Notable Roles by Misaki Kuno include:
- Able in Fairy Tail
- Akane Awakusu in Durarara!!
- Al Hokley in Lost Song
- Belphegor in As Miss Beelzebub Likes
- Beni-Enma in Fate/Grand Order
- Bridget Evans in Oreimo
- Camieux in Granblue Fantasy
- Cryosphere in Mighty No. 9
- Didier Lydianne in Strike the Blood
- Elfnein in Senki Zesshou Symphogear
- Young Emily Thorn/Amanda Clarke in the Japanese dub of Revenge
- GGK in Carole & Tuesday
- Harumi Ayasato (Pearl Fey) in the anime adaptation of Ace Attorney
- Hawk in The Seven Deadly Sins
- Hisone Amakasu in Hisone and Masotan
- Hugo in The Ancient Magus' Bride
- Iris Watson in Dai Gyakuten Saiban: Naruhodou Ryuunosuke no Bouken
- Kino Yakobe in Senryu Girl
- Kurumi Kumamakura in Myriad Colors Phantom World
- Littorio and Roma in Kantai Collection
- Lupine (Mirabilis) in Fire Emblem Heroes
- Mao in Endro~!
- Merun in Problem Children Are Coming from Another World, Aren't They?
- Mimi Balguerie in RO-KYU-BU! SS
- Momo Kawamoto in 3-gatsu no Lion
- Nico Niyama in Kiznaiver
- Nina Ichihara in THE iDOLM@STER: Cinderella Girls
- Orangor in Tenkai Knights
- Poppi in Xenoblade Chronicles 2
- Roko in Mysterious Joker
- Sakura Fujimiya in Battle Girl High School
- Serena in Log Horizon
- Shinonon in Utawarerumono
- Shio Koube in Happy Sugar Life
- Sophia in Persona 5 Scramble: The Phantom Strikers
- Tama in Selector Infected WIXOSS
- Toki in Shin Megami Tensei IV: Apocalypse
- Yukari Komori in Seton Academy: Join the Pack!
