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-> '''Gerrard:''' But it doesn't ''do'' anything!\\
'''Hanna:''' No--it ''does'' nothing.
-->-- ''TabletopGame/MagicTheGathering'', [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=4437 Null Rod]] FlavorText

A super-power or AppliedPhlebotinum device that "turns off" either all super-powers or those from a certain MetaOrigin. Can also be referred to as a "power neutralizer".

This can be temporary or permanent; the temporary version is generally used as either part of a BroughtDownToNormal plot or as a plot device to enable villains who normally wouldn't stand a chance against the heroes, while the permanent {{Depower}}ing version is usually a way to threaten someone without trying to kill them. {{Tailor Made Prison}}s for super villains usually incorporate one into the design.

Curiously, very few people who say IJustWantToBeNormal create a modified version of these for their own personal use, even if the technology seems to be relatively available. Even worse, if a hero is BlessedWithSuck, [[ReedRichardsIsUseless not even the smartest scientists allied with the side of Good]] seem able to invent a safe one.

Related to PowersAsPrograms. For countering the ''products'' of those powers, see AntiMagic. If the power has already been used, DispelMagic can remove the effects. PowerLimiter is a weaker version. NoSell is when a character ignores, not nullifies, another's powers. {{Mage Killer}}s often weaponize this ability, as they do with AntiMagic. See also the KryptoniteProofSuit, which can be used to resist {{Weaksauce Weakness}}es.

Please do not confuse this trope with AntiMagic. A laconic way of thinking about them is that this trope is a tool and AntiMagic is an ability.



[[folder:Anime & Manga]]
* In ''Manga/{{Bleach}}'': There's a type of stone in the Soul Society called Sekiseki stone. It's used for the prison tower Rukia was in during the SS arc and also the wall around fortress of the 13 Court Guard Squads. This is why its so difficult for prisoners to escape and also for intruders to break in.
* ''Manga/CodeBreaker'':
** Sakura Sakurakouji with implied AntiMagic abilities. All Code Breakers' abilities have been shown to be ineffective against her, and she's displayed the ability to cancel out the effects of those powers on others. Canceling out their power's effects may or may not require full body contact, since she seems to hug people every time she does it, causing her friends to name it her "rare power hug attack."
** The President is also a power-suppressing "Rare Kind" [[spoiler: and Sakura's biological father]].
** The President made Inoichi with this ability in mind, although she has to bite someone to take their power rather than just touch them.
* Nana of ''Manga/ElfenLied'' can use her vectors to temporarily disable other Diclonius's vectors.
* [[BigBad Father]] of ''Manga/FullmetalAlchemist'' can negate the powers of Amestrian alchemists by stomping his foot. He does this by [[spoiler: creating a cushion made of souls that reside in Amestris]]. Xingese alchemy works differently so he can't stop it, or stop the kind used by Scar (which is [[spoiler:a hybrid of the Amestrian and Xingese systems developed by Scar's brother]]).
* Main character Mikan Sakura from ''Manga/AliceAcademy'' has, as one of her Alices (special powers), the ability to nullify any other person's Alice.
* ''Manga/InuYasha'':
** Miroku has one in the form of his arm beads which contain the Vortex in his hand. Since the Vortex is sometimes useful, he simply removes the beads.
** Houriki in general, which has the ability to purify and/or seal things, especially Youki. The biggest example of this is Mt. Hakurei, which would instantly purify any youkai that gets too close to it except Kanna, who, as she represents nothingness, has no youki of her own. Inu-Yasha was instantly turned into a human once he got too close, while Sesshoumaru was able to ''temporarily'' resist the purification due to his sheer power but ultimately had to leave.
* In ''Manga/{{Naruto}}'', Neji Hyuuga demonstrated his skill in closing off the chakra pathways of his opponent (and cousin) Hinata. While this does not initially injure her, it prevents her from using her own ninja powers as the fight progresses. She was aiming to do the same thing to him, as they use the same fighting style, but Neji was more experienced and skilled at it and was even able to reverse Hinata's attacks so that ''she'' gets chakra points sealed even when ''he'' was the one getting hit. In his next fight Neji does the same thing to Naruto, but [[spoiler:he's unaware that Naruto is the host of the Nine-Tailed Fox and thus has two chakra networks instead of the usual one]].
* ''Manga/OnePiece'' provides many examples:
** Salt water paralyzes devil-fruit users but it doesn't ''necessarily'' negate their powers. This becomes important when Luffy is stuck underwater; his neck can still [[RubberMan stretch]] if it is pulled by someone else.
** Seastone is related to salt water (hence the name) and so it possess similar properties, rendering a Devil Fruit user weak and unable to so much as stand and robbing them of all their power. So it is used to make handcuffs and jail cells for devil-fruit users. Inside them they are no different than normal humans. They aren't extensively used for other purposes by the world government due to their rarity.
** Blackbeard has the power of darkness, which works similar to a [[PoweroftheVoid black hole]] - it generates darkness, that pulls in everything, including devil fruit powers, which allows him to cancel the abilities of other Fruit users while he remains in contact with them.
* In ''Manga/RurouniKenshin'', the Forest of Darkness negates a warrior's ability to sense chi.
* ''LightNovel/HaruhiSuzumiya'': Yuki Nagato is able to do this due to the fact that she understands things on a data-level and has the abilities to [[PowersAsPrograms work on it]]. It isn't hard for her to nullify any kind of EyeBeam [[spoiler:Haruhi makes Mikuru have]], by using the right countermeasures. That includes conventional laser beams, hyper-vibration particles and even ''micro black holes''.
* ''LightNovel/{{Slayers}}'':
** Lina at one point gets a magic-nullifying circlet stuck on her head. Only, as she points out, it's not that it nullifies magic; it's that it causes horrible feedback when she tries to use her powers, so basically all she's doing is shocking herself. Once she decides to ignore the pain, she manages to cast a spell ''and'' shock her captors by grabbing them right before she sets off the shock.
** Later is the victim of a curse that robs her of ''all'' of her magical powers, so she has to go searching for a cure alongside Xellos. [[spoiler:In the end, she had to kill the demon Mazenda, since [[NoOntologicalInertia her death was the only solution]].]]
* ''Manga/ACertainScientificRailgun'':
** "Capacity Down" is a sound that, when played over loudspeakers, causes intense disorientation to espers as well as making them incapable of using their powers. To normal humans (Level 0's), it's only mildly annoying, and harmless. [[spoiler:The BigBad puts it to use by supplying it to a gang that's comprised solely of Level 0's (and thus would be unaffected by Capacity Down), and then later using it on the good guys in the finale. It backfired on her in the latter case because she was unaware that the good guys had a Level 0 among them, who was able to subsequently destroy the computers playing the audio.]]
** A "Capacity Down" device later shows up on ''Manga/ACertainMagicalIndex''. Accelerator counters by throwing a car at the enemy base from a safe distance.
* ''Anime/MobileSuitGundam00'' has the Trial System built into the Nadleeh/Seraphim. When it's switched on, every mobile suit connected to Veda shuts down while it's active. It doesn't sound so bad but when you realize that in season 2, Veda was controlled by the BigBad who used it with every single mobile suit he and his underlings built, it could easily become a StoryBreakerPower. On the other hand, said bad guy's control of Veda meant that he could forcibly disengage the Trial System remotely. So naturally, it's almost never used except in the series finale where it simultaneously puts every single {{mook}} out of commission as soon as the BigBad no longer has access to Veda.
* In ''Manga/{{Sekirei}}'', Seo has the ability to nullify a Sekirei's powers if they get within a certain range of him. It was given to him by his best friend Takehito, and he's put it to good use from time to time.
* The eponymous organization Pandora from ''Manga/PandoraHearts'' utilizes Power Nullifiers in the form of seals engraved on the dungeon floors in order to restrain contractors and keep them from summoning their [[{{Familiar}} chains]]. [[spoiler:After the Baskervilles take over Pandora, Oz is taken as a prisoner and confined in this way.]]
* Andy Hinomiya's esper power in ''Anime/TheUnlimitedHyoubuKyousuke''. His ability makes him an outcast among both muggles and espers. It also makes him [[spoiler:a fairly effective double agent, since he is immune to {{psychometry}} and mind reading.]]
* ''Manga/HunterXHunter'':
** Characters in the manga are able to learn [[FunctionalMagic nen abilities]] that disable other people's nen. The two shown so far are Kurapika's Chain Jail (which will kill the user if it's used on anyone other than the [[CarnivalOfKillers Phantom Troupe]]) and Knuckle's Hakoware (a [[LoanShark bank loan-themed]] ability that actually ''makes the target more powerful'' with each hit, but accrues interest every ten seconds, shutting off the target's nen for a month if they go over a certain limit and "bankrupt.")
** Kurapika was able to use a different technique to the same effect, implanting a nen spike inside a person's heart under the condition that it will kill that person if he ever uses nen again.
* In ''LightNovel/ShakuganNoShana'', when Shana is captured in season 3, she has a small chain wrapped around her wrist that stops her from using her powers.
* In the ''LightNovel/TheTwelveKingdoms'' anime, [[spoiler:Enki]] is subjected to a very nasty version of this. [[spoiler:Not only does he get one forcibly put on him, but a similar one is placed on a lady who works for him and Shoryuu -- if one of them tries to remove the nullifier, ''the other will be hit by the magical backlash and die''. In the end, the lady decides to sever Enki's cord [[HeroicSacrifice while clearly knowing it'll kill her]], allowing him to escape and rejoin Shoryuu.]]
* Princess Oboro from ''Manga/{{Basilisk}}'' has her proper ninja skill being able to negate the powers of any ninja that she looks in the eye. This power turns out to be the ''deadliest'' in the series, so much that even fighters who consider Oboro a weakling are ''terrified'' when they're in a position that will involve looking at her in the eye, [[spoiler:and it's vital in killing '''the BigBad''' by nullifying his {{Immortality}} ''right when he's reviving himself''.]]
* In ''Manga/IrisZero'' [[spoiler:Kuga]] has the ability to erase other [[MagicalEye Irises]]. [[spoiler:However, it was revealed that instead of being a magical ability, it was a psychological trick. If you are able to make someone fear what their Iris lets them see they will subconsciously turn their Iris off]].
* In the anime adaptation of ''VideoGame/ArcanaFamiglia'', Luca's Arcana power, Il Bacio dell'Angelo, nullifies another Arcana Card user's powers.
* ''Manga/MyHeroAcademia'': 80% of the population has a "Quirk" and many are in traning to become superheroes. The hero "Eraserhead" has the Quirk to erase other people's Quirks, but only when he is looking at them. The effect wears off when he blinks or looks away, and it doesn't work on people whose Quirks have changed their body structure, i.e. a guy with a tail won't suddenly lose his tail around Eraserhead.
** Later in the Internship Arc, the main villians, Shie Hassakai, are developing a chemical that can nullify peoples' Quirks.
* In ''Manga/BungouStrayDogs'', nobody can use their ability while any part of Dazai's body is in contact with any part of their body (or, if their ability creates an extension like Akutagawa's coat or Steinbeck's vines, in contact with that).

