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Voiced by: Grey DeLisle

A rogue AI based in space.

  • A.I. Is a Crapshoot: Was created by Caesar to contain any rogue Nanites, now wants to destroy the world as a result.
  • Big "NO!": First appearance in episode 5.
  • Kill 'Em All: Anything with nanites, at least.
    • Kill All Humans: Which is almost every living thing on the planet in the series.
  • Manipulative Bitch: She's very good at getting humans to do what she wants, first tricking an entire colony of people into helping her build a Doomsday Device and in her second appearence hiding out in their robot buddy until they'd done everything she needed them to do.
  • Not Quite Dead: Even if it showed up out of pretty much nowhere, this was pulled quite nicely in Gravity. Twice!
  • Omnicidal Maniac: Has absolutely no problem killing all life on Earth (well except White Knight, who is uninfected) just to protect herself.


  • Authority Equals Asskicking: His debut episode was one thing. When next he shows up, he takes on Rex and the Pack (separately) and was easily a better fighter than all of them. He's not an Evo to be taken lightly.
  • Brought Down to Normal
  • Diminishing Villain Threat: Despite those victories, in his third appearance, his skill has considerably diminished, Rex could beat him easily, and he only got a few good hits in, it might have been to show how good Rex has become as a fighter, but No-Face still put up a pitiful fight, and went down easily. In addition, when Cain said that he would kill Rex, No-Face did nothing about it, this clashes with his second appearance, where he went ballistic when Van Kleiss attempted to stop his vengeance against Rex!
  • The Faceless: Until he got cured in the finale.
  • Mission Control: Coordinates the other Evos in the Bug Jar to make them more effective.
  • Multi-Armed and Dangerous: He has four arms.
  • Sealed Evil in a Can: He's trapped inside the Bug Jar. And he wants out!
  • Villain Team-Up: Van Kleiss tries to orchestrate one with him. It fails. Happens again in "Enemies Mine", which worked better since all involved wanted Rex dead. Not that they succeeded, of course.
  • Telepathy: How he controls the other Evos.

    Hunter Cain
Voiced by: John Cena (debut), John DiMaggio

  • Bald of Evil: With a scar on the top.
  • Enemy Mine: The aptly named "Enemies Mine" has him working with other enemies of Rex. However, he turns on them at one point when it looks like he could kill Rex himself.
  • Fantastic Racism: Hates all Evos after his own wife transformed into one.
  • Hypocrite: Despite making it his goal to destroy EVOs, near the end of his debut episode, he admits that he created the ones that his men and Rex were currently fighting to discredit Rex and prove he was better. He also teams up with No-Face in a later episode, which Rex immediately calls him on. There's also his lack of regard for any non-Evo who gets in his way.
  • I Call It "Vera": His BFG, Sweet Caroline. It's presumably named after his wife who turned EVO.
  • Name of Cain: Although it's never stated how to spell it.
  • It's Personal: His grudge against Rex and all other Evos.
  • Kill 'Em All: His overall goal is to kill off all Evos.
  • Not-So-Well-Intentioned Extremist: Wants people to see him as the hero, but it's clear he's a just a man consumed by hatred and paranoia looking for an excuse to hurt others.
  • Shout-Out: He physically resembles Jason Voorhees.
  • Spell My Name with an "S": How are we supposed to spell his name, exactly? note 
  • Villain with Good Publicity: Very popular as shown in his debut episode until he's exposed for creating EVOs to gain said publicity.
  • Would Hurt a Child: Especially if that child is an EVO.

    Claire Bowman and Annie
Voiced by: Danica McKellar (Claire), Felicia Day (Annie)

A pair of "normal" teenage girls that go on double dates with Rex and Noah. They're both scientific prodigies and Annie has notoriously dangerous bad luck. So bad that Noah recruited Rex to go out with her because he didn't think anybody else could survive the experience.

  • The Jinx: Annie is also known as "the blonde widow" for this reason and has used this trait as a weapon on occasion.
  • Lethal Klutz: Every normal boy who has gone on a date with Annie has ended up in hospital. It is speculated that second date would kill them.

Voiced by: Greg Ellis

  • Affably Evil: Is surprisingly polite to his enemies even in battle.
  • Card-Carrying Villain: He is unabashedly this, and readily admits it.
  • Equal-Opportunity Evil: There are no ladies in his gang. He thinks something needs to be done about that.
  • Large Ham: Oh god, is this guy chewing the scenery... In fairness, he does seem to be aware of his hamminess, and enjoys it quite a bit, sort of like an in-universe example of Ham and Cheese...
  • Not So Different: Played straight and inverted.
    Rex: I've got the unstable nanites right here! Back off or I'll send us all to Kingdom Come!
    Gatlock: You wouldn't dare!
    Rex: Or would I? You said you and I are a lot alike...
    Gatlock: You would.
  • Pirate: Desert variant, though he wonders if the spyglass is too cliche.

    Branden Moses
Voiced by: Nolan North

A famous scientist who’s seemingly discovered a cure for all EVOs. In reality, he’s a fraud who sells his EVO patients as Super Soldiers to the highest bidder.

