Oh, No... Not Again!

Strictly speaking this is supposed to be dramatic, but you know...

Red: We've got a complaint, sir. A guest found a pan-dimensional hellhound in their soup!
Monkey: Again?

A simple comedy dialogue trick is to have something bizarre happen, and then have someone say "not again", implying it's happened before. The actual phrasing can vary. A slightly less funny version (unless done just right) is where it actually has happened before, on-screen, and the character is just pointing that out.

A variation is to have the character say something along the lines of "This is just like X all over again," where X is something typically ordinary, such as prom, or graduation.

See also Here We Go Again, and This Is Gonna Suck, which can be combined with it. Is often used in conjunction with the Noodle Incident (especially if what happened the last time hasn't been mentioned or seen before, particularly if the "This is just like X all over again" variation is used). Contrast with Here We Go Again, which is used to end a story with a repeating motif.

Related to Didn't We Use This Joke Already?


    open/close all folders 

  • Jared's second Dave/GPS commercial; naturally, Dave invokes this trope as he remembers what happened last time.
  • In the second video in Game Fly's "Bad Game" commercial, a man who looks like Owen Wilson says "Not again..."
  • The head guard in a Captain Morgan rum commercial manages a nonverbal version of this, shaking his head and glaring with a look that's all too clear when he sees Captain Morgan breaking someone out of prison.
  • A kid sister yelling "Mom, he's done it again!" was the punchline to two ads from the 1990s:
    • A famous Super Bowl spot for Pepsi about a boy on a beach who quickly finishes off a bottle of the cola with a straw, then can't stop sucking for one more drop until the ensuing vacuum causes his entire body to crumple up and squeeze through the neck of the bottle so he's left trapped inside, much to the disgust of his onlookers.
    • An Airheads commercial wherein a boy's gobbling down a whole piece of the taffy turns him into its balloon mascot and rockets him through the roof. In this one the girl first warns him of what happened last time, as is evidenced by the other boarded-over holes in the ceiling.

    Anime & Manga 
  • In the beginning of Chrono Crusade, Rosette wails, "Why does this sort of thing always happen to me?!" after her mission to exorcise a demon ends in her crashing a ship into the Statue of Liberty. The very next chapter confirms that this sort of disaster happens because of her all the time.
  • Early in Cyborg 009 when the cyborgs were painting their ship, 007 accidentally knocks down a bucket of paint on 008's head while arguing with 006. A noisy chase ensues, which 004 comments laconically:
    004: Not again.
  • Dragon Ball Z
    • During the Buu Saga, after Piccolo and Gotenks discover the ruins of the Lookout, Piccolo states "the Lookout is destroyed... again." Those who've watched the Anime will most likely think back to the Garlic Jr. Saga, which is the only other time that the Lookout was destroyed (onscreen, anyway).
    • Similarly, when Krillin, when trying to come up with an excuse for Gohan's whereabouts to Chi-Chi, considered saying "Gohan's been kidnapped again!" The only other onscreen times he was kidnapped was during the events of the film Dead Zone, and when Raditz kidnapped him at the start of DBZ.
  • Boss from Mazinger Z has his made-of-scraps-and-junk Humongous Mecha (Boss Borot) wrecked nearly each episode, so often he utters one sentence along the lines of "Why it is always me?", or "Not again!". He even lampshades it in one UFO Robo Grendizer manga chapter: He is going to fight Great Mazinger (long story), and he is knocked down with a mere backhand. Then he says "The most painful thing is I knew what this would happen."
  • In the Great Mazinger vs Getter Robo features, Boss Borot's arms gets eaten by a Robeast. Later his Humongous Mecha gets rebuilt, he fights that Robeast again... And his robot's limb gets eaten again. Boss yells: "What? AGAIN?"
  • One episode of Code Geass had Kallen compare their current situation to "what happened in Aomori"; C.C. responds that "at least this time we have our clothes".
  • In One Piece, Franky's speedo is stolen and he goes on a rampage throughout Water 7 trying to get it back. Then this exchange occurs:
    Random Villager 1: There's a pervert! Franky's running wild and pantless!
    Random Villager 2: Again?!?

    Comic Books 
  • Silver Age Superman once flew through Hell, causing Hitler to look up and shout "Oh no, not again!" Golden Age Superman had defeated Hitler in one of Action Comics's first issues.
  • Negation had the Catch Phrase BOHICA (Bend Over — Here It Comes Again).
  • Batman:
    • The image at Joker Immunity is from The Batman Adventures comic Mad Love. It has the last two words of this trope. (The panel before showed Batman hitting the Joker out of a train and him saying: "Oh, no...")
    • The Trope Image comes from Batman issue 246 where a villain kidnaps Robin and then keeps "killing" dummies of him in various ways all over the place.
  • Transmetropolitan: A particularly deranged-looking Spider hails/hijacks a cab.
    Cabbie: Please don't kill me and eat me! I couldn't bear to be killed and eaten again!
  • The Don Rosa Duck comic, The Quest for Kalevala, the sea-monster Iku-Turso wreaks havoc on Helsinki. An citizen calmly comments:
    "Wow, that is the second biggest frog I have ever seen."
    • Amusingly, it actually is a subtle Shout-Out to Don Rosa's old comic series, The Adventures of Captain Kentucky.