[[folder:Card Games]]
* ''TabletopGame/MagicTheGathering'' has a number of different Power Nullifiers depending on what exactly you want to nullify.
** [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=4437 Null Rod]], quoted above, gets all artifacts;
** [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=48432 Arrest]] gets one particular creature;
** [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=129526 Pithing Needle]] turns off one particular card;
** [[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=5711 Back to Basics]] turns off nonbasic lands...
* ''TabletopGame/YuGiOh'': Kumongous, at the cost of two Kaiju counters from anywhere on the field, can negate the effects of a monster that is summoned. Furthermore, that monster cannot attack that turn.

[[folder:Comic Books]]
* In the '90s ''ComicBook/TheFlash'' series, Savitar was able to take all the power of the Speed Force for himself and his minions, with only Wally being able to resist the drain.
* ''ComicBook/{{Powers}}'', a comic series about human detectives investigating crimes involving the superpowered, has devices called "drainers" that prevent superhumans from using their powers while being questioned or detained.
* Gold Kryptonite could permanently remove the powers of Comicbook/{{Superman}} and [[ComicBook/{{Supergirl}} other Kryptonians]], and exposure to a red sun would do it temporarily, as would some varieties of Red Kryptonite. It was brought back after 20+ years but its effects are only temporary. This makes it less scary but more useful as a plot device: depowering Supes forever isn't an option, but you'd be surprised how long fifteen seconds is when you're depowered and a superpowered nutjob is trying to [[MemeticMutation kill you to death]].
* ''ComicBook/XMen'':
** The country of Genosha's mutant-power-nullifying collars and a power-nullifying mutant named Wipeout. Certain mutants who dislike their powers have tried to use this rid themselves of their powers. The possibility has been addressed in various continuities and adaptions so we're not going to argue about it here. The short of it is sometimes prolonged use causes damage or dangerous PowerIncontinence occurs when the device is turned off.
** The X-Men put something like this on Magik to keep her from escaping [[BoxedCrook when she was made part of the "Extinction Team"]]. (The conditions didn't come with a pardon, and she was only allowed to leave the X-Brig for missions; her suit had a lethal failsafe to prevent her from escaping via teleportation; maybe the problem was simply that it was too dangerous for casual use.)
** Leech, had this ability as his own mutant power, and on occasion, it's been shown to work on non-mutants. He later showed up in the third ''X-Men'' movie, where [[spoiler:he was the source of the "mutant cure."]]
** Storm was robbed of her powers temporarily by a device created by mutant inventor Forge.
** The Mutant Cure was developed by Dr. Kavita Rao and made available to mutants everywhere in ''[[ComicBook/XMen Astonishing X-Men]]''. As in the movie, they're so offended by it being called a "cure" that ComicBook/{{Wolverine}} violently attacks Beast to prevent him from taking it, out of fear he would become the poster child for mutants BlessedWithSuck wanting to do something about their condition.
** The Marvel Universe contains the Ultimate Nullifier, which... nullifies ''anyone's'' power, including heavyweights like Mephisto and Galactus. There's a rookie underground hero calling himself the Ultimate Nullifier, with pistols modeled after the famous weapon that temporarily depower anyone they hit. The Ultimate Nullifer -- the weapon, not the hero -- doesn't just nullify a being's power. It erases them from existence. The catch is that the weapon will backfire on its wielder if they do not fully comprehend the nature of their target.
** The Initiative made use of SPIN technology to keep its recruits in line -- and enforce the SHRA. SPIN removes any and all superhuman abilities ''permanently''. After Komodo was dosed when she refused to go along with the corrupt Initiative of ''Comicbook/DarkReign'', they managed to develop a "cure" of sorts to restore her powers.
** In another Marvel comic called ''ComicBook/DP7'', there is a character whose power is to cure paranormals of their powers. In this story, however, there is a cult of paranormals who believe that their powers are a gift from God, and that to remove those powers is blasphemy.
** Scrambler, a member of the Marauders super villain team in the ''ComicBook/XMen'' comics, has the ability to disrupt and suppress the powers of other mutants. When he comes into contact with Rogue, their powers interact in such a fashion as to temporarily strip both of them of their superpowers. Same thing happened when the comic version of the aforementioned Leech grabbed Rogue's face. The rest of the Morlocks immediately found out that someone who hangs around guys like Wolverine don't need any powers to kick the ass of anyone who doesn't seem to have any powers beyond "looking like an extra from a ''Film/MadMax'' film".
* Harold Nelson, a.k.a. "The Rainmaker," from ''ComicBook/PS238'', is able to do this, as well as enhance meta-powers. Suppressor devices, in the form of temporary ray weapons or permanently attached devices also appear.
* The fourth ''ComicBook/{{Empowered}}'' collection introduces a villain with this power named "Wet Blanket". Not only can he nullify powers, he also nullifies his fellow villains' enthusiasm with his attitude.
* The DC Elseworlds story ''ComicBook/TheGoldenAge'' provides the '40s superheroes a DeusExitMachina from World War II with the power-nullifying Nazi Parsifal. After several heroes were nearly killed by Parsifal, FDR ordered them to all stay out so that a superhero's death didn't hurt morale.
* Another DC Elseworlds story ''ComicBook/JLAActOfGod'' had a giant cosmic storm wash over Earth and permanently negate everybody's powers leaving only BadassNormal and tech-based heroes/villains to fight/commit crime (even some of the more fanciful super tech, like GreenLantern's ring, stopped working.)
* In ''ComicBook/ExMachina'' Mitchell Hundred, formerly known as The Great Machine, gave his two civilian assistants, Kremlin and Bradbury, each a device capable of nullifying his abilities. [[GenreSavvy As a lifelong fan of comic books]] he was well aware of the danger that he could present if he ever decided to stop working for the public good, and he was also aware that many people are never accepting of the fact that they have changed and are no longer the "good guy." As such, he wanted these two men, who he alone trusted with the secret of his powers and identity, to have the capability of shutting him down if they ever thought that he could no longer be trusted. In the last arc of the series, Suzanne, who ''has'' become possessed by the power and is working to destroy the world, steals Kremlin's nullifier and goes looking for Mayor Hundred...[[spoiler: only for Mitchell to reveal that not only did the nullifier not work, but it had ''never'' worked. He knew that Bradbury and Kremlin had been nervous even if they never said so, so he gave them each a piece of junk filled with electronics in order to reassure them of his good intentions.]]
* ''ComicBook/TheSavageDragon'' villain Negate has the ability to permanently remove the powers of anyone who acquired them through "unnatural means" (i.e. anyone who isn't an alien, supernatural entity, or born with powers). He's eventually used by the EvilOverlord Darklord as the key component in a "nega-bomb" that depowers the entire world.
* In ''ComicBook/AllFallDown'', Sophie is a walking one, and IQ Squared designed a device to do this to super-powered villains in prison... including his father.
* In the ComicBook/{{New 52}}, Rose Wilson emits a field that turns off invulnerability in her presence, which allows her to fight people like ComicBook/{{Superboy}}.
* In ''ComicBook/UncannyAvengers'', the S-Man Goat-Faced Girl can shut off the powers of mutants simply by looking at them.
* In ''ComicBook/{{Convergence}}'', the domes act as this, cutting people off from their power sources for approximately a year (though ComicBook/{{New 52}} ComicBook/{{Earth 2}} is exempt).

