Once associated with Polynesian music (though it was originally a Portuguese variant on the guitar), since the 1990s the ukulele has since become associated with quirky young people. Most examples are women, with males preferring acoustic guitars (and, overall, singing more sentimental songs). Their youthfulness and weirdness is accentuated by the fact they like such an obscure, light sounding instrument as the ukulele.
The character doesn't necessarily even have to play the ukulele. They can just have a ukulele-themed leitmotif.
This became a Dead Horse Trope in the 2010s due to overuse. Ukuleles in relation to quirky characters are more often mocked than played straight.
- In the VeggieTales movie Gideon, Tuba Warrior, Bob gets pressed into service during the segment of the show that usually contains "Silly Songs with Larry", because Larry (and the other Pirates Who Don't Do Anything) are busy running the rest of the program. The chosen number is a ukelele karaoke called "Lance the Turtle", which ultimately deteriorates into gibberish.
- The irritating and somewhat eccentric Louie played by Adam Sandler in Mixed Nuts brings his ukulele almost everywhere with him. From writing a song in an attempt to woo Catherine (and comforting Chris with the same song) to providing accompaniment while the gang sing Deck the Halls as they carry a dead Stanley down the street with them.
- Ginger in Splendor in the Grass (1961) is an early Unbuilt Trope example. She's a liberated Flapper girl who wants to be an artist and is far hipper than anyone else in her small town, and her main hobby is playing the Ukulele, which she plays along to Jazz records. She dates many men, who clearly see her as a fun breath of fresh air, but unlike in later examples she's not a Manic Pixie Dream Girl. Instead, her promiscuity ruins her reputation and is implied to stem from some sort of mental issues.
- Parodied in the Saturday Night Live segment "Being Quirky with Zooey Deschanel", which spoofs Deschanel (played by Abby Elliot)'s spacey brand of "quirky". She's playing a ukulele in the theme song.
Deschanel: But the best kind of girl is a quirky girl! [meows at the camera]
- The Mother in How I Met Your Mother is shown in the final season to be exceedingly quirky, and owns a ukulele which is her signature instrument. In fact, she owns it specifically for quirky reasons: she was given it so that she can accompany her breakfast foods as she makes them sing show tunes.
- Rowan and Martin's Laugh-In. The musician Tiny Tim is best remembered for singing the song "Tiptoe Through The Tulips" in a falsetto voice while playing the ukulele on the show.
Dan: Tiny has added a bit of choreography to his usual presentation.Dick: There is nothing usual about Tiny Tim's presentation!
- Scrubs: Ted's Love Interest, Stephanie Gooch, plays ukulele for kids in the hospital. She's quirky enough to find the balding, sad-sack, incompetent, a-capella-singing attorney attractive. And can play "Carry On My Wayward Son" on her ukulele. And she hates being lied to.
- In one episode of Criminal Minds, Penelope, a FBI technical analysts known for her bright and colorful outfits, bubbly personality, and sharp wit, is shown taking ukulele lessons. This is yet another aspect of personality that contrasts against her darker, much more sedate coworkers.
- Shelley, the quirky daycare owner who once made out with Jimmy from Raising Hope plays the ukulele. She uses it partly for fun, and partly to teach lessons to the babies, seniors, and dogs in her care. (Both Shelley and Gooch were were played by Kate Micucci, one half of the musical comedy duo Garfunkel and Oates.)
- Crashing: Lulu is a young woman who plays the ukulele and she's desperate to be more unconventional than she truly is deep down. She calls her instrument uku-Lulu and plays some strange bits for fun. Lampshaded when she meets Kate: "Is that a ukulele? Wow, quirky!"
- Amanda Palmer:
- Amanda has her Ukulele Anthem which is all about this trope. It's a satirical song about how ukuleles make people quirkier and happier.
- She uses the ukulele quite a lot in her live shows both in a quirky and a straightforward way, but it started out when she wanted to learn to play a quirky ukulele cover of Radiohead's 'Creep'. It proved so popular that she's been opening her shows like that often from that point on, and she also wrote some songs specifically for the instrument.
- Tiny Tim may be one of the most famous, if not Ur-Example, ukulele players due to his eccentric appearance and personality. He made numerous appearances on Rowan and Martin's Laugh-In, and even had his first wedding hosted on The Tonight Show With Johnny Carson. He's perhaps best known for his rendition of "Tiptoe Through The Tulips," sung in a high falsetto voice while accompanying himself on the instrument.
- In "The Luau" from Homestar Runner, Marzipan, a textbook Granola Girl, throws a Luau party where the only food is a giant block of tofu, and the only entertainment is Maripan playing the ukulele to accompany Strong Sad's Polynesian poetry (which sounds like incoherent cooing). The whole thing is treated as pretty weird and boring by the other characters, but it all fits Marzipan's free-spirited personality.
- In Dumbing of Age, Danny's attempt at reinventing himself involves learning the ukulele, which he thinks will make people say "Look, it's Danny! With the ukulele! He's a good egg!" This is actually somewhat successful.
- The high-profile SCP Foundation administrator Dr. Alto Clef derives his name — among numerous aliases — by insisting that his True Name is an A major chord strummed on an ukulele, which he carries should others wish to address him by name. In the earlier years of the wiki's life, Clef was among several characters notorious for their large-scale and destructive tales and decommissioning assignments.
- Parodied in Gus Johnson's "white girl ukulele song", which is about a "quirky, random" girl who can only play ukulele in the key of C.
- Manic Pixie Dream Wife: Chance's manic-pixie-dream-wife Simone plays the ukulele. In episode "My Get-Well Juice" when Chance is in hospital, she plays her favourite instrument and sings him a song she wrote about toxins from plastic. (The song is a variation on "Littlest Birds" by the Canadian folk group The Be Good Tanyas.)
- On Joji Miller's Surreal Humor-laden Filthy Frank Show, one of Miller's many Cloud Cuckoolander characters was Pink Guy, who wore a pink Lycra suit and performed a number of bizarre and often deliberately offensive songs. When not rapping, Pink Guy tended to perform those songs in a crooning voice while accompanying himself on the ukulele, which made the Lyrical Dissonance all the more prominent.
- The titular character of Steven Universe is a quirky, slightly feminine boy who lives with his magical guardians, the Crystal Gems. A ukulele is his signature instrument, and most of the songs he composes In-Universe are played with one. However, by Steven Universe: Future he switches to acoustic guitar, and ends up giving his ukulele away to Pearl.
- British music hall and film comedian of The '40s George Formby became an unlikely screen hero because of his gawky misfit clown persona and his quirly ukelele-based songs. (Technically, he played a banjolele or banjo uke.)
- An off-the-wall comedian Frank Skinner who is a Formby fan and an accomplished ukelele player. His routines and songs present the ukulele as a musical instrument of quirkiness.