    Comic Strips 
  • In an early FoxTrot arc, Andy becomes quite paranoid that her husband Roger is having an affair, when he calls to tell her he'll be home late again. As Andy continues to think of ways he could be lying to her about what he's really doing, Roger counters her questions with substantive answers. He even puts the phone up to his desk chair and says "Listen — you know how my chair squeaks?" "Sounds like bedsprings", Andy replies, and Roger yells for a coworker named Fred to "get over here and talk to [his] wife", to which the coworker groans "Not again..."
  • The Far Side:
    • A hippie stops at a house to ask for directions; upon noticing that the person he's speaking with is an elephant-bird-giraffe-man, the hippie says, "Oh, wow, déjà vu."
    • In another one, a group of soldiers at a frontier fort are being attacked by assailants using suction-tipped arrows. One of them groans, "Cripes, not these Indians again!"
    • A duck and a scientist both wash up on a deserted island. The duck says, "So, Professor Jenkins!... My old nemesis!... We meet again, but this time, the advantage is mine!"
  • Garfield:
    • Garfield is complaining about how there's only reruns on TV, and leftovers in the fridge. Then Jon runs by, screaming about how the plumbing has backed up, and pirahnas are spawning in the toilet. Garfield's reaction? "Again?!"
    • In one strip around Christmas, Garfield comments that it still doesn't feel like Christmas — and then Jon comes in tangled up in Christmas lights with the tree strapped to his back:
      Jon: I did it again.
      Garfield: NOW I feel Christmasy.
    • In a 1991 strip, Garfield reflects that life with Jon is not normal. Jon walks past announcing his intention to tap dance on the front lawn in his underwear with a balloon animal tied to his head and carrying a pineapple in each hand, and dressed and equipped for exactly that. Garfield, his expression unchanging, simply thinks, "Again?"
    • In a strip popular with Square Root of Minus Garfield contributors, Jon has glued a blender to his face. Garfield is stunned: it's Saturday already? Evidently, this is a weekly thing for Jon.

    Fan Works 
  • In A Very Potter Musical, when Voldemort and Malfoy are making an Unbreakable Vow (i.e. a spit-shake):
    Malfoy: (before Voldemort can get out of the shake) And you have to be my slave for a whole day starting now!
    Voldemort: You little shit! You got me, oh this is so embarrassing! That's the second time that's happened!
  • In the Potter Puppet Pals episode "The Vortex", we have this exchange:
    Hermione: Professor Dumbledore! Ron's trapped in an alternate dimension!
    Dumbledore: Oh no, not again!
  • Yet more Harry Potter silliness: Oh God Not Again is a breezy Peggy Sue-parody fic in which 23-year-old Harry gets to relive his entire childhood fortuitously having done it all before.
  • In Origins, a Mass Effect/Star Wars/Borderlands/Halo Massive Multiplayer Crossover, the trope appears as a chapter title and is promptly lampshaded by Samantha Shepard—mainly that the Big Bad they thought might possibly be defeated in fact, was not. The Flood is pretty hard to kill.
  • Used to lampshade the increasingly frequent instances of "darkness enfolding him" in Toy Hammer.
    "Darkness enfolded me. Again."
  • Said by Fakir in Princess Tutu Abridged: "Did I just get taken out by a ninety pound ballerina? Damn, not again."
  • Takamachi Nanoha Of 2814 has a spectacular example that is entirely in line with canon.
    "I am going to die a virgin," Tuxedo Kamen said, then added conscientiously, "Again."
  • Negi Springfield in Equal And Opposite Attraction quotes this verbatim before passing out when he discovers that, yet again, he is teaching mages in his class.
  • Sasaki says this almost word for word (she drops the "no") in chapter 54 of Kyon Big Damn Hero. It's the third time she's been captured by the Sumiyoshi-rengo.
  • Said by Sam in Strength In Numbers when she learns that Danny had a two-hour eating binge again.
  • Second Wind: Zoro gets this reaction in Chapter 3 when, after meeting Luffy in Shells Town, he discovers that his captain has no ship with which they can set sail. He reflects that some things never change in regards to his captain's tendencies as an Idiot Hero.
  • This is Apollo's reaction in Turnabout Substitution when Phoenix Rick Rolls him over the phone.
  • From Monster of the Week's take on The X-Files episode "Demons"
    Mulder: (over the phone) Hey, Scully. I just woke up covered in blood in Rhode Island.
    Scully: Again?
  • Ultra Fast Pony. In "Hippocratic Oafs", Twilight's only reason for saving Ponyville from the giant bear is, "So, Celestia says she doesn't want to lose another entire town to bear attacks this week, so consider yourselves lucky!" In "One Joke to Rule Them All", Rainbow Dash's pet parasprites turn violent, and her reaction is, "My new family's trying to kill me again!"
  • In the Super Therapy! session "Aquaman Therapy!", Aquaman says it after his latest date, which he brought under the sea to discover the beauty of it, unfortunately drown while he's busy talking to fishes. Again.
  • Xander's reaction in Sounds Fishy to Me or Blackened White Fish to being chained up in a dungeon is a simple "Not again." And again when he learns the villain plans to experiment on him.
  • In I Against I, Me Against You, this is Church's reaction upon returning to the rvb world and realizing that everyone is separated just like at the end of Season 2