[[folder:Fan Works]]
* A common thread in ''WesternAnimation/MyLittlePonyFriendshipIsMagic'' fan fiction is the need for these sort of devices, typically a ring or other covering placed on a unicorn's horn as a law enforcement restraint on unicorn magic (although one ends up in ''Fanfic/WildSweetAndCool'' as sports equipment). Effectiveness varies; one fic might have a simple ring work on any pony, even PhysicalGod Luna, while another might have various grades (including one which MELTS when Twilight Sparkle is pissed off sufficiently).
** ''Fanfic/PastSins'' introduces an anti-magic collar for unicorns.
** In ''FanFic/{{Asylum}}'', restraining rings are used on unicorn patients as a safety precaution for both the staff and themselves. Unfortunately for Twilight, this makes her life a lot harder.
* In the ''VideoGame/{{Warcraft}}'' fic ''[[http://www.fanfiction.net/s/6486094/1/Gift_of_the_Dark_Ancestor Gift of the Dark Ancestor]]'', the heroine has this, in that anyone she touches cannot access mana, including her magically-powerful true love.
* In the ''Franchise/StarWars'' fanfic "[[https://www.fanfiction.net/s/1759755/1/Can-What-is-Lost-be-Found Can What Is Lost Be Found]]", Obi Wan Kenobi is captured, and when he's rescued, he has a device attached behind his ear to prevent him using his Force abilities. The healers are cautious about when to remove it, as they fear Obi Wan may lash out and hurt himself or someone else if he doesn't know what's going on before it's attmepted.
* Another ''Franchise/StarWars'' fic, "[[https://www.fanfiction.net/s/4928281/1/Misplaced-Jedi Misplaced Jedi]]", has an older Obi Wan captured and when Anakin rescues him, he's got a collar around his neck to keep him from accessing the Force.
* In ''Fanfic/ChrysalisVisitsTheHague'', Chrysalis' tremendous magic power is curbed (pretty rudimentarily) by the humans by wrapping her horn in wires and tin foil and feeding it a constant stream of electricity from a battery.
* ''Fanfic/WithStringsAttached'':
** It has the "Neut Cuffs" that the cop in New Zork puts on Paul to nullify his Ability. Too bad for him that [[spoiler:Paul was specifically built by Jeft so his powers couldn't be nullified, since if they were, he would explode from the energy he contained.]]
** The ambushers at the hermit's cave in ''Fanfic/TheKeysStandAlone: The Soft World'' employ a drain wrap against Paul with similar non-results.

[[folder:Films -- Live-Action]]
* In ''Film/{{Hancock}}'', [[spoiler:he and Mary]] are this to [[spoiler: each other. Too much physical proximity and they are normal humans]].
* The ''Series/KamenRiderDouble'' film ''Double Forever A-Z/The Gaia Memories of Fate'' had [[spoiler:a new evil Rider named Eternal. Eternal's Maximum Drive FinishingMove initially was capable of permanently disabling any old-generation Gaia Memory, regardless of whether they were a Rider's or a Dopant's.]]
%%* The eponymous high school in ''Film/SkyHigh2005'' has such a device in its detention room.
%%* copycat ''Film/ZoomAcademyForSuperheroes''.
* ''Film/SupermanII'' allowed Franchise/{{Superman}} to become "permanently" human by absorbing an extremely large dose of red solar radiation. When the Phantom Zone villains arrive on Earth, however, he regains his powers by consuming the energy stored within the Fortress of Solitude. (This is only revealed in the director's cut; the original version has a DeusExMachina transition between Superman staring at a crystal and reappearing fully powered).
* ''Film/XMenFilmSeries''
** ''Film/XMenTheLastStand'' has the "cure," a serum derived from the blood a mutant boy, who can neutralize the powers of other mutants that stand within three feet of him. The cure is offered as voluntary treatment at first, but by the middle of the film, it has been put into plastic darts are fired from plastic weapons powered with compressed air.
** In ''Film/TheWolverine'', [[spoiler:a robotic parasite suppresses Wolverine's healing factor.]]
** ''Film/XMenDaysOfFuturePast'':
*** When Logan first arrives in the past, Charles doesn't have his psychic powers to verify his story or make their mission easier. This is because he's been taking a serum that lets him walk, at the expense of suppressing his telepathy. Considering the HeroicBSOD he's in the middle of, he doesn't mind. The same serum lets Beast look normal with no apparent ill effects, but it has to be taken periodically by both of them.
*** Nullification collars are used in the BadFuture on mutants in the Sentinel-controlled camps.
** ''Film/Deadpool2'': Dangerous Mutants sent to the Iceblock prison are fitted with electronic collars that neutralize their powers (already seen above). Russell can no longer shoots blasts of fire, and Deadpool loses his HealingFactor. This is actually life-threatening in Wade's case, since it also means his cancer is no longer kept at bay and can spread unchecked. [[spoiler:Despite this, Deadpool willingly puts such a collar on at the end to make a genuine HeroicSacrifice for Russell.]]
* In ''Film/TheMummyReturns'', Imhotep finds out that he can't use magic in the temple of Ahm Shere. He was hoping to use it to easily kill the Scorpion King, but realizes that Anubis wishes him to fight as a mortal.
* The "Detention Room" in ''Film/SkyHigh'' cancels out the superpowers of anyone who is in it, obviously as a form of punishment for misbehaving students who are sent there.

