Critora is set in the digital city of Critopia, inhabited by virtual creatures called Critora. Critopia is under a takeover threat by the Viruses, led by Queen Virus, who also want to infect the Critora to heed to their demands.
Critora provides the following:
- Animate Inanimate Object: A few Critora, most notably the major characters Coneboy Golliday and Eggy.
- Early-Bird Cameo: Despite appearing in the opening sequence, which was appendexed to the first two episodes days after "The Trash Can" premiered, the Bitzes debuted in the third episode, "Save! Delete! Copy!".
- Funny Animal: Most Critora are basically either anthropomorphic or bipedal animals.
- Shout-Out: A few of Coneboy's accessories in "The Trash Can" reference Littlest Pet Shop, Angry Birds, Peanuts, Pokémon and Wonder Pets!.
- Spin-Off: Of a little-known web comic named Avey and, of all things, Spangler's Mixels fan characters.