    Films — Animation 
  • From The Adventures of Tintin:
    Tintin: Mrs. Finch! A man's been shot on our doorstep!
    Mrs. Finch: Not again.
  • Little Nemo: Adventures in Slumberland:
    • During the song about training Nemo to be a prince, the horse that Nemo tries riding on flips him off his seat and onto the fat dancing lady, who catches him, and he says, "Not again!", indicating that she has tried to make him dance before.
    • Earlier in the film, when Nemo is first supposed to meet the king, he finds the throne to be empty, causing Professor Genius to say this exact phrase.
  • The Running Gag in Rockin' with Judy Jetson where Felonia Funk goes into a bounce-off-the-walls rage if she even hears the word "music," forcing her lieutenant Gruff to douse her with water. The first time it occurs in the movie, he grumbles, "Here we go again."
  • At the beginning of Astérix Conquers America, this is the Roman senate's reaction to learning that another platoon of legionaries has gotten thumped by Asterix's village again.
  • In Lilo & Stitch, Nani runs into her love interest David after a fire-dance gone wrong leaves him slightly singed.
    Nani: Did you catch fire again?
    David: Nah, just the stage.
  • Said word-for-word by Lord Farquaad in Shrek 4D when he's faced against Dragon again.

    Films — Live-Action 
  • Used twice in MouseHunt. First, when the Mayor faints after swallowing half a cockroach, his wife yelps, "Oh, no! Not again!" Later, when Lars and Ernie go to the animal shelter and ask for a vicious cat, Mory tells them he has the perfect one: "I had all but given up hope of anyone wanting him. We were about to gas him again."
  • John Hurt's character gets out this line during his cameo in Spaceballs when a miniature Alien bursts out of his chest — which is, of course, an Actor Allusion to his role in Alien.
  • Star Wars:
    • Along similar lines, in Attack of the Clones when Anakin dives off the side of a speeder in the middle of high-speed, flying traffic, all Obi-Wan can come up with is, "I hate it when he does that."
    • Later in the same film, Anakin's lightsaber is destroyed (leaving him weaponless). When he realizes it, he laments "Again? Obi-Wan's gonna kill me."
  • In Mary Poppins, about fifty chimney sweepers roll out of the Banks family's fireplace and start dancing around singing. And the first thing the cook says when she sees them is, "They're at it again!"
  • After a hotel-roof shootout in Last Action Hero, culminating in a crane causing a helicopter to crash, Jack Slater (portrayed by Ah-nold) asks his kid sidekick to bring the car around. Upon being informed that the helicopter landed on it, he replies, "I hate it when that happens."
  • Die Hard 2: "How can the same shit happen to the same guy twice?"
  • In Beerfest, Jay Chandrasekhar's character wakes up naked in the middle of a field after a night of heavy drinking. Lying next to him is a dead deer with blood around its neck, Jay's character with blood all over his mouth. "Ohhh, not again!"
  • Rick O'Connell in The Mummy Returns upon seeing the Soldier Mummies back in action. "Oh no, not these guys again!"
  • In Scott Pilgrim vs. The World, Scott's sister Stacey finds out Wallace has seduced her new boyfriend behind her back. Her response? "Wallace? AGAIN?!"
  • In Airplane II: The Sequel: "Ted, I have the strangest feeling we've been through this exact same thing before."
  • At the very end of the Doctor Who television movie the Doctor is just settling down to relax in his TARDIS when his gramophone starts to skip, causing it to repeat the word "time" over and over again, just like it did at the start of the movie. The last line is the Doctor's despairing "Oh no... not again!"
  • The "This is just like X all over again" variation occurs in The Avengers (2012). Black Widow comments that the fight they're currently in is "Budapest all over again." Hawkeye snarks, "You and I remember Budapest very differently."
  • Jay and Silent Bob Strike Back:
    • The studio guard interrupts the filming of the Show Within a Show Good Will Hunting 2: Hunting Season with the announcement that they have "a 10-07 on their hands." A 10-07 (two unauthorized persons on the studio lot) is not to be confused with a 10-82 (disappearing a dead hooker from Ben Affleck's trailer). But the guard's announcement does cause the following exchange:
      Matt Damon: (exasperated) Oh Jesus! Again Ben?
      Ben Affleck: (cocky) No, bullshit! Because I wasn't with a hooker today, ha-HA!
    • Later in the same movie, Mark Hamill has this trope as his response when his hand gets chopped off.
  • In Sherlock Holmes, Mrs. Hudson spots her tenants' dog keeled over on the floor. Watson's follow-up response implies this is a somewhat regular occurrence.
    Mrs. Hudson: Oh, look, he's killed the dog. Again.
    Watson: (to Holmes) What have you done to Gladstone now?
  • In the soundtrack to John Carter, the music that plays when John is fighting the White Apes is called "The Second Biggest Apes I've Seen This Month". Considering that the White Apes are about 5 metres tall...
  • In the German movie Fack Ju Goethe (English title: Suck me Shakespeer), this happens after the teacher Mrs. Leimbach-Knorr jumps out of a window. "Oh, Mrs. Leimbach-Knorr. Not again!"

