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N
- The Naked Gun:
- The Naked Gun: From the Files of Police Squad!: Vincent Ludwig, a wealthy socialite plotting the assassination of Queen Elizabeth II.
- Naked Gun 2½: The Smell of Fear: Quentin Hapsburg, who's behind the kidnapping of Dr. Meinheimer and plans to have a lookalike endourse his own energy policy.
- Naked Gun 33⅓: The Final Insult: Rocco Dillon, who plots to bomb the Academy Awards.
- Nam Angels: Chard, a former Nazi who's kidnapped a group of American soldiers in Vietnam.
- National Treasure: Ian Howe, who plots to steal the Declaration of Independence to find the Templar Treasure. Ben Gates plans to steal the Declaration before Ian can destroy it.
- National Treasure 2: Book of Secrets: Mitch Wilkinson frames Ben's ancestor Thomas Gates of being a member of John Wilkes' Booth's conspiracy, forcing Ben to find Cibola to clear his ancestor's name.
- Nazi Overlord: Dr. India Eris, who has joined up with the Nazis to make bioweapons for them.
- Near Dark: Jesse Hooker, leader of a ruthless vampire gang.
- Ned Kelly (1970): Superintendant Nicholson, head of the corrupt police department that drove Ned to crime.
- The Negotiator: Commander Grant Frost, the one behind Nate's murder.
- Nekrotronic: Finnegan, a corrupted nekromancer seeking to unleash demons upon Earth.
- The Neverending Story: The Nothing, a force created from the forgotten hopes and dreams of mankind that threatens to erase Fantasia, and by extension, humanity's imagination.
- The Neverending Story II: The Next Chapter: Xayide, an evil sorceress who spreads the Emptiness across Fantasia, leaving its denizens devoid of meaning.
- The Neverending Story III: Escape From Fantasia: Slip, the leader of the Nasties who steal the NeverEnding Story Book and use it to cause chaos in both Fantasia and the real world.
- New Jack City: Nino Brown, a rising crime lord and drug dealer in New York City, who takes control of an apartment complex and capitalizes on the crack epidemic.
- The New York Ripper: Peter Bunch, a duck-voiced madman killing women in New York.
- Nightbreed: Dr. Philip Decker, Boone's Psycho Psychologist who frames him for murders he committed and starts a war against the Nightbreed.
- Nightcrawler: Louis "Lou" Bloom, who is willing to commit any crime to get good footage for the news.
- Night at the Museum:
- Night at the Museum: Cecil Fredericks, Larry Daley's predecessor as head night watchman at the Museum of Natural History. He accepted Larry as a replacement in the first place in spite of Larry's poor resume so he and his co-night watchmen Gus and Reginald could conspire to steal the Tablet of Ahkmenrah, which reinvigorates them at night in addition to bringing to life the museum exhibits, and frame Larry for the crime so they could have a graceful retirement, even if it means robbing the exhibits of their life. Larry ultimately catches up to him and defeats him, but doesn't have Cecil arrested, leading to him becoming a reformed Ex-Big Bad in Secret of the Tomb.
- Night at the Museum: Battle of The Smithsonian: Kahmunrah, Ahkmenrah's older brother. He sees an opportunity to use the Tablet of Ahkmenrah to summon his underworld army to Take Over the World when the tablet arrives at the Smithsonian with the many museum exhibits shipped to it from the Museum of Natural History. Kahmunrah actively opposes Larry's attempts to stop him and save the other exhibits, even threatening Jedediah at one point, and puts together an alliance with Ivan the Terrible, Napoléon Bonaparte, and Al Capone in order to have greater power. Unlike Cecil and Lancelot, Kamunrah never gets a Heel–Face Turn and is soundly defeated for his crimes.
- Night at the Museum: Secret of the Tomb: Lancelot, the museum exhibit based on the famed Knight of the Round Table from Arthurian Legend. He is initially introduced as a new ally who Larry and the other museum exhibits encounter at the British Museum, before becoming convinced the Tablet of Ahkmenrah is the Holy Grail he seeks for Arthur and Guinevere and steals it from Larry before running off into the streets of Britain. His shock at discovering he is not a real person leads to a further Villainous Breakdown until the Tablet beginning to lose the last of its magic, leading the rest of the exhibits to start going inanimate, convinces him to have a Heel–Face Turn, give up the Tablet, and let Larry restore its magic to save them.
- The Night Flier: Dwight Renfield, a vampiric pilot stalking the airfields of America.
- Night Hunter (1996): Ulmer, a Vampire Monarch trying to make sure the eclipse happens properly to continue his species.
- Night of the Demon: Julian Karswell, the leader of a devil-worshiping cult who's using a demon to kill his enemies.
- Night of the Demons (1988): The demon possessing Angela leads the chaos in Hull House.
- The Night of the Hunter: Reverend Harry Powell, a corrupt preacher and Serial Killer who will go to any length to obtain the money hidden by his former prisonmate Ben Harper.
- Night of the Templar: Lord Renault, who masterminded Gregoire's slaying.
- A Night to Dismember: Mary Kent, the latest in a long line of killers in a certain family.
- Night Watch: Zavulon, head of the Dark Others, who wants to make the centuries-long cold war between Dark and Light hot again.
- A Nightmare on Elm Street: Freddy Krueger, an undead child killer stalking the dreams of his killers' children.
- Wes Craven's New Nightmare: The Entity, an ancient evil that's existed in various forms throughout history and has now taken the form of Freddy Kruger.
- Ninja: Masazuka, who is seeking to steal his former master's collection of weapons, and is taking advantage of a corporatist cult to do so.
- No Country for Old Men: Anton Chigurh, a hitman initially tasked with obtaining the money lost in the shootout, but goes rogue and starts killing everyone in his pursuit of the money.
- Noah: Tubal-Cain, who wants to seize Noah's Ark for his tribe of cannibals and rapists.
- Non-Stop: Tom Bowen, who masterminds the plane hijacking in order to prove the lack of safety in American airline security.
- Nope has a mysterious UFO abducting the Haywoods' horses, leading the siblings to try and get photographic evidence of it. While at first believed to be an alien spaceship, the UFO is revealed to actually be a living predatory creature that was eating the horses alive, and the situation goes From Bad to Worse when the beast (dubbed Jean Jacket by OJ) eats everyone at the Star Lasso Experience at Jupiter's Claim...
- Noroi: The Curse: Kagutaba, a demon trying to get itself summoned into the world and whose very spiritual presence is a curse on those around it.
- North to Alaska: Frankie Cannon, who's out to take the group's gold for himself.
- Nosferatu: Count Orlok, a vampire spreading a plague across a German village.
- Nosferatu the Vampyre: Count Orlok reprises his role as Big Bad in this remake by Werner Herzog, only he's officially allowed to be Dracula this time (with "Orlok" was a failed attempt to circumvent copyright). He makes the town of Wismar, Germany, his new hunting grounds and deliberatey seeks to spread the plague (in contrast to the original film, in which his spreading of his disease is incidental).
- Now You See Me: Dylan Rhodes, the Fifth Horseman who's been controlling the Four Horsemen the entire time.
- Now You See Me 2: Arthur Tressler turns out to be the mastermind of the plot targeting the Horsemen.
- Nudist Colony of the Dead: Mrs. Druple, head of a group of zombie nudists who kill religious people.
O
- O Brother, Where Art Thou? has Sheriff Cooley, who pursues Everett's group throughout the movie.
- Oblivion (1994): Redeye, an outlaw trying to take over the town.
- Oblivion (2013): "Sally", the Tet's A.I. who's using clones of Harper and Victoria to eradicate the last of humanity.
- Ocean's Eleven: Terry Benedict, a ruthless billionaire whose casinos Danny Ocean targets for his heist.
- Ocean's Twelve: Terry Benedict again, who forces Danny and his crew to repay the money they stole, and François Toulour, a thief envious of Danny's legendary heist who sold him and his crew out to Benedict and is determined to outdo him.
- Ocean's Thirteen: Willy Bank, who tricks Reuben into investing in his new big hotel-casino and then he takes everything for himself; with Danny Ocean planning to rob it as revenge.
- Old: [[spoiler:The pharmaceutical executive masquerading as a hotel resort manager who's been trapping tourists with different chronic illnesses on the beach in order to study them for medical research.
- Oldboy (2003): Lee Woo-Jin, the one responsible for imprisoning Oh Dae-su for fifteen years; leading him to go on a Roaring Rampage of Revenge.
- Olympus Has Fallen: Kang Yeonsak, a terrorist who leads the takeover of the White House.
- London Has Fallen: Aamir Barkawi, an Arms Dealer supplying weapons and explosives to terrorists and failed states across the globe.
- Angel Has Fallen: Martin Kirby, the mastermind behind the assassination attempt on President Trumbull that Mike's framed for.
- The Ωmega Man: Jonathan Matthias, the leader of the group of albino mutants, "The Family", who has set out to eliminate all traces of civilization; including Robert Neville.
- The Omen: Damien Thorn, the Anti Christ destined to bring ruin to the world.
- On Guard: Philippe de Gonzague, a French 18th century nobleman who's jealous of the wealth of his cousin Philippe de Nevers and kills him to inherit his fortune and marry his wife.
- On the Waterfront: Johnny Friendly, a mob boss running the dockworkers' union whose illegal activities Terry plans to expose.
- Once Upon a Time in the West: Frank, a ruthless mercenary who is tasked with forcing the McBain family off their land. This brings him into conflict with Harmonica, a gunman with a vendetta against Frank.
- The One: Gabriel Yulaw, a former officer of the Multiverse Authority who travels to various parallel universes to kill alternate versions of himself so he can absorb their power and become "the One", with Gabe Law being his final target.
- One Flew Over the Cuckoo's Nest: Nurse Ratched, the abusive, domineering nurse who runs the state hospital with an iron fist. At least until Randle shows up.
- One Hour Photo: Seymour Parrish, a mentally disturbed photo developer who obsessively stalks the Yorkins family.
- One Man's Justice: Agent Karl Savak, a corrupt FBI agent selling weapons.
- Ong-Bak: Komtuan, a crime boss who has the head of the sacred Buddha statue stolen from Ting's village.
- The Open House: An unnamed Serial Killer terrorizing people at open houses.
- Orphan: Esther Coleman, a woman with dwarfism posing as a child who plans to kill her latest adoptive family so she can have John to herself.
- Othello: Iago, who drives Othello insane by convincing him his wife is cheating on him.
- Out of the Furnace: Harlan DeGroat, a crime boss responsible for the death of Rodney's brother, Russell.
- Gangster VIP: Ueno, head of a Yakuza clan trying to destroy Goro's.
- The Outlaw Josey Wales: Captain "Redlegs" Terrill, a Union guerrilla-turned-soldier who killed Josey's family and spends the film pursuing him.
- The Outlaw Michael Howe: Peter Septon, corrupt governor of Van Diemen's Land.
- Overlord (2018): Captain Wafner, the commander of a Nazi garrison oppressing a French town, and supervises human experimentation on the villagers.
P
- P-51 Dragon Fighter: Dr. Heinrich Grudun, a Nazi occultist setting dragons upon the Allies.
- Pacific Heights: Carter Hayes, Patty and Drake's new tenant who torments them in order to get their property for cheap.
- Pacific Rim: The Progenitors, a group of aliens who keep setting kanji on Earth to destroy the humans.
- Pan's Labyrinth: Captain Vidal, a Francoist soldier bent on crushing the leftist revolutionaries.
- The Passion of Joan of Arc: The Bishop of Beauvais, a corrupt clergyman out to make sure Joan of Arc recants or dies.
- The Passion of the Christ: Joseph ben Caiaphas, High Priest of the Temple of Jerusalem, is the primary agent calling for the execution of Jesus, taking great pleasure at seeing him scourged.
- The Patriot (2000): General Lord Charles Cornwallis, the highest officer in the British Army, leading the Southern theater against the Continental Army, and Colonel William Tavington, who systematically hunts down Martin's guerillas; with Martin's personal objective being to kill the latter.
- Peeping Tom: Mark Lewis, the Villain Protagonist, who kills women while photographing their death cries.
- Peppermint: Diego Garcia is the son of a Cartel chief, responsible for much of the LA drug trade. He directly ordered the hit on protagonist Riley North's husband, and drives the villainous manhunt against North.
- Phantasm: The Tall Man, a Humanoid Abomination acquiring corpses to make into his slaves.
- Phantom of the Paradise: Mr. Swan, the devil-worshipping CEO of Death Records who steals Winslow's music and has him sent to prison; driving him to become the Phantom and exact his revenge.
- The Phenix City Story: Mob boss Rhett Tanner, who runs the Poppy Club and all the organised crime in Phenix City, is the main antagonist and directly or indirectly responsible for all the bad things that happen in the movie.
- Phenomena: Patua Bruckner, a Serial Killer offing girls near a boarding school.
- Pieces: The Dean, who is killing random women for their parts.
- The Pink Panther:
- The Pink Panther (1963) has Sir Charles Lytton, the identity of the master thief known as the Phantom who is out to steal the Pink Panther jewel.
