- Six Teen:
- 101 Dalmatians: The Series: Spinelli is a hot-headed and adventerous Dalmatian puppy who goes on adventures with her hungry brother Copper, optimistic sister Haruhi Suzumiya, and neurotic chicken Wilma Flinstone, usually thwarting the plans of Yzma and her henchmen, Iago and Papa Smurf (later Billy). Mandy is Yzma's niece, whereas Gurgi is a tough mutt with his own gang of Dalmatian pups. Wakko is the leader of the "Bark Brigade", along with Skroopf and Gonzo. Freakazoid! (later turning back into Dexter Douglas) is Spinelli's rival. The pups' parents are Roger and the spider. Their owners are Donatello and Babs Bunny, along with Fairy Godmother.
- The Adventures of Jimmy Neutron: Boy Genius: Aidan Keller is a boy genius whose best friends are Carlos and Fegelein. Dora and her Black Best Friend Clover are Aidan's rivals. Clark Kent and Gloria are Aidan's parents.
- Adventure Time: Oz and Kenny have adventures with princess Beth. Rarity is a rainbow unicorn, and Pops is an evil king.
- All Hail King Julien: Sparky becomes king after his uncle Agent Hudson abdicates. Sparky's servants are Simba and Fred, and Juno is the special ops expert.
- Almost Naked Animals: Randall Boggs, Milly, Sailor Moon, Carl the Evil Cockroach Wizard, Norm, Alex P. Keaton, and Larry Moss live in a hotel for animals.
- The Amazing World of Gumball: A squirrel has adventures with his goldfish brother and rabbit sister Sofia the First. Courtney and Gaara are the parents.
- American Dad!
- (France) Superman is now an FBI agent working for the Black Ranger. In his private life, Superman is married to Guinan and they have two children: Manny Garcia and Stacy Hirano. Also living with the family are Chon Wang the alien and a fish who was sometimes Pegasus Seiya.
- (Canada) Rambo is an FBI agent working for Peter Griffin. Rambo is married to Mittens and they have 2 children: Hermione Granger and Christopher Robin. Dr. Cockroach is their fish, and Maxwell Smart is an alien.
- Animaniacs: Peter Pan, Billy, and Mary live inside a water tower.
- The Angry Beavers: Frasier and Simba are brothers who live together.
- Atomic Puppet: Chandler is turned into a sock puppet by Koroku and teams up with Phillip J. Fry, who can put him on his hand to become a superhero. Fry's best friend is Lana Kane and his parents are Tonzura and Moaning Myrtle.
- Avatar: The Last Airbender: 100 years into the future, Penny and Kelso discover Zack and Cody inside a glacier. Along with Cindy Vortex, they are followed by Jake Long and his uncle Albus Dumbledore. In the end, after dealing with arcvillains Jake's rival Carlos Solis and Evil Chancellor Dr. Doofenshmirtz, everyone fights Jake's sister Claire the cheerleader and their father Kolya (later Alec Trevelyan, then Roger Smith).
- The Legend of Korra: The reincarnation of Zac and Cody (now Near), Zoé Kezako, is mentored by Penny's (now Phyllis) and Near's son another Roger Smith. She is joined in her quest by brothers Simon and Drake Parker to fight David Palmer and his Dragon J'onn J'onzz. Other local figures include Sleazy Politician Jason Stackhouse and Cindy's daughter police commissioner Shego. Zoe's father is Chase Young, and Kelso is still himself. Ace Gecko was a bloodbending gangster.
- In the second season, Shadow the Hedgehog attempts to profit off a civil war, and it's revealed that 10,000 years ago, the Avatar was created when King fused with Ephiny to defeat the spirit of chaos, Mr. Gus.
- In the third season, various people get airbending powers after a spritual event, including Prince Eric.
- The Backyardigans: Minka Mark the penguin, Finn the moose, Timmy Turner the thingy, Sakura Haruno the hippo, and Gwen the kangaroo have adventures in their backyard.
- The Batman: Xemnas is a young hero whose sidekicks are Fuu and Philip J. Fry. The villains include Lord Dragaunus, Homer Simpson, William Stryker, Daido, Salem Saberhagen, and Chloe Sullivan. King James is Xemnas' butler, and Fuu's father Gloin is the police chief. Other officers include Vilgax, Gwen Tennyson, and Sherlock.
