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  • The Adventures of Jimmy Neutron: Boy Genius:
    • An episode involves extracting mitochondria from a virus. Viruses aren't cellular and don't have cells, and by extension don't have mitochondria.
    • In "The Eggpire Strikes Back," Jimmy states that because Cindy extracted the secret to entering his lab from Carl and Sheen and betrayed him to the Yolkians, that he's going to erase her short term memory so that she forgets. Thing is, this had happened the day before, so unless Cindy didn't sleep the knowledge would already have been consolidated into long term memory.
  • Ben 10:
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    • In an episode, some cows and a human were turned into mutant monstrosities due to exposure to an alien mutagen. Fortunately, they were "only briefly exposed", so the mutation reversed itself by the end of the episode.
    • The sequel series Ben 10: Alien Force features numerous human/alien hybrids, biologically impossible enough on its own. One of these has a nonhuman parent of a species made of fire.
  • In an episode of the short-lived The Buzz on Maggie, Maggie's older brother zaps her with a hand buzzer, resulting in X-Ray Sparks. For those who have never heard of the show, it's a high school comedy involving insects. Insects do not have inner skeletons.
  • In the Courage the Cowardly Dog episode "The Magic Tree of Nowhere", when Eustace accidentally wishes for Muriel to come down with an illness, Courage is tasked with making a cure with honey from a hornet's nest. While some species of hornets and wasps can make honey, it's only produced in small amounts and is not fit for human consumption.
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  • In Danny Phantom, failed cloning resulted in a female, younger version of Danny, named Danielle, who would devolve into ectoplasm if she used her powers. She got better. Cloning should produce a younger version, just a fair bit more so than the cartoon likely portrayed. The entire thing was an obvious reference/homage to the '90s Clone Saga from Spider-Man, which similarly botched cloning in many, many ways.
  • Done in The Fairly OddParents! episode where Timmy's Dad's first time on the Are You Smarter Than a 5th Grader? spoof, "Are You Brighter Than a 6th Grader" had him answer "sea cucumber" to nearly all the questions until the last one, "what kind of cucumber lives in the sea" prompting him to say the wrong answer. Forcing himself to re-attend school, Timmy's Dad retakes the competition and goes on a roll until the last question, "which sea vegetable would suit perfectly on an undersea salad", causes him to hesitate until he finds it in himself to say the right answer. In spite of the name, sea cucumbers are not cucumbers or vegetables in general, but animals — specifically echinoderms, like starfish. Regular cucumbers aren't technically vegetables, even.
  • Family Guy:
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    • Most of the jokes based on Joe's crippled status fall under this. Anyone who knows ANYTHING about paralysis knows the problem isn't the legs, it's the damage to the spine that keeps the legs or anything below the damage from being used. Leg transplants wouldn't repair the damage at all, correcting the damage to the spine would. Even stranger in that in one episode when he was cured, he got re-paralyzed by a gunshot wound to the lower back, and they also make a lot of jokes about how nothing else below the waist works very well. Like most things on the show, Joe's paralysis mostly seems to run on Rule of Funny. Never mind the Unfortunate Implications of all the cripple jokes.
    • At the end of the episode "Quagmire's Quagmire", Quagmire gets a call from his male-to-female father saying that she's pregnant. As explored on South Park when Mr. Garrison got a sex change, his father wouldn't be able to carry a child because the surgery wouldn't have given her the organs needed to do so.
  • Futurama:
    • Fry apparently survives a temperature of 109 degrees. In real life, people who reach a fever of 108 or more almost always die, and the few who do survive are left with major brain damage, because when the body gets that hot vital proteins start to break down.
    • Zoidberg is seen shivering as he claims he's cold-blooded. Cold-blooded animals don't shiver when cold.
    • The crocodiles seen in "I Second That Emotion" have overbites like alligators, instead of interlocking teeth. On the other hand, the alligators from "The Series Has Landed" are properly drawn with overbites, though their skin is green instead of black or gray.
    • In "The Sting", bee royal jelly is colored yellow instead of white.
    • Rabbits and hares are drawn with noses more like a cat's or a dog's than actual rabbit noses.
    • The scorpion seen in "Bender's Game" has six legs rather than eight.
    • From "Fry and Leela's Big Fling":
      • The proboscis monkeys are drawn without tails.
      • Many of the chimpanzees have their fur colored brown (real chimps all have black fur).
      • The gazelles in the zoo have body shapes and faces more like those of a deer than an actual gazelle.
    • The toucan seen in "Meanwhile" has three toes in front and one in back. Real toucans have two toes in front and two in the back like parrots, which in this series are drawn with only one toe in the back.