  • The Hitchhiker's Guide to the Galaxy, where two missiles in flight are turned into a whale and a bowl of petunias. The whale has an entire internal monologue, but the bowl of petunias just thinks "Oh no, not again." One of the sequels actually explains why it thinks this, turning it into a Brick Joke.
  • Discworld:
    • A subtle example: It's demonstrated in Carpe Jugulum that in the kingdom of Lancre, a child's legal name is whatever the priest calls them at christening. One of the characters later mentions a former king named "My God He's Heavy the First". That may not be an example, as it tradition to give monarchs a number based on their name when they are crowned, even if there has never been another monarch of that country with that name before. Of course, this being Discworld it's rather more likely than in our own world that there actually was a King My God He's Heavy II.
    • One of the "flashbacks" in Thud! reads "On this day in 1802, the painter Methodia Rascal woke up in the night because the sounds of warfare were coming from a drawer in his bedside table. Again."
    • In Jingo, Vetinari says to Colon, "Oh, no, this is going to be like that business in Djelibeybi all over again, isn't it?" They were never actually in Djelibeybi together; he just says this, and Colon plays along, to get the attention of the crowd and let Vetinari steal a flying carpet.
  • In Lev Grossman's The Magician's Land, a Pegasus says this exact line when hearing that the land of Fillory is dying.

    Live-Action TV 
  • The Office: "He's put my stapler in the jelly again!"
  • Stargate Atlantis:
    • When Dr. Weir's mind is taken over by an alien, everyone reacts with shock. Except McKay, who just whines, "not again". We'd seen another character taken over by aliens a few episodes before. Before that, McKay himself had had a woman's mind inhabit his brain and take over his body.
    • McKay also says this when he's trapped in a sinking ship for the second time.
  • In Buffy the Vampire Slayer, a warning of the impending apocalypse is met with a Collective Groan of "Again?" by the Scoobies. We've seen several near-apocalypses before.
  • 30 Rock:
    • In an episode, Liz, trying to figure out why a hot man wants to date her, tells him at one point that "If you're a gay guy looking for a beard, I don't do that anymore!"
    • In another episode, she asks Jenna, "What's going on? Why are being so happy and nice? Are you soaking your tampons in vodka again?"
  • Get Smart:
    • A more specific version is one of the best-known running gags from Maxwell Smart.
      Max: The old Professor-Peter-Peckinpah-all-purpose-anti-personnel-Peckinpah-pocket-pistol-under-the-toupee trick. That's the second time I've fallen for it this month.
    • He also notes that some absurdly large items are "the second biggest __ I've ever seen."
  • Smallville:
    Chloe: Clark has amnesia.
    Lois: Again?
  • One episode of NCIS had a suspect, upon walking into his living room to find the team pointing guns at him, say "Not this again! Bloody hell!" Interestingly enough, he also was rather surprised to find they're cops.
  • Queen Machina in Power Rangers Zeo when Mondo is struck down by the Super Zeo Megazord.
  • Tenaya on Power Rangers RPM, the second time Dr. K grabs her violin.
  • The Mad TV sketch "Gump Fiction" had Phil LaMarr reprise his role from Pulp Fiction. As a nod to the meta, he shouted out, "Not again!".
  • On Press Your Luck, one of the Whammy animations featured one attempting to blow up the contestant's winnings with a Plunger Detonator, only to have it blow up in his face instead; this is followed by "Not again..."
  • On The Big Bang Theory, when Sheldon sees Leonard and Penny kissing after they've broken up, he sighs "Oh, friggity-frack, not this again."
  • Played with on Parks and Recreation:
    Leslie: Some guy handcuffed himself to a pipe in my office because we wouldn't put a copy of Twilight in the time capsule.
    Ben: (sarcastic) Dammit, again?
  • A Sabrina the Teenage Witch episode had her aunts warning Sabrina about wish magic in which if a witch desires something or someone enough that their magic can make them spontaneously appear. The aunts demonstrate this by saying the name of singer Randy Travis three times and he promptly appears in their kitchen. Travis looks around and instead of freaking out he sighs and says, "Hello Hilda, hello Zelda and you must be Sabrina. I've heard a lot about you." Reinforced when he leaves the house: "If you need me, you know where to find me... you always do."
  • In a late season 6 episode, How I Met Your Mother went meta when Ted responded to something Barney said with him having the feeling that in fact, they collectively learn the opposite lesson at least once every year for a while now.
  • Neds Declassified School Survival Guide: In the Guide to Money, one of Cookie's several failed attempts involves a failed ventriloquism act. Moze sees the poster, and she invokes this trope.
    Moze: Oh, no. Not Baxter Bear!
  • Doctor Who:
    • The trope appears in the episode "The Rebel Flesh":
      The Doctor: I have to get to that cockerel before all hell breaks loose! (beat) I never thought I'd get to say that again.
    • And this gem, from "Night Terrors":
      Rory: Oh great, we're dead. Again.
    • In the end, Amy died twice and Rory died ten times (and only three times off-screen). Rory deserves particular mention for dying of old age twice without use of any rapid-aging phlebotinum.
  • When Leverage's Eliot uncharacteristically starts making Sophie tea, Parker asks her if she's hypnotized Eliot "again".
  • Two separate occasions with Joy in My Name Is Earl:
    Joy: Darnell, get me a rag! Somebody kicked me in the face in the bathroom again!

