: Adventure Time Spongebob Squarepants 2.0 and Wolf Boss have adventures with princesses Sabrina and Donkey. Velma is Spongebob and Wolf Boss' video game console.
: Aladdin Daggett (who sings as Prince Edward) was living on the streets until me met Belle (who sings as Ugly Duckling). After freeing Dr. Strangelove from the lamp, he must stop The Terminator (whose pet parrot is Stan Smith) from causing trouble.
: A girl falls through a hole into wonderland. And apparently, Alice in Wonderland Roger Smith is a lizard.
: Gumball, Darwin, and Anais live with their parents The Amazing World of Gumball Nickelodeon!Vicky and Rolf.
: American Dad Jackie Chan is an FBI agent married to Dian Fossey. They have two children: Gwen Tennyson and Edward Cullen. Raymond is their goldfish, and Discord is an alien in their home.
: The Angry Beavers James Bond and Aladdin are two brothers who live together.
: Animaniacs Billy, Wakko, and Dot live in a watertower, while Aang lives with his aunt Slappy.
: Arthur Christmas Marty is the son of Santa.
: As Told by Ginger Anne-Maria keeps a journal.
: Atlantis: The Lost Empire Dipper is determined to prove that Atlantis once existed. Gepetto then recruits Dipper to join Tai Lung's team, which consists of Ned Flanders, Blade, Grandmother Willow, O'Hare, Young Gloria, Monsieur D'Arque, and the Bride. Upon arrival in Atlantis, they meet a king and a princess.
: Atomic Betty Young!Kiara is a space explorer who befriends Sparky and X-5.
: Two members of the water tribe, Avatar The Last Airbender Dakota and her brother Jonny (later Cole Sear), discover Ichigo (the Last of His Kind) inside a glacier. They, along with Master Tigress of the earth tribe, travel the world while avoiding Prince Cheese of the fire tribe and his uncle Professor Lupin. (At the end of the series, Cheese and his uncle join the heroes so that he may fight his sister Iris West-Allen and their father Incognito.)
: Beavis And Butthead Starscream and Butthead watch music videos.
: Ben 10 Ed (who becomes Fred Jones as a teenager) turns into aliens. His cousin is Vicky as a teen.
: Bionicle: Mask of Light Fred Flintstone sends Goku and Ron Stoppable on a quest. Aiding them are Dexter, Doctor Claw, Tweety, Mr. Crocker, Aragorn and Sheriff, later on also Marie Kanker. They all fight to defeat the Red Guy.
: BIONICLE 2: Legends of Metru Nui Walker sacrifices his powers to Slade, Kakashi, Robin, J, Epps and Jack Sparrow to stop the Tasmanian Devil, who is disguised as Monk. Trying to hunt them down are White Knight and Dr. Drakken.
: Six new heroes (to reiterate: BIONICLE 3: Web of Shadows Greg Sanders, Puss in Boots, Eden McCain, Generator Rex, Jayne and Hohenheim) must follow the guidance of the mysterious Hiruzen Sarutobi to find the aptly-named Beast. Other guides include Edna Krabappel, Abe Simpson, Trunks, Yoda, and another mute. The villains this time are Sandy Cheeks and Alex Louis Armstrong.
: Upon crashlanding onto a gladiator planet, BIONICLE — The Legend Reborn Mayor Adam West unites the locals, including veteran fighters Batman and Amy Wong, the rookie Black☆Star, the "collector" Billy and wise village leader Turk against the armies of Adam Savage. Meanwhile the traitorous Conductor takes note of all this.
: Bobs Burgers Gene Kranz and Hubert Fransworth run a burger restaurant. Their children are Sheen Estevez, Inuzuka Kiba, and Anna Coleman.
: The Boondocks Sheldon Cooper and Yakko Warner are two brothers raised in the suburbs by Nute Gunray.
: Braceface Sissy is a teenage girl forced to wear braces.
: Camp Lazlo Mike is a monkey who attends camp Kidney with an elephant and a rhino.
: Five teenagers are given magical rings. From Africa, Captain Planet And The Planeteers Iago, with the power of Earth. From North America, Dipsy, with the power of fire. From the Soviet Union, Mai, with the power of wind. From Asia, Poison Ivy, with the power of water. And from South America, Arnold, with the power of heart. Together, their powers summon Rupert Giles.
: Chowder Goofy trains Todd to become a chef. Meanwhile, Goofy's rival Sister Mary Clarence has her own apprentice, Barbie, who has a crush on Todd.
