Ratched is just a nurse trying to do her job as well as she knows how; McMurphy, a racist, sexist and statutory rapist, insists on causing mayhem on her ward.
McMurphy himself, who is diagnosed in the play with a pathological need to flout authority and be the center of attention... Which seems about right.
Complete Monster: Ratched, the "Big Nurse", is the cruel head of the state hospital the story takes place in, using her connections to her superiors to allow herself free rein over the hospital. Ratched subjects her dozens of patients to horrific conditions and abuse, employing brutal lackeys and methods to keep patients in line and under her thumb, uncaring of the countless patients who commit suicide or self-mutilation due to her rule. Believing that her patients have to be perfectly-functioning before allowing them to leave, Ratched often resorts to electroshock treatments and even lobotomies to destroy her patients' minds. When her rule is challenged over and over again by Randle McMurphy, Ratched increases her abuse of the patients to the point that one of McMurphy's friends kills himself. Though Ratched's control over the patients is broken, she spitefully has McMurphy lobotomized in a last-ditch effort to terrorize the patients into falling back in line.
Harsher in Hindsight: An in-universe example is the scene where McMurphy shows up glassy-eyed and uncoordinated following his electroshock treatment as a joke on the other inmates. It's played for laughs, but it's much less comical in hindsight because Mack is mimicking the very state that he winds up in at the end following his lobotomy.
Plenty in the novel, but not between any specific characters and used more to build up the discomforting, emasculating atmosphere of the hospital than to establish the sweetly ambiguous kinds of relationships that the trope is associated with.
The orderlies. According to Bromden, they love to give patients showers. They always check the patient's temperature at the same time they shower the patient, and they go down to Miss Ratched beforehand to get a rectal thermometer and a bottle of Vaseline. She admonishes them to use the minimum amount of Vaseline necessary, but they take the whole bottle inside with them, and they turn up the water pressure till the noise makes it impossible to hear anything that's going on inside...
Nurse Ratched has been on the wrong end of the moral event horizon for many years, as she is seen to submit her charges to torture for crossing her (the scene with the germophobe after the fishing trip, the forced anal administration of medication to a patient merely because he questioned what the pills were for), the electroshock 'therapy', and she has also lobotomized patients as punishment for behavior she dislikes. Nurse Ratched is utterly monstrous in the book.
Of course, given the book's expert use of Unreliable Narrator, it's hard to tell if she really is that bad or if it's the Chief projecting onto her. Remember, he also thinks that the orderlies are evil robots.
The African-American orderlies are treated indelicately by the narrative , and McMurphy even drops an N-Bomb. In the book, the orderlies are overtly thugs and rapists.
Many people find the book to be misogynist, what with and the idea that matriarchy is akin to castration, and the implication that no woman could/should dominate a "real man." Prostitution and McMurphy's statutory rape charge are treated pretty casually. Ratched's violent comeuppance is, in the book, very sexualized and supposed to be seen as a moment of dishing out truly justified retribution.
McMurphy's charge of statutory rape—in the time the book was written, it wasn't as serious a crime. McMurphy also alleges she told him she was eighteen, and he wasn't found guilty of it, but he does brag about it. The book and movie asks you to see him as an admirable anti-authority figure.
The Woobie: Every character that's not Nurse Ratched or McMurphy at least until the end. Charlie Cheswick and Billy Bibbit especially, on account of being Driven to Suicide, as well as Chief Bromden, on account of his social isolation on the ward and his family's tragic backstory.
Except that Nurse Ratched seems to believe that her job is "to have absolute power over the patients in my ward", not "to care for the patients in my ward". Her failure to do the latter and her insistence on doing the former is what causes the situation to get out of control.
McMurphy is really a Decoy Protagonist while the movie was really about Chief Bromden finding the courage to escape from the mental institution.
Four or five different directors came to me with that at different times. I go, "It's not a movie. Who wants to look at four institution walls?" Miloš Forman made it great. Jack was great in it. I made a flat-out, fucking mistake.
Anvilicious: This is one of the first films to criticize the way people with mental illness are mistreated by mental hospitals, especially in this time period it takes place in. Nurse Ratched using electroshock-therapy (without anesthesia) was a common practice in mental wards as a way to punish “difficult” patients, or to just make them easier to handle. This was often the same reason for lobotomies, which is what happens to McMurphy at the end. Indeed, these procedures would later be classified as medical torture by international healthcare laws.
Award Snub: While the film swept the major Oscar categories, many still believe Brad Dourif was robbed for not winning Best Supporting Actor for his role as Billy Bibbit.
Draco in Leather Pants: Many viewers see Nurse Ratched as just a somewhat mean nurse who is just doing her job the only way she knows how. This negates the fact that Ratched is not trying to help her patients, but control them, and that she represents a widespread problem within mental wards at the time of the story: that dangerous and invasive medical procedures were often used to punish patients instead of help them. A lot of this may be due to the protagonist being Unintentionally Unsympathetic due to Values Dissonance, but this doesn’t make Ratched’s actions any less reprehensible. Viewers also seem to miss the subtle ways she humiliates her patients, and how she often starts conflicts between them for no reason.
Estrogen Brigade: Billy Bibbit has quite the female fandom, probably due to his Moe status, though being played by a young, cute Brad Dourif doesn't hurt.
Nicholson and Turkle's actor, Scatman Crothers, would also both later star in another film that centers around isolation and insanity and features Nicholson's character dying at the end. This gets even more amusing when factoring in Miloš Forman's original plan to have Shelley Duvall play Candy.
In the film, there's Billy/McMurphy. McMurphy even says to Candy something like, "I just want you to do this one thing for me. He's cute, isn't he?"
In the film, much of Sefelt and Fredrickson's interactions-such as their inseparability, how Fredrickson is always touching the older man, them dancing together at the party, and them passing out with their beds pushed together afterwards- can be seen as this
Moral Event Horizon: Nurse Ratched might just be a mean and misguided nurse trying to do her job, right up until the point where she threatens to tell Billy's mother about his "bad behaviour", knowing full well the trauma that would cause him, which leads to his suicide.
Unintentionally Unsympathetic: McMurphy. We're supposed to see him as an admirable anti-authority figure even though he's loud, obnoxious, casually racist, and sexist and he had no qualms about conning his fellow patients (who he also mocks and berates) out of their money. Not only that but the entire reason he's at the asylum in the first place is so that he can avoid going to prison on statutory rape charges.