    Joy: Darnell, call the police! Exterminator sprayed me in the face with rat poison again!
  • This brief exchange in House, reinforcing the title character's "everybody lies" belief.
    Random Patient: I'm still a virgin.
    House: (flatly) You're pregnant.
    Patient (exasperatedly resigned) Again?
  • Scrubs as the exact same scene as part of a montage that eventually breaks Turk. It's played for laughs. Kinda.
  • Hilariously used by George Takei in Psych. Throughout the episode, there are references to a horrible experience he had at a convention in San Antonio. Shawn and Gus (who have tricked Takei into thinking they're assistants he doesn't remember hiring) end up solving their case on stage just as Takei is about to go on, with Shawn pretending to use Gus' "magic head" to channel his psychic abilities. Off to the side, Takei angrily remarks that this is the same thing that happened in San Antonio.
  • In an episode of Father Ted, Ted is showing Bishop Brennan a number of security measures to stop Father Jack from sleepwalking, one of which is a rope snare:
    Ted: I'd like to see him chew through that. (Bishop moves out of earshot) Again.
  • A Running Gag on The Cosby Show involving Sondra and Elvin's tumultuous relationship before they ultimately got married.
    Huxtable #1: Sondra broke up with Elvin.
    Huxtable #2: Again??
  • One episode of the docudrama series Untold Stories Of The ER recounted an incident in which a heart attack patient had his bypass surgery delayed because they found a homemade sex toy in his rectum and decided it was not safe to operate until it was removed. When his wife found out, the emergency physician was surprised that her response was this trope. "I told you those things are dangerous!"
  • Occurred on Saturday Night Live during Colin Quinn's stint as anchor for Weekend Update.
    Colin: Ol' Dirty Bastard was arrested again... you know, we should really keep that cue card!

  • From David Lang's "Are You Experienced? I. On Being Hit on the Head": "What happened? That felt like... a blow to my head! That's twice this week!"
  • Linkin Park lampshades this trope in "Bleed it Out" - a song about the frustration of writing lyrics:
    Now here we go for the hundredth time...

    Pro Wrestling 
  • At wXw Back To The Roots 3: When Punk Met Hero...In Germany, this was the former's reaction in a nutshell.

    Puppet Shows 
  • In The Great Muppet Caper when Beauregard drives his cab into the Happiness Hotel and then into the kitchen note :
    Pops: Well, it looks like steering wheel soufflé for dinner.
    Janice: Again?
  • From Dinosaurs, when Robby is sent home with a letter from his teacher.
    Fran: "Dear Mr. and Mrs. Sinclair, your son Robert was expelled from school today for rejecting all known belief and threatening to obliterate the foundations of social order!"
    Earl: AGAIN!? What is it with you?

  • Finishing Martian Attack in Attack from Mars and starting it again gives you this soundbite from the Martians:
    "Not you again? OHHHHH!"

  • In the Sherlock Holmes novel The Sign of Four, Holmes has been forgoing sleep out of frustration with the case, and Mrs. Hudson remarks to Watson, "I hope he's not going to be ill, sir." The radio adaptation with Clive Merrison changed this line to "I hope he's not going to be ill again," highlighting Holmes's habitual self-neglect.