- A Shot in the Dark has Benjamin and Dominique Ballon, Madame Lefarge, Simone [[BigBadEnsemble and Pierre, all of whom are responsible for the string of murders Clouseau is trying to solve. They're later joined by Commissioner Charles Dreyfus after his Sanity Slippage]].
- The Return of the Pink Panther has a Big Bad Ensemble between Lady Claudine Litton, who framed Sir Charles for the theft of the Pink Panther, Colonel Sharki, who uses the theft as an excuse to conduct mass arrests of his political opponents, and Chief Inspector Charles Dreyfus, who continues his attempts to kill Clouseau.
- The Pink Panther Strikes Again has Charles Dreyfus on his own as he becomes a criminal mastermind with an army of assassins at his disposal to kill Clouseau.
- Revenge of the Pink Panther has Philipe Douvier, the head of the French mob who puts a hit on Clouseau.
- Curse of the Pink Panther has Bruno Langlois,a mafia boss who orders the assassination of Sleigh.
- Son of the Pink Panther has Hans Zarba, who kidnaps Princess Yasmin.
- The Pink Panther (2006) has Yuri, the murderer of Yves Gluant who Clouseau and Dreyfus are trying to catch.
- The Pink Panther 2 has Sonia Solandres, who stole the Pink Panther under the guise of the Tornado.
- The Pit: Jaime Benjamin, a Creepy Child who feeds people to monsters.
- The Pit and the Pendulum: A Big Bad Duumvirate of Elizabeth Medina and Doctor Leon, who conspire to drive Nicholas Medina insane so they can take his fortune.
- Plan 9 from Outer Space: Eros, a Well-Intentioned Extremist alien setting zombies on humans to prevent a sunlight bomb.
- Plane: Datu Junmar, the Filipino militant leader who kidnaps the passengers of Brodie Torrance's plane in order to secure ransom from their families.
- Planet of the Apes:
- Planet of the Apes (1968): Dr. Zaius, who continuously plots against Taylor in order to maintain the Apes' prejudiced views towards humans and prevent them from repeating their mistakes.
- Beneath the Planet of the Apes: A large Big Bad Ensemble consisting of General Ursus, who leads the invasion of the Forbidden Zone, and Mendez XXVI, the mutant clut leader who holds the Alpha-Omega bomb.
- Escape from the Planet of the Apes: Dr. Hasslein, who actively seeks to kill Cornelius, Zira and their child in order to try and prevent the coming of the Planet of the Apes.
- Conquest of the Planet of the Apes: Governer Breck, who's determined to crush the ape rebellion and preserve the status quo.
- Battle for the Planet of the Apes: A Big Bad Ensemble that consists of Governor Kolp, the leader of the mutated humans who seeks revenge against the apes that they blame for humanity's downfall, & General Aldo, who plots to overthrow Caesar and intends to rule ape society with an iron fist.
- Planet of the Apes (2001): General Thade, who's out to end mankind.
- The Apes sub-series starring Caesar:
- Rise of the Planet of the Apes: Steven Jacobs, the head of Gen-Sys Laboratories who pushes the mass-production of ALZ-113 despite warnings over the potential disaster it could cause, and helps lead the failed attempt by police to neutralize Caesar and the other apes.
- Dawn of the Planet of the Apes: Koba, who betrays Caesar and takes over the ape colony; leading them in taking over San Francisco.
- War for the Planet of the Apes: Colonel McCullough, the one leading Alpha-Omega against Ceasar and his tribe.
- Platoon: Staff Sergeant Bob Barnes. While the larger conflict is with the VC, Barnes is the true evil force of the story and drives the conflict within the platoon itself.
- Pleasantville: Big Bob, the mayor of the titular fiction-turned-real town, who is bent of keeping everyone in it in the not-so-idyllic '50s forever.
- Point Blank (1967): Yost/Fairfax, Brewster, and Frederick Carter, the trio leading the Organization that's hunting Walker down.
- Point Break (1991): Bodhi, an adrenaline junkie who leads the Ex-Presidents in their bank robbing spree.
- Police Story: Chu Tao, the drug kingpin whom Chan and the rest of the police spend the entire movie trying to take down.
- Poltergeist II: The Other Side: Reverend Henry Kane, a spectral cult leader seeking to return to the human world.
- Poor Albert & Little Annie: Albert Robertson, a violent misogynist obsessed with the 11-year-old Annie.
- Pootie Tang: Dick Leckter, the head of Corporate America who seeks to use Pootie's image to promote tobacco, fast food and malt liquor.
- Popcorn: Toby D'Amato, a disfigured psycho killing people in a movie theatre.
- Porky's: Porky, the owner of the titular strip club who the main characters want to exact revenge upon for kicking them out of the club, as well humiliating and robbing them.
- Predator:
- Predator: The Jungle Hunter Predator, an alien stalking a military unit.
- Predator 2: The Predator known as City Hunter, who has come to Los Angeles with its tribe to hunt humans.
- Predators: Berserker, the leader of the Super Predators hunting humans on the Gaming Planet.
- The Predator: The Ultimate Predator, who's sent by his superiors to dispatch the rogue Predator and recover the Predator-Killer suit.
- President's Day: Leonard Wright, a Serial Killer dressed as Abraham Lincoln.
- Pride and Prejudice and Zombies: George Wickham, the leader of the zombies plaguing England.
- Prime Cut: Mary Ann, the unhinged slaughterhouse owner who Delvin goes out to save Poppy from.
- Prince of Darkness has Satan, who seeks to release his father the Anti-God from his prison and bring about the Apocalypse.
- The Princess (2022): Julius plans to marry the Princess and later Violet in a forced marriage so he can seize the throne for himself.
- The Princess Bride: Prince Humperdinck, who intends to force Princess Buttercup to marry him so he can kill her for the kingdom.
- The Prisoner of Zenda: Duke Michael, who aims to assume the throne of Zenda from Rudolf V.
- Prisoners of the Lost Universe: Klael, an Evil Overlord forcing a scientist from our world to harvest powerful minerals.
- Prisoners of the Ghostland:The Governor, a brutal dictator who forces Hero to bring him back his escaped "granddaughter", lest the suit he forced onto him self-destructs.
- The Private Life of Sherlock Holmes: Gabrielle Valladon, a German spy sent to steal a pre-World War I submarine.
- Pro Wrestlers vs. Zombies: Angus, a Knight Templar Big Brother willing to set zombie hordes on innocents to avenge his brother's death.
- The Professional: Detective Norman Stansfield, the corrupt DEA agent who murders Mathilda's family, leading her to join Léon in order to get revenge on him
- Prom Night
- Prom Night (1980): Alex Hammond, who's killing a group of high schoolers who killed a little girl years ago.
- Hello Mary-Lou: Prom Night II: Mary Lou Maloney, a Vengeful Ghost who possesses one of the main characters and goes on a killing spree to reclaim her title of Prom Queen.
- Prom Night III: The Last Kiss: Mary Lou Maloney again.
- Prom Night IV: Deliver Us From Evil: Father Jonas who targets those he perceives as dirty and tainted.
- Prom Night (2008): Richard Fenton, who breaks out of prison to take one of his students for himself... after he's murdered all her friends so all she'll have left is him.
- The Prophecy: Archangel Gabriel, who seeks Colonel Hawthorne's soul in order to turn the tide of the Heavenly War in his favor.
- The Prophecy II: Gabriel again. This time, aiming to prevent the birth of a Nephilim who's prophesized to bring an end to the Heavenly War.
- The Prophecy 3: The Ascent: Pyriel, the self-appointed Angel of Genocide who's bent on eradicating humanity.
- The Proposition: Arthur Burns, the feared leader of the Burns gang and Charlie's older brother, who he must kill in order to save the life of his brother..
- The Prowler: Sheriff George Fraser, who kills to work out his frustration at receiving a Dear John letter.
- Psycho: Norman Bates' "Mother" personality, who will kill whoever she has to to keep her son under her thumb.
- Pulp Fiction: Marsellus Wallace, the crime boss who controls the city.
- Pumpkinhead: Pumpkinhead, a demon who takes revenge much too far.
- The Punisher (1989): Lady Tanaka, a Yakuza boss who has kidnapped all of her rivals' children to drive them out of the territory.
- The Punisher (2004): Howard Saint, the crime boss who killed Frank Castle's family.
- Punisher: War Zone: Jigsaw.
- Puppet Master: Neil Gallagher, who faked his death and is now killing his friends for immortality.
- The Purge Universe has the New Founding Fathers, who are responsible for creating and maintaining the purge.
- The Purge: A Big Bad Ensemble of Polite Leader, who leads the invasion of the Sardin household in order to kill the homeless man they're sheltering, Henry, who aims to kill James so he can be with Zoey without opposition, and Grace Ferrin, who also wants to kill the family out of envy.
- The Purge: Anarchy: The Old Auction Lady, who seems to be at the top of the hierarchy of gangs paid to deliver people to underground auction club for rich bidders, and Big Daddy, the leader of a death squad/mercenary group sanctioned by the NFFA.
- The Purge: Election Year: A Big Bad Ensemble of Minister Edwidge Owens, the NFFA candidate for the election, and Caleb Warrens, the leader of the NFFA.
- The First Purge: The NFFA, in this case represented by Chief of Staff Arlo Sabian, start the Purge and thus the films' conflict.
- The Forever Purge: Elijah Hardin/Alpha, leader of the Ever After Purgers who want to continue to Purge long after the holiday ends.
Q
- The Queen of Black Magic: Gendon, the Evil Sorcerer who manipulates Murni into taking up sorcery.
- Quigley Down Under: Elliot Marston, an Australian Cattle Baron who wants the local aborigine population slaughtered.
R
- Ragtime: A Big Bad Ensemble of Coalhouse Walker Jr., Fire Chief Willie Conklin, and Harry Kendall Thaw.
- The Raid: Tama, the drug lord that controls the criminal-laden apartment that the strike team raid.
- The Raid 2: Berandal: Bejo, who initiates the gang war, turns Uco against his father, and it's his minions that make up the main threats to Rama.
- Raising Arizona has Leonard Smalls, the biker searching for Nathan Junior to either ransom him or sell him on the black market.
- Rambo:
- First Blood: Sheriff Will Teasle, who harasses John Rambo for no good reason.
- Rambo: First Blood Part II: Lieutenant Colonel Podovsky, commander of the P.O.W. camps in Vietnam that Rambo has been tasked to investigate.
- Rambo III: Colonel Alexei Zaysen, overseer of the Soviet soldiers who kidnapped Colonel Trautman, who Rambo has to rescue.
- Rambo IV: Major Pa Tee Tint, an officer in the Burmese military who captures some missionaries helping a village, and Rambo has to save the missionaries and put a stop to Tint's atrocities.
- Rambo: Last Blood: Hugo Martinez, the leader of the gang who kidnapped the granddaughter of Rambo's friend in Mexico with the intent to sell her into sexual slavery.
- Ran: Lady Kaede, who masterminds a civil war within the Ichimonji clan to avenge her family.
- Ravenous (1999): Colonel Ives, a cannibalistic soldier who kills his way through the cast of the film.
- Rawhead Rex: Rawhead Rex, an ancient monster terrorizing an Irish village.
- Ready Player One (2018): Nolan Sorrento, who wants to win the game in order to turn the OASIS into a monetized pay-to-play advert-filled standard MMO to grossly increase IOI's profits and deprive most of the poor of their access to it.
- Real Steel: Farra Lemkova, a powerful businesswoman who aids Zeus' creator, Tak Mashido.
- Re-Animator and Bride of Re-Animator: Dr. Carl Hill, who plagiarized Herbert West's mentor and becomes a mad zombie out to destroy him.
- Beyond Re-Animator: Warden Brando, a scumbag tormenting people in a prison he runs.
- Red series:
- Red (2010): Alexander Dunning, an arms dealer who uses his CIA connections to cover the Vice President's crimes.
- Red 2: Dr. Edward Bailey, who intends on detonating the Nightshade bomb.
- Red Eye: Jackson Rippner, a Psycho for Hire who forces Lisa to aid him in assassinating the Secretary of Homeland Security.
- Red Heat: Viktor Rostavili, a Georgian crime lord that Danko and Ridzik are tasked with returning to Russia.
- Red River: Tom Dunson, an irrational, tyranical man who controls the cattle industry who wants revenge on his subordinates for turning on him.
- Red Scorpion: General Vortek, a Soviet war criminal who's out to crush the resistance in Mombaka. The sequel has Andrew Kendrick, a neo-Nazi white supremacist determined to take over the United States.
- Red Sun: Gauche Kink, who stole a katana gifted to a US ambassador and betrayed his partner Link Stuart, prompting Link and a Samurai to hunt him down.
- The Reef: The shark picking off the stranded tourists.
- Reefer Madness: The unnamed drug boss selling everybody highly dangerous marijuana.
- Repo! The Genetic Opera: Rotti Largo, a Corrupt Corporate Executive who managed to get the government to agree to let him repossess transplanted organs.