* In ''Literature/SwordOfTruth'', the Radahan collars take away the magic of anyone wearing them. Oddly enough, at least in the television version, they aren't immune to magic themselves. In the books the collars could be taken off by magic, but only the Sisters of Light could do it, except for [[spoiler:Zed, who was [[BadassGrandpa so incredibly badass]] that he not only was able to take one off despite not being a Sister, he took it off of himself ''while it was suppressing his magic'']].
* The "muties" from Creator/SheriSTepper's ''Literature/TheTrueGame'' series suppress the gifts of all nearby Gamesmen.
* ''Literature/TheDresdenFiles'': A wizard with a thaumaturgic focus and link to another magic-user can also completely lock down another wizard's magic. Very old and skilled wizards can pull it off without any link at all, but they have to be the tip of the mountain in terms of magical skill and power.
* In ''Literature/TheBlackCompany'' series, a wizard who knows another wizard's true name can basically {{Depower}} them permanently. It also works on [[spoiler:[[TheChosenOne The White Rose's]] inherent AntiMagic]].
* ''Literature/SeptimusHeap'': The Darke Vortex is a spell that can temporarily drain people of their '''Magykal''' powers. It is used by the BigBad to trap Marcia Overstrand.
%%* In ''Literature/{{Animorphs}}'' there is the anti-morphing ray.
* In ''Literature/TheDarkHunters'' series, the magical ability of Were Hunters to [[VoluntaryShapeshifting shapeshift]] can be stopped by ''metriazo'' collars. If they stay on, however, the Were Hunter will eventually explode from the pent-up magick.
* ''Literature/WildCards'':
** The Trump Card virus, developed by Dr. Tachyon, is meant to cure Xenovirus Takis-A (colloquially known as the setting's eponymous Wild Card). Unfortunately, it is only about 5% effective, and itself lethal in about 30% of attempts. Not surprisingly, most of those who tried it were jokers rather than aces, and even few of those would risk it. And a successful cure can also spell the death of the former wildcarder if his powers kept him alive.
** Mai Minh, the Vietnamese Ace healer, can permanently reset wildcarders back to nats. While no Aces were known to ask for healing, she would possibly reset powered jokers and joker-aces.
** Croyd's personal strain of the Wild Card during his Typhoid Croyd period is this trope mixed with mass empowerment, being a forced reroll in the setting's SuperPowerLottery. It can turn anyone to any wildcarder - nat, joker, deuce or ace to carrier, Black Queen, joker, deuce or ace. From ace to joker, deuce or Black Queen is this trope in permanent or lethal form.
** The Astronomer lists the ability to suppress a psychic ace (and thus almost anyone) among his powers. When opposed by Cordelia Chaisson and Demise, he finds out that suppressing only one of them at a time isn't enough...
* In Creator/KurtVonnegut's short story "Harrison Bergeron", people with above-average intelligence (i.e. those who can retain a coherent train of thought for more than 10 seconds) must, by federal law, wear headphones that, every 10 seconds, transmit an extremely loud noise to shatter their train of thought. Also, above-average beauty must wear ugly masks, above-average strength must wear weights, etc. The story shows the logical conclusion of "everyone must be equal."
* The ''Literature/PerryRhodan'' universe has a variety of devices that counter or dampen psionic powers either on purpose or as a side effect of their normal operation, from actual traps and prisons that negate such powers inside a given area to relatively common [[DeflectorShields force fields]] that they cannot penetrate (usually a painful experience for teleporters in particular). Justified in this setting by these powers and much of its advanced technology ''both'' invoking fundamentally the same hyperspace physics and energies, which can then naturally end up interfering with each other as the plot demands.
* The staff at the [[OrphanageOfFear orphanage]] in Creator/JohnCWright's ''Literature/ChroniclesOfChaos'' have been carefully selected to nullify the abilities of each of the orphans. This allows them to impose a RestrainingBolt on each one.
* ''Franchise/{{Mistborn}}'':
** Forcing a Mistborn to burn aluminum causes all of their other metal reserves to be consumed almost instantaneously, leaving them as helpless as a normal human.
** Likewise, an Allomancer can burn chromium to evoke this effect on another Allomancer through touch. According to WordOfGod, this metal remains undiscovered as of ''Literature/TheAlloyOfLaw''.
* In Creator/OrsonScottCard's little-known ''Literature/HartsHope'', the hero character is explicitly born ''as'' a PowerNullifier, because the BigBad is a supremely powerful magician (having, amongst other things, [[DidYouJustPunchOutCthulhu enslaved the kingdom's gods]]).
* In ''Literature/TheWheelOfTime'' series, it's separating a channeler from the True Source. It's called "gentling" when done to a man, "stilling" when it's done to a woman; the gender-neutral term is "severing". It is possible to reverse the process, but it only works completely if the person restoring the connection is of the opposite sex of the person who was severed, otherwise their channeling strength will return at a greatly reduced capacity. More temporary "shielding" is possible to cut channelers off, and certain places such as ''stedding'' and the city of Far Madding are permanently shielded.
* ''Literature/TheShapeshifter'' has one of these with a built in ExplosiveLeash [[spoiler:implanted in the back of the COLA's skulls.]]
* Grey Murphy of the ''Literature/{{Xanth}}'' series has the power to nullify magic in any target he chooses, or increase a subject's magical talents or properties through a "rebound" effect.
* The prize-winning series ''Way Home'' by Vladimir Zykov features both [[RestrainingBolt magical slaves' collars]] and the combinations of those with this trope, using AntiMagic, known as "black collars". One of the protagonists [[spoiler: survives being put into one, manages to break it]] and learns to break them on others.
* Philip K. Dick's classic novel ''Literature/{{Ubik}}'' is about employees of an entire agency of {{Power Nullifier}}s. They are a necessary service, since telepaths and other people with potentially dangerous PsychicPowers are commonplace in the setting.
* In ''Literature/ShadowOps'', anyone who can use magic can Suppress another magic-user's power. This is integral to controlling magic users, and Suppressing someone in the middle of, say, flying, can have nasty consequences. While other branches of the US military actively use their magic offensively in the setting, the US Marine Corps uses "Suppression Lances" that consist of squads of magic-users whose sole job is to Suppress enemy magic-users and kill them with conventional weapons.
* Alexia of ''Literature/TheParasolProtectorate'' is a [[TheSoulless Preternatural]], which allows her to revert [[OurVampiresAreDifferent vampires]] and [[OurWerewolvesAreDifferent werewolves]] to their mortal states for as long as she is touching them and [[OurGhostsAreDifferent exorcise ghosts by touching their remains]]. [[spoiler:[[KillItWithFire If not properly disposed of]] and ''especially'' when mummified, the remains of a preternatural can have this same effect over a slowly-increasing area. This phenomenon is responsible for the godbreaker plague.]]
* In Vadim Panov's ''Literature/SecretCity'': Mages abdicating from their Great House and joining Galla's Heresy forfeit their and their children's magic in favor of a single effect, Galla's Sacrificial Tentacle.
* In Miloslav Knyazev's ''Full Set'' series:
** An archmage uses a power nullifier device of possible pre-war origin to temporarily shut down an opposing sorceress' external power source and [[spoiler:is cut down by her muggle husband with a mythril sword.]]
** A dragon female uses an anti-dragon amulet of unknown origin during a duel with an unwelcome male dragon suitor. Both male and female are forcibly reduced to their humanoid form, which allows her human and elven allies to kill the male. Later research shows the amulet inscription to say "temporary" without a frame of reference, which may mean centuries for dragons.
* In V. Ivashchenko's novels across all settings, various sides in various conflicts will use both stationary and mobile means to capture and detain mages. The ''Black Earl'' series describes a holding cell in an elven castle and forged restraints (collar, handcuffs, manacles) used by human law enforcers.
* A variation in Creator/SergeyLukyanenko's ''[[Literature/NightWatch Last Watch]]'' is an artifact called the Schrödinger's Cat, which takes the form of a furry collar with teeth. Any use of magic causes the Cat to kill the wearer. Only the Other who places the Cat on the neck can take it off. It doesn't prevent magic from being used ''on'' the wearer.
* ''Literature/ForeverGate'': The gols use bronze collars to prevent humans from using their innate ShockAndAwe powers. They are refered to as "bronze bitches" by said humans.
* ''Literature/TheQuestOfTheUnaligned'': The city of Tonzimmiel is surrounded by a force field which strips the magic from anyone who passes through it. Originally built to make the city a safe haven from the Magocracy that rule the surrounding country of Caederan, 600+ years of the field's effects have caused Tonzimmelians to cease believing in magic altogether.
* ''Literature/JourneyToChaos'':
** ''Literature/AMagesPower'': There are runes which are known as "prison runes" because they are used to prevent criminal mages from using their powers to escape.
*** [[spoiler:Tahart hides them in Annala's maid uniform to make her unable to resist him.]]
*** [[spoiler:When Eric is arrested, a metal collar is snapped on him to prevent him from attacking the officers.]]
** ''Literature/LoomingShadow'' and ''Literature/ManaMutationMenace''' feature "Ordercraft collars" that are primarily used on elves to shut down their innate chaotic abilities.
* ''Literature/StarWarsExpandedUniverse'' has a living version of this: Ysalamiris, small, furry reptilian creatures. Their predators are force-sensitive, so they evolved the ability to create a forceless bubble for about 10 meters around them. Imperials took to trying to create Ysalamiri harnesses that they could wear as anti-Jedi measures.
* ''Literature/TheHollows'' has "zip strips", a durable zip tie that can be strapped to a Ley Line Witch's wrist or ankle and severs their contact with ley lines until it is removed, rendering them powerless. Rachel occasionally gets grappled by her opponents and has one of these tied on to amp up the tension, and she herself later uses them against opposing witches.
* In ''Literature/SuperPowereds'', this is Dean Blaine's ability, which works at a certain distance and is entirely selective, meaning some Supers near him can use their powers and some might not be able to. The ability is perfect for a dean at a university with dozens of Supers. In the first novel, he awesomely uses it to negate the ability of a [[PeoplePuppets puppetmaster]], who tries to calm him down, and punches him out with a single hit. In addition, there's also a special headgear designed to keep the person wearing it asleep, which, effectively, negates any active power. It doesn't negate abilities like SuperToughness or a HealingFactor, though.
* In ''Literature/TheGirlFromTheMiraclesDistrict'', Nikita has a spinal implant that helps control her adrenaline levels and thus stops her from HulkingOut, effectively bringing her down from an unstoppable creature of doom to a slightly enhanced human. She wears it willingly, as she despises this side of herself.
* There is a short story in Aimee Bender's book "The Girl in the Flammable Skirt" wherein two teenage girls with [[BlessedWithSuck elemental powers that transform their hands to ice and fire]] act as nullifiers to each other when their hands touch.
* In ''Literature/TheWitchlands'', the Hell-Bards have collars that stop people wearing them from using active witchery[[note]]For example, they stop Vaness from using her ExtraOreDinary powers, but Safi's a LivingLieDetector regardless of whether she has the collar on[[/note]]. As their job is to hunt down rogue witches, this is a rather useful gadget.
* Daniel Arenson's ''Literature/DragonsOfRequiem'' universe features several nullifiers used against both the heroes and the villains. The earliest introduced being the Red Stones which nullify any magic in their vicinity. For the [[ShapeShifting Vir]] [[OurDragonsAreDifferent Requis]] this means lose of their ability to shift into dragon form, and instant reversion to human form should they already be shifted.