    Video Games 
  • In Halo 3, if you stick a Grunt with a plasma grenade with the "I Would Have Been Your Daddy" Skull turned on, you will occasionally hear them utter "Not again!" before they explode.
  • Baldur's Gate 2 has a moment like this has a moment that is somewhere between Heartwarming Moment and Narm; if you pursue a romance with (widowed) Jaheira you will at one point be ambushed by bandits, and you have the option of taking an arrow for her... which causes the somewhat narmy reaction of "Blast you filthy bogslimes! Not again!"
  • In the WarioWare series, Ashley's theme song includes the lyrics "Pantalones giganticus! / Oh no, not again!" to conclude a presumed spellcasting attempt by the young witch. What actually happened is left as an exercise to the audience.
  • At the beginning of the Team Fortress 2 video "Meet the Spy", the huge wall-o'-signs that light up in combinations to form messages like "ALERT" — "RED SPY" — "IN THE BASE" has one that just says "AGAIN", meant to be used at the end of any message. (This board was later turned into an actual in-game prop in the map Double Cross.)
  • The boat captain from God of War, every time Kratos pwns him.
  • Super Mario Bros.:
  • Monkey Island:
    • Guybrush Threepwood has a tendency to say "that's the second-[superlative] [noun] I've ever seen!" Played with in Escape from Monkey Island, where Guybrush observes a giant sea shell and says "That's the second-biggest... no, wait, that is the biggest conch shell I've ever seen!"
    • In Tales of Monkey Island Chapter 5: Rise of the Pirate God, Guybrush will say, "Not again," and get dispossessed if he keeps trying to escape from jail using the secret passageway without the Spirit Gum.
    • Also, during the Battle in the Rain in Chapter 1, when Guybrush botches up the recipe for the Cutlass of Kaflu due to LeChuck's meddling by breaking the bottle of root beer, Elaine sighs and says, "And now we're going to die. Again. Heh. Wonderful."
  • One of the quotes that a Gruntz may say when it dies.
  • In Ultimate Marvel vs. Capcom 3, if Frank West wins a match, zombies will show up and chase him down. Sometimes, he'll angrily complain, "Again? Why do you guys always go for me?"
  • In King's Quest VI: Heir Today, Gone Tomorrow, Alexander says "Not again!" when he gets caught by the druids on his second trip to the Isle of the Mists. This "Not again!" quote marks the second time that he's been captured (the first time was by the Winged Ones).
  • Raiden's incredibly deadpan reaction to losing another arm in Metal Gear Rising: Revengeance is a simple "Shit. Not again."
  • Malvolio Portius of WildStar has a great distaste for the Chua. The "Dirty Little Secrets" video shows why.
    Chua: (puts bomb on Malvolio's goblet)
    Malvolio: (brings goblet back to his face, sees bomb) Oh, not again...
  • Final Fantasy XIII has one funny case. Early in the game, Hope finds a Pulse Dreadnought mech that can be piloted, and uses it in the Vile Peaks to allow Lightning and him to quickly bust through some enemies and barriers. Flash Forward to Chapter 11, while the party is exploring a mine on Gran Pulse, and have to come up with a way to hitch a ride on the Fal'Cie Atomos. Hope, once again manages to find another pilotable Dreadnought mech, and struggles to control it just like before, with the plan to use it to stop Atomos, leading to an exasperated Lightning to note "It's the Vile Peaks all over again".
  • During a section of Saints Row IV that parodies Metal Gear Solid, one of the guards you kill will shout "not again!" Considering it's a simulation, it's quite possible that the guard had been killed before.
  • In Crash Bandicoot 2: Cortex Strikes Back, when N. Gin's mech is destroyed he gets sucked into the vacuum of space, then when it happens again in Crash Bandicoot 3: Warped he yells "Not again!"
  • In Crash Nitro Kart, Cortex will sometimes say this verbatim when he falls off the track.
  • In Psychonauts, Becky exclaims this after an actress is crushed to death by a falling stage light, as The Phantom has struck.

    Web Animation 
  • In Sitcom #391 by ryoshenron:
    Bobby: I just stole the neighbor lady's laundry off of her clothes line, so we can frolick around in my house in her panties... again.
    Tommy: That sounds like a smashing idea, Bobby.
  • Homestar Runner:
    • In the Strong Bad Email "funny", Strong Bad tries to answer an e-mail in "the funniest way ever", and at one point starts doing a crazy dance in front of Strong Sad. Strong Sad asks his brother "Did you take some of my pills again?"
    • In one of the "Biz Cas Fri" shorts, Strong Bad's office computer explodes, reducing it to ashes. Strong Bad declares it the worst computer explosion he's ever seen. One of his computers had, in fact, exploded before then. Twice.
    • In "I Killed Pom Pom!", Homestar tries to pin the "murder" of Pom Pom on Marzipan, to which Marzi reacts with a deadpan "This again?"