    • One episode involved the auctioning-off of the last extant tin of anchovies, a species which had gone extinct centuries before. There are no such species as "anchovy", as it's a catch-all term for any of 144 species of small fishes.
  • An episode of Garfield and Friends has Wade fall victim to one of Roy's pranks of chewing spicy gum. he later tricks Roy into chewing a piece himself. The thing is, with the both of them being birds, neither of them should be able to detect the spiciness.
  • Among the many errors regarding animal physiology and behavior, one of the more minor in Hero: 108 is the Deer King and his men, who neigh, grunt, and whinny like horses even though deer in real life make noises more like they have kazoos stuck in their throats or barking.
  • In one episode of Johnny Test, Johnny and Dukey go into their sisters' lab and take their ladybug when they run out of insects (which they used by photographing them in products and sending the pictures to the companies so they can get free stuff as an apology). Predictably, things don't go as planned as the ladybug is revealed to be highly unstable and grows into a voracious giant that threatened to eat all vegetation in its path, including an extremely rare giant pansy in Porkbelly's greenhouse exhibit. Unless it was a part of the subfamily Epilachninae (which are in fact herbivores and present a significant problem as crop pests), a majority of ladybugs (family Coccinellidae) people know are carnivorous and feed mainly on aphids. Most jarringly is that Johnny's sisters, who frequently tout themselves as geniuses, never point this out.
  • Much like the Warhammer example above, Jonny Quest: The Real Adventures has an episode where Dr. Quest foinds out that Moai statues that he is studying are resonant chambers, and by playing a certain tone could speed up evolution. They discover this by testing some odd-looking grass nearby, which has triple helix DNA. Jeremiah Surd uses this in QuestWorld to devolve Race and Benton into cave men, but only their minds. How this works is never explained since their bodies don't change (since simulations don't have DNA) and there is no suggestion that it can be used in reverse. It also doesn't explain why only certain things are targeted and others aren't, even if they're in range to be affected.
  • Justice League has a biological inaccuracy serve as the key plot point to a season 1 episode. In "Fury", Arisia attempts to wipe out all men on Earth with a deadly "allergen". Allergens are not contagious; different people (and different species) have different allergic reactions to the same substance. And crystals do not make something super-allergic! Also, the episode focuses on the sociological implications rather than the very glaring one of "All non-magically guided humans will die off very quickly with no men to participate in the reproductive process with." Yes, the villain grew up on an island of women who are created from clay and Greek god magic but pointing out to her that that's the ONLY place this happens might be helpful.
  • Justice League Unlimited character Vixen has the ability to gain the powers of an animal, represented by a ghostly animal shape that surrounds her. Okay so far. In one episode, she uses the power of a snake to grapple someone. Again, makes sense. However, the snake that appears is a cobra rather than a constrictor like a python or an anaconda.
  • Krypto the Superdog: Lex Luthor's pet Iguana and Harmless Villain Ignatius often gets himself into trouble using the Phlebotinum or technology of the week to catch an elusive bug or make them bigger, or in another episode, using a time machine to go to the past and try to eat a dinosaur egg. In reality, iguanas are complete herbivores, as any protein is harmful to their health. Although they may accidentally eat a bug or two in the wild, they never actively hunt for anything other than leafy greens, fruits, or vegetables.
  • The Marvelous Misadventures of Flapjack plays with this with how medical practices were back in the day with Doctor Barber. One infamous quote from him is, "Silly Flapjack. The human body is a complex system of pulleys and counterweights, all working to manipulate the food hole." This was probably intentional, given how the show revolves around a prepubescent sailor and his captain who uses a talking whale as a ship trying to find an island made of candy.
    • In the episode where everyone catches the plague, Dr. Barber needs the uninfected Flapjack's blood to make a cure. Vaccines are actually made by studying infected blood.
  • On Peg + Cat, Peg has an allergy to four-leaf clovers, which make her sneeze. This isn't biologically possible — four-leaf clovers aren't really chemically different from regular clovers other than possibly having a different gene that causes the extra leaf to grow, but whatever allergen would still be present.
  • Phineas and Ferb:
    • In one episode, someone pitches ideas for an "inaction figure" based on Perry the Platypus, one of which is "The Mad Marauding Marsupial of Death." Right continent, wrong order. The platypus is a monotreme, not a marsupial.note  Ferb has also stated that the platypus is the only mammal that lays eggs; apparently, he's never heard of echidnas. Also, in one episode Phineas states that platypuses are supposed to stay inside at night. One problem, platypuses are mostly nocturnal. Perry's behavior and appearance, in general, is nothing like that of normal platypodes (yes, that's the plural). He doesn't have webbed hands/front feet and his tail is more like a beaver's (the platypus is covered in fur all but for their bills and feet). Overlooking all this is seemingly played for Rule of Cool, though.