: Codename Kids Next Door Bart Simpson, Ash Ketchum, Isabella, Drake Parker, and Sonny are crime-fighting children.
: Cow and Chicken Staci and Chicken live with their human parents (the father is Brian Griffin). Chicken attends school with his friends Don Karnage and Bill the lizard.
: Cyberchase Milo (along with two girls) must save cyberspace with the power of math.
: Dexters Laboratory Near 2.0 (later Cosmo) has a secret laboratory in his room, which his sister Michelle likes to invade. Their parents are Bunny Bravo and Roger Doofenshmirtz (season 1), then Mr. and Mrs. Possible. Cosmo's arch nemesis is Spongebob Squarepants in the later seasons.
: Dinosaur Train Beast Boy (later Ron Weasley) is a young T. rex who rides a time-traveling train through the dinosaur world with his Pteranodon family, namely papa Cobra Commander, mama Wanda and his siblings Sailor Moon, Penelope Garcia and Peter Parker. The conductor is Bender.
: Dora the Explorer Ben Tennyson travels with a Spanish-speaking girl.
: Drawn Together Roy Mustang, Lightning, Duncan, Captain Marvel, Princess Clara, Toot, Foxxy Love, and Bender are selected onto a reality show to share a home.
: Ed Edd N Eddy Jimmy Kudo, Izzy Izumi, and Mifune scam the kids in their neighborhood. Leela, Hallie Parker, and Lee sometimes give mischief to the boys. Lazlo is the boys' Funny Foreigner neighbor.
: The Emperor's New Groove Shaggy is "poisoned" by Mrs. Potato Head and Manny the Mammoth. He becomes friends with Uncle Phil.
: Enchanted Tiana is sent to another world by the evil Marsha Dale. While Tiana lives with Jon Arbuckle, Prince Joe Bradley and Rafael are trying to find her. Jon's love interest was Charlotte York. Annie Wilkes narrates the saga.
: Family Guy The Lumpy Space Princess, Fran, Gary Oak, Buffy, and Kyle, and Will live under one roof. LSP likes to drink out with Joey Wheeler, Chef Hatchet (whose father is Eduardo), and a Clone Trooper. Iroh is a Dirty Old Man, te Clone Trooper married Rangiku, and Diego is mayor.
: Feeling ignored by his parents The Fairly Oddparents Stifler's mom and Rico and abused by his babysitter Stacy Hirano, Mac finds his fairy godparents Sally O`Malley and Daffy Duck inside a magic 9-ball. Mac's teacher Gunther tries to catch the fairies, while the muscular fairy Sam also gives them trouble.
: Fanboy and Chum Chum Prince Naveen and Spike think they're superheroes.
: Fifi And The Flowertots Panini has adventures in her garden.
: Fish Hooks Pops, the first SpongeBob SquarePants, and Bea attend a school for fish. There's a Jerk Jock named Jake.
: After being bullied by his brother Foster's Home for Imaginary Friends Harold, a boy who becomes Phineas brings his imaginary friend Carey Mahoney to a special home run by Cow and her grandmother Perpetua. Abigail is a motor mouth, while Tweety likes chocolate milk.
: (2000s) The Fox and the Hound Kuzco, Pacha, and Mama Odie have an old woman adopt a fox, who becomes best friends with a hound. As the two grow up, they realize that their species were sworn enemies.
: Freakazoid! Wesley Crusher is a nerd who becomes a zany superhero named Scrappy Doo.
: Futurama Joe Kido arrives in the year 3000, where he meets Chief (sometimes Mr. Burns), Ginger Foutley, Slips Python, Astrid, and the first little pig. Captain America is madly in love with Ginger.
In the series finale, Joe and Ginger get married.
: Generator Rex Lord Shen is a living bio-weapon. Penny is a doctor, Superman is an agent, and Klaus is now a gorilla.
: Gravity Falls Dudley Puppy and Kitty Katswell are twins who reside with their uncle Major Monogram. Dudley crushes on Hayley Smith, who works at the gift shop.
: The Great Mouse Detective Chris is a criminal mastermind.
: Hey Arnold! Flapjack has adventures in his neighborhood with his best friend Lex Luthor. Flapjack's grandfather is Professor Farnsworth.
: Hi Hi Puffy AmiYumi Hannah Montana and Rose Tamas are in a band. Rarity 2.0 (sometimes Nickelodeon!Helga) is a Fan Stalker, who loves the band.
: Horton Hears A Who Peter Griffin discovers a speck on the plant he finds. Owen is the only son in the family who rarely talks. Owen's parents are Frankie Foster and a boy on the bridge. Frankie is also a scatterbrained scientist. Live-Action!Jasper is the Big Bad.
