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Anime and Manga
- In Ghost in the Shell: Stand Alone Complex 2nd Gig the "Individual Eleven" virus infected people who read a certain essay, becoming terrorists and (aside from Kuze) eventually committed suicide.
- In Higurashi: When They Cry, Hinamizawa Syndrome is caused by some sort of parasite that is initially compared to a virus in the sixth arc. That is the only arc where it is referred to as a virus, and the person who called it that was an Unreliable Narrator. The arcs after it tend to use the term parasite. Since there are many lifeforms (and viruses) that can theoretically be called parasites, it's a little uncertain what type of lifeform it actually is. That parasite, though, is what causes just about all of the madness that winds up killing so many people in the earlier arcs.
- In Magical Record Lyrical Nanoha Force, anyone who infected with Eclipse become an Eclipse Driver that knows nothing but kill to survive.
- An issue of The Authority had Apollo and Midnighter teaming up with alternate-universe versions of themselves to stop a killer meme: anyone who heard it would whisper it to the first person they saw and then commit suicide. They had to stop the meme from making its way to a TV studio, where it would be spoken on a live broadcast. The solution is to subject it to Executive Meddling, which renders it harmless.
- Also the Godhead arc, which featured a villain with the power to turn people into his slaves.
- In one Batman Story Arc, the villains try to release a meme virus into the population of Gotham which will give everybody a predisposition to addiction, thus causing chaos.
- Judge Dredd: The denizens of the evil dimension of Deadworld have once used Judge Anderson's mind to spread a psychic virus called Half-Life into Mega-City One, which caused widespread chaos as people spontaneously became either homicidal and suicidal (or both).
- Came up in a section of the Black Dossier, in which a descendant of Fu Manchu tried to release an (ancient Aztec) linguistic virus into a Massachusetts spaghetti restaurant to perpetuate a feud between his family and Professor Moriarty's. Makes far, far less sense in context.
- In Planetary, the Big Bad's power is seemingly that his mind expands and 'infects' other minds near himself, causing them to start to think the same way and become, well, him. It ends up becoming an Informed Ability because we never see him use it.
- Transmetropolitan alludes to things like this at times, although details for how they work are never given. A Canibalism Meme is mentioned as one point, for instance.
- An X-Men story during an arc where they were fighting vampires dealt with their human allies quarantining and attempting to cure a group of humans infected with one by a vampire that made them want to be drained by him. They were consciously aware of their condition but will physically act to achieve it all the while voicing praise. It took them discovering it was mental for them to gain the help of a resident telepath to make any progress.
- In This Bites!, it's stated that the reason for the crew's out-of-character moments on the Secret Island, leading to their bonds fracturing, is all due to Lily Carnation's spores. And the more human someone is, the more they are susceptible to it.
- The only ones not as affected were Luffy, Conis, Soundbite, and Robin, one of whom is a Skypiean and the others being Devil Fruit users.
- Chopper, Boss, and the TDWS's reactions are not shown due to them being off-camera, and the latter five had already been caught by Lily Carnation.
- The only ones not as affected were Luffy, Conis, Soundbite, and Robin, one of whom is a Skypiean and the others being Devil Fruit users.
- Lulu's Bizarre Rebellion: The stand Hey Jude acts as this, inflicting Mental Time Travel on anyone effected. Give in to the temptation to change something you know will happen, and you become a new user/carrier of the stand.
- In the film Pontypool, the English language becomes infected with a virus that drives English-speakers crazy.
- Project Itoh: Genocidal Organ involves the hunt for an American linguist called John Paul who has discovered a language of genocide. John Paul appears in Third World countries, translates the language into a local dialect (to limit its effect so it won't spread worldwide) and six months later the country implodes into ethnic conflict.
- "Hostess", a short story by Isaac Asimov, suggests that humans die of old age because they're infected by a parasite that exists in their mind (it having adapted to not even needing a body). By the end, it's indicated that many of humanity's unusual traits are caused by the existence of the parasite.