- Batman: The Animated Series: The Genie and his sidekick Fox Mulder (with the occasional assistance of their butler Pennywise) assist police officers William Stryker and Galaxxar in apprehending the most terrifying criminals: Monster Clown Doc Brown, fallen friend Basil Exposition, Gentleman Thief wannabe Brooklyn and master of fear Pinky.
- Batman Beyond: When Marshall's father gets killed by Captain Panaka's henchman Auger, he succeeds Hagrid as a superhero. Lee Kanker later learns of Marshall's secret life. Ruth DeWitt Bukater is the police chief.
- Batman Beyond: Return of the Joker: Finn is Back from the Dead with his new loyal followers - including Nappa, and twin sisters Emma Frost and Mary Jane Watson. Ruth tells Marshall the story of Finn: after he and Paula kidnapped Hagrid's sidekick Yang and tortured him for weeks, Yang eventually snaps and seemingly kills Finn. After retiring as Hagrid's sidekick, Yang eventually grows up to be Obadiah Stane.
- Ben 10
- Ben 10: Skippy Squirrel finds a device that turns him into various aliens such as Nicolai, The Janitor, Dr. Romano and Solomon Grundy. Alongside his cousin Bubbles and their grandfather Maximus, Skippy fights villains such as Galactic Conqueror Panthro, Creepy Child Black Canary (later Magneto), Doug the ghost, Mad Scientist Gazpacho, Evil Sorcerer Big Mike and his niece Bessie.
- Ben 10: Alien Force: Skippy has grown up into Dingodile. Alongside his cousin (now Jinx), his former enemy Magneto (now Shinji Ikari) and his girlfriend Joey Potter, Dingodile fights villains such as Eric Forman (Steve Smith in Ultimate Alien), Panthro, and Lydia Deetz (formerly Bessie).
- Ben 10: Ultimate Alien: Ma-Ti reveals Dingodile's powers to the outside world, which earns him the hatred of TV host Spider-Man, yet he still has to save the world from Aquaman.
- Ben 10: Omniverse: Leeron has joined Dingodile after Shinji and Jinx are off to college. Maximus has become Cave Johnson. General Hakuro is The Dragon to Whiplash and Mad Scientist Stifler. Leeron and Dingodile later fight Emperor Ding Dong Daddy.
- Beware the Batman: Sylar fights crime with his butler Charles Xavier and swordswoman Mom. Gloin is the police chief who has to learn to trust Sylar. Recurring villains include Gretchen, Star Johnson, and Abner and his sidekick Stefano.
- BoJack Horseman: Papa Bear is a washed-up sitcom star who lives with Lazlo. Papa Bear's agent/girlfriend is Nico Robin, and his ghostwriter is Margaret (who is dating Gai.
- Bonkers: MacGyver is a washed-up cartoon character who becomes a police officer, alongside T.J. Hooker.
- Brandy & Mr. Whiskers: Dee-Dee and her father are trapped in the jungle.
- Camp Lakebottom: (Canada) Sean, Sierra, and Edward Cullen attend a freaky summer camp, where the counselors are Bear, Beaver, and Mr. Chow. Sean's sister Tiana attends another summer camp with his rival Stephen Stills.
- Camp Lazlo: Milo, Orochimaru, and James attend Gustavo and Jiraiya's summer camp.
- Captain Planet and the Planeteers: Swanney (later Eddy), Vegeta, Didi Pickles, Scarlett, and Freddie Benson are five youths who summon Earth's greatest hero... Albert.
- Chowder: Chef Giles and his wife Clotho train Denise to become a chef like Giles. Giles' rival, Agent K has Velma as her apprentice, who has a MASSIVE crush on Denise.
- Clone High: Harold, Starscream, Chopper, Zoro and Jessie are high school students, cloned from historical figures by Principal Crocker, his robot butler Jacob Black, under the orders of V.V. Argost. Mordecai sings the theme song.
- Code Lyoko: Zoey, Abigail Lincoln, and Caitlin Cooke go into the computer world with Vivi. Raf Esquivel stays outside as the programmer.
- Codename: Kids Next Door:
- Corneil And Bernie: Dave the Barbarian meets a talking dog named Dr. Drakken.
- Cow and Chicken: Stu and the Beast are the inhuman children of Kitty Forman and Goku. Wakko Warner is bad at disguising himself. Beast's classmates are Gob and Stewie Griffin.
