Protagonists: Chris Redfield | Leon S. Kennedy
Series canon: Resident Evil | Resident Evil 2 | Resident Evil 3: Nemesis | Code Veronica | Resident Evil 0 | Resident Evil 4 | Degeneration | Resident Evil 5 | Revelations | Damnation | Resident Evil 6 | Revelations 2 | Resident Evil 7 Biohazard | Vendetta
Spin-offs: Gun Survivor/DeadAim | Outbreak | The Umbrella Chronicles | The Darkside Chronicles | Operation Raccoon City
Other media: The Marhawa Desire | Heavenly Island
Voiced By: Ulises Cuadro
A drug lord running a small empire somewhere in the South American jungle. Hidalgo purchased a sample of the T-Veronica virus and unleashed several B.O.W.s on the surrounding villages, leading to Leon Kennedy and Jack Krauser getting sent in to investigate.
- Adult Fear: Watching your beloved child slowly die from an incurable disease. He also inflicts this on others, through kidnapping dozens of teenage girls.
- Anti-Villain: He just wants to save his daughter, by harvesting the organs of kidnapped girls and implanting them in his daughter, which he pulls off with his tyrannical drug empire.
- The Assimilator: Post-mutation, he bellows that those he consumes become a part of his mass. In his madness, he intends to absorb Manuela, with the intent of uniting themselves forever.
- Attack of the 50-Foot Whatever: Javier merges with the Veronica plant growing in his garden and turns into a monster taller than his compound.
- Bad Boss: When you finally assault his compound, he "welcomes" you with several zombies made from the former members of his army. He also murdered the two doctors keeping Manuela alive when she escaped.
- Big Bad: Of Darkside Chronicles, more specifically the "Operation Javier" storyline.
- Body Horror: A given, since he is the main antagonist of a Resident Evil game. Were you expecting him to not suffer a horrific mutation before the climax?
- The Cartel: The head of one, the Sacred Snakes.
- Crusading Widower: His wife died from the same disease inflicting Manuela, and Javier will do anything to save her.
- Even Evil Has Loved Ones: Javier started working with Umbrella because he hoped they would find a cure for his daughter's illness.
- Expy: of Pablo Escobar
- Human Traffickers: His organization dabbles in this, making it easier for him to provide the organs Manuela needs.
- I Cannot Self-Terminate: In a brief moment of lucidity, he begs Leon and Manuela to off him after enough damage is dealt to the plant that was controlling him.
- Knight Templar Parent: To save Manuela's life, Javier infected his daughter with a virus that causes horrific mutations. To counteract the mutations, Javier harvested organs from girls and implanted them in Manuela.
- Man of Wealth and Taste: Javier is a powerful drug lord, showing off his wealth with fancy suits and a lavish mansion.
- Moral Myopia: He's fiercely protective of his daughter, and terrified of losing her. So he has dozens of girls just like her kidnapped and murdered.
- One-Winged Angel: See Attack of the 50-Foot Whatever.
- Power Incontinence: He is swallowed by the Veronica plant shortly after his boss battle begins. Leon notes that he had not undergone the procedures required to keep the virus under his control.
- Sanity Slippage: Whatever was left of his sanity is completely gone when he allows the Veronica plant to amalgamate with him.
- When Trees Attack: He merges with a Veronica-infected plant and becomes a gigantic abomination of flesh and wood.
Voiced By: Amy Correa Bell
The daughter of the drug lord Javier Hidalgo. Kept alive by the T-Veronica virus, she is rescued by Leon and Krauser during the prequel story in Darkside Chronicles.
- Awesomeness Is Volatile: Too much blood loss, such as from tossing out bloody fireballs, and she'll incinerate herself.
- Achey Scars: Repeatedly throughout Darkside Chronicles, she clutches her arm in pain.
- Bad Powers, Good People: She's definitely good, but this series is notorious for having people who augment their bodies or gain special abilities as being evil.
- Beneficial Disease: The T-Veronica Virus cured her original illness and gave her fire powers, as long as she doesn't abuse them she'll be fine.
- Blessed With Suck: Sure, her powers are cool and effective... for ten minutes. Any more than that, and they'll kill her.
- Bloody Murder: Fire blood.
- Body Horror: Her right arm is necrotic. When unleashing her powers, it appears to be stripped down to the bone.
- Bodyguard Crush: She really does like Leon.
- Character Development: Becomes more proactive throughout The Darkside Chronicles. By the end, she comes to understand herself and her powers better, learning how to hold on to her soul and maintain control of herself by embracing both humanity and the pain that comes with it.
- Color-Coded for Your Convenience: She wears all white. She's naturally the '"pure" character in Darkside Chronicles.
- Damsel in Distress: She has the sense to break out and run for the heroes, though.
- Does Not Like Shoes: She's barefoot throughout the game, in spite of trekking through jungle.