- Greg Bear's novel Vitals features bio-engineered viruses that manipulate their victims hormones and brain chemistry. Though the viruses themselves are undirected, the evil government conspiracy will "dose" people with different strains of the virus, in combination with setting up fake evidence, in order to discredit anyone who threatens to expose the conspiracy. One character, an investigative author who starts getting too close to the truth, is infected with a compulsive anti-semitism virus that causes him to lose his reputation. Later on, another character is made to murder by use of a Hate Plague. The main character is also infected with a kind of "love" virus that renders him dopey and lovey-dovey with respect to a woman who's an agent of the conspiracy.
- John Barnes's Candle portrays the near-total success of one such virus, with only one remaining human being in the world who isn't infected. He has a different virus instead.
- In The Curious Incident Of The Dog In The Nighttime, the hero fantasizes of a virus ("like a computer virus") that spreads by people looking each other in the face. He is heavily autistic, and thus would survive such an epidemic.
- The Dresden Files has Nemesis, a mental plague that warps its victims to the service of the Outsiders. Dropped hints suggest that nearly every villain Dresden encounters may have been influenced by Nemesis.
- Neil Gaiman's poem Virus is an example of this, spread via a computer game.
- In Kathleen Ann Goonan's Queen City Jazz, part of her Nanotech Quartet series, a nanotech apocalypse sweeps across the world. There are several nanotech mind viruses going around, such as a virus that compels its user to go to one of several glowing spheres that have cropped up around the country. Further, the main character in Mississipi Blues is infected with a virus that compels her to abandon her old life and go rafting down the Mississippi river a la Huckleberry Finn.
- In one Homer Price story, the town gets infected with a song. A mysterious stranger comes to town and puts a record in the donut shop's jukebox, telling Homer and his friend not to play it. Of course they do, and they can't stop singing the song. They teach the song to others, who can't stop, and so on. Homer finally cures himself and the town by learning a different song (from a Mark Twain story), which makes them forget the first song, and once you pass that song on you forget it in turn. They send the one person infected with the new song out of town (she was going on vacation anyway) where they hope she'll teach it to someone else.
- Though the "culling song" in Chuck Palahniuk's Lullaby starts out as a lethal Brown Note, it eventually turns out that merely thinking about it can telepathically transmit it to someone else, making it a lethal Mind Virus.
- The third book in the Plague Year Series by Jeff Carlson, Plague Zone, features a mind virus that turns its victims into mindless husks that wander around, attempting to spread the virus to others (through airborne contact). They're not violent or anything, but insistent, shambling about like living zombies that don't eat or attack.
- Vernor Vinge's Rainbows End has the YGBM ("You Gotta Believe Me") virus, the hunt for which is a major plot of the book.
- Alastair Reynolds features these prominently in many of his novels. Century Rain has the "Amusica" virus that causes its victims to be unable to appreciate music (released as a demoralizing tool in a war). Chasm City has a communicable virus that inflicts its victims with the memories of a religious cult leader, giving them dreams of his life and causing stigmata to appear on their body.
- Peter Watts' Rifters Trilogy features several mind viruses, most notably "GuiltTrip", which forces its victims to always do "good" things (and severely punishes them, through pain or death, for failing to do so). A government agency purposefully infects its employess with GuiltTrip, reasoning that by doing so they do not have to worry about security anymore, since nobody would dare attempt to subvert or steal anything.
- Master of Space and Time by Rudy Rucker has a section where the heroes visit an alternate dimension full of "meme viruses". One of the characters is bitten by a "Jesus Lizard" and subsequently starts gaining messiah-like characteristics, along with growing out his hair and beard and wearing sandals all the time.
- There is a short story by Robert Sheckley where everyone on Earth learns to levitate. If, however, they ever doubt their ability to levitate, they lose it. Additionally, if one person sees another who is unable to levitate, it would automatically plant doubt into their minds as well, in effect becoming a fast-spreading virus.