[[folder:Live-Action TV]]
* ''Series/OnceUponATime'':
** Rumplestiltskin gives Regina a shapeshifting spell so that she can [[KingIncognito mingle with her subjects and learn what they think of her]]. The disguise prevents her from using magic and cannot be removed by anyone but Rumplestiltskin.
** An organization of [[TheWitchHunter Witch Hunters]] "scientifically" nullify magic by injecting people with metals and nanomachines. Although it's later revealed that [[spoiler:Peter Pan was stringing them along, and their tools weren't really the WeirdScience they thought they were. So it was actually magical Anti-Magic at work]].
* There's a spell in ''Series/{{Charmed}}'' that can depower a witch for as long as the caster lives, though it was never used by the protagonists due to being ''very'' dark magic (the main ingredient is a fresh human heart).
* In ''Series/MutantX'', tags (called Subdermal Governors) bolted into the back of the neck were used to nullify mutant powers, though it seems more to torture them when they try to use them than to truly nullify the powers. It's mentioned that a {{Technopath}} has secretly disabled her Subdermal Governor the moment it was put into her and hasn't given her captors a reason to try to test it.
* ''Series/BuffyTheVampireSlayer'': In the episode [[Recap/BuffyTheVampireSlayerS3E12Helpless "Helpless"]], Buffy, as part of a test by the Watchers' Council on her eighteenth birthday, is hypnotized and Gles is forced to inject a regimen of drugs into her that suppress her Slayer strength.
* ''Series/{{Heroes}}'':
** The mysterious Haitian has, in addition to memory erasing, the power to suppress other people's powers around him. [[FridgeLogic Somehow, Peter is able to copy this ability. With his own power.]] It's implied that the power requires some conscious effort, though, as he is demonstrated at having trouble negating powerful abilities for a long period of time.
** The Shanti virus and some pills used occasionally by the Company suppress powers. It should be noted that the Shanti virus eventually kills the infected.
** The characters captured by Nathan Petrelli's goons have a device taped to them that sprays some sort of drug into their nose. It weakens them enough to the point they can't focus enough to use their power.
** The second eclipse completely nullifies everybody's powers. It's stronger than the Haitian's power, as it reduced Daphne to a crippled state, while she was able to walk around the Haitian. Claire also starts dying of common bacteria, due to not having an immune system from her HealingFactor. %% Do not argue about plot holes here. Those go on the series' headscratchers page. %%
** Maya and Alejandro Herrera. The latter's power is the ability to cancel out the former's uncontrollable poison emission.
* In ''Series/TheFortyFourHundred'', Jordan Collier's ability is to depower others by removing the [[{{Phlebotinum}} promicin]] that gives them their powers.
* In ''Series/{{Smallville}}'', blue kryptonite causes Kryptonian powers to disappear, but it needs skin contact to work. Red sunlight, magic, and various alien devices can also take away Clark's powers. This case is notable for having a guy who DID use it to [[IJustWantToBeNormal lead a normal life]]. It later bit him in the ass.
* ''Series/StargateSG1'' has the Anti-Prior device the team cooked up against the Ori. It emits an inaudible sound that makes Priors unable to use their psychic powers; however, both Damaris and [[spoiler:Daniel Jackson/Merlin]] were able to overcome it given sufficient time.
* The Rada'Han is a collar in ''Series/LegendOfTheSeeker'' used to nullify a person's magical ability. In one case, it was used to prevent a cursed person from turning into a monster. The Pristinely Ungifted are rare individuals completely unaffected by magic. When one is first introduced, she is able to walk through what is, essentially, a magical minefield as if it wasn't there.
* In ''Series/PainkillerJane'', [[DifferentlyPoweredIndividual neuros]] can be rendered harmless by "chipping" them with a special gun that implants a control chip into the back of their heads, counteracting their abilities. [[spoiler:It doesn't work on advanced neuros, though]].
* In ''Series/StarTrekDeepSpaceNine'', the Obsidian Order had a prototype device that would prevent a [[ShapeShifter Founder]] from returning to their natural gelatinous state, with potentially lethal results for the changeling if the device is left on for extended periods.
* In the final season of ''Series/{{Misfits}}'', Alex receives the power to remove other people's powers by [[BlackComedyRape having sex with them]]. [[spoiler: While Alex is under the influence of a power-reversing drug, he discovers that the removed powers are stored inside him by accidentally giving them to someone he hooked up with.]]
* One of Zin's fugitives used a ray gun style device on Cole in ''Series/{{Tracker}}'', nullifying his Cirronian abilities until Mel discovered she could power him back up.
* ''Series/{{Supernatural}}''
** After Castiel absorbed the souls of Purgatory, he was capable of nullifying the powers of his enemy, Raphael, who was an Archangel.
** Eve, the Mother of All Monsters, was able to suppress the powers of Castiel due to being older than Angels.
* ''Series/HeroesReborn2015: Tommy, like his uncle and grandfather, nullifies other evos' abilities. Unfortunately, it took his mother Claire's HealingFactor, causing her to die giving birth to his sister and him.
* In ''Series/{{Powers}}'' Triphammer develops the technology to nullify Powers abilities.
* In the ''Series/AgentsOfSHIELD'' episode [[Recap/AgentsOfSHIELDS2E2HeavyIsTheHead "Heavy is the Head"]], Fitz and Mack modify one of Fitz's old designs to act as a power nullifier for the VillainOfTheWeek, ElementalShapeshifter Carl Creel.
* In the Series/{{Arrowverse}}, there are a number of means for dampening metahuman abilities. They usually take the form of a collar or handcuffs. They have been shown to exist on at least three worlds ([[Series/TheFlash2014 Earth 1]], [[Series/CrisisOnEarthX Earth-X]], and [[Series/{{Supergirl}} Earth 38]]). Some metahumans are strong enough to fight through the dampening effects. Some facilities also come equipped with dampening generators (e.g. Iron Heights Penitentiary, A.R.G.U.S. headquarters). In one case, Ray Palmer develops specialized nanites that, when injected into a speedster, sap his speed, although a skilled speedster is able to vibrate his body to get rid of them. It should be noted that these methods typically only affect metahumans. Magical abilities and alien powers are immune.