- In Resident Evil Film Series, the Umbrella Corporation is the source of everything bad that happens, with each movie having an individual main antagonist working for Umbrella:
- Resident Evil (2002): The Red Queen, an evil program responsible for sealing the Hive and murdering its workers in order to prevent the virus outbreak.
- Resident Evil: Apocalypse: Major Cain, responsible for the sealed off Raccoon City and the activation of the "Nemesis Project", used to kill off the members of S.T.A.R.S.
- Resident Evil: Extinction: Dr. Issacs, who's out to obtain Alice's blood in order to concoct a new strain of the T-Virus. The Final Chapter reveals him to be a clone, however.
- Resident Evil: Afterlife: Albert Wesker, the chairman of Umbrella who lures the surivors into Arcadia to be experimented on.
- Resident Evil: Retribution: The Red Queen again, having seized control from Wesker. This time, taking over one of Umbrella's testing facilities to amass an army of zombies, bioweapons and mind-controlled Umbrella clones with the intent of wiping out what is left of humanity.
- Resident Evil: The Final Chapter: The real Dr. Issacs, revealed to have been The Man Behind the Man to all of the above.
- Resolution: The unnamed entity, who destroys lives to make interesting stories.
- Reservoir Dogs: Joe Cabot, the crime boss who hires a group of thieves for a jewelry heist.
- The Revenant: A Big Bad Ensemble between John Fitzgerald, who left Glass for dead and killed his son in order to save his own skin; leading him to go on a Roaring Rampage of Revenge, Elk Dog, who hunts down Glass under the belief that he's the trapper who kidnapped his daughter, and Toussaint, the man who actually kidnapped Elk Dog's daughter.
- Revenge of the Nerds: Coach Harris, being the one who instructed the Alpha Betas to commandeer the Nerds' house antagonize at each and every turn; with Stan Gable as The Heavy.
- Revolution (1985): Sergeant Major Peasy, who kidnaps Tom's son to act as a drummer boy for the British army.
- The Ring: Sadako Yamamura, known as Samara Morgan in the US remake versions, a Stringy-Haired Ghost Girl who stalks and kills anybody who watches the tape her spirit is bound to.
- Rio Bravo: Nathan Burdette, a land baron attempting to free his homocidal brother Joe from custody.
- R.I.P.D.: Bobby Hayes, Nick's partner who killed him and is secretly a dead-o plotting to unleash the dead upon the Earth.
- The Ripper: Jack the Ripper, who has returned in the modern day via a magic ring.
- The Ritual: Moder, the creature the murder cult worships.
- The River Wild: Wade, a criminal and murderer who hijacks Hartman family's whitewater rafting trip.
- Road House (1989): Brad Wesley, the leader of the racket that's terrorizing the town.
- Road to Perdition: A Big Bad Ensemble of the crime boss John Ronney, his son Connor Rooney, and Harlan Maguire, a hitman for the Greater-Scope Villain Frank Nitti. John Rooney approves a hit on his surragate son, Michael Sullivan when the latter plans to kill his biological son, Connor. Connor steals money from his father and attempts to cover it up by murdering Michael's wife and son, triggering Sullivan's Roaring Rampage of Revenge. Connor is anticlimactically killed by Sullivan after the latter kills his father, resulting in Nitti and his men withrdawing their protection of Connor from Sullivan's wrath. Lastly, Maguire is hired by Nitti kill Sullivan on Rooney's behalf, but was also secretly tasked with killing Michael Jr. despite Rooney's objection. After the Rooneys are killed and Nitti cancels the hit on Sullivan, Maguire becomes the final antagonist of the film, who hunts down and kills Sullivan, but is killed in turn by Sullivan.
- Rob Roy: James Graham, Marquess of Montrose, who has Rob declared an outlaw after Rob is unable to pay his debt to Montrose and refuses to falsely incrimiate the Duke of Argyll. Montrose's henchman, Archibald Cunningham, is The Heavy who prevents Rob from paying off Montrose in the first place by robbing him, rapes Rob's wife, hunts down Rob on Montrose's orders, and fights Rob in a Duel to the Death on Montrose's behalf during the climax of the film.
- The Robert Langdon saga:
- The Da Vinci Code: Sir Leigh Teabing, who frames Robert for the murder of the Priory members and manipulates him into helping him find the Holy Grail and expose the church's lies.
- Angels & Demons: Camerlengo Patrick McKenna, who plans to become Pope to renew the world's faith in Catholicism and discredit the works of science via having various other religious figures murdered, then staging his own heroic moment.
- Inferno: Sienna Brooks, who drives the plot by orchestrating Robert's amnesia and manipulates him in order to unleash the Inferno virus and wipe out half of humanity.
- RoboCop: Omni Consumer Products (OCP) itself is ultimately the driving force of all of the conflict in RoboCop, being responsible for all of the corruption in Detroit.
- RoboCop (1987): A Big Bad Duumvirate between Clarence Boddlicker, the crime boss of Old Detroit whose actions lead to Murphy becoming RoboCop, and Dick Jones, the vice-president of OCP who actively supplies Boddlicker with his equipment and money.
- RoboCop 2: Cain, the distributor of "Nuke" who's made into RoboCop 2 by OCP and goes on a rampage.
- RoboCop 3: A Big Bad Duumvirate between Paul McDaggett, the commander of the Rehabs, who are hired to kill the poor residents of Detroit, and the new OCP CEO, who the Rehabs answer to.
- RoboCop (2014): Raymond Sellers, the chief officer of OmniCorp, who wants to kill Murphy as a means of pushing his droid enforcement program.
- Robot Monster: The Great Guidance, the space overlord who sent Ro-Man to Earth in the first place.
- The Rock: General Francis X. Hummel, until he is usurped by Captain Fyre and Captain Darrow.
- The Rocketeer: Neville Sinclair, a movie star-turned-Nazi spy seeking a superweapon.
- Rocky:
- Rocky: Apollo Creed, although apart from being Rocky's ultimate opponent he isn't all that evil. The worst he does is trash talk and use Rocky for a publicity stunt.
- Rocky II: Apollo Creed, whose scant victory in the previous film leads him to challenge Rocky again in order to solidify his title as champion, with the two eventually developing a mutual Worthy Opponent relationship.
- Rocky III: Clubber Lang, who dethrones Rocky as the champion at the start of the film, leading him to spend the rest of the movie training in order to take it back.
- Rocky IV: Ivan Drago, who makes things all the more personal by beating Apollo to death in what was supposed to be an exhibition match, which leads to Rocky challenging him.
- Rocky V: Tommy Gunn, who starts off a young prodigy of Rocky before betraying him for George Washington Duke. While Duke is also a proactive villain throughout the film, he ends up not being able to hold Tommy on a leash, leading Tommy to become the main threat at the end.
- Roh: Tok, the kindly old woman helping the family in their struggle against the supernatural evil plaguing them, who turns out to be a demon responsible for said evil, which is mostly illusionary rather than physical and meant to make humans turn against and destroy each other.
- Rolli – Amazing Tales: The High Priest of the Trashers plans to diabolically destroy the Rölli Forest by polluting it into lifelessness. He's technically The Dragon of the Great Trash, the Trashers' deity, but he has a lot more screen-time, and he's the one who gives the Trashers all the orders and devices their plans. After the Great Trash has died and the Trashers dispersed, the High Priest tries to kill the heroes, threatening afterwards to convert new Trashers and destroy the forest. It's after his death that the threat is considered to be finally over.
- Rolling Thunder: The Texan, the gang leader who killed Charles Rane's family.
- Rolling Vengeance: Tiny Doyle, a Small-Town Tyrant who gives his sons free reign to terrorize his small town.
- Rollo and the Spirit of the Woods: Lackey, the glib adviser of the rolley tribe's chieftain, is ultimately the most mean-spirited of all the rolleys. After the old chieftain leads the tribe to settle in the village of elves and passes away, Lackey is the most vocal about the tribe's refusal to live peacefully with the elves. After Big Rolley becomes the chieftain by force, Lackey proceeds to influence the tribe through him, and then through Rolli when the latter replaces Big Rolley, manipulating him to attack the elves, which leads to Millie's Disney Death and the sun being concealed by the moon. He's ultimately stripped of all authority, allowing the rolleys and elves to coexist peacefully.
- The Room (2003): Lisa, Johnny's adulterous girlfriend whose seduction of his best friend causes the plot.
- Runaway: Dr. Charles Luther is responsible for the robot rampages.
- The Running Man: Damon Killian, the host of the titular show that Ren Richards is forced to participate in.
- Rush Hour:
- Rush Hour: Juntao/Thomas Griffin, who kidnaps Han's daughter as payback for his criminal empire being squandered.
- Rush Hour 2: Ricky Tan, a Triad leader who orchestrates a bombing on China's U.S. Embassy as a means of distracting from taking his counterfeiting racket to a Las Vegas casino.
- Rush Hour 3: Kenji, Lee's estranged foster-brother and a criminal mastermind out to kill Genevieve, a woman under Lee and Carter's protection, for her information on the Triad.
- The Rocky Horror Picture Show: Dr. Frank-N-Furter, a mad scientist who runs a castle of debauchery.
- Shock Treatment: Farley Flavors, the owner of DTV who intends on molding Janet into the network's next big star.
- Robin Hood: Prince of Thieves: Sheriff George of Nottingham, who intends to take over Locksley by force.
- Robot Holocaust: The Dark One, an alien who caused the near-extinction of humanity and rules over its remains.
- Rosemary's Baby: Minnie and Roman Castevet, the heads of a satanic cult who intend to use Rosemary to spawn The Antichrist; with Satan as the Greater-Scope Villain.
S
- Sahara (2005): Brigadier General Zateb Kazim, Mali's oppressive ruler who's responsible for the nation's water supply getting polluted.
- The Saint (1997): Ivan Tretiak, a billionaire who dominates the gas and oil market in Moscow and is responsible for its freezing crisis.
- Salt: Ted Winter and Oleg Vasilyevich Orlov, both of whom kidnap Evelyn Salt's husband and forces her to assassinate the Russian and US Presidents with the intention of kickstarting a nuclear war.
- Salvador: Major Maximiliano Casanova, the leader of the far-right ARANA party and the head of death squads plaguing El Salvador
- Samson and Delilah (1949): The Saran of Gaza, the emperor of the Philistines oppressing the Hebrews.
- Samurai Cop: Fujiyama, a Yakuza boss out to take over Los Angeles' drug trade.
- Satan's Slave: Darminah, a demon who torments and enslaves lapsed Muslims.
- Satan's Little Helper: The Satan Man, a Serial Killer pretending to be Satan.
- Savaged: Trey, leader of a gang of rednecks who kill Native Americans for fun.
- Savages: Elena Sánchez, the leader of a Mexican drug cartel who intends on expanding their operations in the US by taking over Ben and Chon's weed business.
- Saw: Jigsaw, whether it be John Kramer or Mark Hoffman, is the mastermind of all the murderous "games" that the series' victims are forced into.
- Spiral (2021): The Jigsaw copycat, aka William Schenk, who is using the same techniques to kill Dirty Cops.
- Sawney: Flesh of Man: Mother Bean, a ravenous loon whose children commit cannibalism just to sate her.
- Scalps: Black Claw, the ghost of a Native American warrior who goes on a gruesome killing spree.
- Scanners: Darryl Revok, the leader of the scanner underground movement plotting to take over society.
- Scarface (1932): Tony Camonte, a gangster who spends the film climbing his way to the top of the Chicago underworld. He serves part of the film as Johnny Lovo's Dragon-in-Chief, during which time he defies Johnny's orders by waging a gang war under the control of O'Hara, and afterwards, Tom Gaffney, successfully wiping them out. Eventually, Tony has Johnny killed and becomes the boss of his gang outright.
- Scarface (1983): Alejandro Sosa, a cartel boss who is on the top of the crime heap we see and ends up becoming the primary opposition to Tony Montana's rise to power.
- Scarecrow (2002): Chad causes all the bloodshed in the film by being Lester's primary tormentor.
- Scary Movie: Doofy Gillmore, who fakes intellectual disability to hide his Serial Killer nature.
- Scary Movie 2: Hugh Kane, a ghost who terrorizes the visitors of Hell House.
- Scary Movie 3: Tabitha, who seeks to kill anyone who sees a cursed tape.
- Scary Movie 4: The Saw Villain, who leads an alien invasion of the Earth.
- Scary Movie 5: Mama, who seeks to sacrifice the children of Charlie Sanders.
- Schindler's List: Amon Goeth, commander of the local concentration camp.
- Scott Pilgrim vs. The World: Gideon Gordon Graves, the leader of the League of Evil Exes who Scott must overcome in order to date Ramona.
- Scream has the various incarnations of the Ghostface Killer:
- Scream (1996): Billy Loomis and Stu Macher.
- Scream 2: Mrs. Loomis and Mickey Altieri.
- Scream 3: Roman Bridger, who doesn't have an accomplice.
- Scream 4: Jill Roberts and Charlie Walker.
- Scream (2022): Richie Kirsch and Amber Freeman.
- Scream VI: Detective Bailey and his children Quinn and Ethan.
- The Screaming Skull: Eric Whitlock, who's trying to drive his wife to suicide for the money.
