works completely if the person restoring the connection is of the opposite sex of the person who was severed, otherwise their channeling strength will return at a greatly reduced capacity. More temporary "shielding" is possible to cut channelers off, and certain places such as stedding and the city of Far Madding are permanently shielded.
  • The Shapeshifter has one of these with a built in Explosive Leash implanted in the back of the COLA's skulls.
  • Grey Murphy of the Xanth series has the power to nullify magic in any target he chooses, or increase a subject's magical talents or properties through a "rebound" effect.
  • The prize-winning series Way Home by Vladimir Zykov features both magical slaves' collars and the combinations of those with this trope, using Anti-Magic, known as "black collars". One of the protagonists survives being put into one, manages to break it and learns to break them on others.
  • Philip K. Dick's classic novel Ubik is about employees of an entire agency of Power Nullifiers. They are a necessary service, since telepaths and other people with potentially dangerous Psychic Powers are commonplace in the setting.
  • In Shadow Ops, anyone who can use magic can Suppress another magic-user's power. This is integral to controlling magic users, and Suppressing someone in the middle of, say, flying, can have nasty consequences. While other branches of the US military actively use their magic offensively in the setting, the US Marine Corps uses "Suppression Lances" that consist of squads of magic-users whose sole job is to Suppress enemy magic-users and kill them with conventional weapons.
  • Alexia of The Parasol Protectorate is a Preternatural, which allows her to revert vampires and werewolves to their mortal states for as long as she is touching them and exorcise ghosts by touching their remains. If not properly disposed of and especially when mummified, the remains of a preternatural can have this same effect over a slowly-increasing area. This phenomenon is responsible for the godbreaker plague.
  • In Vadim Panov's Secret City: Mages abdicating from their Great House and joining Galla's Heresy forfeit their and their children's magic in favor of a single effect, Galla's Sacrificial Tentacle.
  • In Miloslav Knyazev's Full Set series:
    • An archmage uses a power nullifier device of possible pre-war origin to temporarily shut down an opposing sorceress' external power source and is cut down by her muggle husband with a mythril sword.
    • A dragon female uses an anti-dragon amulet of unknown origin during a duel with an unwelcome male dragon suitor. Both male and female are forcibly reduced to their humanoid form, which allows her human and elven allies to kill the male. Later research shows the amulet inscription to say "temporary" without a frame of reference, which may mean centuries for dragons.
  • In V. Ivashchenko's novels across all settings, various sides in various conflicts will use both stationary and mobile means to capture and detain mages. The Black Earl series describe a holding cell in an elven castle and forged restraints (collar, handcuffs, manacles) used by human law enforcers.
  • A variation in Sergey Lukyanenko's Last Watch is an artifact called the Schrödinger's Cat, which takes the form of a furry collar with teeth. Any use of magic causes the Cat to kill the wearer. Only the Other who places the Cat on the neck can take it off. It doesn't prevent magic from being used on the wearer.
  • Forever Gate: The gols use bronze collars to prevent humans from using their innate Shock and Awe powers. They are refered to as "bronze bitches" by said humans.
  • The Quest of the Unaligned: The city of Tonzimmiel is surrounded by a force field which strips the magic from anyone who passes through it. Originally built to make the city a safe haven from the Magocracy that rule the surrounding country of Caederan, 600+ years of the field's effects have caused Tonzimmelians to cease believing in magic altogether.
  • A Mage's Power: There are runes which are known as "prison runes" because they are used to prevent criminal mages from using their powers to escape.
    • Tahart hides them in Annala's maid uniform to make her unable to resist him.
    • When Eric is arrested, a metal collar is snapped on him to prevent him from attacking the officers.

    Live-Action TV 
  • Once Upon a Time:
    • Rumplestiltskin gives Regina a shapeshifting spell so that she can mingle with her subjects and learn what they think of her. The disguise prevents her from using magic and cannot be removed by anyone but Rumplestiltskin.
    • An organization of Witch Hunters "scientifically" nullify magic by injecting people with metals and nanomachines. Although it's later revealed that Peter Pan was stringing them along, and their tools weren't really the Weird Science they thought they were. So it was actually magical Anti-Magic at work.