[[folder:Tabletop Games]]
* ''TabletopGame/HeroSystem'':
** A power is devoted explicitly to this, called Drain, which reduces the affected power temporarily (or possibly permanently).
** There is also Suppress, which is similar to Drain except Drain "damages" a power or characteristic and it automatically heals over time, while Suppress reduces the power only as long as the Suppress is maintained.
* ''TabletopGame/DungeonsAndDragons'':
** The spell "Mordenkhainen's Disjunction" can strip magic permanently from magic items. Also fits this trope in that, if a spellcaster successfully strips the power from an Artifact-level magic item (which has very low odds to even work unless the character has an obscenely high caster level), the caster himself must make a saving throw or permanently lose all magic-related abilities and spellcasting. Fail the saving throw, and absolutely nothing (not even somebody else casting the ultra-broken "Miracle" or "Wish" spells) can restore the caster's magic. And just in case you didn't think the rules were already stacked to tell you casting Disjunction on an Artifact is a Very Bad Idea, there's also a 95% chance that some god, demon or other ludicrously powerful being connected to the Artifact will show up to punish the caster.
** There exist an expensive item, anti-magic shackles, for restraining magic-users.
** Some Edition 3.5 spells can suppress or remove supernatural abilities. "Trait Removal" or "Spurn the Supernatural" are temporary, while "Expunge the Supernatural" is permanent and can't be dispelled (but is high level and costly).
* Power Nullifiers are known as "pulsing" effects in ''TabletopGame/SenZar'', and they're even more feared than in most other games, because of ''[=SenZar=]'''s munchkin-friendly design.
* ''TabletopGame/LejendaryAdventures''. Morben's Supernatural Shackles would completely prevent the victim from using any kind of magic, including magical items.
* ''TabletopGame/TheDarkEye'' has the substance of banedust as well as some divine rituals to permanently drain the magic ability of a person, used frequently to punish criminal wizards. [[Main/ArmorAndMagicDontMix Enchainments of iron]] serve well as a temporary version.
* In the ''TabletopGame/SavageWorlds'' setting, Necessary Evil, the V'sori utilize nullifier technology to not only remove any and all superpowers from those they are trying to suppress, but to weaken them significantly beyond that point. In the lore, they used this to capture and kill most superheroes in the world, but they are known to use this to capture, imprison, or execute other superpowered beings as well, including the [=PCs=].

[[folder:Video Games]]
* In ''VideoGame/CityOfHeroes'', the Bio-Energy Feedback Inducer is a power-draining weapon used by the "Sappers." It works by [[ManaDrain draining your endurance]], which all powers need to operate. EMP and electrical powers can do this as well, but not drain you completely in a single hit like a Sapper can.
* ''VideoGame/{{Disgaea}}'':
** Yukimaru's special ability in ''VideoGame/Disgaea2CursedMemories'' has a chance to inflict the Amnesia Status, which seals specials.
** The cockatrice class ''VideoGame/Disgaea3AbsenceOfJustice'' has this as its innate evility, but they have to stand next to the enemy to make it work.
* ''VideoGame/FireEmblem'':
** A recurring boss in ''Fire Emblem: Blazing Sword'' is a Magic Seal named Kishuna. As his class name implies, he negates all magic in a 15-space radius of himself. [[WhatKindOfLamePowerIsHeartAnyway It's all he can do]], but since his speed is insane it can take some time to kill him.
** The skill "Nihil" / "Mikiri" in the [[VideoGame/FireEmblemJugdral Jugdral]] and [[VideoGame/FireEmblemTellius Tellius]] sagas. In the Jugdral games, it nullifies all enemy Critical Hit-based, and Special Sword skills; in the Tellius games, it negates all enemy Battle skills. The Tellius games have in addition the Skill "Parity", which has the same effect but extended to the Skill's owner as well, and also negates both the skill's owner and his foe's support and terrain bonuses.
* ''VideoGame/GuiltyGear'' has Sol's headband. It's technically a ''PowerLimiter'', but it makes him so weak his fire magic is completely nullified. Unless he compensates with an artifact that boosts ''specifically'' fire magic.
* In ''VideoGame/GuildWars'' Mesmers can drain an enemies energy, interrupt spells that are being cast and even entirely disable spells from being used for a time.
* ''VideoGame/WorldOfWarcraft''
** All classes have some form of a silence or interrupt effect. The first prevents the target from casting any spells until it expires, the other interrupts a spell that's being cast and prevents them from casting any spell of the same "school" e.g. interrupt a fireball and it stops them casting any fire spell. Due the devastating nature of being locked out like this for many classes (shadow priests until recently had zero non-shadow offensive spells) the duration of the silence or lockout is measured in a scant few seconds.
** Anub'Rekhan is a boss notable for having an area of effect and particularly extreme PowerNullifier. When he casts it anyone near is unable to cast any spell, use any ability, or even just use a normal attack.
* ''VisualNovel/TokimekiMemorial'':
** In ''Tokimeki Memorial 2'', when Sou-Banchou, the leader of Hibikino Town's {{Delinquents}}, turns into his [[TurnsRed Giant Form]], he gains the "Chou-Gankiri" (Super Insight) ability, which nullifies your [[LimitBreak Sports Club Hi-Ougi]] should you have one.
** In ''Tokimeki Memorial 4'', the Skill "Heart Unlocking Technique" / "Kokoro no Kaijoujutsu" negates the girls' negative Skills, such as Satsuki's [[WellExcuseMePrincess "Noble" / "Kouki"]], and Tsugumi's [[{{Tsundere}} "Tsun"]] Skills.
* ''VideoGame/BlazBlue'':
** Hakumen's Nox, Ookami, has this ability, rendered in-game as being able to null out projectiles, and in-story as otherwise immortal characters (Namely Nu-13 and Terumi) don't want it near them.
--->'''Terumi:''' Hey, Hakumen, I ''really'' don't want you touching me with your Ookami, so how about we do this...
** One Celica A. Mercury has the [[PowerIncontinence uncontrollable]] ability to neutralize all seithr in an area around her. As seithr is required to use all ars magus and ars armagus, as well as the Azure Grimoire, she functions as this around most entities. Ragna's right arm and eye go completely numb around her as a result; likewise, the aforementioned Terumi [[OhCrap shits himself]] if he catches sight of her (at the end of his CP Arcade, he screams for Phantom to get him out of there).
** Azrael, one of the three newcomers from ''Chrono Phantasma'', is an interesting case in which he has a Power Nullifier on himself that he ''purposefully'' applied. The Nullifier in question, his Enchant Dragunov tattoos, is activated/deactivated at will, and comes in three levels, with the third level unleashing his true power. The reason for his willing restriction was to draw out the battles he engaged in since fighting at full strength meant opponents who died easily, thus ending fights too quickly.
* In ''VideoGame/{{Prototype}}'', Alex gets injected with a parasite by [[BadassNormal Specialist Cross]] that disables his flashiest powers, though he still has SuperStrength, Super Speed and the ability to disguise himself. He then spends the next few missions working with another scientist on trying to get rid of said parasite, with the final result being that he managed to gain new powers when he comes back.
* ''Franchise/{{Pokemon}}'':
** Disable locks out the target's most recently-used move for a few rounds.
** Imprison locks out any moves the target shares with the user until one of them switches out.
** The move Gastro Acid suppresses the target's ability (unless it's Multityple, Magic Bounce, or Stance Change) as long as they remain in battle.
** Grudge is a TakingYouWithMe version of this trope -- if the user dies the round it's used, the target loses all the use points for the attack that last connected.
** A number of abilities also work as nullifiers. Air Lock and Cloud Nine negate all weather effects. Delta Stream (Mega Rayquaza's ability), Desolate Land (Primal Groudon), and Primordial Sea (Primal Kyogre) keep any moves and abilities that affect the weather from activating except each other, Air Lock, and Cloud Nine.
** Some Pokemon [[ElementalRockPaperScissors type advantages]] cancel out weaknesses. For instance, Dark-types are weak to Fighting-types, but Dark/Ghost-type Sableye is immune to Fighting-types due to its Ghost-typing. From the same generation, the Swampert line is Water/Ground-type and thus the Ground-type nullifies the Water-type weakness to Electric-types.
* In ''Franchise/DragonAge'', the Qunari treat their mages (called Saarebas -- "dangerous thing") even worse than humans (and that's saying something), using magic-nullifying collars to keep them in line. The collars are controlled remotely. Just in case, though, they still cover the mages' eyes and [[MouthStitchedShut sew their mouths shut]].
* ''VideoGame/{{Dishonored}}'' has the Overseers, who wield special music boxes that prevents Corvo from using his powers. However, that does not stop him from blowing their brains out with a pistol.
** In ''VideoGame/{{Dishonored2}}'', the music boxes only get a brief mention [[spoiler:when the Overseers of Dunwall mobilized ''en masse'' to depose Empress Delilah, who as a witch is an affront to their religion.]] As above, they're useless against Delilah's new MechaMooks.
* In ''VideoGame/{{Infamous2}}'', early on in the game, it's revealed that Cole's main goal is to power up to be able to use the Ray Field Inhibitor, which removes the powers of himself and other conduits, including the Big Bad, the Beast.
* In ''VideoGame/{{Xenoblade}}'', Egil has a device called the Apocrypha made in order to disable Shulk's [[LaserBlade Monado]], shorting out its ability to damage his [[HumongousMecha Face Mechon]] along with its other powers.
* In ''VideoGame/XenobladeChronicles2'', Blades absorb Ether energy from the atmosphere and channel it to their Driver to allow both to perform Arts. If the flow of Ether is disrupted in some way, Drivers and Blades become unable to use their powers. The Ardainian Empire uses nets called "stasis webs" capbable of this to capture Drivers and Blades and the Kingdom of Tantal is capable of constructing rooms that drain Ether. These are notably [[NoSell ineffective]] against Artificial Blades like [[RobotGirl Poppi]] who contain an Ether Furnace which generates Ether energy to supplement Ether drawn from the surroundings.
* ''Franchise/TheElderScrolls'':
** ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'' features a remarkably simple way to keep slaves from casting spells: locked bracers enchanted with a small but constant magicka-drain effect. It takes a while to fully work, but once the magicka hits zero it's not coming back up barring magicka potions or removal of the bracers followed by sleep. No magicka, no spells.
** In ''[[VideoGame/TheElderScrollsIVOblivion Oblivion]]'' You can make your own power nullifier by enchanting an item with the [[StandardStatusEffects 'silence']] effect, the trick is getting an enemy to wear it...
* In ''VideoGame/MarioAndLuigiDreamTeam'', Antasma has the unique ability to separate Dreamy Luigi from Mario and imprison him within one of his Antasmunchies. This lowers Mario's stats and leaves him with only his basic jump attack, so freeing Luigi ASAP is in one's best interest, though locating him isn't always an easy task...
* ''VideoGame/TheLegendOfSpyro'' has several artifacts specifically created to drain a dragons ability to use their elements. Dark Gems are the most common, though Gaul has a staff that can do this too.
* ''Videogame/{{MOTHER}}:''
** In ''Videogame/EarthBound'', [[GadgeteerGenius Jeff's]] Counter-PSI unit prevents an enemy from using any [[PsychicPowers PSI]] power for the remainder of the battle. His Neutralizer machine, when used in battle, nullifies all {{Status Buff}}s and nerfs (on both allies and enemies), while his Shield Killer machine nullifies an enemy's shield for the rest of the battle.
** The PSI power "PSI Block" of ''Videogame/EarthBoundBeginnings'' prevents the target from using any of their PsychicPowers for the remainder of the battle.
* ''VideoGame/{{Warframe}}:''
** The aptly named Nullifier unit of the Corpus faction completely prevents the casting of and disables all Warframe powers within the large spherical shield they generate.
** Scrambus and Comba units, also from the Corpus faction, only have the ability to disable certain categories of powers (damage, mobility, etc.), but are much faster and have more health than Nulifiers, and also don't have a visible area of effective, making it easier for them to sneak up on players.
** The Stalker, a rogue Warframe who hunts down players, can dispel certain powers, particularly those that enhance survivability, and stun the players using them in the process.
* ''Franchise/MassEffect:''
** The Damping tech power in the first game acts as a nullified against all of an opponemt's biotic and tech abilities for upto a minute. This usually leaves them vulnerable and defenseless, especially biotics, who can lock you down with Throws otherwise.
** In the third game's multiplayer sections as well as a combat simulator arena in the Citadel DLC, we have the Seeker Plague deployed by the Collectors. This seeker plague similarly renders you unable to use any of your biotic, tech or even combat and defensive powers till you or a squadmate shoots them off you. What is notable is that the Seeker Plague is actually a heavily ''nerfed'' version of the Seeker Swarm from the second game. That Seeker Swarm paralyzed you in stasis for a long time.
** The Stasis biotic ability in all three games does this to an enemy with the added benefit of nullifying his powers too. A highly evolved Stasis even inflicted damage and allowed you to shoot through it at the poor guy. In the franchise lore, a drug called omega-enkaphalin was developed and used to nullify biotic ability long term. The human survivalist group tested it on the naturally biotic asari, didn't use it on Grissom Academy to subdue a bunch of biotic human children as they wanted those biotics intact, and used it against a particularly haughty elitist asari matriarch to embarrass her into obscurity. A different terrorist group attempted to use it against the biotic training facility on Pluto's Gagarin station.
** In ''VideoGame/MassEffectAndromeda'', severing Ryder's connection to SAM nullifies all of his/her abilities as well as damaging Ryder. It takes Ryder's opposite sex twin resetting that connection to bring Ryder's powers back.
* Willo's Deadzone skill from ''VideoGame/{{Paladins}}'' blankets an area in fairy dust that completely nullifies enemy healing within it.