- Seizure has the Queen of Evil.
- The Searchers: Chief Scar, a Comanche chief who was responsible for the murder of Ethan Edwards' family with the exception of his niece Debbie, who Scar kidnapped and claimed as a wife.
- A Serbian Film: Vukmir Vukmir, the man in charge of the horrific Snuff Film operation.
- The Sea Hawk: King Phillip II, with Lord Wolfingham as The Heavy.
- Serenity: The Operative, a special agent of the Alliance Parliament assigned with killing River Tam, who is under the protection of the Serenity crew.
- Serial Mom: Beverly Sutphin, a housewife who goes about murdering anyone who personally offends her values.
- The Serpent and the Rainbow: Captain Dargent Petraud, a sadistic voodoo sorcerer who runs Haiti's Secret Police to get souls to enslave.
- Se7en: John Doe a Serial Killer murdering people based on the Seven Deadly Sins who Somerset and Mills are trying to bring in.
- Seven Samurai: The unnamed bandit leader who spearheads the village raid.
- The Seventh Curse: Old Ancestor, the Human Sacrifice demanding demon god of the Worm Tribe.
- The Seventh Seal: Death, who Antonius Block must defeat in chess in order to keep his life.
- The Shadow: Shiwan Khan, the descendant of Genghis Khan who plans to destroy New York City in order to get the rest of the world to kneel before him.
- Shadow of the Vampire: Max Schreck, a vampire who joins Murnau's film and attempts to feed on the entire crew.
- Shane: Rufus Ryker, who tries to drive the homesteaders off their land for his own benefit.
- Shaft: Lee, a thug who's kidnapped a Harlem mobster's daughter for The Mafia.
- Shapeshifter: Marcoux, a Russian mobster whose imprisonment started the Shapeshifter's rampage.
- Sharktopus: The Sharktopus, a an out of control U.S. Navy experiment that goes on a rampage.
- The Shawshank Redemption: Samuel Norton, the corrupt warden of Shawshank.
- SheChotic: Maxine's murderous alter ego who wants revenge on her boyfriend for cheating on her and will gladly tear down anyone who stands in her way.
- She Wore a Yellow Ribbon: Chief Red Shirt, who wants to kickstart a new frontier war.
- Sherlock Holmes (2009): Lord Henry Blackwood, who intends on using his Temple of the Four Orders organization to conquer Britain, and eventually, the world.
- Sherlock Holmes: A Game of Shadows: Professor James Moriarty, who intends on kickstarting World War I, with the intent of profiting off of it through his shell companies.
- A Shock to the System: Graham Marshall, who decides on murdering his wife and boss for how they've wronged him.
- Sholay: Gabbar Singh, the bandit leader who terrorizes Ramgarh.
- The Shootist: Mike Sweeney, Jack Pulford, and Jim Cobb; all of whom want Books dead for different reasons.
- Shotgun (1989): Fletcher Rivington, an Amoral Attorney who tortures women as a hobby in-between his attempts to take over Los Angeles.
- Showdown in Little Tokyo: Funekei Yoshida, a Yakuza boss who controls the Los Angeles drug trade.
- Sicario: Fausto Alarcón, the head of the Sonora Cartel and Alejandro's main target.
- Signs has the Aliens who invade Earth and capture humans.
- Silence: Inquisitor Inoue, a ruthless daimyo charged with rooting out Christian influence in Japan.
- Silent Night, Deadly Night: Billy Chapman, a lunatic killing "naughty" people in a Santa costume.
- Silent Hill: Christabella, the religious fanatic whose ceremonies cursed the town.
- Silver Lode: Fred McCarty, the leader of the group of men riding into Silver Lode looking for Dan Ballard, is the main antagonist and directly or indirectly responsible for all the bad things that happen in the movie.
- Sin City:
- The Hard Goodbye: Kevin, a Seiral Killer and cannibal who murders Goldie, the love of Marv's life, and Cardinal Patrick Henry Roark, who actively protects Kevin and allows him to continue his cannbalistic activities in his barn.
- The Big Fat Kill: Manute, who seeks to destroy Old Town when the prostitutes there killed one of his organization's Dirty Cops.
- That Yellow Bastard: Ethan Roark Jr., whose attempts to rape Nancy force Hartigan to come after Junior to defend her.
- Sin City: A Dame to Kill For:
- A Dame To Kill For: Ava Lord, who tries to manipulate into murdering her husband.
- The Long Bad Night: Senator Roark, who wants to make Johnny suffer for humiliating him in a game of poker.
- Nancy's Last Dance: Senator Roark again, who Nancy wants revenge against for driving Hartigan kill himself.
- Sinister: Bughuul/Mr. Boogie, a ancient pagan god who corrupts children into killing their families; with the Oswalt family being his latest target .
- Sisters (1973): Danielle Benton, who formed a homicidal persona when her conjoined twin sister died in the separation process.
- Sisu: Bruno Hellendorf, an SS Obersturmführer who leads a Wehrmacht platoon trying to steal Aatami's gold.
- Skin Trade: Viktor Dragovic, head of a Russian Mob Human Trafficking operation.
- Slash (2002): Jethro MacDonald, a scarecrow-clad madman killing people for blood sacrifices.
- The Slaughter: The Lady of Darkness, a demoness plotting to destroy the world.
- Sledgehammer (1983): The unnamed ghost killing everybody.
- Sleepaway Camp: Angela/Peter, the Camp Arawak killer.
- Sleeping with the Enemy: Martin Burney, Laura's abusive husband whom she tries to escape from.
- Sleepy Hollow (1999) has Lady Mary Van Tassel. It's her lust for revenge that drives the Horseman to kill for her.
- The Slumber Party Massacre trilogy:
- The Slumber Party Massacre: Russ Thorn, a mass murderer who escaped from a mental hospital to continue killing people.
- Slumber Party Massacre II: The Driller Killer, a supernatural Rockabilly who wants to make the main character his.
- Slumber Party Massacre III: Ken, who has been inspired by the death of his perverted uncle to kill people.
- Smiley: Proxy, Binder, Zane, and Mark, who all masquerade as Smiley to torment Ashley to the point of being Driven to Suicide.
- Smokey and the Bandit: Sheriff Buford T. Justice, who's out to capture Smokey for making off with his son's bride-to-be.
- Snake Eyes: Commander Kevin Dunne, who masterminded the plot to assassinate the Secretary of Defense.
- Snakes on a Plane: Eddie Kim, a sadistic mob boss who sets snakes onto a plane to eliminate a witness.
- Snowpiercer: Wilford. He created the Snowpiercer train, and is responsible for the caste system that keeps the tail-enders in such nightmarish exploitative conditions. He also uses Gilliam to causes rebellions that are intended to fail as a means of population control, with Curtis's being only the most recent.
- Society: Judge Carter, master of a Body Horror cult of rich people.
- Sodom and Gomorrah: Queen Bera of Sodom is the embodiment of all vice in this version of the Old Testament story. She kidnaps innocent people to use as slave labour in the salt mines that have made her cities wealthy, tortures them to death for information or simply for entertainment, actively encourages the depravities of every free citizen under her rule, and takes personal satisfaction in corrupting the devout Lot and the other Hebrews with the life of decadence available within Sodom's walls. Such is Jehovah's displeasure with her and everything she represents that He razes the cities to the ground.
- A Soldier's Story: Private Peterson.
- Solo (1996): General Clyde Haynes, the military official who ordered Solo created and now wants him destroyed.
- Some Like It Hot: Spats Colombo. He'ss the Chicago mafia boss responsible for gunning down a rival gang and hunting down Joe and Jerry as witnesses, forcing them to go undercover as women. At least until he's killed by his boss, Little Bonaparte, who takes over as main villain for the last part of the film.
- Someone to Watch Over Me: Joey Venza, who attempts to kill socialite Claire Gregory, the sole witness of his murder of Winn Hockings; with Detective Mike Keegan being assigned with protecting her.
- Something Wild: Ray Sinclair, a low level thief that robs convenience stores and an abusive, would-be rapist.
- The Sons of Katie Elder: Morgan Hastings, who murdered Katie Elder to get her farm.
- The Sound of Music: Herr Zeller, a Nazi Gauleiter attempting to force Captain Georg von Trapp into the Kriegsmarine.
- South Bronx Heroes: Mr. Bennett, a foster parent who makes child porn of his charges.
- Space Mutiny: Elijah Kalgan, the mastermind of a conspiracy to overthrow a Generation Ship and sell the other inhabitants into slavery.
- Spaceballs: President Skroob, who plans to steal the air from the planet Druidia to relocate it to his own planet, Spaceball. However, his henchman, Dark Helmet takes a more active role in the plot by hunting down Princess Vespa and using her to blackmail her father into giving up the combination to the shield protecting Druidia from harm. Dark Helmut is also the final obstacle preventing Lone Starr from activating the Self-Destruct Mechanism for the Mega Maid, the device being used to suck the air from Druidia.
- Spawn (1997): Malebolgia, who revives Al Simmons with the intent of making him the leader of his army and start Armageddon. His minion Clown/The Violator, takes a more active role in enforcing Simmon's end of the bargain. Additionally, Jason Wynn, the corrupt CIA Director who murders Simmons, attempts to use a virus, which can be triggered by a Dead Man's Switch in the event of Wynn's death, to hold the world hostage, only to play into the hands of Malebolgia and Clown, who intend to have Simmons kill Wynn to fulfil the aformentioned plan to start Armegeddon.
- Speed: Howard Payne, a Mad Bomber who rigs a bus full of people to explode if it goes under 50 mph, unless he's paid a ransom.
- Speed 2: Cruise Control: John Geiger, who hijacks the cruise ship Annie and Alex are on and puts it on course to collide with an oil tanker.
- Spotlight: Cardinal Bernard Law, mastermind of a mass coverup of sexual abuse in the Boston Catholic Church.
- SS Doomtrooper: Dr. Ullman, a Mad Scientist making Nazi super soldiers.
- Stagecoach: Geronimo, the leader of the Apaches who is responsible for much of the danger the party faces, and the Plummer Brothers, the gang of killers and archenemies of the Ringo Kid.
- Stage Fright (2014): Roger McCall, the seemingly-kind head of a theatre camp, who secretly started the plot by killing the killer's mother.
- Stalag 17: Price, The Mole sabotaging the prisoners' clandestine resistance efforts and escape attempts, and using Sefton as a scapegoat.
- Starship Troopers: The Brain Bug, the leader of the Bugs at war with humanity.
- Starship Troopers 3: Marauder: It's revealed that the Brain Bugs are actually in thrall to an even higher leadership caste of which there is only one member, the humongous Bug God Behemecoatyl.
- Stardust: Lamia, an evil witch that desires Yvaine's heart so she may remain young and beautiful.
- Stargate: Ra, an Ancient Astronaut using his advanced knowledge to enslave two planets, putting on a God Guise and ruling his subjects with an iron fist.
- Stargate: The Ark of Truth: Adria, who has become the leader of the Ori after the previously ascended all died.
- Stargate: Continuum: Ba'al, who goes back in time to destroy Earth's Stargate, leaving the planet for a Goa'uld invasion until he's usurped by Qetesh.
- State of Play: Stephen Collins, the one responsible for the death of Sonia Baker.
- The Stepfather and the 2009 remake: The unnamed stepfather, who keeps marrying into families and killing them when they fail to meet expectations.
- Stitches (2001): Mrs. Albright, a demoness manipulating people into giving her their souls.
- Stitches (2012): Stitches the Clown, a Vengeful Ghost after the teens who accidentally killed him as children.
- Stone Cold: Chains Cooper, a neo-Nazi biker plotting to assassinate a politician.
- The Strange Thing About the Johnsons: Isaiah Johnson, a young man who's raping his own father.
- The Stranger: Franz Kindler, a notorious Nazi war criminal hiding in the U.S. who Mr. Wilson is hunting down.
- Stray Cat Rock: Delinquent Girl Boss: Mr. Hanada, a gangster who declares war on the Stray Cats.
- Street Fighter: M. Bison, a military dictator with grand designs to unite the world under his own unhinged machinations.
- Streets of Fire: Raven Shaddock, a biker gang leader who abducts a pop star.
- Strike Commando: Colonel Radek, Ransom's CO who is also behind the Russian officers in Vietnam.
- Sucker Punch: Blue Jones, the corrupt head of the Lennox House asylum.
- The Suckling: Phil, an abusive boyfriend who makes his girlfriend get the abortion that mutates into the titular monster.
- Sudden Death: Joshua Foss, who holds the Pittsburgh Civic Arena hostage during the Stanley Cup Finals.
- Summer of '84: Officer Wayne Mackey, the true identity of the Cape May Slayer who's now targeting Davey.
- Sunrise: The Woman From the City, who is responsible for making the man nearly drowning his wife.
- Sunshine: Pinbacker, who works to sabotage the attempts of the Icarus II crew to reignite the Sun.
- Super Fly: Deputy Commissioner Reardon, the Dirty Cop who controls Harlem's drug trade.
- Each of the Super Hero Taisen films has a Big Bad.
