Shane Gooseman, the Super Soldier from Adventures of the Galaxy Rangers. He towers over the other three (and, at 19, is probably not finished growing, either!), and can easily take the most damage. Definitely a Class 3, as he comments in "One Million Emotions" that his kind can only get "angry and mad," but was seen in "Supertroopers" being the only one of his kind that questioned his role as a Super Soldier.
Another Galaxy Rangers example: Buzzwang. While he may not be programmed for combat, it is possible that he, being a robot, is stronger then the average human.
Her original design was a large, muscly man- this is one of many Lampshades hung in "The Ember Island Players," where her part in a play is inexplicably filled by a burly, muscled man. (Toph is delighted.)
In the first half of Sequel SeriesThe Legend of Korra, AsamiSato fills this role. A cunningBadass Normalmartial artist who packs a taserglove, she's somewhere between a type 2 and a type 5; although willowy (and decidedly more femmethan Korra), she's the second tallest of the central cast. Conversely, barrel-chested earthbender Bolinwhose character design is based off of the original concept for Toph, and who looks more like he'd fit the roleis actually The Heart. Later seasons swap the dynamic: Bolin Takes A Level In Badass by learning lavabending, which gives him massive AOE attacks, emphasizing his raw power and making him the groups hardest hitter. Meanwhile, Asami's role becomes more focused on her being Korra's confidante and emotional support (and eventual love interest).
Trevor Belmont from Castlevania is a Class 5 Big Guy for Power Trio being the most combat inclined as a Vampire Hunter. Its especially evident in the second season when Alucard and Sypha like a couple of nerds have to hit the books and magically trap Draculas castle all while Trevor goes One-Man Army on the The Legions of Hell to defend them while they work because combat is his specialty. Though Trevor can overlap with The Leader with all the orders he gives.
Wolf Bronski and Marsala from Exo Squad embody two different styles of the trope. Bronski is the team's Boisterous Bruiser, wielding a ground-support E-frame with powerful weapons and being the show's main source of levity. Marsala is the team's Genius Bruiser, a Neosapien working for Exofleet and the most physically imposing of Able Squad, but prefers using more strategic approaches and subversion to undermine Phaeton's regime.
In Futurama when muscle or a degree of inhuman dexterity is required, Bender can be counted as a Class 5 Genius Bruiser, although he's more cunning than clever. If the problem is just with too many Badass Normal mooks, then Leela will go berserker and kick their butts with her ninja skills.
Gargoyles: While Goliath has the physique normally associated with the character, this is Broadway's function. He might be a little on the chubby side, but he's no less strong or (as one unfortunate mook found out when his gun was effortlessly crushed like a soda can) fearsome in a confrontation.
Wendy from Gravity Falls normally looks like a laid-back teen girl that happens to be Younger Than They Look due to "freak lumberjack genes" leading to an early growth spurt. Those same freak lumberjack genes also give her the power to snap a huge ex-con's arm like a twig and make her very handy with an axe.
Split between Hawkgirl and Superman (plus the Martian Manhunter when the writers remember that he can do more than just phase).
June from KaBlam!, not in terms of size, but she's definitely the toughest character.
Rosa from Kid Cosmic is the toughest and strongest member of the team, owing to the powers that her Cosmic Stone brings her. It's a bit of an unusual example, because she's a 4-year-old.
The show King Arthur & the Knights of Justice was an interesting example, because it starred a team of football players temporarily taking the place of the Knights of the Round Table, it was unique in having about five big guys (Lineman) who were essentially interchangeable from one story to the next.
Nathan Explosion of Metalocalypse is a Class 3 if there ever was one- his growling voice, immense size, and general reputation of brutality hides the fact that, at heart, he's something of a marshmallow. Who loves kitties. And his father. And Disneyland.
Rainbow Dash from My Little Pony: Friendship Is Magic. She's as strong as Applejack, very athletic, and far quicker to request a direct, physical solution than any other team member. She also happens to be pretty dense and, to top it off, she's the Spirit of the Element of Loyalty.
The male half of the SilverHawks' Steel Twins, William "Steelwill" Hart, is a good example.
Air Enforcer is this to the Skysurfer Strike Force, being the biggest, strongest member with the most weapons.
Super Noobs: Memnock and Zenblock are the only two alien members of the Super Noobs team that consists of six members and both of them fit the role of the big guys due to their size. Zenblock is mainly a class 1 with some elements of class 2. Memnock is definitely a class 2.
Buck Tuddrussel of Time Squad punches first and asks questions later. Could even be categorized at some points as Dumb Muscle.
Total Drama: DJ is the big guy of the first three seasons. He is of the Class 2 variety due to his love of animals, sensitive personality, and his interests. Owen was also the big guy whenever he was on the opposite team to DJ (like in Island), but was more of a Class 3 type, given his excitable and enthusiastic character.
The Transformers: Prime team has their own Bulkhead. He's a veteran soldier with some "dirty work" in his history, but still has a gentle side.
In the original Transformers, Ironhide fits this quite well for a group much larger than 5, although there's certainly a group that's considered more central than others. Also a good example of this trope from the original would be Brawn, who despite actually being SMALLER than most of the Autobots, otherwise fits this trope extremely well.
Autobot gestalts, such as Superion, typically fall into this role by default.
Brock Samson from The Venture Bros. is a Class 3. He's got a hard exterior but he genuinely cares for Hank and Dean.
Kano from the "original" Team Venture.
Boo Boom! The Long Way Home: Being a horse, Boldsteed is easily the biggest and strongest member of the group. He frequently carries all his teammates at once, and is the most useful in a fight. He is however of the Gentle Giant varity, frequently acting as the voice of reason in the group.
Jackie Chan Adventures: Tohru starts as the Brute for the Dark Hand in Season 1, before he makes a HeelFace Turn and becomes a type 2 for the Chan family. Mixes in type 4 once he becomes Uncle's apprentice and starts learning chi magic.
Xiaolin Showdown: Clay is a Gentle Giant from Texas who's polite, even-temepered, every inch the Southern gentleman...just don't mess with his friends...or his hat. Then he'll quickly demonstrate to you why he's the Dragon of Earth...unless you're a lady, but he usually finds a workaround for that.