    • The ostriches in the show have three toes on each foot, instead of two like in real life.
    • Crows are drawn with yellow bills and feet when real crows have black bills and feet (save for the white-billed crow).
    • Alligators are drawn as more closely resembling crocodiles (i.e. V-shaped snouts, lower teeth visible when the mouth is closed). "Druselsteinoween" had a gator with a more correctly shaped snout, but unfortunately still has interlocking teeth. The intro of "OWCA Files", however, briefly showed gators with proper overbites, but the ones that appear later on are given crocodile-like mouths.
    • "Belly of the Beast" claims sharks have molars and incisors (they do not).
    • "Phineas and Ferb Save Summer" has a cave salamander that is colored more like a surface-world salamander and has fish-like gills. Real cave salamanders have feather-like gills, not unlike those of young salamanders or axolotls.
    • Dennis is shown to have pads on the bottom of his feet, something real rabbits do not have. He and the other rabbits in the show are drawn with stereotypical cat-like pink noses instead of slit-shaped ones real rabbits possess.
    • Pelicans are drawn with oversized bill pouches and generic bird feet with only three toes.
    • Maggie the Macaw in "The O.W.C.A. Files" would inconsistently have zygodactyl feet (accurate for parrots) in some scenes and ansiodactyl feet in others.
  • The Simpsons:
    • In "Treehouse of Horror V", Flanders ends up the ruler of the world and demands that everyone be happy and non-aggressive under his rule, or he surgically removes their frontal lobes to force them to be happy. Actually, damage (not to mention removal) of the frontal lobe would cause depression and aggressive behavior, not alleviate it.
    • The part in "Bart on the Road" when Bart and co. accidentally drive through the cornfield. Depending on the school, Spring Break traditionally takes place in March or April. While it was a funny joke, corn doesn't usually get that tall until early summer.
    • "Cape Feare" featured electric eels that have flickering forked tongues as if they're snakes, plus they're in a North American river.
  • SpongeBob SquarePants pretty much tear the book of the biology of marine life. The most common example is SpongeBob, Patrick, Squidward and Mr. Krabs having skeletons despite them being invertebrates. And Squidward is an octopus who has a lipped mouth underneath his eyes (and big, drooping nose!) instead of a beak in the centerpoint of his arms, which there is only six of instead of eight (although that was done on purpose to make animation easier). Not to mention Plankton (a copepod) being incorrectly referred to as a "single-celled organism" on multiple occasions, either by himself or others (C'mon, he's not THAT small!). And Sandy is supposed to be a tree squirrel but she hibernates like a ground squirrel, and she also has a pink, hairless nose like a cat.
  • 1973/74 Super Friends episodes:
    • "The Shamon U". A miniaturized sperm whale returns to normal size on a city street. It should be crushed by its own weight and be unable to breathe, but it's just fine.
    • "The Watermen''. When the title aliens extract silicon from sea water, it causes the sea water to immediately turn into red tide. Just one problem: red tide is caused by microorganisms, not a lack of silicon. This is lampshaded when Professor Matey notes that it should be impossible.
  • The Super Mario Bros Super Show! episode "Mario and the Beanstalk" features a garbanzo beanstalk covered in... pea pods. It isn't due to Unreliable Illustrator, either, since the veggies the Princess and Toad pull out from them to defeat a swarm of Hoopsters are unmistakably giant peas. Try not to think too hard about why garbanzo beans would grow into an enormous pea plant.
  • A group of Decepticons from The Transformers, known as the Predacons (whom, believe it or not, are actually the ancestors of the Predacons from Beast Wars), actually compose of Razorclaw (a lion), Rampage (a tiger), Divebomb (an eagle), Headstrong (a rhino), and Tantrum (a bull). In real life, the alt-modes of the last two are supposed to be herbivores — very vicious herbivores, but herbivores just the same.
  • Yin Yang Yo! had at least two instances considering the like:
    • In a few episodes Yin and/or Yang throw up; however, since that they're rabbits, they shouldn't be able to barf. Truth in Television states that rabbits are incapable of vomiting. Real rabbits lack opposable thumbs, bipedal locomotion and the ability to vocalize in English, so perhaps they possess more non-lagomorph characteristics than strictly necessary for the sake of story and audience association purposes.
    • In one episode, Master Yo once suggested that he was related to raccoons, which was a popular scientific theory... once. Genetic testing conclusively proved otherwise years before the episode aired; now, it's generally accepted by zoologists that pandas are members of the bear family, even if their unusual bi-colored fur makes them the black (and white) sheep of that family.

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