- Kamen Rider × Super Sentai: Super Hero Taisen starts off with a Big Bad Ensemble between Tsukasa Kadoya and Emperor Marvelous, each commanding a Legion of Doom comprised of various past villains. It's later revealed that the true Big Bad is a Big Bad Duumvirate of Narutaki/the fake Doktor G and Rider Hunter Silva, who were manipulating the two into killing off the Kamen Riders and Super Sentai so they could Take Over the World with the Big Machine.
- Kamen Rider × Super Sentai × Space Sheriff: Super Hero Taisen Z has Demon King Psycho, with the Big Bad Duumvirate between Shadow Moon and Reider serving as The Heavy and the ones working to revive him.
- Heisei Rider vs. Showa Rider: Kamen Rider Taisen feat. Super Sentai has the Generalissimo of Badan, ruler of the Badan Empire and the one behind the plot to raise Badan's underworld Legion of Doom into the world of the living.
- Super Hero Taisen GP: Kamen Rider #3 has the Great Leader of Shocker, whose spirit once again rules Shocker in the Bad Future where they conquered the world.
- Kamen Rider × Super Sentai: Chou Super Hero Taisen has a Big Bad Duumvirate of Eight Kirino and Game World Hiiro Kagami as the masterminds behind the attacks from the Game World, with Shocker (led by Shocker Leader III) serving as the climax boss.
- Supersonic Man: Dr. Gulik, a Mad Scientist seeking an all-powerful element.
- Survivor (2015): The Watchmaker, who intends on setting off a bomb in Time Square.
- Suspiria (1977): Helena Markos, AKA Mater Suspiriorum, a Wicked Witch who dominates a ballet school.
- Sweeney Todd: The Demon Barber of Fleet Street has Judge Turpin, a corrupt judge who sent Benjamin Barkerto Botany Bay under false charges so he can rape his wife; driving Benjamin to become the killer Sweeney Todd.
- Sweet Smell of Success: J.J. Hunsecker, who attempts to break apart Susan and Steve by framing the later for being a communist.
T
- Taken:
- First film: Marko Hoxha, the leader of the kidnappers, and Patrice St. Clair, the man who auctions off the kidnapped girls. Sheik Raman's bodyguard serves as the Final Boss, while Sheik Raman himself, as the man who ultimately purchased Kim, is the last obstacle faced.
- Taken 2: Murad Hoxha, Marko's father who is intent on avenging his son.
- Taken 3: Stuart St. John, who had Lenore killed to collect her life insurance to pay off Malenkov.
- The Taking of Pelham One Two Three has Mr. Blue, the mastermind behind the titular hijacking.
- A Tale of Two Cities: Madame Therese Defarge, who seeks the destruction of anyone even remotely related to the Evrémondes after the Evrémonde brothers killed her family.
- A Tale of Two Sisters: The real Heo Eun-ju, who caused Su-mi's mental break by letting Su-yeong die.
- Tales of Halloween:
- "Sweet Tooth": Sweet Tooth, a homicidal candy-obsessed spirit.
- "The Night Billy Raised Hell": Mr. Abaddon, a demon tormenting a child who pranked him.
- "Trick": Caitlyn, leader of a gang of child torturers.
- "The Weak and the Wicked": Alice, a sadistic gang banger tormenting children.
- "Grim Grinning Ghost": Mary Bailey, a ghost stalking a young woman.
- "Ding Dong": Bobbie, a witch plotting to eat a child.
- "This Means War": Boris, a guy going insane over his neighbor's Halloween decorations.
- "Friday the 31st": An unnamed Serial Killer stalking the woods.
- "The Ransom of Rusty Rex": Rusty Rex, a demon who binds himself to poor victims.
- "Bad Seed": Milo, a corporate stooge distributing mutant pumpkins.
- Tank Girl: Kesslee, a Corrupt Corporate Executive who controls all the water in a post-apocalyptic world.
- Taxi Driver has Sport, a pimp that becomes the primary target of Travis after he kidnaps Iris.
- Team America: World Police: Kim Jong-il, who finance various terror organizations around the world in order to launch a simultaneous attack that would reduce every nation of the world to third-world status.
- Tears of the Sun: Col. Idris Sadick, with General Mustafa Yakubu as the Greater-Scope Villain.
- Ted: Donny, who kidnaps Ted with the intention of keeping him as a toy. He's also this in the sequel, this time cutting a deal with a toy company to make more toys like Ted accessible by kidnapping Ted and dissecting him.
- Teenage Mutant Ninja Turtles (1990): The Shredder, the leader of the Foot Clan responsible for the crime wave plaguing New York City.
- Teenage Mutant Ninja Turtles II: The Secret of the Ooze: The Shredder again, who's out to get revenge on the Turtles for his previous defeat.
- Teenage Mutant Ninja Turtles III: Walker, an English Arms Dealer who supplies Noringa's weaponry.
- Teenage Mutant Ninja Turtles (2014): The Shredder. As if there was any doubt. He's the leader of the Foot Clan and aspires to take over New York City with a biological toxin.
- Teenage Mutant Ninja Turtles: Out of the Shadows: Kraang, who's out to destroy Earth and takeover the universe with the Technodrome, with Shredder as The Heavy providing him with the necessary components to send him to Earth.
- Teenagers from Outer Space: The unnamed leader of the aliens, who wish to put their livestock on Earth to devour the humans.
- The Ten Commandments: Rameses II, who actively oppresses the Hebrew people.
- Tenebre: Peter Neal turns out to be a vicious sadist who inspired the initial killer, and ends up committing his own murders after taking him out.
- The Terminal: Frank Dixon, who tries to force Victor to leave the airport.
- Terminator: Skynet serves as the overall main antagonist, but each film has it sending one of its robotic assassins to kill John Connor.
- Terminator: Dark Fate: With Skynet out of the picture, Legion is the new main antagonist of the franchise, sending Rev-9 to kill Dani Ramos.
- Terror Train: Kenny Hampson, an ex-psychiatric patient taking revenge for a hazing prank involving a cadaver.
- TerrorVision: The Hungry Beast, a ravenous alien monster brought to Earth by satellite TV signals.
- Tetris (2023): Robert Maxwell. The film takes many liberties to create a presentable on-screen retelling of events, but Maxwell was every bit the scummy fraudster he is portrayed in the movie. If anything, his own son Kevin Maxwell says the film is a little too charitable with how it portrays him. However, since it would make little sense to have him actively chase down Henk and his partners, he remains a Non-Action Big Bad.
- Tetsuo: The Iron Man: Yatsu the Metal Fetishist, a madman who wishes to turn the world into metal.
- The Texas Chainsaw Massacre: Leatherface is The Heavy of the series, but he is usually taking orders from someone else.
- The Texas Chain Saw Massacre (1974) and its sequel: Drayton "The Cook" Sawyer, the de facto patriarch of the Sawyer clan who continues the cannibalism operation from his grandfather.
- Leatherface: The Texas Chainsaw Massacre III: Edward "Tex" Sawyer, who became the head of the Sawyer clan after the Cook's death.
- Texas Chainsaw Massacre: The Next Generation: Vilmer Slaughter, the head of the Sawyer family who's in on an Illuminati conspiracy to spread fear.
- The Texas Chainsaw Massacre (2003): Sheriff Hoyt, who's in charge of the Hewitt family and poses as a local sheriff in order to help them kill people.
- The Texas Chainsaw Massacre: The Beginning: Luda Mae Hewitt, the matriarch of the Hewitt family responsible for their murderous, cannibalistic lifestyle.
- Texas Chainsaw 3D: Mayor Burt Hartman, who lynched the Sawyer family, and sets out to finish the job by killing Heather.
- Leatherface: Verna Sawyer, the matriarch of the Sawyer clan, with her efforts to get her son back setting off the plot, and facilitating his corruption into Leatherface once and for all.
- Texas Chainsaw Massacre (2022): Leatherface himself is finally the unambiguous main villain, going on a rampage and murdering the influencers responsible for the death of his mother.
- Theatre of Blood: Edward Lionheart, a spurned actor pursuing vengeance on the critics who mocked him.
- Thelma & Louise has Detective Hal Slocumb, Thelma and Louse's primary persuer.
- The Thing (1982) and its 2011 prequel has the titular alien, with its ability to spread like a virus and replicate any living thing it absorbs causing paranoia at the camps as everyone tries to figure out who's human and who's the alien in disguise.
- The Thin Man: Herbert MacCauley, the true identity of the killer.
- Think Fast, Mr. Moto: Joseph B. Wilkie, the head of the smuggling operation.
- The Third Man: Harry Lime, who's been running an underground penicillin racket, leaving countless men, women, and children poisoned.
- Thir13en Ghosts: Cyrus Kriticos, who intends on killing Arthur in order to complete a ritual that will give him infinite power.
- This Means War (2012): Karl Heinrich, a German criminal mastermind intent on getting revenge for his brother's death early in the film.
- Thou Shalt Not Kill... Except: An unnamed cult leader terrorizing a small town.
- Three Flavours Cornetto Trilogy:
- Shaun of the Dead: David, who acts as a constant burden to Shaun's party and attempts to kill him twice for being with the woman he loves.
- Hot Fuzz: Inspector Frank Butterman, the leader of the conspiracy to kill anyone who commits crime, no matter how minor, in a twisted effort to make Standford a perfect village.
- The World's End: The Network, an alien entity who eradicates most of humanity and replaces them with androids.
- The Three Musketeers (1993): Cardinal Richelieu, who plots to take control of France from King Louis XIII.
- The Three Musketeers (2011): A Big Bad Ensemble between Milady de Winter, whose betrayal led to the Musketeers' downfall, and Cardinal Richelieu, who's out to seize control of France.
- Throne of Blood: Asaji Washizu, who manipulates Taketoki into committing various murders.
- Tian Di: Paul Tai, a Villain with Good Publicity who appears to be Shanghai's leading philanthropist, but is actually running an opium trafficking syndicate condemning the city into permanent addiction. And has the police, military and political parties under his payroll. And even gets a The Bad Guy Wins ending.
- Tigers Are Not Afraid: Servando Esparza, AKA El Chino, the brutal drug lord terrorizing the city.
- Time After Time: John Leslie Stevenson, AKA Jack the Ripper, who has stolen a time machine to escape arrest.
- Timecop: Aaron McComb, who abuses time travel in order to become a despot.
- To Die For: Suzanne Stone Maretto.
- Toho's non-Godzilla tokusatsu films have plenty of Big Bads:
- Invisible Man: The villain is not the invisible man Nanjō, who's actually the kindly protagonist. It's Yajima, leader of a gang of criminals, who capitalizes on the the recent revelation of the invisible man's existence to go on a bank-robbing spree with his men posing as invisible men.
- Half Human: Oba starts out as the Big Bad, being the unscrupulous circus animal broker who seeks to capture the elusive snowman of the Japanese Alps and make a mint exhibiting him. When he kills the snowman's son in the process, the snowman goes mad, killing Oba and his henchmen and then terrorizing all humans it comes across, becoming the final threat.
- Legend of the White Serpent: There are two independent antagonists who cause the problems for the heroes. This being an adaptation of the Chinese fairy tale "Legend of the White Snake," one of them is the Taoist monk who seeks to unmask Bai Niang, aka Madame White Snake, as a snake spirit to her beloved husband Xu Xian and kill her. The other is original character Wang Ming, the lecherous moneylender who tries to force Bai Niang into sleeping with him and ultimately sets in motion the events that reveal her.
- The Mysterians: The leader of the Mysterians, a remnant of an alien civilization destroyed by nuclear war. He leads his people in the attempted annexation of a significant chunk of Japan and the kidnapping of human females which whom they can reproduce.
- Throne of Blood: Taketoki Washizu and his wife, Asaji. Asaji is the schemer and most ambitious of the two, being the one who pushes Washizu into betraying and usurping his daimyo, but Washizu is the one who holds the actual power and it is ultimately his choice (or is it?) to go along with his wife's plan. The eerie spirit of the Spider's Web forest might also be considered a Big Bad, as it is her prophecy that sets the whole plot in motion and her goading encourages Washizu to pursue his destiny to its bloody end.
- The H-Man: There are two separate Big Bads. The most dangerous are the H-Men, horrifying sometimes-humanoid blob monsters that were once human until their encounter with H-bomb radiation. They have the nasty ability of transforming those they come into contact with into H-Men as well. The other Big Bad is a more human evil, Uchida, leader of a gang of drug smugglers, who unwittingly becomes entangled in the H-Men's rampage when one of his men becomes an H-Man.
- The Three Treasures: Ōtomo no Takehi, one of Emperor Keikō's scheming advisors, who plots to get the first-in-line to the throne, the legendary Yamato Takeru, killed so that his nephew will succeed the emperor instead.
- Battle in Outer Space: The alien Natal, who seek to subjugate Earth.
- The Secret of the Telegian: The Telegian, who is actually the ex-soldier Sudō, posing as scientist's assitant Goro Nakamoto, using a transmitter machine to teleport himself to his target's location, where he exacts Revenge on the former comrades who left him for dead after he tried to prevent their theft of gold bars at the end of the war. His goals would be sympathetic if he wasn't so embittered by what happened to him that he doesn't care who he has to hurt to get his vengeance.
