Dr. Roy Curien
Warden Clement Darling
The ChariotA large zombie wearing a full suit of armor, who is the first boss fought in the first game.
The HangedmanA flying stone gargoyle who kidnaps Rogan's girlfriend and later attacks him and G on the roof. He's the second boss of the first game.
The MagicianCurien's most powerful creation, which is a mutant with fire control and psychic powers. The fourth (and final) boss of the first game. It later serves as the fifth boss of the second game, and the second (and once again final) boss of The House of the Dead 4 Special.
JudgementA small imp (Zeal) and a living suit of Armor (Kuarl), who are met in Venice by James and Gary. It's the first boss in The House of the Dead 2.
The HierophantA triton-like zombie armed with a trident. The second boss of the second game.
The TowerA Hydra-like mutant who dwells in the sewers of Venice. The third boss of the second game.
StrengthA huge, chainsaw-wielding brute fought in a Coliseum. The fourth boss of the second game.
The EmperorA humanoid being made of shapeshifting molten metal, and Goldman's last creature. The sixth (and final) boss of the second game.
DeathA huge skull-faced mutant dressed as a Security Guard and armed with a club. He'll chase G and Lisa for two levels. One of the bosses in the third game.
The FoolA mutated giant sloth who resides in a well-like cage inside the building. One of the bosses in the third game.
The SunA mutant giant plant with many tentacle-like roots and human faces on its stalk. One of the bosses in the third game.
The Wheel Of FateCurien's ultimate creation/transformation, it is a cybernetic monster surrounded by a metal ring. It manipulates electricity to fight. It's the final boss of The House of the Dead 3, and is actually Dr. Roy Curien himself.
JusticeA huge, four-armed mutant that chases Kate and James in the sewers. The first boss of The House of the Dead 4 and The House of the Dead 4 Special Edition.
The LoversA pair of mutated Tarantulas which attack Kate and James as they try to leave the underground via Elevator. The second boss of The House of the Dead 4.
The EmpressA powerful purple zombie armed with a ludicrously big double-chainsaw. He/she chases Kate and James on the train. The third boss of the fourth game.
TemperanceA morbidly obese, giant zombie that chases our heroes down the streets. He's so fat that bullets won't damage him. The fourth boss of the fourth game.
The StarA humanoid mutant armed with swords and a purple aura, which acts as a "test" of strength for Kate and James. When he dies, he wounds James with a shard of his body. He's a perfected model of The Magician, and the fifth boss of The House of the Dead 4.
The WorldGoldman's last trick, which is a powerful, constantly-evolving monster made of ice. He's destroyed by James's sacrifice.
Jasper GunnsThe first boss in OVERKILL, he's Varla's quadriplegic younger brother, who has injected himself with a Psycho Serum in order to kill Papa Caesar, but got distracted by G and Issac, allowing Caesar to escape. Unfortunately, Jasper ends up so far gone that he can't tell ally from enemy, and ends up attacking G and Issac instead.
Coco and SindyExclusive for the Playstation 3 version, they're Varla Guns' fellow coworkers who borrowed Varla's bike before getting infected. Appears as a fat woman and a skinny woman. Chronologically the second boss fought in the PS3 version.
The ScreamerAnother creation of Caesar, who's released in a hospital in order to kill G and Isaac. Appears as a zombie girl with a mutilated face and powerful screams. The second boss in OVERKILL (third if you count the PS3 version).
Nigel and SebastianA pair of circus freaks mutated by the virus, who are now feeding on corpses in the circus. Nigel is the large guy, while Sebastian is the tumor-like thing embedded in his belly. The third boss of OVERKILL (fourth in the PS3 version).
Meat KatieExclusive in the PS3 version, it is a gigantic cow-like mutant who wields a butcher's knife in the butcher shop. Chronologically the fifth boss of the game.
The CrawlerA huge mutant similar to a bug, it attacks Isaac and G on the train. The fourth boss of OVERKILL (sixth in the PS3 version).
The LobberA massive frog-like mutant who's infesting the swamps. The fifth boss of OVERKILL (seventh in the PS3 version).
BrutusA huge, mutated criminal who was executed for his many awful crimes. He's seen together with another similar mutant, who he kills. The sixth boss of OVERKILL (eighth in the PS3 version).
MotherClement Darling's mother, who was exposed to the compound and had her brain put in Varla's body. She mutates to a giant, grotesque monster which births smaller mutants from her oversized vagina. The seventh and final boss of OVERKILL (ninth and tenth if you count the playable "Missing Reel" in the PS3 version).