- Cyberchase: Three kids and their bird save cyberspace from a green man and his robots, one of whom is Rock Lee.
- Danny Phantom: Carl Wheezer has ghost powers. His best friends are Cleo Carter and Jimmy Olsen. Carl's parents Robert Goren and Carrie Bradshaw are ghost hunters, while his sister Strawberry Shortcake just wants to lead a normal life. They are all taught by Patrick Star.
- Darkwing Duck: Father Time takes up a life of crime-fighting with his adopted daughter Bud Bundy and pilot Maester Luwin. Occasionally working for Spy Master Winnie the Pooh and Obstructive Bureaucrat Batman, Father Time fights baddies such as Umibozu, Buster Bunny, Nigel Thornberry and even Father Time's evil counterpart Jack Dalton.
- Dave the Barbarian: Montana Max and his sisters patrol the kingdom.
- Dexter's Laboratory: Toast has a secret lab in his room, which his sister Trixie Carter often intrudes. Their parents are Libby and Johnny Bravo, and Toast's rival is Izzy Izumi.
- Dragon Booster: Rodney, Tamika, Veemon, Bugs Bunny, Duke Nukem, Nathan Petrelli, Bobby Hill, and several others race horseback on dragons (really dinosaurs).
- Drawn Together: Manny Rivera, Ringo Starr, Cartman, Dexter Douglas, Sabrina Spellman, Troy Bolton, Mulan, and Jane Lane are cartoon characters sharing a home.
- DuckTales: Gargamel is the richest duck in the world. He has to take care of his grandnephews (Buttercup, Scooter and Dennis the Menace) after his nephew Pumbaa left for the navy. He hires Daphne Blake as a housekeeper and nanny. Daphne’s granddaughter also happens to be Wendy. Gargamel’s friends include his butler C-3PO, Captain Crash Maester Luwin, Bungling Inventor Alfred Pennyworth, and Maester Luwin’s biggest fan Elroy Jetson. His rogues gallery consists of the second richest duck in the world AKA Winnie the Pooh, the Beagle Boys (led by Terrence “Terry” Lewis) and the sorceress known as Madame Web.
- Dude, That's My Ghost!: Kurt Hummel meets the ghost of pop star Kim Jong-il.
- Dungeons & Dragons: Billy Nolan the Ranger, Sailor Mars the Acrobat, Julia the Thief, her brother Lelouch the Barbarian, Raymond the Cavalier, and Eek the Magician find themselves in a magical world.
- Ed, Edd n Eddy: Buster Baxter, Jimmy, and Zapp Brannigan scam the kids in their neighorhood.
- El Tigre: Pasadena Paul is a kid with a cat-themed alter ego.
- The Fairly OddParents!:
- (Belgium) Ulrich finds Dipsy and Drew Saturday inside a magic 9 ball. Ulrich's father is Manny Bianco. Lindsay is an evil babysitter. Ulrich's bet friends are Master Splinter and Miss Valentine, and Hiro Nohara is a fairy obsessed teacher. Ash Ketchum is Ulrich's rich rival. Ulrich has a crush on Naruto.
- (France) Dr. Manhattan and Yuria are the fairy godparents to Leo, whose parents are Mr. and Mrs. Neutron. Green Lantern is Leo's school teacher, and Kari is his evil babysitter. One of Leo's best friends is Cobby. Leo has a crush on popular girl Judy Hopps. Eventually Manhattan gets pregnant and gives birth to a baby, whose Evil Twin is the announcer for Disney Infinity. Kari's sister Yuna has a crush on Leo, Marge Simpson and Master Yo send their alien son to earth, where he falls in love with Kari. Leo later gets a pet Fegelein, and he is later forced to share his fairies with Clover. Mr. Neutron is jealous of his neighbor Fox Mulder.
- Family Guy
- (France) Cat, Shenzi, Tucker Foley (later Henry), Edd, Padme (Lisa Simpson in a direct-to-DVD video), and Al Bundy are a Rhode Island family.
- (Canada) Danny Ocean, Laa-Laa, Captain America, Dakota, Alejandro, and Poe the Raven. live under one roof. Danny's drinking partners are Quest, Tarzan, and Nero. Quest is married to Jessie.
- Fanboy and Chum Chum: Drew and Chopper are wannabe superheroes.