: Hotel Transylvania Rigby throws a birthday party for his daughter, inviting fellow monsters B.O.B., Missing Link, Miss Spink, Sandy Cheeks, Stefano, Skipper, and a mummy. Along came the human Ron Weasley.
: How to Train Your Dragon Chris Griffin becomes a dragon tamer; Violet Parr is his love interest.
: The Incredibles Nate marries Elizabeth Bennet. They have three children: Rapunzel, Mac, and a baby. Lisa Simpson resumes her babysitting job. Sebastian is the Big Bad of the film. Helena provides the heroes' costumes.
: Jimmy Neutron Arnold is an inventor who hangs out with Irving and Mandark (later Finn). Twilight Sparkle and Adult!Kiara are Arnold's rival.
: Johnny Test Dexter Douglas and his pet dog Don Karnage ask Dexter's sisters Mabel Pines and Louise Belcher to test their inventions on them. The twin sisters crush on Chester McBadbat, but SpongeBob SquarePants 2.0 is madly in love with Bubblegum, while Katara is a Stalker with a Crush on Dexter. Sam and Lightning take turns being a reporter. Skips and Batman are secret agents. The kids' parents are Wilt and Airachnid.
: Kick Buttowski Keswick becomes a daredevil, and Cleveland is his Funny Foreigner friend. Tyler 2.0 works at a convenience store, while the original Dexter torments his younger brother.
: Let Kid vs. Kat Wally Gator fight an alien cat.
: King of the Hill Michael Knight and Donna Tubbs live together in Arlen, Texas with their son Steve Smith and Donna's niece Susan Test. Their neighbors include the crazy L with his wife Lust and son Beast Boy, the Motor Mouth Snot-Rod, the pathetic Joker and the Laotian Butters.
: Kung Fu Panda Stifler runs away from his adopted father Chef to become a fighter like his idols Edward Elric, Luke Skywalker, Pinkie Pie, a crane, and Elle Woods. Their teacher Severus Snape assigns Stifler to fight Mace Windu, who has broken out of Gantu's prison.
: Lilo & Stitch Mad Scientist Shrek creates Prince Zuko, who crash lands in Hawaii and gets adopted by Lilo. Her sister LeShawna has to deal with Zuko's mischief while also trying to keep a Social Services worker named Jake from taking Lilo away. Meanwhile, Shrek and his partner Pippin are trying to find Zuko before Captain Norbert.
: The Lion King Nigel Uno wants to be like his father King Richard (whose assistant is Dr. Mephisto). But out of jealousy, Richard is killed off by his brother Shredder (who had plotted with Sister Mary-Claire, Bruce, and a Mexican. Nigel then leaves the kingdom and falls under the care of Gaston and Ralph Bighead. Eventually, Nigel grows up into the Joker and his childhood friend Chrona Makenshi, the daughter of Frau Farbissina, becomes Miranda. Miranda and the Joker are brought home by Rafiki so Joker can fight his Evil Uncle.
: The Little Mermaid a singer dreams about living in the real world. She goes to an acting teacher to become a human. Jor-El is a reggae-singing crab. The singer falls in love with Prince Jeremy, while Mung Daal is a seagull. Bart is a flounder.
Return to the Sea: The singer has a daughter named Mary Test , who decides to dream of becoming a mermaid, which is the opposite of her mother.
Ariel's Beginning: The singer, who is now Giselle, is back and she joins New!Flounder, Jor-El, and his band members in a quest to restore music to the kingdom. Meanwhile, Marina Del Rey is trying to take Jor-El's job.
: The Looney Tunes Show Oscar and Bugs share a home, as Becky Hicks is a Stalker with a Crush on Bugs.
: The Lorax Double D goes on a quest to find the last tree in the land.
: Madagascar Harold, Captain Kirk, Quagmire, and Nicky get stranded off their zoo and onto an island, where they meet the lemur tribe, their leader Klaus and his aides Bev Bighead and Spiderman. Meanwhile, Peter Griffin, Bartok, MacSquizzy, and Pinocchio are spy penguins.
Madagascar 2: In which Klaus became Dr. Drakken, there's a tribe of Harolds, Quagmire becomes a doctor, Nicky falls in love with Beta, and Kirk reconnects with his family,
Madagascar 3: The animals find their way to Europe, meeting the circus performers Pinkie Pie, Tai Lung and Ratigan. A bounty hunter is following them.