- The Human Vapor: Mizuno, the test subject of an experiment that had the bizarre side effect of giving him the power to turn into vapor without any loss of bodily cohesion or intelligence, and the gruesome ability to asphyxiate people with said vapor. He's obsessed with Fujichiyo Kasuga, and will do anything to facilitate her comeback dance performance, even bank robbery and murder.
- The Last War: The Federation and the Alliance, expies for the United States and Soviet Union respectively, whose brinkmanship provokes a nuclear war with innocent Japan caught in the middle.
- Matango: The eponymous Matango, which turn people who eat them into mushroom people. While it's questionable whether the original mushrooms are actively malevolent, they may exert some sort of influence to get people to ingest them, and the mushroom people are unquestionably intentional in their efforts to force people to eat Matango.
- The Lost World of Sinbad: The evil Premier, who's secretly poisoning the king, ruining his reputation among the populace, and plotting to marry the princess.
- Atragon: The Empress of Mu, a lost Pacific empire that once ruled the entire world before it sank. After millennia of being forgotten by the surface world, the Empress reignites Mu's imperialistic ambitions and seeks to once again make the other lands her colonies.
- The Adventure of Taklamakan: The Chamberlain, who leads a cabal of treacherous courtiers working to make their paranoid, misanthropic king a despised tyrant whom they will then overthrow with popular support. At the climax of the film, however, the bandit leader Gorjaga, power-hungry and sick of his belittling treatment at the hands of the Chamberlain, kills his boss and attempts to claim the throne himself.
- King Kong Escapes: Dr. Who (no, not that one) and Madame Piranha. The former is an evil scientist who seeks to unearth a huge deposit of the rare and powerful Element X (enslaving King Kong to do so), while the latter is a spy and representative for an unnamed Asian country bankrolling Dr. Who that wants to exploit the resource. Madame Piranha is the more sympathetic of two, genuinely hopeful that the wealth that would come from a monopoly over Element X will improve her country's conditions and increasingly disturbed by the lengths Dr. Who will go to to achieve his goals. This leads to Madame Piranha betraying Dr. Who, and him killing her for it.
- Latitude Zero: Malic, archenemy of Captain Craig McKenzie of the Alpha, and perennial foe of the undersea utopia Latitude Zero. His long-term goal is world domination, but his immediate goals, the ones that drive the conflict, are killing McKenzie and kidnapping and conscripting Dr. Okada, a Japanese scientist who developed a formula granting immunity to radiation.
- The Vampire Doll: Yūko Nonomura, a hate-filled undead woman who murders anyone she comes across. She was resurrected by a supernatural post-hypnotic suggestion implanted by the other Big Bad, Dr. Yamaguchi, a physician obsessed with the occult who was responsible for the mass murder of Yūko's mother's family and household, and her father by rape. Yamaguchi is possessive of Yūko and her mother, though he never intended for his daughter to come back as an undead monster that he has no control over. Yūko's murderous behavior stems from her suppressed rage towards what her mother suffered through, and she ends up killing Yamaguchi when she encounters him.
- Lake of Dracula: The unnamed vampire who, having met and become obsessed with heroine Akiko Kashiwagi when she was a child years ago, seeks to turn her and make her his bride.
- Evil of Dracula: The principal of Seimei Women's Junior College and his wife, both of whom are actually centuries-old vampires who maintain their cover by inviting an unsuspecting teacher (the latest of which is the protagonist Shiraki) to be the former's "successor," which means being killed and having their face literally taken by the principal (his wife would take the face of one of the college's unfortunate students).
- ESPY: Ulrov, the powerful psychic leader of the evil organization Anti-ESPY, who sees psychics as being a separate superior species to humans, and who seeks to instigate a nuclear war between the East and the West that will leave only psychics alive. The heroes muse at the end, however, that Ulrov may have been controlled by an alien intelligence.
- House: Auntie, a ghost woman waiting forever for her dead fiancé to return from the war, luring unwed girls to her Haunted House and eating them to sustain her existence.
- The War in Space: Commander Hell, the leader of the alien attack on Earth. He and his people, having fled their dead world Messiah 13, intend to take Earth as their new home.
- Bye Bye Jupiter: While the main threat is the traveling black hole that is threatening to collide with the Sun, there is a Big Bad in Anita June Pope, leader of a radical faction of the Jupiter Church and insanely devoted to Peter, the church's more peaceable leader. Since Jupiter is sacred to the cult, her goal is thwart the Jupiter Solarization Project's plan to convert the planet into a fusion explosion that will nudge the black hole onto a different trajectory.
- Gunhed: Kyron-5, a malevolent supercomputer attempting to secure the extremely powerful energy source Texmexium, the key to its planned offensive to wipe out humanity.
- My Soul Is Slashed: Ryūzaburō Kitahara, who is not only responsible for the faulty drugs Takashima Pharmaceutical Co., Ltd. produced but was the one behind Shūtarō Ishikawa's "accident." When he learns that Ishikawa has returned from the dead (as a vampire, unbeknownst to him), he dispatches hitmen to finish the job.
- Mikadroid: Nabeshima, a Cyborg supersoldier completed by the Imperial Japanese Army in the final days of World War II, then trapped underground and forgotten following a B-29 raid. When he reactivates in the present day, he starts going on an indiscriminate murder spree in a discotheque's underground parking structure.
- Yamato Takeru: Tsukuyomi, the evil god of the underworld, spends most of his time trapped in ice in space, and so the Big Bad duties are shouldered by the evil magician Tsukinowa, a fragment of Tsukuyomi who seeks to prepare the way for his master's return by killing Yamato Takeru. While he fails to finish off the young prince, he does succeed in acquiring the Ame-no-Murakumo-no-Tsurugi to restore Tsukuyomi's full power. It is upon said return that Tsukuyomi actually becomes the Big Bad, transforming into Orochi in the climax.
- The Hypnotist: The malevolent supernatural entity Rat awakens, or summons, within Yuka Irie through his hypnotism. It plants post-hypnotic triggers in people that cause them to violently kill themselves.
- Pyrokinesis: Masaki Kogure, head of a gang of vicious teenage delinquents, is the one who rapes and murders protagonist Junko Aoki's love interest's sister, and he's leading his group on a whole slew of grisly murders that are recorded as snuff films. However, he's actually being enabled and instructed by Yoshihiro Hasegawa, chief of the Tokyo Metropolitan Police Department's Criminal Investigation Bureau. A Knight Templar who started out killing criminals, he grew to loathe victims as well as those who hurt others and ultimately degenerated into a sadist. Intoxicated by his ability to have people killed on his orders, he organized a clandestine organization known as the "Guardians" to carry out his whims.
- Onmyōji: Dōson, the head of the imperial court's Bureau of Onmyō, and a nihilist who secretly finds pleasure in stoking hatred and causing strife. He forms a Big Bad Duumvirate towards the end of the film when he releases and is possessed by the powerful ghost of Prince Sawara, the brother of a previous emperor who was falsely accused of treason and killed, and who thus bears a grudge against the imperial line and the capital city of Heian.
- The Returner: There's a Big Bad Ensemble between the alien Daggra that are on the verge of wiping out all of humanity in the future and Liu, a Triad boss intent on acquiring a crashed Daggra starship and its juvenile pilot in the present. Liu's Japanese lieutenant, the hot-tempered and psychopathic Mizoguchi, however, serves as The Heavy for the film, and he ultimately supplants Liu as the second Big Bad and turns out to be the cause of the Daggra's genocidal war against humanity, as, in the original timeline, he's the one that kills the child Daggra.
- Onmyōji 2: Genkaku, the chief of Izumo prior to its almost complete extirpation by the Yamato. Consumed by revenge and the desire to restore Izumo, his plan revolves around turning his son Susa into the reincarnation of Susanoo, who will then destroy the Yamato and become the new king of Izumo.
- Infection: Creepy Dr. Kiyoshi Akai, who turns out to not be a doctor at all, but the ghost of the patient the hospital staff accidentally killed through misdosage. Angry not because they caused his death, but that they're trying to cover it up, he becomes a sort of memetic infection that spreads through sleep and preys upon his victims' guilt. Maybe. The film is a heck of a Mind Screw.
- One Missed Call 2: Killed after she cursed several of her fellow villagers to death (though she may have only predicted their deaths due to a waterborne disease), Vengeful Ghost Li Li kills people via a curse transmitted through their cell phones and was, in fact, responsible for the death of Mimiko Mizanuma, whose ghost is the previous film's Big Bad. It also turns out Mimiko is not quite absent in this film either, and is targetting protagonist Takako Nozoe and her husband Chen Yuting.
- Lorelei: The Witch of the Pacific Ocean: Ryōkitsu Asakura, the mid-ranking officer of the Imperial Japanese Navy General Staff who planned the mission to Tinian in the first place. Embittered at his higher-ups for leading the country into a devastating war and their not properly paying for it, Asakura actually arranges to hand over Paula Atsuko Ebner, the titular Lorelei, to the United States, with the proviso that the Americans DO nuke Tokyo. Only this way, he believes, can Japan's irreponsible leadership be purged and a new Japan emerge.
- One Missed Call: Final: Asuka Matsuda, a schoolgirl who seeks Revenge on her class for her savage bullying by transmitting a curse through their cell phones. Except she's actually in a coma and possessed by the original Big Bad, Mimiko Mizanuma, who is using her to spread her curse.
- Monkey Magic: King Gold Horn and King Silver Horn, two powerful demon brothers who've conquered the land of the Tiger People and are seeking an orb that will release a monster whose miasma will blot out the Sun.
- K-20: Legend of the Mask: Power-hungry master thief K-20, aka Detective Kengorō Akechi, who is trying to steal a Weapon of Mass Destruction, the Tesla device, and frames circus acrobat Heikichi Endō as part of his plan.
- 20th Century Boys 1: The Beginning of the End: Friend, the charismatic but monstrous cult leader who orchestrates an elaborate plan based on the childhood fantasies of Kenji Endō and his gang, a plan whose first stage involves successfully taking over Japan.
- 20th Century Boys 2: The Last Hope: Friend again, who executes the next part of his plan, faking his resurrection from the dead, unleashing a deadly engineered virus worldwide, and using his messianic status and possession of a vaccine to rule the world. Once again, he succeeds.
- 20th Century Boys 3: Redemption: Still Friend, who sets into motion the final part of his plan, to wipe out most of mankind, leaving only a remnant he would rule over. His true identity is finally revealed to be Tadanobu Katsumata, a childhood acquaintance of Kenji and his friends lashing out at the world in a rage stemming from childhood loneliness, bullying, and a degree of loss of sense of self. It at this final stage of the plan that he is finally defeatednote .
- Space Battleship Yamato: Desla, the leader of the alien Gamilas trying to exterminate humanity and terraform Earth to their liking. Desla more properly is Gamilas, the aggressive aspect of the alien species' Hive Mind that, unlike its more peacable half Iskandar, wants to escape its homeworld's destruction by colonizing Earth.
- Gantz: The closet thing to a Big Bad is Gantz itself, which resurrects recently deceased humans to hunt down dangerous (when provoked) but apparently non-hostile aliens hiding out on Earth. Whereas the manga would reveal that Gantz, while sadistic and capricious, is genuinely helping humanity, Gantz's reasons for doing this in the film are inscrutable.
- Gantz: Perfect Answer: Gantz again, for the reasons given above, but there's a second Big Bad in the form of the leader of the shapeshifting Men in Black aliens, who want revenge on Gantz after one of its previous teams murdered their friends.
- Attack on Titan: There's a Big Bad Ensemble between Kubal, director of Paradis' military, and Shikishima, captain of the Scout Regiment, though it is not until the second movie that the fact they are the Big Bads is revealed, along with their motives and plans.
- Parasyte 2: The first Big Bad is Takeshi Hirokawa, a key member of Ryōko Tamiya's parasite network and the city's new mayor. Frustrated by Tamiya's goal for peaceful coexistence with humanity, he operates behind her back and ultimately supplants her in a coup with the intent of pursuing more aggressive relations with humanity. Hirokawa's actually human, but he hates humanity for its deletorious effects on the biosphere, and sees culling most of the human population as the only way to restore ecological balance. As Tamiya predicted, Hirokawa's tactics end up getting him and all but one of the parasites in the network wiped out. The survivor, Gotō, becomes the final Big Bad. His ultimate goal is to Kill All Humans, having inherited the misanthropic mindset of the man whose body he killed to possess, but his immediate objective is to kill the heroes Shin'ichi Izumi and Migī.
- Attack on Titan: The End of the World: Shikishima and Kubal are revealed to be the Big Bads. Shikishima despises the repressive regime that rules Paradis, and wants to overthrow it and achieve absolute freedom by destroying the two intact Walls protecting the city from the Titans. This will mean the deaths of countless innocent people, but Shikishima despises them too for their perceived passivity. Kubal, on the other hand, takes the opposite position. He believes that humanity cannot survive outside the Walls, and that the controlling government and necessity to share resources eliminates the conflict that perennially plagued humanity. He also is revealed to be the Colossal Titan that broke the outermost Wall in the first place, causing the events of the story, in order to reinforce the population's fear of Titans to quash dissent and end any desire to live outside the Walls.