- Father of the Pride: The tale of Mr. Chairman, his wife Margaret White and child Velma. Velma's grandfather Reuben Tishkoff visits. Masters of the Impossible Ryuk and Dudley Puppy are also there.
- Fish Hooks: Lazlo, Snails, and Macy Misa are fish attending high school.
- Foster's Home for Imaginary Friends: Baljeet brings his imaginary friend Angel Face to a special home.
- Freakazoid!: J.B. can become superhero Justin Bieber!
- Futurama: P.J. is unfrozen a millennium into the future, and then goes to work for a space courier crew that includes the Joker, Pocoyo, Cordell Walker, Eddy (later Scooby-Doo), and Lizzie McGuire (later Rangiku Matsumoto).
- Gargoyles: Lucius Fox leads Homer Simpson, Bugs Bunny, Colt Seavers, and Scotty to protect New York City against Red Forman, Principal Waxelplax, and Jack Donaghy (who is really Tentomon). Santa Claus is a frenemy, while Jasmine and Raphael are their cop friends.
- Generator Rex: Owen is a living bio-weapon.
- Goof Troop: Baloney moves into town with his son Ling-Ling. Their neighbors are Rocky Balboa, The White Witch, Tommy Pickles, and Mindy.
- Gravity Falls: Clemont and Naruto are twins spending their summer vacation in rural Oregon with their great-uncle Discord. Nicole Watterson works at the gift shop, Fanboy is a child psychic, and Brad Buttowski is a crazy old coot.
- Green Lantern: The Animated Series: Influenced by Mung Daal, Robin and a sergeant (later Amon) find their way onto a spaceship voiced by Daphne. Inside Vilgax rules a cult with loyal followers Lola Bunny (later Daisy Duke), Hawkman and Krypto the Superdog, Jerry. Spyro left the cult to assist Robin and the sergeant, recruiting Zatch Bell! and Nicolai. Robin's girlfriend Miss Martian later gets her own powers.
- The Grim Adventures of Billy & Mandy: Trixie Carter and Vinny are two human children who hang out with Death himself, Java.
- Grojband: (Belgium) Singer/guitarist Wander, bassist Armor, drummer Michelangelo, and keyboardist Lightning start a band. Wander's bratty sister Lady Rainicorn, whose best friend is Apple Bloom, crushes on Sunil Nevla.
- Handy Manny: Fez has adventures with his tools, including Hannah Montana, Cow, and Jerry.
- Harvey Beaks: Leah is a little bird who has adventures with her wild best friends Stiles and Twinkle.
- Hey Arnold!: Simon Camden (later Cole Seer) lives in the city with his grandparents Uncle (later Manny) and Yubaba. Simon/Cole's best friend is Andy, but Simon/Cole is often bullied by Fiora, who has a crush on him.
- Hi Hi Puffy AmiYumi: Peg and Gwen start a rock band.
- Hysteria: Iznogoud gathers Kid Goku, Freddie Benson, Pizza Steve, and several other kids to talk about historical figures.
- Jake And The Neverland Pirates: Ben Tennyson, Darby, Erica Reyes, and their talking parrot Ian Hawke look for treasure and fight against Magneto and Hanson.
- Johnny Bravo: Cyril is an Elvis look-alike who always fails at wooing the girls.
- KaBlam!: (probably) Keitaro Urashima and Vicky host a cartoon skit show.
- Kick Buttowski: Captain K'nuckles is the town's most dangerous daredevil. While he gets tormented by his brother Snips, he crushes on Sadie.
- Kid vs. Kat: Rainbow Dash is at war with a cat.
- Kim Possible: Jane and Fix-It Felix Jr. (who was Steve-O in a few episodes) are teenage spies outside of High School. Alongside Voice with an Internet Connection Harry Potter and Felix's pet Donald Duck; they fight many strange villains such as Pumbaa, Gloria, Dr. Octopus, Killer Croc, Master Splinter, Dee-Dee, and Truffles.
- King of the Hill: (France) Anatole and Sheryl Rockmore live in Arlen, Texas with their son Boa Hancock and niece Stella. Their neighbors include Benny, Belly Bag, and Professor Layton.
- (Canada) Ned Flanders and Bart Simpson live together in Arlen with their son Johnny Test and Bart's niece Susan Test. Their Neighbors include Austin Powers, Reggie Dunlop, and Mr. Potato Head. Their Laotian neighbors include Dimirti and and his daughter Anastasia. King Triton is Ned's arrogant father.