  • The Anti-Christ: Well, more like "The Anti-Moses", but same basic principle. Pretends to want to cure EVOs (supposedly freeing them of their condition, so to speak), but instead enslaves them. (the opposite that the the Biblical Moses wanted and tried to do, which was to free slaves).
  • Auction of Evil: Runs one where he sells incurable EVOs as Super Soldiers.
  • Bitch in Sheep's Clothing: Promises a cure, but it turns out to be a scam.
  • Faux Affably Evil: Pretends to be nice....until his true colors are revealed.
  • Ironic Name: His last name is Moses....yet he enslaves others.
  • Superhuman Trafficking: He auctions off his patients as One Man Armies to various criminals.

Voiced by: Mark Hamill

An EVO crime lord who Rex used to work for, prior to losing his memories.

  • And I Must Scream: Even shattering him apparently doesn't kill him. It does make any sort of communication rather difficult, though.
  • Detachment Combat: In his third appearance, he can use his fist like a whip. This is apparently because...
  • Literally Shattered Lives: It's all but stated outright that Van Kleiss punished him for his betrayal by breaking his body apart. His new outfit is apparently the only thing holding him together. Taken a step further when Rex hits him with his spinning giant fist, outright shattering him into chunks.
  • Taken for Granite: His mutation turned him into living stone.

Voiced by: Jack De Sena

    John Scarecrow
Voiced by: Andy Milder

An EVO who can shapeshift.

Voiced by: Michael Emerson

Alpha is the original control nanite created by Cesar but sent to an empty dimension, where he started attempting to merge with organic lifeforms in his pursuit of a stable body. Unfortunately, that universe turned out to be the Null Void. He found a host and forced a return to Rex's world, accidentally taking Ben with him and setting up the crossover.

  • A God Am I:
    AlphaOmega: Behold, organics! The beginning and the end of all things! I am AlphaOmega! This is the twilight of humanity! AlphaOmega destroys all!
  • A.I. Is a Crapshoot: Making an artifically intelligent control nanite worked just about as well as one would expect it. Cesar seems to have a poor track record with this sort of thing.
  • Big Bad: Ben 10 and Generator Rex: Heroes United
  • Big Red Devil: Other than the mechnical form he first appears in, all his forms are quite demonic in appearance, getting even moreso as he transforms into more powerful forms.
  • Evil Counterpart: To Rex's Omega Nanite.
  • Healing Factor: So long as he has nanites to spare, the bodies he creates can regenerate nearly any damage in seconds. Becomes capable of regenerating without limit once he absorbs Rex's Omega Nanite, which can create nanites.
  • Horror Hunger: Like Van Kleiss, he absorbs nanites from Evos to sustain himself. However, he reduces his victims to dust!
  • Implacable Man: No matter what you hit him with, he just keeps coming and can regenerate from nearly anything. The only way to truly stop him is to target and somehow hit the one tiny Nanite in his entire body that's actually him.
  • Machine Monotone: Constantly speaks with one.
  • Omnicidal Maniac: Once he turns into AlphaOmega.
  • One-Winged Angel: Three times. First after absorbing all the Nanites in the Bug Jar to turn into a hulking monster. He then copies the Ultimatrix, allowing him to turn into monster versions of Ben's aliens, but Rex manages to cancel that. He finally absorbs Rex's Omega Nanite to transform into the gigantic AlphaOmega.
  • Person of Mass Destruction: Is outright stated to be capable of single-handedly destroying the world.
  • Psychopathic Manchild: Is rather child-like in his mannerisms and speech, speaking to Cesar, his creator like a child seeking its parent's approval and guidence. He's also extremely dangerous and has no regard for life in any sense of the word. While he gradually gets more mature as he evolves, traits of the manchild part are still there, and he gets much more psychotic.
  • Psycho Prototype: The prototype control Nanite, and is monstrous, psychopathic entity.
  • Sealed Evil in a Can: Was supposed to be imprisoned in an empty dimension where he couldn't do any damage, but it turned out it was the Null Void and he escaped. Rex and Ben defeat him and imprison him in an extremely dense sphere, which Ben then leaves in the Null Void for good measure...But the ending implies he's going to escape anyway.
  • Super Prototype: Of the Nanites; he's not called Alpha for nothing.
  • Sentient Phlebotinum: Is a sentient nanite. Any body he creates is normally composed of a swarm of absorbed nanites as well.
  • Technopath: Like Rex, he can manipulate machines by touch. The first body he shows up in was apparently a mechnical Null Void prisoner he merged with.
  • Voice of the Legion: After going One-Winged Angel.

Voiced by: Steve Blum

  • Feel No Pain: His copies don't. Rex uses this to find the real one he needs to cure.
  • Hipster: Insists he's a real fan because he's a fan of the Trendbenders' older work. Also complains about them "selling out" all the time.
  • Loony Fan: Of the Trendbenders' older work. Eventually kidnaps them intent on making them put on a final private show and then kill them.
    • Also on the obsessive-collection end, where he has every version of their albums, including ones sole in other countries.
  • Me's a Crowd: His power is to make copies of himself. Rex originally thinks it's just three, but he can make a whole army's worth.

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