- Snow Crash features a "biolinguistic virus" that renders its victims unable to communicate normally; anytime they try to talk, they just speak gibberish. Actually, it's a "metavirus". It has ways of converting between any format... malware... biological... neurological... linguistic... it's a wonder it could be stopped at all.
- Charles Stross has this in the novel Glasshouse. A virus called "Curious Yellow" has infected nearly all humans, via the ubiquitous and necessary Warp Gates that everyone uses to get around. It deleted memories of a recent war, giving pretty much everyone amnesia of that specific time period. Furthermore, it also deleted the memories of who released it and its full extent, meaning that nobody knows what else it might've done (or still be doing).
- In Those That Wake, this is how Man in Suit propagates himself.
- The 6th Extinction, the 10th title in James Rollin's Sigma Force series uses a Mind Virus as half of the villain's plot. A scientist creates a virus which destroys human's higher brain functions, reverting them to primitive animalistic behavior. At the same time he genetically engineers newer more violent animals. When both are released into the world, the now weak defenseless primitive humans will be easily picked off - letting "nature" take the planet back. Why bother with the virus? He didn't want his hands to be personally bloody with humanity's extinction, instead just rendering them without tools or reasoning and letting the animals do the job.
Live Action TV
- The Sickness in Lost, which is how The Man in Black recruits people to his side.
- The Star Trek: Voyager episode "Flashback" featured a virus in the form of a fake memory which spread through mental contact.
- Rather than having a single Joker, Gotham portrays Batman's future nemesis as more of a contagious idea, that infects numerous mentally-unstable Gothamites. Jerome Valeska was its "patient zero", and he passes it on to his twin Jeremiah and to hundreds of followers and "fans" of his rampages.
It feeds on the souls of the living.
And gets inside their minds.
Transforms their brains and their longings,
No consciousness it will find.
It feeds on their fears and emotions,
As it has for 2000 years
Its infected the Hindus, infected the Buddhists,
Kept them all in tears.
- Arena's "Contagion" concept album, about an apocalyptic psychic plague called the "blue fire" (or the Salamander Virus in an accompanying short story), a vicious Hate Plague. The protagonist was a Typhoid Mary who accidentally unleashed it on the world after foreseeing it, possibly even catching it from his foresight.
- The Game. It even has an antivirus!
- Some forms of the Exsurgent virus in Eclipse Phase simply alter how the victim thinks and/or add Psychic Powers, turning them into an unwitting pawn of the TITANS.
- In Paranoia, rumor has it that Viral Thought Patterns are behind Communism, Gamma Clearance, and Computer knows what else. (Rumors are treason. Report all rumors.)
- Mind Seed is a particularly nasty high-level Psionic power in Dungeons & Dragons 3.5 edition. It essentially transplants your own mind into the mind of a target, so that over the course of a week their thought patterns slowly transform into an exact mental duplicate of yourself at the time of implantation, including your personality and memories.
- The Maverick Virus and it's upgraded verson the Zero Virus from Mega Man X both infect Reploids and alter their programming, turning them into murderous psychopaths that still, for the most part, retain their memories and personality. The Sigma Virus, on the other hand, is a sentient entity that takes over other Reploids and appropriates their bodies.
- The entire premise of Lux-Pain revolves around fighting the spread of Mind Viruses, which cause people to either become insanely violent of suicidally self-destructive.
- The Radical-6 from Zero Escape Trilogy slows down thought processes of brain making everything around look like it's going on fast-forward and after a while causes severe urge to commit suicide.
- In Gifts of Wandering Ice there are so-called psi-profiles which when "assigned" to a person act as a gateway for very specific mind viruses.
- A Miracle of Science never goes into the exact details of how one normally contracts Science-Related Memetic Disorder in-universe (it's implied to be more of a "Go Mad from the Revelation" scenario, but never really discussed in-depth), but the Martians express concern that if one of their citizens contracts it, it might become one of these to them. It's only a theoretical possibility, but one they're understandably unwilling to test.