  • There's a spell in Charmed that can depower a witch for as long as the caster lives, though it was never used by the protagonists due to being very dark magic (the main ingredient is a fresh human heart).
  • In Mutant X, tags (called Subdermal Governors) bolted into the back of the neck were used to nullify mutant powers, though it seems more to torture them when they try to use them than to truly nullify the powers.
  • Buffy the Vampire Slayer: In the episode "Helpless", Buffy, as part of a test by the Watchers' Council on her eighteenth birthday, is hypnotized and Gles is forced to inject a regimen of drugs into her that suppress her Slayer strength.
  • Heroes:
    • The mysterious Haitian has, in addition to memory erasing, the power to suppress other people's powers around him.
    • The Shanti virus and some pills used occasionally by the Company suppress powers. It should be noted that the Shanti virus eventually kills the infected.
    • The characters captured by Nathan Petrelli's goons have a device taped to them that sprays some sort of drug into their nose. It weakens them enough to the point they can't focus enough to use their power.
    • The second eclipse completely nullifies everybody's powers. It's stronger than the Haitian's power, as it reduced Daphne to a crippled state, while she was able to walk around the Haitian. Claire also starts dying of common bacteria, due to not having an immune system from her Healing Factor.
    • Maya and Alejandro Herrera. The latter's power is the ability to cancel out the former's uncontrollable poison emission.
  • In The 4400, Jordan Collier's ability is to depower others by removing the promicin that gives them their powers.
  • In Smallville, blue kryptonite causes Kryptonian powers to disappear, but it needs skin contact to work. Red sunlight, magic, and various alien devices can also take away Clark's powers. This case is notable for having a guy who DID use it to lead a normal life. It later bit him in the ass.
  • Stargate SG-1 has the Anti-Prior device the team cooked up against the Ori. It emits an inaudible sound that makes Priors unable to use their psychic powers; however, both Damaris and Daniel Jackson/Merlin were able to overcome it given sufficient time.
  • The Rada'Han is a collar in Legend of the Seeker used to nullify a person's magical ability. In one case, it was used to prevent a cursed person from turning into a monster. The Pristinely Ungifted are rare individuals completely unaffected by magic. When one is first introduced, she is able to walk through what is, essentially, a magical minefield as if it wasn't there.
  • In Painkiller Jane, neuros can be rendered harmless by "chipping" them with a special gun that implants a control chip into the back of their heads, counteracting their abilities. It doesn't work on advanced neuros, though.
  • In Star Trek: Deep Space Nine, the Obsidian Order had a prototype device that would prevent a Founder from returning to their natural gelatinous state, with potentially lethal results for the changeling if the device is left on for extended periods.
  • In the final season of Misfits, Alex receives the power to permanently destroy other people's powers by having sex with them.
  • One of Zin's fugitives used a ray gun style device on Cole in Tracker, nullifying his Cirronian abilities until Mel discovered she could power him back up.

    Tabletop Games 
  • Tabletop Game/Herosystem:
    • A power is devoted explicitly to this, called Drain, which reduces the affected power temporarily (or possibly permanently).
    • There is also Suppress, which is similar to Drain except Drain "damages" a power or characteristic and it automatically heals over time, while Suppress reduces the power only as long as the Suppress is maintained.
  • Dungeonsand Dragons:
    • The spell "Mordenkhainen's Disjunction" can strip magic permanently from magic items. Also fits this trope in that, if a spellcaster successfully strips the power from an Artifact-level magic item (which has very low odds to even work unless the character has an obscenely high caster level), the caster himself must make a saving throw or permanently lose all magic-related abilities and spellcasting. Fail the saving throw, and absolutely nothing (not even somebody else casting the ultra-broken "Miracle" or "Wish" spells) can restore the caster's magic. And just in case you didn't think the rules were already stacked to tell you casting Disjunction on an Artifact is a Very Bad Idea, there's also a 95% chance that some god, demon or other ludicrously powerful being connected to the Artifact will show up to punish the caster.
    • There exist an expensive item, anti-magic shackles, for restraining magic-users.
