The eponymous protagonist of the series.
- Be Careful What You Wish For: Luther picked the Hercules Method in the hope of getting in better shape so that he could stand up to Paul and impress Petra. It worked so well he basically became a killing machine.
- Beware the Nice Ones: Luther is an exceptionally nice guy who also happens to be an industrial grade killing machine that walks like a man. As the Hercules Method is shown to be very corruptive, Luther holding on to his morality is nothing short of miraculous.
- Exemplified in the contrast between Paul and Luther's indulgent fantasy segues. Paul just imagines punching Luther to the ground and stomping on his head; Luther imagines crushing Paul's hand into a bloody stump and then sending his head spiralling off with a swipe of his hand.
- Beast and Beauty: With Petra by the time of Legend, although downplayed in that he still looks mostly human..
- Does Not Know His Own Strength: His weakness throughout Strange Talent. He damn-near kills Paul while holding back, and ends up killing his mother through his lack of control and The Librarian's Deadly Dodging
- Heroes Fight Barehanded: Though he's willing to fight with anything he can get his hands on, but Luther starts and ends most of his fights with his bare hands.
- Martial Pacifist: Throughout *Legacy,* he tries constantly to reason with his opponents and bring a peaceful end to conflict. It doesn't work out often.
- The Messiah: In the third series Luther had begun to forgive himself and seeks to redeem other students of the Hercules Method. It's very apparent as Luther constantly tries to reason with the other students even when the others seem completely beyond redemption. It even culminates with Luther killing Cain and despite the evil Cain has perpetrated along with the necessity of the action causes Luther to shed tears of sorrow over the fact that he could not reach Cain.
- Morality Pet: Serves as one for his girlfriend, Petra.
- One-Man Army: Luther has taken on and killed hundreds of criminals, some in batches of tens and twenties, and has proven more than capable of killing other students of The Method. Keep in mind that some of those students are historical figures that have themselves killed hundreds of people with a few of them killing hundreds in a single battle.
- Suicide by Cop: At the end of Strange Tale, Luther, having just lost everyone he cared about safe for Petra, and realizing he cannot do anything but harm people around him, lets the cops shoot him. Predictably, he doesn't manage to get killed.
- Unskilled, but Strong: Compared to other other students of the Hercules Method: all of them compliment him on how well he's developed, but point out he's uncontrolled and that his methods are unrefined in comparison to theirs.The Binder: See what I'm talking about? That's predictable Luther. And predictable- *hurls Luther across the room* -gets your ass kicked nice and good.Luther: *Kick Catch* Slow.The Binder: But not predictable. *kicking with the uncaught leg* See?
- Took a Level in Badass: Luther starts out as a scrawny geek with barely any muscle at the beginning of Strange Tales. The use of the Hercules Method gradually causes him to grow into a montain of muscles capable of shrugging off pretty much any form of injury and killing people with his bare hands.
- Top-Heavy Guy: By the time of Legend, he's developed from a scrawny geek, to a scrawny geek with super strength, to a ripped, but plausibly-muscled Hunk to this trope.
Luther's love interest.
- Abusive Parents: Her father would beat her.
- Badass Normal: Petra's able to fend off Method Users despite having no powers of her own.
- Blood Knight: She REALLY enjoys combat.
- Fiery Redhead: With a personality to match her hair color.
- Gun Nut: She affectionately refers to her arsenal as her "babies."
- Single Woman Seeks Good Man: This is why she falls in love with Luther even before he becomes a killing machine. She had enough of assholes after growing up under her abusive father.
- Sir Swears-a-Lot: Almost all of her dialogue is riddled with profanities.
- Undying Loyalty: Petra will never abandon Luther, no matter how difficult being with him may be.
The first series' main antagonist.
- Genius Bruiser: Is as intelligent as he is strong, which makes him very bad news to all concerned.
- Obviously Evil: He slaughers Paul's parents and wears his mom's apron, presumably, just so he can intimidate Paul into telling him about Luther.
- Oh, Crap!: Lets one out, right before Luther sneaks up on him and rips his head off along with his spine.
- Starter Villain: The first major antagonist, this makes him no less brutal than the others of the series.
- Everyone Calls Him "Barkeep": Like may of the students, he's only known by his moniker.
Two minor antagonists in The Legacy of Luther Strode.
- Blue Oni, Red Oni: The female twin is the blue, to the male's red.
- Boom, Headshot!: How Petra deals with the male twin.
- Broken Bird: The female twin is a war survivor, and is implied to have been pretty traumatized by the whole experience by the time she is adopted.
- Flirty Stepsiblings: They're adoptive siblings, but also shown to be in a romantic relationship in a flashback.
- Good Parents: They had loving parents and happy childhoods, they just go around killing people because they enjoy it.
- Not Blood Siblings: They're adoptive siblings and have been doing the nasty since their high school days.
- Older Than They Look: They were kids during the early 20th century, they look barely out of their mid 20s. Explained by the fact that the Hercules Method slows down if not even stops physical aging.
- Those Two Guys: They've been inseparable ever since the female twin was adopted by the male's family.