- Littlest Pet Shop (2012): Miko Nakadai moves to the big city with her father Andy Dufresne, where she gets a job at the local pet shop; where she meets Talking Animals such as Amber Weaver, Pablo, Gwen, Cody, Nick Mallory, and Lil' Gideon. Bridgette is an Alpha Bitch.
- Little Bear: Peeta Mellark lives in the country side with his parents Miss Finster and Kozo Fuyutsuki.
- Looney Tunes:
- Older dub: Woody Woodpecker is a rascally rabbit who has to deal with a Too Dumb to Live hunter named Greedy Smurf and a western outlaw with a very bad temper named Carface. Joe Dalton is an egotistical duck who often has Darkwing Duck appear as his sidekick. Darth Vader is a cat who wants to eat Calimero and chases after Yoda, the fastest mouse in all of Mexico. Calimero and Vader’s owner is an old woman named Cruella De Vil. Popeye the Sailor is a Martian who wants to get rid of Earth, because it is blocking his view of Venus. General George S. Patton (later Jiminy Cricket) is a loud-mouthed rooster who lives on a farm. Det. Jimmy 'Popeye' Doyle is a Tasmanian devil who eats everything that crosses his path. Danny Tanner is a French skunk who only has eyes for a female cat that is always mistaken for another skunk.
- Current dub that was made during the 90’s: Garfield is a rascally rabbit who has to deal with a Too Dumb to Live hunter named the Vulture/Adrian Toomes and a western outlaw with a very bad temper named Gorgious. Fantasio is an egotistical duck who often has Billy appear as his sidekick. Tigger is a cat who wants to eat Sakura Kinomoto and who chases after Wakko Warner, the fastest mouse in all of Mexico. Sakura and Tigger’s owner is an old woman named Fiona. Wallace is a Martian who wants to get rid of Earth, because it is blocking his view of Venus. Baloo is a loud-mouthed rooster who lives on a farm. Sam is a Tasmanian devil who eats everything that crosses his path. Miles Dyson is a genius coyote who often chases after a bird, although he also chases Garfield every once in a while.
- The Loud House: Bart Simpson lives in a house with his ten sisters: Mipha, Pearl, Coco Bandicoot, Megara, Mina, Gliss, Carla, Alix Kubdel, Fee and Katie Forester.
- MAD: Spider-Man, Brenda Walsh, Schnitzel, Cat, Kole, and Montana Max take part in parody skits.
- The Magic School Bus: (Belgium) Empress Chabi takes Conan Edogawa, Iris, Penny Ling, Dante, Apple Bloom, and three other kids on science field trips. Sometimes Conan's cousin Ikki joins them.
- Martha Speaks: Naruto is a talking dog who lives with his owner PacMan.
- Martin Mystery: Philip J. Fry and Fang solve mysteries with the revived caveman Grim and the alien Stewie Griffin.
- The Marvelous Misadventures of Flapjack: Bakura and Eva raise Konohamaru.
- The Mighty B!: Gwen Tennyson is a bee scout. She lives with her brother the Canadian Rocket Raccoon and mother Marge Simpson.
- The Mighty Ducks: A team of hockey playing ducks (including Wuya) fights the Joker.
- Miraculous Ladybug: Peridot and Meliodas, wielding Transformation Trinkets powered by the respective magic of Nui Harime and Gluttony, are teenaged superheroes who must deal with the schemes of Edmond Dantes.
- Edmond Dantes sends his akuma to corrupt people such as Mulan, Bolin, Nick Russell, Sailor Mercury, April O'Neil, Prince Daniel, Nathan Scott, Neil Gilbert, Miguel Alvarez, Prompto Argentum, Amy Wong, Monk Gyatso, Heero Yuy, Jet Black, Whisper, Alucard, Lucy Heartfilia, Ahri, Cece, Sasha Braus, a voice director, Tim Cross, Joe Kido, Marie Mjolnir and Lola Loud.
- In the Origins Two-Partner, Henry Gibson turns into an Akuma.
- In the Christmas Episode, Fox McCloud is also corrupted by an akuma.
- My Gym Partner's a Monkey: Trixie Tang is a human forced to attend a school for animals run by Brook (later Optimus Prime). Roark is Trixie's gym partner. Skips might be a student.
