You just walked in on the guy your roommate hooked up with dancing around your apartment with nothing on but a condom? Yes, the proper reaction is to put up a banner, get some party hats, and throw confetti.
Momo's new chassis. Judging by the nosebleed, Marigold is going to be eating ramen for longer than she lets on to pay it off. It establishes Momo is more than some kind of surrogate pet/comic relief character (the way Pintsize or Winslow are usually portrayed); Marigold cares for her pretty deeply.
Not only was this just in time for Christmas, but Jeph actually wrote the entire fictional speech, of which he only used an excerpt in the comic, which somehow makes it even more heartwarming. It can be found here.
Double CMoH; The AI on Hannelore's Dad's space station apologizes to someone he played a cruel prank on by giving her some shares in Ellicott-Chatham Technologies. The fact that he owns shares in the first place reminds us that AIs really are humanity's equals. The second part comes when he says the shares she now owns are worth 4.6 Million US Dollars. Her ponytail comes undone from the shock.
Hannelore's words of encouragement to Marigold. They become even more touching in retrospect as the next few strips show how much Hannelore is speaking from her own heart about having come through to the other side of that day herself.
Someday, everything is going to go right for you, and it will be so wonderful you won't even know what to do.
And in a meta-example, the fan response to it and Jeph's reaction to it, especially considering it occurred about a week after he'd had a Creator Breakdown due to Fan Dumb.
Jeph's Twitter: I wish I could share some of the emails I'm getting about Claire with you guys. They are amazing.
And later, after getting an email about how QC has an "agenda" now,
Jeph's Twitter: Also got literally 1500+ emails expressing happiness about recent QC events so I guess PROJECT AGENDA is working.
Pintsize tells Momo that he was Marten's only friend for two years before he met Steve and Faye, and that he's happy that Marten has friends and a life now. He even tells Momo that there are different ways for them to do their jobs. Of course, he won't tell Marten that, as he defaults to his normal behavior when Marten asks what's up.
What started as a throwaway gag earlier on in the story evolved into a rather touching moment. Marten's dads' (yes, plural) wedding arc culminated in Martin's Mom delivering a rather heartwarming speech during the dinner showing that there is no love lost between them.
Blogpost for comic 2510: Jeph links to his first kickstarter for a Deathmøle album with a goal for $9,500 in one month. Blogpost for comic 2511: goal has already made its goal and then some: 38,911
Jeph's: Holy CRAP you guys, the response to the Deathmøle Kickstarter has been WAY bigger than I had ever dared hope! We're over 300% funded 24 hours in, which is AMAZING. Thank you so much! But it is not over yet! We are hammering out some extremely cool stretch goals and should be posting them in the next day or two, so keep your eyes peeled. Thank you, again, for your support. I am tremendously thankful.