    • Some Edition 3.5 spells can supress or remove supernatural abilities. "Trait Removal" or "Expunge the Supernatural" are temporary, while "Spurn the Supernatural" is permanent and can't be dispelled (but is high-level and costly).
  • Power Nullifiers are known as "pulsing" effects in SenZar, and they're even more feared than in most other games, because of SenZar's munchkin-friendly design.
  • * Lejendary Adventures. Morben's Supernatural Shackles would completely prevent the victim from using any kind of magic, including magical items.
  • The Dark Eye has the substance of banedust as well as some divine rituals to permanently drain the magic ability of a person, used frequently to punish criminal wizards. Enchainments of iron serve well as a temporary version.

    Video Games 
  • In City of Heroes, the Bio-Energy Feedback Inducer is a power-draining weapon used by the "Sappers." It works by draining your endurance, which all powers need to operate. EMP and electrical powers can do this as well, but not drain you completely in a single hit like a Sapper can.
  • Disgaea:
  • Fire Emblem:
    • A recurring boss in Fire Emblem: Blazing Sword is a Magic Seal named Kishuna. As his class name implies, he negates all magic in a 15-space radius of himself. It's all he can do, but since his speed is insane it can take some time to kill him.
    • The skill "Nihil" / "Mikiri" in the Jugdral and Tellius sagas. In the Jugdral games, it nullifies all enemy Critical Hit-based, and Special Sword skills ; in the Tellius games, it negates all enemy Battle skills. The Tellius games have in addition the Skill "Parity", which has the same effect but extended to the Skill's owner as well, and also negates both the skill's owner and his foe's support and terrain bonuses.
  • Guilty Gear has Sol's headband. It's technically a Power Limiter, but it makes him so weak his fire magic is completely nullified. Unless he compensates with an artifact that boosts specifically fire magic.
  • In Guild Wars Mesmers can drain an enemies energy, interrupt spells that are being cast and even entirely disable spells from being used for a time.
  • World of Warcraft
    • All classes have some form of a silence or interrupt effect. The first prevents the target from casting any spells until it expires, the other interrupts a spell that's being cast and prevents them from casting any spell of the same "school" e.g. interrupt a fireball and it stops them casting any fire spell. Due the devastating nature of being locked out like this for many classes (shadow priests until recently had zero non-shadow offensive spells) the duration of the silence or lockout is measured in a scant few seconds.
    • Anub'Rekhan is a boss notable for having an area of effect and particularly extreme Power Nullifier. When he casts it anyone near is unable to cast any spell, use any ability, or even just use a normal attack.
  • Tokimeki Memorial:
    • In Tokimeki Memorial 2, when Sou-Banchou, the leader of Hibikino Town's Delinquents, turns into his Giant Form, he gains the "Chou-Gankiri" (Super Insight) ability, which nullifies your Sports Club Hi-Ougi should you have one.
    • In Tokimeki Memorial 4, the Skill "Heart Unlocking Technique" / "Kokoro no Kaijoujutsu" negates the girls' negative Skills, such as Satsuki's "Noble" / "Kouki", and Tsugumi's "Tsun" Skills.
  • BlazBlue:
    • Hakumen's Nox, Ookami, has this ability, rendered in-game as being able to null out projectiles, and in-story as otherwise immortal characters (Namely Nu-13 and Terumi) don't want it near them.
      Terumi: Hey, Hakumen, I really don't want you touching me with your Ookami, so how about we do this...
    • One Celica A. Mercury has the uncontrollable ability to neutralize all seithr in an area around her. As seithr is required to use all ars magus and ars armagus, as well as the Azure Grimoire, she functions as this around most entities. Ragna's right arm and eye go completely numb around her as a result; likewise, the aforementioned Terumi shits himself if he catches sight of her (at the end of his CP Arcade, he screams for Phantom to get him out of there).
    • Azrael, one of the three newcomers from Chrono Phantasma, is an interesting case in which he has a Power Nullifier on himself that he purposefully applied. The Nullifier in question, his Enchant Dragunov tattoos, is activated/deactivated at will, and comes in three levels, with the third level unleashing his true power. The reason for his willing restriction was to draw out the battles he engaged in since fighting at full strength meant opponents who died easily, thus ending fights too quickly.