- My Life as a Teenage Robot: Katara is a teenage robot who hangs out with Xander and his brother Kissyfur. My gut's telling me that Kilgrave has a crush on Katara.
- Packages from Planet X: (Belgium) Denzel Crocker, Tiny, and Clinton receive mysterious packages from outer space.
- Peg + Cat: Iris and Lord Hater teach basic math.
- The Penguins of Madagascar: Bruce Banner, The Ice Truck Killer and Sokka are spy penguins living in the New York Zoo. Apparently a lieutenant, Captain America (who got a new voice after the Captain moved to Canada), and Daggett were reborn as lemurs.
- Phineas and Ferb: Danny Fenton and his silent step-brother Iggy Arbuckle are inventors. Danny's sister Hermione plans to tell their plans to their parents Batgirl and Bloo. Rachel Berry has a crush on Danny. Meanwhile, the boys' pet platypus, upon the orders of Salvador Limones, must defeat the mad scientist Cleveland Brown and his daughter Sari Sumdac. Serenity Zilla is Hermione's best friend, and Hermione has a crush on Ash Ketchum.
- The Powerpuff Girls: David Xanatos creates 3 super-powered girls: Ben Tennyson, Haruhi Suzumiya, and D.J. Tanner.
- ReBoot: Ian McKinley, Plankton (later President Snow), Martha Generic, and Mars are computer programs who save the world from J. Jonah Jameson. Ian's future self is L.
- Recess: Phineas, Alexandra, Phil Diffy, Ed Elric (who sings like Duke Nukem), Romeo, and Misa Amane have adventures on the playground, being watched over by Principal Dawson Leery (later Chet Ubetcha) and yard teacher Emily. Panini helps out the school secretary. Anya tells creepy tales. Gina Simon is a tattletale. Anita Warren and Katara spend their days digging. Minnie Mouse is the gang's quirky fourth grade teacher. Koda's mother, Eris, Abigail Lincoln, and young Hathi are a Girl Posse.
- Regular Show: Toad and Jack Darby work for Trent, alongside Gengar. Toad's girlfriend is Diane Nguyen, and Jack's girlfriend is Jessie.
- The Replacements: Young Kiara and young Simba selected their adopted parents (secret agent Caroline Holden and daredevil Maximus) after a phone call to their uncle. Maximus' talking car is Larry Dittmeyer.
- Rick and Morty: Doc Samson is an alcoholic scientist who takes his grandson, Dipper Pines, on some dangerous adventures through different dimensions of the universe, much to the dismay of Dipper's father and the Doc's son-in-law, Kurama.
- Robot Chicken: Justin, Brick, Lil Gideon, Ronaldo, 1998!Sebastian, Ash Ketchum, Kisame Hoshigaki, Cleopatra, Ulrich, Samson, Kaiba, Griffin, and some others take part in skits.
- Rocket Power: Shinji Ikari, Trina Vega, Matt McGinnis, and Yang do extreme sports.
- Rugrats: Several young children, including Prince Zuko, Batman (later Mandark), Boots, and Padme, have adventures.
- Samurai Jack: Ant-Man, son of Odo, is sent to a Bad Future ruled by the demon Big Bob Pataki (later Rafiki).
- The Secret Saturdays: Cody and Wanda travel the world with their son Coop (as well as Wanda's brother Sasuke Uchiha) as they fight Marilyn Manson.
- The Simpsons
- (France) Real-life couple Brooklyn and Lois Lane live in Springfield with their three children: Shirley the Loon (later Nevel Papperman), Sheila the Thief and a baby. Madame Foster is virtually every other woman/child; General Skarr (later Lex Luthor), Ralph (later Ratigan, then Skipper), and Jar-Jar Binks (later Cosgrove) are the men.
- (Canada) Optimus Prime marries Old Rose and they have 3 children: Pocahontas, B.J., and a baby.
- The Smurfs: Scrooge McDuck tries to catch a race of creatures led by Gonzo. Dory is the only woman for miles.
- Sonic the Hedgehog
- South Park
- Spider-Man: The New Animated Series: Denzel Crocker, Rarity, and Cyclops attend college together. In his spare time, Crocker is a famous crime-fighter.
- SpongeBob SquarePants: Johan Liebert lives in a pineapple. Mr. Garrison (later Fonzie) and Gary (later Sparky) are his neighbors; J. Jonah Jameson is his own business rival, and Mimi (later Ms. Frizzle) is virtually every female.