    Web Comics 

    Web Original 

    Western Animation 
  • The Simpsons:
    • Barney Gumble often says this. Once after mistaking a life-sized, woman-shaped bottle of maple syrup for a woman, knocking "her" over and flooding the store.
    • Another time, after drinking an "all-syrup Squishee" and waking up in a Greek cargo ship wearing a sailor's outfit.
    • In another episode, Homer organizes half the population of Springfield into forming the world's largest human pyramid. However, thanks to human stupidity, the pyramid collapses and instead turns into a giant ball of people that rolls down the streets of Springfield. As he runs for his life from the ball, Hans Moleman cries out, "Not again!"
    • When virtually all of Springfield has joined the Movementarians, Rev. Lovejoy is seen spreading gasoline on the church floor.
      Rev. Lovejoy: I never thought I'd have to do this again.
    • "Can't we have one meeting that doesn't end with us digging up a corpse?"
    • "Can't we just call in David Bowie?" — He's already done so much for this church.
    • "Now, now dear. It's only until we have to pay off your father's desecration of a priceless artifact. (despondent sigh) I never thought I'd have to say that again."
  • The Venture Bros.:
    • In the first episode, "Dia Los Dangerous", Doctor Venture wakes up in a bathtub full of ice, with a missing kidney, and says, "Not again," then realizes this means he's missing both kidneys, causing him to calmly say, "This is serious."
    • Another when Brock realizes the boys have been kidnapped right before a bomb goes off in his face.
      Brock: (with an Oh Crap! expression) Myra's back.
  • In a reference to one of the original shorts that inspired South Park:
    Stan: Put the hat on the snowman, Tweek.
    Tweek: But what if it comes to life and tries to kill us?!
    Stan: C'mon, when has that EVER happened, except for that one time?
  • SpongeBob SquarePants:
    • In an early episode, Mr. Krabs' arms pop off while attempting to pull a dime out from a drain. Spongebob says the stock phrase exactly, implying that Mr. Krabs loses his arms on a regular basis. Even within the same episode Mr. Krabs lost his arms again, and it became a running gag that in a state of shock, disapproval or other emotional duress, he sometimes literally falls apart. There's also the repeated occurrence of Squidward accidentally swallowing his clarinet, but Spongebob only references it in a later episode when it grows from a simple gag to a plot-guiding calamity- he pulls the clarinet out of Squidward's throat, but its reed breaks off and remains stuck, requiring medical attention from Sandy to remove it.
    • Mrs. Puff says this after briefly considering changing her name and moving to another town after giving Spongebob a boating license before he's qualified to drive.
    • When he and Squidward think SpongeBob ate a bomb disguised as a pie, Mr. Krabs said he's seen this before. When questioned on it, he simply replies he'd seen it 11 times. Then Squidward, in guilt, calls the doctor for help, the doctor apparently tells him the exact same thing as Mr. Krabs.
  • Code Monkeys: "Goddamn it, that's the second time I've eaten shit this week!"
  • In The Grim Adventures of Billy & Mandy Christmas Special, the mall they visit for Christmas is ultimately burned to the ground (Billy's fault), causing Grim to wonder why every time he takes them to the mall it burns to the ground. Billy blames the economy.
  • From The Critic: "Oh good heavens!! Can't one single dinner go by without our having to discuss your rotting corpse?!"
    • And another time, when Franklin disrupts a party he's been invited to by turning himself into The Mask: "Oh dear, this is exactly what he did at Nixon's funeral!"
  • The classic bumpers from Rocky and Bullwinkle:
    Rocky: And now...
    Bullwinkle: Hey, Rocky! Watch me pull a rabbit out of my hat!
    Rocky: Again?!
  • Phineas and Ferb The Movie: Across the 2nd Dimension:
    Dr. Doofenshmirtz: If I had a nickel for every time I was doomed by a puppet, I'd have two nickels. Which, well, it isn't a lot, but it's weird that it happened twice, right?
  • Rugrats: When Charlotte arrives at the office late, her relieved assistant Jonathan says, "I thought you'd been abducted by eco-terrorists again."
  • My Little Pony: Friendship Is Magic:
    • In the episode "The Cutie Mark Chronicles", the Cutie Mark Crusaders' attempt to earn their Cutie Marks via zipline fails and ends with them covered in tree sap and pine needles. Frustrated, Scootaloo gives the following statement:
      Scootaloo: It's no use. No matter what we try, we always end up without our Cutie Marks... and surprisingly often, covered in tree sap.
    • In the episode "A Friend in Deed", Pinkie says she accidentally put the confetti in the oven and the cake in the confetti cannon... again!
    • By "Slice of Life", the citizens of Ponyville are so used to monster attacks that when a Bugbear appears, this trope is their reaction.