  • In Prototype, Alex gets injected with a parasite by Specialist Cross that disables his flashiest powers, though he still has Super Strength, Super Speed and the ability to disguise himself. He then spends the next few missions working with another scientist on trying to get rid of said parasite, with the final result being that he managed to gain new powers when he comes back.
  • Pokémon contains several moves that can do this.
    • Disable locks out the target's most recently-used move for a few rounds.
    • Imprison locks out any moves the target shares with the user until one of them switches out.
    • Gastro Acid completely locks out the target's ability (such as the Shadow Tag ability that makes Wobbuffet a Game Breaker) until the victim switches.
    • Finally, Grudge is a Taking You with Me version of this trope — if the user dies the round it's used, the target loses all the use points for the attack that last connected.
  • In Dragon Age, the Qunari treat their mages (called Saarebas — "dangerous thing") even worse than humans (and that's saying something), using magic-nullifying collars to keep them in line. The collars are controlled remotely. Just in case, though, they still cover the mages' eyes and sew their mouths shut.
  • Dishonored has the Overseers, who wield special music boxes that prevents Corvo from using his powers. However, that does not stop him blowing their brains out.
  • in Xenoblade Egil has a device called the Apocrypha made in order to disable Shulk's Monado, shorting out its ability to damage his Face Mechon along with its other powers.
  • The Elder Scrolls III: Morrowind features a remarkably simple way to keep slaves from casting spells: locked bracers enchanted with a small but constant magicka-drain effect. It takes a while to fully work, but once the magicka hits zero it's not coming back up barring magicka potions or removal of the bracers followed by sleep. No magicka, no spells.
  • In Mario & Luigi: Dream Team, Antasma has the unique ability to separate Dreamy Luigi from Mario and imprison him within one of his Antasmunchies. This lowers Mario's stats and leaves him with only his basic jump attack, so freeing Luigi ASAP is in one's best interest, though locating him isn't always an easy task...

    Web Comics 
  • Gamma from Gunnerkrigg Court prevents Zimmy's powers from acting up (or at least lessens their magnitude) simply by her presence. But it doesn't work as well when she's asleep — and she's pretty much Zimmy's only means of controlling her powers. Antimony can play this role for Zimmy in a pinch, but she's nowhere near as strong as Gamma.
  • At least one Spellwolf from Dominic Deegan has shown the ability to cast the spell "Null Magic".
  • The Dreamland Chronicles: Humans in Dream Land have powers, always including flight, unless they are afraid. The pirates exploit this.
  • The Dragon Doctors has Kili's tattoos, when applied to any other shaman than herself.
  • The purpose of Agatha's locket in Girl Genius is to suppress her spark. Later in the story, it plays a similar, but different purpose.
  • Max Catnap of the Crossover Wars is a walking literal example of this trope. He has the power to nullify other magical or powerful characters by simply touching them.
  • In Spacetrawler, the Ites are uniquely qualified for police work because they emit an anti-telekinesis field.
  • In Kubera, the Sword of Re is a god-level item designed to fight sura. It inhibits the regeneration of anything it strikes (specifically, it brings it down to normal human regeneration, which is basically nonexistent), from sura to gods, making them far easier to kill. While most sura and any god could easily wield the weapon, the problem is that it does the same thing to the owner as well, and the only way to give up the sword is to die. This makes it a perfect weapon for a human, but every sura who has tried to use it has inevitably died quickly and messily.

    Web Original 
  • In the Whateley Universe, there may not be gizmos that work as power nullifiers (yet), but some mutants (such as Negator and Damper) have that ability. It does backfire somewhat against Tennyo, however, as she actually gets more powerful with her mutant abilities suppressed; she just starts using the power of the Class X Entity contained inside her.
  • In the Global Guardians PBEM Universe:
    • Purge has the power to turn off metahuman powers, but not magic or powers gained through technology.
    • Scramble can cause metahuman powers to misfire and not work properly (though they do tend to still work somehow).