: The penguins and the lemurs (Bev Bighead now being The Penguins of Madagascar Captain K'nuckles) return to the zoo, where the penguins become best friends with Nala and rivals with the lemurs. They sometimes fight a dolphin named Ling-Ling. Geoff is now an alligator, whereas Jake is a rat king.
: Mad Jack The Pirate Agent Mudler the pirate and his rat sidekick Arthur have adventures together.
: The Marvelous Misadventures of Flapjack Doctor Claw trains a little boy named Pelswick to become a great sailor. They live inside Francine. Claw and Pelswick often beg Spike for candy.
: The Mask Hank Hill is a shy banker who's colleagues with Blade, but has a superhero alter-ego whose arch enemy is a mad scientist named The Doctor.
: After defeating his sworn enemy Megamind Batman, Al Swearnegen and his minion Gob build a hero out of Dink, the Little Dinosaur. Sandy Cheeks is a reporter.
: Mulan Jane follows her father into the army.
: My Gym Partners A Monkey Dash is a human attending a school for animals, where his partner in gym class is James "Sawyer" Ford. Other students include Dr. Blowhole and Dawn Summers.
: My Life as a Teenage Robot Skippy Squirrel has a crush on a teenage robot.
: My Little Pony: Friendship Is Magic Mary Jane Watson, Azula, Sierra (later Princess Bubblegum), Hinata, Martha, and Toph are ponies. Mary Jane's best friend Lex Luthor has a crush on Sierra. Azula's sister Samara will later start a secret club. Sora is an evil princess, and Violet Baudelaire bullies Samara's clubmates. Earl goes overdrive into Chaotic Evil.
: Once Upon a Forest Harmony falls victim to toxic fumes, staying home with her uncle. Wendy Corduroy, Bart, and Edgar have to find a cure for her.
: Phineas And Ferb Adam Lyon and Chowder make inventions in their backyard. Their friends include Tristan, Beavis, and Numbuh 3. Sometimes, Cameron, who is bullied by his brother Kuzco, joins Adam and Chowder on their adventures. Their pet platypus, under the orders of Francis Griffin (later Grunkle Stan), and (sometimes) an intern named Mordecai, fights Dukey, whose daughter is Sadie (later Meg Griffin). Dukey is jealous of his brother Scooby-Doo, who is the town's mayor. Their sister Pearl (later Beth) is friends with Lindsay and Jenny Brown. While she is not telling Gabrielle and Michael Dawson, she crushes on InuYasha. Meg dates Monty Monogram later in the series. Three has a crush on Adam.
P.S. Beth and Lindsay actually met on the set, where the former replaces Pearl.
: Three girls (Blossom, Bubbles and The Powerpuff Girls Blaineley) created by Prince Charming fight Al Bundy.
: The Princess and the Frog Ariel, inspired by her late father Beast, dreams of opening up her own restaurant. Gantu is a voodoo doctor who turns prince Justin into a frog, so he kisses Ariel and she becomes a frog. On their journey, they befriend Shrek the alligator and Genie the firefly.
: After a vision of his idol Ratatouille Maurice, Hercules becomes a chef, befriending the human Boots.
: The Real Ghost Busters Prof. Utonium (later on Brian Griffin), Mojo Jojo, Stan and Superman battle the paranormal with the help of friendly ghost Philip J. Fry and their secretary, Jessie.
: Regular Show Cartman is literally "The Coon"; he and his roommate Agent Jay work for Dexter 2.0. Their coworkers include a lollipop named Franklin, Captain K'nuckles the yeti, and Tom Tucker who hangs out with a ghost.
: The Replacements Ferb and his sister live with their adopted parents.
: Rio Eric Forman's owner Toph sends him to Brazil, where he must mate with Ginormica.
: Rock-A-Doodle Heather finds herself on a cartoon farm, where she meets singer Dick Dastardly and B.A. Baracus. Maurice is the Big Bad.
: Rocko's Modern Life Dobby has adventures with his friends Chef and the mayor of Whoville. Dobby's neighbors, Duckworth and Mr. Krabs, hate him.
: Sabrina The Animated Series Dee-Dee is a teenage witch; interestingly one of her friends is Dee-Dee's real life brother Harold.
: Scooby-Doo The original Beth, Sadie 2.0, Linguini, and Mr. Crocker are teenage detectives; and Dexter's first father is the Team Pet.
: The Simpsons Dave Starsky marries Una Alconbury, and they have 3 children: Elroy Jetson, Atomic Betty, and a baby.
: Sonic Underground Brick, Sonia, and Manic search for their mother the queen.