- In Schlock Mercenary, the Macarena is referred to by Reverend Theo Forbus as a "proven memetic infector."
- In Orion's Arm memetics are a mature science.
- The SCP Foundation has quite a few of these, which are classified under Memetic Hazards. "Infohazards" and "cognitohazards" are similar; where one starts and one ends is very much a Depending on the Writer thing.
- [[According to one article, human sentience is a sentient and pandemic Mind Virus, and as much as nobody wants to admit it in-universe, it's good that it is too or it would be wiped out by any number of things]].
- Mentioned in Young Justice. When Artemis drugs (and is subsequently attacked by) an evil telepath when on deep-cover, she uses this as an explanation for his odd behaviour.
- In Real Life, there's a sociological model known as Memetics, which posits that information and culture behaves like genetics ("meme" being the informational analogy of "gene")—that units of information transmit themselves from mind to mind. There's other competing sociological models, some of whose proponents point to Memetic Mutation as an example that Memetics isn't a viable model.
- The early stages of ants infected with Ophiocordyceps unilateralis, AKA the zombie fungus. The ant is physically unchanged, but begins exhibiting odd behaviors like seizing out of its nest, climbing up the nearest suitable plant, and chomping down on a leaf so hard that it remains fixed there permanently while the fungus grows. As the fungus progresses, however, it takes over the ant's body physically as well as mentally - as fungi tend to do with decomposing organisms.
- The lancet liver fluke is capable of controlling ants as well. Normally, ants retreat into their nest at night, but when a fluke gets in control of one, it causes the ant to climb up to the top of the nearest blade of grass and clamp its jaws down on it in hopes that the parasite's next host - a large herbivore - will mistakenly consume the ant along with the grass. However, the ant doesn't die as it does with the fungus; if it isn't consumed by an herbivore, it will instead climb down from the grass at dawn and continue to go about its daily ant activities, only to climb back up the grass at the next sunset.
- Humans infected with Toxoplasmosis, a protozoan found in cat feces, have been shown to have several oddities in their behavior (up to the point that Crazy Cat Lady might ought to be renamed Toxoplasmosis Infectee). Infectees can develop mental symptoms that resemble schizophrenia, and some, particularly men, are known to lose their aversion to the stench of cat urine such that a dirty litterbox no longer bothers them. Toxoplasmosis also has an acute disease phase which resembles more traditional ills, with fever and malaise and the like, but it's the latent phase which is this trope.
- Humans aren't the only ones who are affected by the infection. Rodents with Toxoplasmosis in their brains spend an excessive amount of time running around to draw attention to themselves and completely lose their fear of feline scents, even seeking them out. This serves to get the Toxoplasmosis into a cat, which is where it really wants to be.
- Rabies is best known for its "furious" state, in which the virus drives the host to actively and violently seek out victims to bite. This is, of course, to ensure its own transmission. The other thing it's known for is hydrophobia, an irrational fear of water (which serves no purpose other than to weaken the infectee such that they will die sooner and infect fewer new victims).
- The phenomenon termed folie à deux, or "shared psychosis/shared psychosis disorder". For those who are susceptible to madness, simply being around another unstable person can not only trigger a psychotic episode but can cause their form of madness to come to resemble the other person's, meaning that a form of mental illness normally thought of as self-limited suddenly becomes contagious.
- The Green-banded Broodsac is a parasitic flatworm that uses land snails as a intermediate host to get to their real host of birds. The broodsac accomplishes this by forming large broodsacs in the snail's tentacles (preferably the left one) filled to the brim with cercariae (free swimming larvae) to look like a fat, juicy caterpillar and reduces the snail's ability to sense the change in lighting so that it will mistakenly crawl up into a high place, thinking it's night time, and let a bird rip off the tentacle to allow the broodsacs to develop to adulthood in the bird's insides to start the cycle again.