  • In an episode of Wildfire, the title horse agrees to be a wage in an effort to rescue a friend of his. To win, the heroes have to find out where a certain troll lives and what his name is. After they find the troll, he says they'd need six clues. Based on their experience trying to find the troll, Sara deduces his name and won. She then returns to the mortal realm, where her Native-American friend, Helen, learns her dream name but isn't allowed to tell anyone. Sara then asks for a clue and Helen says she'd need six. Sara then invokes the trope.
  • Wakfu, season 2 episode 4:
    Evangelyne: Amalia and Ruel have gotten themselves turned into ghouls!
    Sadlygrove: Again? Ruel will end up getting a taste for it...
  • Sam & Max: Freelance Police:
    Max: Curses. Foiled by a clip on tie. It's Prom Night all over again.
  • From Animaniacs when the Warners meet Sherlock Holmes and need to borrow Watson for a scavenger hunt:
    Yakko: This always happens. Every time we get our hands on a fat chubby sidekick, whammo, he's kidnapped by a Scottish guy with a huge sombrero in a flying contraption!
  • Happens to Shendu in the Jackie Chan Adventures episode: "Re-Enter the Dragon" when Uncle, Tohru, Captain Black and all of Section 13 used the same spell that Lo Pei originally used to turn Shendu back to stone and to sever him from his talisman power. Even attempting to disrupt the spell was met with failure.
  • A variation, from Archer:
    Cyril: I'm so sorry I slammed you in the gut. Geez, that's how Houdini died!
    Pam: Houdini died of AIDS!
    Cyril: No! Why do you always say that?
  • The classic Looney Tunes cartoon Rabbit Seasoning:
    Daffy: (to Elmer) You're a hunter, right?
    Elmer: Wight.
    Daffy: And this is rabbit season, right?
    Elmer: Wight.
    Bugs: (points to Daffy) And if he was a rabbit, what would you do?
    Daffy: Yeah, you're so smart! If I was a rabbit, what would you do??
    Elmer: Well, I'd... (aims at Daffy)
    Daffy: (weakly) Not again... (gets blasted)
  • Said word-by-word by Caillou's father when Caillou climbs out of the bathtub again.
  • In The Weekenders, Tino suggests that an unresponsive Carver's brain will leak out of his ears unless someone plugs them. Lor says "I did it last time!"
  • Done in The Boondocks when a famed rapper named Gangstalicious was reported to have been shot on stage.
    Huey & Riley: Again?!
    Sway: (exasperated) Again.
  • Bravest Warriors "Dan Before Time", when Future Danny travels back to the moment Danny is about to use his time machine and destroys it to prevent him from creating a Temporal Paradox or a Time Crash.
    Wallow: This happens every time you invent a time machine.
  • Also brought up in King of the Hill.
    Dale: (playing golf) Hey, if my balls lands on the back of a passing bird, which is then attacked by a larger bird who deposits it into the hole, is that still a hole in one? 'Cause that's how I'm gonna score it.
    Hank: Dale, it already happened once. What're the odds of it happening a second time?
  • A variant in Recess: School's Out, when T.J. frantically tries to tell his parents about the terrorists building a giant laser beam in the cafeteria of Third Street School, shortly after accidentally running into the sliding glass door to his house. His mother doesn't believe him, thinking that the bump on the head rattled his brain. When he runs off to the garage to tell his father instead, he just rolls his eyes and asks, "Did you run into the sliding glass door again?"
  • In the Steven Universe episode "Gem Glow", Lars lets out a baffled and frustrated "Again?!" after Amethyst uses her gem weapon to cut the dumpster behind the Big Donut in half.
  • In the Adventure Time episode "Graybles 1000+", this is Ice King's response to waking up with a broken leg.

    Real Life 
  • Texts From Last Night has this as its second most common trope (I'm sure you can guess the first.) This one is particularly nice:
    #1: Banned from zoo.
    #2: Again?
  • QDB
  • In one edition of Countdown, Keith Olbermann called out the TSA for detaining a high-ranking member of the British government who was working with the Department of Homeland Security because his name was the same as one on their watch list — and it wasn't the first time it had happened to him.
    "He's in the Cabinet! And we patted him down for weapons at Dulles Airport! AGAIN!!"
  • In Improv Everywhere's spontaneous musical I Love Lunch!, the character "Jeff" begins by standing on a balcony expounding upon how much he loves lunch, and his friend below tells him, "Jeff...don't sing a song, man..." Later, in the middle of the song, he can be heard saying, "He does this every day..."
  • Charles de Gaulle, leader of the French resistance during World War II and President of France after the war, was targeted by at least thirty assassination attempts during his presidency. He reportedly said "What? Again!?" during one such attempt.
  • In February 2015, after receiving a record amount of snowfall, this was the collective reaction from Boston when they found out they were getting another foot of snow on top of the three already there. The response was predictable.

Alternative Title(s):

Not This Shit Again, Not Again