- Tokyo Gore Police: The Chief of Police, who killed the Key Man's father to privatize the police, thus creating the Engineer problem in the first place.
- The Toolbox Murders: Vance Kingsley, a fanatic killing "impure" women after his daughter dies.
- The Tooth Fairy (2006): Elizabeth Craven, a deformed Wicked Witch who keeps children's souls bound to Earth via their teeth.
- Tormented (2009): Bradley, who tormented Darren into suicide and started his vengeance quest in the firs place.
- Torso: Franz, a mad strangler hunting down a witness.
- The Torture Chamber of Dr. Sadism: Count Frederick Regula, a vampire torturing women for immortality.
- Touch of Evil: Hank Quinlan, who frames those he believes to be criminals for crimes and sets out to ruin Mike Vargas' life once he starts to suspect him of wrongdoing.
- Tourist Trap: Mr. Slausen, a Serial Killer with psychic powers.
- The Town: Fergus Colm, Doug's employer who forces him to go through with the Fenway Park heist under the threat of killing Claire.
- The Town That Dreaded Sundown (1976): The Phantom Killer, a hooded madman who kills couples out at night.
- The Toxic Avenger
- First film: Mayor Peter Belgoody, whose corruption directly leads to Tromaville being a Wretched Hive.
- The Toxic Avenger Part II and III'': The Chairman of Apocalypse Inc., who wants to take over Tromaville.
- Citizen Toxie: The Toxic Avenger IV: Noxious Offender, Toxie's evil alternate self who takes over Tromaville while he's stuck in Amortville.
- Toys: General Leland Zevo, a paranoid military commander who wants to take his nephew's toy company and use it to indoctrinate children into perfect soldiers.
- Trading Places: Randolph and Mortimer Duke, a pair of siblings who miserly oversee an estate and decide to ruin Winthrope's life for fun.
- Training Day: Detective Alonzo Harris. The entire plot is because of him killing a courier for the Russian Mafiya, and the "training day" with Jake is a means of securing the money to pay them off and set up Jake as his fall guy.
- Trancers: Martin Whistler, who went back in time to destroy the future government that arrested him.
- Transcendence: Bree, the leader of RIFT, who wants to destroy the world's technology to become a dictator.
- Transformers
- Transformers Film Series:
- Transformers (2007): Megatron, the leader of the Decepticons who's after the AllSpark and aims to use its power to destroy Earth.
- Transformers: Revenge of The Fallen: The Fallen, the true founder of the Decepticons who attempted to destroy humanity long ago and is back to finish what he started.
- Transformers: Dark of the Moon: Sentinel Prime, Optimus' mentor who betrayed the Autobots in favor of the Decepticons and intends to drag Cybertron to Earth and enslave the remnants of humanity.
- Transformers: Age of Extinction: Harold Attinger, the founder of Cemetary Wind who wants to eradicate all transformers and convert their husks into his own personal army all out of Paranoia, Greed and Fantastic Racism, under the false guise of protecting humanity.
- Transformers: The Last Knight: Quintessa, a Creator who intends to destroy Unicron to save Cybertron, even though that means Earth's destruction.
- Bumblebee: Shatter and Dropkick, a duo of Decepticons sent to hunt down and kill Bumblebee before attempting to contact the Decepticon army to destroy Earth.
- Transformers Film Series:
- The Transporter:
- First film: Wall Street and Mr. Kwai, the heads of the human trafficking organization who want Frank dead once he finds out about their business.
- Transporter 2: Gianni Chellini, a crime lord who intends on killing the Billings family and any politican who opposes his superiors' drug dealing activities.
- Transporter 3: Johnson, who forces Frank to do his dirty work under the threat of detonating an explosive bracelet on him.
- The Transporter Refueled: Arkady Karasov, the leader of the Russian sex trafficking ring.
- Traxx: Aldo Palucci, a crime boss singlehandedly making a city a Wretched Hive.
- The Treasure of Silver Lake: Colonel Brinkley, a ruthless bandit seeking the titular treasure.
- The Trial of the Chicago 7: Judge Julius Hoffman. He shows open bias against the defense and rules one-sidedly for the government. His ordering Bobby Seale held bound and gagged in open court appals even lead prosecutor Schultz.
- Trick or Treat: Sammi Curr. He's the ghost of a Satanic rockstar who comes back from the dead via The Power of Rock.
- Trilogy of Terror:
- "Julie": Julie Eldridge, a woman who manipulates predator into thinking she's the perfect victim before killing them for fun.
- "Therese and Millicent": Therese Loramont, Millicent's sister who's actually a split personality who spends the segment tormenting and abusing her.
- "Amelia": He Who Kills, an evil spirit trapped inside a Zuni fetish doll.
- Troll (1986): Torok, a troll seeking to free his brethren and set them upon the human world.
- Troll 2: Creedence Leonore Gielgud, a goblin queen who turns people into plants for food.
- The Troll Hunter: Finn Haugen, a ruthless government agent covering up the trolls.
- Tropic Thunder: Tran, the leader of the Flaming Dragon gang.
- Troy: Agamemnon, who seeks to conquer Troy and uses Helen's abduction as an excuse to sack the city.
- True Grit: Lucky Ned Pepper an outlaw gang leader harboring Tom Chaney. However, it is Tom Chaney himself, the murderer of Mattie Ross' father, who is the target that Mattie, Rooster, and La Boeuf are after.
- Rooster Cogburn: Hawk, the leader of the gang of criminals that killed Reverend George Goodnight, leading his daughter, Eula, to enlist Rooster to help her track him down and bring him to justice.
- True Romance: Vincenzo Coccotti, who's after Clarance and Alabama for stealing his cocaine.
- The Truman Show: Christof, the creator of the titular show overseeing and manipulating Truman's life.
- Tucker & Dale vs. Evil: Chad, the leader of the college kids who wants to kill Tucker and Dale under the mistaken belief that they kidnapped Allison.
- Turbo Kid: Zeus, a warlord who rules his post-apocalyptic world with an iron fist.
- Turbulence: Ryan Weaver, a incarcerated Serial Killer who takes over the plane transporting him before attempting to crash it and kill everyone inside.
- Twister: The tornadoes are textbook examples of the "omnipresent situation" variety of this trope. Doctor Jonas Miller appears as a more tangible villain, but since he doesn't do anything particularly "evil" and doesn't add to the plot or conflict the way the tornadoes do, he comes off as rather superfluous.
- Twitches: Thantos, the evil uncle of Alex and Camryn who vows to use the darkness to conquer all of Coventry.
- Two Thousand Maniacs!: Mayor Joseph Beckman, who leads his town in murdering Northerners to avenge their massacre by Union soldiers.
U
- UHF: R.J. Fletcher, the head of Channel 8 who wants to shut down George's show.
- Unbreakable: Elijah Price, who engineered disasters to find someone like David, then mentored him in becoming a superhero, so Elijah himself could become a villain in opposition, thus validating his purpose in life.
- Split: The Beast, Kevin's secret superpowered, cannibalistic 24th personality that his other personalities work to summon.
- Glass (2019) has a Villain Team-up between Elijah Price/Mr. Glass and Kevin Crumb/The Horde, specifically the Beast, though the true villain is revealed to be Dr Ellie Staple, who heads the Ancient Conspiracy to prevent superhumans from becoming known to the world.
- Unbroken: Mutsuhiro "The Bird" Watanabe, the head of the Japanese prison war camp Louie's trapped in.
- Under Siege: William Strannix, a CIA agent gone rogue who seizes control of the Missouri.
- Under Siege 2: Dark Territory: Travis Dane, a former government scientist ploting to takeover an orbital satellite-based superweapon, and use it to destroy the United States eastern seaboard.
- Underworld (2003):
- First film: Viktor, one of the three Vampire Elders who wants to exterminate the lycan race.
- Underworld: Evolution: Marcus, the third Vampire Elder who seeks to unleash his brother from prison and create a new species of immortals.
- Underworld: Rise of the Lycans: Viktor (again).
- Underworld: Awakening: Dr. Jacob Lane, chief scientist at Antigen [[spoiler:who's secretly a Lycan out to wipe out vampires and have Lycans become dominant.
- Underworld: Blood Wars: Marius, the Lycans' new leader who seeks to use Eve's blood to increase his power, and Semira, one of the leaders of the Eastern Coven, who plots to take over the coven and make herself a Hybrid.
- Unhinged (2020): Tom Cooper, who sets out to ruin Rachel's life because she honked at him when he stalled at a green light.
- Universal Horror:
- The Hunchback of Notre Dame (1923): Jehan, who wants to take Esmeralda for himself and is willing to cut down anyone that gets between them.
- The Phantom of the Opera (1925): Erik, The Phantom of the Opera, who causes mayhem and kills the staff of the Paris Opera House in order to make the object of his desire, Christine Daaé, a star.
- The Cat and the Canary: The Cat/Charlie Wilder, the next in line for Cyrus West's fortune who attempts to drive Annabelle insane in order to get it.
- Dracula (1931): Count Dracula, a feared Transylvanian vampire moving to London for new prey.
- Frankenstein (1931): Frankenstein's Monster's Obliviously Evil rampage drives the conflict.
- The Mummy (1932): Imhotep, who intends on sacrificing Helen in order to revive his lost love and is willing to kill anyone that stands in his way.
- Murders in the Rue Morgue: Dr. Mirakle, a Mad Scientist killing women to do experiments with ape blood.
- The Old Dark House (1932): Morgan and Saul Femm.
- The Invisible Man (1933): Dr. Jack Griffin/The Invisible Man, who lost his mind after accidentally turning himself invisible, leading him to go on a murderous rampage.
- The Black Cat: Hjalmar Poelzig, the leader of a satanic cult who plans to sacrifice Joan in a ritual.
- The Raven (1935): Dr. Richard Vollin, who tries to destroy Jean Thatcher and her family as revenge for spurning his advances.
- Werewolf of London: Dr. Wilfred Glendon, who's transformed into a werewolf and is driven by his instincts to kill, and Dr. Yogami, who turned Glendon into a werewolf in the first place and wants the one potential cure for himself.
- Bride of Frankenstein: Doctor Septimus Pretorius, whose need to create life drives him to kidnap Dr. Frankenstein's bride, Elizabeth, in order to coerce him into making the monster a mate.
- Dracula's Daughter: Countess Marya Zaleska, who after attempting to cure her vampirism, resorts to luring psychiatrist Jeffrey Garth into Transylvania so she can turn him into a vampire and make him her mate.
- The Invisible Ray: Dr. Janos Rukh, who loses his mind and starts murdering those he deems to have wronged him with the killing touch he gained from a meteorite he was studying.
- Son of Frankenstein: Ygor, who uses the Monster to get revenge on the townspeople who had him hanged.
- The Invisible Man Returns: Richard Cobb, who framed Geoffrey for murder to take over his coal mining business.
- The Invisible Woman (1940): Blackie Cole, who wants to steal Professor Gibbs' invisibility device.
- The Mummy's Hand: Kharis and Professor Andoheb, both of whom intend on killing the archaeologist team for treaspassing on the former's tomb.
- The Wolf Man (1941): Larry Talbot, who's cursed to become the titular Wolf Man and goes on a rampage.
- The Ghost of Frankenstein: Ygor, who wants to have his brain put into the Monster so he can live forever.
- Invisible Agent: Baron Ikito, Conrad Stauffer, and Karl Heiser, who are after the invisibility formula.
- The Mummy's Tomb: Kharis and Mehemet Bey, who are out to kill the members of the Banning expedition and their families.
- Frankenstein Meets the Wolf Man: Frankenstein's Monster, The Wolf Man, and Dr. Mannering, all of whom end up terrorizing the village of Vasaria.
- House of Frankenstein: Dr. Gustav Niemann, who uses the Monster and the Wolf Man to get revenge on those who got him imprisoned.
- The Invisible Man's Revenge: Robert Griffin, who takes the invisibility serum and uses it so he can commit crimes.
- The Mummy's Ghost: Kharis and Yousef Bey, who search for the reincarnation of the former's lover, Ananka, and make her his bride.
- The Mummy's Curse: Kharis and Dr. Ilzor Zandaab, who once again search for Ananka, killing those who stand in their way.
- House of Dracula: Count Dracula, who wants to turn nurse Milizia into a vampire and take her as his bride, and Dr. Franz Edelmann, who becomes a murderous monster as a result of receiving a blood transfusion from the Count.
- The Brute Man: Hal Moffat/The Creeper, who's out to murder his old university classmates, whom he blames for his disfigured face.
- She-Wolf of London: Martha Winthrop, who's behind a series of murders and manipulates Phyllis into believing that she's the killer.
- Abbott and Costello Meet Frankenstein: Count Dracula, who wants Wilbur's brain so he may use it to make the Monster more obedient.
- Abbott and Costello Meet the Invisible Man: Morgan, who's behind the murder of Tommy's manager and frames him for it, with Lou and Bud trying to prove he's the true culprit.