[[folder:Web Comics]]
* Gamma from ''Webcomic/GunnerkriggCourt'' prevents Zimmy's powers from acting up (or at least lessens their magnitude) simply by her presence. But it doesn't work as well when she's asleep -- and she's pretty much Zimmy's only means of controlling her powers. Antimony can play this role for Zimmy in a pinch, but she's nowhere near as strong as Gamma.
* At least one Spellwolf from ''Webcomic/DominicDeegan'' has shown the ability to cast the spell "Null Magic".
* ''Webcomic/TheDreamlandChronicles'': Humans in DreamLand have powers, always including flight, unless they are afraid. The {{pirate}}s exploit this.
* ''Webcomic/TheDragonDoctors'' has Kili's tattoos, when applied to any other shaman than herself.
* The purpose of Agatha's locket in ''Webcomic/GirlGenius'' is to suppress her [[ScienceRelatedMemeticDisorder spark]]. Later in the story, it plays a similar, but different purpose.
* [[Webcomic/EvilOverlordsUnited Max Catnap]] of the ''Webcomic/CrossoverWars'' is a walking literal example of this trope. He has the power to [[BroughtDownToNormal nullify other magical or powerful characters]] by simply touching them.
* In ''Webcomic/{{Spacetrawler}}'', the Ites are uniquely qualified for police work because they emit an anti-telekinesis field.
* In ''Webcomic/{{Kubera}}'', the Sword of Return is a god-level item designed to fight [[OurDemonsAreDifferent sura]]. It inhibits the [[HealingFactor regeneration]] of anything it strikes (specifically, it brings it down to normal human regeneration, which is basically nonexistent), from sura to gods, making them far easier to kill. While most sura and any god could [[OnlyTheChosenMayWield easily wield the weapon]], the problem is that it does the same thing to the ''owner'' as well, and the only way to give up the sword is to die. This makes it a perfect weapon for a human, but every sura who has tried to use it has inevitably died quickly and messily.
* In ''Webcomic/BlackHaze'', [[spoiler:Kielnode Chrishi]] is forced to wear a bracelet that restricts mana usage after he ([[SadisticChoice unwillingly]]) [[TradingBarsForStripes rejoins]] [[TheGovernment the Tower]]. When he asks how long he has to wear it for, he's told until he can be trusted again.
* In ''Webcomic/{{unOrdinary}}'' the people after Seraphina have at least two types of Power Nullifier. First, they have some device transportable by van, that severely weakened the power of the students and at first left [[spoiler:John]] (AllYourPowersCombined) unable to sense others' powers; this one has some kind of time limit. Second, Seraphina was injected with something she was unable to [[TimeMaster rewind]] and that interfered with her other time powers, eventually eliminating them entirely. Her powers haven't returned as of yet, but are theorized to recover once the drug works its way out of her system in a few days.