: South Park Sousuke, Michael Corvin, Spider-Man, and Vegeta are four Colorado boys. Wheeler is Vegeta's father.
: Spongebob Squarepants Kahn Souphanousinphone (later Arthur, and always sings as Spike) lives in a pineapple, next to Zoidberg. Arthur's best friend is The Tick, and he and Zoidberg work for Jerry, whose daughter is Candace. His business rival is Eustace ( Cat since The Movie). Also, Kylie Griffin is from Texas.
: Star Wars: The Clone Wars InuYasha is a Jedi in training under Jimmy Trivette, whose other apprentice is Sabrina. Pinkie Pie (later Sakura) is Inuyasha's love interest.
: Superman The Animated Series Agent Simmons is the man of steel.
: A king sends his daughter Sym-Bionic Titan Astrid to earth.
: Tangled Princess Ilana wants to see the real world, but her "mother" Agent Scully won't let her leave the tower, not even on Ilana's 18th birthday.
: Teachers Pet George Jetson disguises himself as a human to attend school with his owner Finn, whose mother Bo Peep is their teacher.
: Teen Titans Naruto gathers a team of superheroes, including Nick Stokes, Trixie, Ugly Betty, and Aang, to fight Tony DiNozzo.
: The Tick Brainiac and his sidekick Bummer fight crime.
: Total Drama Island Carl Karl and Krusty the Clown gather 22 teenagers; including Jimmy Neutron, Cleveland Brown Jr., Applejack, Mark Lilly, Jojo McDodd, Chouji (later Wade), Kick Buttowski (later Quentin Costa), Bud Bundy, B-Mo (later Candace), Vanessa Doofenshmirtz (later Kate Gosselin), Mokuba (later Rika), Benson, Tailgate, Wheeljack, Misty, Megan Morse, Daffy Duck, Lola Bunny, Kate Austen, Princess Melody, Xena, and Luanne Platter; onto an island so they may win a million dollars. (Jojo wins season 1 and Candace won season 2)
Arriving in season 3 are Buttercup, Harvey Dent (who won the season), and Rarity (the latter of whom has a crush on Bud).
13 completely new teens arrive for season 4: Mother Gothel, the Gossip Girl, Chenault, London Tipton, Sharon Spitz, Bra, Disney!Jorgen Von Strangle, Richard Watterson, Wooldoor, Dick Casablancas, Tina Belcher, Huey Freeman, and a mute guy. Tina wins this season.
13 new teens (7 men and 6 women) arrive in the second half of season 5. An original contestant and a newbie both win this season.
: Totally Spies! Mr. Krabs hires 3 teenage spies: Libby, Joey Potter, and Michelle.
: Transformers Prime Palpatine leads a group of heroes made up of Fanboy, Tsunade, Zapp Brannigan, a guy who doesn't talk, and Batman. Chris Griffin joins them later on, and Trent sometimes helps them out. Randy Marsh dies in the first five episodes. Meanwhile on the bad guys side, Eduardo is the leader with Wooldoor Sockbat, The Mentalist, Spirit Albarn, Mrs. Possible, and another mute guy working for him. The humans of this series include Timmy Turner, Yachiru Kusajishi, Emmett Taggart, Timmy's mother Jasmine, and Winston Zeddemore on the good guys' side and Aquaman as a bad guy. Captain America turns into an ambulance on some occasions.
: Transformers Rescue Bots Ragnarok, Muscle Man, Envy, and Stephen Hart are a group of emergency responder Autobots who've arrived on Earth. Carter Pewterschmidt (later Plankton) then assigns them to help a Badass Family, including Mr. Mackey, Cody Martin, Carlos Lopez, Asohka Tano, and Ron Weasley. Sasuke Uchiha is a scientist, the mayor of the town is Monkey, and Jake is a reporter. Aqualad is an evil inventor.
: T.U.F.F. Puppy Noah and Katie fight crime, often against Kowalski... and everyone's a Funny Animal. Their boss is Grandpa Phil. Isn't Albert an inventor?
: Ugly Americans Roger is the Token Human in a city full of monsters.
Wally Gator: So now Gabumon is running out of zoos.
: Whats With Andy Franklin is a prankster.
: Young Justice Nick Jonas, Gerald, Sonic, Aqualad, Goo, and Artemis are a team of superheroes. Their mentors are Brock, Jeremy Johnson, Lawrence Fletcher, Adult Kovu, Green Arrow, and Red Tornado. Jeremy's married to Courtney; Brad is Mr. Twister.