  • SCP Foundation's SCP-514. Whenever in contact with the pigeons' nullifying "aura", every weapon (bombs, guns, tanks, baseball bats, knives, etc.) is rendered completely useless and are even destroyed after prolonged exposure. Even objects not designed to be weaponized like pens were rendered useless if used for violent intent. In addition, the pigeons' ability can completely suppress the negative emotions and intent of all sentient beings, no matter how violent, which makes the capture of SCP-514 nearly impossible.
  • In Trinton Chronicles, Elijah's power allows him to nullify a power by storing it in a crystal temporarily.
  • In Worm, Hatchet Face shuts down the powers of anyone near him.
  • Phaeton has zero elements which can be used to negate magic, scramble psychic waves and toggle genes.
  • The Lay of Paul Twister: Paul Twister]] has "the Twist," the ability to screw up active magic by touch. It's apparently not under his conscious control, and he remarks several times (though it's yet to be shown) that the Twist is not perfect and doesn't make him invincible against magic.

    Western Animation 
  • Avatar: The Last Airbender:
    • Disruptions in Elemental Powers of the series' Benders occur during temporary meteorological events. Firebenders and Waterbenders draw their power from the sun and moon, respectively. When solar or lunar eclipse occurs, the affiliated Benders lose their powers for its duration. It's also possible to stop Waterbending for good by destroying the moon through its totemic spirit, (which, while easier than it sounds in this setting, is not a good idea, as it will enrage the moon's partner, the Ocean).
    • In the series finale "Sozin's Comet". Aang permanently does this to Ozai, using energy-bending he learned from a giant Lion Turtle.
    • Badass Normal martial artist Ty Lee has learned to disable the Elemental Powers of Benders by striking Pressure Points to block the flow of chi (resulting in considerable pain for some of her victims). In Sequel Series The Legend of Korra, Ty Lee's chi-blocking technique is employed by Anti-Bending Faction, the Equalists. The Leader of the Equalists, Amon, claims to be able to permanently remove bending, with the implication he uses the same technique Aang used. In actuality, he's using a form of Bloodbending.
  • There are two in Danny Phantom:
    • The Specter Deflector wards off anything ectoplasmic, so if Danny were to turn into his ghostly Super Hero counterpart, he'd get a nasty electric zap.
    • The other is the more straightforward version of this trope: the Plasmius Maximus, designed to nullify ghost powers for a good three hours.
  • In the animated version of Legion of Super Heroes this was Nemesis Kid's power.
  • In X-Men: Evolution, Leech's power extends to more than shutting down powers: it can shut down anything. When he used it to its fullest, a good chunk of the city lost power. Like movie Leech, he can also undo physical mutations, such as Spyke's permanent bone-armor vanishing, restoring his season one appearance until the effect ended.
  • The Powerpuff Girls features Antidote X, first appearing in "Slumbering With the Enemy". Mojo Jojo threw it at the title superheroes in said episode to reduce them to normal little girls, though this obviously didn't affect subsequent episodes. The Movie reveals that it was initially created to get Mojo out of his One-Winged Angel form, though the girls briefly considered using it on themselves so they would be better accepted without superpowers.
  • On Buzz Lightyear of Star Command, Zurg manages to turn off Mira's powers by setting her in a box that disrupts her concentration whenever she tries to use her powers. Since concentration is required, well....
  • Generator Rex:
    • The title character has permanent Power Nullification as one of his primary powers, though considering how powers are handed out in the Generator Rex universe, its not really that threatening except against the few EVOs with a Magneto-like ideology.
    • Feakins from the episode "Deadzone" exhibits some sort of Nanite deadzone around himself. If Rex is in too close a vicinity to him, his powers don't work.
  • An indeterminate variant is used by Lex Luthor on Lord Superman at the end of the Justice League two-part episode "A Better World". What exactly happened to his powers are unknown but he's at least able to be captured and detained by conventional shackles once it's been used on him.
  • My Little Pony: Friendship Is Magic: The "Equestria Games" use disabling spells (which look like airport metal detectors) that unicorns must pass through to prevent cheating in the events.