The last few panels of this strip of Erfworld could definitely be considered. Jillian's reaction to Ansom's death is understandable, but seeing a normally stoic Vinny break into tears makes it that much more powerful. Certainly no one expected to see the two of them share a hug.
The final chapter of A Miracle of Science. Two — or is it three? — likeable, slightly damaged characters who've had a budding romance throughout the story get to fly off into the sunset together. D'aw.
Shadowchild spends most of its time warming this troper's heart; it's so cheerfully enthusiastic. Every new discovery and experience is like Christmas for it. Even being told that it can be cold if it feels like it results in a gleeful "Yay!". I just wanna hug it 90% of the time. The other 10, however...
This and the two following Vinci & Arty strips - after a big fight, the titular characters forgive each other. What makes it touching beyond belief is that the only words used are the lyrics to Ben Folds' The Luckiest in a semi-narrative form.
Both are touching, but this one takes the "aww" Up to Eleven. The comic came out two weeks after Christmas due to unexpected delays, but Scott didn't want to give up on it.
The above-mentioned Christmas comic has touched the hearts of people who have given up on VG Cats after they had a Dethroning Moment of Suck episode with the comic. Well done, Scott.
This troper found this and the following strip in Sheldon to especially tug at her heart strings. After finding a to-do list that was written years ago by his dead wife, the grandpa is sitting down staring at it when he suddenly pauses, looks up and smiles. In the last panel, we see him in the yard fixing the back gate, as it was one of the things written on the list for him to do.
PvP, this strip. Anyone not touched by this has no soul.
The reunion of Zimmy and Gamma in Zimmy's nightmare world in Gunnerkrigg Court. Creator Tom Siddell's comments for the page are simply, "Here it is. The only thing Zimmy could ever give a damn about."
This strip from The 10 Doctors. Dozens of companions from different times, places, worlds... and every single one of them would give up their life for the Doctor. The Brigadier sums it up best:
The Brigadier: "All we have in common is you, Doctor. You are worth the risks. We need you. That's how you've touched the universe. We're not giving you up that easily."
The Duck's rescue of the protagonist of HERO and his friend Valentine never fails to make this troper awwww. Especially when it starts singing off-key.
ThisStriptease comic. The main character Max has been seen wearing the same shirt since the very first strip, and it is easily overlooked. The author reveals its symbolism in a flashback to an ex-girlfriend he had back in college. The best part? He does it to give his Alli, his on-and-off girlfriend and main rival in the comic industry a chance to continue her comic at the cost of his entire career.
Slightly Damned. Buwaro, a demon, deciding to use his adoptive angel father's last name even though he doesn't remember a thing about him.
Said Buwaro confessing his love to Kieri, an angel. And her response.
This page of Problem Sleuth. So touching it actually warmed the final boss's heart. This troper also finds this strangely heartwarming as well.
Kevin & Kell's moment is when the human Danielle, now changed into her rabbit counterpart in that world, is having trouble fitting in considering that she is still an omnivore that freaks out nearly everyone when she forgets to hide it. Looking for a kindred spirit, she finds young Coney, a bunny kitten who is a carnivore herself. Cradling her when the kitten is sleeping peacefully on her lap, Danielle notes "Psst, You have a human soul in there too, don't you? In that case, I'll stay."
Captain SNES: The Game Masta has a moment. Hey stop snickering! It's true! When talking about the events in Nexus, Alex's Capator has problem saying the word died. Alex goes on to mock him about it not being a curse word even if it is a four letter word. The Capator admits that it scares him...Which leads to Alex aplogizing to him. D'aaaaaaaw.
Wave of Hope. Even if it can't magically fix everything, it shows that Videoland's decay isn't irreversible, and things can be like they were again.
Red String: Eiji and Reika'sRelationship Upgrade, anyone? "So, does this mean we're not 'friends' anymore?" "Yeah. I think so." * handclasp, "I want to kiss you", the First Kiss, and a large collective squee from the fanbase*
Count Your Sheep has quite a few of them - as is to be expected from a comic about a little girl, her single-parent mother and an imaginary sheep - but this troper really loves thesetwo in particular.
The title characters of Penny and Aggie putting aside their rivalry to stop the bullying by Karen and her clique. A particularly powerful moment, as it came at the end of the comic's most gut-wrenching chapter, with both characters at their lowest ebb.
Penny: Ready to save the world, you post-ironic post-yuppie?
Also their moving from allies to genuine friends in thesestrips.
When Aggie gets in trouble with the principal for commandeering the P.A. system to announce her candidacy for student council president, she asks her father whether he's angry with her. Nick's affectionately ironic response: "Standing up to authority for principle, trying to reach the kids who think like you...Your mother and I are furious."
In Tales of the Questor, Quentyn is in the stables looking for a mount for his dragon fighting mission and has just been disillusioned almost to tears about unicorns. Suddenly a horse trader speaks up and says he has a mount that could be suitable for the famous Raccoonan knight. At that he leads them to Ember, a tiny horse that was part of a unsuccessful breeding project for mounts for Dwarves, but now was likely to be sold to some princess. However, the trader makes an offer of it to Quentyn, and the little horse affectionately nuzzles up to the Raccoonan to seal the deal.
Just read through Housepets!, and you'll probably feel more than a few tugs on the old heartstrings.
This absolutely beautiful Drowtales strip. Don't miss Naal's little "Silly" on the right, or her smile. (Link may not work after edits—it's near the end of chapter 24).
Pauline's funeral service in Our Little Adventure was very nice. It was kept fairly light-hearted and tasteful and ended with Julie's cute little parody song of "When She Loved Me" by Sarah Mclachlan as she and the adventuring group saw Pauline's ashes fly away back toward her home island.
This◊ strip of Murphy's Law which shows not only Matt's but Radic's character development also manages to be one of these.
In Dubious Company, Tiren changes allegiances to the Imperial Guard. Some later Navel-Gazing ends in this strip. The moment carries on for the next 5 or 6 pages.