- Dying as Yourself: Manuela has every intention of ending her own life, before she becomes a monster. Narrowly averted when Leon saves her in the Good Ending, but played straight in the Bad Ending.
- Earn Your Happy Ending: Throughout The Darkside Chronicles, we are shown numerous examples where virus infectees meet very messy ends. The end of The Darkside Chronicles says that Manuela coexists stably with the Veronica virus and is no longer terminally ill, very likely as a result of her personal growth.
- 11th-Hour Ranger: She's been with you for a while, but she'll join the fight against the final boss with her powers. She'll do most of the damage too, if you let her.
- 11th-Hour Superpower: Unleashes the powers granted to her by the Veronica virus right before the final boss fight. She's able to toss her blood out as large explosive fireballs, vastly speeding up the process of whittling down the final boss.
- Foil: To Alexia Ashford, especially as she is presented in The Darkside Chronicles. Both are Veronica virus infectees with similar powers, coexisting with the virus, but are at polar opposites on the morality globe.
- Freaky Is Cool: Krauser thinks so, at least.
- The Ingenue: She is soft-spoken as all get-out, but also intelligent and highly courageous. The naivety fades out as she comes to develop her own philosophy regarding the Veronica virus and its gifts, which certainly serves her better than everyone else who tried to use it for power.
- Innocent Blue Eyes: She has baby blue eyes, and is incredibly innocent in spite of her parentage.
- Ill Girl: Originally. By the end of the story she is cured by a combination of the Veronica virus and her own willpower.
- Leitmotif: "Manuela's Lullaby". She even sings it.
- Let's Get Dangerous!: Right before the final boss, she decides to quit sitting back, finally allowing herself to use her zombie superpowers.
- Mafia Princess: Her father is the head of a prominent Cartel, though she wants nothing to do with it.
- Mad Scientist's Beautiful Daughter: With regards to her father, Javier Hidalgo, a drug lord and bioterrorist.
- Playing with Fire: Having symbiotically bonded with the Veronica virus, Manuela can weaponize her blood to create flame barriers and hurl fireballs from the scar in her right arm.
- Red Right Hand: The bandages on her arm are covering scarring that is from her infection with the T-Veronica Virus.
- Scars Are Forever: Averted in the bad ending. Just before she dies, her arm heals up.
- Sweet and Sour Grapes: The essence of her relationship with the T-Virus within her. If the pain of living sickly gets too much, she can just let go and become a monster—that's the very basis of the T-virus, as Darkside Chronicles shows again and again. It is withstanding pain and holding on to both the good and bad in life that allows her to live with the virus, and Krauser and Leon's faith in her gives her a reason to do so.
- Unwitting Instigator of Doom: Several times over, and much to Manuela's horror. Her illness drove her father to extremes to save her, and her escape from her father's mansion aided in spreading the virus into the nearby village. She also helped inspire Krauser's Start of Darkness and was used to obtain a sample of the T-Veronica virus, which Simmons used in the development of the C-Virus.
- What Measure Is a Non-Human?: Somewhat discussed in Darkside Chronicles. Leon's only heard of psychos wanting the Veronica Virus or people horribly mutating if they were forced to contract it. He expresses shock that it was used as a treatment. Once he adjusts, though, he shoots down Krauser's idea that they should kill her before she becomes a threat.
The late wife of Javier, and mother of Manuela.
- The Dragon: The first and pen-ultimate boss of the game, sent to kill Leon and Krauser while her husband escapes.
- Dying as Yourself: In her final moments, she's able to regain control long enough to die peacefully.
- Even Evil Has Loved Ones: Javier's beloved wife, a relationship that gives both man and monster a measure of humanity. Even as a monster, Hilda still protects her husband from enemies and never shows any aggression towards Javier or Manuela.
- Ill Girl: She fell ill with the same disease that Manuela contracted, and supposedly died from it. Her husband's grief drove him to extremes.
- Innocent Blue Eyes: Manuela inherited them from her, and her eyes are blue when she's passive/in control of herself.
- Monster Is a Mommy: Manuela's mommy, at that.
- Music Soothes the Savage Beast: Calmed by Manuela singing her childhood lullaby.
- Red Eyes, Take Warning: Glowing, red eyes signal that the virus has taken over and she's about to kill anything in her path.
- Soap Opera Disease: Her condition is never given much detail, beyond being some sort of terminal disease that only locals seem to contract.
- Tragic Monster: Transformed into a massive, tentacled aquatic beast by the T-Veronica virus. Even so, there's a fragment of her human mind lingering inside the beast.
- Unwitting Instigator of Doom: Inflicted a Career-Ending Injury on Krauser, leading to his Start of Darkness and eventual role in causing the events of 4.
- Was Once a Man: The twist of the final chapter, revealing the beast they've been fighting was once Manuela's mother.