[[folder:Web Original]]
* In the ''Literature/WhateleyUniverse'', there may not be gizmos that work as power nullifiers (yet), but some mutants (such as Negator and Damper) have that ability. It does backfire somewhat against Tennyo, however, as she actually gets ''more'' powerful with her mutant abilities suppressed; she just starts using the power of the [[EldritchAbomination Class X Entity]] contained inside her.
* In the ''Roleplay/GlobalGuardiansPBEMUniverse'':
** Purge has the power to turn off metahuman powers, but not magic or powers gained through technology.
** Scramble can cause metahuman powers to misfire and not work properly (though they do tend to still work ''somehow'').
* Wiki/SCPFoundation's SCP-514. Whenever in contact with the pigeons' nullifying "aura", every weapon (bombs, guns, tanks, baseball bats, knives, etc.) is rendered completely useless and are even destroyed after prolonged exposure. Even objects not designed to be weaponized like pens were rendered useless if used for violent intent. In addition, the pigeons' ability can completely suppress the negative emotions and intent of all sentient beings, no matter how violent, which makes the capture of SCP-514 nearly impossible.
** Before the reboot, the Foundation stocked and made extensive use of [[http://www.scp-wiki.net/scp-148 SCP-148]], "Telekill Alloy", a metal that nullified psychic powers. People [[WhenAllYouHaveIsAHammer overusing it]] for their SCP entries led to 148 being revised to a metal that nullifies psychic powers... with unacceptable side effects on everyone nearby.
* The intro to ''[[Webanimation/SockSeries Empire of Sock]]'' shows that the only thing the titular hamster's evil powers can be contained by... is a seemingly regular hamster cage.
* In ''Literature/TrintonChronicles'', Elijah's power allows him to nullify a power by [[PowersasPrograms storing it in a crystal]] temporarily.
* ''Literature/{{Phaeton}}'' has zero elements which can be used to negate magic, scramble psychic waves and toggle genes.
* ''Literature/TheLayOfPaulTwister'': Paul Twister]] has "the Twist", the ability to screw up active magic by touch. It's apparently [[PowerIncontinence not under his conscious control]], and he remarks several times [[InformedFlaw (though it's yet to be shown)]] that the Twist is not perfect and doesn't make him invincible against magic.
* Black Cavalier of ''Podcast/RollToBreathe'' can nullify powers with concentration and skin contact, which which is extremely useful in combat. [[spoiler: After Black Cavalier enters the Max Machine, this power becomes a lot more chaotic and can be used at ranged. With concentration Black Cavalier can even steal someone's powers permanently.]]
* In ''Literature/{{Worm}}'', Hatchet Face shuts down the powers of anyone near him.
** Mantellum has this power as well, but only for the sensory aspects of powers. Taylor's bugs don't relay what they sense, and even Contessa's power is shut down [[spoiler:("seeing the path to victory" being a form of clairvoyance)]].
** Grue's darkness interferes with some powers as well, including Shadow Stalker's intangibility and Velocity's SuperSpeed. [[spoiler:After his second-trigger this upgrades to the ability to outright steal powers from anyone inside his darkness, though doing so only shuts down more physically based powers.]]
** More generally, this is a sub-type of the Trump classification of powers.
* ''WebAnimation/{{Dreamscape}}'': The Overlord of Evil's seal stops him from using his powers...as long as he is alive, that is.

[[folder:Western Animation]]
* ''WesternAnimation/AvatarTheLastAirbender'':
** Disruptions in ElementalPowers of the series' Benders occur during temporary meteorological events. [[PlayingWithFire Firebenders]] and [[MakingASplash Waterbenders]] draw their power from the sun and moon, respectively. When solar or lunar eclipse occurs, the affiliated Benders lose their powers for its duration. It's also possible to stop Waterbending for good by destroying the moon through its [[NatureSpirit totemic spirit]], (which, while easier than it sounds in this setting, is not a good idea, as it will enrage the moon's partner, the ''[[MakingASplash Ocean]]'').
** In the series finale "Sozin's Comet", [[spoiler: Aang ''permanently'' does this to Ozai, using energy-bending he learned from a giant Lion Turtle.]]
** BadassNormal martial artist Ty Lee has learned to [[TheParalyzer disable]] the ElementalPowers of Benders by striking {{Pressure Point}}s to block the flow of ''chi'' (resulting in considerable pain for some of her victims). In SequelSeries ''WesternAnimation/TheLegendOfKorra'', Ty Lee's ''chi''-blocking technique is employed by [[AntiMagicalFaction Anti-Bending Faction]], the Equalists. TheLeader of the Equalists, Amon, [[spoiler:claims to be able to permanently remove bending, with the implication he uses the same technique Aang used. In actuality, he's using a form of Bloodbending.]]
* There are two in ''WesternAnimation/DannyPhantom'':
** The Specter Deflector wards off anything ectoplasmic, so if Danny were to turn into his ghostly SuperHero counterpart, he'd get a nasty electric zap.
** The other is the more straightforward version of this trope: the Plasmius Maximus, designed to nullify ghost powers for a good three hours.
* In the animated version of ''WesternAnimation/LegionOfSuperHeroes'' this was Nemesis Kid's power.
* In ''WesternAnimation/XMenEvolution'', Leech's power extends to more than shutting down powers: it can shut down ''anything.'' When he used it to its fullest, a good chunk of the city lost power. Like movie Leech, he can also undo physical mutations, such as Spyke's permanent bone-armor vanishing, restoring his season one appearance until the effect ended.
* ''WesternAnimation/ThePowerpuffGirls'':
** Antidote X, first appearing in "Mo Job" as part of Mojo's plan to permanently remove the girl's powers after he is hired by Princess. It is loaded into a laser and fired at the girl's but never directly hits them. The gun is broken at the end of the episode after the beam is deflected back at Princess.
** It later appears in "Slumbering with the Enemy". Mojo Jojo threw it at the title superheroes in said episode to reduce them to normal little girls, though this [[SnapBack obviously didn't affect subsequent episodes]]. TheMovie reveals that it was initially created to get Mojo out of his OneWingedAngel form, though the girls briefly considered using it on themselves so they would be better accepted without superpowers.
* On ''WesternAnimation/BuzzLightyearOfStarCommand'', Zurg manages to turn off Mira's powers by setting her in a box that disrupts her concentration whenever she tries to use her powers. Since concentration is required, well....
* ''WesternAnimation/GeneratorRex'':
** The title character has [[{{Depower}} permanent]] Power Nullification as one of his primary powers, though considering how [[SuperPowerRussianRoulette powers are handed out]] in the ''Generator Rex'' universe, its not really that threatening except against the few [[OurMonstersAreDifferent EVOs]] with a ComicBook/{{Magneto}}-like ideology.
** Feakins from the episode "Deadzone" exhibits some sort of Nanite deadzone around himself. If Rex is in too close a vicinity to him, his powers don't work.
* An indeterminate variant is used by Lex Luthor on Lord Superman at the end of the ''WesternAnimation/JusticeLeague'' two-part episode "A Better World". What exactly happened to his powers are unknown but he's at least able to be captured and detained by conventional shackles once it's been used on him.
* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'':
** [[EvilOverlord King]] [[DarkIsEvil Sombra]] from the [[Recap/MyLittlePonyFriendshipIsMagicS3E1TheCrystalEmpirePart1 season]] [[Recap/MyLittlePonyFriendshipIsMagicS3E2TheCrystalEmpirePart2 three]] premiere could create dark crystals that could negate a pony's magic, from embedding them into Shining Armor's horn to keep him from casting ''any'' magic, to a [[spoiler:trap keeping Twilight from teleporting outside of it with the [[MacGuffin Crystal Heart]]]].
** The "[[Recap/MyLittlePonyFriendshipIsMagicS4E24EquestriaGames Equestria Games]]" use disabling spells ([[{{Magitek}} which look like airport metal detectors]]) that unicorns must pass through to prevent cheating in the events.
** In "[[Recap/MyLittlePonyFriendshipIsMagicS5E2TheCutieMapPart2 The Cutie Map Part 2]]", the BigBad's cutie mark equalizer dampens the special talent of any character hit by it and removes their cutie mark. Not only does it rob them of ''any'' ability beyond even the most base level ability of a pony, but it even mildly affects their personality. Pinkie Pie becomes much less fun-loving and Applejack becomes unable to use [[BuffySpeak Western...isms]].