- Abbott and Costello Meet Dr. Jekyll and Mr. Hyde: Dr. Henry Jekyll / Mr. Edward Hyde, the killer behind a string of murders across London who Tubby and Slim attempt to apprehend.
- It Came from Outer Space: Sheriff Matt Warren, who wants to kill the peaceful alien invaders under the belief that they're dangerous.
- Creature from the Black Lagoon: The Gill-Man, who's out to kill the expedition team invading his habitat and mate with Kay.
- Revenge of the Creature: The Gill-Man, who wreaks havoc after being captured and experimented on.
- Tarantula!: The Tarantula rampaging across the small Arizona town.
- The Deadly Mantis: The Mantis who's unleashed from the Arctic ice caps and goes on a rampage.
- The Incredible Shrinking Man: Butch the Cat and the Spider, who spend the film persuing and attempting to eat Scott.
- The Thing That Couldn't Die: Gideon Drew, who wants to reuinite his head with his body so that he can use the full extent of his powers.
- The Leech Woman: June Talbot, who regularly sacrifices men in order to maintain her youth and beauty.
- Unlawful Entry: [[Killer Cop Pete Davis], a local cop who develops an obsession with Karen Carr, which leads him to ruin the life of her husband and attempt to kill the both of them.
- The Untold Story: Wong Chi-hang, who killed his boss's entire family to take his restaurant and disposes of the bodies by making them into BBQ buns.
- The Untouchables (1987): Al Capone, the source of all of the corruption and violence in Chicago.
- Urban Legend: Brenda Bates, the identity of the killer murdering college students by recreating different urban legends..
- Urban Legends: Final Cut: Professor Solomon, the Copycat Killer murdering students.
- Urban Legends: Bloody Mary: Mr. Owens, the one responisble for killing Mary and making her the monster she is now.
- The Usual Suspects: Keyser Soze though we never see him until the end of the film and revealed to be Roger "Verbal" Kint.
- Utu: Te Wheke, who terrorizes and slaughters the British invaders after they destroy his village, and Colonel Elliot, who goes to great lengths to hunt Te Wheke down.
V
- While the VHS franchise is an anthology with each segment having it's own Arc Villain, the framing device segments also have their own villainnote .
- The first film has Gary, Zak, Rox and Brad, who break into the house containing the tapes in order to steal one for an anonymous contract.
- V/H/S/2: Kyle, who seeks to make a cursed tape of his own.
- V/H/S: Viral: The unamed entity posessing Iris and controlling the cursed tapes, planning to upload the curse online.
- SiREN: Mr. Nyx, a Sinister Minister who's running a hedonistic business that uses demons like Lily as slaves, with Lily herself serving as The Heavy.
- V/H/S/94: [[spoiler:Petro and Nash are revealed to be members of Snuff Film cult and manipulate the SWAT team in order to create the "Best film yet".
- Kids vs. Aliens: The Aliens from V/H/S/2's "Slumber Party Alien Abduction", now revealed to be abducting humans to use them as fuel.
- V/H/S 85: Rory, a mysterious shapeshifting being getting studied by the scientists.
- Valentine: Jeremy Melton, alias Adam Carr seeks revenge on four young women who framed him for rape and incited a Gang of Bullies into beating him.
- Valerie and Her Week of Wonders: Tchor the Polecat, the vampire who keeps trying to steal Valerie's youth.
- Valkyrie: Adolf Hitler, the leader of the Nazi Party and the wartime German government.
- The Vampire: The Vampire, out hero's bloodsucking Superpowered Evil Side.
- The Vampire Bat: Dr. Otto von Niemann, a Mad Scientist seeking human blood to perfect the creation of life.
- The Vampire Doll: Dr. Yamaguchi, who killed most of the Nonomuras and is responsible for Yuko's vampirism.
- Vampirella: Vlad Dracula, who killed Vampirella's father and is responsible for Earth's vampire plague.
- The Vampire Lovers: Mircalla Karnstein, a Lesbian Vampire seeking her latest prey.
- Vampire's Kiss: Peter Loew's slow descent into violent insanity drives the plot.
- Van Helsing: Count Vladislaus Dragiola. He is the primary threat of the movie and the lord of all the antagonistic monsters. He wants the Valerious family to die off so they're no longer a threat to him, and he wants to dominate the world with his newborn breed.
- Venom (2018): Carlton Drake and Riot. Originally working independently of each other, they team up near the climax to annihilate mankind by bringing more symbiotes to Earth.
- Veronica Guerin: John Gilligan, a powerful drug lord that Veronica attempts to expose.
- Veronica Mars: [[spoiler:Stu "Cobb" Cobbler. He manipulated the people on the boat into covering up Susan's death, blackmailed them, killed Carrie, sexually extorted Gia, and eventually killed her.
- Versus: The unnamed necromancer who wishes to take over the Forest of Resurrection for his own power.
- Vice (2015): Julian Michaels is the head of the Vice Corporation and the one behind all the misery the artificials are put through.
- Vidocq: The Alchemist revealed to be Etienne Boisset, who's been murdering Paris citizens for centuries and using their souls to fuel his immortality.
- The Village (2004) has the Elders, who dress up as monsters and scare those who attempt to leave the village.
- The Visit: The Grandparents, who are actually escaped mental patients that killed the real grandparents and stole their identities.
- Vlad Tepes: Sultan Mehmed II of the Ottoman Empire, who is on a path of conquest and has just reached Wallachia.
- The Void: Dr. Richard Powell, an insane cult leader seeking to conquer death.
W
- Waar: Ramal, a mercenary plotting an attack on Pakistan.
- The Wailing: The unnamed Japanese hermit turns out to be the dark force stalking the town.
- Wait Until Dark: Roat, who spends the film psychologically torturing Susy.
- A Walk Among the Tombstones: Ray and Albert, who have been kidnapping and holding the loved ones of criminals for ransom before murdering them.
- Wall Street: Gordon Gekko, an unscrupulous corporate raider and an Evil Mentor to Bud Fox.
- Wall Street: Money Never Sleeps: Bretton James, the head of Churchill Schwartz and Gekko's chief rival.
- War of the Worlds (2005): The Martians, who are out to terraform the Earth.
- Warriors of the Wasteland: One, a raider who wants to slaughter everybody on Earth.
- War Witch: Great Tiger, leader of the militia that conscripted Komona.
- Watchmen: Adrian Veidt/Ozymandias, who masterminds the destruction of several major cities in a bid to unite the world's nations.
- Waterworld: The Deacon. He's in charge of a band of pirates known as Smokers who regularly terrorize folks and plans on using Enola to get him and his pirates to dry land (as the tattoo on her back is actually a map), and ends up chasing The Mariner across the ocean for her.
- Way of the Dragon: The Boss, leader of the Mafia group harassing the restaurant.
- We Are Still Here: The Darkness, an Eldritch Abomination that demands sacrifices every 30 years.
- The Web (1947): Andrew Colby, a businessman willing to kill to cover up his corruption.
- The Werewolf of Washington: Jack Whittier, the White House press secretary who's afflicted with lycanthropy.
- Werewolves of the Third Reich: Dr. Josef Mengele, the Nazi Mad Scientist making Nazi werewolves.
- Werewolves on Wheels: One, a Satanic cult leader who turns bikers into werewolves for interrupting a sacrifice.
- Westworld: The Gunslinger, a killer malfunctioning animatronic hunting down John and Peter.
- What Have You Done to Solange?: Professor Bascombe, a vengeful Serial Killer stalking a girls' school.
- What Keeps You Alive: Jackie, who spends the entire film trying to kill her wife.
- Whispering Smith: Barney Rebstock, a powerful local Rancher, is also the head of the gang of train robbers that Smith is hunting. Smith is convinced Rebstock is the mastermind behind the gang, but is having trouble proving it.
- White House Down: Martin Walker, the head of the US Secret Service who's in charge of the terrorists taking over the White House. However, it's actually a conspiracy made by him and Eli Raphelson, the Speaker of the House responsible for hiring the terrorists in the first place.
- The Wicker Man (1973): Lord Summerisle, head of a pagan village that commits human sacrifice to maintain their crops.
- The Wild Angels: Heavenly Blues, a Villain Protagonist biker gang leader.
- Wild Things: Suzie Toler, a manipulative teenager out to destroy a rich family.
- Wild Wild West: Arliss Loveless, a Confederate officer who intends to take over the United States using his steampunk machinery.
- Wishmaster: Djinn, a genie who willfully corrupts the wishes of his masters and plans on unleashing his kind upon humanity once his wisher grants three wishes.
- The VVitch: Black Phillip, the family goat, who's secretly the demon setting the witches upon everybody.
- Witchboard: Carlos Malfeitor, an executed murderer who wants to return to the land of the living to keep killing.
- The Witches Hammer: Madeline Renoir, a vampiress who seeks to bring Hell on Earth.
- Witchfinder General: Matthew Hopkins, a sadistic conman mastermind witch hunts for money.
- Witchouse: Lilith Le Fey, an undead Wicked Witch seeking revenge on the descendants of her killers.
- The Wizard: Lucas and Putnam. Lucas is the main rival of Jimmy at the video game tournament, while Mr. Putnam is the creepy and greedy private investigator/bounty hunter hired to find the escaped kids and resorts to unscrupulous tactics to capture them.
- Wizards of the Demon Sword: Lord Khoura, who seeks the Blade of Aktar to cloak the world in darkness.
- Wolf Creek: Mick Hunter, a killer, rapist, and torturer who preys upon tourists visiting the Wolf Creek area.
- WolfCop: Mayor Bradley is the leader of the secret reptilian conspiracy to control the town.
- Wolfen: The Alpha of the Wolfen pack responsible for a series of murders.
- The Wolfman (2010): Sir John Talbot, the werewolf that bit Lawrence, and also killed Lawrence's brother and mother.
- Wolfman: Reverend Leonard, the Satanist minister who cursed the Glasgows with lycanthropy.
- The Woman in Black: The Woman in Black, a vengeful ghost terrorizing the village's residents.
- Would You Rather: Shepard Lambrick, a wealthy man forcing poor folks into playing a sadistic game.
- Wrestlemaniac: El Mascarado, a luchador made of other wrestlers' body parts and driven to kill everything he sees.
- Wyrmwood: The Captain, a Well-Intentioned Extremist willing to commit human experimentation to cure the zombie plague.
X
- Xx X: Yorgi, the leader of Russian terrorist group Anarchy 99, who have gained possesion of a deadly bioweapon.
- Xx X State Of The Union: George Deckert, the Secretary of Defense plotting to overthrow the U.S. government to preventthe dismantlement of military bases
- Xx X Return Of Xander Cage: Jane Marke, who after pretending to aid Xx X, steals Pandora's Box for herself, giving her control over all of the world's military satellites, and attempts to kill the team once they've outlived their usefulness.
Y
- Yojimbo: Ushitora, who starts a gang war by betraying his old boss.
- Sanjuro: Superintendent Kikui, who has kidnapped a political rival to make him commit seppuku.
- You Don't Mess with the Zohan: Grant Walbridge, who wants to drive out the residents of the neighborhood that he wants to tear down in order to build a mall.
- You Nazty Spy!: Moe Hailstone, a dictator who takes over the nation of Moronika.
- Young Sherlock Holmes: Eh-Tar/Professor Rathe, the fencing master, is the leader of the cult of Rame Tep and undertakes a Roaring Rampage of Revenge against the British academics who killed his parents with the help of his sister Mrs. Dribb. After surviving the final duel, Rathe takes the alias Professor James Moriarty, and plagues Sherlock Holmes for years to come.
- Youth of the Beast: Nomoto Tetsuo, the Yakuza boss who is responsible for Jo's partner's murder.
- Yuma: Mules McNeil, the true source of all of the corruption in Yuma.
Z
- Z: The unnamed General orders the Deputy's assassination and the coverup thereof.
- Zathura: The Zorgons, a species of bloodthirsty reptilian aliens who decide to loot the Budwings' floating house, with their Killer Robot as Dragon-in-Chief.
- Zero Dark Thirty: Osama bin Laden, who Maya deadset on either capturing or killing for the evils he and his terrorist organization has caused.
- Zodiac: The Zodiac Killer, a hooded madman stalking San Francisco.
- Zombie Cop: Dr. Death, a voodoo priest plotting to zombify a group of schoolchildren.
- Zombie Strippers!: Dr. Chushfield, who started a zombie outbreak for military research purposes.
- Zombie Wars: George, who trained the zombies to take slaves.
- Zoolander: Jacobin Mugatu, who plans on brainwashing Mark into assassinating the Prime Minister of Malaysia so he can continue to use cheap Malaysian child labor.
- The Zorro films starring Antonio Banderas:
- The Mask of Zorro: Don Rafael Montero, the former corrupt governor of New Spain who intends to buy California. He is the Arch-Enemy of Zorro's mentor Don Diego de la Vega, who was imprisoned by Rafael.
- The Legend of Zorro: Count Armand, the head of the Knights Of Aragon, who intend on overthrowing the United States.