- Squirrel Boy Ash Ketchum is the pet squirrel of a little boy.
- Star Wars Rebels: The Sorcerer, Tyler, Rainbow Dash, Jiraiya, and Martha are a Ragtag Bunch of Misfits that teams up against Professor Oak.
- Star Wars: The Clone Wars
- (France) Stitch is a Jedi in training under Jack Sparrow, who has another apprentice named Buttercup. Together, they fight the Sith warriors, and their adventures are narrated by Launchpad McQuack. (Stitch's love interest is Liberty van Zandt.)
- (Canada) Stitch is once again a wannabe Jedi, but now he is taught by Roger, whose other apprentice is now Caillou. As they fight the evil Sith, their narrator is J. Jonah Jameson. (Stitch's love interest is Susan Test)
- Static Shock: Fred (or George) Weasley must keep his electric powers a secret from their father. Eventually the twins' friend Shun (later Kakashi) gets his own superpower.
- Steven Universe: Anowak meets three Magical Girls: C.C., Elaine, and Dee Dee. Anowak's father is Exile.
- Superman: The Animated Series: (Disney-style) The Beast (who was Nuka as a teenager), an alien son of Prince Phillip and Kala, Happily Adopted by Muggle Foster Parents Hooft and Pearl, leading a double life as a journalist working alongside Mirage and Max Goof and the world's greatest superhero on the other hand, fighting such threats as Corrupt Corporate Executive Pete, alien collector The Grand Duke, energy eater Kenai, Psycho Electro Jasmine, the most dangerous being omnipotent tyrant Hudson and his son Mr. Incredible.
- Teacher's Pet: Long Feng wants to attend school like his owner Edward Elric.
- Teen Titans: Fred, Arnold, B.O.B., Nina, and Kimmy Schmidt are teenage superheroes. They tried to recruit Jenny, but that failed. Their greatest enemy is Professor X.
- Teenage Mutant Ninja Turtles (1987): Tuxedo Mask trains Puck, Shunsuke (later Trunks), Carl (later Travis Morgan, and Bulk in martial arts as they fight Rocko and Ken.
- Time Squad: Morpheus, a robot, and a little boy time travel to fix the past.
- Transformers Animated: Nia is a little girl who befriends some robots.
- Transformers Prime: Wolverine leads the autobots Raj, Eva, a mute, and the Hulk against the Decepticons Asuma and Marek Ishtar. The Autobots befriend the human kids Oscar, Cedric, and Blythe Baxter, and agent Chef Hatchet.
- Tuff Puppy: Bob and Fifi fight crime. As animals. Uncle Grandpa is their boss.
- Ultimate Spider-Man: Harold is a high school student with spider-based superpowers whose classmates are Vivi and Ty Pennington. Mr. 9 goes undercover as the school's principal. Meanwhile, Optimus Prime takes Harold to team up with Cyclops, Mordecai, Ash Ketchum, and Emma Frost.
- Uncle Grandpa: Mr. Mackey, Lars, the Joker, and Victor go on crazy adventures and entertain kids.
- Wander over Yonder: Corey is a space adventurer.
- We Bare Bears: Randall Boggs, Casey Jones and Sly Cooper are three bears who live in a cave not too far from San Francisco.
- Wow! Wow! Wubbzy!: Emily Elizabeth, Doraemon, and Crow Hogan have adventures in their town.
- Xiaolin Showdown: Kitty Katswell, Rei Ayanami, Dororo, and Po are the apprentices of Donkey and Yupa. Together, they must save the world from SpongeBob SquarePants and Betty Rubble. Shaggy is the Big Bad of season 2.
- Yin Yang Yo!: Niea_7 and Ike are the apprentices of Nute Gunray. Boomhauer is an evil wizard.
- Young Justice: Ron Stoppable, Spike, Howard Wolowitz, Mohinder Suresh, Nico Robin and Julie Mayer form a superteam. Their mentors are the Justice League; featuring heroes such as Aladdin, Dick Danger, Lt. Dan, Valhallen, Thor, Supergirl, Lordgenome, Stifler and Homer Simpson. They then fight a nebulous organization led by immortal Jack Burton.
- The Zeta Project: Shanks the robot and his friend Odd search for the former's creator. They are followed by agents Brock, Dawn, and a narrator.